277 results on '"Rinné, Susanne"'
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2. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
3. Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5
4. Correction: Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
5. Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
6. Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function
7. KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures
8. Polypharmacological Modulation of Atrial Fibrillation: Rational Design, Synthesis, and Evaluation of Novel Compounds Targeting NaV1.5, KV1.5, and K2P Channels
9. Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease
10. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
11. Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease
12. POPDC2 a novel susceptibility gene for conduction disorders
13. Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking
14. A lower X-gate in TASK channels traps inhibitors within the vestibule
15. Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish
16. Increased KCNJ18 promoter activity as a mechanism in atypical normokalemic periodic paralysis
17. Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants
18. TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes
19. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome
20. Whole Exome Sequencing Identifies a Heterozygous Variant in the Cav1.3 Gene CACNA1D Associated with Familial Sinus Node Dysfunction and Focal Idiopathic Epilepsy
21. Selective TASK-1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability
22. POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart
23. Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking
24. Hyperinsulinemic Hypoglycemia Associated with a CaV1.2 Variant with Mixed Gain- and Loss-of-Function Effects
25. Electrophysiological characterization of a large set of novel variants in the SCN5A-gene: identification of novel LQTS3 and BrS mutations
26. Acetylcholine‐dependent upregulation of TASK‐1 channels in thalamic interneurons by a smooth muscle‐like signalling pathway
27. Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?
28. The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias
29. A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Ion Channels
30. Modulation of Kv1.5 channel expression and function by the sigma 1 receptor
31. A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels
32. POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking
33. Soluble polysialylated NCAM: a novel player of the innate immune system in the lung
34. Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness
35. Hyperinsulinemic Hypoglycemia Associated with a Ca V 1.2 Variant with Mixed Gain- and Loss-of-Function Effects.
36. Side pockets provide the basis for a new mechanism of Kv channel–specific inhibition
37. Non dominant-negative KCNJ2 gene mutations leading to Andersen-Tawil syndrome with an isolated cardiac phenotype
38. 5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis
39. Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategy
40. Identification of a critical binding site for local anaesthetics in the side pockets of K v 1 channels
41. New Cav1.2 Channelopathy with High-Functioning Autism, Affective Disorder, Severe Dental Enamel Defects, a Short QT Interval, and a Novel CACNA1C Loss-of-Function Mutation
42. Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder
43. Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategy.
44. Structural Basis for Gating of the Two-Pore Domain K+ (K2P) Channels TASK-1 and TALK-2
45. Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system
46. New Cav1.2 Channelopathy with High-Functioning Autism, Affective Disorder, Severe Dental Enamel Defects, a Short QT Interval, and a Novel CACNA1C Loss-of-Function Mutation
47. Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice
48. Characterisation of the Versatile Gating Behaviour in Talk-2 K2P Channels
49. POPDC3Gene Variants Associate with a New Form of Limb Girdle Muscular Dystrophy
50. Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins
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