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1. Prevalence and Characteristics of Sleep Apnea in Intensive Care Unit Survivors After SARS-CoV-2 Pneumonia

Author: Traore I, Eberst G, Claudé F, Laurent L, Meurisse A, Paget-Bailly S, Roux-Claudé P, Jacoulet P, Barnig C, Martarello R, Poirson B, Bouiller K, Chirouze C, Behr J, Grillet F, Ritter O, Pili-Floury S, Winiszewski H, Samain E, Capellier G, and Westeel V
Subjects: sars-cov-2. pneumonia. obstructive sleep apnea syndrome. intensive care unit., Psychiatry, RC435-571, Neurophysiology and neuropsychology, QP351-495
Abstract: Ibrahim Traore,1 Guillaume Eberst,1– 3 Fréderic Claudé,1 Lucie Laurent,1 Aurelia Meurisse,2,3 Sophie Paget-Bailly,2,3 Pauline Roux-Claudé,1 Pascale Jacoulet,1 Cindy Barnig,1 Rachel Martarello,1 Bastien Poirson,4 Kevin Bouiller,5 Catherine Chirouze,5 Julien Behr,6 Franck Grillet,6 Ophélie Ritter,1 Sébastien Pili-Floury,7 Hadrien Winiszewski,8 Emmanuel Samain,7,9 Gilles Capellier,8– 10 Virginie Westeel1– 3 1Respiratory Medicine Department, University Hospital of Besançon, Besançon, France; 2Methodology and Quality of Life in Oncology Unit, University Hospital, Besançon, France; 3UMR 1098, University of Franche-Comté, Besançon, France; 4Department of Geriatrics, University Hospital of Besançon, Besançon, France; 5Department of Infectious Disease, University Hospital of Besançon, Besançon, France; 6Department of Radiology, University Hospital of Besançon, Besançon, France; 7Anesthesia and Intensive Care Unit, University Hospital of Besançon, Besançon, France; 8Medical Intensive Care Unit, University Hospital of Besançon, Besançon, France; 9Research Unit EA3920, Université de Franche Comté, Besançon, France; 10Australian and New Zealand Intensive Care Research Center, Department of Epidemiology and Preventive Medicine, Monash University, Monash, AustraliaCorrespondence: Ibrahim Traore, Respiratory Medicine Department, University Hospital of Besançon, Besançon, France, Email traore.ibrahim180@gmail.comBackground: Sleep apnea (SA) was reported as possibly exacerbating symptoms of COVID-19, a disease induced by SARS-CoV-2 virus. The same comorbidities are common with both pathologies. This study aimed to estimate the prevalence, characteristics of SA and variation in AHI three months after severe COVID-19 requiring intensive care unit (ICU) admission.Methods: A prospective cohort of patients admitted to ICU for severe COVID-19 underwent an overnight home polygraphy 3 months after onset of symptoms, as part of a comprehensive follow-up program (pulmonary function tests, 6-minute walk tests and chest CT-scan). Patients with an apnea hypopnea index (AHI) ≥ 5 were considered as having SA. We performed a comparative descriptive analysis of 2 subgroups according to the existence, severity of SA and indication for effective SA treatment: patients with absent or mild SA (AHI < 15) vs patients with moderate to severe SA (AHI ≥ 15).Results: Among 68 patients included, 62 (91%) had known comorbidities (34 hypertension, 21 obesity, 20 dyslipidemia, 16 type 2 diabetes). It has been observed a preexisting SA for 13 patients (19.1%). At 3 months, 62 patients (91%) had SA with 85.5% of obstructive events. Twenty-four patients had no or a mild SA (AHI < 15) and 44 had moderate to severe SA (AHI ≥ 15). Ischemic heart disease exclusively affected the moderate to severe SA group. Except for thoracic CT-scan which revealed less honeycomb lesions, COVID-19 symptoms were more severe in the group with moderate to severe SA, requiring a longer curarization, more prone position sessions and more frequent tracheotomy.Conclusion: SA involved 91% of patients in our population at 3 months of severe COVID-19 and was mainly obstructive type. Although SA might be a risk factor as well as consequences of ICU care in severe COVID-19 infection, our results underline the importance of sleep explorations after an ICU stay for this disease.Keywords: SARS-CoV-2, pneumonia, obstructive sleep apnea syndrome, intensive care unit
Published: 2022

2. The impact of aerobic and isometric exercise on different measures of dysfunctional high-density lipoprotein in patients with hypertension

Author: Pagonas, Nikolaos, Vlatsas, Stergios, Bauer, Frederic, Seibert, Felix S, Sasko, B, Buschmann, I, Ritter, O, Kelesidis, Theodoros, and Westhoff, Timm H
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Cardiovascular, Atherosclerosis, Clinical Research, Clinical Trials and Supportive Activities, Prevention, Hypertension, 6.7 Physical, Evaluation of treatments and therapeutic interventions, Adult, Aged, Biomarkers, Blood Pressure, Cholesterol, HDL, Exercise, Female, Germany, Humans, Isometric Contraction, Lipoproteins, HDL, Male, Middle Aged, Oxidation-Reduction, Prospective Studies, Time Factors, Treatment Outcome, Aerobic exercise, isometric exercise, HDL function, lipids, hypertension, Cardiovascular medicine and haematology
Abstract: BackgroundExercise training increases high-density lipoprotein (HDL) cholesterol, but its effect on HDL function is unclear. In hypertensives, exercise improves endothelial dysfunction, which is related to HDL function. In the present study, we assess for the first time the effects of different exercise modalities on two cell-free assays of HDL function.DesignThe study was conducted as a prospective randomized controlled trial in 75 hypertensive patients.MethodsPatients were randomized in three groups: (a) handgrip isometric training five times weekly; (b) placebo-handgrip; and (c) aerobic exercise training at least three times per week. HDL function was assessed in serum samples at baseline and after 12 weeks of training by two independent assays that determine the proinflammatory phenotype (haptoglobin content) of a specific amount of HDL (Haptoglobin-HDL [HPHDL]) and oxidized HDL (HDLox) as a measure of reduced antioxidant function of HDL. HDL function measures were normalized by the measures of a pooled control of sera from healthy participants and by HDL-C levels (normalized ratio, no units).ResultsAerobic exercise led to significant reduction of the HDLox from 0.99 ± 0.27 to 0.90 ± 0.29 (no units, p = 0.03). The HPHDL did not change in any training group. Changes of HDLox correlated with reduction of the systolic blood pressure only after aerobic exercise (R = 0.64, p = 0.03).ConclusionsAerobic but not isometric exercise improves the antioxidant function of HDL in patients with hypertension. This improvement correlates positively with reductions of blood pressure.
Published: 2019

3. Impact of diabetes on the management and outcomes in atrial fibrillation: an analysis from the ESC-EHRA EORP-AF Long-Term General Registry

Author: Boriani, G., Lip, G.Y.H., Tavazzi, L., Maggioni, A.P., Dan, G.-A., Potpara, T., Nabauer, M., Marin, F., Kalarus, Z., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., García Bolao, I., Piot, O., Etsadashvili, K., Simantirakis, E., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K.A., Erglis, A., Poposka, L., Burg, M., Crijns, H., Erküner, Ö., Atar, D., Lenarczyk, R., Martins Oliveira, M., Shah, D., Serdechnaya, E., Diker, E., Lane, D., Zëra, E., Ekmekçiu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., el Husseini, Z., Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., Van Genechten, G., Heidbuchel, H., Boussy, T., De Coninck, M., Van Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., Van Hauwaert, B., Kuppens, C., Faes, D., Van Lier, D., Van Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska-Georgieva, S., Slavcheva, S., Yotov, Y., Kubíčková, M., Marni Joensen, A., Gammelmark, A., Hvilsted Rasmussen, L., Dinesen, P., Krogh Venø, S., Sorensen, B., Korsgaard, A., Andersen, K., Fragtrup Hellum, C., Svenningsen, A., Nyvad, O., Wiggers, P., May, O., Aarup, A., Graversen, B., Jensen, L., Andersen, M., Svejgaard, M., Vester, S., Hansen, S., Lynggaard, V., Ciudad, M., Vettus, R., Maestre, A., Castaño, S., Cheggour, S., Poulard, J., Mouquet, V., Leparrée, S., Bouet, J., Taieb, J., Doucy, A., Duquenne, H., Furber, A., Dupuis, J., Rautureau, J., Font, M., Damiano, P., Lacrimini, M., Abalea, J., Boismal, S., Menez, T., Mansourati, J., Range, G., Gorka, H., Laure, C., Vassalière, C., Elbaz, N., Lellouche, N., Djouadi, K., Roubille, F., Dietz, D., Davy, J., Granier, M., Winum, P., Leperchois-Jacquey, C., Kassim, H., Marijon, E., Le Heuzey, J., Fedida, J., Maupain, C., Himbert, C., Gandjbakhch, E., Hidden-Lucet, F., Duthoit, G., Badenco, N., Chastre, T., Waintraub, X., Oudihat, M., Lacoste, J., Stephan, C., Bader, H., Delarche, N., Giry, L., Arnaud, D., Lopez, C., Boury, F., Brunello, I., Lefèvre, M., Mingam, R., Haissaguerre, M., Le Bidan, M., Pavin, D., Le Moal, V., Leclercq, C., Beitar, T., Martel, I., Schmid, A., Sadki, N., Romeyer-Bouchard, C., Da Costa, A., Arnault, I., Boyer, M., Piat, C., Lozance, N., Nastevska, S., Doneva, A., Fortomaroska Milevska, B., Sheshoski, B., Petroska, K., Taneska, N., Bakrecheski, N., Lazarovska, K., Jovevska, S., Ristovski, V., Antovski, A., Lazarova, E., Kotlar, I., Taleski, J., Kedev, S., Zlatanovik, N., Jordanova, S., Bajraktarova Proseva, T., Doncovska, S., Maisuradze, D., Esakia, A., Sagirashvili, E., Lartsuliani, K., Natelashvili, N., Gumberidze, N., Gvenetadze, R., Gotonelia, N., Kuridze, N., Papiashvili, G., Menabde, I., Glöggler, S., Napp, A., Lebherz, C., Romero, H., Schmitz, K., Berger, M., Zink, M., Köster, S., Sachse, J., Vonderhagen, E., Soiron, G., Mischke, K., Reith, R., Schneider, M., Rieker, W., Boscher, D., Taschareck, A., Beer, A., Oster, D., Ritter, O., Adamczewski, J., Walter, S., Frommhold, A., Luckner, E., Richter, J., Schellner, M., Landgraf, S., Bartholome, S., Naumann, R., Schoeler, J., Westermeier, D., William, F., Wilhelm, K., Maerkl, M., Oekinghaus, R., Denart, M., Kriete, M., Tebbe, U., Scheibner, T., Gruber, M., Gerlach, A., Beckendorf, C., Anneken, L., Arnold, M., Lengerer, S., Bal, Z., Uecker, C., Förtsch, H., Fechner, S., Mages, V., Martens, E., Methe, H., Schmidt, T., Schaeffer, B., Hoffmann, B., Moser, J., Heitmann, K., Willems, S., Klaus, C., Lange, I., Durak, M., Esen, E., Mibach, F., Mibach, H., Utech, A., Gabelmann, M., Stumm, R., Ländle, V., Gartner, C., Goerg, C., Kaul, N., Messer, S., Burkhardt, D., Sander, C., Orthen, R., Kaes, S., Baumer, A., Dodos, F., Barth, A., Schaeffer, G., Gaertner, J., Winkler, J., Fahrig, A., Aring, J., Wenzel, I., Steiner, S., Kliesch, A., Kratz, E., Winter, K., Schneider, P., Haag, A., Mutscher, I., Bosch, R., Taggeselle, J., Meixner, S., Schnabel, A., Shamalla, A., Hötz, H., Korinth, A., Rheinert, C., Mehltretter, G., Schön, B., Schön, N., Starflinger, A., Englmann, E., Baytok, G., Laschinger, T., Ritscher, G., Gerth, A., Dechering, D., Eckardt, L., Kuhlmann, M., Proskynitopoulos, N., Brunn, J., Foth, K., Axthelm, C., Hohensee, H., Eberhard, K., Turbanisch, S., Hassler, N., Koestler, A., Stenzel, G., Kschiwan, D., Schwefer, M., Neiner, S., Hettwer, S., Haeussler-Schuchardt, M., Degenhardt, R., Sennhenn, S., Brendel, M., Stoehr, A., Widjaja, W., Loehndorf, S., Logemann, A., Hoskamp, J., Grundt, J., Block, M., Ulrych, R., Reithmeier, A., Panagopoulos, V., Martignani, C., Bernucci, D., Fantecchi, E., Diemberger, I., Ziacchi, M., Biffi, M., Cimaglia, P., Frisoni, J., Giannini, I., Boni, S., Fumagalli, S., Pupo, S., Di Chiara, A., Mirone, P., Pesce, F., Zoccali, C., Malavasi, V.L., Mussagaliyeva, A., Ahyt, B., Salihova, Z., Koshum-Bayeva, K., Kerimkulova, A., Bairamukova, A., Lurina, B., Zuzans, R., Jegere, S., Mintale, I., Kupics, K., Jubele, K., Kalejs, O., Vanhear, K., Cachia, M., Abela, E., Warwicker, S., Tabone, T., Xuereb, R., Asanovic, D., Drakalovic, D., Vukmirovic, M., Pavlovic, N., Music, L., Bulatovic, N., Boskovic, A., Uiterwaal, H., Bijsterveld, N., De Groot, J., Neefs, J., van den Berg, N., Piersma, F., Wilde, A., Hagens, V., Van Es, J., Van Opstal, J., Van Rennes, B., Verheij, H., Breukers, W., Tjeerdsma, G., Nijmeijer, R., Wegink, D., Binnema, R., Said, S., Philippens, S., van Doorn, W., Szili-Torok, T., Bhagwandien, R., Janse, P., Muskens, A., van Eck, M., Gevers, R., van der Ven, N., Duygun, A., Rahel, B., Meeder, J., Vold, A., Holst Hansen, C., Engset, I., Dyduch-Fejklowicz, B., Koba, E., Cichocka, M., Sokal, A., Kubicius, A., Pruchniewicz, E., Kowalik-Sztylc, A., Czapla, W., Mróz, I., Kozlowski, M., Pawlowski, T., Tendera, M., Winiarska-Filipek, A., Fidyk, A., Slowikowski, A., Haberka, M., Lachor-Broda, M., Biedron, M., Gasior, Z., Kołodziej, M., Janion, M., Gorczyca-Michta, I., Wozakowska-Kaplon, B., Stasiak, M., Jakubowski, P., Ciurus, T., Drozdz, J., Simiera, M., Zajac, P., Wcislo, T., Zycinski, P., Kasprzak, J., Olejnik, A., Harc-Dyl, E., Miarka, J., Pasieka, M., Ziemińska-Łuć, M., Bujak, W., Śliwiński, A., Grech, A., Morka, J., Petrykowska, K., Prasał, M., Hordyński, G., Feusette, P., Lipski, P., Wester, A., Streb, W., Romanek, J., Woźniak, P., Chlebuś, M., Szafarz, P., Stanik, W., Zakrzewski, M., Kaźmierczak, J., Przybylska, A., Skorek, E., Błaszczyk, H., Stępień, M., Szabowski, S., Krysiak, W., Szymańska, M., Karasiński, J., Blicharz, J., Skura, M., Hałas, K., Michalczyk, L., Orski, Z., Krzyżanowski, K., Skrobowski, A., Zieliński, L., Tomaszewska-Kiecana, M., Dłużniewski, M., Kiliszek, M., Peller, M., Budnik, M., Balsam, P., Opolski, G., Tymińska, A., Ozierański, K., Wancerz, A., Borowiec, A., Majos, E., Dabrowski, R., Szwed, H., Musialik-Lydka, A., Leopold-Jadczyk, A., Jedrzejczyk-Patej, E., Koziel, M., Mazurek, M., Krzemien-Wolska, K., Starosta, P., Nowalany-Kozielska, E., Orzechowska, A., Szpot, M., Staszel, M., Almeida, S., Pereira, H., Brandão Alves, L., Miranda, R., Ribeiro, L., Costa, F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragão, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhães, P., Fontes, P., Leão, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Dan, G., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu-Andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Ioachim Popescu, M., Nistor, D., Sus, I., Coborosanu, O., Alina-Ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Vukmirovic, L., Radisavljevic, M., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Radovanovic, S., Kocijancic, A., Obrenovic-Kircanski, B., Kalimanovska Ostric, D., Simic, D., Jovanovic, I., Petrovic, I., Polovina, M., Vukicevic, M., Tomasevic, M., Mujovic, N., Radivojevic, N., Petrovic, O., Aleksandric, S., Kovacevic, V., Mijatovic, Z., Ivanovic, B., Tesic, M., Ristic, A., Vujisic-Tesic, B., Nedeljkovic, M., Karadzic, A., Uscumlic, A., Prodanovic, M., Zlatar, M., Asanin, M., Bisenic, B., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Backovic, S., Stevanovic, A., Andric, A., Pencic, B., Pavlovic-Kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric-Cupic, V., Djordjevic, D., Damjanovic, M., Zdravkovic, S., Topic, V., Stanojevic, D., Randjelovic, M., Jankovic-Tomasevic, R., Atanaskovic, V., Antic, S., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Markovic, S., Mijatovic, A., Tanasic, D., Radakovic, G., Peranovic, J., Panic-Jelic, N., Vujadinovic, O., Pajic, P., Bekic, S., Kovacevic, S., García Fernandez, A., Perez Cabeza, A., Anguita, M., Tercedor Sanchez, L., Mau, E., Loayssa, J., Ayarra, M., Carpintero, M., Roldán Rabadan, I., Gil Ortega, M., Tello Montoliu, A., Orenes Piñero, E., Manzano Fernández, S., Marín, F., Romero Aniorte, A., Veliz Martínez, A., Quintana Giner, M., Ballesteros, G., Palacio, M., Alcalde, O., García-Bolao, I., Bertomeu Gonzalez, V., Otero-Raviña, F., García Seara, J., Gonzalez Juanatey, J., Dayal, N., Maziarski, P., Gentil-Baron, P., Koç, M., Onrat, E., Dural, I.E., Yilmaz, K., Özin, B., Tan Kurklu, S., Atmaca, Y., Canpolat, U., Tokgozoglu, L., Dolu, A.K., Demirtas, B., Sahin, D., Ozcan Celebi, O., Gagirci, G., Turk, U.O., Ari, H., Polat, N., Toprak, N., Sucu, M., Akin Serdar, O., Taha Alper, A., Kepez, A., Yuksel, Y., Uzunselvi, A., Yuksel, S., Sahin, M., Kayapinar, O., Ozcan, T., Kaya, H., Yilmaz, M.B., Kutlu, M., Demir, M., Gibbs, C., Kaminskiene, S., Bryce, M., Skinner, A., Belcher, G., Hunt, J., Stancombe, L., Holbrook, B., Peters, C., Tettersell, S., Shantsila, A., Senoo, K., Proietti, M., Russell, K., Domingos, P., Hussain, S., Partridge, J., Haynes, R., Bahadur, S., Brown, R., McMahon, S., McDonald, J., Balachandran, K., Singh, R., Garg, S., Desai, H., Davies, K., Goddard, W., Galasko, G., Rahman, I., Chua, Y., Payne, O., Preston, S., Brennan, O., Pedley, L., Whiteside, C., Dickinson, C., Brown, J., Jones, K., Benham, L., Brady, R., Buchanan, L., Ashton, A., Crowther, H., Fairlamb, H., Thornthwaite, S., Relph, C., McSkeane, A., Poultney, U., Kelsall, N., Rice, P., Wilson, T., Wrigley, M., Kaba, R., Patel, T., Young, E., Law, J., Runnett, C., Thomas, H., McKie, H., Fuller, J., Pick, S., Sharp, A., Hunt, A., Thorpe, K., Hardman, C., Cusack, E., Adams, L., Hough, M., Keenan, S., Bowring, A., Watts, J., Zaman, J., Goffin, K., Nutt, H., Beerachee, Y., Featherstone, J., Mills, C., Pearson, J., Stephenson, L., Grant, S., Wilson, A., Hawksworth, C., Alam, I., Robinson, M., Ryan, S., Egdell, R., Gibson, E., Holland, M., Leonard, D., Mishra, B., Ahmad, S., Randall, H., Hill, J., Reid, L., George, M., McKinley, S., Brockway, L., Milligan, W., Sobolewska, J., Muir, J., Tuckis, L., Winstanley, L., Jacob, P., Kaye, S., Morby, L., Jan, A., Sewell, T., Boos, C., Wadams, B., Cope, C., Jefferey, P., Andrews, N., Getty, A., Suttling, A., Turner, C., Hudson, K., Austin, R., Howe, S., Iqbal, R., Gandhi, N., Brophy, K., Mirza, P., Willard, E., Collins, S., Ndlovu, N., Subkovas, E., Karthikeyan, V., Waggett, L., Wood, A., Bolger, A., Stockport, J., Evans, L., Harman, E., Starling, J., Williams, L., Saul, V., Sinha, M., Bell, L., Tudgay, S., Kemp, S., Frost, L., Ingram, T., Loughlin, A., Adams, C., Adams, M., Hurford, F., Owen, C., Miller, C., Donaldson, D., Tivenan, H., Button, H., Nasser, A., Jhagra, O., Stidolph, B., Brown, C., Livingstone, C., Duffy, M., Madgwick, P., Roberts, P., Greenwood, E., Fletcher, L., Beveridge, M., Earles, S., McKenzie, D., Beacock, D., Dayer, M., Seddon, M., Greenwell, D., Luxton, F., Venn, F., Mills, H., Rewbury, J., James, K., Roberts, K., Tonks, L., Felmeden, D., Taggu, W., Summerhayes, A., Hughes, D., Sutton, J., Felmeden, L., Khan, M., Walker, E., Norris, L., O'Donohoe, L., Mozid, A., Dymond, H., Lloyd-Jones, H., Saunders, G., Simmons, D., Coles, D., Cotterill, D., Beech, S., Kidd, S., Wrigley, B., Petkar, S., Smallwood, A., Jones, R., Radford, E., Milgate, S., Metherell, S., Cottam, V., Buckley, C., Broadley, A., Wood, D., Allison, J., Rennie, K., Balian, L., Howard, L., Pippard, L., Board, S., Pitt-Kerby, T., Ding, Wern Yew, Kotalczyk, Agnieszka, Boriani, Giuseppe, Marin, Francisco, Blomström-Lundqvist, Carina, Potpara, Tatjana S., Fauchier, Laurent, and Lip, Gregory.Y.H.
Published: 2022
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4. Cardiac troponins and adverse outcomes in European patients with atrial fibrillation: A report from the ESC-EHRA EORP atrial fibrillation general long-term registry

Author: Boriani, G., Lip, G.Y.H., Tavazzi, L., Maggioni, A.P., Dan, G-A., Potpara, T., Nabauer, M., Marin, F., Kalarus, Z., Fauchier, L., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., García Bolao, I., Piot, O., Etsadashvili, K., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K., Erglis, A., Poposka, L., Burg, M.R., Crijns, H., Erküner, Ö., Atar, D., Lenarczyk, R., Martins Oliveira, M., Shah, D., Serdechnaya, E., Diker, E., Zëra, E., Ekmekçiu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., el Husseini, Z., Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., Van Genechten, G., Heidbuchel, H., Boussy, T., De Coninck, M., Van Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., Van Hauwaert, B., Kuppens, C., Faes, D., Van Lier, D., Van Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska-Georgieva, S., Slavcheva, S., Yotov, Y., Kubíčková, M., Marni Joensen, A., Gammelmark, A., Hvilsted Rasmussen, L., Dinesen, P., Krogh Venø, S., Sorensen, B., Korsgaard, A., Andersen, K., Fragtrup Hellum, C., Svenningsen, A., Nyvad, O., Wiggers, P., May, O., Aarup, A., Graversen, B., Jensen, L., Andersen, M., Svejgaard, M., Vester, S., Hansen, S., Lynggaard, V., Ciudad, M., Vettus, R., Maestre, A., Castaño, S., Cheggour, S., Poulard, J., Mouquet, V., Leparrée, S., Bouet, J., Taieb, J., Doucy, A., Duquenne, H., Furber, A., Dupuis, J., Rautureau, J., Font, M., Damiano, P., Lacrimini, M., Abalea, J., Boismal, S., Menez, T., Mansourati, J., Range, G., Gorka, H., Laure, C., Vassalière, C., Elbaz, N., Lellouche, N., Djouadi, K., Roubille, F., Dietz, D., Davy, J., Granier, M., Winum, P., Leperchois-Jacquey, C., Kassim, H., Marijon, E., Le Heuzey, J., Fedida, J., Maupain, C., Himbert, C., Gandjbakhch, E., Hidden-Lucet, F., Duthoit, G., Badenco, N., Chastre, T., Waintraub, X., Oudihat, M., Lacoste, J., Stephan, C., Bader, H., Delarche, N., Giry, L., Arnaud, D., Lopez, C., Boury, F., Brunello, I., Lefèvre, M., Mingam, R., Haissaguerre, M., Le Bidan, M., Pavin, D., Le Moal, V., Leclercq, C., Beitar, T., Martel, I., Schmid, A., Sadki, N., Romeyer-Bouchard, C., Da Costa, A., Arnault, I., Boyer, M., Piat, C., Lozance, N., Nastevska, S., Doneva, A., Fortomaroska Milevska, B., Sheshoski, B., Petroska, K., Taneska, N., Bakrecheski, N., Lazarovska, K., Jovevska, S., Ristovski, V., Antovski, A., Lazarova, E., Kotlar, I., Taleski, J., Kedev, S., Zlatanovik, N., Jordanova, S., Bajraktarova Proseva, T., Doncovska, S., Maisuradze, D., Esakia, A., Sagirashvili, E., Lartsuliani, K., Natelashvili, N., Gumberidze, N., Gvenetadze, R., Gotonelia, N., Kuridze, N., Papiashvili, G., Menabde, I., Glöggler, S., Napp, A., Lebherz, C., Romero, H., Schmitz, K., Berger, M., Zink, M., Köster, S., Sachse, J., Vonderhagen, E., Soiron, G., Mischke, K., Reith, R., Schneider, M., Rieker, W., Boscher, D., Taschareck, A., Beer, A., Oster, D., Ritter, O., Adamczewski, J., Walter, S., Frommhold, A., Luckner, E., Richter, J., Schellner, M., Landgraf, S., Bartholome, S., Naumann, R., Schoeler, J., Westermeier, D., William, F., Wilhelm, K., Maerkl, M., Oekinghaus, R., Denart, M., Kriete, M., Tebbe, U., Scheibner, T., Gruber, M., Gerlach, A., Beckendorf, C., Anneken, L., Arnold, M., Lengerer, S., Bal, Z., Uecker, C., Förtsch, H., Fechner, S., Mages, V., Martens, E., Methe, H., Schmidt, T., Schaeffer, B., Hoffmann, B., Moser, J., Heitmann, K., Willems, S., Klaus, C., Lange, I., Durak, M., Esen, E., Mibach, F., Mibach, H., Utech, A., Gabelmann, M., Stumm, R., Ländle, V., Gartner, C., Goerg, C., Kaul, N., Messer, S., Burkhardt, D., Sander, C., Orthen, R., Kaes, S., Baumer, A., Dodos, F., Barth, A., Schaeffer, G., Gaertner, J., Winkler, J., Fahrig, A., Aring, J., Wenzel, I., Steiner, S., Kliesch, A., Kratz, E., Winter, K., Schneider, P., Haag, A., Mutscher, I., Bosch, R., Taggeselle, J., Meixner, S., Schnabel, A., Shamalla, A., Hötz, H., Korinth, A., Rheinert, C., Mehltretter, G., Schön, B., Schön, N., Starflinger, A., Englmann, E., Baytok, G., Laschinger, T., Ritscher, G., Gerth, A., Dechering, D., Eckardt, L., Kuhlmann, M., Proskynitopoulos, N., Brunn, J., Foth, K., Axthelm, C., Hohensee, H., Eberhard, K., Turbanisch, S., Hassler, N., Koestler, A., Stenzel, G., Kschiwan, D., Schwefer, M., Neiner, S., Hettwer, S., Haeussler-Schuchardt, M., Degenhardt, R., Sennhenn, S., Brendel, M., Stoehr, A., Widjaja, W., Loehndorf, S., Logemann, A., Hoskamp, J., Grundt, J., Block, M., Ulrych, R., Reithmeier, A., Panagopoulos, V., Martignani, C., Bernucci, D., Fantecchi, E., Diemberger, I., Ziacchi, M., Biffi, M., Cimaglia, P., Frisoni, J., Giannini, I., Boni, S., Fumagalli, S., Pupo, S., Di Chiara, A., Mirone, P., Pesce, F., Zoccali, C., Malavasi, V.L., Mussagaliyeva, A., Ahyt, B., Salihova, Z., Koshum-Bayeva, K., Kerimkulova, A., Bairamukova, A., Lurina, B., Zuzans, R., Jegere, S., Mintale, I., Kupics, K., Jubele, K., Kalejs, O., Vanhear, K., Burg, M., Cachia, M., Abela, E., Warwicker, S., Tabone, T., Xuereb, R., Asanovic, D., Drakalovic, D., Vukmirovic, M., Pavlovic, N., Music, L., Bulatovic, N., Boskovic, A., Uiterwaal, H., Bijsterveld, N., De Groot, J., Neefs, J., van den Berg, N., Piersma, F., Wilde, A., Hagens, V., Van Es, J., Van Opstal, J., Van Rennes, B., Verheij, H., Breukers, W., Tjeerdsma, G., Nijmeijer, R., Wegink, D., Binnema, R., Said, S., Philippens, S., van Doorn, W., Szili-Torok, T., Bhagwandien, R., Janse, P., Muskens, A., van Eck, M., Gevers, R., van der Ven, N., Duygun, A., Rahel, B., Meeder, J., Vold, A., Holst Hansen, C., Engset, I., Dyduch-Fejklowicz, B., Koba, E., Cichocka, M., Sokal, A., Kubicius, A., Pruchniewicz, E., Kowalik-Sztylc, A., Czapla, W., Mróz, I., Kozlowski, M., Pawlowski, T., Tendera, M., Winiarska-Filipek, A., Fidyk, A., Slowikowski, A., Haberka, M., Lachor-Broda, M., Biedron, M., Gasior, Z., Kołodziej, M., Janion, M., Gorczyca-Michta, I., Wozakowska-Kaplon, B., Stasiak, M., Jakubowski, P., Ciurus, T., Drozdz, J., Simiera, M., Zajac, P., Wcislo, T., Zycinski, P., Kasprzak, J., Olejnik, A., Harc-Dyl, E., Miarka, J., Pasieka, M., Ziemińska-Łuć, M., Bujak, W., Śliwiński, A., Grech, A., Morka, J., Petrykowska, K., Prasał, M., Hordyński, G., Feusette, P., Lipski, P., Wester, A., Streb, W., Romanek, J., Woźniak, P., Chlebuś, M., Szafarz, P., Stanik, W., Zakrzewski, M., Kaźmierczak, J., Przybylska, A., Skorek, E., Błaszczyk, H., Stępień, M., Szabowski, S., Krysiak, W., Szymańska, M., Karasiński, J., Blicharz, J., Skura, M., Hałas, K., Michalczyk, L., Orski, Z., Krzyżanowski, K., Skrobowski, A., Zieliński, L., Tomaszewska-Kiecana, M., Dłużniewski, M., Kiliszek, M., Peller, M., Budnik, M., Balsam, P., Opolski, G., Tymińska, A., Ozierański, K., Wancerz, A., Borowiec, A., Majos, E., Dabrowski, R., Szwed, H., Musialik-Lydka, A., Leopold-Jadczyk, A., Jedrzejczyk-Patej, E., Koziel, M., Mazurek, M., Krzemien-Wolska, K., Starosta, P., Nowalany-Kozielska, E., Orzechowska, A., Szpot, M., Staszel, M., Almeida, S., Pereira, H., Brandão Alves, L., Miranda, R., Ribeiro, L., Costa, F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragão, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhães, P., Fontes, P., Leão, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Dan, G., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu-Andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Ioachim Popescu, M., Nistor, D., Sus, I., Coborosanu, O., Alina-Ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Vukmirovic, L., Radisavljevic, M., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Radovanovic, S., Kocijancic, A., Obrenovic-Kircanski, B., Kalimanovska Ostric, D., Simic, D., Jovanovic, I., Petrovic, I., Polovina, M., Vukicevic, M., Tomasevic, M., Mujovic, N., Radivojevic, N., Petrovic, O., Aleksandric, S., Kovacevic, V., Mijatovic, Z., Ivanovic, B., Tesic, M., Ristic, A., Vujisic-Tesic, B., Nedeljkovic, M., Karadzic, A., Uscumlic, A., Prodanovic, M., Zlatar, M., Asanin, M., Bisenic, B., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Backovic, S., Stevanovic, A., Andric, A., Pencic, B., Pavlovic-Kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric-Cupic, V., Djordjevic, D., Damjanovic, M., Zdravkovic, S., Topic, V., Stanojevic, D., Randjelovic, M., Jankovic-Tomasevic, R., Atanaskovic, V., Antic, S., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Markovic, S., Mijatovic, A., Tanasic, D., Radakovic, G., Peranovic, J., Panic-Jelic, N., Vujadinovic, O., Pajic, P., Bekic, S., Kovacevic, S., García Fernandez, A., Perez Cabeza, A., Anguita, M., Tercedor Sanchez, L., Mau, E., Loayssa, J., Ayarra, M., Carpintero, M., Roldán Rabadan, I., Gil Ortega, M., Tello Montoliu, A., Orenes Piñero, E., Manzano Fernández, S., Marín, F., Romero Aniorte, A., Veliz Martínez, A., Quintana Giner, M., Ballesteros, G., Palacio, M., Alcalde, O., García-Bolao, I., Bertomeu Gonzalez, V., Otero-Raviña, F., García Seara, J., Gonzalez Juanatey, J., Dayal, N., Maziarski, P., Gentil-Baron, P., Koç, M., Onrat, E., Dural, I.E., Yilmaz, K., Özin, B., Tan Kurklu, S., Atmaca, Y., Canpolat, U., Tokgozoglu, L., Dolu, A.K., Demirtas, B., Sahin, D., Ozcan Celebi, O., Gagirci, G., Turk, U.O., Ari, H., Polat, N., Toprak, N., Sucu, M., Akin Serdar, O., Taha Alper, A., Kepez, A., Yuksel, Y., Uzunselvi, A., Yuksel, S., Sahin, M., Kayapinar, O., Ozcan, T., Kaya, H., Yilmaz, M.B., Kutlu, M., Demir, M., Gibbs, C., Kaminskiene, S., Bryce, M., Skinner, A., Belcher, G., Hunt, J., Stancombe, L., Holbrook, B., Peters, C., Tettersell, S., Shantsila, A., Lane, D., Senoo, K., Proietti, M., Russell, K., Domingos, P., Hussain, S., Partridge, J., Haynes, R., Bahadur, S., Brown, R., McMahon, S., McDonald, J., Balachandran, K., Singh, R., Garg, S., Desai, H., Davies, K., Goddard, W., Galasko, G., Rahman, I., Chua, Y., Payne, O., Preston, S., Brennan, O., Pedley, L., Whiteside, C., Dickinson, C., Brown, J., Jones, K., Benham, L., Brady, R., Buchanan, L., Ashton, A., Crowther, H., Fairlamb, H., Thornthwaite, S., Relph, C., McSkeane, A., Poultney, U., Kelsall, N., Rice, P., Wilson, T., Wrigley, M., Kaba, R., Patel, T., Young, E., Law, J., Runnett, C., Thomas, H., McKie, H., Fuller, J., Pick, S., Sharp, A., Hunt, A., Thorpe, K., Hardman, C., Cusack, E., Adams, L., Hough, M., Keenan, S., Bowring, A., Watts, J., Zaman, J., Goffin, K., Nutt, H., Beerachee, Y., Featherstone, J., Mills, C., Pearson, J., Stephenson, L., Grant, S., Wilson, A., Hawksworth, C., Alam, I., Robinson, M., Ryan, S., Egdell, R., Gibson, E., Holland, M., Leonard, D., Mishra, B., Ahmad, S., Randall, H., Hill, J., Reid, L., George, M., McKinley, S., Brockway, L., Milligan, W., Sobolewska, J., Muir, J., Tuckis, L., Winstanley, L., Jacob, P., Kaye, S., Morby, L., Jan, A., Sewell, T., Boos, C., Wadams, B., Cope, C., Jefferey, P., Andrews, N., Getty, A., Suttling, A., Turner, C., Hudson, K., Austin, R., Howe, S., Iqbal, R., Gandhi, N., Brophy, K., Mirza, P., Willard, E., Collins, S., Ndlovu, N., Subkovas, E., Karthikeyan, V., Waggett, L., Wood, A., Bolger, A., Stockport, J., Evans, L., Harman, E., Starling, J., Williams, L., Saul, V., Sinha, M., Bell, L., Tudgay, S., Kemp, S., Frost, L., Ingram, T., Loughlin, A., Adams, C., Adams, M., Hurford, F., Owen, C., Miller, C., Donaldson, D., Tivenan, H., Button, H., Nasser, A., Jhagra, O., Stidolph, B., Brown, C., Livingstone, C., Duffy, M., Madgwick, P., Roberts, P., Greenwood, E., Fletcher, L., Beveridge, M., Earles, S., McKenzie, D., Beacock, D., Dayer, M., Seddon, M., Greenwell, D., Luxton, F., Venn, F., Mills, H., Rewbury, J., James, K., Roberts, K., Tonks, L., Felmeden, D., Taggu, W., Summerhayes, A., Hughes, D., Sutton, J., Felmeden, L., Khan, M., Walker, E., Norris, L., O'Donohoe, L., Mozid, A., Dymond, H., Lloyd-Jones, H., Saunders, G., Simmons, D., Coles, D., Cotterill, D., Beech, S., Kidd, S., Wrigley, B., Petkar, S., Smallwood, A., Jones, R., Radford, E., Milgate, S., Metherell, S., Cottam, V., Buckley, C., Broadley, A., Wood, D., Allison, J., Rennie, K., Balian, L., Howard, L., Pippard, L., Board, S., Pitt-Kerby, T., Vitolo, Marco, Malavasi, Vincenzo L., Proietti, Marco, Diemberger, Igor, Fauchier, Laurent, Marin, Francisco, Nabauer, Michael, Potpara, Tatjana S., Dan, Gheorghe-Andrei, Kalarus, Zbigniew, Tavazzi, Luigi, Maggioni, Aldo Pietro, Lane, Deirdre A., Lip, Gregory Y.H., and Boriani, Giuseppe
Published: 2022
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5. AB0607 SOLUBLE INTERLEUKIN-33 RECEPTOR (sST-2) - A NOVEL MARKER FOR ASSESSING CARDIOVASCULAR RISK IN RHEUMATOID ARTHRITIS

Author: Patschan, S., primary, Claus, I., additional, Hoffmeister, M., additional, Remus, C., additional, Ritter, O., additional, and Patschan, D., additional
Published: 2024
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6. Enhancing citizen science impact in environmental monitoring: Targeted engagement strategies with stakeholder groups

Author: Koedel, Uta, Dietrich, Peter, Herrmann, Thora Martina, Liang, Christine, Ritter, O., Roettenbacher, J., Schuetze, Fabian Michael, Schuetze, Sophia, Thoboell, J.C., Schuetze, Claudia, Koedel, Uta, Dietrich, Peter, Herrmann, Thora Martina, Liang, Christine, Ritter, O., Roettenbacher, J., Schuetze, Fabian Michael, Schuetze, Sophia, Thoboell, J.C., and Schuetze, Claudia
Abstract: Understanding the motivations and benefits of citizen science (CS) participants is critical to the success of environmental science projects that rely on data collection from engaged citizens. Tailored communication with citizen scientists is essential, leading to the need to target specific societal groups for extensive and high-quality data sets. The purpose of the study was to apply marketing concepts such as stakeholder analysis, value proposition canvas (VPC), and key performance indicators (KPIs) to CS projects. The study examined the extent to which these strategies can be applied to CS projects and add value, resulting in improved recruitment and retention of participants, as well as improved project management. The dynamic landscape of CS projects requires adapted business-oriented approaches supporting ongoing participation with high motivation, acknowledging community needs, and recognizing institutional scientists, akin to targeting potential customers. The case study focuses on the CityCLIM initiative, an EU-funded project collecting urban climate data, especially air temperature, using mobile weather stations. The CityCLIM VPC, analyzing stakeholder groups, facilitated tailored communication strategies by analyzing stakeholder groups and highlighting the effectiveness of the CS cycling initiative within the “Stadtradeln” program. Impact KPIs served as a roadmap for strategic refinement, while data quality KPIs identified deficiencies, guiding adjustments to the campaign. Applied marketing tools improved project planning, engagement, and evaluation, demonstrating the potential of this concept. Adapting marketing tools to recruitment and communication strategies benefits CS projects by targeting specific groups. The holistic integration of stakeholder analysis, VPC, and KPIs streamlines project management and creates a framework for sustainable success. This adaptation forms a robust toolkit for CS project coordinators, contributing to effective communic
Published: 2024

7. Enterococcus Faecalis in Endocarditis: Second Most Common Endocarditis Pathogen on the Rise? Data from the Brandenburg Endocarditis Registry

Author: Ostovar, R., additional, Schröter, F., additional, Kühnel, R.U. Dr. med., additional, Braun, C., additional, Seifi, Z. F., additional, Fritzsche, D., additional, Minden, H.H., additional, Ritter, O., additional, Dörr, G., additional, and Albes, J., additional
Published: 2024
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8. Association of cytokine patterns and clinical/laboratory parameters, medication and periodontal burden in patients with rheumatoid arthritis (RA)

Author: Patschan, S., Bothmann, L., Patschan, D., Henze, E., Schmalz, G., Ritter, O., and Ziebolz, D.
Published: 2020
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9. Effective treatment of electrical storm by a wearable cardioverter defibrillator in a patient with severely impaired left ventricular function after myocardial infarction: a case report

Author: Andresen, Henrike, Sasko, B., Patschan, D., Pagonas, N., and Ritter, O.
Published: 2021
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10. Vector constants of motion for time-dependent Kepler and isotropic harmonic oscillator potentials

Author: Ritter, O. M., Santos, F. C., and Tort, A. C.
Subjects: Physics - Classical Physics, Physics - General Physics
Abstract: A method of obtaining vector constants of motion for time-independent as well as time-dependent central fields is discussed. Some well-established results are rederived in this alternative way and new ones obtained., Comment: 18 pages, no figures, regular Latex article format
Published: 2000
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11. Clinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry

Author: Romiti, Giulio Francesco, Proietti, Marco, Vitolo, Marco, Bonini, Niccolò, Fawzy, Ameenathul Mazaya, Ding, Wern Yew, Fauchier, Laurent, Marin, Francisco, Nabauer, Michael, Dan, Gheorghe Andrei, Potpara, Tatjana S., Boriani, Giuseppe, Lip, Gregory Y. H., Tavazzi, L., Maggioni, A. P., Kalarus, Z., Ferrari, R., Shantsila, A., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., García Bolao, I., Piot, O., Etsadashvili, K., Simantirakis, E. N., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K., Erglis, A., Poposka, L., Burg, M. R., Crijns, H., Erküner, Atar, D., Lenarczyk, R., Oliveira, M. Martins, Shah, D., Serdechnaya, E., Diker, E., Lane, D., Zëra, E., Ekmekçiu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., el Husseini, Z., Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., van Genechten, G., Heidbuchel, H., Boussy, T., de Coninck, M., van Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., van Hauwaert, B., Kuppens, C., Faes, D., van Lier, D., van Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska-Georgieva, S., Slavcheva, S., Yotov, Y., Kubíčková, M., Joensen, A. Marni, Gammelmark, A., Rasmussen, L. Hvilsted, Dinesen, P., Venø, S. Krogh, Sorensen, B., Korsgaard, A., Andersen, K., Hellum, C. 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L., Mussagaliyeva, A., Ahyt, B., Salihova, Z., Koshum-Bayeva, K., Kerimkulova, A., Bairamukova, A., Lurina, B., Zuzans, R., Jegere, S., Mintale, I., Kupics, K., Jubele, K., Kalejs, O., Vanhear, K., Burg, M., Cachia, M., Abela, E., Warwicker, S., Tabone, T., Xuereb, R., Asanovic, D., Drakalovic, D., Vukmirovic, M., Pavlovic, N., Music, L., Bulatovic, N., Boskovic, A., Uiterwaal, H., Bijsterveld, N., de Groot, J., Neefs, J., van den Berg, N., Piersma, F., Wilde, A., Hagens, V., van Es, J., van Opstal, J., van Rennes, B., Verheij, H., Breukers, W., Tjeerdsma, G., Nijmeijer, R., Wegink, D., Binnema, R., Said, S., Philippens, S., van Doorn, W., Szili-Torok, T., Bhagwandien, R., Janse, P., Muskens, A., van Eck, M., Gevers, R., van der Ven, N., Duygun, A., Rahel, B., Meeder, J., Vold, A., Holst Hansen, C., Engset, I., Dyduch-Fejklowicz, B., Koba, E., Cichocka, M., Sokal, A., Kubicius, A., Pruchniewicz, E., Kowalik-Sztylc, A., Czapla, W., Mróz, I., Kozlowski, M., Pawlowski, T., Tendera, M., Winiarska-Filipek, A., Fidyk, A., Slowikowski, A., Haberka, M., Lachor-Broda, M., Biedron, M., Gasior, Z., Kołodziej, M., Janion, M., Gorczyca-Michta, I., Wozakowska-Kaplon, B., Stasiak, M., Jakubowski, P., Ciurus, T., Drozdz, J., Simiera, M., Zajac, P., Wcislo, T., Zycinski, P., Kasprzak, J., Olejnik, A., Harc-Dyl, E., Miarka, J., Pasieka, M., Ziemińska-Łuć, M., Bujak, W., Śliwiński, A., Grech, A., Morka, J., Petrykowska, K., Prasał, M., Hordyński, G., Feusette, P., Lipski, P., Wester, A., Streb, W., Romanek, J., Woźniak, P., Chlebuś, M., Szafarz, P., Stanik, W., Zakrzewski, M., Kaźmierczak, J., Przybylska, A., Skorek, E., Błaszczyk, H., Stępień, M., Szabowski, S., Krysiak, W., Szymańska, M., Karasiński, J., Blicharz, J., Skura, M., Hałas, K., Michalczyk, L., Orski, Z., Krzyżanowski, K., Skrobowski, A., Zieliński, L., Tomaszewska-Kiecana, M., Dłużniewski, M., Kiliszek, M., Peller, M., Budnik, M., Balsam, P., Opolski, G., Tymińska, A., Ozierański, K., Wancerz, A., Borowiec, A., Majos, E., Dabrowski, R., Szwed, H., Musialik-Lydka, A., Leopold-Jadczyk, A., Jedrzejczyk-Patej, E., Koziel, M., Mazurek, M., Krzemien-Wolska, K., Starosta, P., Nowalany-Kozielska, E., Orzechowska, A., Szpot, M., Staszel, M., Almeida, S., Pereira, H., Brandão Alves, L., Miranda, R., Ribeiro, L., Costa, F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragão, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhães, P., Fontes, P., Leão, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Dan, G., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu-Andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Popescu, M. Ioachim, Nistor, D., Sus, I., Coborosanu, O., Alina-Ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Polovina, M., Vujisic-Tesic, B., Nedeljkovic, M., Zlatar, M., Asanin, M., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Stevanovic, A., Andric, A., Pencic, B., Pavlovic-Kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric-Cupic, V., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Markovic, S., Kovacevic, S., García Fernandez, A., Perez Cabeza, A., Anguita, M., Tercedor Sanchez, L., Mau, E., Loayssa, J., Ayarra, M., Carpintero, M., Roldán Rabadan, I., Ortega, M. Gil, Tello Montoliu, A., Orenes Piñero, E., Manzano Fernández, S., Marín, F., Romero Aniorte, A., Veliz Martínez, A., Quintana Giner, M., Ballesteros, G., Palacio, M., Alcalde, O., García-Bolao, I., Bertomeu Gonzalez, V., Otero-Raviña, F., García Seara, J., Gonzalez Juanatey, J., Dayal, N., Maziarski, P., Gentil-Baron, P., Koç, M., Onrat, E., Dural, I. E., Yilmaz, K., Özin, B., Kurklu, S. Tan, Atmaca, Y., Canpolat, U., Tokgozoglu, L., Dolu, A. K., Demirtas, B., Sahin, D., Ozcan Celebi, O., Gagirci, G., Turk, U. O., Ari, H., Polat, N., Toprak, N., Sucu, M., Akin Serdar, O., Taha Alper, A., Kepez, A., Yuksel, Y., Uzunselvi, A., Yuksel, S., Sahin, M., Kayapinar, O., Ozcan, T., Kaya, H., Yilmaz, M. 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Grant, S., Wilson, A., Hawksworth, C., Alam, I., Robinson, M., Ryan, S., Egdell, R., Gibson, E., Holland, M., Leonard, D., Mishra, B., Ahmad, S., Randall, H., Hill, J., Reid, L., George, M., McKinley, S., Brockway, L., Milligan, W., Sobolewska, J., Muir, J., Tuckis, L., Winstanley, L., Jacob, P., Kaye, S., Morby, L., Jan, A., Sewell, T., Boos, C., Wadams, B., Cope, C., Jefferey, P., Andrews, N., Getty, A., Suttling, A., Turner, C., Hudson, K., Austin, R., Howe, S., Iqbal, R., Gandhi, N., Brophy, K., Mirza, P., Willard, E., Collins, S., Ndlovu, N., Subkovas, E., Karthikeyan, V., Waggett, L., Wood, A., Bolger, A., Stockport, J., Evans, L., Harman, E., Starling, J., Williams, L., Saul, V., Sinha, M., Bell, L., Tudgay, S., Kemp, S., Frost, L., Ingram, T., Loughlin, A., Adams, C., Adams, M., Hurford, F., Owen, C., Miller, C., Donaldson, D., Tivenan, H., Button, H., Nasser, A., Jhagra, O., Stidolph, B., Brown, C., Livingstone, C., Duffy, M., Madgwick, P., Roberts, P., Greenwood, E., Fletcher, L., Beveridge, M., Earles, S., McKenzie, D., Beacock, D., Dayer, M., Seddon, M., Greenwell, D., Luxton, F., Venn, F., Mills, H., Rewbury, J., James, K., Roberts, K., Tonks, L., Felmeden, D., Taggu, W., Summerhayes, A., Hughes, D., Sutton, J., Felmeden, L., Khan, M., Walker, E., Norris, L., O’Donohoe, L., Mozid, A., Dymond, H., Lloyd-Jones, H., Saunders, G., Simmons, D., Coles, D., Cotterill, D., Beech, S., Kidd, S., Wrigley, B., Petkar, S., Smallwood, A., Jones, R., Radford, E., Milgate, S., Metherell, S., Cottam, V., Buckley, C., Broadley, A., Wood, D., Allison, J., Rennie, K., Balian, L., Howard, L., Pippard, L., Board, S., Pitt-Kerby, T., Romiti G.F., Proietti M., Vitolo M., Bonini N., Fawzy A.M., Ding W.Y., Fauchier L., Marin F., Nabauer M., Dan G.A., Potpara T.S., Boriani G., Lip G.Y.H., Tavazzi L., Maggioni A.P., Kalarus Z., Ferrari R., Shantsila A., Goda A., Mairesse G., Shalganov T., Antoniades L., Taborsky M., Riahi S., Muda P., Garcia Bolao I., Piot O., Etsadashvili K., Simantirakis E.N., Haim M., Azhari A., Najafian J., Santini M., Mirrakhimov E., Kulzida K., Erglis A., Poposka L., Burg M.R., Crijns H., Erkuner O., Atar D., Lenarczyk R., Oliveira M.M., Shah D., Serdechnaya E., Diker E., Lane D., Zera E., Ekmekciu U., Paparisto V., Tase M., Gjergo H., Dragoti J., Ciutea M., Ahadi N., el Husseini Z., Raepers M., Leroy J., Haushan P., Jourdan A., Lepiece C., Desteghe L., Vijgen J., Koopman P., Van Genechten G., Heidbuchel H., Boussy T., De Coninck M., Van Eeckhoutte H., Bouckaert N., Friart A., Boreux J., Arend C., Evrard P., Stefan L., Hoffer E., Herzet J., Massoz M., Celentano C., Sprynger M., Pierard L., Melon P., Van Hauwaert B., Kuppens C., Faes D., Van Lier D., Van Dorpe A., Gerardy A., Deceuninck O., Xhaet O., Dormal F., Ballant E., Blommaert D., Yakova D., Hristov M., Yncheva T., Stancheva N., Tisheva S., Tokmakova M., Nikolov F., Gencheva D., Kunev B., Stoyanov M., Marchov D., Gelev V., Traykov V., Kisheva A., Tsvyatkov H., Shtereva R., Bakalska-Georgieva S., Slavcheva S., Yotov Y., Kubickova M., Joensen A.M., Gammelmark A., Rasmussen L.H., Dinesen P., Veno S.K., Sorensen B., Korsgaard A., Andersen K., Hellum C.F., Svenningsen A., Nyvad O., Wiggers P., May O., Aarup A., Graversen B., Jensen L., Andersen M., Svejgaard M., Vester S., Hansen S., Lynggaard V., Ciudad M., Vettus R., Maestre A., Castano S., Cheggour S., Poulard J., Mouquet V., Leparree S., Bouet J., Taieb J., Doucy A., Duquenne H., Furber A., Dupuis J., Rautureau J., Font M., Damiano P., Lacrimini M., Abalea J., Boismal S., Menez T., Mansourati J., Range G., Gorka H., Laure C., Vassaliere C., Elbaz N., Lellouche N., Djouadi K., Roubille F., Dietz D., Davy J., Granier M., Winum P., Leperchois-Jacquey C., Kassim H., Marijon E., Le Heuzey J., Fedida J., Maupain C., Himbert C., Gandjbakhch E., Hidden-Lucet F., Duthoit G., Badenco N., Chastre T., Waintraub X., Oudihat M., Lacoste J., Stephan C., Bader H., Delarche N., Giry L., Arnaud D., Lopez C., Boury F., Brunello I., Lefevre M., Mingam R., Haissaguerre M., Le Bidan M., Pavin D., Le Moal V., Leclercq C., Beitar T., Martel I., Schmid A., Sadki N., Romeyer-Bouchard C., Da Costa A., Arnault I., Boyer M., Piat C., Lozance N., Nastevska S., Doneva A., Fortomaroska Milevska B., Sheshoski B., Petroska K., Taneska N., Bakrecheski N., Lazarovska K., Jovevska S., Ristovski V., Antovski A., Lazarova E., Kotlar I., Taleski J., Kedev S., Zlatanovik N., Jordanova S., Bajraktarova Proseva T., Doncovska S., Maisuradze D., Esakia A., Sagirashvili E., Lartsuliani K., Natelashvili N., Gumberidze N., Gvenetadze R., Gotonelia N., Kuridze N., Papiashvili G., Menabde I., Gloggler S., Napp A., Lebherz C., Romero H., Schmitz K., Berger M., Zink M., Koster S., Sachse J., Vonderhagen E., Soiron G., Mischke K., Reith R., Schneider M., Rieker W., Boscher D., Taschareck A., Beer A., Oster D., Ritter O., Adamczewski J., Walter S., Frommhold A., Luckner E., Richter J., Schellner M., Landgraf S., Bartholome S., Naumann R., Schoeler J., Westermeier D., William F., Wilhelm K., Maerkl M., Oekinghaus R., Denart M., Kriete M., Tebbe U., Scheibner T., Gruber M., Gerlach A., Beckendorf C., Anneken L., Arnold M., Lengerer S., Bal Z., Uecker C., Fortsch H., Fechner S., Mages V., Martens E., Methe H., Schmidt T., Schaeffer B., Hoffmann B., Moser J., Heitmann K., Willems S., Klaus C., Lange I., Durak M., Esen E., Mibach F., Mibach H., Utech A., Gabelmann M., Stumm R., Landle V., Gartner C., Goerg C., Kaul N., Messer S., Burkhardt D., Sander C., Orthen R., Kaes S., Baumer A., Dodos F., Barth A., Schaeffer G., Gaertner J., Winkler J., Fahrig A., Aring J., Wenzel I., Steiner S., Kliesch A., Kratz E., Winter K., Schneider P., Haag A., Mutscher I., Bosch R., Taggeselle J., Meixner S., Schnabel A., Shamalla A., Hotz H., Korinth A., Rheinert C., Mehltretter G., Schon B., Schon N., Starflinger A., Englmann E., Baytok G., Laschinger T., Ritscher G., Gerth A., Dechering D., Eckardt L., Kuhlmann M., Proskynitopoulos N., Brunn J., Foth K., Axthelm C., Hohensee H., Eberhard K., Turbanisch S., Hassler N., Koestler A., Stenzel G., Kschiwan D., Schwefer M., Neiner S., Hettwer S., Haeussler-Schuchardt M., Degenhardt R., Sennhenn S., Brendel M., Stoehr A., Widjaja W., Loehndorf S., Logemann A., Hoskamp J., Grundt J., Block M., Ulrych R., Reithmeier A., Panagopoulos V., Martignani C., Bernucci D., Fantecchi E., Diemberger I., Ziacchi M., Biffi M., Cimaglia P., Frisoni J., Giannini I., Boni S., Fumagalli S., Pupo S., Di Chiara A., Mirone P., Pesce F., Zoccali C., Malavasi V.L., Mussagaliyeva A., Ahyt B., Salihova Z., Koshum-Bayeva K., Kerimkulova A., Bairamukova A., Lurina B., Zuzans R., Jegere S., Mintale I., Kupics K., Jubele K., Kalejs O., Vanhear K., Burg M., Cachia M., Abela E., Warwicker S., Tabone T., Xuereb R., Asanovic D., Drakalovic D., Vukmirovic M., Pavlovic N., Music L., Bulatovic N., Boskovic A., Uiterwaal H., Bijsterveld N., De Groot J., Neefs J., van den Berg N., Piersma F., Wilde A., Hagens V., Van Es J., Van Opstal J., Van Rennes B., Verheij H., Breukers W., Tjeerdsma G., Nijmeijer R., Wegink D., Binnema R., Said S., Philippens S., van Doorn W., Szili-Torok T., Bhagwandien R., Janse P., Muskens A., van Eck M., Gevers R., van der Ven N., Duygun A., Rahel B., Meeder J., Vold A., Holst Hansen C., Engset I., Dyduch-Fejklowicz B., Koba E., Cichocka M., Sokal A., Kubicius A., Pruchniewicz E., Kowalik-Sztylc A., Czapla W., Mroz I., Kozlowski M., Pawlowski T., Tendera M., Winiarska-Filipek A., Fidyk A., Slowikowski A., Haberka M., Lachor-Broda M., Biedron M., Gasior Z., Kolodziej M., Janion M., Gorczyca-Michta I., Wozakowska-Kaplon B., Stasiak M., Jakubowski P., Ciurus T., Drozdz J., Simiera M., Zajac P., Wcislo T., Zycinski P., Kasprzak J., Olejnik A., Harc-Dyl E., Miarka J., Pasieka M., Zieminska-Luc M., Bujak W., Sliwinski A., Grech A., Morka J., Petrykowska K., Prasal M., Hordynski G., Feusette P., Lipski P., Wester A., Streb W., Romanek J., Wozniak P., Chlebus M., Szafarz P., Stanik W., Zakrzewski M., Kazmierczak J., Przybylska A., Skorek E., Blaszczyk H., Stepien M., Szabowski S., Krysiak W., Szymanska M., Karasinski J., Blicharz J., Skura M., Halas K., Michalczyk L., Orski Z., Krzyzanowski K., Skrobowski A., Zielinski L., Tomaszewska-Kiecana M., Dluzniewski M., Kiliszek M., Peller M., Budnik M., Balsam P., Opolski G., Tyminska A., Ozieranski K., Wancerz A., Borowiec A., Majos E., Dabrowski R., Szwed H., Musialik-Lydka A., Leopold-Jadczyk A., Jedrzejczyk-Patej E., Koziel M., Mazurek M., Krzemien-Wolska K., Starosta P., Nowalany-Kozielska E., Orzechowska A., Szpot M., Staszel M., Almeida S., Pereira H., Brandao Alves L., Miranda R., Ribeiro L., Costa F., Morgado F., Carmo P., Galvao Santos P., Bernardo R., Adragao P., Ferreira da Silva G., Peres M., Alves M., Leal M., Cordeiro A., Magalhaes P., Fontes P., Leao S., Delgado A., Costa A., Marmelo B., Rodrigues B., Moreira D., Santos J., Santos L., Terchet A., Darabantiu D., Mercea S., Turcin Halka V., Pop Moldovan A., Gabor A., Doka B., Catanescu G., Rus H., Oboroceanu L., Bobescu E., Popescu R., Dan A., Buzea A., Daha I., Dan G., Neuhoff I., Baluta M., Ploesteanu R., Dumitrache N., Vintila M., Daraban A., Japie C., Badila E., Tewelde H., Hostiuc M., Frunza S., Tintea E., Bartos D., Ciobanu A., Popescu I., Toma N., Gherghinescu C., Cretu D., Patrascu N., Stoicescu C., Udroiu C., Bicescu G., Vintila V., Vinereanu D., Cinteza M., Rimbas R., Grecu M., Cozma A., Boros F., Ille M., Tica O., Tor R., Corina A., Jeewooth A., Maria B., Georgiana C., Natalia C., Alin D., Dinu-Andrei D., Livia M., Daniela R., Larisa R., Umaar S., Tamara T., Popescu M.I., Nistor D., Sus I., Coborosanu O., Alina-Ramona N., Dan R., Petrescu L., Ionescu G., Vacarescu C., Goanta E., Mangea M., Ionac A., Mornos C., Cozma D., Pescariu S., Solodovnicova E., Soldatova I., Shutova J., Tjuleneva L., Zubova T., Uskov V., Obukhov D., Rusanova G., Isakova N., Odinsova S., Arhipova T., Kazakevich E., Zavyalova O., Novikova T., Riabaia I., Zhigalov S., Drozdova E., Luchkina I., Monogarova Y., Hegya D., Rodionova L., Nevzorova V., Lusanova O., Arandjelovic A., Toncev D., Milanov M., Sekularac N., Zdravkovic M., Hinic S., Dimkovic S., Acimovic T., Saric J., Polovina M., Vujisic-Tesic B., Nedeljkovic M., Zlatar M., Asanin M., Vasic V., Popovic Z., Djikic D., Sipic M., Peric V., Dejanovic B., Milosevic N., Stevanovic A., Andric A., Pencic B., Pavlovic-Kleut M., Celic V., Pavlovic M., Petrovic M., Vuleta M., Petrovic N., Simovic S., Savovic Z., Milanov S., Davidovic G., Iric-Cupic V., Simonovic D., Stojanovic M., Stojanovic S., Mitic V., Ilic V., Petrovic D., Deljanin Ilic M., Ilic S., Stoickov V., Markovic S., Kovacevic S., Garcia Fernandez A., Perez Cabeza A., Anguita M., Tercedor Sanchez L., Mau E., Loayssa J., Ayarra M., Carpintero M., Roldan Rabadan I., Ortega M.G., Tello Montoliu A., Orenes Pinero E., Manzano Fernandez S., Romero Aniorte A., Veliz Martinez A., Quintana Giner M., Ballesteros G., Palacio M., Alcalde O., Garcia-Bolao I., Bertomeu Gonzalez V., Otero-Ravina F., Garcia Seara J., Gonzalez Juanatey J., Dayal N., Maziarski P., Gentil-Baron P., Koc M., Onrat E., Dural I.E., Yilmaz K., Ozin B., Kurklu S.T., Atmaca Y., Canpolat U., Tokgozoglu L., Dolu A.K., Demirtas B., Sahin D., Ozcan Celebi O., Gagirci G., Turk U.O., Ari H., Polat N., Toprak N., Sucu M., Akin Serdar O., Taha Alper A., Kepez A., Yuksel Y., Uzunselvi A., Yuksel S., Sahin M., Kayapinar O., Ozcan T., Kaya H., Yilmaz M.B., Kutlu M., Demir M., Gibbs C., Kaminskiene S., Bryce M., Skinner A., Belcher G., Hunt J., Stancombe L., Holbrook B., Peters C., Tettersell S., Senoo K., Russell K., Domingos P., Hussain S., Partridge J., Haynes R., Bahadur S., Brown R., McMahon S., McDonald J., Balachandran K., Singh R., Garg S., Desai H., Davies K., Goddard W., Galasko G., Rahman I., Chua Y., Payne O., Preston S., Brennan O., Pedley L., Whiteside C., Dickinson C., Brown J., Jones K., Benham L., Brady R., Buchanan L., Ashton A., Crowther H., Fairlamb H., Thornthwaite S., Relph C., McSkeane A., Poultney U., Kelsall N., Rice P., Wilson T., Wrigley M., Kaba R., Patel T., Young E., Law J., Runnett C., Thomas H., McKie H., Fuller J., Pick S., Sharp A., Hunt A., Thorpe K., Hardman C., Cusack E., Adams L., Hough M., Keenan S., Bowring A., Watts J., Zaman J., Goffin K., Nutt H., Beerachee Y., Featherstone J., Mills C., Pearson J., Stephenson L., Grant S., Wilson A., Hawksworth C., Alam I., Robinson M., Ryan S., Egdell R., Gibson E., Holland M., Leonard D., Mishra B., Ahmad S., Randall H., Hill J., Reid L., George M., McKinley S., Brockway L., Milligan W., Sobolewska J., Muir J., Tuckis L., Winstanley L., Jacob P., Kaye S., Morby L., Jan A., Sewell T., Boos C., Wadams B., Cope C., Jefferey P., Andrews N., Getty A., Suttling A., Turner C., Hudson K., Austin R., Howe S., Iqbal R., Gandhi N., Brophy K., Mirza P., Willard E., Collins S., Ndlovu N., Subkovas E., Karthikeyan V., Waggett L., Wood A., Bolger A., Stockport J., Evans L., Harman E., Starling J., Williams L., Saul V., Sinha M., Bell L., Tudgay S., Kemp S., Frost L., Ingram T., Loughlin A., Adams C., Adams M., Hurford F., Owen C., Miller C., Donaldson D., Tivenan H., Button H., Nasser A., Jhagra O., Stidolph B., Brown C., Livingstone C., Duffy M., Madgwick P., Roberts P., Greenwood E., Fletcher L., Beveridge M., Earles S., McKenzie D., Beacock D., Dayer M., Seddon M., Greenwell D., Luxton F., Venn F., Mills H., Rewbury J., James K., Roberts K., Tonks L., Felmeden D., Taggu W., Summerhayes A., Hughes D., Sutton J., Felmeden L., Khan M., Walker E., Norris L., O'Donohoe L., Mozid A., Dymond H., Lloyd-Jones H., Saunders G., Simmons D., Coles D., Cotterill D., Beech S., Kidd S., Wrigley B., Petkar S., Smallwood A., Jones R., Radford E., Milgate S., Metherell S., Cottam V., Buckley C., Broadley A., Wood D., Allison J., Rennie K., Balian L., Howard L., Pippard L., Board S., Pitt-Kerby T., Pulmonary medicine, Rehabilitation medicine, Internal medicine, Radiology and nuclear medicine, Cardiology, Pulmonary Medicine, General Practice, ACS - Heart failure & arrhythmias, Medical Oncology, Erasmus School of Health Policy & Management, Radiotherapy, Department of Technology and Operations Management, Virology, Erasmus School of Social and Behavioural Sciences, Child and Adolescent Psychiatry / Psychology, Internal Medicine, Tax Law, Epidemiology, Neurosciences, Rheumatology, Erasmus School of Economics, Department of Business-Society Management, Pediatrics, Erasmus MC other, Orthopedics and Sports Medicine, Intensive Care, Department of Marketing Management, Clinical Genetics, Surgery, Econometrics, Research & Education, Radiology & Nuclear Medicine, Neurosurgery, Psychiatry, Department of Psychology, Education and Child Studies, Plastic and Reconstructive Surgery and Hand Surgery, Dermatology, Public Health, Gastroenterology & Hepatology, Erasmus School of Law, and Sociology
Subjects: Registrie, Atrial Fibrillation/drug therapy, Integrated management, Risk Factor, Atrial fibrillation, Clinical complexity, Outcomes, Anticoagulants, Humans, Registries, Risk Factors, Atrial Fibrillation, Stroke, Anticoagulant, General Medicine, Anticoagulants/therapeutic use, Stroke/complications, Outcome, Human
Abstract: Background Clinical complexity is increasingly prevalent among patients with atrial fibrillation (AF). The ‘Atrial fibrillation Better Care’ (ABC) pathway approach has been proposed to streamline a more holistic and integrated approach to AF care; however, there are limited data on its usefulness among clinically complex patients. We aim to determine the impact of ABC pathway in a contemporary cohort of clinically complex AF patients. Methods From the ESC-EHRA EORP-AF General Long-Term Registry, we analysed clinically complex AF patients, defined as the presence of frailty, multimorbidity and/or polypharmacy. A K-medoids cluster analysis was performed to identify different groups of clinical complexity. The impact of an ABC-adherent approach on major outcomes was analysed through Cox-regression analyses and delay of event (DoE) analyses. Results Among 9966 AF patients included, 8289 (83.1%) were clinically complex. Adherence to the ABC pathway in the clinically complex group reduced the risk of all-cause death (adjusted HR [aHR]: 0.72, 95%CI 0.58–0.91), major adverse cardiovascular events (MACEs; aHR: 0.68, 95%CI 0.52–0.87) and composite outcome (aHR: 0.70, 95%CI: 0.58–0.85). Adherence to the ABC pathway was associated with a significant reduction in the risk of death (aHR: 0.74, 95%CI 0.56–0.98) and composite outcome (aHR: 0.76, 95%CI 0.60–0.96) also in the high-complexity cluster; similar trends were observed for MACEs. In DoE analyses, an ABC-adherent approach resulted in significant gains in event-free survival for all the outcomes investigated in clinically complex patients. Based on absolute risk reduction at 1 year of follow-up, the number needed to treat for ABC pathway adherence was 24 for all-cause death, 31 for MACEs and 20 for the composite outcome. Conclusions An ABC-adherent approach reduces the risk of major outcomes in clinically complex AF patients. Ensuring adherence to the ABC pathway is essential to improve clinical outcomes among clinically complex AF patients.
Published: 2022
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12. Effets des bronchodilatateurs à longue durée d’action sur le contrôle autonome cardiaque dans la BPCO

Author: Elhage, S., primary, Laurent, L., additional, Diallo, K., additional, Bouhaddi, M., additional, Ritter, O., additional, Clairet, A.-L., additional, Puyraveau, M., additional, Soumagne, T., additional, and Degano, B., additional
Published: 2023
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13. Infective Endocarditis: Do Registry Data Help Improve Treatment Strategies?

Author: Ostovar, R., additional, Schröter, F., additional, Zinab, F. Seifi, additional, Fritzsche, D., additional, Hartrumpf, M., additional, Chopsonidou, S., additional, Minden, H. H., additional, Lasheen, N., additional, Ritter, O., additional, Braun, C., additional, Dörr, G., additional, and Albes, J., additional
Published: 2023
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14. Incidence, évolution à un an et facteurs de risque de faiblesse du muscle inspiratoire après un séjour en réanimation pour COVID-19

Author: Karakaya, M., primary, Claude, F., additional, Eberst, G., additional, Laurent, L., additional, Ritter, O., additional, Meurisse, A., additional, Roux-Claude, P., additional, Plion, M., additional, Hordequin, L., additional, Winiszewski, H., additional, Pili-Floury, S., additional, Barnig, C., additional, and Westeel, V., additional
Published: 2023
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15. Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice

Author: Jansch, M., Lubomirov, L.T., Trum, M., Williams, T., Schmitt, J., Schuh, K., Qadri, F., Maier, L.S., Bader, M., and Ritter, O.
Subjects: Cardiovascular and Metabolic Diseases
Abstract: Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds are pathological and can lead to sudden cardiac death. We here focus on the ion channel modulator nitric oxide synthase 1 adaptor protein (Nos1ap). Whole-cell patch-clamp measurements of a conditional transgenic mouse model exhibiting cardiac specific Nos1ap over-expression revealed a Nos1ap-dependent increase of L-type calcium channel nitrosylation, which led to increased susceptibility to ventricular tachycardias associated with a decrease in QT duration and shortening of APD(90) duration. Survival was significantly reduced (60% after 12 weeks vs. 100% in controls). Examination of the structural features of the hearts of transgenic mice revealed constant heart dimensions and wall thickness without abnormal fibrosis content or BNP production after three months of Nos1ap over-expression compared to controls. Nos1ap over-expression did not alter cGMP production or ROS concentration. Our study showed that myocardial over-expression of Nos1ap leads to shortening of the QT interval and reduces survival rate of the transgenic animals, perhaps via development of ventricular arrhythmias. We conclude that Nos1ap overexpression causes targeted subcellular localization of Nos1 to the CaV1.2 with a subsequent decrease of ADP(90) and the QT interval. This causes detrimental cardiac arrhythmias in the transgenic mice.
Published: 2023

16. The Small-Scale Variability of Solar Radiation (S2VSR) Campaign – Overview and first Results

Author: Deneke, H., Macke, A., Redemann, J., Flynn, C., Ritsche, M., Saint-Drenan, Y., Witthuhn, J., Ritter, O., Heidinger, A., Lamkin, B., Foster, M., Walther, A., Romps, D., and Öktem, R.
Abstract: The solar radiation incident at the earth surface is a driving component of the surface energy budget. It often exhibits significant small-scale variability due to its modulation by clouds, in particular for shallow cumulus. This variability limits the representativity of tradiational point-like observations for extended spatial domains such as satellite pixels and model grid boxes. It also causes large fluctuations in power generation by photovoltaic systems.To better characterize this small-scale variability, TROPOS has developed a unique sensor network consisting of 100 autonomous pyranometers which record global radiation, temperature and relative humidity at a frequency of 1-Hz. It is thus capable of resolving fluctuations down to the second and decameter scale, as demonstrated for several past campaigns in Germany. The upcoming S2VSR campaign will deploy 60 of these stations at the Central Facility of the ARM Southern Great Plains site in the United States, distributed across a 6x6 km2 domain during summer 2023.The campaign will offer unique opportunities for the analysis of these data together with operational measurements at the ARM site. This specifically includes high-accuracy surface radiation, active cloud profiling, and the Clouds Optically Gridded by Stereo 4-D cloud product. A comparison with satellite observations from geostationary (GOES-R ABI data at 1-min and 500-m resolution) and polar orbit (Sentinel-2 at 10m) is also planned. The overarching goal is an improved understanding of the small-scale variability and 3D radiative effects of solar radiation. This contribution will present first observations from the ongoing campaign, and give a perspective on future plans., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)
Published: 2023
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17. Object-based characterization of Tropical Trade Cumulus Clouds During the EUREC4A/ATOMIC Field Campaign using Sentinel-2 Observations

Author: Ritter, O., Bley, S., and Deneke, H.
Abstract: In January and February 2020, the joint EUREC4A/ATOMIC field campaign took place in the Tropical Atlantic near Barbados, with the goal to advance our understanding of the interplay between clouds, convection and circulation, including their role in climate change. Within the scope of this campaign, several unique satellite-based datasets have been collected, including very high-spatial resolution multispectral images with 10x10m2 pixel size acquired by polar-orbiting Copernicus Sentinel-2 satellites. In this presentation, an analysis of these high-resolution observations focused on tropical trade cumuli is given. We will show that using the high-resolution Sentinel-2 observations, clouds and their shadows can be considered as individual objects with associated properties. A novel technique will be presented for deriving cloud height from Sentinel-2 observations, which exploits the geometric relationship between cloud objects and their shadows. Furthermore, the cloud fraction and cloud size distribution are calculated for various trade cumulus scenes. The uncertainties arising from decisions in our cloud and shadow detection scheme will be discussed.We show that a substantial fraction of clouds is unresolved at the spatial resolution of current meteorological satellite imagers. Consequently the cloud size distribution and domain-average cloud fraction from coarse resolution satellite imagers are shown to be biased and highly sensitive to pixel resolution. In addition, a large fraction of pixels identified as cloudy contains significant clear-sky contributions, and it is no longer possible to characterize clouds as objects. We will discuss how this affects the accuracy of cloud property determination and biases estimates of cloud radiative forcing., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)
Published: 2023
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18. Mortality and Recovery of Kidney Function in Kidney Replacement TherapyRequiring AKI: Data from All Affected In-Hospital Subjects

Author: Sturzebecher L, Ritter O, and Patschan D
Subjects: Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering
Abstract: Acute kidney injury (AKI) affects increasing numbers of hospitalized patients in Central Europe and in the US. Kidney replacement therapy (KRT) becomes mandatory if other strategies fail to prevent patients from systemic intoxication, resistant hyperhydration, or refractory hyperkalemia. The majority of data related to survival rates of AKI subjects that require KRT have been acquired under intensive care conditions. In the current letter to the editor we provide outcome data of all patients with in-hospital diagnosed AKI that received KRT at least once. We retrospectively assessed subjects receiving one or more individual sessions of KRT due to AKI of various etiology. Subjects were partly treated in the ICU or under non-ICU conditions. The in-hospital mortality was 35.4% complete recovery of kidney function occurred in 48.8%. In summary, the mortality of all inhospital AKI subjects is comparable to the mortality of AKI patients in the ICU. In addition, more than 50% do not recovery completely. Therefore, subjects with hospital-acquired AKI and an incident or prolonged need for KRT require the highest attention of nephrologists in general, no matter whether they received intensive care treatment or not.
Published: 2023
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19. Impact of renal impairment on atrial fibrillation

Author: Ding W. Y., Potpara T. S., Blomstrom-Lundqvist C., Boriani G., Marin F., Fauchier L., Lip G. Y. H., Tavazzi L., Maggioni A. P., Dan G. -A., Potpara T., Nabauer M., Kalarus Z., Goda A., Mairesse G., Shalganov T., Antoniades L., Taborsky M., Riahi S., Muda P., Garcia Bolao I., Piot O., Etsadashvili K., Simantirakis E., Haim M., Azhari A., Najafian J., Santini M., Mirrakhimov E., Kulzida K., Erglis A., Poposka L., Burg M., Crijns H., Erkuner O., Atar D., Lenarczyk R., Martins Oliveira M., Shah D., Serdechnaya E., Diker E., Lane D., Zera E., Ekmekciu U., Paparisto V., Tase M., Gjergo H., Dragoti J., Ciutea M., Ahadi N., Husseini Z. E., Raepers M., Leroy J., Haushan P., Jourdan A., Lepiece C., Desteghe L., Vijgen J., Koopman P., Van Genechten G., Heidbuchel H., Boussy T., De Coninck M., Van Eeckhoutte H., Bouckaert N., Friart A., Boreux J., Arend C., Evrard P., Stefan L., Hoffer E., Herzet J., Massoz M., Celentano C., Sprynger M., Pierard L., Melon P., Van Hauwaert B., Kuppens C., Faes D., Van Lier D., Van Dorpe A., Gerardy A., Deceuninck O., Xhaet O., Dormal F., Ballant E., Blommaert D., Yakova D., Hristov M., Yncheva T., Stancheva N., Tisheva S., Tokmakova M., Nikolov F., Gencheva D., Kunev B., Stoyanov M., Marchov D., Gelev V., Traykov V., Kisheva A., Tsvyatkov H., Shtereva R., Bakalska-Georgieva S., Slavcheva S., Yotov Y., Kubickova M., Marni Joensen A., Gammelmark A., Hvilsted Rasmussen L., Dinesen P., Krogh Veno S., Sorensen B., Korsgaard A., Andersen K., Fragtrup Hellum C., Svenningsen A., Nyvad O., Wiggers P., May O., Aarup A., Graversen B., Jensen L., Andersen M., Svejgaard M., Vester S., Hansen S., Lynggaard V., Ciudad M., Vettus R., Maestre A., Castano S., Cheggour S., Poulard J., Mouquet V., Leparree S., Bouet J., Taieb J., Doucy A., Duquenne H., Furber A., Dupuis J., Rautureau J., Font M., Damiano P., Lacrimini M., Abalea J., Boismal S., Menez T., Mansourati J., Range G., Gorka H., Laure C., Vassaliere C., Elbaz N., Lellouche N., Djouadi K., Roubille F., Dietz D., Davy J., Granier M., Winum P., Leperchois-Jacquey C., Kassim H., Marijon E., Le Heuzey J., Fedida J., Maupain C., Himbert C., Gandjbakhch E., Hidden-Lucet F., Duthoit G., Badenco N., Chastre T., Waintraub X., Oudihat M., Lacoste J., Stephan C., Bader H., Delarche N., Giry L., Arnaud D., Lopez C., Boury F., Brunello I., Lefevre M., Mingam R., Haissaguerre M., Le Bidan M., Pavin D., Le Moal V., Leclercq C., Beitar T., Martel I., Schmid A., Sadki N., Romeyer-Bouchard C., Da Costa A., Arnault I., Boyer M., Piat C., Lozance N., Nastevska S., Doneva A., Fortomaroska Milevska B., Sheshoski B., Petroska K., Taneska N., Bakrecheski N., Lazarovska K., Jovevska S., Ristovski V., Antovski A., Lazarova E., Kotlar I., Taleski J., Kedev S., Zlatanovik N., Jordanova S., Bajraktarova Proseva T., Doncovska S., Maisuradze D., Esakia A., Sagirashvili E., Lartsuliani K., Natelashvili N., Gumberidze N., Gvenetadze R., Gotonelia N., Kuridze N., Papiashvili G., Menabde I., Gloggler S., Napp A., Lebherz C., Romero H., Schmitz K., Berger M., Zink M., Koster S., Sachse J., Vonderhagen E., Soiron G., Mischke K., Reith R., Schneider M., Rieker W., Boscher D., Taschareck A., Beer A., Oster D., Ritter O., Adamczewski J., Walter S., Frommhold A., Luckner E., Richter J., Schellner M., Landgraf S., Bartholome S., Naumann R., Schoeler J., Westermeier D., William F., Wilhelm K., Maerkl M., Oekinghaus R., Denart M., Kriete M., Tebbe U., Scheibner T., Gruber M., Gerlach A., Beckendorf C., Anneken L., Arnold M., Lengerer S., Bal Z., Uecker C., Fortsch H., Fechner S., Mages V., Martens E., Methe H., Schmidt T., Schaeffer B., Hoffmann B., Moser J., Heitmann K., Willems S., Klaus C., Lange I., Durak M., Esen E., Mibach F., Mibach H., Utech A., Gabelmann M., Stumm R., Landle V., Gartner C., Goerg C., Kaul N., Messer S., Burkhardt D., Sander C., Orthen R., Kaes S., Baumer A., Dodos F., Barth A., Schaeffer G., Gaertner J., Winkler J., Fahrig A., Aring J., Wenzel I., Steiner S., Kliesch A., Kratz E., Winter K., Schneider P., Haag A., Mutscher I., Bosch R., Taggeselle J., Meixner S., Schnabel A., Shamalla A., Hotz H., Korinth A., Rheinert C., Mehltretter G., Schon B., Schon N., Starflinger A., Englmann E., Baytok G., Laschinger T., Ritscher G., Gerth A., Dechering D., Eckardt L., Kuhlmann M., Proskynitopoulos N., Brunn J., Foth K., Axthelm C., Hohensee H., Eberhard K., Turbanisch S., Hassler N., Koestler A., Stenzel G., Kschiwan D., Schwefer M., Neiner S., Hettwer S., Haeussler-Schuchardt M., Degenhardt R., Sennhenn S., Brendel M., Stoehr A., Widjaja W., Loehndorf S., Logemann A., Hoskamp J., Grundt J., Block M., Ulrych R., Reithmeier A., Panagopoulos V., Martignani C., Bernucci D., Fantecchi E., Diemberger I., Ziacchi M., Biffi M., Cimaglia P., Frisoni J., Giannini I., Boni S., Fumagalli S., Pupo S., Di Chiara A., Mirone P., Pesce F., Zoccali C., Malavasi V. L., Mussagaliyeva A., Ahyt B., Salihova Z., Koshum-Bayeva K., Kerimkulova A., Bairamukova A., Lurina B., Zuzans R., Jegere S., Mintale I., Kupics K., Jubele K., Kalejs O., Vanhear K., Cachia M., Abela E., Warwicker S., Tabone T., Xuereb R., Asanovic D., Drakalovic D., Vukmirovic M., Pavlovic N., Music L., Bulatovic N., Boskovic A., Uiterwaal H., Bijsterveld N., De Groot J., Neefs J., van den Berg N., Piersma F., Wilde A., Hagens V., Van Es J., van Opstal J., Van Rennes B., Verheij H., Breukers W., Tjeerdsma G., Nijmeijer R., Wegink D., Binnema R., Said S., Philippens S., van Doorn W., Szili-Torok T., Bhagwandien R., Janse P., Muskens A., van Eck M., Gevers R., van der Ven N., Duygun A., Rahel B., Meeder J., Vold A., Holst Hansen C., Engset I., Dyduch-Fejklowicz B., Koba E., Cichocka M., Sokal A., Kubicius A., Pruchniewicz E., Kowalik-Sztylc A., Czapla W., Mroz I., Kozlowski M., Pawlowski T., Tendera M., Winiarska-Filipek A., Fidyk A., Slowikowski A., Haberka M., Lachor-Broda M., Biedron M., Gasior Z., Kolodziej M., Janion M., Gorczyca-Michta I., Wozakowska-Kaplon B., Stasiak M., Jakubowski P., Ciurus T., Drozdz J., Simiera M., Zajac P., Wcislo T., Zycinski P., Kasprzak J., Olejnik A., Harc-Dyl E., Miarka J., Pasieka M., Zieminska-Luc M., Bujak W., Sliwinski A., Grech A., Morka J., Petrykowska K., Prasal M., Hordynski G., Feusette P., Lipski P., Wester A., Streb W., Romanek J., Wozniak P., Chlebus M., Szafarz P., Stanik W., Zakrzewski M., Kazmierczak J., Przybylska A., Skorek E., Blaszczyk H., Stepien M., Szabowski S., Krysiak W., Szymanska M., Karasinski J., Blicharz J., Skura M., Halas K., Michalczyk L., Orski Z., Krzyzanowski K., Skrobowski A., Zielinski L., Tomaszewska-Kiecana M., Dluzniewski M., Kiliszek M., Peller M., Budnik M., Balsam P., Opolski G., Tyminska A., Ozieranski K., Wancerz A., Borowiec A., Majos E., Dabrowski R., Szwed H., Musialik-Lydka A., Leopold-Jadczyk A., Jedrzejczyk-Patej E., Koziel M., Mazurek M., Krzemien-Wolska K., Starosta P., Nowalany-Kozielska E., Orzechowska A., Szpot M., Staszel M., Almeida S., Pereira H., Brandao Alves L., Miranda R., Ribeiro L., Costa F., Morgado F., Carmo P., Galvao Santos P., Bernardo R., Adragao P., Ferreira da Silva G., Peres M., Alves M., Leal M., Cordeiro A., Magalhaes P., Fontes P., Leao S., Delgado A., Costa A., Marmelo B., Rodrigues B., Moreira D., Santos J., Santos L., Terchet A., Darabantiu D., Mercea S., Turcin Halka V., Pop Moldovan A., Gabor A., Doka B., Catanescu G., Rus H., Oboroceanu L., Bobescu E., Popescu R., Dan A., Buzea A., Daha I., Dan G., Neuhoff I., Baluta M., Ploesteanu R., Dumitrache N., Vintila M., Daraban A., Japie C., Badila E., Tewelde H., Hostiuc M., Frunza S., Tintea E., Bartos D., Ciobanu A., Popescu I., Toma N., Gherghinescu C., Cretu D., Patrascu N., Stoicescu C., Udroiu C., Bicescu G., Vintila V., Vinereanu D., Cinteza M., Rimbas R., Grecu M., Cozma A., Boros F., Ille M., Tica O., Tor R., Corina A., Jeewooth A., Maria B., Georgiana C., Natalia C., Alin D., Dinu-Andrei D., Livia M., Daniela R., Larisa R., Umaar S., Tamara T., Ioachim Popescu M., Nistor D., Sus I., Coborosanu O., Alina-Ramona N., Dan R., Petrescu L., Ionescu G., Vacarescu C., Goanta E., Mangea M., Ionac A., Mornos C., Cozma D., Pescariu S., Solodovnicova E., Soldatova I., Shutova J., Tjuleneva L., Zubova T., Uskov V., Obukhov D., Rusanova G., Isakova N., Odinsova S., Arhipova T., Kazakevich E., Zavyalova O., Novikova T., Riabaia I., Zhigalov S., Drozdova E., Luchkina I., Monogarova Y., Hegya D., Rodionova L., Nevzorova V., Lusanova O., Arandjelovic A., Toncev D., Vukmirovic L., Radisavljevic M., Milanov M., Sekularac N., Zdravkovic M., Hinic S., Dimkovic S., Acimovic T., Saric J., Radovanovic S., Kocijancic A., Obrenovic-Kircanski B., Kalimanovska Ostric D., Simic D., Jovanovic I., Petrovic I., Polovina M., Vukicevic M., Tomasevic M., Mujovic N., Radivojevic N., Petrovic O., Aleksandric S., Kovacevic V., Mijatovic Z., Ivanovic B., Tesic M., Ristic A., Vujisic-Tesic B., Nedeljkovic M., Karadzic A., Uscumlic A., Prodanovic M., Zlatar M., Asanin M., Bisenic B., Vasic V., Popovic Z., Djikic D., Sipic M., Peric V., Dejanovic B., Milosevic N., Backovic S., Stevanovic A., Andric A., Pencic B., Pavlovic-Kleut M., Celic V., Pavlovic M., Petrovic M., Vuleta M., Petrovic N., Simovic S., Savovic Z., Milanov S., Davidovic G., Iric-Cupic V., Djordjevic D., Damjanovic M., Zdravkovic S., Topic V., Stanojevic D., Randjelovic M., Jankovic-Tomasevic R., Atanaskovic V., Antic S., Simonovic D., Stojanovic M., Stojanovic S., Mitic V., Ilic V., Petrovic D., Deljanin Ilic M., Ilic S., Stoickov V., Markovic S., Mijatovic A., Tanasic D., Radakovic G., Peranovic J., Panic-Jelic N., Vujadinovic O., Pajic P., Bekic S., Kovacevic S., Garcia Fernandez A., Perez Cabeza A., Anguita M., Tercedor Sanchez L., Mau E., Loayssa J., Ayarra M., Carpintero M., Roldan Rabadan I., Gil Ortega M., Tello Montoliu A., Orenes Pinero E., Manzano Fernandez S., Romero Aniorte A., Veliz Martinez A., Quintana Giner M., Ballesteros G., Palacio M., Alcalde O., Garcia-Bolao I., Bertomeu Gonzalez V., Otero-Ravina F., Garcia Seara J., Gonzalez Juanatey J., Dayal N., Maziarski P., Gentil-Baron P., Koc M., Onrat E., Dural I. E., Yilmaz K., Ozin B., Tan Kurklu S., Atmaca Y., Canpolat U., Tokgozoglu L., Dolu A. K., Demirtas B., Sahin D., Ozcan Celebi O., Gagirci G., Turk U. O., Ari H., Polat N., Toprak N., Sucu M., Akin Serdar O., Taha Alper A., Kepez A., Yuksel Y., Uzunselvi A., Yuksel S., Sahin M., Kayapinar O., Ozcan T., Kaya H., Yilmaz M. B., Kutlu M., Demir M., Gibbs C., Kaminskiene S., Bryce M., Skinner A., Belcher G., Hunt J., Stancombe L., Holbrook B., Peters C., Tettersell S., Shantsila A., Senoo K., Proietti M., Russell K., Domingos P., Hussain S., Partridge J., Haynes R., Bahadur S., Brown R., McMahon S., McDonald J., Balachandran K., Singh R., Garg S., Desai H., Davies K., Goddard W., Galasko G., Rahman I., Chua Y., Payne O., Preston S., Brennan O., Pedley L., Whiteside C., Dickinson C., Brown J., Jones K., Benham L., Brady R., Buchanan L., Ashton A., Crowther H., Fairlamb H., Thornthwaite S., Relph C., McSkeane A., Poultney U., Kelsall N., Rice P., Wilson T., Wrigley M., Kaba R., Patel T., Young E., Law J., Runnett C., Thomas H., McKie H., Fuller J., Pick S., Sharp A., Hunt A., Thorpe K., Hardman C., Cusack E., Adams L., Hough M., Keenan S., Bowring A., Watts J., Zaman J., Goffin K., Nutt H., Beerachee Y., Featherstone J., Mills C., Pearson J., Stephenson L., Grant S., Wilson A., Hawksworth C., Alam I., Robinson M., Ryan S., Egdell R., Gibson E., Holland M., Leonard D., Mishra B., Ahmad S., Randall H., Hill J., Reid L., George M., McKinley S., Brockway L., Milligan W., Sobolewska J., Muir J., Tuckis L., Winstanley L., Jacob P., Kaye S., Morby L., Jan A., Sewell T., Boos C., Wadams B., Cope C., Jefferey P., Andrews N., Getty A., Suttling A., Turner C., Hudson K., Austin R., Howe S., Iqbal R., Gandhi N., Brophy K., Mirza P., Willard E., Collins S., Ndlovu N., Subkovas E., Karthikeyan V., Waggett L., Wood A., Bolger A., Stockport J., Evans L., Harman E., Starling J., Williams L., Saul V., Sinha M., Bell L., Tudgay S., Kemp S., Frost L., Ingram T., Loughlin A., Adams C., Adams M., Hurford F., Owen C., Miller C., Donaldson D., Tivenan H., Button H., Nasser A., Jhagra O., Stidolph B., Brown C., Livingstone C., Duffy M., Madgwick P., Roberts P., Greenwood E., Fletcher L., Beveridge M., Earles S., McKenzie D., Beacock D., Dayer M., Seddon M., Greenwell D., Luxton F., Venn F., Mills H., Rewbury J., James K., Roberts K., Tonks L., Felmeden D., Taggu W., Summerhayes A., Hughes D., Sutton J., Felmeden L., Khan M., Walker E., Norris L., O'Donohoe L., Mozid A., Dymond H., Lloyd-Jones H., Saunders G., Simmons D., Coles D., Cotterill D., Beech S., Kidd S., Wrigley B., Petkar S., Smallwood A., Jones R., Radford E., Milgate S., Metherell S., Cottam V., Buckley C., Broadley A., Wood D., Allison J., Rennie K., Balian L., Howard L., Pippard L., Board S., Pitt-Kerby T., UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Ding W.Y., Potpara T.S., Blomstrom-Lundqvist C., Boriani G., Marin F., Fauchier L., Lip G.Y.H., Tavazzi L., Maggioni A.P., Dan G.-A., Potpara T., Nabauer M., Kalarus Z., Goda A., Mairesse G., Shalganov T., Antoniades L., Taborsky M., Riahi S., Muda P., Garcia Bolao I., Piot O., Etsadashvili K., Simantirakis E., Haim M., Azhari A., Najafian J., Santini M., Mirrakhimov E., Kulzida K., Erglis A., Poposka L., Burg M., Crijns H., Erkuner O., Atar D., Lenarczyk R., Martins Oliveira M., Shah D., Serdechnaya E., Diker E., Lane D., Zera E., Ekmekciu U., Paparisto V., Tase M., Gjergo H., Dragoti J., Ciutea M., Ahadi N., Husseini Z.E., Raepers M., Leroy J., Haushan P., Jourdan A., Lepiece C., Desteghe L., Vijgen J., Koopman P., Van Genechten G., Heidbuchel H., Boussy T., De Coninck M., Van Eeckhoutte H., Bouckaert N., Friart A., Boreux J., Arend C., Evrard P., Stefan L., Hoffer E., Herzet J., Massoz M., Celentano C., Sprynger M., Pierard L., Melon P., Van Hauwaert B., Kuppens C., Faes D., Van Lier D., Van Dorpe A., Gerardy A., Deceuninck O., Xhaet O., Dormal F., Ballant E., Blommaert D., Yakova D., Hristov M., Yncheva T., Stancheva N., Tisheva S., Tokmakova M., Nikolov F., Gencheva D., Kunev B., Stoyanov M., Marchov D., Gelev V., Traykov V., Kisheva A., Tsvyatkov H., Shtereva R., Bakalska-Georgieva S., Slavcheva S., Yotov Y., Kubickova M., Marni Joensen A., Gammelmark A., Hvilsted Rasmussen L., Dinesen P., Krogh Veno S., Sorensen B., Korsgaard A., Andersen K., Fragtrup Hellum C., Svenningsen A., Nyvad O., Wiggers P., May O., Aarup A., Graversen B., Jensen L., Andersen M., Svejgaard M., Vester S., Hansen S., Lynggaard V., Ciudad M., Vettus R., Maestre A., Castano S., Cheggour S., Poulard J., Mouquet V., Leparree S., Bouet J., Taieb J., Doucy A., Duquenne H., Furber A., Dupuis J., Rautureau J., Font M., Damiano P., Lacrimini M., Abalea J., Boismal S., Menez T., Mansourati J., Range G., Gorka H., Laure C., Vassaliere C., Elbaz N., Lellouche N., Djouadi K., Roubille F., Dietz D., Davy J., Granier M., Winum P., Leperchois-Jacquey C., Kassim H., Marijon E., Le Heuzey J., Fedida J., Maupain C., Himbert C., Gandjbakhch E., Hidden-Lucet F., Duthoit G., Badenco N., Chastre T., Waintraub X., Oudihat M., Lacoste J., Stephan C., Bader H., Delarche N., Giry L., Arnaud D., Lopez C., Boury F., Brunello I., Lefevre M., Mingam R., Haissaguerre M., Le Bidan M., Pavin D., Le Moal V., Leclercq C., Beitar T., Martel I., Schmid A., Sadki N., Romeyer-Bouchard C., Da Costa A., Arnault I., Boyer M., Piat C., Lozance N., Nastevska S., Doneva A., Fortomaroska Milevska B., Sheshoski B., Petroska K., Taneska N., Bakrecheski N., Lazarovska K., Jovevska S., Ristovski V., Antovski A., Lazarova E., Kotlar I., Taleski J., Kedev S., Zlatanovik N., Jordanova S., Bajraktarova Proseva T., Doncovska S., Maisuradze D., Esakia A., Sagirashvili E., Lartsuliani K., Natelashvili N., Gumberidze N., Gvenetadze R., Gotonelia N., Kuridze N., Papiashvili G., Menabde I., Gloggler S., Napp A., Lebherz C., Romero H., Schmitz K., Berger M., Zink M., Koster S., Sachse J., Vonderhagen E., Soiron G., Mischke K., Reith R., Schneider M., Rieker W., Boscher D., Taschareck A., Beer A., Oster D., Ritter O., Adamczewski J., Walter S., Frommhold A., Luckner E., Richter J., Schellner M., Landgraf S., Bartholome S., Naumann R., Schoeler J., Westermeier D., William F., Wilhelm K., Maerkl M., Oekinghaus R., Denart M., Kriete M., Tebbe U., Scheibner T., Gruber M., Gerlach A., Beckendorf C., Anneken L., Arnold M., Lengerer S., Bal Z., Uecker C., Fortsch H., Fechner S., Mages V., Martens E., Methe H., Schmidt T., Schaeffer B., Hoffmann B., Moser J., Heitmann K., Willems S., Klaus C., Lange I., Durak M., Esen E., Mibach F., Mibach H., Utech A., Gabelmann M., Stumm R., Landle V., Gartner C., Goerg C., Kaul N., Messer S., Burkhardt D., Sander C., Orthen R., Kaes S., Baumer A., Dodos F., Barth A., Schaeffer G., Gaertner J., Winkler J., Fahrig A., Aring J., Wenzel I., Steiner S., Kliesch A., Kratz E., Winter K., Schneider P., Haag A., Mutscher I., Bosch R., Taggeselle J., Meixner S., Schnabel A., Shamalla A., Hotz H., Korinth A., Rheinert C., Mehltretter G., Schon B., Schon N., Starflinger A., Englmann E., Baytok G., Laschinger T., Ritscher G., Gerth A., Dechering D., Eckardt L., Kuhlmann M., Proskynitopoulos N., Brunn J., Foth K., Axthelm C., Hohensee H., Eberhard K., Turbanisch S., Hassler N., Koestler A., Stenzel G., Kschiwan D., Schwefer M., Neiner S., Hettwer S., Haeussler-Schuchardt M., Degenhardt R., Sennhenn S., Brendel M., Stoehr A., Widjaja W., Loehndorf S., Logemann A., Hoskamp J., Grundt J., Block M., Ulrych R., Reithmeier A., Panagopoulos V., Martignani C., Bernucci D., Fantecchi E., Diemberger I., Ziacchi M., Biffi M., Cimaglia P., Frisoni J., Giannini I., Boni S., Fumagalli S., Pupo S., Di Chiara A., Mirone P., Pesce F., Zoccali C., Malavasi V.L., Mussagaliyeva A., Ahyt B., Salihova Z., Koshum-Bayeva K., Kerimkulova A., Bairamukova A., Lurina B., Zuzans R., Jegere S., Mintale I., Kupics K., Jubele K., Kalejs O., Vanhear K., Cachia M., Abela E., Warwicker S., Tabone T., Xuereb R., Asanovic D., Drakalovic D., Vukmirovic M., Pavlovic N., Music L., Bulatovic N., Boskovic A., Uiterwaal H., Bijsterveld N., De Groot J., Neefs J., van den Berg N., Piersma F., Wilde A., Hagens V., Van Es J., van Opstal J., Van Rennes B., Verheij H., Breukers W., Tjeerdsma G., Nijmeijer R., Wegink D., Binnema R., Said S., Philippens S., van Doorn W., Szili-Torok T., Bhagwandien R., Janse P., Muskens A., van Eck M., Gevers R., van der Ven N., Duygun A., Rahel B., Meeder J., Vold A., Holst Hansen C., Engset I., Dyduch-Fejklowicz B., Koba E., Cichocka M., Sokal A., Kubicius A., Pruchniewicz E., Kowalik-Sztylc A., Czapla W., Mroz I., Kozlowski M., Pawlowski T., Tendera M., Winiarska-Filipek A., Fidyk A., Slowikowski A., Haberka M., Lachor-Broda M., Biedron M., Gasior Z., Kolodziej M., Janion M., Gorczyca-Michta I., Wozakowska-Kaplon B., Stasiak M., Jakubowski P., Ciurus T., Drozdz J., Simiera M., Zajac P., Wcislo T., Zycinski P., Kasprzak J., Olejnik A., Harc-Dyl E., Miarka J., Pasieka M., Zieminska-Luc M., Bujak W., Sliwinski A., Grech A., Morka J., Petrykowska K., Prasal M., Hordynski G., Feusette P., Lipski P., Wester A., Streb W., Romanek J., Wozniak P., Chlebus M., Szafarz P., Stanik W., Zakrzewski M., Kazmierczak J., Przybylska A., Skorek E., Blaszczyk H., Stepien M., Szabowski S., Krysiak W., Szymanska M., Karasinski J., Blicharz J., Skura M., Halas K., Michalczyk L., Orski Z., Krzyzanowski K., Skrobowski A., Zielinski L., Tomaszewska-Kiecana M., Dluzniewski M., Kiliszek M., Peller M., Budnik M., Balsam P., Opolski G., Tyminska A., Ozieranski K., Wancerz A., Borowiec A., Majos E., Dabrowski R., Szwed H., Musialik-Lydka A., Leopold-Jadczyk A., Jedrzejczyk-Patej E., Koziel M., Mazurek M., Krzemien-Wolska K., Starosta P., Nowalany-Kozielska E., Orzechowska A., Szpot M., Staszel M., Almeida S., Pereira H., Brandao Alves L., Miranda R., Ribeiro L., Costa F., Morgado F., Carmo P., Galvao Santos P., Bernardo R., Adragao P., Ferreira da Silva G., Peres M., Alves M., Leal M., Cordeiro A., Magalhaes P., Fontes P., Leao S., Delgado A., Costa A., Marmelo B., Rodrigues B., Moreira D., Santos J., Santos L., Terchet A., Darabantiu D., Mercea S., Turcin Halka V., Pop Moldovan A., Gabor A., Doka B., Catanescu G., Rus H., Oboroceanu L., Bobescu E., Popescu R., Dan A., Buzea A., Daha I., Dan G., Neuhoff I., Baluta M., Ploesteanu R., Dumitrache N., Vintila M., Daraban A., Japie C., Badila E., Tewelde H., Hostiuc M., Frunza S., Tintea E., Bartos D., Ciobanu A., Popescu I., Toma N., Gherghinescu C., Cretu D., Patrascu N., Stoicescu C., Udroiu C., Bicescu G., Vintila V., Vinereanu D., Cinteza M., Rimbas R., Grecu M., Cozma A., Boros F., Ille M., Tica O., Tor R., Corina A., Jeewooth A., Maria B., Georgiana C., Natalia C., Alin D., Dinu-Andrei D., Livia M., Daniela R., Larisa R., Umaar S., Tamara T., Ioachim Popescu M., Nistor D., Sus I., Coborosanu O., Alina-Ramona N., Dan R., Petrescu L., Ionescu G., Vacarescu C., Goanta E., Mangea M., Ionac A., Mornos C., Cozma D., Pescariu S., Solodovnicova E., Soldatova I., Shutova J., Tjuleneva L., Zubova T., Uskov V., Obukhov D., Rusanova G., Isakova N., Odinsova S., Arhipova T., Kazakevich E., Zavyalova O., Novikova T., Riabaia I., Zhigalov S., Drozdova E., Luchkina I., Monogarova Y., Hegya D., Rodionova L., Nevzorova V., Lusanova O., Arandjelovic A., Toncev D., Vukmirovic L., Radisavljevic M., Milanov M., Sekularac N., Zdravkovic M., Hinic S., Dimkovic S., Acimovic T., Saric J., Radovanovic S., Kocijancic A., Obrenovic-Kircanski B., Kalimanovska Ostric D., Simic D., Jovanovic I., Petrovic I., Polovina M., Vukicevic M., Tomasevic M., Mujovic N., Radivojevic N., Petrovic O., Aleksandric S., Kovacevic V., Mijatovic Z., Ivanovic B., Tesic M., Ristic A., Vujisic-Tesic B., Nedeljkovic M., Karadzic A., Uscumlic A., Prodanovic M., Zlatar M., Asanin M., Bisenic B., Vasic V., Popovic Z., Djikic D., Sipic M., Peric V., Dejanovic B., Milosevic N., Backovic S., Stevanovic A., Andric A., Pencic B., Pavlovic-Kleut M., Celic V., Pavlovic M., Petrovic M., Vuleta M., Petrovic N., Simovic S., Savovic Z., Milanov S., Davidovic G., Iric-Cupic V., Djordjevic D., Damjanovic M., Zdravkovic S., Topic V., Stanojevic D., Randjelovic M., Jankovic-Tomasevic R., Atanaskovic V., Antic S., Simonovic D., Stojanovic M., Stojanovic S., Mitic V., Ilic V., Petrovic D., Deljanin Ilic M., Ilic S., Stoickov V., Markovic S., Mijatovic A., Tanasic D., Radakovic G., Peranovic J., Panic-Jelic N., Vujadinovic O., Pajic P., Bekic S., Kovacevic S., Garcia Fernandez A., Perez Cabeza A., Anguita M., Tercedor Sanchez L., Mau E., Loayssa J., Ayarra M., Carpintero M., Roldan Rabadan I., Gil Ortega M., Tello Montoliu A., Orenes Pinero E., Manzano Fernandez S., Romero Aniorte A., Veliz Martinez A., Quintana Giner M., Ballesteros G., Palacio M., Alcalde O., Garcia-Bolao I., Bertomeu Gonzalez V., Otero-Ravina F., Garcia Seara J., Gonzalez Juanatey J., Dayal N., Maziarski P., Gentil-Baron P., Koc M., Onrat E., Dural I.E., Yilmaz K., Ozin B., Tan Kurklu S., Atmaca Y., Canpolat U., Tokgozoglu L., Dolu A.K., Demirtas B., Sahin D., Ozcan Celebi O., Gagirci G., Turk U.O., Ari H., Polat N., Toprak N., Sucu M., Akin Serdar O., Taha Alper A., Kepez A., Yuksel Y., Uzunselvi A., Yuksel S., Sahin M., Kayapinar O., Ozcan 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Hawksworth C., Alam I., Robinson M., Ryan S., Egdell R., Gibson E., Holland M., Leonard D., Mishra B., Ahmad S., Randall H., Hill J., Reid L., George M., McKinley S., Brockway L., Milligan W., Sobolewska J., Muir J., Tuckis L., Winstanley L., Jacob P., Kaye S., Morby L., Jan A., Sewell T., Boos C., Wadams B., Cope C., Jefferey P., Andrews N., Getty A., Suttling A., Turner C., Hudson K., Austin R., Howe S., Iqbal R., Gandhi N., Brophy K., Mirza P., Willard E., Collins S., Ndlovu N., Subkovas E., Karthikeyan V., Waggett L., Wood A., Bolger A., Stockport J., Evans L., Harman E., Starling J., Williams L., Saul V., Sinha M., Bell L., Tudgay S., Kemp S., Frost L., Ingram T., Loughlin A., Adams C., Adams M., Hurford F., Owen C., Miller C., Donaldson D., Tivenan H., Button H., Nasser A., Jhagra O., Stidolph B., Brown C., Livingstone C., Duffy M., Madgwick P., Roberts P., Greenwood E., Fletcher L., Beveridge M., Earles S., McKenzie D., Beacock D., Dayer M., Seddon M., Greenwell D., Luxton F., Venn F., Mills H., Rewbury J., James K., Roberts K., Tonks L., Felmeden D., Taggu W., Summerhayes A., Hughes D., Sutton J., Felmeden L., Khan M., Walker E., Norris L., O'Donohoe L., Mozid A., Dymond H., Lloyd-Jones H., Saunders G., Simmons D., Coles D., Cotterill D., Beech S., Kidd S., Wrigley B., Petkar S., Smallwood A., Jones R., Radford E., Milgate S., Metherell S., Cottam V., Buckley C., Broadley A., Wood D., Allison J., Rennie K., Balian L., Howard L., Pippard L., Board S., Pitt-Kerby T., Pulmonary medicine, Rehabilitation medicine, Internal medicine, and Radiology and nuclear medicine
Subjects: Male, Medicin och hälsovetenskap, Clinical Biochemistry, Hemorrhage, Medical and Health Sciences, Biochemistry, Brain Ischemia, Risk Factors, Hemorrhage/chemically induced, death, Humans, Acute Coronary Syndrome/complications, atrial fibrillation, Renal Insufficiency, Registries, Acute Coronary Syndrome, Renal Insufficiency/chemically induced, Anticoagulants, General Medicine, thromboembolism, kidney failure, Stroke, Anticoagulants/therapeutic use, major bleeding, outcome, Female, Atrial Fibrillation/complications, chronic kidney disease, Stroke/complications
Abstract: Background: Atrial fibrillation (AF) and renal impairment share a bidirectional relationship with important pathophysiological interactions. We evaluated the impact of renal impairment in a contemporary cohort of patients with AF. Methods: We utilised the ESC-EHRA EORP-AF Long-Term General Registry. Outcomes were analysed according to renal function by CKD-EPI equation. The primary endpoint was a composite of thromboembolism, major bleeding, acute coronary syndrome and all-cause death. Secondary endpoints were each of these separately including ischaemic stroke, haemorrhagic event, intracranial haemorrhage, cardiovascular death and hospital admission. Results: A total of 9306 patients were included. The distribution of patients with no, mild, moderate and severe renal impairment at baseline were 16.9%, 49.3%, 30% and 3.8%, respectively. AF patients with impaired renal function were older, more likely to be females, had worse cardiac imaging parameters and multiple comorbidities. Among patients with an indication for anticoagulation, prescription of these agents was reduced in those with severe renal impairment, p 2 decrease), that was most notable in patients with eGFR 2 (HR 2.21 [95% CI, 1.23–3.99] compared to eGFR ≥90 ml/min/1.73 m 2). Conclusion: A significant proportion of patients with AF suffer from concomitant renal impairment which impacts their overall management. Furthermore, renal impairment is an independent predictor of major adverse events including thromboembolism, major bleeding, acute coronary syndrome and all-cause death in patients with AF.
Published: 2022
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20. Reduced antioxiadant high-density lipoprotein function in patients with acute coronary syndrome

Author: Pagonas, N, primary, Weiland, L, additional, Jaensch, M, additional, Dammernmann, W, additional, Christ, M, additional, Ritter, O, additional, Westhoff, T, additional, Kelesidis, T, additional, and Sasko, B, additional
Published: 2022
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21. Association of propionate with coronary artery disease in a large cross-sectional study

Author: Pagonas, N, primary, Sasko, B, additional, Seibert, F, additional, Ritter, O, additional, Babel, N, additional, and Westhoff, T, additional
Published: 2022
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22. Description of a novel RyR2 mutation in a juvenile patient with symptomatic catecholaminergic polymorphic ventricular tachycardia in sleep and during exercise: a case report

Author: Seidlmayer, L. K., Riediger, F., Pagonas, N., Nordbeck, P., Ritter, O., and Sasko, B.
Published: 2018
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23. Epidemiology and impact of frailty in patients with atrial fibrillation in Europe

Author: Proietti, Marco, Romiti, Giulio Francesco, Vitolo, Marco, Harrison, Stephanie L., Lane, Deirdre A., Fauchier, Laurent, Marin, Francisco, Näbauer, Michael, Potpara, Tatjana S., Dan, Gheorghe-Andrei, Maggioni, Aldo P., Cesari, Matteo, Boriani, Giuseppe, Lip, Gregory Y. 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Subjects: Oral, Male, Aging, Administration, Oral, frailty, Frailty/chemically induced, outcomes, Europe/epidemiology, older people, Risk Factors, atrial fibrillation, chronicity, epidemiology, oral anticoagulant therapy, Aged, Anticoagulants, Europe, Female, Humans, Quality of Life, Registries, Atrial Fibrillation, Frailty, Stroke, Atrial Fibrillation/diagnosis, General Medicine, Administration, Geriatrics and Gerontology, Anticoagulants/adverse effects, Stroke/complications
Abstract: Background Frailty is a medical syndrome characterised by reduced physiological reserve and increased vulnerability to stressors. Data regarding the relationship between frailty and atrial fibrillation (AF) are still inconsistent. Objectives We aim to perform a comprehensive evaluation of frailty in a large European cohort of AF patients. Methods A 40-item frailty index (FI) was built according to the accumulation of deficits model in the AF patients enrolled in the ESC-EHRA EORP-AF General Long-Term Registry. Association of baseline characteristics, clinical management, quality of life, healthcare resources use and risk of outcomes with frailty was examined. Results Among 10,177 patients [mean age (standard deviation) 69.0 (11.4) years, 4,103 (40.3%) females], 6,066 (59.6%) were pre-frail and 2,172 (21.3%) were frail, whereas only 1,939 (19.1%) were considered robust. Baseline thromboembolic and bleeding risks were independently associated with increasing FI. Frail patients with AF were less likely to be treated with oral anticoagulants (OACs) (odds ratio 0.70, 95% confidence interval 0.55–0.89), especially with non-vitamin K antagonist OACs and managed with a rhythm control strategy, compared with robust patients. Increasing frailty was associated with a higher risk for all outcomes examined, with a non-linear exponential relationship. The use of OAC was associated with a lower risk of outcomes, except in patients with very/extremely high frailty. Conclusions In this large cohort of AF patients, there was a high burden of frailty, influencing clinical management and risk of adverse outcomes. The clinical benefit of OAC is maintained in patients with high frailty, but not in very high/extremely frail ones.
Published: 2022
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24. Impact of diabetes on the management and outcomes in atrial fibrillation: an analysis from the ESC-EHRA EORP-AF Long-Term General Registry

Author: Ding, Wern Yew, primary, Kotalczyk, Agnieszka, additional, Boriani, Giuseppe, additional, Marin, Francisco, additional, Blomström-Lundqvist, Carina, additional, Potpara, Tatjana S., additional, Fauchier, Laurent, additional, Lip, Gregory.Y.H., additional, Boriani, G., additional, Lip, G.Y.H., additional, Tavazzi, L., additional, Maggioni, A.P., additional, Dan, G.-A., additional, Potpara, T., additional, Nabauer, M., additional, Marin, F., additional, Kalarus, Z., additional, Goda, A., additional, Mairesse, G., additional, Shalganov, T., additional, Antoniades, L., additional, Taborsky, M., additional, Riahi, S., additional, Muda, P., additional, García Bolao, I., additional, Piot, O., additional, Etsadashvili, K., additional, Simantirakis, E., additional, Haim, M., additional, Azhari, A., additional, Najafian, J., additional, Santini, M., additional, Mirrakhimov, E., additional, Kulzida, K.A., additional, Erglis, A., additional, Poposka, L., additional, Burg, M., additional, Crijns, H., additional, Erküner, Ö., additional, Atar, D., additional, Lenarczyk, R., additional, Martins Oliveira, M., additional, Shah, D., additional, Serdechnaya, E., additional, Diker, E., additional, Lane, D., additional, Zëra, E., additional, Ekmekçiu, U., additional, Paparisto, V., additional, Tase, M., additional, Gjergo, H., additional, Dragoti, J., additional, Ciutea, M., additional, Ahadi, N., additional, el Husseini, Z., additional, Raepers, M., additional, Leroy, J., additional, Haushan, P., additional, Jourdan, A., additional, Lepiece, C., additional, Desteghe, L., additional, Vijgen, J., additional, Koopman, P., additional, Van Genechten, G., additional, Heidbuchel, H., additional, Boussy, T., additional, De Coninck, M., additional, Van Eeckhoutte, H., additional, Bouckaert, N., additional, Friart, A., additional, Boreux, J., additional, Arend, C., additional, Evrard, P., additional, Stefan, L., additional, Hoffer, E., additional, Herzet, J., additional, Massoz, M., additional, Celentano, C., additional, Sprynger, M., additional, Pierard, L., additional, Melon, P., additional, Van Hauwaert, B., additional, Kuppens, C., additional, Faes, D., additional, Van Lier, D., additional, Van Dorpe, A., additional, Gerardy, A., additional, Deceuninck, O., additional, Xhaet, O., additional, Dormal, F., additional, Ballant, E., additional, Blommaert, D., additional, Yakova, D., additional, Hristov, M., additional, Yncheva, T., additional, Stancheva, N., additional, Tisheva, S., additional, Tokmakova, M., additional, Nikolov, F., additional, Gencheva, D., additional, Kunev, B., additional, Stoyanov, M., additional, Marchov, D., additional, Gelev, V., additional, Traykov, V., additional, Kisheva, A., additional, Tsvyatkov, H., additional, Shtereva, R., additional, Bakalska-Georgieva, S., additional, Slavcheva, S., additional, Yotov, Y., additional, Kubíčková, M., additional, Marni Joensen, A., additional, Gammelmark, A., additional, Hvilsted Rasmussen, L., 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Kazakevich, E., additional, Zavyalova, O., additional, Novikova, T., additional, Riabaia, I., additional, Zhigalov, S., additional, Drozdova, E., additional, Luchkina, I., additional, Monogarova, Y., additional, Hegya, D., additional, Rodionova, L., additional, Nevzorova, V., additional, Lusanova, O., additional, Arandjelovic, A., additional, Toncev, D., additional, Vukmirovic, L., additional, Radisavljevic, M., additional, Milanov, M., additional, Sekularac, N., additional, Zdravkovic, M., additional, Hinic, S., additional, Dimkovic, S., additional, Acimovic, T., additional, Saric, J., additional, Radovanovic, S., additional, Kocijancic, A., additional, Obrenovic-Kircanski, B., additional, Kalimanovska Ostric, D., additional, Simic, D., additional, Jovanovic, I., additional, Petrovic, I., additional, Polovina, M., additional, Vukicevic, M., additional, Tomasevic, M., additional, Mujovic, N., additional, Radivojevic, N., additional, Petrovic, O., additional, Aleksandric, S., additional, Kovacevic, V., additional, Mijatovic, Z., additional, Ivanovic, B., additional, Tesic, M., additional, Ristic, A., additional, Vujisic-Tesic, B., additional, Nedeljkovic, M., additional, Karadzic, A., additional, Uscumlic, A., additional, Prodanovic, M., additional, Zlatar, M., additional, Asanin, M., additional, Bisenic, B., additional, Vasic, V., additional, Popovic, Z., additional, Djikic, D., additional, Sipic, M., additional, Peric, V., additional, Dejanovic, B., additional, Milosevic, N., additional, Backovic, S., additional, Stevanovic, A., additional, Andric, A., additional, Pencic, B., additional, Pavlovic-Kleut, M., additional, Celic, V., additional, Pavlovic, M., additional, Petrovic, M., additional, Vuleta, M., additional, Petrovic, N., additional, Simovic, S., additional, Savovic, Z., additional, Milanov, S., additional, Davidovic, G., additional, Iric-Cupic, V., additional, Djordjevic, D., additional, Damjanovic, M., additional, Zdravkovic, S., additional, Topic, V., additional, Stanojevic, D., additional, Randjelovic, M., additional, Jankovic-Tomasevic, R., additional, Atanaskovic, V., additional, Antic, S., additional, Simonovic, D., additional, Stojanovic, M., additional, Stojanovic, S., additional, Mitic, V., additional, Ilic, V., additional, Petrovic, D., additional, Deljanin Ilic, M., additional, Ilic, S., additional, Stoickov, V., additional, Markovic, S., additional, Mijatovic, A., additional, Tanasic, D., additional, Radakovic, G., additional, Peranovic, J., additional, Panic-Jelic, N., additional, Vujadinovic, O., additional, Pajic, P., additional, Bekic, S., additional, Kovacevic, S., additional, García Fernandez, A., additional, Perez Cabeza, A., additional, Anguita, M., additional, Tercedor Sanchez, L., additional, Mau, E., additional, Loayssa, J., additional, Ayarra, M., additional, Carpintero, M., additional, Roldán Rabadan, I., additional, Gil Ortega, M., additional, Tello Montoliu, A., additional, Orenes Piñero, E., additional, Manzano Fernández, S., additional, Marín, F., additional, Romero Aniorte, A., additional, Veliz Martínez, A., additional, Quintana Giner, M., additional, Ballesteros, G., additional, Palacio, M., additional, Alcalde, O., additional, García-Bolao, I., additional, Bertomeu Gonzalez, V., additional, Otero-Raviña, F., additional, García Seara, J., additional, Gonzalez Juanatey, J., additional, Dayal, N., additional, Maziarski, P., additional, Gentil-Baron, P., additional, Koç, M., additional, Onrat, E., additional, Dural, I.E., additional, Yilmaz, K., additional, Özin, B., additional, Tan Kurklu, S., additional, Atmaca, Y., additional, Canpolat, U., additional, Tokgozoglu, L., additional, Dolu, A.K., additional, Demirtas, B., additional, Sahin, D., additional, Ozcan Celebi, O., additional, Gagirci, G., additional, Turk, U.O., additional, Ari, H., additional, Polat, N., additional, Toprak, N., additional, Sucu, M., additional, Akin Serdar, O., additional, Taha Alper, A., additional, Kepez, A., additional, Yuksel, Y., additional, Uzunselvi, A., additional, Yuksel, S., additional, Sahin, M., additional, Kayapinar, O., additional, Ozcan, T., additional, Kaya, H., additional, Yilmaz, M.B., additional, Kutlu, M., additional, Demir, M., additional, Gibbs, C., additional, Kaminskiene, S., additional, Bryce, M., additional, Skinner, A., additional, Belcher, G., additional, Hunt, J., additional, Stancombe, L., additional, Holbrook, B., additional, Peters, C., additional, Tettersell, S., additional, Shantsila, A., additional, Senoo, K., additional, Proietti, M., additional, Russell, K., additional, Domingos, P., additional, Hussain, S., additional, Partridge, J., additional, Haynes, R., additional, Bahadur, S., additional, Brown, R., additional, McMahon, S., additional, McDonald, J., additional, Balachandran, K., additional, Singh, R., additional, Garg, S., additional, Desai, H., additional, Davies, K., additional, Goddard, W., additional, Galasko, G., additional, Rahman, I., additional, Chua, Y., additional, Payne, O., additional, Preston, S., additional, Brennan, O., additional, Pedley, L., additional, Whiteside, C., additional, Dickinson, C., additional, Brown, J., additional, Jones, K., additional, Benham, L., additional, Brady, R., additional, Buchanan, L., additional, Ashton, A., additional, Crowther, H., additional, Fairlamb, H., additional, Thornthwaite, S., additional, Relph, C., additional, McSkeane, A., additional, Poultney, U., additional, Kelsall, N., additional, Rice, P., additional, Wilson, T., additional, Wrigley, M., additional, Kaba, R., additional, Patel, T., additional, Young, E., additional, Law, J., additional, Runnett, C., additional, Thomas, H., additional, McKie, H., additional, Fuller, J., additional, Pick, S., additional, Sharp, A., additional, Hunt, A., additional, Thorpe, K., additional, Hardman, C., additional, Cusack, E., additional, Adams, L., additional, Hough, M., additional, Keenan, S., additional, Bowring, A., additional, Watts, J., additional, Zaman, J., additional, Goffin, K., additional, Nutt, H., additional, Beerachee, Y., additional, Featherstone, J., additional, Mills, C., additional, Pearson, J., additional, Stephenson, L., additional, Grant, S., additional, Wilson, A., additional, Hawksworth, C., additional, Alam, I., additional, Robinson, M., additional, Ryan, S., additional, Egdell, R., additional, Gibson, E., additional, Holland, M., additional, Leonard, D., additional, Mishra, B., additional, Ahmad, S., additional, Randall, H., additional, Hill, J., additional, Reid, L., additional, George, M., additional, McKinley, S., additional, Brockway, L., additional, Milligan, W., additional, Sobolewska, J., additional, Muir, J., additional, Tuckis, L., additional, Winstanley, L., additional, Jacob, P., additional, Kaye, S., additional, Morby, L., additional, Jan, A., additional, Sewell, T., additional, Boos, C., additional, Wadams, B., additional, Cope, C., additional, Jefferey, P., additional, Andrews, N., additional, Getty, A., additional, Suttling, A., additional, Turner, C., additional, Hudson, K., additional, Austin, R., additional, Howe, S., additional, Iqbal, R., additional, Gandhi, N., additional, Brophy, K., additional, Mirza, P., additional, Willard, E., additional, Collins, S., additional, Ndlovu, N., additional, Subkovas, E., additional, Karthikeyan, V., additional, Waggett, L., additional, Wood, A., additional, Bolger, A., additional, Stockport, J., additional, Evans, L., additional, Harman, E., additional, Starling, J., additional, Williams, L., additional, Saul, V., additional, Sinha, M., additional, Bell, L., additional, Tudgay, S., additional, Kemp, S., additional, Frost, L., additional, Ingram, T., additional, Loughlin, A., additional, Adams, C., additional, Adams, M., additional, Hurford, F., additional, Owen, C., additional, Miller, C., additional, Donaldson, D., additional, Tivenan, H., additional, Button, H., additional, Nasser, A., additional, Jhagra, O., additional, Stidolph, B., additional, Brown, C., additional, Livingstone, C., additional, Duffy, M., additional, Madgwick, P., additional, Roberts, P., additional, Greenwood, E., additional, Fletcher, L., additional, Beveridge, M., additional, Earles, S., additional, McKenzie, D., additional, Beacock, D., additional, Dayer, M., additional, Seddon, M., additional, Greenwell, D., additional, Luxton, F., additional, Venn, F., additional, Mills, H., additional, Rewbury, J., additional, James, K., additional, Roberts, K., additional, Tonks, L., additional, Felmeden, D., additional, Taggu, W., additional, Summerhayes, A., additional, Hughes, D., additional, Sutton, J., additional, Felmeden, L., additional, Khan, M., additional, Walker, E., additional, Norris, L., additional, O'Donohoe, L., additional, Mozid, A., additional, Dymond, H., additional, Lloyd-Jones, H., additional, Saunders, G., additional, Simmons, D., additional, Coles, D., additional, Cotterill, D., additional, Beech, S., additional, Kidd, S., additional, Wrigley, B., additional, Petkar, S., additional, Smallwood, A., additional, Jones, R., additional, Radford, E., additional, Milgate, S., additional, Metherell, S., additional, Cottam, V., additional, Buckley, C., additional, Broadley, A., additional, Wood, D., additional, Allison, J., additional, Rennie, K., additional, Balian, L., additional, Howard, L., additional, Pippard, L., additional, Board, S., additional, and Pitt-Kerby, T., additional
Published: 2022
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25. Clinical utility and prognostic implications of the novel 4S-AF scheme to characterize and evaluate patients with atrial fibrillation:a report from ESC-EHRA EORP-AF Long-Term General Registry

Author: Ding, Wern Yew, Proietti, Marco, Boriani, Giuseppe, Fauchier, Laurent, Blomström-Lundqvist, Carina, Marin, Francisco, Potpara, Tatjana S., Lip, Gregory Y. H., Boriani, G., Lip, G. Y. H., Tavazzi, L., Maggioni, A. P., Dan, G. A., Potpara, T., Nabauer, M., Marin, F., Kalarus, Z., Fauchier, L., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., García Bolao, I., Piot, O., Etsadashvili, K., Simantirakis, E., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K. A., Erglis, A., Poposka, L., Burg, M., Crijns, H., Erküner, Atar, D., Lenarczyk, R., Martins Oliveira, M., Shah, D., Serdechnaya, E., Diker, E., Lane, D., Zëra, E., Ekmekçiu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., el Husseini, Z., Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., van Genechten, G., Heidbuchel, H., Boussy, T., de Coninck, M., van Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., van Hauwaert, B., Kuppens, C., Faes, D., van Lier, D., van Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska-Georgieva, S., Slavcheva, S., Yotov, Y., Kubíčková, M., Marni Joensen, A., Gammelmark, A., Hvilsted Rasmussen, L., Dinesen, P., Krogh Venø, S., Sorensen, B., Korsgaard, A., Andersen, K., Fragtrup Hellum, C., Svenningsen, A., Nyvad, O., Wiggers, P., May, O., Aarup, A., Graversen, B., Jensen, L., Andersen, M., Svejgaard, M., Vester, S., Hansen, S., Lynggaard, V., Ciudad, M., Vettus, R., Maestre, A., Castaño, S., Cheggour, S., Poulard, J., Mouquet, V., Leparrée, S., Bouet, J., Taieb, J., Doucy, A., Duquenne, H., Furber, A., Dupuis, J., Rautureau, J., Font, M., Damiano, P., Lacrimini, M., Abalea, J., Boismal, S., Menez, T., Mansourati, J., Range, G., Gorka, H., Laure, C., Vassalière, C., Elbaz, N., Lellouche, N., Djouadi, K., Roubille, F., Dietz, D., Davy, J., Granier, M., Winum, P., Leperchois-Jacquey, C., Kassim, H., Marijon, E., le Heuzey, J., Fedida, J., Maupain, C., Himbert, C., Gandjbakhch, E., Hidden-Lucet, F., Duthoit, G., Badenco, N., Chastre, T., Waintraub, X., Oudihat, M., Lacoste, J., Stephan, C., Bader, H., Delarche, N., Giry, L., Arnaud, D., Lopez, C., Boury, F., Brunello, I., Lefèvre, M., Mingam, R., Haissaguerre, M., le Bidan, M., Pavin, D., le Moal, V., Leclercq, C., Beitar, T., Martel, I., Schmid, A., Sadki, N., Romeyer-Bouchard, C., da Costa, A., Arnault, I., Boyer, M., Piat, C., Lozance, N., Nastevska, S., Doneva, A., Fortomaroska Milevska, B., Sheshoski, B., Petroska, K., Taneska, N., Bakrecheski, N., Lazarovska, K., Jovevska, S., Ristovski, V., Antovski, A., Lazarova, E., Kotlar, I., Taleski, J., Kedev, S., Zlatanovik, N., Jordanova, S., Bajraktarova Proseva, T., Doncovska, S., Maisuradze, D., Esakia, A., Sagirashvili, E., Lartsuliani, K., Natelashvili, N., Gumberidze, N., Gvenetadze, R., Gotonelia, N., Kuridze, N., Papiashvili, G., Menabde, I., Glöggler, S., Napp, A., Lebherz, C., Romero, H., Schmitz, K., Berger, M., Zink, M., Köster, S., Sachse, J., Vonderhagen, E., Soiron, G., Mischke, K., Reith, R., Schneider, M., Rieker, W., Boscher, D., Taschareck, A., Beer, A., Oster, D., Ritter, O., Adamczewski, J., Walter, S., Frommhold, A., Luckner, E., Richter, J., Schellner, M., Landgraf, S., Bartholome, S., Naumann, R., Schoeler, J., Westermeier, D., William, F., Wilhelm, K., Maerkl, M., Oekinghaus, R., Denart, M., Kriete, M., Tebbe, U., Scheibner, T., Gruber, M., Gerlach, A., Beckendorf, C., Anneken, L., Arnold, M., Lengerer, S., Bal, Z., Uecker, C., Förtsch, H., Fechner, S., Mages, V., Martens, E., Methe, H., Schmidt, T., Schaeffer, B., Hoffmann, B., Moser, J., Heitmann, K., Willems, S., Klaus, C., Lange, I., Durak, M., Esen, E., Mibach, F., Mibach, H., Utech, A., Gabelmann, M., Stumm, R., Ländle, V., Gartner, C., Goerg, C., Kaul, N., Messer, S., Burkhardt, D., Sander, C., Orthen, R., Kaes, S., Baumer, A., Dodos, F., Barth, A., Schaeffer, G., Gaertner, J., Winkler, J., Fahrig, A., Aring, J., Wenzel, I., Steiner, S., Kliesch, A., Kratz, E., Winter, K., Schneider, P., Haag, A., Mutscher, I., Bosch, R., Taggeselle, J., Meixner, S., Schnabel, A., Shamalla, A., Hötz, H., Korinth, A., Rheinert, C., Mehltretter, G., Schön, B., Schön, N., Starflinger, A., Englmann, E., Baytok, G., Laschinger, T., Ritscher, G., Gerth, A., Dechering, D., Eckardt, L., Kuhlmann, M., Proskynitopoulos, N., Brunn, J., Foth, K., Axthelm, C., Hohensee, H., Eberhard, K., Turbanisch, S., Hassler, N., Koestler, A., Stenzel, G., Kschiwan, D., Schwefer, M., Neiner, S., Hettwer, S., Haeussler-Schuchardt, M., Degenhardt, R., Sennhenn, S., Brendel, M., Stoehr, A., Widjaja, W., Loehndorf, S., Logemann, A., Hoskamp, J., Grundt, J., Block, M., Ulrych, R., Reithmeier, A., Panagopoulos, V., Martignani, C., Bernucci, D., Fantecchi, E., Diemberger, I., Ziacchi, M., Biffi, M., Cimaglia, P., Frisoni, J., Giannini, I., Boni, S., Fumagalli, S., Pupo, S., di Chiara, A., Mirone, P., Pesce, F., Zoccali, C., Malavasi, V. 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F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragão, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhães, P., Fontes, P., Leão, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Dan, G., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu-Andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Ioachim Popescu, M., Nistor, D., Sus, I., Coborosanu, O., Alina-Ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Vukmirovic, L., Radisavljevic, M., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Radovanovic, S., Kocijancic, A., Obrenovic-Kircanski, B., Kalimanovska Ostric, D., Simic, D., Jovanovic, I., Petrovic, I., Polovina, M., Vukicevic, M., Tomasevic, M., Mujovic, N., Radivojevic, N., Petrovic, O., Aleksandric, S., Kovacevic, V., Mijatovic, Z., Ivanovic, B., Tesic, M., Ristic, A., Vujisic-Tesic, B., Nedeljkovic, M., Karadzic, A., Uscumlic, A., Prodanovic, M., Zlatar, M., Asanin, M., Bisenic, B., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Backovic, S., Stevanovic, A., Andric, A., Pencic, B., Pavlovic-Kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric-Cupic, V., Djordjevic, D., Damjanovic, M., Zdravkovic, S., Topic, V., Stanojevic, D., Randjelovic, M., Jankovic-Tomasevic, R., Atanaskovic, V., Antic, S., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Mijatovic, S. 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Subjects: Characterization, Bleeding, 4S-AF, Atrial fibrillation, Classification, EORP-AF registry, Mortality, Prognostic implications, Stroke, Thromboembolism, Validation, Anticoagulants, Hemorrhage, Humans, Prognosis, Registries, Risk Factors, Atrial Fibrillation, Brain Ischemia, Ischemic Stroke, Physiology (medical), Cardiology and Cardiovascular Medicine
Abstract: Aims The 4S-AF classification scheme comprises of four domains: stroke risk (St), symptoms (Sy), severity of atrial fibrillation (AF) burden (Sb), and substrate (Su). We sought to examine the implementation of the 4S-AF scheme in the EORP-AF General Long-Term Registry and compare outcomes in AF patients according to the 4S-AF-led decision-making process. Methods and results Atrial fibrillation patients from 250 centres across 27 European countries were included. A 4S-AF score was calculated as the sum of each domain with a maximum score of 9. Of 6321 patients, 8.4% had low (St), 47.5% EHRA I (Sy), 40.5% newly diagnosed or paroxysmal AF (Sb), and 5.1% no cardiovascular risk factors or left atrial enlargement (Su). Median follow-up was 24 months. Using multivariable Cox regression analysis, independent predictors of all-cause mortality were (St) [adjusted hazard ratio (aHR) 8.21, 95% confidence interval (CI): 2.60–25.9], (Sb) (aHR 1.21, 95% CI: 1.08–1.35), and (Su) (aHR 1.27, 95% CI: 1.14–1.41). For CV mortality and any thromboembolic event, only (Su) (aHR 1.73, 95% CI: 1.45–2.06) and (Sy) (aHR 1.29, 95% CI: 1.00–1.66) were statistically significant, respectively. None of the domains were independently linked to ischaemic stroke or major bleeding. Higher 4S-AF score was related to a significant increase in all-cause mortality, CV mortality, any thromboembolic event, and ischaemic stroke but not major bleeding. Treatment of all 4S-AF domains was associated with an independent decrease in all-cause mortality (aHR 0.71, 95% CI: 0.55–0.92). For each 4S-AF domain left untreated, the risk of all-cause mortality increased substantially (aHR 1.35, 95% CI: 1.16–1.56). Conclusion Implementation of the novel 4S-AF scheme is feasible, and treatment decisions based on this scheme improve mortality rates in AF.
Published: 2022
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26. Health Care Quality in CKD Subjects: A Cross-Sectional In-Hospital Evaluation

Author: Rzayeva, L., primary, Matyukhin, I., additional, Ritter, O., additional, Patschan, S., additional, and Patschan, D., additional
Published: 2022
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27. Elmar - Electromagnetic Recorder

Author: Ritter, O., Rettig, S., Schmitt, R., Müller-Brettschneider, C., and Weckmann, U.
Published: 2022

28. Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry

Author: Proietti, M., Vitolo, M., Harrison, S. L., Lane, D. A., Fauchier, L., Marin, F., Nabauer, M., Potpara, T. S., Dan, G. -A., Boriani, G., Lip, G. Y. H., Boriani (Chair), G., Tavazzi, L., Maggioni, A. P., Potpara, T., Kalarus, Z., Ferrari, R., Shantsila, A., Goda, A., Mairesse, G., Shalganov, T., Antoniades, L., Taborsky, M., Riahi, S., Muda, P., Garcia Bolao, I., Piot, O., Etsadashvili, K., Simantirakis, E. N., Haim, M., Azhari, A., Najafian, J., Santini, M., Mirrakhimov, E., Kulzida, K., Erglis, A., Poposka, L., Burg, M. R., Crijns, H., Erkuner, O., Atar, D., Lenarczyk, R., Martins Oliveira, M., Shah, D., Serdechnaya, E., Diker, E., Lane, D., Zera, E., Ekmekciu, U., Paparisto, V., Tase, M., Gjergo, H., Dragoti, J., Ciutea, M., Ahadi, N., el Husseini, Z., Raepers, M., Leroy, J., Haushan, P., Jourdan, A., Lepiece, C., Desteghe, L., Vijgen, J., Koopman, P., Van Genechten, G., Heidbuchel, H., Boussy, T., De Coninck, M., Van Eeckhoutte, H., Bouckaert, N., Friart, A., Boreux, J., Arend, C., Evrard, P., Stefan, L., Hoffer, E., Herzet, J., Massoz, M., Celentano, C., Sprynger, M., Pierard, L., Melon, P., Van Hauwaert, B., Kuppens, C., Faes, D., Van Lier, D., Van Dorpe, A., Gerardy, A., Deceuninck, O., Xhaet, O., Dormal, F., Ballant, E., Blommaert, D., Yakova, D., Hristov, M., Yncheva, T., Stancheva, N., Tisheva, S., Tokmakova, M., Nikolov, F., Gencheva, D., Kunev, B., Stoyanov, M., Marchov, D., Gelev, V., Traykov, V., Kisheva, A., Tsvyatkov, H., Shtereva, R., Bakalska-Georgieva, S., Slavcheva, S., Yotov, Y., Kubickova, M., Marni Joensen, A., Gammelmark, A., Hvilsted Rasmussen, L., Dinesen, P., Krogh Veno, S., Sorensen, B., Korsgaard, A., Andersen, K., Fragtrup Hellum, C., Svenningsen, A., Nyvad, O., Wiggers, P., May, O., Aarup, A., Graversen, B., Jensen, L., Andersen, M., Svejgaard, M., Vester, S., Hansen, S., Lynggaard, V., Ciudad, M., Vettus, R., Maestre, A., Castano, S., Cheggour, S., Poulard, J., Mouquet, V., Leparree, S., Bouet, J., Taieb, J., Doucy, A., Duquenne, H., Furber, A., Dupuis, J., Rautureau, J., Font, M., Damiano, P., Lacrimini, M., Abalea, J., Boismal, S., Menez, T., Mansourati, J., Range, G., Gorka, H., Laure, C., Vassaliere, C., Elbaz, N., Lellouche, N., Djouadi, K., Roubille, F., Dietz, D., Davy, J., Granier, M., Winum, P., Leperchois-Jacquey, C., Kassim, H., Marijon, E., Le Heuzey, J., Fedida, J., Maupain, C., Himbert, C., Gandjbakhch, E., Hidden-Lucet, F., Duthoit, G., Badenco, N., Chastre, T., Waintraub, X., Oudihat, M., Lacoste, J., Stephan, C., Bader, H., Delarche, N., Giry, L., Arnaud, D., Lopez, C., Boury, F., Brunello, I., Lefevre, M., Mingam, R., Haissaguerre, M., Le Bidan, M., Pavin, D., Le Moal, V., Leclercq, C., Beitar, T., Martel, I., Schmid, A., Sadki, N., Romeyer-Bouchard, C., Da Costa, A., Arnault, I., Boyer, M., Piat, C., Lozance, N., Nastevska, S., Doneva, A., Fortomaroska Milevska, B., Sheshoski, B., Petroska, K., Taneska, N., Bakrecheski, N., Lazarovska, K., Jovevska, S., Ristovski, V., Antovski, A., Lazarova, E., Kotlar, I., Taleski, J., Kedev, S., Zlatanovik, N., Jordanova, S., Bajraktarova Proseva, T., Doncovska, S., Maisuradze, D., Esakia, A., Sagirashvili, E., Lartsuliani, K., Natelashvili, N., Gumberidze, N., Gvenetadze, R., Gotonelia, N., Kuridze, N., Papiashvili, G., Menabde, I., Gloggler, S., Napp, A., Lebherz, C., Romero, H., Schmitz, K., Berger, M., Zink, M., Koster, S., Sachse, J., Vonderhagen, E., Soiron, G., Mischke, K., Reith, R., Schneider, M., Rieker, W., Boscher, D., Taschareck, A., Beer, A., Oster, D., Ritter, O., Adamczewski, J., Walter, S., Frommhold, A., Luckner, E., Richter, J., Schellner, M., Landgraf, S., Bartholome, S., Naumann, R., Schoeler, J., Westermeier, D., William, F., Wilhelm, K., Maerkl, M., Oekinghaus, R., Denart, M., Kriete, M., Tebbe, U., Scheibner, T., Gruber, M., Gerlach, A., Beckendorf, C., Anneken, L., Arnold, M., Lengerer, S., Bal, Z., Uecker, C., Fortsch, H., Fechner, S., Mages, V., Martens, E., Methe, H., Schmidt, T., Schaeffer, B., Hoffmann, B., Moser, J., Heitmann, K., Willems, S., Klaus, C., Lange, I., Durak, M., Esen, E., Mibach, F., Mibach, H., Utech, A., Gabelmann, M., Stumm, R., Landle, V., Gartner, C., Goerg, C., Kaul, N., Messer, S., Burkhardt, D., Sander, C., Orthen, R., Kaes, S., Baumer, A., Dodos, F., Barth, A., Schaeffer, G., Gaertner, J., Winkler, J., Fahrig, A., Aring, J., Wenzel, I., Steiner, S., Kliesch, A., Kratz, E., Winter, K., Schneider, P., Haag, A., Mutscher, I., Bosch, R., Taggeselle, J., Meixner, S., Schnabel, A., Shamalla, A., Hotz, H., Korinth, A., Rheinert, C., Mehltretter, G., Schon, B., Schon, N., Starflinger, A., Englmann, E., Baytok, G., Laschinger, T., Ritscher, G., Gerth, A., Dechering, D., Eckardt, L., Kuhlmann, M., Proskynitopoulos, N., Brunn, J., Foth, K., Axthelm, C., Hohensee, H., Eberhard, K., Turbanisch, S., Hassler, N., Koestler, A., Stenzel, G., Kschiwan, D., Schwefer, M., Neiner, S., Hettwer, S., Haeussler-Schuchardt, M., Degenhardt, R., Sennhenn, S., Brendel, M., Stoehr, A., Widjaja, W., Loehndorf, S., Logemann, A., Hoskamp, J., Grundt, J., Block, M., Ulrych, R., Reithmeier, A., Panagopoulos, V., Martignani, C., Bernucci, D., Fantecchi, E., Diemberger, I., Ziacchi, M., Biffi, M., Cimaglia, P., Frisoni, J., Giannini, I., Boni, S., Fumagalli, S., Pupo, S., Di Chiara, A., Mirone, P., Pesce, F., Zoccali, C., Malavasi, V. L., Mussagaliyeva, A., Ahyt, B., Salihova, Z., Koshum-Bayeva, K., Kerimkulova, A., Bairamukova, A., Lurina, B., Zuzans, R., Jegere, S., Mintale, I., Kupics, K., Jubele, K., Kalejs, O., Vanhear, K., Burg, M., Cachia, M., Abela, E., Warwicker, S., Tabone, T., Xuereb, R., Asanovic, D., Drakalovic, D., Vukmirovic, M., Pavlovic, N., Music, L., Bulatovic, N., Boskovic, A., Uiterwaal, H., Bijsterveld, N., De Groot, J., Neefs, J., van den Berg, N., Piersma, F., Wilde, A., Hagens, V., Van Es, J., Van Opstal, J., Van Rennes, B., Verheij, H., Breukers, W., Tjeerdsma, G., Nijmeijer, R., Wegink, D., Binnema, R., Said, S., Philippens, S., van Doorn, W., Szili-Torok, T., Bhagwandien, R., Janse, P., Muskens, A., van Eck, M., Gevers, R., van der Ven, N., Duygun, A., Rahel, B., Meeder, J., Vold, A., Holst Hansen, C., Engset, I., Dyduch-Fejklowicz, B., Koba, E., Cichocka, M., Sokal, A., Kubicius, A., Pruchniewicz, E., Kowalik-Sztylc, A., Czapla, W., Mroz, I., Kozlowski, M., Pawlowski, T., Tendera, M., Winiarska-Filipek, A., Fidyk, A., Slowikowski, A., Haberka, M., Lachor-Broda, M., Biedron, M., Gasior, Z., Kolodziej, M., Janion, M., Gorczyca-Michta, I., Wozakowska-Kaplon, B., Stasiak, M., Jakubowski, P., Ciurus, T., Drozdz, J., Simiera, M., Zajac, P., Wcislo, T., Zycinski, P., Kasprzak, J., Olejnik, A., Harc-Dyl, E., Miarka, J., Pasieka, M., Zieminska-Luc, M., Bujak, W., Sliwinski, A., Grech, A., Morka, J., Petrykowska, K., Prasal, M., Hordynski, G., Feusette, P., Lipski, P., Wester, A., Streb, W., Romanek, J., Wozniak, P., Chlebus, M., Szafarz, P., Stanik, W., Zakrzewski, M., Kazmierczak, J., Przybylska, A., Skorek, E., Blaszczyk, H., Stepien, M., Szabowski, S., Krysiak, W., Szymanska, M., Karasinski, J., Blicharz, J., Skura, M., Halas, K., Michalczyk, L., Orski, Z., Krzyzanowski, K., Skrobowski, A., Zielinski, L., Tomaszewska-Kiecana, M., Dluzniewski, M., Kiliszek, M., Peller, M., Budnik, M., Balsam, P., Opolski, G., Tyminska, A., Ozieranski, K., Wancerz, A., Borowiec, A., Majos, E., Dabrowski, R., Szwed, H., Musialik-Lydka, A., Leopold-Jadczyk, A., Jedrzejczyk-Patej, E., Koziel, M., Mazurek, M., Krzemien-Wolska, K., Starosta, P., Nowalany-Kozielska, E., Orzechowska, A., Szpot, M., Staszel, M., Almeida, S., Pereira, H., Brandao Alves, L., Miranda, R., Ribeiro, L., Costa, F., Morgado, F., Carmo, P., Galvao Santos, P., Bernardo, R., Adragao, P., Ferreira da Silva, G., Peres, M., Alves, M., Leal, M., Cordeiro, A., Magalhaes, P., Fontes, P., Leao, S., Delgado, A., Costa, A., Marmelo, B., Rodrigues, B., Moreira, D., Santos, J., Santos, L., Terchet, A., Darabantiu, D., Mercea, S., Turcin Halka, V., Pop Moldovan, A., Gabor, A., Doka, B., Catanescu, G., Rus, H., Oboroceanu, L., Bobescu, E., Popescu, R., Dan, A., Buzea, A., Daha, I., Dan, G., Neuhoff, I., Baluta, M., Ploesteanu, R., Dumitrache, N., Vintila, M., Daraban, A., Japie, C., Badila, E., Tewelde, H., Hostiuc, M., Frunza, S., Tintea, E., Bartos, D., Ciobanu, A., Popescu, I., Toma, N., Gherghinescu, C., Cretu, D., Patrascu, N., Stoicescu, C., Udroiu, C., Bicescu, G., Vintila, V., Vinereanu, D., Cinteza, M., Rimbas, R., Grecu, M., Cozma, A., Boros, F., Ille, M., Tica, O., Tor, R., Corina, A., Jeewooth, A., Maria, B., Georgiana, C., Natalia, C., Alin, D., Dinu-Andrei, D., Livia, M., Daniela, R., Larisa, R., Umaar, S., Tamara, T., Loachim Popescu, M., Nistor, D., Sus, I., Coborosanu, O., Alina-Ramona, N., Dan, R., Petrescu, L., Ionescu, G., Vacarescu, C., Goanta, E., Mangea, M., Ionac, A., Mornos, C., Cozma, D., Pescariu, S., Solodovnicova, E., Soldatova, I., Shutova, J., Tjuleneva, L., Zubova, T., Uskov, V., Obukhov, D., Rusanova, G., Isakova, N., Odinsova, S., Arhipova, T., Kazakevich, E., Zavyalova, O., Novikova, T., Riabaia, I., Zhigalov, S., Drozdova, E., Luchkina, I., Monogarova, Y., Hegya, D., Rodionova, L., Nevzorova, V., Lusanova, O., Arandjelovic, A., Toncev, D., Milanov, M., Sekularac, N., Zdravkovic, M., Hinic, S., Dimkovic, S., Acimovic, T., Saric, J., Polovina, M., Vujisic-Tesic, B., Nedeljkovic, M., Zlatar, M., Asanin, M., Vasic, V., Popovic, Z., Djikic, D., Sipic, M., Peric, V., Dejanovic, B., Milosevic, N., Stevanovic, A., Andric, A., Pencic, B., Pavlovic-Kleut, M., Celic, V., Pavlovic, M., Petrovic, M., Vuleta, M., Petrovic, N., Simovic, S., Savovic, Z., Milanov, S., Davidovic, G., Iric-Cupic, V., Simonovic, D., Stojanovic, M., Stojanovic, S., Mitic, V., Ilic, V., Petrovic, D., Deljanin Ilic, M., Ilic, S., Stoickov, V., Markovic, S., Kovacevic, S., Garcia Fernandez, A., Perez Cabeza, A., Anguita, M., Tercedor Sanchez, L., Mau, E., Loayssa, J., Ayarra, M., Carpintero, M., Roldan Rabadan, I., Gil Ortega, M., Tello Montoliu, A., Orenes Pinero, E., Manzano Fernandez, S., Romero Aniorte, A., Veliz Martinez, A., Quintana Giner, M., Ballesteros, G., Palacio, M., Alcalde, O., Garcia-Bolao, I., Bertomeu Gonzalez, V., Otero-Ravina, F., Garcia Seara, J., Gonzalez Juanatey, J., Dayal, N., Maziarski, P., Gentil-Baron, P., Koc, M., Onrat, E., Dural, I. E., Yilmaz, K., Ozin, B., Tan Kurklu, S., Atmaca, Y., Canpolat, U., Tokgozoglu, L., Dolu, A. K., Demirtas, B., Sahin, D., Ozcan Celebi, O., Gagirci, G., Turk, U. O., Ari, H., Polat, N., Toprak, N., Sucu, M., Akin Serdar, O., Taha Alper, A., Kepez, A., Yuksel, Y., Uzunselvi, A., Yuksel, S., Sahin, M., Kayapinar, O., Ozcan, T., Kaya, H., Yilmaz, M. B., Kutlu, M., Demir, M., Gibbs, C., Kaminskiene, S., Bryce, M., Skinner, A., Belcher, G., Hunt, J., Stancombe, L., Holbrook, B., Peters, C., Tettersell, S., Senoo, K., Russell, K., Domingos, P., Hussain, S., Partridge, J., Haynes, R., Bahadur, S., Brown, R., Mcmahon, S., Lip, G., Mcdonald, J., Balachandran, K., Singh, R., Garg, S., Desai, H., Davies, K., Goddard, W., Galasko, G., Rahman, I., Chua, Y., Payne, O., Preston, S., Brennan, O., Pedley, L., Whiteside, C., Dickinson, C., Brown, J., Jones, K., Benham, L., Brady, R., Buchanan, L., Ashton, A., Crowther, H., Fairlamb, H., Thornthwaite, S., Relph, C., Mcskeane, A., Poultney, U., Kelsall, N., Rice, P., Wilson, T., Wrigley, M., Kaba, R., Patel, T., Young, E., Law, J., Runnett, C., Thomas, H., Mckie, H., Fuller, J., Pick, S., Sharp, A., Hunt, A., Thorpe, K., Hardman, C., Cusack, E., Adams, L., Hough, M., Keenan, S., Bowring, A., Watts, J., Zaman, J., Goffin, K., Nutt, H., Beerachee, Y., Featherstone, J., Mills, C., Pearson, J., Stephenson, L., Grant, S., Wilson, A., Hawksworth, C., Alam, I., Robinson, M., Ryan, S., Egdell, R., Gibson, E., Holland, M., Leonard, D., Mishra, B., Ahmad, S., Randall, H., Hill, J., Reid, L., George, M., Mckinley, S., Brockway, L., Milligan, W., Sobolewska, J., Muir, J., Tuckis, L., Winstanley, L., Jacob, P., Kaye, S., Morby, L., Jan, A., Sewell, T., Boos, C., Wadams, B., Cope, C., Jefferey, P., Andrews, N., Getty, A., Suttling, A., Turner, C., Hudson, K., Austin, R., Howe, S., Iqbal, R., Gandhi, N., Brophy, K., Mirza, P., Willard, E., Collins, S., Ndlovu, N., Subkovas, E., Karthikeyan, V., Waggett, L., Wood, A., Bolger, A., Stockport, J., Evans, L., Harman, E., Starling, J., Williams, L., Saul, V., Sinha, M., Bell, L., Tudgay, S., Kemp, S., Frost, L., Ingram, T., Loughlin, A., Adams, C., Adams, M., Hurford, F., Owen, C., Miller, C., Donaldson, D., Tivenan, H., Button, H., Nasser, A., Jhagra, O., Stidolph, B., Brown, C., Livingstone, C., Duffy, M., Madgwick, P., Roberts, P., Greenwood, E., Fletcher, L., Beveridge, M., Earles, S., Mckenzie, D., Beacock, D., Dayer, M., Seddon, M., Greenwell, D., Luxton, F., Venn, F., Mills, H., Rewbury, J., James, K., Roberts, K., Tonks, L., Felmeden, D., Taggu, W., Summerhayes, A., Hughes, D., Sutton, J., Felmeden, L., Khan, M., Walker, E., Norris, L., O'Donohoe, L., Mozid, A., Dymond, H., Lloyd-Jones, H., Saunders, G., Simmons, D., Coles, D., Cotterill, D., Beech, S., Kidd, S., Wrigley, B., Petkar, S., Smallwood, A., Jones, R., Radford, E., Milgate, S., Metherell, S., Cottam, V., Buckley, C., Broadley, A., Wood, D., Allison, J., Rennie, K., Balian, L., Howard, L., Pippard, L., Board, S., Pitt-Kerby, T., Proietti M, Vitolo M, Harrison SL, Lane DA, Fauchier L, Marin F, Nabauer M, Potpara TS, Dan GA, Boriani G, Lip GYH, ESC-EHRA EORP-AF Long-Term General Registry Investigators, Diemberger I, Ziacchi M, Frisoni J, Cardiology, ACS - Heart failure & arrhythmias, Graduate School, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de cardiologie
Subjects: Registrie, Research Report, medicine.medical_specialty, Major adverse outcome, Cardiovascular risk factors, Cluster analysis, Risk Factors, Internal medicine, Clinical phenotype, Atrial Fibrillation, Epidemiology, Humans, Medicine, Registries, Cluster analysi, Atrial fibrillation, Clinical management, Clinical phenotypes, Major adverse outcomes, Phenotype, business.industry, Proportional hazards model, Risk Factor, Hazard ratio, General Medicine, medicine.disease, Confidence interval, Cohort, Observational study, business, Research Article, Human
Abstract: Background Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients’ clinical phenotypes and analyse the differential clinical course. Methods We performed a hierarchical cluster analysis based on Ward’s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results A total of 9363 were available for this analysis. We identified three clusters: Cluster 1 (n = 3634; 38.8%) characterized by older patients and prevalent non-cardiac comorbidities; Cluster 2 (n = 2774; 29.6%) characterized by younger patients with low prevalence of comorbidities; Cluster 3 (n = 2955;31.6%) characterized by patients’ prevalent cardiovascular risk factors/comorbidities. Over a mean follow-up of 22.5 months, Cluster 3 had the highest rate of cardiovascular events, all-cause death, and the composite outcome (combining the previous two) compared to Cluster 1 and Cluster 2 (all P < .001). An adjusted Cox regression showed that compared to Cluster 2, Cluster 3 (hazard ratio (HR) 2.87, 95% confidence interval (CI) 2.27–3.62; HR 3.42, 95%CI 2.72–4.31; HR 2.79, 95%CI 2.32–3.35), and Cluster 1 (HR 1.88, 95%CI 1.48–2.38; HR 2.50, 95%CI 1.98–3.15; HR 2.09, 95%CI 1.74–2.51) reported a higher risk for the three outcomes respectively. Conclusions In European AF patients, three main clusters were identified, differentiated by differential presence of comorbidities. Both non-cardiac and cardiac comorbidities clusters were found to be associated with an increased risk of major adverse outcomes.
Published: 2021
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29. High-density lipoprotein lipid peroxidation in association with presence of coronary artery disease and atrial fibrillation in a large cross-sectional study

Author: Pagonas, N, primary, Sasko, B, additional, Mueller, R, additional, Jaensch, M, additional, Dammermann, W, additional, Hillmeister, P, additional, Buschmann, I, additional, Ritter, O, additional, Westhoff, T H, additional, and Kelesidis, T, additional
Published: 2021
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30. ICD exchange in the elderly

Author: Ritter, O, primary, Pagonas, N, additional, Eisert, M, additional, Patschan, D, additional, Nordbeck, P, additional, Buschmann, I, additional, Sasko, B, additional, and Andresen, H, additional
Published: 2021
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31. Investigations regarding the role of NOS1AP in the heart using a conditional overexpression mouse model

Author: Jaensch, M, primary, Trum, M, additional, Williams, T, additional, Schmitt, J, additional, Schuh, K, additional, Qadri, F, additional, Maier, L, additional, Bader, M, additional, and Ritter, O, additional
Published: 2021
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32. Magnetotelluric measurements in the Mérida Andes, western Venezuela

Author: Ritter, O., Cruces-Zabala, J., Weckmann, U., Tietze, K., Schmitt, R., and Schmitz, M.
Abstract: The 100 km wide Mérida Andes extend from the Colombian/Venezuelan border to the Caribbean coast. To the north and south, the Mérida Andes are bound by hydrocarbon-rich sedimentary basins. This mountain chain and its associated major strike-slip fault systems formed by the oblique convergence of the Caribbean with the South American Plate and the north-eastwards expulsion of the North Andean Block in western Venezuela. In 2013, the Integrated Geoscience of the Mérida Andes Project (the GIAME project) was initiated to image the Mérida Andes on a lithospheric scale and to develop a dynamic model of their evolution by integrating wide-angle seismic, magnetotelluric and potential field data. Magnetotelluric (MT) dataset was acquired in 2015 along a 240 km long profile across the Mérida Andes. MT studies of orogens often reveal complex resistivity structures, typically associated with active deformation and characterized by high electrical conductivity zones. Fluids in fault systems and fluids derived from remineralization reactions of hydrous minerals often characterise high conductivity in active tectonic regimes. Cruces-Zabala et al. (2020) identified conductive zones with up to 10 km depth for the Maracaibo Basin and 5 km for the Barinas - Apure Basin. The Mérida Andes are charaterized by high resistivity separated by several conductive anomalies that corelate spatialy to the fault systems at the surface. A conductive zone a great depth (>50km) was identified as a projection of the detachment surface of the Trujillo Block to the east. This data publication encompasses a detailed report in pdf format with a description of the project, information on the experimental setup, data collection, instrumentation used, recording configuration and data quality. The folder structure and content of the data repository are described in detail in Ritter et al. (2019). Time-series data are provided in EMERALD format (Ritter et al., 2015).
Published: 2021

33. Magnetotelluric and Radiomagnetotelluric measurements near Geyer in the Ore Mountains, Germany

Author: Ritter, O., Patzer, C., Cruces-Zabala, J., Hemmens, E., Arend, I., and Weckmann, U.
Abstract: The region of Geyer in the Ore Mountains (Erzgebirge) of Germany, situated approximately 110 kilometres south of Leipzig, has a long history of ore mining. The region is known for its deposits of tin, zinc, tungsten, molybdenum, copper, iron, silver, and indium. Due to this long history and known reservoir potential, this area was selected as a test site for the Innovative, Non-invasive and Fully Acceptable Exploration Technologies (INFACT) project. INFACT is a EU funded project aiming to foster new and innovative non-invasive methods for the exploration of new mineral deposits and is coordinated by the Helmholtz Institute Freiberg for Resource Technology (HIF) at Helmholtz-Zentrum Dresden-Rossendorf (HZDR). Within the framework of this project, the GFZ - German Research Centre for Geosciences, Potsdam, Germany, acquired magnetotelluric (MT) and radiomagnetotelluric (RMT) data near Geyer. The main objectives of these measurements were to map the shallow subsurface for mineral deposits and to evaluate the potential of these methods in densely populated areas with high levels of anthropogenic noise. This data publication (10.5880/GIPP-MT.201933.1) encompasses a detailed report in pdf format with a description of the project, information on the experimental setup, data collection, instrumentation used, recording configuration and data quality. The folder structure and content of the data repository are described in detail in Ritter et al. (2019). Time-series data are provided in EMERALD format (Ritter et al., 2015).
Published: 2021

34. Magnetotelluric measurements in the Mérida Andes, western Venezuela - Report on the magnetotelluric data in the project/repository folder: GIAME.2015

Author: Ritter, O., Cruces-Zabala, J., Weckmann, U., Tietze, K., Schmitt, R., and Schmitz, M.
Published: 2021

35. Tele-QoL - finale Ergebnisse eines Projekts zur Entwicklung eines settingbezogenen Instruments zur Messung der Lebensqualität im Kontext telemedizinischer Anwendungen

Author: Greffin, K, Mühlan, H, van den Berg, N, Hoffmann, W, Ritter, O, Oeff, M, Schomerus, G, Speerforck, S, Schmidt, S, Greffin, K, Mühlan, H, van den Berg, N, Hoffmann, W, Ritter, O, Oeff, M, Schomerus, G, Speerforck, S, and Schmidt, S
Published: 2021

36. An unusual finding after resuscitation: contusio cordis

Author: Reiter, T., Ritter, O., Beer, M., and Petritsch, B.
Published: 2012
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37. Hotline update of clinical trials and registries presented at the German Cardiac Society meeting 2008: (PEPCAD, LokalTax, INH, German ablation registry, German device registry, DES.DE registry, DHR, Reality, SWEETHEART registry, ADMA, GERSHWIN)

Author: Maier, L. S., Maack, C., Ritter, O., and Böhm, M.
Published: 2008
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38. AKI Epidemiology and Outcomes: A Retrospective Cohort Study from the Prenephrology Era

Author: Asmus, K., primary, Erfurt, S., additional, Ritter, O., additional, Patschan, S., additional, and Patschan, D., additional
Published: 2021
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39. MT_ANT2 : magnetotelluric measurements around Neumayer Station III, Antarctica

Author: Ritter, O., Fromm, T., and Weckmann, U.
Abstract: Magnetotellurics (MT) is a geophysical deep sounding tool that can help decipher the deep hydrology and geology of Antarctica, in concert with more established and already applied geophysical methods, such as seismology, gravity, and magnetics. Electrical conductivity is an important physical parameter to identify properties of rocks and, perhaps more importantly, constituents within, such as fluids or mineralisation. The unique conditions of Antarctica, which is largely covered with ice cause technical issues, particularly with the electric field recordings, as highly resistive snow and ice at surface of Antarctica hampers contact of the E-field sensors (telluric electrodes) with the ground. The project was a feasibility study to address this principal problem and to test modified MT equipment of the Geophysical Instrument Pool Potsdam (GIPP) in the vicinity of the Neumayer Station III (NMIII) on the Ekström Ice Shelfon. This data publication encompasses a detailed report in .pdf format with a description of the project, information on the experimental setup, data collection, instrumentation used, recording configuration and data quality. The folder structure and content of the data repository are described in detail in Ritter et al. (2019). Time-series data are provided in EMERALD format (Ritter et al., 2015).
Published: 2020

40. Settingsensitive Konzeptualisierung und Erfassung der Lebensqualität in der telemedizinischen Versorgung (Tele-QoL): Entwicklungsstand und Pilotierungsergebnisse

Author: Greffin, K, Mühlan, H, van den Berg, N, Hoffmann, W, Ritter, O, Oeff, M, Schomerus, G, Schmidt, S, Greffin, K, Mühlan, H, van den Berg, N, Hoffmann, W, Ritter, O, Oeff, M, Schomerus, G, and Schmidt, S
Published: 2020

41. PAC-Mediated AKI Protection Is Critically Mediated but Does Not Exclusively Depend on Cell-Derived Microvesicles

Author: Dihazi, H., primary, Schwarze, K., additional, Patschan, S., additional, Müller, G. A., additional, Ritter, O., additional, Zeisberg, M., additional, and Patschan, D., additional
Published: 2021
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42. Fonction pulmonaire à 3 mois des patients survivants à la réanimation du SARS-CoV-2

Author: Eberst, G., primary, Claudé, F., additional, Laurent, L., additional, Paget-Bailly, S., additional, Meurisse, A., additional, Vernerey, D., additional, Roux-Claudé, P., additional, Bouiller, K., additional, Chirouze, C., additional, Grillet, F., additional, Behr, J., additional, Ritter, O., additional, Capellier, G., additional, Pili-Floury, S., additional, Bonniaud, P., additional, Georges, M., additional, and Westeel, V., additional
Published: 2021
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43. Myokardinfarkt nach Influenza-Schutzimpfung

Author: Ritter, O., Bonz, A., Strotmann, J., and Langenfeld, H.
Published: 2003
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44. Pseudo-remote reference processing of magnetotelluric data: a fast and efficient data acquisition scheme for local arrays

Author: Muñoz, G. and Ritter, O.
Published: 2013
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45. MR safety: Fast T1 thermometry of the RF-induced heating of medical devices

Author: Gensler, D., Fidler, F., Ehses, P., Warmuth, M., Reiter, T., Düring, M., Ritter, O., Ladd, M. E., Quick, H. H., Jakob, P. M., Bauer, W. R., and Nordbeck, P.
Published: 2012
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46. Oxidation of HDL in patients with coronary artery disease

Author: Pagonas, N, primary, Mueller, R, additional, Weiland, L, additional, Jaensch, M, additional, Westhoff, T.H, additional, Buschmann, I.R, additional, Sasko, B, additional, Ritter, O, additional, and Kelesidis, T.H, additional
Published: 2020
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47. Magnetotelluric imaging of the Mérida Andes and surrounding areas in Venezuela

Author: Cruces-Zabala, J, primary, Ritter, O, primary, Weckmann, U, primary, Tietze, K, primary, and Schmitz, M, primary
Published: 2020
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48. PAC-mediated AKI protection is critically mediated but does not exclusively depend on cell-derived microvesicles

Author: Dihazi, H., primary, Schwarze, K., additional, Patschan, S., additional, Müller, G.A., additional, Ritter, O., additional, and Patschan, D., additional
Published: 2020
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49. Pharmacological pre– and post–conditioning with the sphingosine–1–phosphate receptor modulator FTY720 after myocardial ischaemia–reperfusion

Author: Hofmann, U, Hu, K, Walter, F, Burkard, N, Ertl, G, Bauersachs, J, Ritter, O, Frantz, S, and Bonz, A
Published: 2010
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50. Combination of transvaginal sonography and clinical examination for preoperative diagnosis of pelvic endometriosis

Author: Hudelist, G, Oberwinkler, KH, Singer, CF, Tuttlies, F, Rauter, G, Ritter, O, and Keckstein, J
Published: 2009

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