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1. Effects of oxygen on the response of mitochondria to X-irradiation and reactive oxygen species-mediated fibroblast activation

Author

Tsutomu Shimura, Rina Totani, Hyougo Ogasawara, Keiki Inomata, Megumi Sasatani, Kenji Kamiya, and Akira Ushiyama

Subjects
Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging
Abstract

In living organisms, sensitivity to radiation increases in the presence of oxygen (OOInduction of DNA damage (marker: γ-H2A histone family member X) and mitochondrial signaling (AMP-activated protein kinase), suppression of mitochondrial metabolic activity, and generation of reactive oxygen species occurred with radiation in cells cultured under 5% and 20% OO

Published
2022
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