Search

Your search keyword '"Ritter,Rene"' showing total 5 results
Start Over Author "Ritter,Rene"
5 results on '"Ritter,Rene"'

2. RF Performance of a Next-Generation L-Band RF Gun at PITZ

Author

Li,Xiangkun, Bousonville,Michael, Schlarb,Holger, Aftab,Namra, Boonpornprasert,Prach, Knebel,Lennart, Lueangaramwong,Anusorn, Schreiber,Siegfried, Jachmann,Lutz, Niemczyk,Raffael, Oppelt,Anne, Schultze,Joerg, Philipp,Sebastian, Melkumyan,David, Stephan,Frank, Hoffmann,Andreas, Castro-Carballo,Maria-Elena, Weilbach,Tobias, Lederer,Sven, Vashchenko,Grygorii, Adhikari,Gowri, Richard,Christopher, Pfeiffer,Sven, Pohl,Mario, Shu,Guan, Wenskat,Marc, Ritter,Rene, Good,James, Aboulbanine,Zakaria, Kostin,Denis, Krasilnikov,Mikhail, Hoffmann,Matthias, Lilje,Lutz, Brinker,Frank, Qian,Houjun, Koschitzki,Christian, Weise,Hans, Georgiev,Georgi, Ziegler,Joerg, Koehler,Winfried, Petrosyan,Bagrat, and Gross,Matthias

Subjects
electron-sources - Electron sources, Accelerator Physics
Abstract

A new generation of high-gradient normal conducting 1.3 GHz RF gun with 1% duty factor was developed to provide a high-quality electron source for superconducting linac driven free-electron lasers like FLASH and European XFEL. Compared to the Gun4 series, Gun5 aims for a ~50% longer RF pulse length (RF pulse duration of up to 1 ms at 10 Hz repetition rate) combined with high gradients (up to ~60 MV/m at the cathode). In addition to the improved cell geometry and cooling concept, the new cavity is equipped with an RF probe to measure and control the amplitude and phase of the RF field inside the gun. The first characterization of Gun5.1 included measurements of RF amplitude and phase stability (pulse-to-pulse and along 1 ms RF pulse). The dark current was measured at various peak power levels. The results of this characterization will be reported.

Published
2023
Full Text
View/download PDF

4. Nomograms including the UBC (R) Rapid test to detect primary bladder cancer based on a multicentre dataset

Author

Meisl, Christina J., Karakiewicz, Pierre, I, Einarsson, Roland, Koch, Stefan, Hallmann, Steffen, Weiss, Sarah, Hemdan, Tammer, Malmström, Per-Uno, Styrke, Johan, Sherif, Amir, Hasan, Mudhar N., Pichler, Renate, Tulchiner, Gennadi, Palou, Joan, Faba, Oscar Rodriguez, Hennenlotter, Joerg, Stenzl, Arnulf, Ritter, Rene, Niegisch, Guenter, Grunewald, Camilla M., Schlomm, Thorsten, Friedersdorff, Frank, Barski, Dimitri, Otto, Thomas, Goessl, Andreas, Arndt, Christian, Esuvaranathan, Kesavan, Kesavan, Nisha R., Zhijiang, Zang, Kramer, Mario W., Hennig, Martin J. P., Ecke, Thorsten H., Meisl, Christina J., Karakiewicz, Pierre, I, Einarsson, Roland, Koch, Stefan, Hallmann, Steffen, Weiss, Sarah, Hemdan, Tammer, Malmström, Per-Uno, Styrke, Johan, Sherif, Amir, Hasan, Mudhar N., Pichler, Renate, Tulchiner, Gennadi, Palou, Joan, Faba, Oscar Rodriguez, Hennenlotter, Joerg, Stenzl, Arnulf, Ritter, Rene, Niegisch, Guenter, Grunewald, Camilla M., Schlomm, Thorsten, Friedersdorff, Frank, Barski, Dimitri, Otto, Thomas, Goessl, Andreas, Arndt, Christian, Esuvaranathan, Kesavan, Kesavan, Nisha R., Zhijiang, Zang, Kramer, Mario W., Hennig, Martin J. P., and Ecke, Thorsten H.

Abstract

Objectives To evaluate the clinical utility of the urinary bladder cancer antigen test UBC (R) Rapid for the diagnosis of bladder cancer (BC) and to develop and validate nomograms to identify patients at high risk of primary BC. Patients and Methods Data from 1787 patients from 13 participating centres, who were tested between 2012 and 2020, including 763 patients with BC, were analysed. Urine samples were analysed with the UBC (R) Rapid test. The nomograms were developed using data from 320 patients and externally validated using data from 274 patients. The diagnostic accuracy of the UBC (R) Rapid test was evaluated using receiver-operating characteristic curve analysis. Brier scores and calibration curves were chosen for the validation. Biopsy-proven BC was predicted using multivariate logistic regression. Results The sensitivity, specificity, and area under the curve for the UBC (R) Rapid test were 46.4%, 75.5% and 0.61 (95% confidence interval [CI] 0.58-0.64) for low-grade (LG) BC, and 70.5%, 75.5% and 0.73 (95% CI 0.70-0.76) for high-grade (HG) BC, respectively. Age, UBC (R) Rapid test results, smoking status and haematuria were identified as independent predictors of primary BC. After external validation, nomograms based on these predictors resulted in areas under the curve of 0.79 (95% CI 0.72-0.87) and 0.95 (95% CI: 0.92-0.98) for predicting LG-BC and HG-BC, respectively, showing excellent calibration associated with a higher net benefit than the UBC (R) Rapid test alone for low and medium risk levels in decision curve analysis. The R Shiny app allows the results to be explored interactively and can be accessed at www.blucab-index. net. Conclusion The UBC (R) Rapid test alone has limited clinical utility for predicting the presence of BC. However, its combined use with BC risk factors including age, smoking status and haematuria provides a fast, highly accurate and non-invasive tool for screening patients for primary LG-BC and especially primary HG-BC.

Published
2022
Full Text
View/download PDF

5. RF Performance of a Next-Generation L-Band RF Gun at PITZ

Author

Krasilnikov, Mikhail, Aboulbanine, Zakaria, Adhikari, Gowri, Aftab, Namra, Boonpornprasert, Prach, Bousonville, Michael, Brinker, Frank, Castro Carballo, Maria Elena, Georgiev, Georgi, Good, James, Groß, Matthias, Hoffmann, Andreas, Hoffmann, Matthias, Knebel, Lennart, Koschitzki, Christian, Kostin, Denis, Lederer, Sven, Li, Xiangkun, Lilje, Lutz, Lueangaramwong, Anusorn, Melkumyan, David, Niemczyk, Raffael, Oppelt, Anne, Petrosyan, Bagrat, Pfeiffer, Sven, Philipp, Sebastian, Pohl, Mario, Qian, Houjun, Richard, Christopher, Ritter, Rene, Schreiber, Siegfried, Schultze, Joerg, Shu, Guan, Stephan, Frank, Vashchenko, Grygorii, Weilbach, Tobias, Weise, Hans, Wenskat, Marc, and Ziegler, Joerg

Subjects
electron, FEL, linear accelerator, superconductivity, vacuum, free electron laser, cavity, Accelerator Physics, monitoring, gun, DESY FLASH, electron, particle source, impedance, Electron Accelerators and Applications, performance
Abstract

Proceedings of the 31st International Linear Accelerator Conference, LINAC2022, Liverpool, UK 31st Linear Accelerator Conference, LINAC22, Liverpool, United Kingdom, 28 Aug 2022 - 2 Sep 2022; JACoW Publishing, Geneva, Switzerland 699-702 (2022). doi:10.18429/JACoW-LINAC2022-THPOJO03, A new generation of normal conducting 1.3GHz RF gun was developed to provide a high-quality electron source for superconducting linac driven free-electron lasers like FLASH and European XFEL. Compared to the Gun4 series, Gun5 aims for a 50% increase of the duration of the RF pulse (up to 1 ms at 10 Hz repetition rate) combined with high gradients (up to ~60 MV/m at the cathode). In addition to the improved impedance, the new cavity is equipped with an RF probe to measure and control the amplitude and phase of the RF field inside the gun. The first prototype of the new RF gun was manufactured at DESY and installed at the Photo Injector Test facility at DESY in Zeuthen (PITZ) in October 2021. In mid-October 2021 the RF conditioning began, aiming for achieving the aforementioned RF parameters. The conditioning procedure involves a slow gradual increase in repetition rate, RF pulse duration and peak power while carefully monitoring vacuum conditions and signals from interlock sensors. The results of RF conditioning will be reported., Published by JACoW Publishing, Geneva, Switzerland

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results