14 results on '"Riju Banerjee"'
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2. Strain Modulated Superlattices in Graphene
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Eric Hudson, Aurélien Lherbier, Lavish Pabbi, Viet-Hung Nguyen, Mauricio Terrones, Anna Binion, Jean-Christophe Charlier, Tomotaroh Granzier-Nakajima, Riju Banerjee, and UCL - SST/IMCN/MODL - Modelling more...
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Length scale ,Condensed Matter - Materials Science ,Materials science ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed matter physics ,Graphene ,Mechanical Engineering ,Superlattice ,Materials Science (cond-mat.mtrl-sci) ,FOS: Physical sciences ,Bioengineering ,Heterojunction ,02 engineering and technology ,General Chemistry ,Landau quantization ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,law.invention ,Wavelength ,Quantization (physics) ,law ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,General Materials Science ,Scanning tunneling microscope ,0210 nano-technology - Abstract
Strain engineering of graphene takes advantage of one of the most dramatic responses of Dirac electrons enabling their manipulation via strain-induced pseudo-magnetic fields. Numerous theoretically proposed devices, such as resonant cavities and valley filters, as well as novel phenomena, such as snake states, could potentially be enabled via this effect. These proposals, however, require strong, spatially oscillating magnetic fields while to date only the generation and effects of pseudo-gauge fields which vary at a length scale much larger than the magnetic length have been reported. Here we create a periodic pseudo-gauge field profile using periodic strain that varies at the length scale comparable to the magnetic length and study its effects on Dirac electrons. A periodic strain profile is achieved by pulling on graphene with extreme (>10%) strain and forming nanoscale ripples, akin to a plastic wrap pulled taut at its edges. Combining scanning tunneling microscopy and atomistic calculations, we find that spatially oscillating strain results in a new quantization different from the familiar Landau quantization observed in previous studies. We also find that graphene ripples are characterized by large variations in carbon-carbon bond length, directly impacting the electronic coupling between atoms, which within a single ripple can be as different as in two different materials. The result is a single graphene sheet that effectively acts as an electronic superlattice. Our results thus also establish a novel approach to synthesize an effective 2D lateral heterostructure - by periodic modulation of lattice strain., 18 pages, 5 figures and supplementary information more...
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- 2020
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3. Is our initial evaluation of patients admitted for syncope guideline-directed and cost-effective?
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James Desemone, Muhammad Hamza Saad Shaukat, Radmila Lyubarova, Riju Banerjee, and Muhammad Asim Shabbir
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medicine.medical_specialty ,biology ,Guideline adherence ,Cost effectiveness ,business.industry ,Syncope (genus) ,Emergency department ,Guideline ,030204 cardiovascular system & hematology ,biology.organism_classification ,Syncope ,03 medical and health sciences ,Orthostatic vital signs ,0302 clinical medicine ,Emergency medicine ,medicine ,Orthostatic blood pressure ,In patient ,Cost-effectiveness ,030212 general & internal medicine ,Audit / Quality Improvement ,Cardiology and Cardiovascular Medicine ,business - Abstract
IntroductionRecent American College of Cardiology and European Society of Cardiology guidelines for syncope evaluation help distinguish high-cardiac risk patients from those with low-risk orthostatic and neurogenic syncope. Inpatient evaluation is recommended if at least one high-risk feature is present.ObjectiveTo assess guideline adherence and its impact on hospitalization in patients who presented with syncope before and after the introduction of guideline-based syncope protocol in the emergency department (ED).MethodsAll adult patients admitted to general medicine from the ED with the primary diagnosis of syncope in the months of October 2016 and October 2018 (before and after the introduction of syncope protocol in 2017). Electronic charts were retrospectively reviewed for high-risk cardiac features and orthostatic blood pressure measurement.ResultsSixty patients were admitted for syncope in October 2016 (n = 32) and October 2018 (n = 28), out of which 33 (55%) were female and 47 (78.3%) were over age 50. Forty-five patients had at least one high-risk feature. Excluding one patient with an alternate diagnosis at discharge, 14 out of 60 patients (23.3%) admitted for syncope did not have any high-risk feature. Orthostatic blood pressure was measured in 3 patients (5%) in the ED and 27 patients (45%) later in the hospitalization. Six out of eight patients with implanted cardioverter-defibrillator or pacemaker had their devices interrogated. After the introduction of syncope protocol, there was an improvement in the proportion of high-risk patients admitted [68.7% (22/32) in October 2016 vs. 82.1% (23/28) in October 2018].ConclusionUtilizing syncope protocol in the ED may improve guideline adherence, direct appropriate disposition, and reduce healthcare expenses. more...
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- 2020
4. A NAVAL QUANDARY: A RARE CASE OF FASICULOVENTRICULAR PREEXCITATION
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Riju Banerjee and Evan Adelstein
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medicine.medical_specialty ,business.industry ,General surgery ,Rare case ,Medicine ,Cardiology and Cardiovascular Medicine ,business - Published
- 2021
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5. FULMINANT MYOCARDITIS SECONDARY TO H1N1 INFLUENZA TYPE A IN A HEALTHY ADULT LEADING TO CARDIOGENIC SHOCK REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION WITH COMPLETE RECOVERY
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Sulagna Mookherjee, Sheikh Raza Shahzad, Riju Banerjee, and Usman Naseer
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Myocarditis ,business.industry ,Fulminant ,medicine.medical_treatment ,Cardiogenic shock ,H1N1 influenza ,Critical Care and Intensive Care Medicine ,medicine.disease ,Internal medicine ,medicine ,Extracorporeal membrane oxygenation ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Published
- 2020
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6. Coronary Revascularization in High-Risk Stable Patients With Significant Comorbidities: Challenges in Decision-Making
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Kellsey A. Peterson, Riju Banerjee, Sanjay Samy, Joshua Schulman-Marcus, and Neil Yager
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medicine.medical_specialty ,education.field_of_study ,business.industry ,medicine.medical_treatment ,Population ,Percutaneous coronary intervention ,Disease ,030204 cardiovascular system & hematology ,Revascularization ,medicine.disease ,Comorbidity ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Conventional PCI ,Cohort ,Medicine ,030212 general & internal medicine ,Cardiology and Cardiovascular Medicine ,business ,Intensive care medicine ,education - Abstract
There is a growing cohort of complex high-risk patients with stable ischemic heart disease (SIHD) who present for coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI). These patients are older, have complex coronary disease, and a substantial comorbidity burden including frailty. The procedural risks and outcomes of CABG and PCI in these patients are more difficult to assess based on the available literature, which has generally studied a younger population with a lower comorbidity burden. There have been initiatives to recalibrate and expand risk models derived from procedural registries to inform the care of complex higher-risk patients, including patients “turned down” for CABG. There is greater recognition of the need for improved assessment of risk, quality, and benefits of coronary revascularization in higher-risk SIHD patients with a substantial comorbidity burden. Clinicians and patients should be aware that there are significant evidence gaps regarding revascularization in complex high-risk patients. The limitations of procedural-derived risk scores should be understood when presenting treatment options. Future randomized controlled trials and expanded registries are greatly desired and should be achievable. Meanwhile, a multidisciplinary heart team approach should be employed for proper decision-making. more...
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- 2019
7. PERICARDIAL LIPOMA PRESENTING AS UNSTABLE ANGINA
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Sanjay A Samy, William Alderisio, Riju Banerjee, Neil Yager, Stacey L. Langford, Jacqueline Kenitz, and Joshua Schulman-Marcus
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medicine.medical_specialty ,business.industry ,Unstable angina ,Internal medicine ,Cardiology ,Medicine ,Lipoma ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Published
- 2020
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8. EHBP-1 Functions with RAB-10 during Endocytic Recycling inCaenorhabditis elegans
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Riju Banerjee, Christopher Rongo, Barth D. Grant, Carlos Chih Hsiung Chen, Anjon Audhya, Anbing Shi, and Doreen R. Glodowski
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Endosome ,Green Fluorescent Proteins ,Molecular Sequence Data ,Endocytic cycle ,Vesicular Transport Proteins ,Endocytic recycling ,Endosomes ,Biology ,Calponin homology domain ,03 medical and health sciences ,Adenosine Triphosphate ,Two-Hybrid System Techniques ,Animals ,Amino Acid Sequence ,Receptors, AMPA ,Caenorhabditis elegans ,Caenorhabditis elegans Proteins ,Molecular Biology ,030304 developmental biology ,0303 health sciences ,Sequence Homology, Amino Acid ,fungi ,030302 biochemistry & molecular biology ,Articles ,Cell Biology ,biology.organism_classification ,Endocytosis ,Transport protein ,Cell biology ,Protein Transport ,Microscopy, Fluorescence ,Membrane Trafficking ,rab GTP-Binding Proteins ,RNA Interference ,Rab ,Protein Binding - Abstract
Caenorhabditis elegans RAB-10 functions in endocytic recycling in polarized cells, regulating basolateral cargo transport in the intestinal epithelia and postsynaptic cargo transport in interneurons. Here we show binding of RAB-10 to EHBP-1, a CH-domain protein, and demonstrate a requirement for EHBP-1 in RAB-10–regulated transport in both of these tissues., Caenorhabditis elegans RAB-10 functions in endocytic recycling in polarized cells, regulating basolateral cargo transport in the intestinal epithelia and postsynaptic cargo transport in interneurons. A similar role was found for mammalian Rab10 in MDCK cells, suggesting that a conserved mechanism regulates these related pathways in metazoans. In a yeast two-hybrid screen for binding partners of RAB-10 we identified EHBP-1, a calponin homology domain (CH) protein, whose mammalian homolog Ehbp1 was previously shown to function during endocytic transport of GLUT4 in adipocytes. In vivo we find that EHBP-1-GFP colocalizes with RFP-RAB-10 on endosomal structures of the intestine and interneurons and that ehbp-1 loss-of-function mutants share with rab-10 mutants specific endosome morphology and cargo localization defects. We also show that loss of EHBP-1 disrupts transport of membrane proteins to the plasma membrane of the nonpolarized germline cells, a defect that can be phenocopied by codepletion of RAB-10 and its closest paralog RAB-8. These results indicate that RAB-10 and EHBP-1 function together in many cell types and suggests that there are differences in the level of redundancy among Rab family members in polarized versus nonpolarized cells. more...
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- 2010
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9. ANITA—An active vibration cancellation system for scanning probe microscopy
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Anna Binion, Eric Hudson, Bill Dusch, C. B. Shoop, Riju Banerjee, and Lavish Pabbi
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010302 applied physics ,Physics ,Microscope ,Noise (signal processing) ,Acoustics ,Cryocooler ,Accelerometer ,01 natural sciences ,Signal ,law.invention ,Vibration ,Scanning probe microscopy ,law ,0103 physical sciences ,Sensitivity (control systems) ,010306 general physics ,Instrumentation - Abstract
The high sensitivity of scanning probe microscopes poses a barrier to their use in noisy environments. Vibrational noise, whether from structural or acoustic sources, can manifest as relative motion between the probe tip and sample, which then appears in the probe position ("Z") feedback as it tries to cancel this motion. Here we describe an active cancellation process that nullifies the appearance of this vibration by adding a drive signal into the existing Z-feedback loop. The drive is digitally calculated from accelerometer-based vibration measurements. By transferring the vibration cancellation effort to this drive signal, vibration-created noise is significantly reduced. This inexpensive and easy solution requires no major instrumental modifications and is ideal for those looking to place their microscopes in noisier environments, coupled, for example, to active refrigeration systems (e.g., pulse tube cryocoolers) or other high-vibration instruments. more...
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- 2018
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10. Regulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8
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Anbing Shi, Lin Sun, Riju Banerjee, Yinhua Zhang, Michael L. Tobin, and Barth D. Grant
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Retromer ,Endosome ,Vesicular Transport Proteins ,Golgi Apparatus ,Endosomes ,macromolecular substances ,Endocytosis ,Clathrin ,Article ,General Biochemistry, Genetics and Molecular Biology ,Cell Line ,symbols.namesake ,Animals ,Caenorhabditis elegans ,Caenorhabditis elegans Proteins ,Sorting Nexins ,Molecular Biology ,Neurons ,General Immunology and Microbiology ,biology ,General Neuroscience ,Vesicle ,HSC70 Heat-Shock Proteins ,Intracellular Signaling Peptides and Proteins ,Cell Polarity ,Golgi apparatus ,Cell biology ,Retromer complex ,Mutation ,symbols ,biology.protein ,Clathrin adaptor proteins ,Carrier Proteins ,Lysosomes ,Molecular Chaperones - Abstract
After endocytosis, most cargo enters the pleiomorphic early endosomes in which sorting occurs. As endosomes mature, transmembrane cargo can be sequestered into inwardly budding vesicles for degradation, or can exit the endosome in membrane tubules for recycling to the plasma membrane, the recycling endosome, or the Golgi apparatus. Endosome to Golgi transport requires the retromer complex. Without retromer, recycling cargo such as the MIG-14/Wntless protein aberrantly enters the degradative pathway and is depleted from the Golgi. Endosome-associated clathrin also affects the recycling of retrograde cargo and has been shown to function in the formation of endosomal subdomains. Here, we find that the Caemorhabditis elegans endosomal J-domain protein RME-8 associates with the retromer component SNX-1. Loss of SNX-1, RME-8, or the clathrin chaperone Hsc70/HSP-1 leads to over-accumulation of endosomal clathrin, reduced clathrin dynamics, and missorting of MIG-14 to the lysosome. Our results indicate a mechanism, whereby retromer can regulate endosomal clathrin dynamics through RME-8 and Hsc70, promoting the sorting of recycling cargo into the retrograde pathway. more...
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- 2009
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11. COMPARISON OF IN-HOSPITAL OUTCOMES OF SEPTIC SHOCK PATIENTS WITH AND WITHOUT ATRIAL FIBRILLATION: A RETROSPECTIVE PROPENSITY-MATCHED ANALYSIS
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Riju Banerjee, Victor Mazza, Alfonso H. Waller, Marc Klapholz, Osama Tariq Niazi, Ahmad Alkhalil, Shashank Jain, Adebayo Olusanya, Luke Chong, and Shervin Golbari
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medicine.medical_specialty ,Hospital outcomes ,business.industry ,Septic shock ,Propensity score matching ,medicine ,Atrial fibrillation ,Cardiology and Cardiovascular Medicine ,Intensive care medicine ,medicine.disease ,business - Published
- 2017
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12. ACE Inhibitors Improve Outcomes in Percutaneous Infrainguinal Interventions
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Peter L. Faries, Ageliki G. Vouyouka, Riju Banerjee, Daniel Han, Victoria Teodorescu, Robert A. Lookstein, James W. Cornwall, Michael L. Marin, and David L. Ku
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medicine.medical_specialty ,Percutaneous ,business.industry ,Psychological intervention ,medicine ,Surgery ,Intensive care medicine ,business ,Cardiology and Cardiovascular Medicine - Published
- 2013
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13. Atrial fibrillation and mortality in advanced lung cancer patients
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Riju Banerjee, Shashank Jain, Ahmad A. Al Turk, Natalija Odanovic, Steve Tsai, S. Srinivas, Elena Dolmatova, Yulanka Castro, Victor T. Chang, Kasra Moazzami, Eman Rashed, Edward Rojas, Monali Patel, and Njambi Mathenge more...
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Oncology ,Cancer Research ,medicine.medical_specialty ,education.field_of_study ,Lung ,business.industry ,Incidence (epidemiology) ,Population ,Cancer ,Atrial fibrillation ,030204 cardiovascular system & hematology ,Esophageal cancer ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Increased risk ,Internal medicine ,medicine ,Lung cancer ,business ,education ,030217 neurology & neurosurgery - Abstract
e23205Background: The incidence of atrial fibrillation (AF) and cancer are rising as the population ages. An increased risk of new-onset AF has been reported after lung and esophageal cancer surger... more...
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- 2016
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14. RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate
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Riju Banerjee, Carlos Chih Hsiung Chen, Ou Liu, Barth D. Grant, Stefan Eimer, Anbing Shi, and Sabine Koenig
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Phosphatidylinositol 4,5-Diphosphate ,GTPase-activating protein ,Endosome ,Endocytic recycling ,Endosomes ,Biology ,Clathrin ,GTP Phosphohydrolases ,Animals, Genetically Modified ,chemistry.chemical_compound ,Two-Hybrid System Techniques ,Animals ,Caenorhabditis elegans ,Caenorhabditis elegans Proteins ,Multidisciplinary ,Cell Membrane ,GTPase-Activating Proteins ,Membrane transport ,Endocytosis ,Cell biology ,Transport protein ,Protein Structure, Tertiary ,Protein Transport ,Phosphatidylinositol 4,5-bisphosphate ,chemistry ,PNAS Plus ,rab GTP-Binding Proteins ,biology.protein ,Commentary ,Rab - Abstract
Caenorhabditis elegans RAB-10 and mammalian Rab10 are key regulators of endocytic recycling, especially in the basolateral recycling pathways of polarized epithelial cells. To understand better how RAB-10 contributes to recycling endosome function, we sought to identify RAB-10 effectors. One RAB-10-binding partner that we identified, CNT-1, is the only C. elegans homolog of the mammalian Arf6 GTPase-activating proteins ACAP1 and ACAP2. Arf6 is known to regulate endosome-to-plasma membrane transport, in part through activation of type I phophatidylinositol-4-phosphate 5 kinase. Here we show that CNT-1 binds to RAB-10 through its C-terminal ankyrin repeats and colocalizes with RAB-10 and ARF-6 on recycling endosomes in vivo. Furthermore, we find that RAB-10 is required for the recruitment of CNT-1 to endosomal membranes in the intestinal epithelium. Consistent with negative regulation of ARF-6 by RAB-10 and CNT-1, we found overaccumulation of endosomal phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] in cnt-1 and rab-10 mutants and reduced endosomal PI(4,5)P2 levels in arf-6 mutants. These mutants produced similar effects on endosomal recruitment of the PI(4,5)P2-dependent membrane-bending proteins RME-1/Ehd and SDPN-1/Syndapin/Pacsin and resulted in endosomal trapping of specific recycling cargo. Our studies identify a RAB-10–to–ARF-6 regulatory loop required to regulate endosomal PI(4,5)P2, a key phosphoinositide in membrane traffic. more...
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- 2012
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