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The article discusses a research which identified sex-related and non-sex-related comorbidity and psychopathological subtypes of Gilles de la Tourette syndrome (GTS) and other tic disorders using latent class analysis (LCA) in a community-based cohort. It has found that depression was highly prevalent in all GTS classes. An overview of the relationship between sex and GTS is provided.

Presents several poems by Mary May Robertson. "Chemo Aftermath"; First Line: I'm tired and yet; Last Line: Will it ever go? "Cocoon"; First Line: My life now seems safe only in; Last Line: Forever. "Hospitals"; First Line: Hospitals are horrible. Last Line: My left breast cells go to the path lab.

Patients affected by epilepsy show a considerably higher incidence of depression compared with the general population. Since women are twice as likely as men to suffer from depression, female gender could be considered a major risk factor for developing this condition. Converging lines of evidence suggest that sex hormones, which are known to contribute to remodelling the hippocampus, play a pivotal role in both epilepsy and depression. In women, the role of sex hormone levels may be more important because of their physiological cyclic fluctuations. Oestrogens, more than other ovarian hormones, show an effect similar to antidepressant drugs by stimulating hippocampal synaptogenesis, thus exerting a protective role against seizures as well. This paper reviews the current knowledge on the neurobiological basis of depression in women with epilepsy. The emerging picture informs therapeutic strategies to improve the clinical management of this common comorbidity.