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31. Full-Sternotomy Off-Pump versus On-Pump Coronary Artery Bypass Procedures: In-Hospital Outcomes and Complications during One Year in a Single Center

Author

TOMASO BOTTIO, Rizzoli, G., Caprili, L., Nesseris, G., Thiene, G., and Gerosa, G.

Subjects
Adult, Aged, 80 and over, Male, Cardiopulmonary Bypass, Coronary Artery Disease, Middle Aged, Postoperative Complications, Treatment Outcome, Editorial, Thoracotomy, Humans, Female, Hospital Mortality, Prospective Studies, Clinical Investigation, Coronary Artery Bypass, Aged, Follow-Up Studies
Abstract

We prospectively compared, according to their preoperative clinical profiles, the in-hospital outcomes of patients operated on consecutively (but without randomization) for isolated coronary artery disease with on-pump or off-pump techniques. During 2001, 324 patients underwent coronary artery bypass grafting: 216 patients (mean age, 66.7 +/- 8.9 years; range, 41-85 years) underwent on-pump revascularization, and 108 patients (mean age, 676 +/- 10 years; range, 37-90 years) underwent full-sternotomy off-pump revascularization. The 2 groups were homogeneous with regard to female sex (22.6% vs 26.8%), previous cardiac operation (2.8% vs 4.6%), cardiogenic shock (1.3% vs 1.9%), diabetes (30% vs 33%), and chronic renal failure that required hemodialysis (3% vs 3.5%). Postoperative complications, including bleeding, myocardial infarction, acute renal failure, mediastinitis with sternal dehiscence, cerebrovascular events, and prolonged respiratory assistance were more frequent in on-pump patients (P = 0.004). The total number of grafts and the grafts per patient ratio were significantly higher in on-pump patients (P = 0.0001), whereas the total number of full arterial revascularizations was higher in off-pump patients (P = 0.0001). Off-pump patients showed a significantly shorter intensive care unit stay (P = 0.02), and less need for intra-aortic balloon pump insertion (P = 0.04). In-hospital mortality was 2.8% in on-pump patients and 2.7% in off-pump patients (P = NS). Although the hospital mortality rate was comparable for the 2 techniques, the in-hospital comparison between the 2 groups showed how the avoidance of cardiopulmonary bypass can significantly reduce the cumulative postoperative incidence of complications in patients undergoing coronary artery bypass grafting.

Published
2003

32. Compositional changes of a brushite hydraulic cement after implantation in sheep

Author

Bohner, M, Theiss, Felix, Apelt, D, Hirsiger, W, Houriet, R, Rizzoli, G, Gnos, E, Frei, C, Auer, Jörg A, von Rechenberg, Brigitte, University of Zurich, and Bohner, M

Subjects
2211 Mechanics of Materials, 630 Agriculture, 1502 Bioengineering, 2502 Biomaterials, 570 Life sciences, biology, 2503 Ceramics and Composites, 10090 Equine Department, 1304 Biophysics
Published
2003

42. Long -term results of mitral commissurotomy

Author

Scalia, Rizzoli, G., Campanile, F., Melacini, P., Villanova, C., Milano, Aldo Domenico, Fasoli, G., Mazzucco, Alessandro, and Casarotto, Dino Carlo

Published
1993

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