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An experimental study was conducted to evaluate the effectiveness of structured teaching programme on suicidal prevention among ANM students in Royal Institute of Nursing, Jaito Sarja. The research design used in this study was one group pretest-posttest design. Total 50 A.N.M students were selected by convenient sampling. The tool used for study was self-structured questionnaire. Major findings of the study revealed that in pre-test, majority 31 (62.0%) of them had inadequate knowledge, 19 (38.0%) had moderately adequate knowledge and none of them had adequate knowledge where as in post-test majority 29 (58.0%) of them had adequate knowledge, whereas 21 (42.0%) of them had moderately adequate knowledge and none of them had inadequate knowledge. Post test score was greater than pretest score hence, research hypothesis (H1) was accepted. The association between the post-test knowledge and demographic variables such as age, occupation of parents were found to be statistically significant and religion, domiciliary area, type of family, Education of parents, source of information, annual family income, source of income, any history of suicide in family and family history of mental illness were found to be statistically non-significant.