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386 results on '"Robert, Lucie"'

5. Chronologie

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

8. Les librairies

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

10. Les chroniques

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

12. L'histoire

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

15. La radio

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

17. Les périodiques

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

20. Les agents

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

26. Introduction

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

27. Remerciements

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

28. Présentation

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

35. 7. La réception

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

38. Bibliographie

Author

Robert, Lucie and Saint-Jacques, Denis

Published
2011

41. Development of sensitive and robust multiplex digital PCR assays for the detection of ESR1 mutations in the plasma of metastatic breast cancer patients

Author

Corné, Julien, Quillien, Véronique, Callens, Céline, Portois, Pascal, Bidard, François-Clément, Jeannot, Emmanuelle, Godey, Florence, Le Du, Fanny, Robert, Lucie, Bourien, Héloïse, Brunot, Angélique, Crouzet, Laurence, Perrin, Christophe, Lefeuvre-Plesse, Claudia, Diéras, Véronique, and de la Motte Rouge, Thibault

Published
2023
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43. Plasma‐based analysis of ERBB2 mutational status by multiplex digital PCR in a large series of patients with metastatic breast cancer.

Author

Corné, Julien, Quillien, Véronique, Godey, Florence, Cherel, Mathilde, Cochet, Agathe, Le Du, Fanny, Robert, Lucie, Bourien, Héloïse, Brunot, Angélique, Crouzet, Laurence, Perrin, Christophe, Lefeuvre‐Plesse, Claudia, Diéras, Véronique, and De la Motte Rouge, Thibault

Abstract

Erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐activating mutations are therapeutically actionable alterations found in various cancers, including metastatic breast cancer (MBC). We developed multiplex digital PCR assays to detect and quantify ERBB2 mutations in circulating tumor DNA from liquid biopsies. We studied the plasma from 272 patients with hormone‐receptor‐positive, human epidermal growth factor receptor 2‐negative (HR+/HER2−) MBC to detect 17 ERBB2 mutations using a screening assay. The assay was developed on the three‐color Crystal dPCR™ naica® platform with a two‐step strategy for precise mutation identification. We found that nine patients (3.3%) harbored at least one ERBB2 mutation. The mutation rate was higher in patients with lobular histology (5.9%) compared to invasive breast carcinoma of no special type (2.6%). A total of 12 mutations were found with the following frequencies: L755S (25.00%), V777L (25.00%), S310Y (16.67%), L869R (16.67%), S310F (8.33%), and D769H (8.33%). Matched tumor samples from six patients identified the same mutations with an 83% concordance rate. In summary, our highly sensitive multiplex digital PCR assays are well suited for plasma‐based monitoring of ERBB2 mutational status in patients with MBC. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Table S3 from CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Author

Fattori, Stéphane, primary, Le Roy, Aude, primary, Houacine, Jemila, primary, Robert, Lucie, primary, Abes, Riad, primary, Gorvel, Laurent, primary, Granjeaud, Samuel, primary, Rouvière, Marie-Sarah, primary, Ben Amara, Amira, primary, Boucherit, Nicolas, primary, Tarpin, Carole, primary, Pakradouni, Jihane, primary, Charafe-Jauffret, Emmanuelle, primary, Houvenaeghel, Gilles, primary, Lambaudie, Eric, primary, Bertucci, François, primary, Rochigneux, Philippe, primary, Gonçalves, Anthony, primary, Foussat, Arnaud, primary, Chrétien, Anne-Sophie, primary, and Olive, Daniel, primary

Published
2023
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48. Supplementary_Materials_and_Methods_Figures_and_Figure_legends from CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Author

Fattori, Stéphane, primary, Le Roy, Aude, primary, Houacine, Jemila, primary, Robert, Lucie, primary, Abes, Riad, primary, Gorvel, Laurent, primary, Granjeaud, Samuel, primary, Rouvière, Marie-Sarah, primary, Ben Amara, Amira, primary, Boucherit, Nicolas, primary, Tarpin, Carole, primary, Pakradouni, Jihane, primary, Charafe-Jauffret, Emmanuelle, primary, Houvenaeghel, Gilles, primary, Lambaudie, Eric, primary, Bertucci, François, primary, Rochigneux, Philippe, primary, Gonçalves, Anthony, primary, Foussat, Arnaud, primary, Chrétien, Anne-Sophie, primary, and Olive, Daniel, primary

Published
2023
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49. Data from CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Author

Fattori, Stéphane, primary, Le Roy, Aude, primary, Houacine, Jemila, primary, Robert, Lucie, primary, Abes, Riad, primary, Gorvel, Laurent, primary, Granjeaud, Samuel, primary, Rouvière, Marie-Sarah, primary, Ben Amara, Amira, primary, Boucherit, Nicolas, primary, Tarpin, Carole, primary, Pakradouni, Jihane, primary, Charafe-Jauffret, Emmanuelle, primary, Houvenaeghel, Gilles, primary, Lambaudie, Eric, primary, Bertucci, François, primary, Rochigneux, Philippe, primary, Gonçalves, Anthony, primary, Foussat, Arnaud, primary, Chrétien, Anne-Sophie, primary, and Olive, Daniel, primary

Published
2023
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50. File_S1 from CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Author

Fattori, Stéphane, primary, Le Roy, Aude, primary, Houacine, Jemila, primary, Robert, Lucie, primary, Abes, Riad, primary, Gorvel, Laurent, primary, Granjeaud, Samuel, primary, Rouvière, Marie-Sarah, primary, Ben Amara, Amira, primary, Boucherit, Nicolas, primary, Tarpin, Carole, primary, Pakradouni, Jihane, primary, Charafe-Jauffret, Emmanuelle, primary, Houvenaeghel, Gilles, primary, Lambaudie, Eric, primary, Bertucci, François, primary, Rochigneux, Philippe, primary, Gonçalves, Anthony, primary, Foussat, Arnaud, primary, Chrétien, Anne-Sophie, primary, and Olive, Daniel, primary

Published
2023
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