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1. Effect of remote ischemic conditioning on the immune-inflammatory profile in patients with traumatic hemorrhagic shock in a randomized controlled trial

Author: Leung, C. H., Rizoli, S. B., Trypcic, S., Rhind, S. G., Battista, A. P., Ailenberg, M., and Rotstein, O. D.
Published: 2023
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2. Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS)

Author: Picetti, E, Demetriades, A, Catena, F, Aarabi, B, Abu-Zidan, F, Alves, O, Ansaloni, L, Armonda, R, Badenes, R, Bala, M, Balogh, Z, Barbanera, A, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Castano-Leon, A, Cerasti, D, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Costa, F, De Iure, F, Depreitere, B, Fainardi, E, Fehlings, M, Gabrovsky, N, Godoy, D, Gruen, P, Gupta, D, Hawryluk, G, Helbok, R, Hossain, I, Hutchinson, P, Iaccarino, C, Inaba, K, Ivanov, M, Kaprovoy, S, Kirkpatrick, A, Klein, S, Kolias, A, Konovalov, N, Lagares, A, Lippa, L, Loza-Gomez, A, Luoto, T, Maas, A, Maciejczak, A, Maier, R, Marklund, N, Martin, M, Melloni, I, Mendoza-Lattes, S, Meyfroidt, G, Munari, M, Napolitano, L, Okonkwo, D, Otomo, Y, Papadopoulos, M, Petr, O, Peul, W, Pudkrong, A, Qasim, Z, Rasulo, F, Reizinho, C, Ringel, F, Rizoli, S, Rostami, E, Rubiano, A, Russo, E, Sarwal, A, Schwab, J, Servadei, F, Sharma, D, Sharif, S, Shiban, E, Shutter, L, Stahel, P, Taccone, F, Terpolilli, N, Thomé, C, Toth, P, Tsitsopoulos, P, Udy, A, Vaccaro, A, Varon, A, Vavilala, M, Younsi, A, Zackova, M, Zoerle, T, Robba, C, Picetti, Edoardo, Demetriades, Andreas K., Catena, Fausto, Aarabi, Bizhan, Abu-Zidan, Fikri M., Alves, Oscar L., Ansaloni, Luca, Armonda, Rocco A., Badenes, Rafael, Bala, Miklosh, Balogh, Zsolt J., Barbanera, Andrea, Bertuccio, Alessandro, Biffl, Walter L., Bouzat, Pierre, Buki, Andras, Castano-Leon, Ana Maria, Cerasti, Davide, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Costa, Francesco, De Iure, Federico, Depreitere, Bart, Fainardi, Enrico, Fehlings, Michael J., Gabrovsky, Nikolay, Godoy, Daniel Agustin, Gruen, Peter, Gupta, Deepak, Hawryluk, Gregory W. J., Helbok, Raimund, Hossain, Iftakher, Hutchinson, Peter J., Iaccarino, Corrado, Inaba, Kenji, Ivanov, Marcel, Kaprovoy, Stanislav, Kirkpatrick, Andrew W., Klein, Sam, Kolias, Angelos, Konovalov, Nikolay A., Lagares, Alfonso, Lippa, Laura, Loza-Gomez, Angelica, Luoto, Teemu M., Maas, Andrew I. R., Maciejczak, Andrzej, Maier, Ronald V., Marklund, Niklas, Martin, Matthew J., Melloni, Ilaria, Mendoza-Lattes, Sergio, Meyfroidt, Geert, Munari, Marina, Napolitano, Lena M., Okonkwo, David O., Otomo, Yasuhiro, Papadopoulos, Marios C., Petr, Ondra, Peul, Wilco C., Pudkrong, Aichholz K., Qasim, Zaffer, Rasulo, Frank, Reizinho, Carla, Ringel, Florian, Rizoli, Sandro, Rostami, Elham, Rubiano, Andres M., Russo, Emanuele, Sarwal, Aarti, Schwab, Jan M., Servadei, Franco, Sharma, Deepak, Sharif, Salman, Shiban, Ehab, Shutter, Lori, Stahel, Philip F., Taccone, Fabio S., Terpolilli, Nicole A., Thomé, Claudius, Toth, Peter, Tsitsopoulos, Parmenion P., Udy, Andrew, Vaccaro, Alexander R., Varon, Albert J., Vavilala, Monica S., Younsi, Alexander, Zackova, Monika, Zoerle, Tommaso, Robba, Chiara, Picetti, E, Demetriades, A, Catena, F, Aarabi, B, Abu-Zidan, F, Alves, O, Ansaloni, L, Armonda, R, Badenes, R, Bala, M, Balogh, Z, Barbanera, A, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Castano-Leon, A, Cerasti, D, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Costa, F, De Iure, F, Depreitere, B, Fainardi, E, Fehlings, M, Gabrovsky, N, Godoy, D, Gruen, P, Gupta, D, Hawryluk, G, Helbok, R, Hossain, I, Hutchinson, P, Iaccarino, C, Inaba, K, Ivanov, M, Kaprovoy, S, Kirkpatrick, A, Klein, S, Kolias, A, Konovalov, N, Lagares, A, Lippa, L, Loza-Gomez, A, Luoto, T, Maas, A, Maciejczak, A, Maier, R, Marklund, N, Martin, M, Melloni, I, Mendoza-Lattes, S, Meyfroidt, G, Munari, M, Napolitano, L, Okonkwo, D, Otomo, Y, Papadopoulos, M, Petr, O, Peul, W, Pudkrong, A, Qasim, Z, Rasulo, F, Reizinho, C, Ringel, F, Rizoli, S, Rostami, E, Rubiano, A, Russo, E, Sarwal, A, Schwab, J, Servadei, F, Sharma, D, Sharif, S, Shiban, E, Shutter, L, Stahel, P, Taccone, F, Terpolilli, N, Thomé, C, Toth, P, Tsitsopoulos, P, Udy, A, Vaccaro, A, Varon, A, Vavilala, M, Younsi, A, Zackova, M, Zoerle, T, Robba, C, Picetti, Edoardo, Demetriades, Andreas K., Catena, Fausto, Aarabi, Bizhan, Abu-Zidan, Fikri M., Alves, Oscar L., Ansaloni, Luca, Armonda, Rocco A., Badenes, Rafael, Bala, Miklosh, Balogh, Zsolt J., Barbanera, Andrea, Bertuccio, Alessandro, Biffl, Walter L., Bouzat, Pierre, Buki, Andras, Castano-Leon, Ana Maria, Cerasti, Davide, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Costa, Francesco, De Iure, Federico, Depreitere, Bart, Fainardi, Enrico, Fehlings, Michael J., Gabrovsky, Nikolay, Godoy, Daniel Agustin, Gruen, Peter, Gupta, Deepak, Hawryluk, Gregory W. J., Helbok, Raimund, Hossain, Iftakher, Hutchinson, Peter J., Iaccarino, Corrado, Inaba, Kenji, Ivanov, Marcel, Kaprovoy, Stanislav, Kirkpatrick, Andrew W., Klein, Sam, Kolias, Angelos, Konovalov, Nikolay A., Lagares, Alfonso, Lippa, Laura, Loza-Gomez, Angelica, Luoto, Teemu M., Maas, Andrew I. R., Maciejczak, Andrzej, Maier, Ronald V., Marklund, Niklas, Martin, Matthew J., Melloni, Ilaria, Mendoza-Lattes, Sergio, Meyfroidt, Geert, Munari, Marina, Napolitano, Lena M., Okonkwo, David O., Otomo, Yasuhiro, Papadopoulos, Marios C., Petr, Ondra, Peul, Wilco C., Pudkrong, Aichholz K., Qasim, Zaffer, Rasulo, Frank, Reizinho, Carla, Ringel, Florian, Rizoli, Sandro, Rostami, Elham, Rubiano, Andres M., Russo, Emanuele, Sarwal, Aarti, Schwab, Jan M., Servadei, Franco, Sharma, Deepak, Sharif, Salman, Shiban, Ehab, Shutter, Lori, Stahel, Philip F., Taccone, Fabio S., Terpolilli, Nicole A., Thomé, Claudius, Toth, Peter, Tsitsopoulos, Parmenion P., Udy, Andrew, Vaccaro, Alexander R., Varon, Albert J., Vavilala, Monica S., Younsi, Alexander, Zackova, Monika, Zoerle, Tommaso, and Robba, Chiara
Abstract: Background: The early management of polytrauma patients with traumatic spinal cord injury (tSCI) is a major challenge. Sparse data is available to provide optimal care in this scenario and worldwide variability in clinical practice has been documented in recent studies. Methods: A multidisciplinary consensus panel of physicians selected for their established clinical and scientific expertise in the acute management of tSCI polytrauma patients with different specializations was established. The World Society of Emergency Surgery (WSES) and the European Association of Neurosurgical Societies (EANS) endorsed the consensus, and a modified Delphi approach was adopted. Results: A total of 17 statements were proposed and discussed. A consensus was reached generating 17 recommendations (16 strong and 1 weak). Conclusions: This consensus provides practical recommendations to support a clinician’s decision making in the management of tSCI polytrauma patients.
Published: 2024

3. ECLAPTE: Effective Closure of LAParoTomy in Emergency-2023 World Society of Emergency Surgery guidelines for the closure of laparotomy in emergency settings

Author: Frassini, S, Cobianchi, L, Fugazzola, P, Biffl, W, Coccolini, F, Damaskos, D, Moore, E, Kluger, Y, Ceresoli, M, Coimbra, R, Davies, J, Kirkpatrick, A, Di Carlo, I, Hardcastle, T, Isik, A, Chiarugi, M, Gurusamy, K, Maier, R, Segovia Lohse, H, Jeekel, H, Boermeester, M, Abu-Zidan, F, Inaba, K, Weber, D, Augustin, G, Bonavina, L, Velmahos, G, Sartelli, M, Di Saverio, S, Ten Broek, R, Granieri, S, Dal Mas, F, Fare, C, Peverada, J, Zanghi, S, Vigano, J, Tomasoni, M, Dominioni, T, Cicuttin, E, Hecker, A, Tebala, G, Galante, J, Wani, I, Khokha, V, Sugrue, M, Scalea, T, Tan, E, Malangoni, M, Pararas, N, Podda, M, De Simone, B, Ivatury, R, Cui, Y, Kashuk, J, Peitzman, A, Kim, F, Pikoulis, E, Sganga, G, Chiara, O, Kelly, M, Marzi, I, Picetti, E, Agnoletti, V, De'Angelis, N, Campanelli, G, de Moya, M, Litvin, A, Martinez-Perez, A, Sall, I, Rizoli, S, Tomadze, G, Sakakushev, B, Stahel, P, Civil, I, Shelat, V, Costa, D, Chichom-Mefire, A, Latifi, R, Chirica, M, Amico, F, Pardhan, A, Seenarain, V, Boyapati, N, Hatz, B, Ackermann, T, Abeyasundara, S, Fenton, L, Plani, F, Sarvepalli, R, Rouhbakhshfar, O, Caleo, P, Ho-Ching Yau, V, Clement, K, Christou, E, Castillo, A, Gosal, P, Balasubramaniam, S, Hsu, J, Banphawatanarak, K, Pisano, M, Adriana, T, Michele, A, Cioffi, S, Spota, A, Catena, F, Ansaloni, L, Frassini S., Cobianchi L., Fugazzola P., Biffl W. L., Coccolini F., Damaskos D., Moore E. E., Kluger Y., Ceresoli M., Coimbra R., Davies J., Kirkpatrick A., Di Carlo I., Hardcastle T. C., Isik A., Chiarugi M., Gurusamy K., Maier R. V., Segovia Lohse H. A., Jeekel H., Boermeester M. A., Abu-Zidan F., Inaba K., Weber D. G., Augustin G., Bonavina L., Velmahos G., Sartelli M., Di Saverio S., Ten Broek R. P. G., Granieri S., Dal Mas F., Fare C. N., Peverada J., Zanghi S., Vigano J., Tomasoni M., Dominioni T., Cicuttin E., Hecker A., Tebala G. D., Galante J. M., Wani I., Khokha V., Sugrue M., Scalea T. M., Tan E., Malangoni M. A., Pararas N., Podda M., De Simone B., Ivatury R., Cui Y., Kashuk J., Peitzman A., Kim F., Pikoulis E., Sganga G., Chiara O., Kelly M. D., Marzi I., Picetti E., Agnoletti V., De'Angelis N., Campanelli G., de Moya M., Litvin A., Martinez-Perez A., Sall I., Rizoli S., Tomadze G., Sakakushev B., Stahel P. F., Civil I., Shelat V., Costa D., Chichom-Mefire A., Latifi R., Chirica M., Amico F., Pardhan A., Seenarain V., Boyapati N., Hatz B., Ackermann T., Abeyasundara S., Fenton L., Plani F., Sarvepalli R., Rouhbakhshfar O., Caleo P., Ho-Ching Yau V., Clement K., Christou E., Castillo A. M. G., Gosal P. K. S., Balasubramaniam S., Hsu J., Banphawatanarak K., Pisano M., Adriana T., Michele A., Cioffi S. P. B., Spota A., Catena F., Ansaloni L., Frassini, S, Cobianchi, L, Fugazzola, P, Biffl, W, Coccolini, F, Damaskos, D, Moore, E, Kluger, Y, Ceresoli, M, Coimbra, R, Davies, J, Kirkpatrick, A, Di Carlo, I, Hardcastle, T, Isik, A, Chiarugi, M, Gurusamy, K, Maier, R, Segovia Lohse, H, Jeekel, H, Boermeester, M, Abu-Zidan, F, Inaba, K, Weber, D, Augustin, G, Bonavina, L, Velmahos, G, Sartelli, M, Di Saverio, S, Ten Broek, R, Granieri, S, Dal Mas, F, Fare, C, Peverada, J, Zanghi, S, Vigano, J, Tomasoni, M, Dominioni, T, Cicuttin, E, Hecker, A, Tebala, G, Galante, J, Wani, I, Khokha, V, Sugrue, M, Scalea, T, Tan, E, Malangoni, M, Pararas, N, Podda, M, De Simone, B, Ivatury, R, Cui, Y, Kashuk, J, Peitzman, A, Kim, F, Pikoulis, E, Sganga, G, Chiara, O, Kelly, M, Marzi, I, Picetti, E, Agnoletti, V, De'Angelis, N, Campanelli, G, de Moya, M, Litvin, A, Martinez-Perez, A, Sall, I, Rizoli, S, Tomadze, G, Sakakushev, B, Stahel, P, Civil, I, Shelat, V, Costa, D, Chichom-Mefire, A, Latifi, R, Chirica, M, Amico, F, Pardhan, A, Seenarain, V, Boyapati, N, Hatz, B, Ackermann, T, Abeyasundara, S, Fenton, L, Plani, F, Sarvepalli, R, Rouhbakhshfar, O, Caleo, P, Ho-Ching Yau, V, Clement, K, Christou, E, Castillo, A, Gosal, P, Balasubramaniam, S, Hsu, J, Banphawatanarak, K, Pisano, M, Adriana, T, Michele, A, Cioffi, S, Spota, A, Catena, F, Ansaloni, L, Frassini S., Cobianchi L., Fugazzola P., Biffl W. L., Coccolini F., Damaskos D., Moore E. E., Kluger Y., Ceresoli M., Coimbra R., Davies J., Kirkpatrick A., Di Carlo I., Hardcastle T. C., Isik A., Chiarugi M., Gurusamy K., Maier R. V., Segovia Lohse H. A., Jeekel H., Boermeester M. A., Abu-Zidan F., Inaba K., Weber D. G., Augustin G., Bonavina L., Velmahos G., Sartelli M., Di Saverio S., Ten Broek R. P. G., Granieri S., Dal Mas F., Fare C. N., Peverada J., Zanghi S., Vigano J., Tomasoni M., Dominioni T., Cicuttin E., Hecker A., Tebala G. D., Galante J. M., Wani I., Khokha V., Sugrue M., Scalea T. M., Tan E., Malangoni M. A., Pararas N., Podda M., De Simone B., Ivatury R., Cui Y., Kashuk J., Peitzman A., Kim F., Pikoulis E., Sganga G., Chiara O., Kelly M. D., Marzi I., Picetti E., Agnoletti V., De'Angelis N., Campanelli G., de Moya M., Litvin A., Martinez-Perez A., Sall I., Rizoli S., Tomadze G., Sakakushev B., Stahel P. F., Civil I., Shelat V., Costa D., Chichom-Mefire A., Latifi R., Chirica M., Amico F., Pardhan A., Seenarain V., Boyapati N., Hatz B., Ackermann T., Abeyasundara S., Fenton L., Plani F., Sarvepalli R., Rouhbakhshfar O., Caleo P., Ho-Ching Yau V., Clement K., Christou E., Castillo A. M. G., Gosal P. K. S., Balasubramaniam S., Hsu J., Banphawatanarak K., Pisano M., Adriana T., Michele A., Cioffi S. P. B., Spota A., Catena F., and Ansaloni L.
Abstract: Laparotomy incisions provide easy and rapid access to the peritoneal cavity in case of emergency surgery. Incisional hernia (IH) is a late manifestation of the failure of abdominal wall closure and represents frequent complication of any abdominal incision: IHs can cause pain and discomfort to the patients but also clinical serious sequelae like bowel obstruction, incarceration, strangulation, and necessity of reoperation. Previous guidelines and indications in the literature consider elective settings and evidence about laparotomy closure in emergency settings is lacking. This paper aims to present the World Society of Emergency Surgery (WSES) project called ECLAPTE (Effective Closure of LAParoTomy in Emergency): the final manuscript includes guidelines on the closure of emergency laparotomy.
Published: 2023

4. Fibrinogen in the initial resuscitation of severe trauma (FiiRST): a randomized feasibility trial

Author: Nascimento, B., Callum, J., Tien, H., Peng, H., Rizoli, S., Karanicolas, P., Alam, A., Xiong, W., Selby, R., Garzon, A-M., Colavecchia, C., Howald, R., Nathens, A., and Beckett, A.
Published: 2016
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5. Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Author: Bala, M, Catena, F, Kashuk, J, De Simone, B, Gomes, C, Weber, D, Sartelli, M, Coccolini, F, Kluger, Y, Abu-Zidan, F, Picetti, E, Ansaloni, L, Augustin, G, Biffl, W, Ceresoli, M, Chiara, O, Chiarugi, M, Coimbra, R, Cui, Y, Damaskos, D, Di Saverio, S, Galante, J, Khokha, V, Kirkpatrick, A, Inaba, K, Leppaniemi, A, Litvin, A, Peitzman, A, Shelat, V, Sugrue, M, Tolonen, M, Rizoli, S, Sall, I, Beka, S, Di Carlo, I, Ten Broek, R, Mircea, C, Tebala, G, Pisano, M, van Goor, H, Maier, R, Jeekel, H, Civil, I, Hecker, A, Tan, E, Soreide, K, Lee, M, Wani, I, Bonavina, L, Malangoni, M, Koike, K, Velmahos, G, Fraga, G, Fette, A, De'Angelis, N, Balogh, Z, Scalea, T, Sganga, G, Kelly, M, Khan, J, Stahel, P, Moore, E, Bala M., Catena F., Kashuk J., De Simone B., Gomes C. A., Weber D., Sartelli M., Coccolini F., Kluger Y., Abu-Zidan F. M., Picetti E., Ansaloni L., Augustin G., Biffl W. L., Ceresoli M., Chiara O., Chiarugi M., Coimbra R., Cui Y., Damaskos D., Di Saverio S., Galante J. M., Khokha V., Kirkpatrick A. W., Inaba K., Leppaniemi A., Litvin A., Peitzman A. B., Shelat V. G., Sugrue M., Tolonen M., Rizoli S., Sall I., Beka S. G., Di Carlo I., Ten Broek R., Mircea C., Tebala G., Pisano M., van Goor H., Maier R. V., Jeekel H., Civil I., Hecker A., Tan E., Soreide K., Lee M. J., Wani I., Bonavina L., Malangoni M. A., Koike K., Velmahos G. C., Fraga G. P., Fette A., de'Angelis N., Balogh Z. J., Scalea T. M., Sganga G., Kelly M. D., Khan J., Stahel P. F., Moore E. E., Bala, M, Catena, F, Kashuk, J, De Simone, B, Gomes, C, Weber, D, Sartelli, M, Coccolini, F, Kluger, Y, Abu-Zidan, F, Picetti, E, Ansaloni, L, Augustin, G, Biffl, W, Ceresoli, M, Chiara, O, Chiarugi, M, Coimbra, R, Cui, Y, Damaskos, D, Di Saverio, S, Galante, J, Khokha, V, Kirkpatrick, A, Inaba, K, Leppaniemi, A, Litvin, A, Peitzman, A, Shelat, V, Sugrue, M, Tolonen, M, Rizoli, S, Sall, I, Beka, S, Di Carlo, I, Ten Broek, R, Mircea, C, Tebala, G, Pisano, M, van Goor, H, Maier, R, Jeekel, H, Civil, I, Hecker, A, Tan, E, Soreide, K, Lee, M, Wani, I, Bonavina, L, Malangoni, M, Koike, K, Velmahos, G, Fraga, G, Fette, A, De'Angelis, N, Balogh, Z, Scalea, T, Sganga, G, Kelly, M, Khan, J, Stahel, P, Moore, E, Bala M., Catena F., Kashuk J., De Simone B., Gomes C. A., Weber D., Sartelli M., Coccolini F., Kluger Y., Abu-Zidan F. M., Picetti E., Ansaloni L., Augustin G., Biffl W. L., Ceresoli M., Chiara O., Chiarugi M., Coimbra R., Cui Y., Damaskos D., Di Saverio S., Galante J. M., Khokha V., Kirkpatrick A. W., Inaba K., Leppaniemi A., Litvin A., Peitzman A. B., Shelat V. G., Sugrue M., Tolonen M., Rizoli S., Sall I., Beka S. G., Di Carlo I., Ten Broek R., Mircea C., Tebala G., Pisano M., van Goor H., Maier R. V., Jeekel H., Civil I., Hecker A., Tan E., Soreide K., Lee M. J., Wani I., Bonavina L., Malangoni M. A., Koike K., Velmahos G. C., Fraga G. P., Fette A., de'Angelis N., Balogh Z. J., Scalea T. M., Sganga G., Kelly M. D., Khan J., Stahel P. F., and Moore E. E.
Abstract: Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.
Published: 2022

6. The acute phase management of spinal cord injury affecting polytrauma patients: the ASAP study

Author: Picetti, E, Iaccarino, C, Coimbra, R, Abu-Zidan, F, Tebala, G, Balogh, Z, Biffl, W, Coccolini, F, Gupta, D, Maier, R, Marzi, I, Robba, C, Sartelli, M, Servadei, F, Stahel, P, Taccone, F, Unterberg, A, Antonini, M, Galante, J, Ansaloni, L, Kirkpatrick, A, Rizoli, S, Leppaniemi, A, Chiara, O, De Simone, B, Chirica, M, Shelat, V, Fraga, G, Ceresoli, M, Cattani, L, Minardi, F, Tan, E, Wani, I, Petranca, M, Domenichelli, F, Cui, Y, Malchiodi, L, Sani, E, Litvin, A, Hecker, A, Montanaro, V, Beka, S, Di Saverio, S, Rossi, S, Catena, F, Picetti E., Iaccarino C., Coimbra R., Abu-Zidan F., Tebala G. D., Balogh Z. J., Biffl W. L., Coccolini F., Gupta D., Maier R. V., Marzi I., Robba C., Sartelli M., Servadei F., Stahel P. F., Taccone F. S., Unterberg A. W., Antonini M. V., Galante J. M., Ansaloni L., Kirkpatrick A. W., Rizoli S., Leppaniemi A., Chiara O., De Simone B., Chirica M., Shelat V. G., Fraga G. P., Ceresoli M., Cattani L., Minardi F., Tan E., Wani I., Petranca M., Domenichelli F., Cui Y., Malchiodi L., Sani E., Litvin A., Hecker A., Montanaro V., Beka S. G., Di Saverio S., Rossi S., Catena F., Picetti, E, Iaccarino, C, Coimbra, R, Abu-Zidan, F, Tebala, G, Balogh, Z, Biffl, W, Coccolini, F, Gupta, D, Maier, R, Marzi, I, Robba, C, Sartelli, M, Servadei, F, Stahel, P, Taccone, F, Unterberg, A, Antonini, M, Galante, J, Ansaloni, L, Kirkpatrick, A, Rizoli, S, Leppaniemi, A, Chiara, O, De Simone, B, Chirica, M, Shelat, V, Fraga, G, Ceresoli, M, Cattani, L, Minardi, F, Tan, E, Wani, I, Petranca, M, Domenichelli, F, Cui, Y, Malchiodi, L, Sani, E, Litvin, A, Hecker, A, Montanaro, V, Beka, S, Di Saverio, S, Rossi, S, Catena, F, Picetti E., Iaccarino C., Coimbra R., Abu-Zidan F., Tebala G. D., Balogh Z. J., Biffl W. L., Coccolini F., Gupta D., Maier R. V., Marzi I., Robba C., Sartelli M., Servadei F., Stahel P. F., Taccone F. S., Unterberg A. W., Antonini M. V., Galante J. M., Ansaloni L., Kirkpatrick A. W., Rizoli S., Leppaniemi A., Chiara O., De Simone B., Chirica M., Shelat V. G., Fraga G. P., Ceresoli M., Cattani L., Minardi F., Tan E., Wani I., Petranca M., Domenichelli F., Cui Y., Malchiodi L., Sani E., Litvin A., Hecker A., Montanaro V., Beka S. G., Di Saverio S., Rossi S., and Catena F.
Abstract: Background: Few data on the management of acute phase of traumatic spinal cord injury (tSCI) in patients suffering polytrauma are available. As the therapeutic choices in the first hours may have a deep impact on outcome of tSCI patients, we conducted an international survey investigating this topic. Methods: The survey was composed of 29 items. The main endpoints of the survey were to examine: (1) the hemodynamic and respiratory management, (2) the coagulation management, (3) the timing of magnetic resonance imaging (MRI) and spinal surgery, (4) the use of corticosteroid therapy, (5) the role of intraspinal pressure (ISP)/spinal cord perfusion pressure (SCPP) monitoring and (6) the utilization of therapeutic hypothermia. Results: There were 171 respondents from 139 centers worldwide. A target mean arterial pressure (MAP) target of 80–90 mmHg was chosen in almost half of the cases [n = 84 (49.1%)]. A temporary reduction in the target MAP, for the time strictly necessary to achieve bleeding control in polytrauma, was accepted by most respondents [n = 100 (58.5%)]. Sixty-one respondents (35.7%) considered acceptable a hemoglobin (Hb) level of 7 g/dl in tSCI polytraumatized patients. An arterial partial pressure of oxygen (PaO2) of 80–100 mmHg [n = 94 (55%)] and an arterial partial pressure of carbon dioxide (PaCO2) of 35–40 mmHg [n = 130 (76%)] were chosen in most cases. A little more than half of respondents considered safe a platelet (PLT) count > 100.000/mm3 [n = 99 (57.9%)] and prothrombin time (PT)/activated partial thromboplastin time (aPTT) < 1.5 times the normal control [n = 85 (49.7%)] in patients needing spinal surgery. MRI [n = 160 (93.6%)] and spinal surgery [n = 158 (92.4%)] should be performed after intracranial, hemodynamic, and respiratory stabilization by most respondents. Corticosteroids [n = 103 (60.2%)], ISP/SCPP monitoring [n = 148 (86.5%)], and therapeutic hypothermia [n = 137 (80%)] were not utilized by most respondents. Conclusions: Our s
Published: 2022

7. ECLAPTE: Effective Closure of LAParoTomy in Emergency-2023 World Society of Emergency Surgery guidelines for the closure of laparotomy in emergency settings.

Author: Frassini, S., Cobianchi, L., Fugazzola, P., Biffl, W.L., Coccolini, F., Damaskos, D., Moore, E.E., Kluger, Y., Ceresoli, M., Coimbra, R., Davies, J., Kirkpatrick, A., Carlo, I. Di, Hardcastle, T.C., Isik, A., Chiarugi, M., Gurusamy, K., Maier, R.V., Segovia Lohse, H.A., Jeekel, H., Boermeester, M.A., Abu-Zidan, F., Inaba, K., Weber, D.G., Augustin, G., Bonavina, L., Velmahos, G., Sartelli, M., Saverio, S. Di, Broek, R.P.G ten, Granieri, S., Mas, F. Dal, Farè, C.N., Peverada, J., Zanghì, S., Viganò, J., Tomasoni, M., Dominioni, T., Cicuttin, E., Hecker, A., Tebala, G.D., Galante, J.M., Wani, I., Khokha, V., Sugrue, M., Scalea, T.M., Tan, E.C.T.H., Malangoni, M.A., Pararas, N., Podda, M., Simone, B. De, Ivatury, R., Cui, Y., Kashuk, J., Peitzman, A., Kim, F., Pikoulis, E., Sganga, G., Chiara, O., Kelly, M.D., Marzi, I., Picetti, E., Agnoletti, V., De'Angelis, N., Campanelli, G., Moya, M. de, Litvin, A., Martínez-Pérez, A., Sall, I., Rizoli, S., Tomadze, G., Sakakushev, B., Stahel, P.F., Civil, I., Shelat, V., Costa, D., Chichom-Mefire, A., Latifi, R., Chirica, M., Amico, F., Pardhan, A., Seenarain, V., Boyapati, N., Hatz, B., Ackermann, T., Abeyasundara, S., Fenton, L., Plani, F., Sarvepalli, R., Rouhbakhshfar, O., Caleo, P., Ho-Ching Yau, V., Clement, K., Christou, E., Castillo, A.M.G., Gosal, P.K.S., Balasubramaniam, S., Hsu, J., Banphawatanarak, K., Pisano, M., Adriana, T., Michele, A., Cioffi, S.P.B., Spota, A., Catena, F., Ansaloni, L., Frassini, S., Cobianchi, L., Fugazzola, P., Biffl, W.L., Coccolini, F., Damaskos, D., Moore, E.E., Kluger, Y., Ceresoli, M., Coimbra, R., Davies, J., Kirkpatrick, A., Carlo, I. Di, Hardcastle, T.C., Isik, A., Chiarugi, M., Gurusamy, K., Maier, R.V., Segovia Lohse, H.A., Jeekel, H., Boermeester, M.A., Abu-Zidan, F., Inaba, K., Weber, D.G., Augustin, G., Bonavina, L., Velmahos, G., Sartelli, M., Saverio, S. Di, Broek, R.P.G ten, Granieri, S., Mas, F. Dal, Farè, C.N., Peverada, J., Zanghì, S., Viganò, J., Tomasoni, M., Dominioni, T., Cicuttin, E., Hecker, A., Tebala, G.D., Galante, J.M., Wani, I., Khokha, V., Sugrue, M., Scalea, T.M., Tan, E.C.T.H., Malangoni, M.A., Pararas, N., Podda, M., Simone, B. De, Ivatury, R., Cui, Y., Kashuk, J., Peitzman, A., Kim, F., Pikoulis, E., Sganga, G., Chiara, O., Kelly, M.D., Marzi, I., Picetti, E., Agnoletti, V., De'Angelis, N., Campanelli, G., Moya, M. de, Litvin, A., Martínez-Pérez, A., Sall, I., Rizoli, S., Tomadze, G., Sakakushev, B., Stahel, P.F., Civil, I., Shelat, V., Costa, D., Chichom-Mefire, A., Latifi, R., Chirica, M., Amico, F., Pardhan, A., Seenarain, V., Boyapati, N., Hatz, B., Ackermann, T., Abeyasundara, S., Fenton, L., Plani, F., Sarvepalli, R., Rouhbakhshfar, O., Caleo, P., Ho-Ching Yau, V., Clement, K., Christou, E., Castillo, A.M.G., Gosal, P.K.S., Balasubramaniam, S., Hsu, J., Banphawatanarak, K., Pisano, M., Adriana, T., Michele, A., Cioffi, S.P.B., Spota, A., Catena, F., and Ansaloni, L.
Abstract: Contains fulltext : 296003.pdf (Publisher’s version ) (Open Access), Laparotomy incisions provide easy and rapid access to the peritoneal cavity in case of emergency surgery. Incisional hernia (IH) is a late manifestation of the failure of abdominal wall closure and represents frequent complication of any abdominal incision: IHs can cause pain and discomfort to the patients but also clinical serious sequelae like bowel obstruction, incarceration, strangulation, and necessity of reoperation. Previous guidelines and indications in the literature consider elective settings and evidence about laparotomy closure in emergency settings is lacking. This paper aims to present the World Society of Emergency Surgery (WSES) project called ECLAPTE (Effective Closure of LAParoTomy in Emergency): the final manuscript includes guidelines on the closure of emergency laparotomy.
Published: 2023

8. Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.

Author: Sermonesi, G., Tian, B.W.C.A., Vallicelli, C., Abu-Zidan, F.M., Damaskos, D., Kelly, M.D., Leppäniemi, A., Galante, J.M., Tan, E.C.T.H., Kirkpatrick, A.W., Khokha, V., Romeo, O.M., Chirica, M., Pikoulis, M., Litvin, A., Shelat, V.G., Sakakushev, B., Wani, I., Sall, I., Fugazzola, P., Cicuttin, E., Toro, A., Amico, F., Mas, F.D., Simone, B. De, Sugrue, M., Bonavina, L., Campanelli, G., Carcoforo, P., Cobianchi, L., Coccolini, F., Chiarugi, M., Carlo, I. Di, Saverio, S. Di, Podda, M., Pisano, M., Sartelli, M., Testini, M., Fette, A., Rizoli, S., Picetti, E., Weber, D., Latifi, R., Kluger, Y., Balogh, Z.J., Biffl, W., Jeekel, H., Civil, I., Hecker, A., Ansaloni, L., Bravi, F., Agnoletti, V., Beka, S.G., Moore, E.E., Catena, F., Sermonesi, G., Tian, B.W.C.A., Vallicelli, C., Abu-Zidan, F.M., Damaskos, D., Kelly, M.D., Leppäniemi, A., Galante, J.M., Tan, E.C.T.H., Kirkpatrick, A.W., Khokha, V., Romeo, O.M., Chirica, M., Pikoulis, M., Litvin, A., Shelat, V.G., Sakakushev, B., Wani, I., Sall, I., Fugazzola, P., Cicuttin, E., Toro, A., Amico, F., Mas, F.D., Simone, B. De, Sugrue, M., Bonavina, L., Campanelli, G., Carcoforo, P., Cobianchi, L., Coccolini, F., Chiarugi, M., Carlo, I. Di, Saverio, S. Di, Podda, M., Pisano, M., Sartelli, M., Testini, M., Fette, A., Rizoli, S., Picetti, E., Weber, D., Latifi, R., Kluger, Y., Balogh, Z.J., Biffl, W., Jeekel, H., Civil, I., Hecker, A., Ansaloni, L., Bravi, F., Agnoletti, V., Beka, S.G., Moore, E.E., and Catena, F.
Abstract: Contains fulltext : 300061.pdf (Publisher’s version ) (Open Access), BACKGROUND: Laparoscopy is widely adopted across nearly all surgical subspecialties in the elective setting. Initially finding indication in minor abdominal emergencies, it has gradually become the standard approach in the majority of elective general surgery procedures. Despite many technological advances and increasing acceptance, the laparoscopic approach remains underutilized in emergency general surgery and in abdominal trauma. Emergency laparotomy continues to carry a high morbidity and mortality. In recent years, there has been a growing interest from emergency and trauma surgeons in adopting minimally invasive surgery approaches in the acute surgical setting. The present position paper, supported by the World Society of Emergency Surgery (WSES), aims to provide a review of the literature to reach a consensus on the indications and benefits of a laparoscopic-first approach in patients requiring emergency abdominal surgery for general surgery emergencies or abdominal trauma. METHODS: This position paper was developed according to the WSES methodology. A steering committee performed the literature review and drafted the position paper. An international panel of 54 experts then critically revised the manuscript and discussed it in detail, to develop a consensus on a position statement. RESULTS: A total of 323 studies (systematic review and meta-analysis, randomized clinical trial, retrospective comparative cohort studies, case series) have been selected from an initial pool of 7409 studies. Evidence demonstrates several benefits of the laparoscopic approach in stable patients undergoing emergency abdominal surgery for general surgical emergencies or abdominal trauma. The selection of a stable patient seems to be of paramount importance for a safe adoption of a laparoscopic approach. In hemodynamically stable patients, the laparoscopic approach was found to be safe, feasible and effective as a therapeutic tool or helpful to identify further management steps and n
Published: 2023

9. Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES)

Author: Picetti, E, Catena, F, Abu-Zidan, F, Ansaloni, L, Armonda, R, Bala, M, Balogh, Z, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Cerasti, D, Chesnut, R, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Fainardi, E, Gupta, D, Gurney, J, Hawrylux, G, Helbok, R, Hutchinson, P, Iaccarino, C, Kolias, A, Maier, R, Martin, M, Meyfroidt, G, Okonkwo, D, Rasulo, F, Rizoli, S, Rubiano, A, Sahuquillo, J, Sams, V, Servadei, F, Sharma, D, Shutter, L, Stahel, P, Taccone, F, Udy, A, Zoerle, T, Agnoletti, V, Bravi, F, De Simone, B, Kluger, Y, Martino, C, Moore, E, Sartelli, M, Weber, D, Robba, C, Picetti, Edoardo, Catena, Fausto, Abu-Zidan, Fikri, Ansaloni, Luca, Armonda, Rocco A., Bala, Miklosh, Balogh, Zsolt J., Bertuccio, Alessandro, Biffl, Walt L., Bouzat, Pierre, Buki, Andras, Cerasti, Davide, Chesnut, Randall M., Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Fainardi, Enrico, Gupta, Deepak, Gurney, Jennifer M., Hawrylux, Gregory W. J., Helbok, Raimund, Hutchinson, Peter J. A., Iaccarino, Corrado, Kolias, Angelos, Maier, Ronald W., Martin, Matthew J., Meyfroidt, Geert, Okonkwo, David O., Rasulo, Frank, Rizoli, Sandro, Rubiano, Andres, Sahuquillo, Juan, Sams, Valerie G., Servadei, Franco, Sharma, Deepak, Shutter, Lori, Stahel, Philip F., Taccone, Fabio S., Udy, Andrew, Zoerle, Tommaso, Agnoletti, Vanni, Bravi, Francesca, De Simone, Belinda, Kluger, Yoram, Martino, Costanza, Moore, Ernest E., Sartelli, Massimo, Weber, Dieter, Robba, Chiara, Picetti, E, Catena, F, Abu-Zidan, F, Ansaloni, L, Armonda, R, Bala, M, Balogh, Z, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Cerasti, D, Chesnut, R, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Fainardi, E, Gupta, D, Gurney, J, Hawrylux, G, Helbok, R, Hutchinson, P, Iaccarino, C, Kolias, A, Maier, R, Martin, M, Meyfroidt, G, Okonkwo, D, Rasulo, F, Rizoli, S, Rubiano, A, Sahuquillo, J, Sams, V, Servadei, F, Sharma, D, Shutter, L, Stahel, P, Taccone, F, Udy, A, Zoerle, T, Agnoletti, V, Bravi, F, De Simone, B, Kluger, Y, Martino, C, Moore, E, Sartelli, M, Weber, D, Robba, C, Picetti, Edoardo, Catena, Fausto, Abu-Zidan, Fikri, Ansaloni, Luca, Armonda, Rocco A., Bala, Miklosh, Balogh, Zsolt J., Bertuccio, Alessandro, Biffl, Walt L., Bouzat, Pierre, Buki, Andras, Cerasti, Davide, Chesnut, Randall M., Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Fainardi, Enrico, Gupta, Deepak, Gurney, Jennifer M., Hawrylux, Gregory W. J., Helbok, Raimund, Hutchinson, Peter J. A., Iaccarino, Corrado, Kolias, Angelos, Maier, Ronald W., Martin, Matthew J., Meyfroidt, Geert, Okonkwo, David O., Rasulo, Frank, Rizoli, Sandro, Rubiano, Andres, Sahuquillo, Juan, Sams, Valerie G., Servadei, Franco, Sharma, Deepak, Shutter, Lori, Stahel, Philip F., Taccone, Fabio S., Udy, Andrew, Zoerle, Tommaso, Agnoletti, Vanni, Bravi, Francesca, De Simone, Belinda, Kluger, Yoram, Martino, Costanza, Moore, Ernest E., Sartelli, Massimo, Weber, Dieter, and Robba, Chiara
Abstract: Background: Severe traumatic brain-injured (TBI) patients should be primarily admitted to a hub trauma center (hospital with neurosurgical capabilities) to allow immediate delivery of appropriate care in a specialized environment. Sometimes, severe TBI patients are admitted to a spoke hospital (hospital without neurosurgical capabilities), and scarce data are available regarding the optimal management of severe isolated TBI patients who do not have immediate access to neurosurgical care. Methods: A multidisciplinary consensus panel composed of 41 physicians selected for their established clinical and scientific expertise in the acute management of TBI patients with different specializations (anesthesia/intensive care, neurocritical care, acute care surgery, neurosurgery and neuroradiology) was established. The consensus was endorsed by the World Society of Emergency Surgery, and a modified Delphi approach was adopted. Results: A total of 28 statements were proposed and discussed. Consensus was reached on 22 strong recommendations and 3 weak recommendations. In three cases, where consensus was not reached, no recommendation was provided. Conclusions: This consensus provides practical recommendations to support clinician’s decision making in the management of isolated severe TBI patients in centers without neurosurgical capabilities and during transfer to a hub center.
Published: 2023

10. Correction: Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES)

Author: Picetti, Edoardo, Picetti, E, Catena, F, Abu-Zidan, F, Ansaloni, L, Armonda, R, Bala, M, Balogh, Z, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Cerasti, D, Chesnut, R, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Fainardi, E, Gupta, D, Gurney, J, Hawryluk, G, Helbok, R, Hutchinson, P, Iaccarino, C, Kolias, A, Maier, R, Martin, M, Meyfroidt, G, Okonkwo, D, Rasulo, F, Rizoli, S, Rubiano, A, Sahuquillo, J, Sams, V, Servadei, F, Sharma, D, Shutter, L, Stahel, P, Taccone, F, Udy, A, Zoerle, T, Agnoletti, V, Bravi, F, De Simone, B, Kluger, Y, Martino, C, Moore, E, Sartelli, M, Weber, D, Robba, C, Picetti, Edoardo, Catena, Fausto, Abu-Zidan, Fikri, Ansaloni, Luca, Armonda, Rocco A, Bala, Miklosh, Balogh, Zsolt J, Bertuccio, Alessandro, Biffl, Walt L, Bouzat, Pierre, Buki, Andras, Cerasti, Davide, Chesnut, Randall M, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Fainardi, Enrico, Gupta, Deepak, Gurney, Jennifer M, Hawryluk, Gregory W J, Helbok, Raimund, Hutchinson, Peter J A, Iaccarino, Corrado, Kolias, Angelos, Maier, Ronald W, Martin, Matthew J, Meyfroidt, Geert, Okonkwo, David O, Rasulo, Frank, Rizoli, Sandro, Rubiano, Andres, Sahuquillo, Juan, Sams, Valerie G, Servadei, Franco, Sharma, Deepak, Shutter, Lori, Stahel, Philip F, Taccone, Fabio S, Udy, Andrew, Zoerle, Tommaso, Agnoletti, Vanni, Bravi, Francesca, De Simone, Belinda, Kluger, Yoram, Martino, Costanza, Moore, Ernest E, Sartelli, Massimo, Weber, Dieter, Robba, Chiara, Picetti, Edoardo, Picetti, E, Catena, F, Abu-Zidan, F, Ansaloni, L, Armonda, R, Bala, M, Balogh, Z, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Cerasti, D, Chesnut, R, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Fainardi, E, Gupta, D, Gurney, J, Hawryluk, G, Helbok, R, Hutchinson, P, Iaccarino, C, Kolias, A, Maier, R, Martin, M, Meyfroidt, G, Okonkwo, D, Rasulo, F, Rizoli, S, Rubiano, A, Sahuquillo, J, Sams, V, Servadei, F, Sharma, D, Shutter, L, Stahel, P, Taccone, F, Udy, A, Zoerle, T, Agnoletti, V, Bravi, F, De Simone, B, Kluger, Y, Martino, C, Moore, E, Sartelli, M, Weber, D, Robba, C, Picetti, Edoardo, Catena, Fausto, Abu-Zidan, Fikri, Ansaloni, Luca, Armonda, Rocco A, Bala, Miklosh, Balogh, Zsolt J, Bertuccio, Alessandro, Biffl, Walt L, Bouzat, Pierre, Buki, Andras, Cerasti, Davide, Chesnut, Randall M, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Fainardi, Enrico, Gupta, Deepak, Gurney, Jennifer M, Hawryluk, Gregory W J, Helbok, Raimund, Hutchinson, Peter J A, Iaccarino, Corrado, Kolias, Angelos, Maier, Ronald W, Martin, Matthew J, Meyfroidt, Geert, Okonkwo, David O, Rasulo, Frank, Rizoli, Sandro, Rubiano, Andres, Sahuquillo, Juan, Sams, Valerie G, Servadei, Franco, Sharma, Deepak, Shutter, Lori, Stahel, Philip F, Taccone, Fabio S, Udy, Andrew, Zoerle, Tommaso, Agnoletti, Vanni, Bravi, Francesca, De Simone, Belinda, Kluger, Yoram, Martino, Costanza, Moore, Ernest E, Sartelli, Massimo, Weber, Dieter, and Robba, Chiara
Published: 2023

11. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy

Author: De'Angelis, N, Catena, F, Memeo, R, Coccolini, F, Martinez-Perez, A, Romeo, O, De Simone, B, Di Saverio, S, Brustia, R, Rhaiem, R, Piardi, T, Conticchio, M, Marchegiani, F, Beghdadi, N, Abu-Zidan, F, Alikhanov, R, Allard, M, Allievi, N, Amaddeo, G, Ansaloni, L, Andersson, R, Andolfi, E, Azfar, M, Bala, M, Benkabbou, A, Ben-Ishay, O, Bianchi, G, Biffl, W, Brunetti, F, Carra, M, Casanova, D, Celentano, V, Ceresoli, M, Chiara, O, Cimbanassi, S, Bini, R, Coimbra, R, Luigi de'Angelis, G, Decembrino, F, De Palma, A, de Reuver, P, Domingo, C, Cotsoglou, C, Ferrero, A, Fraga, G, Gaiani, F, Gheza, F, Gurrado, A, Harrison, E, Henriquez, A, Hofmeyr, S, Iadarola, R, Kashuk, J, Kianmanesh, R, Kirkpatrick, A, Kluger, Y, Landi, F, Langella, S, Lapointe, R, Le Roy, B, Luciani, A, Machado, F, Maggi, U, Maier, R, Mefire, A, Hiramatsu, K, Ordonez, C, Patrizi, F, Planells, M, Peitzman, A, Pekolj, J, Perdigao, F, Pereira, B, Pessaux, P, Pisano, M, Puyana, J, Rizoli, S, Portigliotti, L, Romito, R, Sakakushev, B, Sanei, B, Scatton, O, Serradilla-Martin, M, Schneck, A, Sissoko, M, Sobhani, I, ten Broek, R, Testini, M, Valinas, R, Veloudis, G, Vitali, G, Weber, D, Zorcolo, L, Giuliante, F, Gavriilidis, P, Fuks, D, Sommacale, D, de'Angelis N., Catena F., Memeo R., Coccolini F., Martinez-Perez A., Romeo O. M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., Piardi T., Conticchio M., Marchegiani F., Beghdadi N., Abu-Zidan F. M., Alikhanov R., Allard M. -A., Allievi N., Amaddeo G., Ansaloni L., Andersson R., Andolfi E., Azfar M., Bala M., Benkabbou A., Ben-Ishay O., Bianchi G., Biffl W. L., Brunetti F., Carra M. C., Casanova D., Celentano V., Ceresoli M., Chiara O., Cimbanassi S., Bini R., Coimbra R., Luigi de'Angelis G., Decembrino F., De Palma A., de Reuver P. R., Domingo C., Cotsoglou C., Ferrero A., Fraga G. P., Gaiani F., Gheza F., Gurrado A., Harrison E., Henriquez A., Hofmeyr S., Iadarola R., Kashuk J. L., Kianmanesh R., Kirkpatrick A. W., Kluger Y., Landi F., Langella S., Lapointe R., Le Roy B., Luciani A., Machado F., Maggi U., Maier R. V., Mefire A. C., Hiramatsu K., Ordonez C., Patrizi F., Planells M., Peitzman A. B., Pekolj J., Perdigao F., Pereira B. M., Pessaux P., Pisano M., Puyana J. C., Rizoli S., Portigliotti L., Romito R., Sakakushev B., Sanei B., Scatton O., Serradilla-Martin M., Schneck A. -S., Sissoko M. L., Sobhani I., ten Broek R. P., Testini M., Valinas R., Veloudis G., Vitali G. C., Weber D., Zorcolo L., Giuliante F., Gavriilidis P., Fuks D., Sommacale D., De'Angelis, N, Catena, F, Memeo, R, Coccolini, F, Martinez-Perez, A, Romeo, O, De Simone, B, Di Saverio, S, Brustia, R, Rhaiem, R, Piardi, T, Conticchio, M, Marchegiani, F, Beghdadi, N, Abu-Zidan, F, Alikhanov, R, Allard, M, Allievi, N, Amaddeo, G, Ansaloni, L, Andersson, R, Andolfi, E, Azfar, M, Bala, M, Benkabbou, A, Ben-Ishay, O, Bianchi, G, Biffl, W, Brunetti, F, Carra, M, Casanova, D, Celentano, V, Ceresoli, M, Chiara, O, Cimbanassi, S, Bini, R, Coimbra, R, Luigi de'Angelis, G, Decembrino, F, De Palma, A, de Reuver, P, Domingo, C, Cotsoglou, C, Ferrero, A, Fraga, G, Gaiani, F, Gheza, F, Gurrado, A, Harrison, E, Henriquez, A, Hofmeyr, S, Iadarola, R, Kashuk, J, Kianmanesh, R, Kirkpatrick, A, Kluger, Y, Landi, F, Langella, S, Lapointe, R, Le Roy, B, Luciani, A, Machado, F, Maggi, U, Maier, R, Mefire, A, Hiramatsu, K, Ordonez, C, Patrizi, F, Planells, M, Peitzman, A, Pekolj, J, Perdigao, F, Pereira, B, Pessaux, P, Pisano, M, Puyana, J, Rizoli, S, Portigliotti, L, Romito, R, Sakakushev, B, Sanei, B, Scatton, O, Serradilla-Martin, M, Schneck, A, Sissoko, M, Sobhani, I, ten Broek, R, Testini, M, Valinas, R, Veloudis, G, Vitali, G, Weber, D, Zorcolo, L, Giuliante, F, Gavriilidis, P, Fuks, D, Sommacale, D, de'Angelis N., Catena F., Memeo R., Coccolini F., Martinez-Perez A., Romeo O. M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., Piardi T., Conticchio M., Marchegiani F., Beghdadi N., Abu-Zidan F. M., Alikhanov R., Allard M. -A., Allievi N., Amaddeo G., Ansaloni L., Andersson R., Andolfi E., Azfar M., Bala M., Benkabbou A., Ben-Ishay O., Bianchi G., Biffl W. L., Brunetti F., Carra M. C., Casanova D., Celentano V., Ceresoli M., Chiara O., Cimbanassi S., Bini R., Coimbra R., Luigi de'Angelis G., Decembrino F., De Palma A., de Reuver P. R., Domingo C., Cotsoglou C., Ferrero A., Fraga G. P., Gaiani F., Gheza F., Gurrado A., Harrison E., Henriquez A., Hofmeyr S., Iadarola R., Kashuk J. L., Kianmanesh R., Kirkpatrick A. W., Kluger Y., Landi F., Langella S., Lapointe R., Le Roy B., Luciani A., Machado F., Maggi U., Maier R. V., Mefire A. C., Hiramatsu K., Ordonez C., Patrizi F., Planells M., Peitzman A. B., Pekolj J., Perdigao F., Pereira B. M., Pessaux P., Pisano M., Puyana J. C., Rizoli S., Portigliotti L., Romito R., Sakakushev B., Sanei B., Scatton O., Serradilla-Martin M., Schneck A. -S., Sissoko M. L., Sobhani I., ten Broek R. P., Testini M., Valinas R., Veloudis G., Vitali G. C., Weber D., Zorcolo L., Giuliante F., Gavriilidis P., Fuks D., and Sommacale D.
Abstract: Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4–1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
Published: 2021

12. ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016

Author: Velasquez, T., Mackey, G., Lusk, J., Kyle, U. G., Fontenot, T., Marshall, P., Shekerdemian, L. S., Coss-Bu, J. A., Nishigaki, A., Yatabe, T., Tamura, T., Yamashita, K., Yokoyama, M., Ruiz-Rodriguez, J. C., Encina, B., Belmonte, R., Troncoso, I., Tormos, P., Riveiro, M., Baena, J., Sanchez, A., Bañeras, J., Cordón, J., Duran, N., Ruiz, A., Caballero, J., Nuvials, X., Riera, J., Serra, J., Rutten, A. M. F., van Ieperen, S. N. M., Der Kinderen, E. P. H. M., Van Logten, T., Kovacikova, L., Skrak, P., Zahorec, M., Kyle, U. G., Akcan-Arikan, A., Silva, J. C., Mackey, G., Lusk, J., Goldsworthy, M., Shekerdemian, L. S., Coss-Bu, J. A., Wood, D., Harrison, D., Parslow, R., Davis, P., Pappachan, J., Goodwin, S., Ramnarayan, P., Chernyshuk, S., Yemets, H., Zhovnir, V., Pulitano’, S. M., De Rosa, S., Mancino, A., Villa, G., Tosi, F., Franchi, P., Conti, G., Patel, B., Khine, H., Shah, A., Sung, D., Singer, L., Haghbin, S., Inaloo, S., Serati, Z., Idei, M., Nomura, T., Yamamoto, N., Sakai, Y., Yoshida, T., Matsuda, Y., Yamaguchi, Y., Takaki, S., Yamaguchi, O., Goto, T., Longani, N., Medar, S., Abdel-Aal, I. R., El Adawy, A. S., Mohammed, H. M. E. H., Mohamed, A. N., Parry, S. M., Knight, L. D., Denehy, L., De Morton, N., Baldwin, C. E., Sani, D., Kayambu, G., da Silva, V. Z. M., Phongpagdi, P., Puthucheary, Z. A., Granger, C. L., Rydingsward, J. E., Horkan, C. M., Christopher, K. B., McWilliams, D., Jones, C., Reeves, E., Atkins, G., Snelson, C., Aitken, L. M., Rattray, J., Kenardy, J., Hull, A. M., Ullman, A., Le Brocque, R., Mitchell, M., Davis, C., Macfarlane, B., Azevedo, J. C., Rocha, L. L., De Freitas, F. F. M., Cavalheiro, A. M., Lucinio, N. M., Lobato, M. S., Ebeling, G., Kraegpoeth, A., Laerkner, E., De Brito-Ashurst, I., White, C., Gregory, S., Forni, L. G., Flowers, E., Curtis, A., Wood, C. A., Siu, K., Venkatesan, K., Muhammad, J. B. H., Ng, L., Seet, E., Baptista, N., Escoval, A., Tomas, E., Agrawal, R., Mathew, R., Varma, A., Dima, E., Charitidou, E., Perivolioti, E., Pratikaki, M., Vrettou, C., Giannopoulos, A., Zakynthinos, S., Routsi, C., Atchade, E., Houzé, S., Jean-Baptiste, S., Thabut, G., Genève, C., Tanaka, S., Lortat-Jacob, B., Augustin, P., Desmard, M., Montravers, P., de Molina, F. J. González, Barbadillo, S., Alejandro, R., Álvarez-Lerma, F., Vallés, J., Catalán, R. M., Palencia, E., Jareño, A., Granada, R. M., Ignacio, M. 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J., Gonzalez, C. A., Pinto, J. L., Orozco, V., Patiño, J. A., Garcia, P. K., Contreras, K. M., Rodriguez, P., Echeverri, J. E., GETGAG Working Group, JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group, CAPCRI Study, for the ReVA Research Network and the PROVE Network Investigators, from the FROG ICU Investigators, The WIND study group, Plug Working Group, GETGAG/SEMICYUC, AKI Research Group, St George’s University of London, IPREA Study Group, FINNRESUSCI Study Group, PICS- HCPA: Programa Intrahospitalar de Combate à Sepse do Hospital de Clínicas de Porto Alegre, ENVIN-HELICS Study Group, ARIAM registry of adult cardiac surgery, The Rapid Diagnosis of Infections in the Critically Ill Team, Tokyo Womens Medical University, PLUG working group, PLUG Working Group, On behalf of Okayama Research Investigation Organizing Network (ORION)investigators, PS-ICU Group, Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group, Student Research Committee - Shiraz University of Medical Sciences, ARIAM-ANDALUCIA, The WIND study group, PLUG Working Group, The WIND study group, PLUG Working Group, and Plug working group
Published: 2016
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13. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines

Author: Di Saverio, S, Podda, M, De Simone, B, Ceresoli, M, Augustin, G, Gori, A, Boermeester, M, Sartelli, M, Coccolini, F, Tarasconi, A, De' Angelis, N, Weber, D, Tolonen, M, Birindelli, A, Biffl, W, Moore, E, Kelly, M, Soreide, K, Kashuk, J, Ten Broek, R, Gomes, C, Sugrue, M, Davies, R, Damaskos, D, Leppaniemi, A, Kirkpatrick, A, Peitzman, A, Fraga, G, Maier, R, Coimbra, R, Chiarugi, M, Sganga, G, Pisanu, A, De' Angelis, G, Tan, E, Van Goor, H, Pata, F, Di Carlo, I, Chiara, O, Litvin, A, Campanile, F, Sakakushev, B, Tomadze, G, Demetrashvili, Z, Latifi, R, Abu-Zidan, F, Romeo, O, Segovia-Lohse, H, Baiocchi, G, Costa, D, Rizoli, S, Balogh, Z, Bendinelli, C, Scalea, T, Ivatury, R, Velmahos, G, Andersson, R, Kluger, Y, Ansaloni, L, Catena, F, Di Saverio S., Podda M., De Simone B., Ceresoli M., Augustin G., Gori A., Boermeester M., Sartelli M., Coccolini F., Tarasconi A., De' Angelis N., Weber D. G., Tolonen M., Birindelli A., Biffl W., Moore E. E., Kelly M., Soreide K., Kashuk J., Ten Broek R., Gomes C. A., Sugrue M., Davies R. J., Damaskos D., Leppaniemi A., Kirkpatrick A., Peitzman A. B., Fraga G. P., Maier R. V., Coimbra R., Chiarugi M., Sganga G., Pisanu A., De' Angelis G. L., Tan E., Van Goor H., Pata F., Di Carlo I., Chiara O., Litvin A., Campanile F. C., Sakakushev B., Tomadze G., Demetrashvili Z., Latifi R., Abu-Zidan F., Romeo O., Segovia-Lohse H., Baiocchi G., Costa D., Rizoli S., Balogh Z. J., Bendinelli C., Scalea T., Ivatury R., Velmahos G., Andersson R., Kluger Y., Ansaloni L., Catena F., Di Saverio, S, Podda, M, De Simone, B, Ceresoli, M, Augustin, G, Gori, A, Boermeester, M, Sartelli, M, Coccolini, F, Tarasconi, A, De' Angelis, N, Weber, D, Tolonen, M, Birindelli, A, Biffl, W, Moore, E, Kelly, M, Soreide, K, Kashuk, J, Ten Broek, R, Gomes, C, Sugrue, M, Davies, R, Damaskos, D, Leppaniemi, A, Kirkpatrick, A, Peitzman, A, Fraga, G, Maier, R, Coimbra, R, Chiarugi, M, Sganga, G, Pisanu, A, De' Angelis, G, Tan, E, Van Goor, H, Pata, F, Di Carlo, I, Chiara, O, Litvin, A, Campanile, F, Sakakushev, B, Tomadze, G, Demetrashvili, Z, Latifi, R, Abu-Zidan, F, Romeo, O, Segovia-Lohse, H, Baiocchi, G, Costa, D, Rizoli, S, Balogh, Z, Bendinelli, C, Scalea, T, Ivatury, R, Velmahos, G, Andersson, R, Kluger, Y, Ansaloni, L, Catena, F, Di Saverio S., Podda M., De Simone B., Ceresoli M., Augustin G., Gori A., Boermeester M., Sartelli M., Coccolini F., Tarasconi A., De' Angelis N., Weber D. G., Tolonen M., Birindelli A., Biffl W., Moore E. E., Kelly M., Soreide K., Kashuk J., Ten Broek R., Gomes C. A., Sugrue M., Davies R. J., Damaskos D., Leppaniemi A., Kirkpatrick A., Peitzman A. B., Fraga G. P., Maier R. V., Coimbra R., Chiarugi M., Sganga G., Pisanu A., De' Angelis G. L., Tan E., Van Goor H., Pata F., Di Carlo I., Chiara O., Litvin A., Campanile F. C., Sakakushev B., Tomadze G., Demetrashvili Z., Latifi R., Abu-Zidan F., Romeo O., Segovia-Lohse H., Baiocchi G., Costa D., Rizoli S., Balogh Z. J., Bendinelli C., Scalea T., Ivatury R., Velmahos G., Andersson R., Kluger Y., Ansaloni L., and Catena F.
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: Use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospi
Published: 2020

14. The Immunological Effects of Hypertonic Saline

Author: Rizoli, S. B., Rotstein, O. D., Sibbald, W. J., and Vincent, Jean-Louis, editor
Published: 2002
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15. Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Author: Bala, M., Catena, F., Kashuk, J., Simone, B. De, Gomes, C.A., Weber, D., Sartelli, M., Coccolini, F., Kluger, Y., Abu-Zidan, F.M., Picetti, E., Ansaloni, L., Augustin, G., Biffl, W.L., Ceresoli, M., Chiara, O., Chiarugi, M., Coimbra, R., Cui, Y., Damaskos, D., Saverio, S. Di, Galante, J.M., Khokha, V., Kirkpatrick, A.W., Inaba, K., Leppäniemi, A., Litvin, A., Peitzman, A.B., Shelat, V.G., Sugrue, M., Tolonen, M., Rizoli, S., Sall, I., Beka, S.G., Carlo, I. Di, Broek, R.P.G ten, Mircea, C., Tebala, G., Pisano, M., Goor, H. van, Maier, R.V., Jeekel, H., Civil, I., Hecker, A., Tan, E.C.T.H., Soreide, K., Lee, M.J., Wani, I., Bonavina, L., Malangoni, M.A., Koike, Kaoru, Velmahos, G.C., Fraga, G.P., Fette, A., De'Angelis, N., Balogh, Z.J., Scalea, T.M., Sganga, G., Kelly, M.D., Khan, J., Stahel, P.F., Moore, E.E., Bala, M., Catena, F., Kashuk, J., Simone, B. De, Gomes, C.A., Weber, D., Sartelli, M., Coccolini, F., Kluger, Y., Abu-Zidan, F.M., Picetti, E., Ansaloni, L., Augustin, G., Biffl, W.L., Ceresoli, M., Chiara, O., Chiarugi, M., Coimbra, R., Cui, Y., Damaskos, D., Saverio, S. Di, Galante, J.M., Khokha, V., Kirkpatrick, A.W., Inaba, K., Leppäniemi, A., Litvin, A., Peitzman, A.B., Shelat, V.G., Sugrue, M., Tolonen, M., Rizoli, S., Sall, I., Beka, S.G., Carlo, I. Di, Broek, R.P.G ten, Mircea, C., Tebala, G., Pisano, M., Goor, H. van, Maier, R.V., Jeekel, H., Civil, I., Hecker, A., Tan, E.C.T.H., Soreide, K., Lee, M.J., Wani, I., Bonavina, L., Malangoni, M.A., Koike, Kaoru, Velmahos, G.C., Fraga, G.P., Fette, A., De'Angelis, N., Balogh, Z.J., Scalea, T.M., Sganga, G., Kelly, M.D., Khan, J., Stahel, P.F., and Moore, E.E.
Abstract: Item does not contain fulltext, Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09-0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.
Published: 2022

16. Frühe viskoelastizitätsbasierte Gerinnungstherapie bei blutenden Schwerverletzten: Bericht der Konsensusgruppe über die Konsensuskonferenz 2014 zur Erarbeitung einer S2k-Leitlinie

Author: Maegele, M., Inaba, K., Rizoli, S., Veigas, P., Callum, J., Davenport, R., Fröhlich, M., Hess, J., and Konsensusgruppe zur Erarbeitung einer viskoelastizitätsbasierten Leitlinie zur frühen Gerinnungstherapie bei blutenden Schwerverletzten
Published: 2015
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17. Kidney and uro-trauma: WSES-AAST guidelines

Author: Coccolini, F, Moore, E, Kluger, Y, Biffl, W, Leppaniemi, A, Matsumura, Y, Kim, F, Peitzman, A, Fraga, G, Sartelli, M, Ansaloni, L, Augustin, G, Kirkpatrick, A, Abu-Zidan, F, Wani, I, Weber, D, Pikoulis, E, Larrea, M, Arvieux, C, Manchev, V, Reva, V, Coimbra, R, Khokha, V, Mefire, A, Ordonez, C, Chiarugi, M, Machado, F, Sakakushev, B, Matsumoto, J, Maier, R, Di Carlo, I, Catena, F, Fugazzola, P, Stommel, M, Rajashekar, M, Tan, E, Tolonen, M, Ceresoli, M, Gomez, C, Allievi, N, Chirica, M, Salvetti, F, Bertelli, R, Ben-Ishay, O, Bahouth, H, Baiocchi, G, Tarasconi, A, Cimbanassi, S, Chiara, O, Ten-Broek, R, Montori, G, Picariello, E, Solaini, L, Hecker, A, Tomasoni, M, Perfetti, P, Parry, N, Deangelis, N, Pereira, B, Bado, J, Romeo, O, Pikoulis, A, Bala, M, Napolitano, L, Galante, J, Rizoli, S, Ferrada, P, Horer, T, Brenner, M, Ivatury, R, Coccolini F., Moore E. E., Kluger Y., Biffl W., Leppaniemi A., Matsumura Y., Kim F., Peitzman A. B., Fraga G. P., Sartelli M., Ansaloni L., Augustin G., Kirkpatrick A., Abu-Zidan F., Wani I., Weber D., Pikoulis E., Larrea M., Arvieux C., Manchev V., Reva V., Coimbra R., Khokha V., Mefire A. C., Ordonez C., Chiarugi M., Machado F., Sakakushev B., Matsumoto J., Maier R., Di Carlo I., Catena F., Fugazzola P., Stommel M., Rajashekar M., Tan E., Tolonen M., Ceresoli M., Gomez C. A., Allievi N., Chirica M., Salvetti F., Bertelli R., Ben-Ishay O., Bahouth H., Baiocchi G., Tarasconi A., Cimbanassi S., Chiara O., Ten-Broek R., Montori G., Picariello E., Solaini L., Hecker A., Tomasoni M., Perfetti P., Parry N., Deangelis N., Pereira B. M., Bado J., Romeo O., Pikoulis A., Bala M., Napolitano L., Galante J., Rizoli S., Ferrada P., Horer T., Brenner M., Ivatury R., Coccolini, F, Moore, E, Kluger, Y, Biffl, W, Leppaniemi, A, Matsumura, Y, Kim, F, Peitzman, A, Fraga, G, Sartelli, M, Ansaloni, L, Augustin, G, Kirkpatrick, A, Abu-Zidan, F, Wani, I, Weber, D, Pikoulis, E, Larrea, M, Arvieux, C, Manchev, V, Reva, V, Coimbra, R, Khokha, V, Mefire, A, Ordonez, C, Chiarugi, M, Machado, F, Sakakushev, B, Matsumoto, J, Maier, R, Di Carlo, I, Catena, F, Fugazzola, P, Stommel, M, Rajashekar, M, Tan, E, Tolonen, M, Ceresoli, M, Gomez, C, Allievi, N, Chirica, M, Salvetti, F, Bertelli, R, Ben-Ishay, O, Bahouth, H, Baiocchi, G, Tarasconi, A, Cimbanassi, S, Chiara, O, Ten-Broek, R, Montori, G, Picariello, E, Solaini, L, Hecker, A, Tomasoni, M, Perfetti, P, Parry, N, Deangelis, N, Pereira, B, Bado, J, Romeo, O, Pikoulis, A, Bala, M, Napolitano, L, Galante, J, Rizoli, S, Ferrada, P, Horer, T, Brenner, M, Ivatury, R, Coccolini F., Moore E. E., Kluger Y., Biffl W., Leppaniemi A., Matsumura Y., Kim F., Peitzman A. B., Fraga G. P., Sartelli M., Ansaloni L., Augustin G., Kirkpatrick A., Abu-Zidan F., Wani I., Weber D., Pikoulis E., Larrea M., Arvieux C., Manchev V., Reva V., Coimbra R., Khokha V., Mefire A. C., Ordonez C., Chiarugi M., Machado F., Sakakushev B., Matsumoto J., Maier R., Di Carlo I., Catena F., Fugazzola P., Stommel M., Rajashekar M., Tan E., Tolonen M., Ceresoli M., Gomez C. A., Allievi N., Chirica M., Salvetti F., Bertelli R., Ben-Ishay O., Bahouth H., Baiocchi G., Tarasconi A., Cimbanassi S., Chiara O., Ten-Broek R., Montori G., Picariello E., Solaini L., Hecker A., Tomasoni M., Perfetti P., Parry N., Deangelis N., Pereira B. M., Bado J., Romeo O., Pikoulis A., Bala M., Napolitano L., Galante J., Rizoli S., Ferrada P., Horer T., Brenner M., and Ivatury R.
Abstract: Renal and urogenital injuries occur in approximately 10-20% of abdominal trauma in adults and children. Optimal management should take into consideration the anatomic injury, the hemodynamic status, and the associated injuries. The management of urogenital trauma aims to restore homeostasis and normal physiology especially in pediatric patients where non-operative management is considered the gold standard. As with all traumatic conditions, the management of urogenital trauma should be multidisciplinary including urologists, interventional radiologists, and trauma surgeons, as well as emergency and ICU physicians. The aim of this paper is to present the World Society of Emergency Surgery (WSES) and the American Association for the Surgery of Trauma (AAST) kidney and urogenital trauma management guidelines.
Published: 2019

18. Is delaying pharmacological thromboprophylaxis associated with thromboembolic complications?

Author: Padim, P, Alshafai, A, Canestrini, S, Rizoli, S, De Rezende Neto, J, and McFarlan, A
Published: 2015
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19. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy

Author: De'Angelis, N., Catena, F., Memeo, R., Coccolini, F., Martínez-Pérez, A., Romeo, O.M., Simone, B. De, Saverio, S. Di, Brustia, R., Rhaiem, R., Piardi, T., Conticchio, M., Marchegiani, F., Beghdadi, N., Abu-Zidan, F.M., Alikhanov, R., Allard, M.A., Allievi, N., Amaddeo, G., Ansaloni, L., Andersson, R., Andolfi, E., Azfar, M., Bala, M., Benkabbou, A., Ben-Ishay, O., Bianchi, G., Biffl, W.L., Brunetti, F., Carra, M.C., Casanova, D., Celentano, V., Ceresoli, M., Chiara, O., Cimbanassi, S., Bini, R., Coimbra, R., de'Angelis, G. Luigi, Decembrino, F., Palma, A., Reuver, P.R. de, Domingo, C., Cotsoglou, C., Ferrero, A., Fraga, G.P., Gaiani, F., Gheza, F., Gurrado, A., Harrison, E., Henriquez, A., Hofmeyr, S., Iadarola, R., Kashuk, J.L., Kianmanesh, R., Kirkpatrick, A.W., Kluger, Y., Landi, F., Langella, S., Lapointe, R., Roy, B., Luciani, A., Machado, F., Maggi, U., Maier, R.V., Mefire, A.C., Hiramatsu, K., Ordoñez, C., Patrizi, F., Planells, M., Peitzman, A.B., Pekolj, J., Perdigao, F., Pereira, B.M., Pessaux, P., Pisano, M., Puyana, J.C., Rizoli, S., Portigliotti, L., Romito, R., Sakakushev, B., Sanei, B., Scatton, O., Serradilla-Martin, M., Schneck, A.S., Sissoko, M.L., Sobhani, I., Broek, R.P. Ten, Testini, M., Valinas, R., Veloudis, G., Vitali, G.C., Weber, D., Zorcolo, L., Giuliante, F., Gavriilidis, P., Fuks, D., Sommacale, D., De'Angelis, N., Catena, F., Memeo, R., Coccolini, F., Martínez-Pérez, A., Romeo, O.M., Simone, B. De, Saverio, S. Di, Brustia, R., Rhaiem, R., Piardi, T., Conticchio, M., Marchegiani, F., Beghdadi, N., Abu-Zidan, F.M., Alikhanov, R., Allard, M.A., Allievi, N., Amaddeo, G., Ansaloni, L., Andersson, R., Andolfi, E., Azfar, M., Bala, M., Benkabbou, A., Ben-Ishay, O., Bianchi, G., Biffl, W.L., Brunetti, F., Carra, M.C., Casanova, D., Celentano, V., Ceresoli, M., Chiara, O., Cimbanassi, S., Bini, R., Coimbra, R., de'Angelis, G. Luigi, Decembrino, F., Palma, A., Reuver, P.R. de, Domingo, C., Cotsoglou, C., Ferrero, A., Fraga, G.P., Gaiani, F., Gheza, F., Gurrado, A., Harrison, E., Henriquez, A., Hofmeyr, S., Iadarola, R., Kashuk, J.L., Kianmanesh, R., Kirkpatrick, A.W., Kluger, Y., Landi, F., Langella, S., Lapointe, R., Roy, B., Luciani, A., Machado, F., Maggi, U., Maier, R.V., Mefire, A.C., Hiramatsu, K., Ordoñez, C., Patrizi, F., Planells, M., Peitzman, A.B., Pekolj, J., Perdigao, F., Pereira, B.M., Pessaux, P., Pisano, M., Puyana, J.C., Rizoli, S., Portigliotti, L., Romito, R., Sakakushev, B., Sanei, B., Scatton, O., Serradilla-Martin, M., Schneck, A.S., Sissoko, M.L., Sobhani, I., Broek, R.P. Ten, Testini, M., Valinas, R., Veloudis, G., Vitali, G.C., Weber, D., Zorcolo, L., Giuliante, F., Gavriilidis, P., Fuks, D., and Sommacale, D.
Abstract: Contains fulltext : 238974.pdf (Publisher’s version ) (Open Access), Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
Published: 2021

20. Theoretical modelling of fibrinogen supplementation with therapeutic plasma, cryoprecipitate, or fibrinogen concentrate

Author: Collins, P. W., Solomon, C., Sutor, K., Crispin, D., Hochleitner, G., Rizoli, S., Schöchl, H., Schreiber, M., and Ranucci, M.
Published: 2014
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21. 42 Improving perioperative management of anemia and use of red blood cell transfusions for gastrointestinal surgery — results of a practice survey of general surgeons.

Author: Hallet, J., Yohanathan, L., Wallace, D., Callum, J., Lin, Y., McCluskey, S., Rizoli, S., McLeod, R., and Coburn, N.
Published: 2014

22. The open abdomen in trauma and non-trauma patients: WSES guidelines

Author: Coccolini, F, Roberts, D, Ansaloni, L, Ivatury, R, Gamberini, E, Kluger, Y, Moore, E, Coimbra, R, Kirkpatrick, A, Pereira, B, Montori, G, Ceresoli, M, Abu-Zidan, F, Sartelli, M, Velmahos, G, Fraga, G, Leppaniemi, A, Tolonen, M, Galante, J, Razek, T, Maier, R, Bala, M, Sakakushev, B, Khokha, V, Malbrain, M, Agnoletti, V, Peitzman, A, Demetrashvili, Z, Sugrue, M, Di Saverio, S, Martzi, I, Soreide, K, Biffl, W, Ferrada, P, Parry, N, Montravers, P, Melotti, R, Salvetti, F, Valetti, T, Scalea, T, Chiara, O, Cimbanassi, S, Kashuk, J, Larrea, M, Hernandez, J, Lin, H, Chirica, M, Arvieux, C, Bing, C, Horer, T, De Simone, B, Masiakos, P, Reva, V, Deangelis, N, Kike, K, Balogh, Z, Fugazzola, P, Tomasoni, M, Latifi, R, Naidoo, N, Weber, D, Handolin, L, Inaba, K, Hecker, A, Kuo-Ching, Y, Ordonez, C, Rizoli, S, Gomes, C, De Moya, M, Wani, I, Mefire, A, Boffard, K, Napolitano, L, Catena, F, Coccolini F., Roberts D., Ansaloni L., Ivatury R., Gamberini E., Kluger Y., Moore E. E., Coimbra R., Kirkpatrick A. W., Pereira B. M., Montori G., Ceresoli M., Abu-Zidan F. M., Sartelli M., Velmahos G., Fraga G. P., Leppaniemi A., Tolonen M., Galante J., Razek T., Maier R., Bala M., Sakakushev B., Khokha V., Malbrain M., Agnoletti V., Peitzman A., Demetrashvili Z., Sugrue M., Di Saverio S., Martzi I., Soreide K., Biffl W., Ferrada P., Parry N., Montravers P., Melotti R. M., Salvetti F., Valetti T. M., Scalea T., Chiara O., Cimbanassi S., Kashuk J. L., Larrea M., Hernandez J. A. M., Lin H. -F., Chirica M., Arvieux C., Bing C., Horer T., De Simone B., Masiakos P., Reva V., DeAngelis N., Kike K., Balogh Z. J., Fugazzola P., Tomasoni M., Latifi R., Naidoo N., Weber D., Handolin L., Inaba K., Hecker A., Kuo-Ching Y., Ordonez C. A., Rizoli S., Gomes C. A., De Moya M., Wani I., Mefire A. C., Boffard K., Napolitano L., Catena F., Coccolini, F, Roberts, D, Ansaloni, L, Ivatury, R, Gamberini, E, Kluger, Y, Moore, E, Coimbra, R, Kirkpatrick, A, Pereira, B, Montori, G, Ceresoli, M, Abu-Zidan, F, Sartelli, M, Velmahos, G, Fraga, G, Leppaniemi, A, Tolonen, M, Galante, J, Razek, T, Maier, R, Bala, M, Sakakushev, B, Khokha, V, Malbrain, M, Agnoletti, V, Peitzman, A, Demetrashvili, Z, Sugrue, M, Di Saverio, S, Martzi, I, Soreide, K, Biffl, W, Ferrada, P, Parry, N, Montravers, P, Melotti, R, Salvetti, F, Valetti, T, Scalea, T, Chiara, O, Cimbanassi, S, Kashuk, J, Larrea, M, Hernandez, J, Lin, H, Chirica, M, Arvieux, C, Bing, C, Horer, T, De Simone, B, Masiakos, P, Reva, V, Deangelis, N, Kike, K, Balogh, Z, Fugazzola, P, Tomasoni, M, Latifi, R, Naidoo, N, Weber, D, Handolin, L, Inaba, K, Hecker, A, Kuo-Ching, Y, Ordonez, C, Rizoli, S, Gomes, C, De Moya, M, Wani, I, Mefire, A, Boffard, K, Napolitano, L, Catena, F, Coccolini F., Roberts D., Ansaloni L., Ivatury R., Gamberini E., Kluger Y., Moore E. E., Coimbra R., Kirkpatrick A. W., Pereira B. M., Montori G., Ceresoli M., Abu-Zidan F. M., Sartelli M., Velmahos G., Fraga G. P., Leppaniemi A., Tolonen M., Galante J., Razek T., Maier R., Bala M., Sakakushev B., Khokha V., Malbrain M., Agnoletti V., Peitzman A., Demetrashvili Z., Sugrue M., Di Saverio S., Martzi I., Soreide K., Biffl W., Ferrada P., Parry N., Montravers P., Melotti R. M., Salvetti F., Valetti T. M., Scalea T., Chiara O., Cimbanassi S., Kashuk J. L., Larrea M., Hernandez J. A. M., Lin H. -F., Chirica M., Arvieux C., Bing C., Horer T., De Simone B., Masiakos P., Reva V., DeAngelis N., Kike K., Balogh Z. J., Fugazzola P., Tomasoni M., Latifi R., Naidoo N., Weber D., Handolin L., Inaba K., Hecker A., Kuo-Ching Y., Ordonez C. A., Rizoli S., Gomes C. A., De Moya M., Wani I., Mefire A. C., Boffard K., Napolitano L., and Catena F.
Abstract: Damage control resuscitation may lead to postoperative intra-abdominal hypertension or abdominal compartment syndrome. These conditions may result in a vicious, self-perpetuating cycle leading to severe physiologic derangements and multiorgan failure unless interrupted by abdominal (surgical or other) decompression. Further, in some clinical situations, the abdomen cannot be closed due to the visceral edema, the inability to control the compelling source of infection or the necessity to re-explore (as a "planned second-look" laparotomy) or complete previously initiated damage control procedures or in cases of abdominal wall disruption. The open abdomen in trauma and non-trauma patients has been proposed to be effective in preventing or treating deranged physiology in patients with severe injuries or critical illness when no other perceived options exist. Its use, however, remains controversial as it is resource consuming and represents a non-anatomic situation with the potential for severe adverse effects. Its use, therefore, should only be considered in patients who would most benefit from it. Abdominal fascia-to-fascia closure should be done as soon as the patient can physiologically tolerate it. All precautions to minimize complications should be implemented.
Published: 2018

23. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines

Author: Saverio, S. Di, Podda, M., Simone, B. De, Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., Angelis, N. De', Weber, D.G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E.E., Kelly, M., Soreide, K., Kashuk, J., Broek, R.P. ten, Gomes, C.A., Sugrue, M., Davies, R.J., Damaskos, D., Leppäniemi, A., Kirkpatrick, A., Peitzman, A.B., Fraga, G.P., Maier, R.V., Coimbra, R., Chiarugi, M., Sganga, G., Pisanu, A., Angelis, G.L. De', Tan, E.C.T.H., Goor, H. van, Pata, F., Carlo, I. Di, Chiara, O., Litvin, A., Campanile, F.C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z.J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L., Catena, F., Saverio, S. Di, Podda, M., Simone, B. De, Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., Angelis, N. De', Weber, D.G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E.E., Kelly, M., Soreide, K., Kashuk, J., Broek, R.P. ten, Gomes, C.A., Sugrue, M., Davies, R.J., Damaskos, D., Leppäniemi, A., Kirkpatrick, A., Peitzman, A.B., Fraga, G.P., Maier, R.V., Coimbra, R., Chiarugi, M., Sganga, G., Pisanu, A., Angelis, G.L. De', Tan, E.C.T.H., Goor, H. van, Pata, F., Carlo, I. Di, Chiara, O., Litvin, A., Campanile, F.C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z.J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L., and Catena, F.
Abstract: Contains fulltext : 225845.pdf (publisher's version ) (Open Access), BACKGROUND AND AIMS: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. METHODS: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. CONCLUSIONS: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital
Published: 2020

24. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines

Author: Di Saverio, S., Podda, M., De Simone, B., Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., De' Angelis, N., Weber, D. G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E. E., Kelly, M., Soreide, K., Kashuk, J., Ten Broek, R., Gomes, C. A., Sugrue, M., Davies, R. J., Damaskos, D., Leppaniemi, A., Kirkpatrick, A., Peitzman, A. B., Fraga, G. P., Maier, R. V., Coimbra, R., Chiarugi, M., Sganga, Gabriele, Pisanu, A., De' Angelis, G. L., Tan, E., Van Goor, H., Pata, F., Di Carlo, I., Chiara, O., Litvin, A., Campanile, F. C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z. J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L., Catena, F., Sganga G. (ORCID:0000-0001-5079-0395), Di Saverio, S., Podda, M., De Simone, B., Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., De' Angelis, N., Weber, D. G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E. E., Kelly, M., Soreide, K., Kashuk, J., Ten Broek, R., Gomes, C. A., Sugrue, M., Davies, R. J., Damaskos, D., Leppaniemi, A., Kirkpatrick, A., Peitzman, A. B., Fraga, G. P., Maier, R. V., Coimbra, R., Chiarugi, M., Sganga, Gabriele, Pisanu, A., De' Angelis, G. L., Tan, E., Van Goor, H., Pata, F., Di Carlo, I., Chiara, O., Litvin, A., Campanile, F. C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z. J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L., Catena, F., and Sganga G. (ORCID:0000-0001-5079-0395)
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: Use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospi
Published: 2020

25. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

Author: Sartelli, M., Kluger, Y., Ansaloni, L., Carlet, J., Brink, A., Hardcastle, T. C., Khanna, A., Chicom-Mefire, A., Rodríguez-Baño, J., Nathwani, D., Mendelson, M., Watkins, R. R., Pulcini, C., Beović, B., May, A. K., Itani, K. M. F., Mazuski, J. E., Fry, D. E., Coccolini, F., Rasxa, K., Montravers, P., Eckmann, C., Abbo, L. M., Abubakar, S., Abu-Zidan, F. M., Adesunkanmi, A. K., Al-Hasan, M. N., Althani, A. A., Ticas, J. E. A., Ansari, S., Ansumana, R., Da Silva, A. R. A. , Augustin, G. , Bala, M. , Balogh, Z. J. , Baraket, O. , Bassetti, M. , Bellanova, G. , Beltran, M. A. , Ben-Ishay, O. , Boermeester, M. A. , Brecher, S. M. , Bueno, J. , Cainzos, M. A. , Cairns, K. , Camacho-Ortiz, A. , Ceresoli, M. , Chandy, S. J. , Cherry-Bukowiec, J. R. , Cirocchi, R. , Colak, E. , Corcione, A. , Cornely, O. A. , Cortese, F. , Cui, Y. , Curcio, D. , Damaskos, D. , Dasx, K. , Delibegovic, S. , Demetrashvili, Z. be, De Simone, B. bf, De Souza, H. P. bg, De Waele, J. bh, Dhingra, S. bi, Diaz, J. J. bj, Di Carlo, I. bk, Di Marzo, F. bl, DI TOMASO, SAVERIO, S. , Dogjani, A. , Dorj, G. , Dortet, L. , Duane, T. M. , Dupont, H. , Egiev, V. N. , Eid, H. O. , Elmangory, El-Sayed Marei, H. , Enani, M. A. , Escandón-Vargas, K. , Faro, M. P. , J.r., Ferrada, P., Foghetti, D., Foianini, E., Fraga, G. P., Frattima, S., Gandhi, C., Gattuso, G., Giamarellou, E., Ghnnam, W., Gkiokas, G., Girardis, M., Goff, D. A., Gomes, C. A., Gomi, H., Gronerth, R. I. G., Guirao, X., Guzman-Blanco, M., Haque, M., Hecker, A., Hell, M., Herzog, T., Hicks, L., Kafka-Ritsch, R., Kao, L. S., Kanj, S. S., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kashuk, J., Kenig, J., Khamis, F., Khokha, V., Kiguba, R., Kirkpatrick, A. W., Kørner, H., Koike, K., Kok, K. Y. Y., Kon, K., Kong, V., Inaba, K., Ioannidis, O., Isik, A., Iskandar, K., Labbate, M., Labricciosa, F. M., Lagrou, K., Lagunes, L., Latifi, R., Lasithiotakis, K., Laxminarayan, R., Lee, J. G., Leone, M., Leppäniemi, A., Li, Y., Liang, S. Y., Liau, K. -.H., Litvin, A., Loho, T., Lowman, W., Machain, G. Mf, Maier, R. V., Manzano-Nunez, R., Marinis, A., Marmorale, C., Martin-Loeches, I., Marwah, S., Maseda, E., McFarlane, M., BEZERRA DE MELO PEREIRA NUNES, CINTIA, R. , Melotti, R. , Memish, Z. , Mertz, D. , Mesina, C. , Menichetti, F. , Mishra, S. K. , Montori, G. , Moore, E. E. , Moore, F. A. , Naidoo, NAPOLITANO, NELLO, L. , Negoi, I. , Nicolau, D. P. , Nikolopoulos, I. , Nord, C. E. , Ofori-Asenso, R. , Olaoye, I. , Omari, A. H. , Ordoñez, C. A. , Ouadii, M. , Ouedraogo, A. , Pagani, L. , Paiva, J. A. , Parreira, J. G. , Pata, F. fm, Pereira, J., Pereira, N. R., Petrosillo, N., Picetti, E., Pintar, T., Ponce-De-Leon, A., Popovski, Z., Poulakou, G., Preller, J., Guerrero, A. P., Pupelis, G., Quiodettis, M., Rawson, T. M., Reichert, M., Reinhart, K., Rems, M., Rello, J., Rizoli, S., ROBERTS, HENRI JOHAN EDUARD, Rubio-Perez, I., Ruppé, E., Sakakushev, B., Sall, I., Kafil, H. S. j, Sanders, J., Sato, N., Sawyer, R. G., T. , Scibé, R. , Scudeller, L. , Lohse, H. S. , Sganga, G. , Shafiq, N. , Shah, J. N. , Spigaglia, P. , Suroowan, S. , Tsioutis, C. , Sifri, C. D. , Siribumrungwong, B. , Sugrue, M. , Talving, P. , Tan, B. K. , Tarasconi, A. , Tascini, C. , Tilsed, J. , Timsit, J. -.F. , Tumbarello, M. , Trung, N. T. , Ulrych, J. , Uranues, S. , Velmahos, G. , Vereczkei, A. G. , Viale, P. , Estape, J. V. , Viscoli, C. , Wagenlehner, F. , Wright, B. J. , Xiao, Y. , Yuan, K. -.C. , Zachariah, S. K. , Zahar, J. R. , Mergulhão, P. , Catena, Réanimation Médico-Chirurgicale, Groupe Hospitalier Paris Saint-Joseph, University Hospital Virgen Macarena, Internal Medicine Department, Universidad de Sevilla, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U912 INSERM - Aix Marseille Univ - IRD), Institut de Recherche pour le Développement (IRD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Service d'anesthésie - réanimation chirurgicale, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Klinik I für Innere Medizin und Zentrum für Klinische Studien (ZKS) 01KN0706, Universitätsklinikum Köln (Uniklinik Köln), AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), CHU Amiens-Picardie, Paracelsus Medizinische Privatuniversität = Paracelsus Medical University (PMU), Université Catholique de Louvain = Catholic University of Louvain (UCL), Center for Disease Dynamics, Economics & Policy (CDDEP), Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Hartford Hospital, Department of Laboratory Medicine, Karolinska Institutet [Stockholm], Pathogénèse et contrôle des infections chroniques (PCCI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre Hospitalier Universitaire de Montpellier (CHU Montpellier ), Instituto Nacional de Matemática Pura e Aplicada (IMPA), Instituto Nacional de matematica pura e aplicada, 4th Department of Internal Medicine, ATTIKON University General Hospital, Department of Anesthesiology and Intensive Care, Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany], Critical Care Department, Joan XXIII University Hospital, Departmet of Infectious, Parasitic and Immune-Mediated Disease, Istituto Superiore di Sanita [Rome], Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Department of Internal Medicine, Geriatrics and Nephrologic Diseases, Section of Infectious Diseases, S.Orsola-Malpighi Hospital, Alma Mater Studiorum University of Bologna (UNIBO), Infectious Diseases, University of Genoa (UNIGE), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Groupe Hospitalier Paris Saint-Joseph (hpsj), Universidad de Sevilla / University of Sevilla, Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Nice Sophia Antipolis (1965 - 2019) (UNS), Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Istituto Superiore di Sanità (ISS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Università degli studi di Genova = University of Genoa (UniGe), Sartelli, Massimo, Kluger, Yoram, Ansaloni, Luca, Carlet, Jean, Dorj, Gereltuya, Catena, Fausto, [Sartelli, Massimo] Macerata Hosp, Dept Surg, Macerata, Italy, [Scibe, Rodolfo] Macerata Hosp, Dept Surg, Macerata, Italy, [Kluger, Yoram] Rambam Hlth Care Campus, Dept Gen Surg, Div Surg, Haifa, Israel, [Ben-Ishay, Ofir] Rambam Hlth Care Campus, Dept Gen Surg, Div Surg, Haifa, Israel, [Ansaloni, Luca] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Coccolini, Federico] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Ceresoli, Marco] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Montori, Giulia] Papa Giovanni XXIII Hosp, Gen Surg Dept, Bergamo, Italy, [Carlet, Jean] World Alliance Antibiot Resistance, Paris, France, [Brink, Adrian] Milpark Hosp, Ampath Natl Lab Serv, Dept Clin Microbiol, Johannesburg, South Africa, [Brink, Adrian] Univ Cape Town, Dept Med, Div Infect Dis & HIV Med, Cape Town, South Africa, [Hardcastle, Timothy C.] Inkosi Albert Luthuli Cent Hosp, Trauma Serv, Durban, South Africa, [Hardcastle, Timothy C.] Nelson R Mandela Sch Clin Med, Dept Surg, Durban, South Africa, [Khanna, Ashish] Ctr Crit Care, Anaesthesiol Inst, Cleveland, OH USA, [Khanna, Ashish] Cleveland Clin, Dept Outcomes Res, Cleveland, OH 44106 USA, [Chicom-Mefire, Alain] Univ Buea, Dept Surg & Obstet Gynaecol, Buea, Cameroon, [Foianini, Esteban] Univ Buea, Dept Surg & Obstet Gynaecol, Buea, Cameroon, [Rodriguez-Bano, Jesus] Hosp Univ Virgen Macarena & Virge del Rocio IbiS, Unidad Clin Interctr Enfermedades Infecciosas Mic, Seville, Spain, [Rodriguez-Bano, Jesus] Univ Seville, Dept Med, Seville, Spain, [Nathwani, Dilip] Ninewells Hosp & Med Sch, Dundee, Scotland, [Mendelson, Marc] Univ Cape Town, Groote Schuur Hosp, Dept Med, Div Infect Dis & HIV Med, Cape Town, South Africa, [Watkins, Richard R.] Cleveland Clin Akron Gen, Div Infect Dis, Akron, OH USA, [Watkins, Richard R.] Northeast Ohio Med Univ, Rootstown, OH USA, [Pulcini, Celine] Lorraine Univ, EA APEMAC 4360, Nancy, France, [Pulcini, Celine] Nancy Univ Hosp, Infect Dis Dept, Nancy, France, [Beovic, Bojana] Univ Med Ctr Ljubljana, Ljubljana, Slovenia, [Beovic, Bojana] Univ Ljubljana, Fac Med, Ljubljana, Slovenia, [May, Addison K.] Vanderbilt Univ, Med Ctr, Div Trauma & Surg Crit Care, Nashville, TN USA, [Itani, Kamal M. F.] Boston Univ, Dept Surg, VA Boston Hlth Care Syst, Boston, MA 02215 USA, [Itani, Kamal M. F.] Harvard Med Sch, Boston, MA USA, [Mazuski, John E.] Washington Univ, Sch Med, Dept Surg, St Louis, MO 63110 USA, [Fry, Donald E.] Northwestern Univ, Feinberg Sch Med, Dept Surg, Chicago, IL 60611 USA, [Fry, Donald E.] Univ New Mexico, Sch Med, Albuquerque, NM 87131 USA, [Rasa, Kemal] Anadolu Med Ctr, Dept Surg, Kocaali, Turkey, [Montravers, Philippe] Bichat Claude Bernard Univ Hosp, Paris Diderot Sorbonne Cite Univ, Anesthesiol & Crit Care Med, HUPNSV, Paris, France, [Eckmann, Christian] Hannover Med Sch, Acad Hosp, Dept Gen Visceral & Thorac Surg, Peine, Germany, [Abbo, Lilian M.] Univ Miami, Miller Sch Med, Jackson Hlth Syst, Div Infect Dis, Miami, FL 33136 USA, [Abbo, Lilian M.] Bayero Univ, Dept Nursing Sci, Kano, Nigeria, [Abubakar, Salisu] UAE Univ, Coll Med & Hlth Sci, Dept Surg, Al Ain, U Arab Emirates, [Abu-Zidan, Fikri M.] Obafemi Awolowo Univ, Coll Hlth Sci, Dept Surg, Ife, Nigeria, [Al-Hasan, Majdi N.] Univ South Carolina, Sch Med, Dept Med, Div Infect Dis, Columbia, SC USA, [Althani, Asma A.] Qatar Univ, Biomed Res Ctr, Doha, Qatar, [Marei, Hany El-Sayed] Qatar Univ, Biomed Res Ctr, Doha, Qatar, [Ticas, Jorge Eduardo Alvarenga] Hosp Nacl Ros, Emergency Unit, San Salvador, El Salvador, [Ansari, Shamshul] Oita Univ, Dept Environm & Prevent Med, Fac Med, Oita, Japan, [Ansari, Shamshul] Chitwan Med Coll, Dept Microbiol, Bharatpur, Nepal, [Ansumana, Rashid] Univ Liverpool, Liverpool Sch Trop Med, Ctr Neglected Trop Dis, Bo, Sierra Leone, [Ansumana, Rashid] Njala Univ, Mercy Hosp, Res Lab, Bo, Sierra Leone, [Araujo da Silva, Andre Ricardo] Prontobaby Hosp Crianca, Infect Control Comm, Rio De Janeiro, Brazil, [Augustin, Goran] Univ Hosp Ctr, Dept Surg, Zagreb, Croatia, [Bala, Miklosh] Hadassah Hebrew Univ Med Ctr, Trauma & Acute Care Surg Unit, Jerusalem, Israel, [Balogh, Zsolt J.] John Hunter Hosp, Dept Traumatol, Newcastle, NSW, Australia, [Balogh, Zsolt J.] Univ Newcastle, Newcastle, NSW, Australia, [Baraket, Oussema] Bizerte Hosp, Dept Surg, Bizerte, Tunisia, [Bassett, Matteo] Santa Maria Misericordia Univ Hosp, Infect Dis Div, Udine, Italy, [Bellanova, Giovanni] SS Annunziata Hosp, Dept Surg, Taranto, Italy, [Beltran, Marcelo A.] Hosp San Juan Dios, Dept Gen Surg, La Serena, Chile, [Biffl, Walter L.] Queens Med Ctr, Acute Care Surg, Honolulu, HI USA, [Boermeester, Marja A.] Acad Med Ctr, Dept Surg, Amsterdam, Netherlands, [Brecher, Stephen M.] Boston Univ, Sch Med, VA Boston HealthCare Syst, Dept Pathol & Lab Med, Boston, MA 02118 USA, [Brecher, Stephen M.] Boston Univ, Sch Med, Dept Pathol & Lab Med, Boston, MA 02118 USA, [Bueno, Juan] Fdn Ctr Invest Bioprospecc & Biotecnol Biodivers, Barranquilla, Colombia, [Cainzos, Miguel A.] Hosp Clin Univ, Dept Surg, Santiago De Compostela, Spain, [Cairns, Kelly] Alfred Hlth, Pharm Dept, Melbourne, Vic, Australia, [Camacho-Ortiz, Adrian] Hosp Univ Dr Jose Eleuterio Gonzalez, Hosp Epidemiol & Infect Dis, Monterrey, Mexico, [Chandy, Sujith J.] Christian Med Coll & Hosp, Dept Pharmacol & Clin Pharmacol, Vellore, Tamil Nadu, India, [Cherry-Bukowiec, Jill R.] Univ Michigan, Dept Surg, Div Acute Care Surg, Ann Arbor, MI 48109 USA, [Cirocchi, Roberto] Univ Perugia, Dept Gen & Oncol Surg, Terni, Italy, [Colak, Elif] Hlth Sci Univ, Samsun Training & Res Hosp, Dept Gen Surg, Samsun, Turkey, [Corcione, Antonio] AORN Colli Vincenzo Monaldi Hosp, Anesthesia & Intens Care Unit, Naples, Italy, [Cornely, Oliver A.] Univ Cologne, German Ctr Infect Res DZIF, Dept Internal Med 1, Cologne Excellence Cluster Cellular Stress Respon, Cologne, Germany, [Cortese, Francesco] San Filippo Neris Hosp, Emergency Surg Unit, Rome, Italy, [Cui, Yunfeng] Tianjin Med Univ, Tianjin Nankai Hosp, Dept Surg, Nankai Clin Sch Med, Tianjin, Peoples R China, [Curcio, Daniel] Buenos Aires Univ, Infectol Inst SRL, Buenos Aires, DF, Argentina, [Damaskos, Dimitris] Royal Infirm Edinburgh NHS Trust, Dept Surg, Edinburgh, Midlothian, Scotland, [Das, Koray] Ankara Numune Training & Res Hosp, Dept Surg, Adana, Turkey, [Delibegovic, Samir] Univ Clin Ctr Tuzla, Dept Surg, Tuzla, Bosnia & Herceg, [Deme-Trashvili, Zaza] Kipshidze Cent Univ Hosp, Dept Gen Surg, Tbilisi, Georgia, [De Simone, Belinda] Cannes Hosp, Dept Digest Surg, Cannes, France, [de Souza, Hamilton Petry] Pontificia Univ Catolica Rio Grande do Sul PUCRS, Sch Med, Dept Surg, Porto Alegre, RS, Brazil, [De Waele, Jan] Ghent Univ Hosp, Dept Crit Care Med, Ghent, Belgium, [Dhingra, Sameer] Univ West Indies, Eric Williams Med Sci Complex, Sch Pharm, Fac Med Sci, Uriah Butler Highway, Champ Fleurs, Trinidad Tobago, [Diaz, Jose J.] Univ Maryland, R Adams Cowley Shock Trauma Ctr, Div Acute Care Surg, Program Trauma, Baltimore, MD 21201 USA, [Di Carlo, Isidoro] Univ Catania, Cannizzaro Hosp, Dept Surg Sci, Catania, Italy, [Di Marzo, Francesco] Versilia Hosp, Gen Surg, Usl Nordovest, Tuscany, Italy, [Di Saverio, Salomone] Maggiore Hosp, Dept Surg, Bologna, Italy, [Dogjani, Agron] Univ Hosp Trauma, Dept Surg, Tirana, Albania, [Dorj, Gereltuya] Mongolian Natl Univ Med Sci, Sch Pharm, Ulaanbaatar, Mongolia, [Dortet, Laurent] Paris Sud Univ, Bicetre Hosp, Dept Microbiol, La Kremlin Bicetre, France, [Duane, Therese M.] John Peter Smith Hlth Network, Dept Surg, Ft Worth, TX USA, [Dupont, Herve] Univ Picardie Jules Verne, CHU Amiens Picardie, Dept Anesthesie Reanimat, Amiens, France, [Dupont, Herve] Univ Picardie Jules Verne, INSERM, U1088, Amiens, France, [Egiev, Valery N.] Pirogov Russian Natl Res Med Univ, Dept Surg, Moscow, Russia, [Eid, Hani O.] Al Ain Hosp, Mediclin Middle East, Dept Emergency Med, Al Ain, U Arab Emirates, [Elmangory, Mutasim] Fed Minist Hlth, Sudan Natl Publ Hlth Lab, Khartoum, Sudan, [Enani, Mushira Abdulaziz] King Fahad Med City, Div Infect Dis, Dept Med, Riyadh, Saudi Arabia, [Escandon-Vargas, Kevin] Univ Valle, Escuela Med, Fac Salud, Cali, Colombia, [Faro Junior, Mario P.] ABC Med Sch, Dept Gen Surg Trauma, Santo Andre, SP, Brazil, [Faro Junior, Mario P.] ABC Med Sch, Emergency Surg Div, Santo Andre, SP, Brazil, [Ferrada, Paula] Virginia Commonwealth Univ, Dept Surg, Richmond, VA USA, [Foghetti, Domitilla] Pesaro Hosp, Dept Surg, Pesaro, Italy, Clin Foianini, Dept Surg, Santa Cruz, Bolivia, [Fraga, Gustavo P.] Univ Campinas Unicamp, Sch Med Sci, Dept Surg, Div Trauma Surg, Campinas, SP, Brazil, [Frattima, Sabrina] Ist Clin San Rocco Franciacorta, Brescia, Italy, [Gandhi, Chinmay] Bharati Vidyapeeth Deemed Univ Med Coll & Hosp, Dept Surg, Sangli, Maharashtra, India, [Gattuso, Gianni] C Poma Hosp, Infect Dis Dept, Mantua, Italy, [Giamarellou, Eleni] Hygeia Gen Hosp, Dept Internal Med 6, Athens, Greece, [Ghnnam, Wagih] Mansoura Univ, Mansoura Fac Med, Dept Gen Surg, Mansoura, Egypt, [Gkiokas, George] Natl & Kapodistrian Univ Athens, Aretaieion Univ Hosp, Dept Surg 2, Athens, Greece, [Girardis, Massimo] Modena Univ Hosp, Intens Care Unit, Modena, Italy, [Goff, Debbie A.] Ohio State Univ, Wexner Med Ctr, Columbus, OH 43210 USA, [Gomes, Carlos Augusto] Hosp Univ Terezinha Jesus, Dept Surg, Fac Ciencias Med & Saude Juiz de Fora, Juiz De Fora, Brazil, [Gomi, Harumi] Univ Tsukuba, Mito Kyodo Gen Hosp, Ctr Global Hlth, Mito, Ibaraki, Japan, [Guerra Gronerth, Rosio Isabel] Peruvian Navy Med Ctr, Lima, Peru, [Guirao, Xavier] Parc Tauli Univ Hosp, Dept Gen Surg, Unit Endocrine Head & Neck Surg, Sabadell, Spain, [Guirao, Xavier] Parc Tauli Univ Hosp, Dept Gen Surg, Unit Surg Infect Support, Sabadell, Spain, [Guzman-Blanco, Manuel] Hosp Privado Ctr Med Caracas, Caracas, Venezuela, [Guzman-Blanco, Manuel] Hosp Vargas Caracas, Caracas, Venezuela, [Haque, Mainul] Univ Pertahanan Nasional Malaysia, Natl Def Univ Malaysia, Unit Pharmacol, Fac Med & Def Hlth, Kuala Lumpur, Malaysia, [Reichert, Martin] Univ Pertahanan Nasional Malaysia, Natl Def Univ Malaysia, Unit Pharmacol, Fac Med & Def Hlth, Kuala Lumpur, Malaysia, [Hecker, Andreas] Univ Hosp Giessen, Dept Gen & Thorac Surg, Giessen, Germany, [Hell, Markus] Paracelsus Med Univ, Acad Teaching Lab, Clin Microbiol & Infect Control, MEDILAB Dr Mustafa Dr Richter OG, Salzburg, Austria, [Herzog, Torsten] Ruhr Univ Bochum, St Josef Hosp, Dept Surg, Bochum, Germany, [Hicks, Lauri] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA, [Kafka-Ritsch, Reinhold] Innsbruck Med Univ, Dept Visceral Transplant & Thorac Surg, Innsbruck, Austria, [Kao, Lillian S.] Univ Texas Hlth Sci Ctr Houston, Dept Surg, Houston, TX 77030 USA, [Kanj, Souha S.] Amer Univ Beirut, Dept Internal Med, Div Infect Dis, Beirut, Lebanon, [Kaplan, Lewis J.] Univ Penn, Perelman Sch Med, Philadelphia VA Med Ctr, Dept Surg, Philadelphia, PA 19104 USA, [Kapoor, Garima] Gandhi Med Coll, Dept Microbiol, Bhopal, India, [Karamarkovic, Aleksandar] Univ Belgrade, Clin Emergency Surg, Med Fac, Belgrade, Serbia, [Kashuk, Jeffry] Tel Aviv Univ, Dept Surg, Assia Med Grp, Sackler Sch Med, Tel Aviv, Israel, [Kenig, Jakub] Jagiellonian Univ, Med Coll, Dept Gen Surg 3, Krakow, Poland, [Khamis, Faryal] Royal Hosp, Dept Internal Med, Muscat, Oman, [Khokha, Vladimir] City Hosp, Dept Emergency Surg, Mozyr, BELARUS, [Kiguba, Ronald] Makerere Univ, Dept Pharmacol & Therapeut, Coll Hlth Sci, Kampala, Uganda, [Kirkpatrick, Andrew W.] Foothills Med Ctr, Gen Acute Care Abdominal Wall Reconstruct & Traum, Calgary, AB, Canada, [Korner, Hartwig] Stavanger Univ Hosp, Dept Gastrointestinal Surg, Stavanger, Norway, [Koike, Kaoru] Kyoto Univ, Grad Sch Med, Dept Primary Care & Emergency Med, Kyoto, Japan, [Kok, Kenneth Y. Y.] Brunei Canc Ctr, Dept Surg, Jerudong Pk, Jerudong, Brunei, [Kon, Kateryna] Kharkiv Natl Med Univ, Dept Microbiol Virol & Immunol, Kharkov, Ukraine, [Kong, Victor] Edendale Hosp, Dept Surg, Pietermaritzburg, South Africa, [Inaba, Kenji] Univ Southern Calif, Los Angeles Cty & Univ So Cali fornia Med Ctr, Div Acute Care Surg & Surg Crit Care, Dept Surg, Los Angeles, CA USA, [Ioannidis, Orestis] Aristotle Univ Thessaloniki, Gen Hosp G Papanikolaou, Surg Dept 4, Med Sch, Thessaloniki, Greece, [Isik, Arda] Erzincan Univ, Dept Gen Surg, Fac Med, Erzincan, Turkey, [Iskandar, Katia] Lebanese Int Univ, Dept Pharm, Beirut, Lebanon, [Labbate, Maurizio] Univ Technol Sydney, Sch Life Sci, Sydney, NSW, Australia, [Labbate, Maurizio] Univ Technol Sydney, Inst I3, Sydney, NSW, Australia, [Labricciosa, Francesco M.] UNIVPM, Dept Biomed Sci & Publ Hlth, Unit Hyg Prevent Med & Publ Hlth, Ancona, Italy, [Lagrou, Katrien] Univ Hosp Leuven, Clin Dept Lab Med, Leuven, Belgium, [Lagrou, Katrien] Katholieke Univ Leuven, Dept Microbiol & Immunol, Leuven, Belgium, [Lagunes, Leonel] Hosp Cent Dr Ignacio Morones Prieto, San Luis Potosi, Mexico, [Latifi, Rifat] Univ Arizona, Dept Surg, Div Trauma, Tucson, AZ USA, [Lasithiotakis, Kostas] York Teaching Hosp NHS Fdn Trust, Dept Surg, York, N Yorkshire, England, [Laxminarayan, Ramanan] Ctr Dis Dynam Econ & Policy, Washington, DC USA, [Lee, Jae Gil] Yonsei Univ, Coll Med, Dept Surg, Seoul, South Korea, [Leone, Marc] Aix Marseille Univ, Hop Nord, AP HM, Dept Anaesthesiol & Crit Care, Marseille, France, [Leppaniemi, Ari] Univ Hosp Meilahti, Abdominal Ctr, Helsinki, Finland, [Li, Yousheng] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 9, Dept Surg, Shanghai, Peoples R China, [Liang, Stephen Y.] Washington Univ, Sch Med, Div Infect Dis, Div Emergency Med, St Louis, MO USA, [Liau, Kui-Hin] Natl Univ Singapore, Mt Elizabeth Novena Hosp, Singapore & Yong Loo Lin Sch Med, Dept Surg,Liau KH Consulting, Singapore, Singapore, [Litvin, Andrey] Immanuel Kant Balt Fed Univ, Surg Disciplines, Reg Clin Hosp, Kaliningrad, Russia, [Loho, Tonny] Univ Indonesia, Cipto Mangunkusumo Gen Hosp, Dept Clin Pathol, Div Infect Dis,Fac Med, Jakarta, Indonesia, [Lowman, Warren] Univ Witwatersrand, Sch Pathol, Vermaak Partners Pathcare Pathologists, Clin Microbiol & Infect Dis,Fac Hlth Sci, Johannesburg, South Africa, [Lowman, Warren] Wits Donald Gordon Med Ctr, Johannesburg, South Africa, [Machain, Gustavo M.] Univ Nacl Asuncion, Dept Surg, Asuncion, Paraguay, [Segovia Lohse, Helmut] Univ Nacl Asuncion, Dept Surg, Asuncion, Paraguay, [Maier, Ronald V.] Univ Washington, Dept Surg, Seattle, WA 98195 USA, [Manzano-Nunez, Ramiro] Fdn Valle Lili, Clin Res Ctr, Cali, Colombia, [Marinis, Athanasios] Tzane Gen Hosp, Dept Surg 1, Piraeus, Greece, [Marmorale, Cristina] Univ Politecn Marche, Dept Surg, Ancona, Italy, [Martin-Loeches, Ignacio] St James Univ Hosp, Trin Ctr Hlth Sci, Dept Clin Med, Wellcome Trust HRB Clin Res,MICRO, Dublin, Ireland, [Marwah, Sanjay] Postgrad Inst Med Sci, Dept Surg, Rohtak, Haryana, India, [Maseda, Emilio] Hosp Univ La Paz Madrid, Serv Anestesia & Reanimac, Madrid, Spain, [McFarlane, Michael] Univ Hosp West Indies, Dept Surg Radiol, Kingston, Jamaica, [de Melo, Renato Bessa] Ctr Hosp Sao Joao, Gen Surg Dept, Porto, Portugal, [Melotti, Maria Rita] Alma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Anesthesiol & Intens Care, Bologna, Italy, [Memish, Ziad] Minist Hlth, Prince Mohamed Bin Abdulaziz Hosp, Dept Med, Infect Dis Div, Riyadh, Saudi Arabia, [Mertz, Dominik] McMaster Univ, Dept Med, Hamilton, ON, Canada, [Mertz, Dominik] McMaster Univ, Dept Clin Epidemiol & Biostat, Dept Pathol & Mol Med, Hamilton, ON, Canada, [Mesina, Cristian] Emergency Hosp Craiova, Surg Clin 2, Craiova, Romania, [Menichetti, Francesco] Univ Hosp Pisa, Infect Dis Unit, Pisa, Italy, [Mishra, Shyam Kumar] Tribhuvan Univ, Teaching Hosp, Inst Med, Dept Microbiol, Kathmandu, Nepal, [Moore, Ernest E.] Univ Colorado, Denver 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Hlth Protect Res Unit Healthcare Associated Infec, Hammersmith Campus, London, England, [Reinhart, Konrad] Jena Univ Hosp, Dept Anesthesiol & Intens Care Med, Jena, Thuringen, Germany, [Rems, Miran] Jesenice Gen Hosp, Dept Gen Surg, Jesenice, Slovenia, [Rello, Jordi] VHIR, Dept Clin Res & Innovat Pneumonia & Sepsis, Barcelona, Spain, [Rizoli, Sandro] Univ Toronto, St Michaels Hosp, Trauma & Acute Care Serv, Toronto, ON, Canada, [Roberts, Jason] Univ Queensland, Fac Med, Brisbane, Qld, Australia, [Rubio-Perez, Ines] La Paz Univ Hosp, Gen Surg Dept, Colorectal Surg Unit, Madrid, Spain, [Ruppc, Etienne] Bichat Claude Bernard Univ Hosp, Paris Diderot Sorbonne Univ, Serv Bacteriol, HUPNSV, Paris, France, [Sakakushev, Boris] Univ Hosp St George, Med Univ, Gen Surg Dept, Plovdiv, Bulgaria, [Sall, Ibrahima] Mil Teaching Hosp, Gen Surg Dept, Dakar, Senegal, [Kafil, Hossein Samadi] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran, [Sanders, James] JPS Hlth Network, Ft Worth, TX USA, [Sato, Norio] Ehime Univ, Grad Sch Med, Dept Aeromed Serv Emergency & Trauma Care, Matsuyama, Ehime, Japan, [Sawyer, Robert G.] Western Michigan Univ, Sch Med, Dept Surg, Kalamazoo, MI 49008 USA, [Scalea, Thomas] Univ Maryland, Sch Med, Dept Trauma Surg, Baltimore, MD 21201 USA, [Scudeller, Luigia] IRCCS Policlin San Matteo Fdn, Clin Epidemiol Unit, Pavia, Italy, [Sganga, Gabriele] Univ Cattolica Sacro Cuore, Policlin A Gemelli, Dept Surg, Rome, Italy, [Shafiq, Nusrat] Postgrad Inst Med Educ & Res, Dept Pharmacol, Chandigarh, India, [Shah, Jay N.] Patan Acad Hlth Sci, Dept Surg Patan Hosp, Kathmandu, Nepal, [Spigaglia, Patrizia] Ist Super Sanita, Dept Infect Dis, Rome, Italy, [Suroowan, Shanoo] Univ Mauritius, Dept Hlth Sci, Fac Sci, Reduit, Mauritius, [Tsioutis, Constantinos] European Univ Cyprus, Sch Med, Nicosia, Cyprus, [Sifri, Costi D.] Univ Virginia Hlth Syst, Off Hosp Epidemiol Infect Prevent & Control, Charlottesville, VA USA, [Siribumrungwong, Boonying] Thammasat Univ Hosp, Thammasat Univ, Dept Surg, Fac Med, Pathum Thani, Thailand, [Sugrue, Michael] Letterkenny Hosp, Gen Surg Dept, Letterkenny, Ireland, [Talving, Peep] North Estonia Med Ctr, Dept Surg, Tallinn, Estonia, [Tan, Boun Kim] Ctr Hosp St Joseph St Luc, Intens Care Unit, Lyon, France, [Tarasconi, Antonio] Parma Maggiore Hosp, Dept Emergency Surg, Parma, Italy, [Catena, Fausto] Parma Maggiore Hosp, Dept Emergency Surg, Parma, Italy, [Tascini, Carlo] Cotugno Hosp, Azienda Osped Colli, Div Infect Dis 1, Naples, Italy, [Tilsed, Jonathan] Hull & East Yorkshire Hosp NHS Trust, Surg Hlth Care Grp, Kingston Upon Hull, N Humberside, England, [Timsit, Jean-Francois] Hop Xavier Bichat, PHP Med & Infect Dis ICU, Paris, France, [Tumbarello, Mario] Catholic Univ, Inst Infect Dis, Rome, Italy, [Ngo Tat Trung] Tran Hung Dao Hosp, Dept Mol Biol, Hanoi, Vietnam, [Ulrych, Jan] Charles Univ Prague, Fac Med 1, Dept Surg 1, Prague, Czech Republic, [Ulrych, Jan] Gen Univ Hosp Prague, Prague, Czech Republic, [Uranues, Selman] Med Univ Graz, Dept Surg, Graz, Austria, [Velmahos, George] Massachusetts Gen Hosp, Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USA, [Vereczkei, Andras G.] Med Sch Univ Pecs, Dept Surg, Pecs, Hungary, [Viale, Pierluigi] Alma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy, [Vila Estape, Jordi] Univ Barcelona, ISGlobal Hosp Clin, Inst Salud Global, Barcelona, Spain, [Viscoli, Claudio] Univ Genoa DISSAL, Osped Policlin San Martino IRCCS Oncol, Infect Dis Unit, Genoa, Italy, [Wagenlehner, Florian] Univ Giessen, Dept Urol Pediat Urol & Androl, Med Fac Justus Liebig, Giessen, Germany, [Wright, Brian J.] SUNY Stony Brook, Sch Med, Dept Emergency Med & Neurosurg, Stony Brook, NY 11794 USA, [Xiao, Yonghong] Zhejiang Univ, Affilliated Hosp 1, State Key Lab Diag & Treatment Infect Dis, Hangzhou, Zhejiang, Peoples R China, [Yuan, Kuo-Ching] Chang Gung Mem Hosp, Trauma & Emergency Surg Dept, Taoyuan, Taiwan, [Zachariah, Sanoop K.] MOSC Med Coll Kolenchery, Dept Surg, Cochin, Kerala, India, [Zahar, Jean Ralph] Angers Univ, CHU Angers, Infect Control Unit, Angers, France, COMBE, Isabelle, Sartelli, M, Kluger, Y, Ansaloni, L, Carlet, J, Brink, A, Hardcastle, T, Khanna, A, Chicom-Mefire, A, Rodriguez-Bano, J, Nathwani, D, Mendelson, M, Watkins, R, Pulcini, C, Beovic, B, May, A, Itani, K, Mazuski, J, Fry, D, Coccolini, F, Rasxa, K, Montravers, P, Eckmann, C, Abbo, L, Abubakar, S, Abu-Zidan, F, Adesunkanmi, A, Al-Hasan, M, Althani, A, Ticas, J, Ansari, S, Ansumana, R, Da Silva, A, Augustin, G, Bala, M, Balogh, Z, Baraket, O, Bassetti, M, Bellanova, G, Beltran, M, Ben-Ishay, O, Biffl, W, Boermeester, M, Brecher, S, Bueno, J, Cainzos, M, Cairns, K, Camacho-Ortiz, A, Ceresoli, M, Chandy, S, Cherry-Bukowiec, J, Cirocchi, R, Colak, E, Corcione, A, Cornely, O, Cortese, F, Cui, Y, Curcio, D, Damaskos, D, Dasx, K, Delibegovic, S, Demetrashvili, Z, De Simone, B, De Souza, H, De Waele, J, Dhingra, S, Diaz, J, Di Carlo, I, Di Marzo, F, Di 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Subjects: 0301 basic medicine, antibiotic agent, antifungal agent antiinfective agent, Antifungal Agents, Drug Resistance, Declaration, Inappropriate Prescribing, 030230 surgery, Global Health, Antimicrobial Stewardship, Microbial, 0302 clinical medicine, Anti-Infective Agents, Health care, Global health, Antimicrobial stewardship, Antibiotic prophylaxis, Antibiotic stewardship, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Drug Resistance, Microbial, Public relations, Antimicrobial, Operative, Anti-Bacterial Agents, Antibiotic Prophylaxis, Humans, Surgical Procedures, Operative, Surgical Wound Infection, Surgery, Microbiology (medical), Infectious Diseases, 3. Good health, surgical infections, medicine.medical_specialty, 030106 microbiology, Guidelines, 03 medical and health sciences, Antibiotic resistance, medicine, Ventilator-associated pneumonia, Adults, Surgical Procedures, business.industry, Carbapenems, Therapy, business, hospitals, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: International audience; This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages.
Published: 2017

26. Cryoprecipitate transfusion: assessing appropriateness and dosing in trauma

Author: Nascimento, B., Rizoli, S., Rubenfeld, G., Fukushima, R., Ahmed, N., Nathens, A., Lin, Y., and Callum, J.
Published: 2011
Full Text: View/download PDF

27. Prevention and treatment of coagulopathy in patients receiving massive transfusions

Author: Levi, M., Fries, D., Gombotz, H., van der Linden, Ph., Nascimento, B., Callum, J. L., Bélisle, S., Rizoli, S., Hardy, J. -F., Johansson, P. I., Samama, C. M., Grottke, O., Rossaint, R., Henny, C. P., Goslings, J. C., Theusinger, O. M., Spahn, D. R., Ganter, M. T., Hess, J. R., Dutton, R. P., Scalea, T. M., Levy, J. H., Spinella, P. C., Panzer, S., and Reesink, H. W.
Published: 2011
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28. LO41: The development of a standardized provincial massive hemorrhage protocol with a built-in continuous quality improvement framework

Author: Yeh, C., primary, Cope, S., additional, Thompson, T., additional, McGilvray, S., additional, Petrosoniak, A., additional, Chin, V., additional, Karkouti, K., additional, Nathens, A., additional, Murto, K., additional, Beno, S., additional, McDonald, A., additional, Beckett, A., additional, Hanif, H., additional, Collins, A., additional, Nascimento, B., additional, Rizoli, S., additional, Sholzberg, M., additional, Pavenski, K., additional, and Callum, J., additional
Published: 2020
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29. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

Author: Sartelli, M, Kluger, Y, Ansaloni, L, Carlet, J, Brink, A, Hardcastle, T, Khanna, A, Chicom-Mefire, A, Rodriguez-Bano, J, Nathwani, D, Mendelson, M, Watkins, R, Pulcini, C, Beovic, B, May, A, Itani, K, Mazuski, J, Fry, D, Coccolini, F, Rasxa, K, Montravers, P, Eckmann, C, Abbo, L, Abubakar, S, Abu-Zidan, F, Adesunkanmi, A, Al-Hasan, M, Althani, A, Ticas, J, Ansari, S, Ansumana, R, Da Silva, A, Augustin, G, Bala, M, Balogh, Z, Baraket, O, Bassetti, M, Bellanova, G, Beltran, M, Ben-Ishay, O, Biffl, W, Boermeester, M, Brecher, S, Bueno, J, Cainzos, M, Cairns, K, Camacho-Ortiz, A, Ceresoli, M, Chandy, S, Cherry-Bukowiec, J, Cirocchi, R, Colak, E, Corcione, A, Cornely, O, Cortese, F, Cui, Y, Curcio, D, Damaskos, D, Dasx, K, Delibegovic, S, Demetrashvili, Z, De Simone, B, De Souza, H, De Waele, J, Dhingra, S, Diaz, J, Di Carlo, I, Di Marzo, F, Di Saverio, S, Dogjani, A, Dorj, G, Dortet, L, Duane, T, Dupont, H, Egiev, V, Eid, H, Elmangory, M, El-Sayed Marei, H, Enani, M, Escandon-Vargas, K, Faro, M, Ferrada, P, Foghetti, D, Foianini, E, Fraga, G, Frattima, S, Gandhi, C, Gattuso, G, Giamarellou, E, Ghnnam, W, Gkiokas, G, Girardis, M, Goff, D, Gomes, C, Gomi, H, Gronerth, R, Guirao, X, Guzman-Blanco, M, Haque, M, Hecker, A, Hell, M, Herzog, T, Hicks, L, Kafka-Ritsch, R, Kao, L, Kanj, S, Kaplan, L, Kapoor, G, Karamarkovic, A, Kashuk, J, Kenig, J, Khamis, F, Khokha, V, Kiguba, R, Kirkpatrick, A, Korner, H, Koike, K, Kok, K, Kon, K, Kong, V, Inaba, K, Ioannidis, O, Isik, A, Iskandar, K, Labbate, M, Labricciosa, F, Lagrou, K, Lagunes, L, Latifi, R, Lasithiotakis, K, Laxminarayan, R, Lee, J, Leone, M, Leppaniemi, A, Li, Y, Liang, S, Liau, K, Litvin, A, Loho, T, Lowman, W, Machain, G, Maier, R, Manzano-Nunez, R, Marinis, A, Marmorale, C, Martin-Loeches, I, Marwah, S, Maseda, E, Mcfarlane, M, De Melo, R, Melotti, M, Memish, Z, Mertz, D, Mesina, C, Menichetti, F, Mishra, S, Montori, G, Moore, E, Moore, F, Naidoo, N, Napolitano, L, Negoi, I, Nicolau, D, Nikolopoulos, I, Nord, C, Ofori-Asenso, R, Olaoye, I, Omari, A, Ordonez, C, Ouadii, M, Ouedraogo, A, Pagani, L, Paiva, J, Parreira, J, Pata, F, Pereira, J, Pereira, N, Petrosillo, N, Picetti, E, Pintar, T, Ponce-De-Leon, A, Popovski, Z, Poulakou, G, Preller, J, Guerrero, A, Pupelis, G, Quiodettis, M, Rawson, T, Reichert, M, Reinhart, K, Rems, M, Rello, J, Rizoli, S, Roberts, J, Rubio-Perez, I, Ruppe, E, Sakakushev, B, Sall, I, Kafil, H, Sanders, J, Sato, N, Sawyer, R, Scalea, T, Scibe, R, Scudeller, L, Lohse, H, Sganga, G, Shafiq, N, Shah, J, Spigaglia, P, Suroowan, S, Tsioutis, C, Sifri, C, Siribumrungwong, B, Sugrue, M, Talving, P, Tan, B, Tarasconi, A, Tascini, C, Tilsed, J, Timsit, J, Tumbarello, M, Trung, N, Ulrych, J, Uranues, S, Velmahos, G, Vereczkei, A, Viale, P, Estape, J, Viscoli, C, Wagenlehner, F, Wright, B, Xiao, Y, Yuan, K, Zachariah, S, Zahar, J, Mergulhao, P, Catena, F, Sartelli M., Kluger Y., Ansaloni L., Carlet J., Brink A., Hardcastle T. C., Khanna A., Chicom-Mefire A., Rodriguez-Bano J., Nathwani D., Mendelson M., Watkins R. R., Pulcini C., Beovic B., May A. K., Itani K. M. F., Mazuski J. E., Fry D. E., Coccolini F., Rasxa K., Montravers P., Eckmann C., Abbo L. M., Abubakar S., Abu-Zidan F. M., Adesunkanmi A. K., Al-Hasan M. N., Althani A. A., Ticas J. E. A., Ansari S., Ansumana R., Da Silva A. R. A., Augustin G., Bala M., Balogh Z. J., Baraket O., Bassetti M., Bellanova G., Beltran M. A., Ben-Ishay O., Biffl W. L., Boermeester M. A., Brecher S. M., Bueno J., Cainzos M. A., Cairns K., Camacho-Ortiz A., Ceresoli M., Chandy S. J., Cherry-Bukowiec J. R., Cirocchi R., Colak E., Corcione A., Cornely O. A., Cortese F., Cui Y., Curcio D., Damaskos D., Dasx K., Delibegovic S., Demetrashvili Z., De Simone B., De Souza H. P., De Waele J., Dhingra S., Diaz J. J., Di Carlo I., Di Marzo F., Di Saverio S., Dogjani A., Dorj G., Dortet L., Duane T. M., Dupont H., Egiev V. N., Eid H. O., Elmangory M., El-Sayed Marei H., Enani M. A., Escandon-Vargas K., Faro M. P., Ferrada P., Foghetti D., Foianini E., Fraga G. P., Frattima S., Gandhi C., Gattuso G., Giamarellou E., Ghnnam W., Gkiokas G., Girardis M., Goff D. A., Gomes C. A., Gomi H., Gronerth R. I. G., Guirao X., Guzman-Blanco M., Haque M., Hecker A., Hell M., Herzog T., Hicks L., Kafka-Ritsch R., Kao L. S., Kanj S. S., Kaplan L. J., Kapoor G., Karamarkovic A., Kashuk J., Kenig J., Khamis F., Khokha V., Kiguba R., Kirkpatrick A. W., Korner H., Koike K., Kok K. Y. Y., Kon K., Kong V., Inaba K., Ioannidis O., Isik A., Iskandar K., Labbate M., Labricciosa F. M., Lagrou K., Lagunes L., Latifi R., Lasithiotakis K., Laxminarayan R., Lee J. G., Leone M., Leppaniemi A., Li Y., Liang S. Y., Liau K. -H., Litvin A., Loho T., Lowman W., Machain G. M., Maier R. V., Manzano-Nunez R., Marinis A., Marmorale C., Martin-Loeches I., Marwah S., Maseda E., McFarlane M., De Melo R. B., Melotti M. R., Memish Z., Mertz D., Mesina C., Menichetti F., Mishra S. K., Montori G., Moore E. E., Moore F. A., Naidoo N., Napolitano L., Negoi I., Nicolau D. P., Nikolopoulos I., Nord C. E., Ofori-Asenso R., Olaoye I., Omari A. H., Ordonez C. A., Ouadii M., Ouedraogo A. -S., Pagani L., Paiva J. A., Parreira J. G., Pata F., Pereira J., Pereira N. R., Petrosillo N., Picetti E., Pintar T., Ponce-De-Leon A., Popovski Z., Poulakou G., Preller J., Guerrero A. P., Pupelis G., Quiodettis M., Rawson T. M., Reichert M., Reinhart K., Rems M., Rello J., Rizoli S., Roberts J., Rubio-Perez I., Ruppe E., Sakakushev B., Sall I., Kafil H. S., Sanders J., Sato N., Sawyer R. G., Scalea T., Scibe R., Scudeller L., Lohse H. S., Sganga G., Shafiq N., Shah J. N., Spigaglia P., Suroowan S., Tsioutis C., Sifri C. D., Siribumrungwong B., Sugrue M., Talving P., Tan B. K., Tarasconi A., Tascini C., Tilsed J., Timsit J. -F., Tumbarello M., Trung N. T., Ulrych J., Uranues S., Velmahos G., Vereczkei A. G., Viale P., Estape J. V., Viscoli C., Wagenlehner F., Wright B. J., Xiao Y., Yuan K. -C., Zachariah S. K., Zahar J. R., Mergulhao P., Catena F., Sartelli, M, Kluger, Y, Ansaloni, L, Carlet, J, Brink, A, Hardcastle, T, Khanna, A, Chicom-Mefire, A, Rodriguez-Bano, J, Nathwani, D, Mendelson, M, Watkins, R, Pulcini, C, Beovic, B, May, A, Itani, K, Mazuski, J, Fry, D, Coccolini, F, Rasxa, K, Montravers, P, Eckmann, C, Abbo, L, Abubakar, S, Abu-Zidan, F, Adesunkanmi, A, Al-Hasan, M, Althani, A, Ticas, J, Ansari, S, Ansumana, R, Da Silva, A, Augustin, G, Bala, M, Balogh, Z, Baraket, O, Bassetti, M, Bellanova, G, Beltran, M, Ben-Ishay, O, Biffl, W, Boermeester, M, Brecher, S, Bueno, J, Cainzos, M, Cairns, K, Camacho-Ortiz, A, Ceresoli, M, Chandy, S, Cherry-Bukowiec, J, Cirocchi, R, Colak, E, Corcione, A, Cornely, O, Cortese, F, Cui, Y, Curcio, D, Damaskos, D, Dasx, K, Delibegovic, S, Demetrashvili, Z, De Simone, B, De Souza, H, De Waele, J, Dhingra, S, Diaz, J, Di Carlo, I, Di Marzo, F, Di Saverio, S, Dogjani, A, Dorj, G, Dortet, L, Duane, T, Dupont, H, Egiev, V, Eid, H, Elmangory, M, El-Sayed Marei, H, Enani, M, Escandon-Vargas, K, Faro, M, Ferrada, P, Foghetti, D, Foianini, E, Fraga, G, Frattima, S, Gandhi, C, Gattuso, G, Giamarellou, E, Ghnnam, W, Gkiokas, G, Girardis, M, Goff, D, Gomes, C, Gomi, H, Gronerth, R, Guirao, X, Guzman-Blanco, M, Haque, M, Hecker, A, Hell, M, Herzog, T, Hicks, L, Kafka-Ritsch, R, Kao, L, Kanj, S, Kaplan, L, Kapoor, G, Karamarkovic, A, Kashuk, J, Kenig, J, Khamis, F, Khokha, V, Kiguba, R, Kirkpatrick, A, Korner, H, Koike, K, Kok, K, Kon, K, Kong, V, Inaba, K, Ioannidis, O, Isik, A, Iskandar, K, Labbate, M, Labricciosa, F, Lagrou, K, Lagunes, L, Latifi, R, Lasithiotakis, K, Laxminarayan, R, Lee, J, Leone, M, Leppaniemi, A, Li, Y, Liang, S, Liau, K, Litvin, A, Loho, T, Lowman, W, Machain, G, Maier, R, Manzano-Nunez, R, Marinis, A, Marmorale, C, Martin-Loeches, I, Marwah, S, Maseda, E, Mcfarlane, M, De Melo, R, Melotti, M, Memish, Z, Mertz, D, Mesina, C, Menichetti, F, Mishra, S, Montori, G, Moore, E, Moore, F, Naidoo, N, Napolitano, L, Negoi, I, Nicolau, D, Nikolopoulos, I, Nord, C, Ofori-Asenso, R, Olaoye, I, Omari, A, Ordonez, C, Ouadii, M, Ouedraogo, A, Pagani, L, Paiva, J, Parreira, J, Pata, F, Pereira, J, Pereira, N, Petrosillo, N, Picetti, E, Pintar, T, Ponce-De-Leon, A, Popovski, Z, Poulakou, G, Preller, J, Guerrero, A, Pupelis, G, Quiodettis, M, Rawson, T, Reichert, M, Reinhart, K, Rems, M, Rello, J, Rizoli, S, Roberts, J, Rubio-Perez, I, Ruppe, E, Sakakushev, B, Sall, I, Kafil, H, Sanders, J, Sato, N, Sawyer, R, Scalea, T, Scibe, R, Scudeller, L, Lohse, H, Sganga, G, Shafiq, N, Shah, J, Spigaglia, P, Suroowan, S, Tsioutis, C, Sifri, C, Siribumrungwong, B, Sugrue, M, Talving, P, Tan, B, Tarasconi, A, Tascini, C, Tilsed, J, Timsit, J, Tumbarello, M, Trung, N, Ulrych, J, Uranues, S, Velmahos, G, Vereczkei, A, Viale, P, Estape, J, Viscoli, C, Wagenlehner, F, Wright, B, Xiao, Y, Yuan, K, Zachariah, S, Zahar, J, Mergulhao, P, Catena, F, Sartelli M., Kluger Y., Ansaloni L., Carlet J., Brink A., Hardcastle T. C., Khanna A., Chicom-Mefire A., Rodriguez-Bano J., Nathwani D., Mendelson M., Watkins R. R., Pulcini C., Beovic B., May A. K., Itani K. M. F., Mazuski J. E., Fry D. E., Coccolini F., Rasxa K., Montravers P., Eckmann C., Abbo L. M., Abubakar S., Abu-Zidan F. M., Adesunkanmi A. K., Al-Hasan M. N., Althani A. A., Ticas J. E. A., Ansari S., Ansumana R., Da Silva A. R. A., Augustin G., Bala M., Balogh Z. J., Baraket O., Bassetti M., Bellanova G., Beltran M. A., Ben-Ishay O., Biffl W. L., Boermeester M. A., Brecher S. M., Bueno J., Cainzos M. A., Cairns K., Camacho-Ortiz A., Ceresoli M., Chandy S. J., Cherry-Bukowiec J. R., Cirocchi R., Colak E., Corcione A., Cornely O. A., Cortese F., Cui Y., Curcio D., Damaskos D., Dasx K., Delibegovic S., Demetrashvili Z., De Simone B., De Souza H. P., De Waele J., Dhingra S., Diaz J. J., Di Carlo I., Di Marzo F., Di Saverio S., Dogjani A., Dorj G., Dortet L., Duane T. M., Dupont H., Egiev V. N., Eid H. O., Elmangory M., El-Sayed Marei H., Enani M. A., Escandon-Vargas K., Faro M. P., Ferrada P., Foghetti D., Foianini E., Fraga G. P., Frattima S., Gandhi C., Gattuso G., Giamarellou E., Ghnnam W., Gkiokas G., Girardis M., Goff D. A., Gomes C. A., Gomi H., Gronerth R. I. G., Guirao X., Guzman-Blanco M., Haque M., Hecker A., Hell M., Herzog T., Hicks L., Kafka-Ritsch R., Kao L. S., Kanj S. S., Kaplan L. J., Kapoor G., Karamarkovic A., Kashuk J., Kenig J., Khamis F., Khokha V., Kiguba R., Kirkpatrick A. W., Korner H., Koike K., Kok K. Y. Y., Kon K., Kong V., Inaba K., Ioannidis O., Isik A., Iskandar K., Labbate M., Labricciosa F. M., Lagrou K., Lagunes L., Latifi R., Lasithiotakis K., Laxminarayan R., Lee J. G., Leone M., Leppaniemi A., Li Y., Liang S. Y., Liau K. -H., Litvin A., Loho T., Lowman W., Machain G. M., Maier R. V., Manzano-Nunez R., Marinis A., Marmorale C., Martin-Loeches I., Marwah S., Maseda E., McFarlane M., De Melo R. B., Melotti M. R., Memish Z., Mertz D., Mesina C., Menichetti F., Mishra S. K., Montori G., Moore E. E., Moore F. A., Naidoo N., Napolitano L., Negoi I., Nicolau D. P., Nikolopoulos I., Nord C. E., Ofori-Asenso R., Olaoye I., Omari A. H., Ordonez C. A., Ouadii M., Ouedraogo A. -S., Pagani L., Paiva J. A., Parreira J. G., Pata F., Pereira J., Pereira N. R., Petrosillo N., Picetti E., Pintar T., Ponce-De-Leon A., Popovski Z., Poulakou G., Preller J., Guerrero A. P., Pupelis G., Quiodettis M., Rawson T. M., Reichert M., Reinhart K., Rems M., Rello J., Rizoli S., Roberts J., Rubio-Perez I., Ruppe E., Sakakushev B., Sall I., Kafil H. S., Sanders J., Sato N., Sawyer R. G., Scalea T., Scibe R., Scudeller L., Lohse H. S., Sganga G., Shafiq N., Shah J. N., Spigaglia P., Suroowan S., Tsioutis C., Sifri C. D., Siribumrungwong B., Sugrue M., Talving P., Tan B. K., Tarasconi A., Tascini C., Tilsed J., Timsit J. -F., Tumbarello M., Trung N. T., Ulrych J., Uranues S., Velmahos G., Vereczkei A. G., Viale P., Estape J. V., Viscoli C., Wagenlehner F., Wright B. J., Xiao Y., Yuan K. -C., Zachariah S. K., Zahar J. R., Mergulhao P., and Catena F.
Abstract: This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages.
Published: 2017

30. Pelvic trauma: WSES classification and guidelines

Author: Coccolini, F, Stahel, P, Montori, G, Biffl, W, Horer, T, Catena, F, Kluger, Y, Moore, E, Peitzman, A, Ivatury, R, Coimbra, R, Fraga, G, Pereira, B, Rizoli, S, Kirkpatrick, A, Leppaniemi, A, Manfredi, R, Magnone, S, Chiara, O, Solaini, L, Ceresoli, M, Allievi, N, Arvieux, C, Velmahos, G, Balogh, Z, Naidoo, N, Weber, D, Abu-Zidan, F, Sartelli, M, Ansaloni, L, Coccolini F., Stahel P. F., Montori G., Biffl W., Horer T. M., Catena F., Kluger Y., Moore E. E., Peitzman A. B., Ivatury R., Coimbra R., Fraga G. P., Pereira B., Rizoli S., Kirkpatrick A., Leppaniemi A., Manfredi R., Magnone S., Chiara O., Solaini L., Ceresoli M., Allievi N., Arvieux C., Velmahos G., Balogh Z., Naidoo N., Weber D., Abu-Zidan F., Sartelli M., Ansaloni L., Coccolini, F, Stahel, P, Montori, G, Biffl, W, Horer, T, Catena, F, Kluger, Y, Moore, E, Peitzman, A, Ivatury, R, Coimbra, R, Fraga, G, Pereira, B, Rizoli, S, Kirkpatrick, A, Leppaniemi, A, Manfredi, R, Magnone, S, Chiara, O, Solaini, L, Ceresoli, M, Allievi, N, Arvieux, C, Velmahos, G, Balogh, Z, Naidoo, N, Weber, D, Abu-Zidan, F, Sartelli, M, Ansaloni, L, Coccolini F., Stahel P. F., Montori G., Biffl W., Horer T. M., Catena F., Kluger Y., Moore E. E., Peitzman A. B., Ivatury R., Coimbra R., Fraga G. P., Pereira B., Rizoli S., Kirkpatrick A., Leppaniemi A., Manfredi R., Magnone S., Chiara O., Solaini L., Ceresoli M., Allievi N., Arvieux C., Velmahos G., Balogh Z., Naidoo N., Weber D., Abu-Zidan F., Sartelli M., and Ansaloni L.
Abstract: Complex pelvic injuries are among the most dangerous and deadly trauma related lesions. Different classification systems exist, some are based on the mechanism of injury, some on anatomic patterns and some are focusing on the resulting instability requiring operative fixation. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic impairment of pelvic ring function and the associated injuries. The management of pelvic trauma patients aims definitively to restore the homeostasis and the normal physiopathology associated to the mechanical stability of the pelvic ring. Thus the management of pelvic trauma must be multidisciplinary and should be ultimately based on the physiology of the patient and the anatomy of the injury. This paper presents the World Society of Emergency Surgery (WSES) classification of pelvic trauma and the management Guidelines.
Published: 2017

31. The role of open abdomen in non-trauma patient: WSES Consensus Paper

Author: Coccolini, F, Montori, G, Ceresoli, M, Catena, F, Moore, E, Ivatury, R, Biffl, W, Peitzman, A, Coimbra, R, Rizoli, S, Kluger, Y, Abu-Zidan, F, Sartelli, M, Moya, M, Velmahos, G, Fraga, G, Pereira, B, Leppaniemi, A, Boermeester, M, Kirkpatrick, A, Maier, R, Bala, M, Sakakushev, B, Khokha, V, Malbrain, M, Agnoletti, V, Martin-Loeches, I, Sugrue, M, Saverio, S, Griffiths, E, Soreide, K, Mazuski, J, May, A, Montravers, P, Melotti, R, Pisano, M, Salvetti, F, Marchesi, G, Valetti, T, Scalea, T, Chiara, O, Kashuk, J, Ansaloni, L, Coccolini F., Montori G., Ceresoli M., Catena F., Moore E. E., Ivatury R., Biffl W., Peitzman A., Coimbra R., Rizoli S., Kluger Y., Abu-Zidan F. M., Sartelli M., Moya M. D., Velmahos G., Fraga G. P., Pereira B. M., Leppaniemi A., Boermeester M. A., Kirkpatrick A. W., Maier R., Bala M., Sakakushev B., Khokha V., Malbrain M., Agnoletti V., Martin-Loeches I., Sugrue M., Saverio S. D., Griffiths E., Soreide K., Mazuski J. E., May A. K., Montravers P., Melotti R. M., Pisano M., Salvetti F., Marchesi G., Valetti T. M., Scalea T., Chiara O., Kashuk J. L., Ansaloni L., Coccolini, F, Montori, G, Ceresoli, M, Catena, F, Moore, E, Ivatury, R, Biffl, W, Peitzman, A, Coimbra, R, Rizoli, S, Kluger, Y, Abu-Zidan, F, Sartelli, M, Moya, M, Velmahos, G, Fraga, G, Pereira, B, Leppaniemi, A, Boermeester, M, Kirkpatrick, A, Maier, R, Bala, M, Sakakushev, B, Khokha, V, Malbrain, M, Agnoletti, V, Martin-Loeches, I, Sugrue, M, Saverio, S, Griffiths, E, Soreide, K, Mazuski, J, May, A, Montravers, P, Melotti, R, Pisano, M, Salvetti, F, Marchesi, G, Valetti, T, Scalea, T, Chiara, O, Kashuk, J, Ansaloni, L, Coccolini F., Montori G., Ceresoli M., Catena F., Moore E. E., Ivatury R., Biffl W., Peitzman A., Coimbra R., Rizoli S., Kluger Y., Abu-Zidan F. M., Sartelli M., Moya M. D., Velmahos G., Fraga G. P., Pereira B. M., Leppaniemi A., Boermeester M. A., Kirkpatrick A. W., Maier R., Bala M., Sakakushev B., Khokha V., Malbrain M., Agnoletti V., Martin-Loeches I., Sugrue M., Saverio S. D., Griffiths E., Soreide K., Mazuski J. E., May A. K., Montravers P., Melotti R. M., Pisano M., Salvetti F., Marchesi G., Valetti T. M., Scalea T., Chiara O., Kashuk J. L., and Ansaloni L.
Abstract: The open abdomen (OA) is defined as intentional decision to leave the fascial edges of the abdomen un-approximated after laparotomy (laparostomy). The abdominal contents are potentially exposed and therefore must be protected with a temporary coverage, which is referred to as temporal abdominal closure (TAC). OA use remains widely debated with many specific details deserving detailed assessment and clarification. To date, in patients with intra-abdominal emergencies, the OA has not been formally endorsed for routine utilization; although, utilization is seemingly increasing. Therefore, the World Society of Emergency Surgery (WSES), Abdominal Compartment Society (WSACS) and the Donegal Research Academy united a worldwide group of experts in an international consensus conference to review and thereafter propose the basis for evidence-directed utilization of OA management in non-trauma emergency surgery and critically ill patients. In addition to utilization recommendations, questions with insufficient evidence urgently requiring future study were identified.
Published: 2017

32. Splenic trauma: WSES classification and guidelines for adult and pediatric patients

Author: Coccolini, F, Montori, G, Catena, F, Kluger, Y, Biffl, W, Moore, E, Reva, V, Bing, C, Bala, M, Fugazzola, P, Bahouth, H, Marzi, I, Velmahos, G, Ivatury, R, Soreide, K, Horer, T, ten Broek, R, Pereira, B, Fraga, G, Inaba, K, Kashuk, J, Parry, N, Masiakos, P, Mylonas, K, Kirkpatrick, A, Abu-Zidan, F, Gomes, C, Benatti, S, Naidoo, N, Salvetti, F, Maccatrozzo, S, Agnoletti, V, Gamberini, E, Solaini, L, Costanzo, A, Celotti, A, Tomasoni, M, Khokha, V, Arvieux, C, Napolitano, L, Handolin, L, Pisano, M, Magnone, S, Spain, D, de Moya, M, Davis, K, De Angelis, N, Leppaniemi, A, Ferrada, P, Latifi, R, Navarro, D, Otomo, Y, Coimbra, R, Maier, R, Moore, F, Rizoli, S, Sakakushev, B, Galante, J, Chiara, O, Cimbanassi, S, Mefire, A, Weber, D, Ceresoli, M, Peitzman, A, Wehlie, L, Sartelli, M, Di Saverio, S, Ansaloni, L, Coccolini F., Montori G., Catena F., Kluger Y., Biffl W., Moore E. E., Reva V., Bing C., Bala M., Fugazzola P., Bahouth H., Marzi I., Velmahos G., Ivatury R., Soreide K., Horer T., ten Broek R., Pereira B. M., Fraga G. P., Inaba K., Kashuk J., Parry N., Masiakos P. T., Mylonas K. S., Kirkpatrick A., Abu-Zidan F., Gomes C. A., Benatti S. V., Naidoo N., Salvetti F., Maccatrozzo S., Agnoletti V., Gamberini E., Solaini L., Costanzo A., Celotti A., Tomasoni M., Khokha V., Arvieux C., Napolitano L., Handolin L., Pisano M., Magnone S., Spain D. A., de Moya M., Davis K. A., De Angelis N., Leppaniemi A., Ferrada P., Latifi R., Navarro D. C., Otomo Y., Coimbra R., Maier R. V., Moore F., Rizoli S., Sakakushev B., Galante J. M., Chiara O., Cimbanassi S., Mefire A. C., Weber D., Ceresoli M., Peitzman A. B., Wehlie L., Sartelli M., Di Saverio S., Ansaloni L., Coccolini, F, Montori, G, Catena, F, Kluger, Y, Biffl, W, Moore, E, Reva, V, Bing, C, Bala, M, Fugazzola, P, Bahouth, H, Marzi, I, Velmahos, G, Ivatury, R, Soreide, K, Horer, T, ten Broek, R, Pereira, B, Fraga, G, Inaba, K, Kashuk, J, Parry, N, Masiakos, P, Mylonas, K, Kirkpatrick, A, Abu-Zidan, F, Gomes, C, Benatti, S, Naidoo, N, Salvetti, F, Maccatrozzo, S, Agnoletti, V, Gamberini, E, Solaini, L, Costanzo, A, Celotti, A, Tomasoni, M, Khokha, V, Arvieux, C, Napolitano, L, Handolin, L, Pisano, M, Magnone, S, Spain, D, de Moya, M, Davis, K, De Angelis, N, Leppaniemi, A, Ferrada, P, Latifi, R, Navarro, D, Otomo, Y, Coimbra, R, Maier, R, Moore, F, Rizoli, S, Sakakushev, B, Galante, J, Chiara, O, Cimbanassi, S, Mefire, A, Weber, D, Ceresoli, M, Peitzman, A, Wehlie, L, Sartelli, M, Di Saverio, S, Ansaloni, L, Coccolini F., Montori G., Catena F., Kluger Y., Biffl W., Moore E. E., Reva V., Bing C., Bala M., Fugazzola P., Bahouth H., Marzi I., Velmahos G., Ivatury R., Soreide K., Horer T., ten Broek R., Pereira B. M., Fraga G. P., Inaba K., Kashuk J., Parry N., Masiakos P. T., Mylonas K. S., Kirkpatrick A., Abu-Zidan F., Gomes C. A., Benatti S. V., Naidoo N., Salvetti F., Maccatrozzo S., Agnoletti V., Gamberini E., Solaini L., Costanzo A., Celotti A., Tomasoni M., Khokha V., Arvieux C., Napolitano L., Handolin L., Pisano M., Magnone S., Spain D. A., de Moya M., Davis K. A., De Angelis N., Leppaniemi A., Ferrada P., Latifi R., Navarro D. C., Otomo Y., Coimbra R., Maier R. V., Moore F., Rizoli S., Sakakushev B., Galante J. M., Chiara O., Cimbanassi S., Mefire A. C., Weber D., Ceresoli M., Peitzman A. B., Wehlie L., Sartelli M., Di Saverio S., and Ansaloni L.
Abstract: Spleen injuries are among the most frequent trauma-related injuries. At present, they are classified according to the anatomy of the injury. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic derangement, and the associated injuries. The management of splenic trauma patients aims to restore the homeostasis and the normal physiopathology especially considering the modern tools for bleeding management. Thus, the management of splenic trauma should be ultimately multidisciplinary and based on the physiology of the patient, the anatomy of the injury, and the associated lesions. Lastly, as the management of adults and children must be different, children should always be treated in dedicated pediatric trauma centers. In fact, the vast majority of pediatric patients with blunt splenic trauma can be managed non-operatively. This paper presents the World Society of Emergency Surgery (WSES) classification of splenic trauma and the management guidelines.
Published: 2017

33. The evidence for the use of recombinant factor VIIa in massive bleeding: development of a transfusion policy framework

Author: Moltzan, C. J., Anderson, D. A., Callum, J., Fremes, S., Hume, H., Mazer, C. D., Poon, M. C., Rivard, G., Rizoli, S., and Robinson, S.
Published: 2008

34. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project

Author: Blot, S. Antonelli, M. Arvaniti, K. Blot, K. Creagh-Brown, B. de Lange, D. De Waele, J. Deschepper, M. Dikmen, Y. Dimopoulos, G. Eckmann, C. Francois, G. Girardis, M. Koulenti, D. Labeau, S. Lipman, J. Lipovestky, F. Maseda, E. Montravers, P. Mikstacki, A. Paiva, J.-A. Pereyra, C. Rello, J. Timsit, J.-F. Vogelaers, D. Lamrous, A. Rezende-Neto, J. Cardenas, Y. Vymazal, T. Fjeldsoee-Nielsen, H. Kott, M. Kostoula, A. Javeri, Y. Einav, S. Makikado, L.D.U. Tomescu, D. Gritsan, A. Jovanovic, B. Venkatesan, K. Mirkovic, T. Creagh-Brown, B. Lamrous, A. Emmerich, M. Canale, M. Dietz, L.S. Ilutovich, S. Miñope, J.T.S. Silva, R.B. Montenegro, M.A. Martin, P. Saul, P. Chediack, V. Sutton, G. Couce, R. Balasini, C. Gonzalez, S. Lascar, F.M. Descotte, E.J. Gumiela, N.S. Pino, C.A. Cesio, C. Valgolio, E. Cunto, E. Dominguez, C. Nelson, N.F. Abegao, E.M. Pozo, N.C. Bianchi, L. Correger, E. Pastorino, M.L. Miyazaki, E.A. Pozo, N.C. Grubissich, N. Garcia, M. Bonetto, N. Quevedo, N.E. Gomez, C.D. Queti, F. Estevarena, L.G. Fernandez, R. Santolaya, I. Pozo, N.C. Grangeat, S.H. Doglia, J. Zakalik, G. Pellegrini, C. Lloria, M.M. Chacon, M.E. Fumale, M. Leguizamon, M. Hidalgo, I.B. Tiranti, R.J. Capponi, P. Tita, A. Cardonnet, L. Bettini, L. Ramos, A. Lovesio, L. Miranda, E.M. Farfan, A.B. Tolosa, C. Segura, L. Bellocchio, A. Alvarez, B. Manzur, A. Lujan, R. Fernandez, N. Scarone, N. Zazu, A. Groh, C. Fletcher, J. Smith, J. Azad, R. Chavan, N. Wong, H. Kol, M. Campbell, L. Starr, T. Roberts, B. Wibrow, B. Warhurst, T. Chinthamuneedi, M. Ferney, B.B. Simon, M. De Backer, D. Wittebole, X. De Bels, D. Collin, V. Dams, K. Jorens, P. Dubois, J. Gunst, J. Haentjens, L. De Schryver, N. Dugernier, T. Rezende-Neto, J. Rizoli, S. Santillan, P. Han, Y. Biskup, E. Qu, C. Li, X. Yu, T. Weihua, L. Molano-Franco, D. Rojas, J. Oviedo, J.M.P. Pinilla, D. Cardenas, Y. Celis, E. Arias, M. Vukovic, A. Vudrag, M. Belavic, M. Zunic, J. Kuharic, J. Kricka, I.B. Filipovic-Grcic, I. Tomasevic, B. Obraz, M. Bodulica, B. Dohnal, M. Malaska, J. Kratochvil, M. Satinsky, I. Schwarz, P. Kos, Z. Blahut, L. Maca, J. Protus, M. Kieslichová, E. Nielsen, L.G. Krogh, B.M. Rivadeneira, F. Morales, F. Mora, J. Orozco, A.S. MorochoTutillo, D.R. Vargas, N.R. Yepez, E.S. Villamagua, B. Alsisi, A. Fahmy, A. Dupont, H. Lasocki, S. Paugam-Burtz, C. Foucrier, A. Nica, A. Barjon, G. Mallat, J. Marcotte, G. Leone, M. Duclos, G. Burtin, P. Atchade, E. Mahjoub, Y. Misset, B. Timsit, J.-F. Dupuis, C. Veber, B. Debarre, M. Collange, O. Pottecher, J. Hecketsweiler, S. Fromentin, M. Tesnière, A. Koch, C. Sander, M. Kott, M. Elke, G. Wrigge, H. Simon, P. Chalkiadaki, A. Tzanidakis, C. Pneumatikos, I. Sertaridou, E. Mastora, Z. Pantazopoulos, I. Papanikolaou, M. Papavasilopoulou, T. Floros, J. Kolonia, V. Diakaki, C. Rallis, M. Paridou, A. Kalogeromitros, A. Romanou, V. Nikolaou, C. Kounougeri, K. Tsigou, E. Psallida, V. Karampela, N. Mandragos, K. Kontoudaki, E. Pentheroudaki, A. Farazi-Chongouki, C. Karakosta, A. Chouris, I. Radu, V. Malliotakis, P. Kokkini, S. Charalambous, E. Kyritsi, A. Koulouras, V. Papathanakos, G. Nagky, E. Lampiri, C. Tsimpoukas, F. Sarakatsanos, I. Georgakopoulos, P. Ravani, I. Prekates, A. Sakellaridis, K. Christopoulos, C. Vrettou, E. Stokkos, K. Pentari, A. Marmanidou, K. Kydona, C. Tsoumaropoulos, G. Bitzani, M. Kontou, P. Voudouris, A. Elli-Nikki Flioni Antypa, E. Chasou, E. Anisoglou, S. Papageorgiou, E. Paraforou, T. Tsioka, A. Karathanou, A. Vakalos, A. Shah, B. Thakkar, C. Jain, N. Gurjar, M. Baronia, A. Sathe, P. Kulkarni, S. Paul, C. Paul, J. Masjedi, M. Nikandish, R. Zand, F. Sabetian, G. Mahmoodpoor, A. Hashemian, S.M. Bala, M. Flocco, R. Torrente, S. Pota, V. Spadaro, S. Volta, C. Serafini, G. Boraso, S. Tiberio, I. Cortegiani, A. Misseri, G. Barbagallo, M. Nicolotti, D. Forfori, F. Corradi, F. De Pascale, G. Pelagalli, L. Brazzi, L. Vittone, F.G. Russo, A. Simion, D. Cotoia, A. Cinnella, G. Toppin, P. Johnson-Jackson, R. Hayashi, Y. Yamamoto, R. Yasuda, H. Kishihara, Y. Shiotsuka, J. Sanchez-Hurtado, L.A. Tejeda-Huezo, B. Gorordo, L. Ñamendys-Silva, S.A. Garcia-Guillen, F.J. Martinez, M. Romero-Meja, E. Colorado-Dominguez, E. van den Oever, H. Kalff, K.M. Vermeijden, W. Cornet, A.D. Beck, O. Cimic, N. Dormans, T. Bormans, L. Bakker, J. Van Duijn, D. Bosman, G. Vos, P. Haas, L. Henein, A. Miranda, A.M. Makikado, L.D.U. Malca, G.E.G. Arroyo-Sanchez, A. Misiewska-Kaczur, A. Akinyi, F. Czuczwar, M. Luczak, K. Sulkowski, W. Tamowicz, B. Swit, B. Baranowski, B. Smuszkiewicz, P. Trojanowska, I. Rzymski, S. Sawinski, M. Trosiak, M. Mikaszewska-Sokolewicz, M. Alves, R. Leal, D. Krystopchuk, A. Mendonca, P.M.H. Pereira, R.A. de Carvalho, M.R.L.M. Candeias, C. Molinos, E. Ferreira, A. Castro, G. Pereira, J.-M. Santos, L. Ferreira, A. Pascoalinho, D. Ribeiro, R. Domingos, G. Gomes, P. Nora, D. Costa, R.P. Santos, A. Alsheikhly, A.S. Tomescu, D. Popescu, M. Grigoras, I. Patrascanu, E. Zabolotskikh, I. Musaeva, T. Gaigolnik, D. Kulabukhov, V. Belskiy, V. Zubareva, N. Tribulev, M. Abdelsalam, A. Aldarsani, A. Al-Khalid, M. Almekhlafi, G. Mandourah, Y. Jovanovic, B. Doklestic, K. Velickovic, J. Velickovic, D. Jankovic, R. Vukovic, A. Skoric-Jokic, S. Radovanovic, D. Richards, G. Alli, A. del Carmen Cordoba Nielfa, M. Iniesta, R.S. Martínez, A.B.-C. Bernedo, C.G. Gil, S.A.P. Nuvials, X. Garcia, J.G. Peña, J.M.G. Jimenez, R. Herrera, L. Barrachina, L.G. Monzon, I.C. Redondo, F.J. Villazala, R. Zapata, D.F.M. Lopez, I.M.V. Moreno-Gonzalez, G. Lopez-Delgado, J.C. Marin, J.S. Sanchez-Zamora, P. Vidal, M.V. González, J.F. Salinas, I. Hermosa, C. Martinez-Sagasti, F. Domingo-Marín, S. Victorino, J.A. Garcia-Alvarez, R. Calleja, P.L.-A. de la Torre-Prados, M.-V. Vidal-Cortes, P. del Río-Carbajo, L. Izura, J. Minguez, V. Alvarez, J.T. Prous, A.P. Paz, D. Roche-Campo, F. Aguilar, G. Belda, J. Rico-Feijoo, J. Aldecoa, C. Zalba-Etayo, B. Lang, M. Dullenkopf, A. Trongtrakul, K. Chtsomkasem, A. Akbas, T. Unal, M.N. Ozcelik, M. Gumus, A. Ramazanoglu, A. Memis, D. Mehmet, I. Urkmez, S. Ozgultekin, A. Demirkiran, O. Aslan, N.A. Kizilaslan, D. Kahveci, F. Ünlü, N. Ozkan, Z. Kaye, C. Jansen, J. O’Neill, O. Nutt, C. Jha, R. Hooker, N. Grecu, I. Petridou, C. Shyamsundar, M. McNamee, L. Trinder, J. Hagan, S. Kelly, C. Silversides, J. Groba, C.B. Boyd, O. Bhowmick, K. Humphreys, S. Summers, C. Polgarova, P. Margarson, M. Dickens, J. Pearson, S. Chinery, E. Hemmings, N. O’Kane, S. Austin, P. Cole, S. Plowright, C. Box, R. Wright, C. Young, L. Montague, L. Parker, R. Morton, B. Ostermann, M. Bilinska, J. Rose, B.O. Reece-Anthony, R. Ryan, C. Hamilton, M. Hopkins, P. Wendon, J. Brescia, G. Ijaz, N. Wood, J. George, M. Toth-Tarsoly, P. Yates, B. Armstrong, M. Scott, C. Boyd, C. Szakmany, T. Rees, D. Pulak, P. Coggon, M. Saha, B. Kent, L. Gibson, B. Camsooksai, J. Reschreiter, H. Morgan, P. Sangaralingham, S. Lowe, A. Vondras, P. Jamadarkhana, S. Cruz, C. Bhandary, R. Hersey, P. Furneval, J. Innes, R. Doble, P. Attwood, B. Parsons, P. Page, V. Zhao, X. Grecu, I. Dalton, J. Hegazy, M. Awad, Y. Naylor, D. Naylor, A. Lee, S. Brevard, S. Davis, N. the Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine
Abstract: Purpose: To describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression (infection, sepsis, and septic shock). Methods: We performed a multicenter (n = 309), observational, epidemiological study including adult ICU patients diagnosed with intra-abdominal infection. Risk factors for mortality were assessed by logistic regression analysis. Results: The cohort included 2621 patients. Setting of infection acquisition was community-acquired in 31.6%, early onset hospital-acquired in 25%, and late-onset hospital-acquired in 43.4% of patients. Overall prevalence of antimicrobial resistance was 26.3% and difficult-to-treat resistant Gram-negative bacteria 4.3%, with great variation according to geographic region. No difference in prevalence of antimicrobial resistance was observed according to setting of infection acquisition. Overall mortality was 29.1%. Independent risk factors for mortality included late-onset hospital-acquired infection, diffuse peritonitis, sepsis, septic shock, older age, malnutrition, liver failure, congestive heart failure, antimicrobial resistance (either methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Gram-negative bacteria, or carbapenem-resistant Gram-negative bacteria) and source control failure evidenced by either the need for surgical revision or persistent inflammation. Conclusion: This multinational, heterogeneous cohort of ICU patients with intra-abdominal infection revealed that setting of infection acquisition, anatomical disruption, and severity of disease expression are disease-specific phenotypic characteristics associated with outcome, irrespective of the type of infection. Antimicrobial resistance is equally common in community-acquired as in hospital-acquired infection. © 2019, The Author(s).
Published: 2019

35. The Immunological Effects of Hypertonic Saline

Author: Rizoli, S. B., primary, Rotstein, O. D., additional, and Sibbald, W. J., additional
Published: 2002
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36. WSES consensus conference guidelines: monitoring and management of severe adult traumatic brain injury patients with polytrauma in the first 24 hours

Author: Picetti, E, Rossi, S, Abu-Zidan, F, Ansaloni, L, Armonda, R, Baiocchi, G, Bala, M, Balogh, Z, Berardino, M, Biffl, W, Bouzat, P, Buki, A, Ceresoli, M, Chesnut, R, Chiara, O, Citerio, G, Coccolini, F, Coimbra, R, Di Saverio, S, Fraga, G, Gupta, D, Helbok, R, Hutchinson, P, Kirkpatrick, A, Kinoshita, T, Kluger, Y, Leppaniemi, A, Maas, A, Maier, R, Minardi, F, Moore, E, Myburgh, J, Okonkwo, D, Otomo, Y, Rizoli, S, Rubiano, A, Sahuquillo, J, Sartelli, M, Scalea, T, Servadei, F, Stahel, P, Stocchetti, N, Taccone, F, Tonetti, T, Velmahos, G, Weber, D, Catena, F, Picetti, Edoardo, Rossi, Sandra, Abu-Zidan, Fikri M., Ansaloni, Luca, Armonda, Rocco, Baiocchi, Gian Luca, Bala, Miklosh, Balogh, Zsolt J., Berardino, Maurizio, Biffl, Walter L., Bouzat, Pierre, Buki, Andras, Ceresoli, Marco, Chesnut, Randall M., Chiara, Osvaldo, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Di Saverio, Salomone, Fraga, Gustavo P., Gupta, Deepak, Helbok, Raimund, Hutchinson, Peter J., Kirkpatrick, Andrew W., Kinoshita, Takahiro, Kluger, Yoram, Leppaniemi, Ari, Maas, Andrew I. R., Maier, Ronald V., Minardi, Francesco, Moore, Ernest E., Myburgh, John A., Okonkwo, David O., Otomo, Yasuhiro, Rizoli, Sandro, Rubiano, Andres M., Sahuquillo, Juan, Sartelli, Massimo, Scalea, Thomas M., Servadei, Franco, Stahel, Philip F., Stocchetti, Nino, Taccone, Fabio S., Tonetti, Tommaso, Velmahos, George, Weber, Dieter, Catena, Fausto, Picetti, E, Rossi, S, Abu-Zidan, F, Ansaloni, L, Armonda, R, Baiocchi, G, Bala, M, Balogh, Z, Berardino, M, Biffl, W, Bouzat, P, Buki, A, Ceresoli, M, Chesnut, R, Chiara, O, Citerio, G, Coccolini, F, Coimbra, R, Di Saverio, S, Fraga, G, Gupta, D, Helbok, R, Hutchinson, P, Kirkpatrick, A, Kinoshita, T, Kluger, Y, Leppaniemi, A, Maas, A, Maier, R, Minardi, F, Moore, E, Myburgh, J, Okonkwo, D, Otomo, Y, Rizoli, S, Rubiano, A, Sahuquillo, J, Sartelli, M, Scalea, T, Servadei, F, Stahel, P, Stocchetti, N, Taccone, F, Tonetti, T, Velmahos, G, Weber, D, Catena, F, Picetti, Edoardo, Rossi, Sandra, Abu-Zidan, Fikri M., Ansaloni, Luca, Armonda, Rocco, Baiocchi, Gian Luca, Bala, Miklosh, Balogh, Zsolt J., Berardino, Maurizio, Biffl, Walter L., Bouzat, Pierre, Buki, Andras, Ceresoli, Marco, Chesnut, Randall M., Chiara, Osvaldo, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Di Saverio, Salomone, Fraga, Gustavo P., Gupta, Deepak, Helbok, Raimund, Hutchinson, Peter J., Kirkpatrick, Andrew W., Kinoshita, Takahiro, Kluger, Yoram, Leppaniemi, Ari, Maas, Andrew I. R., Maier, Ronald V., Minardi, Francesco, Moore, Ernest E., Myburgh, John A., Okonkwo, David O., Otomo, Yasuhiro, Rizoli, Sandro, Rubiano, Andres M., Sahuquillo, Juan, Sartelli, Massimo, Scalea, Thomas M., Servadei, Franco, Stahel, Philip F., Stocchetti, Nino, Taccone, Fabio S., Tonetti, Tommaso, Velmahos, George, Weber, Dieter, and Catena, Fausto
Abstract: The acute phase management of patients with severe traumatic brain injury (TBI) and polytrauma represents a major challenge. Guidelines for the care of these complex patients are lacking, and worldwide variability in clinical practice has been documented in recent studies. Consequently, the World Society of Emergency Surgery (WSES) decided to organize an international consensus conference regarding the monitoring and management of severe adult TBI polytrauma patients during the first 24 hours after injury. A modified Delphi approach was adopted, with an agreement cut-off of 70%. Forty experts in this field (emergency surgeons, neurosurgeons, and intensivists) participated in the online consensus process. Sixteen recommendations were generated, with the aim of promoting rational care in this difficult setting
Published: 2019

37. Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

Author: Sartelli, M., Weber, D. G., Ruppé, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, J. L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, M. A., Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Che Jusoh, A., Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzmán-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., Mcfarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Júnior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., Viale, P., Sartelli, M., Weber, D. G., Ruppé, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, J. L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, M. A., Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Che Jusoh, A., Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzmán-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., Mcfarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Júnior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., and Viale, P.
Subjects: Settore MED/18 - CHIRURGIA GENERALE, Surgery, Emergency Medicine
Published: 2017

38. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

Author: Broek, R.P.G ten, Krielen, P., Saverio, S. Di, Coccolini, F., Biffl, W.L., Ansaloni, L., Velmahos, G.C., Sartelli, M., Fraga, G.P., Kelly, M.D., Moore, F.A., Peitzman, A.B., Leppaniemi, A., Moore, E.E., Jeekel, J., Kluger, Y., Sugrue, M., Balogh, Z.J., Bendinelli, C., Civil, I., Coimbra, R., Moya, M., Ferrada, P., Inaba, K., Ivatury, R., Latifi, R., Kashuk, J.L., Kirkpatrick, A.W., Maier, R., Rizoli, S., Sakakushev, B., Scalea, T., Soreide, K., Weber, D., Wani, I., Abu-Zidan, F.M., De'Angelis, N., Piscioneri, F., Galante, J.M., Catena, F., Goor, H. van, Broek, R.P.G ten, Krielen, P., Saverio, S. Di, Coccolini, F., Biffl, W.L., Ansaloni, L., Velmahos, G.C., Sartelli, M., Fraga, G.P., Kelly, M.D., Moore, F.A., Peitzman, A.B., Leppaniemi, A., Moore, E.E., Jeekel, J., Kluger, Y., Sugrue, M., Balogh, Z.J., Bendinelli, C., Civil, I., Coimbra, R., Moya, M., Ferrada, P., Inaba, K., Ivatury, R., Latifi, R., Kashuk, J.L., Kirkpatrick, A.W., Maier, R., Rizoli, S., Sakakushev, B., Scalea, T., Soreide, K., Weber, D., Wani, I., Abu-Zidan, F.M., De'Angelis, N., Piscioneri, F., Galante, J.M., Catena, F., and Goor, H. van
Abstract: Contains fulltext : 194580.pdf (publisher's version ) (Open Access), Background: Adhesive small bowel obstruction (ASBO) is a common surgical emergency, causing high morbidity and even some mortality. The adhesions causing such bowel obstructions are typically the footprints of previous abdominal surgical procedures. The present paper presents a revised version of the Bologna guidelines to evidence-based diagnosis and treatment of ASBO. The working group has added paragraphs on prevention of ASBO and special patient groups. Methods: The guideline was written under the auspices of the World Society of Emergency Surgery by the ASBO working group. A systematic literature search was performed prior to the update of the guidelines to identify relevant new papers on epidemiology, diagnosis, and treatment of ASBO. Literature was critically appraised according to an evidence-based guideline development method. Final recommendations were approved by the workgroup, taking into account the level of evidence of the conclusion. Recommendations: Adhesion formation might be reduced by minimally invasive surgical techniques and the use of adhesion barriers. Non-operative treatment is effective in most patients with ASBO. Contraindications for non-operative treatment include peritonitis, strangulation, and ischemia. When the adhesive etiology of obstruction is unsure, or when contraindications for non-operative management might be present, CT is the diagnostic technique of choice. The principles of non-operative treatment are nil per os, naso-gastric, or long-tube decompression, and intravenous supplementation with fluids and electrolytes. When operative treatment is required, a laparoscopic approach may be beneficial for selected cases of simple ASBO.Younger patients have a higher lifetime risk for recurrent ASBO and might therefore benefit from application of adhesion barriers as both primary and secondary prevention. Discussion: This guideline presents recommendations that can be used by surgeons who treat patients with ASBO. Scientific evidence f
Published: 2018

39. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO)

Author: Broek, R.P. (R.) ten, Krielen, P. (Pepijn), Di Saverio, S. (Salomone), Coccolini, F. (Federico), Biffl, W.L. (Walter), Ansaloni, L. (Luca), Velmahos, G.C. (George ), Sartelli, M. (Massimo), Fraga, G.P. (Gustavo), Kelly, M.D. (Michael D.), Moore, F.A. (Frederick), Peitzman, A.B. (Andrew), Leppaniemi, A. (Ari), Moore, E.E. (Ernest), Jeekel, J. (Hans), Kluger, Y. (Yoram), Sugrue, M. (Michael), Balogh, Z.J. (Zsolt J.), Bendinelli, C. (Cino), Civil, I. (Ian), Coimbra, R. (Raul), De Moya, M. (Mark), Ferrada, P. (Paula), Inaba, K. (Kenji), Ivatury, R. (Rao), Latifi, R. (Rifat), Kashuk, J.L. (Jeffry L.), Kirkpatrick, A.W. (Andrew W.), Maier, R. (Ron), Rizoli, S. (Sandro), Sakakushev, B. (Boris), Scalea, T. (Thomas), Søreide, K. (Kjetil), Weber, D. (Dieter), Wani, I. (Imtiaz), Abu-Zidan, F.M. (Fikri M.), De'Angelis, N. (Nicola), Piscioneri, F. (Frank), Galante, J.M. (Joseph M.), Catena, F. (Fausto), Goor, H. (Harry) van, Broek, R.P. (R.) ten, Krielen, P. (Pepijn), Di Saverio, S. (Salomone), Coccolini, F. (Federico), Biffl, W.L. (Walter), Ansaloni, L. (Luca), Velmahos, G.C. (George ), Sartelli, M. (Massimo), Fraga, G.P. (Gustavo), Kelly, M.D. (Michael D.), Moore, F.A. (Frederick), Peitzman, A.B. (Andrew), Leppaniemi, A. (Ari), Moore, E.E. (Ernest), Jeekel, J. (Hans), Kluger, Y. (Yoram), Sugrue, M. (Michael), Balogh, Z.J. (Zsolt J.), Bendinelli, C. (Cino), Civil, I. (Ian), Coimbra, R. (Raul), De Moya, M. (Mark), Ferrada, P. (Paula), Inaba, K. (Kenji), Ivatury, R. (Rao), Latifi, R. (Rifat), Kashuk, J.L. (Jeffry L.), Kirkpatrick, A.W. (Andrew W.), Maier, R. (Ron), Rizoli, S. (Sandro), Sakakushev, B. (Boris), Scalea, T. (Thomas), Søreide, K. (Kjetil), Weber, D. (Dieter), Wani, I. (Imtiaz), Abu-Zidan, F.M. (Fikri M.), De'Angelis, N. (Nicola), Piscioneri, F. (Frank), Galante, J.M. (Joseph M.), Catena, F. (Fausto), and Goor, H. (Harry) van
Abstract: Background: Adhesive small bowel obstruction (ASBO) is a common surgical emergency, causing high morbidity and even some mortality. The adhesions causing such bowel obstructions are typically the footprints of previous abdominal surgical procedures. The present paper presents a revised version of the Bologna guidelines to evidence-based diagnosis and treatment of ASBO. The working group has added paragraphs on prevention of ASBO and special patient groups. Methods: The guideline was written under the auspices of the World Society of Emergency Surgery by the ASBO working group. A systematic literature search was performed prior to the update of the guidelines to identify relevant new papers on epidemiology, diagnosis, and treatment of ASBO. Literature was critically appraised according to an evidence-based guideline development method. Final recommendations were approved by the workgroup, taking into account the level of evidence of the conclusion. Recommendations: Adhesion formation might be reduced by minimally invasive surgical techniques and the use of adhesion barriers. Non-operative treatment is effective in most patients with ASBO. Contraindications for non-operative treatment include peritonitis, strangulation, and ischemia. When the adhesive etiology of obstruction is unsure, or when contraindications for non-operative management might be present, CT is the diagnostic technique of choice. The principles of non-operative treatment are nil per os, naso-gastric, or long-tube decompression, and intravenous supplementation with fluids and electrolytes. When operative treatment is required, a laparoscopic approach may be beneficial for selected cases of simple ASBO. Younger patients have a higher lifetime risk for recurrent ASBO and might therefore benefit from application of adhesion barriers as both primary and secondary prevention. Discussion: This guideline presents recommendations that can be used by surgeons who treat patients with ASBO. Scientific evidence
Published: 2018
Full Text: View/download PDF

40. Harmful or physiologic: Diagnosing fibrinolysis shutdown in a trauma cohort with rotational thromboelastometry

Author: Gomez-Builes, J, Acuna, S, Nascimento, B, Madotto, F, Rizoli, S, Gomez-Builes, J Carolina, Acuna, Sergio A, Nascimento, Bartolomeu, Madotto, Fabiana, Rizoli, Sandro B, Gomez-Builes, J, Acuna, S, Nascimento, B, Madotto, F, Rizoli, S, Gomez-Builes, J Carolina, Acuna, Sergio A, Nascimento, Bartolomeu, Madotto, Fabiana, and Rizoli, Sandro B
Abstract: BACKGROUND: Despite its central role in early trauma coagulopathy, abnormal fibrinolysis continues to be poorly understood. Excessive fibrinolysis is a known contributor to mortality. Recent studies with thromboelastography (TEG) suggest decreased fibrinolysis (or shutdown) may be just as harmful. Considering the broad use of 2 different viscoelastic assays, which are not interchangeable, we proposed for the first time to define and characterize fibrinolysis shutdown using rotational thromboelastometry (ROTEM). METHODS: Retrospective cohort study of severely injured patients with admission ROTEM. Shutdown was defined by the best Youden index value of the maximum lysis. Fibrinolysis phenotypes were physiologic, hyperfibrinolysis, and shutdown. Multivariable logistic regression evaluated association between Injury Severity Score and the fibrinolysis phenotypes, and the association among shutdown phenotype with mortality, blood transfusion, and thrombotic events. RESULTS: Five hundred fifty patients were included. Maximum lysis <3.5% was selected to define shutdown. Predominant phenotype was physiologic (70.7%), followed by shutdown (25.6%) and hyperfibrinolysis (3.6%). Shutdown patients had higher Injury Severity Score, lower base excess, and required more transfusions than physiologic group. Shutdown was associated with acidosis (base excess: odds ratio [OR] for a 1 mEq/L increase, 0.93; 95% confidence interval [CI], 0.88-0.98; P = .0094) and the combination of clotting derangements, higher clot firmness (maximum clot formation: OR for a 2 mm increase, 1.8; 95% CI, 1.5-2.27; P < .0001), lower fibrinogen (OR for a 0.5 g/dL decrease, 1.47; 95% CI, 1.18-1.84; P = .0006), and poor clot formation dynamics (clot formation time: OR for a 5 seconds increase, 1.25; 95% CI, 1.15-1.36; P < .0001). Fibrinolysis shutdown was not independently associated with mortality (OR, 0.61; 95% CI, 0.28-1.33; P = .21), massive transfusion (OR, 2.14; 95% CI, 0.79-5.74; P = .1308), or thrombot
Published: 2018

41. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

Author: ten Broek, RPG, Krielen, P, Di Saverio, S, Coccolini, F, Biffl, WL, Ansaloni, L, Velmahos, GC, Sartelli, M, Fraga, GP, Kelly, MD, Moore, FA, Peitzman, AB, Leppaniemi, A, Moore, EE, Jeekel, J (Hans), Kluger, Y, Sugrue, M, Balogh, Z J, Bendinelli, C, Civil, I, Coimbra, R, De Moya, M, Ferrada, P, Inaba, K, Ivatury, R, Latifi, R, Kashuk, JL, Kirkpatrick, AW, Maier, R, Rizoli, S, Sakakushev, B, Scalea, T, Soreide, K, Weber, D, Wani, I, Abu-Zidan, FM, De'Angelis, N, Piscioneri, F, Galante, JM, Catena, F, van Goor, H, ten Broek, RPG, Krielen, P, Di Saverio, S, Coccolini, F, Biffl, WL, Ansaloni, L, Velmahos, GC, Sartelli, M, Fraga, GP, Kelly, MD, Moore, FA, Peitzman, AB, Leppaniemi, A, Moore, EE, Jeekel, J (Hans), Kluger, Y, Sugrue, M, Balogh, Z J, Bendinelli, C, Civil, I, Coimbra, R, De Moya, M, Ferrada, P, Inaba, K, Ivatury, R, Latifi, R, Kashuk, JL, Kirkpatrick, AW, Maier, R, Rizoli, S, Sakakushev, B, Scalea, T, Soreide, K, Weber, D, Wani, I, Abu-Zidan, FM, De'Angelis, N, Piscioneri, F, Galante, JM, Catena, F, and van Goor, H
Published: 2018

42. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) (vol 11, 33, 2016)

Author: Sartelli, M., Weber, D. G., Ruppe, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, Anna Maria, Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Jusoh, A. Che, Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzman-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., McFarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Junior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., Van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., Viale, P., Universita 'La Sapienza' Roma (Istituto CNR), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Universidade de Aveiro, Laboratoire matériaux et microélectronique de Provence (L2MP), Université Paul Cézanne - Aix-Marseille 3-Université de Provence - Aix-Marseille 1-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Côte d'Ivoire, Réseau International des Instituts Pasteur (RIIP), National Defence University of Malaysia [Kuala Lumpur], Max Planck Institute for the Physics of Complex Systems (MPI-PKS), Max-Planck-Gesellschaft, Center for Plant Molecular Biology, Plant Physiology, and Biophysical Chemistry, University of Tübingen, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Dipartimento di Fisica 'Giuseppe Occhialini' = Department of Physics 'Giuseppe Occhialini' [Milano-Bicocca], Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Atmospheric and Environmental Research, Inc. (AER), Zhejiang University, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), and COMBE, Isabelle
Subjects: [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Carbapenems, Antimicrobial Resistance, Invasive Candidiasis, Methicillin Resistant Staphylococcus Aureus, Tigecycline, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: International audience; Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance.The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria.An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2017

43. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

Author: Sartelli, M. Kluger, Y. Ansaloni, L. Carlet, J. Brink, A. Hardcastle, T.C. Khanna, A. Chicom-Mefire, A. Rodríguez-Baño, J. Nathwani, D. Mendelson, M. Watkins, R.R. Pulcini, C. Beović, B. May, A.K. Itani, K.M.F. Mazuski, J.E. Fry, D.E. Coccolini, F. Rasxa, K. Montravers, P. Eckmann, C. Abbo, L.M. Abubakar, S. Abu-Zidan, F.M. Adesunkanmi, A.K. Al-Hasan, M.N. Althani, A.A. Ticas, J.E.A. Ansari, S. Ansumana, R. Da Silva, A.R.A. Augustin, G. Bala, M. Balogh, Z.J. Baraket, O. Bassetti, M. Bellanova, G. Beltran, M.A. Ben-Ishay, O. Biffl, W.L. Boermeester, M.A. Brecher, S.M. Bueno, J. Cainzos, M.A. Cairns, K. Camacho-Ortiz, A. Ceresoli, M. Chandy, S.J. Cherry-Bukowiec, J.R. Cirocchi, R. Colak, E. Corcione, A. Cornely, O.A. Cortese, F. Cui, Y. Curcio, D. Damaskos, D. Dasx, K. Delibegovic, S. Demetrashvili, Z. De Simone, B. De Souza, H.P. De Waele, J. Dhingra, S. Diaz, J.J. Di Carlo, I. Di Marzo, F. Di Saverio, S. Dogjani, A. Dorj, G. Dortet, L. Duane, T.M. Dupont, H. Egiev, V.N. Eid, H.O. Elmangory, M. El-Sayed Marei, H. Enani, M.A. Escandón-Vargas, K. Faro, M.P., Jr. Ferrada, P. Foghetti, D. Foianini, E. Fraga, G.P. Frattima, S. Gandhi, C. Gattuso, G. Giamarellou, E. Ghnnam, W. Gkiokas, G. Girardis, M. Goff, D.A. Gomes, C.A. Gomi, H. Gronerth, R.I.G. Guirao, X. Guzman-Blanco, M. Haque, M. Hecker, A. Hell, M. Herzog, T. Hicks, L. Kafka-Ritsch, R. Kao, L.S. Kanj, S.S. Kaplan, L.J. Kapoor, G. Karamarkovic, A. Kashuk, J. Kenig, J. Khamis, F. Khokha, V. Kiguba, R. Kirkpatrick, A.W. Kørner, H. Koike, K. Kok, K.Y.Y. Kon, K. Kong, V. Inaba, K. Ioannidis, O. Isik, A. Iskandar, K. Labbate, M. Labricciosa, F.M. Lagrou, K. Lagunes, L. Latifi, R. Lasithiotakis, K. Laxminarayan, R. Lee, J.G. Leone, M. Leppäniemi, A. Li, Y. Liang, S.Y. Liau, K.-H. Litvin, A. Loho, T. Lowman, W. Machain, G.M. Maier, R.V. Manzano-Nunez, R. Marinis, A. Marmorale, C. Martin-Loeches, I. Marwah, S. Maseda, E. McFarlane, M. De Melo, R.B. Melotti, M.R. Memish, Z. Mertz, D. Mesina, C. Menichetti, F. Mishra, S.K. Montori, G. Moore, E.E. Moore, F.A. Naidoo, N. Napolitano, L. Negoi, I. Nicolau, D.P. Nikolopoulos, I. Nord, C.E. Ofori-Asenso, R. Olaoye, I. Omari, A.H. Ordoñez, C.A. Ouadii, M. Ouedraogo, A.-S. Pagani, L. Paiva, J.A. Parreira, J.G. Pata, F. Pereira, J. Pereira, N.R. Petrosillo, N. Picetti, E. Pintar, T. Ponce-De-Leon, A. Popovski, Z. Poulakou, G. Preller, J. Guerrero, A.P. Pupelis, G. Quiodettis, M. Rawson, T.M. Reichert, M. Reinhart, K. Rems, M. Rello, J. Rizoli, S. Roberts, J. Rubio-Perez, I. Ruppé, E. Sakakushev, B. Sall, I. Kafil, H.S. Sanders, J. Sato, N. Sawyer, R.G. Scalea, T. Scibé, R. Scudeller, L. Lohse, H.S. Sganga, G. Shafiq, N. Shah, J.N. Spigaglia, P. Suroowan, S. Tsioutis, C. Sifri, C.D. Siribumrungwong, B. Sugrue, M. Talving, P. Tan, B.K. Tarasconi, A. Tascini, C. Tilsed, J. Timsit, J.-F. Tumbarello, M. Trung, N.T. Ulrych, J. Uranues, S. Velmahos, G. Vereczkei, A.G. Viale, P. Estape, J.V. Viscoli, C. Wagenlehner, F. Wright, B.J. Xiao, Y. Yuan, K.-C. Zachariah, S.K. Zahar, J.R. Mergulhão, P. Catena, F.
Abstract: This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections. As such, it is our intent to raise awareness among healthcare workers and improve antimicrobial prescribing. To facilitate its dissemination, the declaration was translated in different languages. © Copyright 2017, Mary Ann Liebert, Inc.
Published: 2017

44. Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

Author: Sartelli, M. Weber, D.G. Ruppé, E. Bassetti, M. Wright, B.J. Ansaloni, L. Catena, F. Coccolini, F. Abu-Zidan, F.M. Coimbra, R. Moore, E.E. Moore, F.A. Maier, R.V. De Waele, J.J. Kirkpatrick, A.W. Griffiths, E.A. Eckmann, C. Brink, A.J. Mazuski, J.E. May, A.K. Sawyer, R.G. Mertz, D. Montravers, P. Kumar, A. Roberts, J.A. Vincent, J.L. Watkins, R.R. Lowman, W. Spellberg, B. Abbott, I.J. Adesunkanmi, A.K. Al-Dahir, S. Al-Hasan, M.N. Agresta, F. Althani, A.A. Ansari, S. Ansumana, R. Augustin, G. Bala, M. Balogh, Z.J. Baraket, O. Bhangu, A. Beltrán, M.A. Bernhard, M. Biffl, W.L. Boermeester, M.A. Brecher, S.M. Cherry-Bukowiec, J.R. Buyne, O.R. Cainzos, M.A. Cairns, K.A. Camacho-Ortiz, A. Chandy, S.J. Che Jusoh, A. Chichom-Mefire, A. Colijn, C. Corcione, F. Cui, Y. Curcio, D. Delibegovic, S. Demetrashvili, Z. De Simone, B. Dhingra, S. Diaz, J.J. Di Carlo, I. Dillip, A. Di Saverio, S. Doyle, M.P. Dorj, G. Dogjani, A. Dupont, H. Eachempati, S.R. Enani, M.A. Egiev, V.N. Elmangory, M.M. Ferrada, P. Fitchett, J.R. Fraga, G.P. Guessennd, N. Giamarellou, H. Ghnnam, W. Gkiokas, G. Goldberg, S.R. Gomes, C.A. Gomi, H. Guzmán-Blanco, M. Haque, M. Hansen, S. Hecker, A. Heizmann, W.R. Herzog, T. Hodonou, A.M. Hong, S.K. Kafka-Ritsch, R. Kaplan, L.J. Kapoor, G. Karamarkovic, A. Kees, M.G. Kenig, J. Kiguba, R. Kim, P.K. Kluger, Y. Khokha, V. Koike, K. Kok, K.Y. Kong, V. Knox, M.C. Inaba, K. Isik, A. Iskandar, K. Ivatury, R.R. Labbate, M. Labricciosa, F.M. Laterre, P.F. Latifi, R. Lee, J.G. Lee, Y.R. Leone, M. Leppaniemi, A. Li, Y. Liang, S.Y. Loho, T. Maegele, M. Malama, S. Marei, H.E. Martin-Loeches, I. Marwah, S. Massele, A. McFarlane, M. Melo, R.B. Negoi, I. Nicolau, D.P. Nord, C.E. Ofori-Asenso, R. Omari, A.H. Ordonez, C.A. Ouadii, M. Pereira Júnior, G.A. Piazza, D. Pupelis, G. Rawson, T.M. Rems, M. Rizoli, S. Rocha, C. Sakakushev, B. Sanchez-Garcia, M. Sato, N. Segovia Lohse, H.A. Sganga, G. Siribumrungwong, B. Shelat, V.G. Soreide, K. Soto, R. Talving, P. Tilsed, J.V. Timsit, J.F. Trueba, G. Trung, N.T. Ulrych, J. van Goor, H. Vereczkei, A. Vohra, R.S. Wani, I. Uhl, W. Xiao, Y. Yuan, K.C. Zachariah, S.K. Zahar, J.R. Zakrison, T.L. Corcione, A. Melotti, R.M. Viscoli, C. Viale, P.
Subjects: lipids (amino acids, peptides, and proteins)
Abstract: The original article [1] contains an error whereby a co-author, Boris Sakakushev has their family name spelt incorrectly as 'Sakakhushev'. The authors would therefore like it known that the correct spelling of the family name is 'Sakakushev'. © The Author(s).
Published: 2017

45. Crystalloid resuscitation in trauma patients: deleterious effect of 5L or more in the first 24h

Author: Jones, D.G., primary, Nantais, J., additional, Rezende-Neto, J. B., additional, Yazdani, S., additional, Vegas, P., additional, and Rizoli, S., additional
Published: 2018
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46. Using rotational thromboelastometry clot firmness at 5 minutes (ROTEM®EXTEM A5) to predict massive transfusion and in-hospital mortality in trauma: a retrospective analysis of 1146 patients

Author: Kelly, J. M., primary, Rizoli, S., additional, Veigas, P., additional, Hollands, S., additional, and Min, A., additional
Published: 2018
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47. Erratum to: Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Sartelli, M., primary, Weber, D. G., additional, Ruppé, E., additional, Bassetti, M., additional, Wright, B. J., additional, Ansaloni, L., additional, Catena, F., additional, Coccolini, F., additional, Abu-Zidan, F. M., additional, Coimbra, R., additional, Moore, E. E., additional, Moore, F. A., additional, Maier, R. V., additional, De Waele, J. J., additional, Kirkpatrick, A. W., additional, Griffiths, E. A., additional, Eckmann, C., additional, Brink, A. J., additional, Mazuski, J. E., additional, May, A. K., additional, Sawyer, R. G., additional, Mertz, D., additional, Montravers, P., additional, Kumar, A., additional, Roberts, J. A., additional, Vincent, J. L., additional, Watkins, R. R., additional, Lowman, W., additional, Spellberg, B., additional, Abbott, I. J., additional, Adesunkanmi, A. K., additional, Al-Dahir, S., additional, Al-Hasan, M. N., additional, Agresta, F., additional, Althani, A. A., additional, Ansari, S., additional, Ansumana, R., additional, Augustin, G., additional, Bala, M., additional, Balogh, Z. J., additional, Baraket, O., additional, Bhangu, A., additional, Beltrán, M. A., additional, Bernhard, M., additional, Biffl, W. L., additional, Boermeester, M. A., additional, Brecher, S. M., additional, Cherry-Bukowiec, J. R., additional, Buyne, O. R., additional, Cainzos, M. A., additional, Cairns, K. A, additional, Camacho-Ortiz, A., additional, Chandy, S. J., additional, Che Jusoh, A., additional, Chichom-Mefire, A., additional, Colijn, C., additional, Corcione, F., additional, Cui, Y., additional, Curcio, D., additional, Delibegovic, S., additional, Demetrashvili, Z., additional, De Simone, B., additional, Dhingra, S., additional, Diaz, J. J., additional, Di Carlo, I., additional, Dillip, A., additional, Di Saverio, S., additional, Doyle, M. P., additional, Dorj, G., additional, Dogjani, A., additional, Dupont, H., additional, Eachempati, S. R., additional, Enani, M. A., additional, Egiev, V. N., additional, Elmangory, M. M., additional, Ferrada, P., additional, Fitchett, J. R., additional, Fraga, G. P., additional, Guessennd, N., additional, Giamarellou, H., additional, Ghnnam, W., additional, Gkiokas, G., additional, Goldberg, S. R., additional, Gomes, C. A., additional, Gomi, H., additional, Guzmán-Blanco, M., additional, Haque, M., additional, Hansen, S., additional, Hecker, A., additional, Heizmann, W. R., additional, Herzog, T., additional, Hodonou, A. M., additional, Hong, S. K., additional, Kafka-Ritsch, R., additional, Kaplan, L. J., additional, Kapoor, G., additional, Karamarkovic, A., additional, Kees, M. G., additional, Kenig, J., additional, Kiguba, R., additional, Kim, P. K., additional, Kluger, Y., additional, Khokha, V., additional, Koike, K., additional, Kok, K. Y., additional, Kong, V., additional, Knox, M. C., additional, Inaba, K., additional, Isik, A., additional, Iskandar, K., additional, Ivatury, R. R., additional, Labbate, M., additional, Labricciosa, F. M., additional, Laterre, P. F., additional, Latifi, R., additional, Lee, J. G., additional, Lee, Y. R., additional, Leone, M., additional, Leppaniemi, A., additional, Li, Y., additional, Liang, S. Y., additional, Loho, T., additional, Maegele, M., additional, Malama, S., additional, Marei, H. E., additional, Martin-Loeches, I., additional, Marwah, S., additional, Massele, A., additional, McFarlane, M., additional, Melo, R. B., additional, Negoi, I., additional, Nicolau, D. P., additional, Nord, C. E., additional, Ofori-Asenso, R., additional, Omari, A. H., additional, Ordonez, C. A., additional, Ouadii, M., additional, Pereira Júnior, G. A., additional, Piazza, D., additional, Pupelis, G., additional, Rawson, T. M., additional, Rems, M., additional, Rizoli, S., additional, Rocha, C., additional, Sakakushev, B., additional, Sanchez-Garcia, M., additional, Sato, N., additional, Segovia Lohse, H. A., additional, Sganga, G., additional, Siribumrungwong, B., additional, Shelat, V. G., additional, Soreide, K., additional, Soto, R., additional, Talving, P., additional, Tilsed, J. V., additional, Timsit, J. F., additional, Trueba, G., additional, Trung, N. T., additional, Ulrych, J., additional, van Goor, H., additional, Vereczkei, A., additional, Vohra, R. S., additional, Wani, I., additional, Uhl, W., additional, Xiao, Y., additional, Yuan, K. C., additional, Zachariah, S. K., additional, Zahar, J. R., additional, Zakrison, T. L., additional, Corcione, A., additional, Melotti, R. M., additional, Viscoli, C., additional, and Viale, P., additional
Published: 2017
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48. P103: A human factors-based framework analysis for patient safety: the trauma resuscitation using in situ simulation team training (TRUST) experience

Author: Petrosoniak, A., primary, Fan, M., additional, Trbovich, P., additional, White, K., additional, Pinkney, S., additional, McGowan, M., additional, Gray, A., additional, Campbell, D., additional, Rizoli, S., additional, and Hicks, C., additional
Published: 2017
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49. WSES classification and guidelines for liver trauma

Author: Coccolini, F, Catena, F, Moore, E, Ivatury, R, Biffl, W, Peitzman, A, Coimbra, R, Rizoli, S, Kluger, Y, Abu-Zidan, F, Ceresoli, M, Montori, G, Sartelli, M, Weber, D, Fraga, G, Naidoo, N, Moore, F, Zanini, N, Ansaloni, L, Coccolini, Federico, Catena, Fausto, Moore, Ernest E, Ivatury, Rao, Biffl, Walter, Peitzman, Andrew, Coimbra, Raul, Rizoli, Sandro, Kluger, Yoram, Abu-Zidan, Fikri M, Ceresoli, Marco, Montori, Giulia, Sartelli, Massimo, Weber, Dieter, Fraga, Gustavo, Naidoo, Noel, Moore, Frederick A, Zanini, Nicola, Ansaloni, Luca, Coccolini, F, Catena, F, Moore, E, Ivatury, R, Biffl, W, Peitzman, A, Coimbra, R, Rizoli, S, Kluger, Y, Abu-Zidan, F, Ceresoli, M, Montori, G, Sartelli, M, Weber, D, Fraga, G, Naidoo, N, Moore, F, Zanini, N, Ansaloni, L, Coccolini, Federico, Catena, Fausto, Moore, Ernest E, Ivatury, Rao, Biffl, Walter, Peitzman, Andrew, Coimbra, Raul, Rizoli, Sandro, Kluger, Yoram, Abu-Zidan, Fikri M, Ceresoli, Marco, Montori, Giulia, Sartelli, Massimo, Weber, Dieter, Fraga, Gustavo, Naidoo, Noel, Moore, Frederick A, Zanini, Nicola, and Ansaloni, Luca
Abstract: The severity of liver injuries has been universally classified according to the American Association for the Surgery of Trauma (AAST) grading scale. In determining the optimal treatment strategy, however, the haemodynamic status and associated injuries should be considered. Thus the management of liver trauma is ultimately based on the anatomy of the injury and the physiology of the patient. This paper presents the World Society of Emergency Surgery (WSES) classification of liver trauma and the management Guidelines.
Published: 2016

50. P095: Who, what, where: a critical assessment of helicopter emergency medical services transport and transfer times on patient outcomes at two level 1 trauma centres

Author: Nolan, B., primary, Ackery, A., additional, Tien, H., additional, Sawadsky, B., additional, Rizoli, S., additional, Mcfarlan, A., additional, and Phillips, A., additional
Published: 2016
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