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Your search keyword '"Rinaudo, Daniela"' showing total 18 results
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18 results on '"Rinaudo, Daniela"'

1. Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study

Author

Lohrmann, Florens, Efstratiou, Androulla, Sørensen, Uffe B. Skov, Creti, Roberta, Decheva, Antoaneta, Křížová, Pavla, Kozáková, Jana, Rodriguez-Granger, Javier, De La Rosa Fraile, Manuel, Margarit, Immaculada, Rinaudo, Daniela, Maione, Domenico, Telford, John, Orefici, Graziella, Kilian, Mogens, Afshar, Baharak, Melin, Pierrette, Berner, Reinhard, Hufnagel, Markus, and Kunze, Mirjam

Published
2024
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2. Neonatal invasive disease caused by Streptococcus agalactiae in Europe: the DEVANI multi-center study

Author

Lohrmann, Florens, Hufnagel, Markus, Kunze, Mirjam, Afshar, Baharak, Creti, Roberta, Detcheva, Antoaneta, Kozakova, Jana, Rodriguez-Granger, Javier, Sørensen, Uffe B. Skov, Margarit, Immaculada, Maione, Domenico, Rinaudo, Daniela, Orefici, Graziella, Telford, John, de la Rosa Fraile, Manuel, Kilian, Mogens, Efstratiou, Androulla, Berner, Reinhard, and Melin, Pierrette

Published
2023
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4. Complete Genome Sequence and Comparative Genomic Analysis of an Emerging Human Pathogen, Serotype V Streptococcus agalactiae

Author

Tettelin, Hervé, Masignani, Vega, Cieslewicz, Michael J., Eisen, Jonathan A., Peterson, Scott, Wessels, Michael R., Paulsen, Ian T., Nelson, Karen E., Margarit, Immaculada, Read, Timothy D., Madoff, Lawrence C., Wolf, Alex M., Beanan, Maureen J., Brinkac, Lauren M., Daugherty, Sean C., DeBoy, Robert T., Durkin, A. Scott, Kolonay, James F., Madupu, Ramana, Lewis, Matthew R., Radune, Diana, Fedorova, Nadezhda B., Scanlan, David, Khouri, Hoda, Mulligan, Stephanie, Carty, Heather A., Cline, Robin T., Van Aken, Susan E., Gill, John, Scarselli, Maria, Mora, Marirosa, Iacobini, Emilia T., Brettoni, Cecilia, Galli, Giuliano, Mariani, Massimo, Vegni, Filippo, Maione, Domenico, Rinaudo, Daniela, Rappuoli, Rino, Telford, John L., Kasper, Dennis L., Grandi, Guido, and Fraser, Claire M.

Published
2002

6. Immune responses to invasive group B streptococcal disease in adults

Author

Edwards, Morven S., Rench, Marcia A., Rinaudo, Daniela, Fabbrini, Monica, Tuscano, Giovanna, Buffi, Giada, Bartolini, Erika, Bonacci, Stefano, Baker, Carol J., and Margarit, Immaculada

Subjects
Immune response -- Testing, Streptococcal infections -- Development and progression, Health
Abstract

In the United States, group B Streptococcus (GBS) has emerged as a frequent cause of invasive infection in nonpregnant adults with underlying medical conditions. The incidence of GBS disease among [...]

Published
2016
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7. Neonatal invasive disease caused by Streptococcus agalactiae in Europe: the DEVANI multi-center study

Author

Lohrmann, Florens, primary, Hufnagel, Markus, additional, Kunze, Mirjam, additional, Afshar, Baharak, additional, Creti, Roberta, additional, Detcheva, Antoaneta, additional, Kazakova, Jana, additional, Rodriguez-Granger, Javier, additional, Sørensen, Uffe B. Skov, additional, Margarit, Immaculada, additional, Maione, Domenico, additional, Rinaudo, Daniela, additional, Orefici, Graziella, additional, Kilian, Mogens, additional, Efstratiou, Androulla, additional, Berner, Reinhard, additional, and Melin, Pierrette, additional

Published
2022
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10. Augmented reality as means to communicate building heritage data in urban setting

Author

Moglia, Giuseppe, Osello, Anna, Macii, Enrico, PATRIZIA LOMBARDI, Acquaviva, Andrea, Alberto, Brunatto, Erba, David, Edoardo Patti, Rinaudo, Daniela, Francesca Maria Ugliotti, MOGLIA, Giuseppe, OSELLO, Anna, MACII, Enrico, LOMBARDI, PATRIZIA, ACQUAVIVA, ANDREA, Alberto Brunatto, ERBA, DAVID, PATTI, EDOARDO, RINAUDO, DANIELA, and UGLIOTTI, FRANCESCA MARIA

Subjects
survey, BIM, Interoperability, augmented reality
Abstract

Today, augmented and virtual reality represent a new method of communication, offering various opportunities for renewal in the field of architectural and urban scale representation. Contextually to the European project SEEMPubS (Smart Energy Efficient Middleware for Public Space), some innovative methods for project data dissemination have been tried, including an Android app and some playful activities, designed to increase user awareness on energy saving theme.

Published
2013

11. Genomic analysis reveals the molecular basis for capsule loss in the group B Streptococcus population

Author

Rosini, Roberto, Campisi, Edmondo, De Chiara, Matteo, Tettelin, Hervé, Rinaudo, Daniela, Toniolo, Chiara, Metruccio, Matteo, Guidotti, Silvia, Skov Sørensen, Uffe B., Kilian, Mogens, Ramirez, Mario, Janulczyk, Robert, Donati, Claudio, Grandi, Guido, Margarit, Immaculada, Melin, P., Decheva, A., Petrunov, B., Kriz, P., Berner, R., Hufnagel, M., Kunze, M., Creti, R., Baldassarri, L., Berardi, A., Orefici, G., Granger, J. R., De La Rosa Fraile, M., Afshar, B., Efstratiou, A., Maione, D., and Telford, J. L.

Subjects
Bacterial capsule, Genetics and Molecular Biology (all), Evoluzione del genoma, lcsh:Medicine, Evolutionary biology, medicine.disease_cause, Genome, Biochemistry, lcsh:Science, Mastitis, Bovine, Genetics, 0303 health sciences, education.field_of_study, Multidisciplinary, Medicine (all), Genomics, Stop codon, 3. Good health, Complementation, Female, Genomica, Research Article, DNA, Bacterial, Settore BIO/18 - GENETICA, Population, Biology, Polymorphism, Single Nucleotide, Microbiology, Streptococcus agalactiae, 03 medical and health sciences, Bacterial Proteins, Streptococcal Infections, medicine, Animals, Humans, Agricultural and Biological Sciences (all), Biochemistry, Genetics and Molecular Biology (all), education, Gene, Bacterial Capsules, 030304 developmental biology, Base Sequence, Cattle, Multilocus Sequence Typing, Sequence Alignment, Sequence Analysis, DNA, 030306 microbiology, Point mutation, lcsh:R, lcsh:Q
Abstract

The human and bovine bacterial pathogen Streptococcus agalactiae (Group B Streptococcus, GBS) expresses a thick polysaccharide capsule that constitutes a major virulence factor and vaccine target. GBS can be classified into ten distinct serotypes differing in the chemical composition of their capsular polysaccharide. However, non-typeable strains that do not react with anti-capsular sera are frequently isolated from colonized and infected humans and cattle. To gain a comprehensive insight into the molecular basis for the loss of capsule expression in GBS, a collection of well-characterized non-typeable strains was investigated by genome sequencing. Genome based phylogenetic analysis extended to a wide population of sequenced strains confirmed the recently observed high clonality among GBS lineages mainly containing human strains, and revealed a much higher degree of diversity in the bovine population. Remarkably, non-typeable strains were equally distributed in all lineages. A number of distinct mutations in the cps operon were identified that were apparently responsible for inactivation of capsule synthesis. The most frequent genetic alterations were point mutations leading to stop codons in the cps genes, and the main target was found to be cpsE encoding the portal glycosyl trasferase of capsule biosynthesis. Complementation of strains carrying missense mutations in cpsE with a wild-type gene restored capsule expression allowing the identification of amino acid residues essential for enzyme activity.

Published
2015
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12. Structural and functional characterization of Group B Streptococcus pilus 2b

Author

Rinaudo, Daniela, Lazzarin, Maddalena <1986>, Rinaudo, Daniela, and Lazzarin, Maddalena <1986>

Abstract

Group B Streptococcus (GBS) is a Gram-positive human pathogen representing one of the most common causes of life-threatening bacterial infections such as sepsis and meningitis in neonates. Covalently polymerized pilus-like structures have been discovered in GBS as important virulence factors as well as vaccine candidates. Pili are protein polymers forming long and thin filamentous structures protruding from bacterial cells, mediating adhesion and colonization to host cells. Gram-positive bacteria, including GBS, build pili on their cell surface via a class C sortase-catalyzed transpeptidation mechanism from pilin protein substrates that are the backbone protein forming the pilus shaft and two ancillary proteins. Also the cell-wall anchoring of the pilus polymers made of covalently linked pilin subunits is mediated by a sortase enzyme. GBS expresses three structurally distinct pilus types (type 1, 2a and 2b). Although the mechanisms of assembly and cell wall anchoring of GBS types 1 and 2a pili have been investigated, those of pilus 2b are not understood until now. Pilus 2b is frequently found in ST-17 strains that are mostly associated with meningitis and high mortality rate especially in infants. In this work the assembly mechanism of GBS pilus type 2b has been elucidated by dissecting through genetic, biochemical and structural studies the role of the two pilus-associated sortases. The most significant findings show that pilus 2b assembly appears “non-canonical”, differing significantly from current pilus assembly models in Gram-positive pathogens. Only sortase-C1 is involved in pilin polymerization, while the sortase-C2 does not act as a pilin polymerase, but it is involved in cell-wall pilus anchoring. Our findings provide new insights into pili biogenesis in Gram-positive bacteria. Moreover, the role of this pilus type during host infection has been investigated. By using a mouse model of meningitis we demonstrated that type 2b pilus contributes to pathogenesis

Published
2015

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