Search

Your search keyword '"Riisnaes, Ruth"' showing total 433 results
Start Over Author "Riisnaes, Ruth"
433 results on '"Riisnaes, Ruth"'

1. Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance

Author

Guo, Christina, Sharp, Adam, Gurel, Bora, Crespo, Mateus, Figueiredo, Ines, Jain, Suneil, Vogl, Ursula, Rekowski, Jan, Rouhifard, Mahtab, Gallagher, Lewis, Yuan, Wei, Carreira, Suzanne, Chandran, Khobe, Paschalis, Alec, Colombo, Ilaria, Stathis, Anastasios, Bertan, Claudia, Seed, George, Goodall, Jane, Raynaud, Florence, Ruddle, Ruth, Swales, Karen E., Malia, Jason, Bogdan, Denisa, Tiu, Crescens, Caldwell, Reece, Aversa, Caterina, Ferreira, Ana, Neeb, Antje, Tunariu, Nina, Westaby, Daniel, Carmichael, Juliet, Fenor de la Maza, Maria Dolores, Yap, Christina, Matthews, Ruth, Badham, Hannah, Prout, Toby, Turner, Alison, Parmar, Mona, Tovey, Holly, Riisnaes, Ruth, Flohr, Penny, Gil, Jesus, Waugh, David, Decordova, Shaun, Schlag, Anna, Calì, Bianca, Alimonti, Andrea, and de Bono, Johann S.

Published
2023
Full Text
View/download PDF

2. Capivasertib in combination with enzalutamide for metastatic castration resistant prostate cancer after docetaxel and abiraterone: Results from the randomized phase II RE-AKT trial

Author

Rescigno, Pasquale, Porta, Nuria, Finneran, Laura, Riisnaes, Ruth, Figueiredo, Ines, Carreira, Suzanne, Flohr, Penny, Miranda, Susana, Bertan, Claudia, Ferreira, Ana, Crespo, Mateus, Rodrigues, Daniel Nava, Gurel, Bora, Nobes, Jenny, Crabb, Simon, Malik, Zafar, Ralph, Christy, McGovern, Ursula, Hoskin, Peter, Jones, Robert J., Birtle, Alison, Gale, Joanna, Sankey, Peter, Jain, Suneil, McLaren, Duncan, Chadwick, Eliot, Espinasse, Aude, Hall, Emma, and de Bono, Johann

Published
2024
Full Text
View/download PDF

3. Development and Validation of a New BAG-1L–Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer

Author

Neeb, Antje, Figueiredo, Ines, Gurel, Bora, Nava Rodrigues, Daniel, Rekowski, Jan, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, Crespo, Mateus, Westaby, Daniel, de Los Dolores Fenor de La Maza, Maria, Guo, Christina, Carmichael, Juliet, Grochot, Rafael, Tunariu, Nina, Cato, Andrew C.B., Plymate, Stephen R., de Bono, Johann S., and Sharp, Adam

Published
2023
Full Text
View/download PDF

5. B7-H3 as a Therapeutic Target in Advanced Prostate Cancer

Author

Guo, Christina, Figueiredo, Ines, Gurel, Bora, Neeb, Antje, Seed, George, Crespo, Mateus, Carreira, Suzanne, Rekowski, Jan, Buroni, Lorenzo, Welti, Jon, Bogdan, Denisa, Gallagher, Lewis, Sharp, Adam, Fenor de la Maza, Maria D., Rescigno, Pasquale, Westaby, Daniel, Chandran, Khobe, Riisnaes, Ruth, Ferreira, Ana, Miranda, Susana, Calì, Bianca, Alimonti, Andrea, Bressan, Silvia, Nguyen, Alana H.T., Shen, Michael M., Hawley, Jessica E., Obradovic, Aleksandar, Drake, Charles G., Bertan, Claudia, Baker, Chloe, Tunariu, Nina, Yuan, Wei, and de Bono, Johann S.

Published
2023
Full Text
View/download PDF

6. Supplementary Figure 7 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

7. Supplementary Figure 12 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

8. Data from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

9. Supplementary Figure 3 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

10. Supplementary Figure 2 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

11. Supplementary Table 5 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

12. Supplementary Figure 9 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

13. RNASEH2B loss and PARP inhibition in advanced prostate cancer

Author

Carmichael, Juliet, primary, Figueiredo, Ines, additional, Gurel, Bora, additional, Beije, Nick, additional, Yuan, Wei, additional, Rekowski, Jan, additional, Seed, George, additional, Carreira, Suzanne, additional, Bertan, Claudia, additional, Fenor de la Maza, Maria de Los Dolores, additional, Chandran, Khobe, additional, Neeb, Antje, additional, Welti, Jon, additional, Gallagher, Lewis, additional, Bogdan, Denisa, additional, Crespo, Mateus, additional, Riisnaes, Ruth, additional, Ferreira, Ana, additional, Miranda, Susana, additional, Lu, Jinqiu, additional, Shen, Michael M., additional, Hall, Emma, additional, Porta, Nuria, additional, Westaby, Daniel, additional, Guo, Christina, additional, Grochot, Rafael, additional, Lord, Christopher J., additional, Mateo, Joaquin, additional, Sharp, Adam, additional, and de Bono, Johann, additional

Published
2024
Full Text
View/download PDF

14. Supplementary Table 6 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

15. Supplementary Table 1 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

16. Supplementary Table 3 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

17. Supplementary Figure 8 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

18. Supplementary Materials and Methods from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

19. Supplementary Figure 5 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

20. Supplementary Figure 6 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

21. Supplementary Table 7 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

22. Supplementary Table 4 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

23. Supplementary Table 2 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

24. Supplementary Figure 4 from Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer

Author

Neeb, Antje, primary, Figueiredo, Ines, primary, Bogdan, Denisa, primary, Cato, Laura, primary, Stober, Jutta, primary, Jiménez-Vacas, Juan M., primary, Gourain, Victor, primary, Lee, Irene I., primary, Seeger, Rebecca, primary, Muhle-Goll, Claudia, primary, Gurel, Bora, primary, Welti, Jonathan, primary, Nava Rodrigues, Daniel, primary, Rekowski, Jan, primary, Qiu, Xintao, primary, Jiang, Yija, primary, Di Micco, Patrizio, primary, Mateos, Borja, primary, Bielskutė, Stasė, primary, Riisnaes, Ruth, primary, Ferreira, Ana, primary, Miranda, Susana, primary, Crespo, Mateus, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Bräse, Stefan, primary, Jung, Nicole, primary, Gräßle, Simone, primary, Swain, Amanda, primary, Salvatella, Xavier, primary, Plymate, Stephen R., primary, Al-Lazikani, Bissan, primary, Long, Henry W., primary, Yuan, Wei, primary, Brown, Myles, primary, Cato, Andrew C.B., primary, de Bono, Johann S., primary, and Sharp, Adam, primary

Published
2024
Full Text
View/download PDF

25. Immune Biomarkers in Metastatic Castration-resistant Prostate Cancer

Author

Fenor de la Maza, María Dolores, Chandran, Khobe, Rekowski, Jan, Shui, Irene M., Gurel, Bora, Cross, Emily, Carreira, Suzanne, Yuan, Wei, Westaby, Daniel, Miranda, Susana, Ferreira, Ana, Seed, George, Crespo, Mateus, Figueiredo, Ines, Bertan, Claudia, Gil, Veronica, Riisnaes, Ruth, Sharp, Adam, Rodrigues, Daniel Nava, Rescigno, Pasquale, Tunariu, Nina, Liu, Xiao Qiao, Cristescu, Razvan, Schloss, Charles, Yap, Christina, and de Bono, Johann S.

Published
2022
Full Text
View/download PDF

26. BCL2 expression is enriched in androgen receptor-negative advanced prostate cancer

Author

Jimenez-Vacas, Juan M, primary, Westaby, Daniel, additional, Figueiredo, Ines, additional, Rekowski, Jan, additional, Pettinger, Claire, additional, Gurel, Bora, additional, Bogdan, Denisa, additional, Buroni, Lorenzo, additional, Neeb, Antje, additional, Padilha, Ana, additional, Taylor, Joe, additional, Zeng, Wanting, additional, Das, Souvik, additional, Hobern, Emily, additional, Riisnaes, Ruth, additional, Crespo, Mateus, additional, Miranda, Susana, additional, Ferreira, Ana, additional, Hanratty, Brian, additional, Nava, Rodrigues Daniel, additional, Bertan, Claudia, additional, Seed, George, additional, Fenor, de La Maza Maria de Los Dolores, additional, Guo, Christina, additional, Carmichael, Juliet, additional, Grochot, Rafael, additional, Chandran, Khobe, additional, Stavridi, Anastasia, additional, Varkaris, Andreas, additional, Stylianou, Nataly, additional, Hollier, Brett, additional, Tunariu, Nina, additional, Balk, Steven, additional, Carreira, Suzanne, additional, Yuan, Wei, additional, Nelson, Peter, additional, Corey, Eva, additional, Haffner, Michael, additional, de, Bono Johann, additional, and Sharp, Adam, additional

Published
2024
Full Text
View/download PDF

28. Intermittent schedules of the oral RAF–MEK inhibitor CH5126766/VS-6766 in patients with RAS/RAF-mutant solid tumours and multiple myeloma: a single-centre, open-label, phase 1 dose-escalation and basket dose-expansion study

Author

Guo, Christina, Chénard-Poirier, Maxime, Roda, Desamparados, de Miguel, Maria, Harris, Samuel J, Candilejo, Irene Moreno, Sriskandarajah, Priya, Xu, Wen, Scaranti, Mariana, Constantinidou, Anastasia, King, Jenny, Parmar, Mona, Turner, Alison J, Carreira, Suzanne, Riisnaes, Ruth, Finneran, Laura, Hall, Emma, Ishikawa, Yuji, Nakai, Kiyohiko, Tunariu, Nina, Basu, Bristi, Kaiser, Martin, Lopez, Juanita Suzanne, Minchom, Anna, de Bono, Johann S, and Banerji, Udai

Published
2020
Full Text
View/download PDF

29. Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

Author

Mateo, Joaquin, Porta, Nuria, Bianchini, Diletta, McGovern, Ursula, Elliott, Tony, Jones, Robert, Syndikus, Isabel, Ralph, Christy, Jain, Suneil, Varughese, Mohini, Parikh, Omi, Crabb, Simon, Robinson, Angus, McLaren, Duncan, Birtle, Alison, Tanguay, Jacob, Miranda, Susana, Figueiredo, Ines, Seed, George, Bertan, Claudia, Flohr, Penny, Ebbs, Berni, Rescigno, Pasquale, Fowler, Gemma, Ferreira, Ana, Riisnaes, Ruth, Pereira, Rita, Curcean, Andra, Chandler, Robert, Clarke, Matthew, Gurel, Bora, Crespo, Mateus, Nava Rodrigues, Daniel, Sandhu, Shahneen, Espinasse, Aude, Chatfield, Peter, Tunariu, Nina, Yuan, Wei, Hall, Emma, Carreira, Suzanne, and de Bono, Johann S

Published
2020
Full Text
View/download PDF

30. Thio-2 inhibits key signaling pathways required for the development and progression of castration resistant prostate cancer.

Author

Neeb, Antje, primary, Figueiredo, Ines, additional, Bogdan, Denisa, additional, Cato, Laura, additional, Stober, Jutta, additional, Jiménez-Vacas, Juan M., additional, Gourain, Victor, additional, Lee, Irene I., additional, Seeger, Rebecca, additional, Muhle-Goll, Claudia, additional, Gurel, Bora, additional, Welti, Jonathan, additional, Nava Rodrigues, Daniel, additional, Rekowski, Jan, additional, Qiu, Xintao, additional, Jiang, Yija, additional, Di Micco, Patrizio, additional, Mateos, Borja, additional, Bielskutė, Stasė, additional, Riisnaes, Ruth, additional, Ferreira, Ana, additional, Miranda, Susana, additional, Crespo, Mateus, additional, Buroni, Lorenzo, additional, Ning, Jian, additional, Carreira, Suzanne, additional, Bräse, Stefan, additional, Jung, Nicole, additional, Gräßle, Simone, additional, Swain, Amanda, additional, Salvatella, Xavier, additional, Plymate, Stephen R., additional, Al-Lazikani, Bissan, additional, Long, Henry W., additional, Yuan, Wei, additional, Brown, Myles, additional, Cato, Andrew C.B., additional, de Bono, Johann S., additional, and Sharp, Adam, additional

Published
2024
Full Text
View/download PDF

31. Supplementary Figure S3 from Olaparib and Ceralasertib (AZD6738) in Patients with Triple-Negative Advanced Breast Cancer: Results from Cohort E of the plasmaMATCH Trial (CRUK/15/010)

Author

Ring, Alistair, primary, Kilburn, Lucy S., primary, Pearson, Alex, primary, Moretti, Laura, primary, Afshari-Mehr, Angelica, primary, Wardley, Andrew M., primary, Gurel, Bora, primary, Macpherson, Iain R., primary, Riisnaes, Ruth, primary, Baird, Richard D., primary, Martin, Sue, primary, Roylance, Rebecca, primary, Johnson, Hannah, primary, Ferreira, Ana, primary, Winter, Matthew C., primary, Dunne, Kathryn, primary, Copson, Ellen, primary, Hickish, Tamas, primary, Burcombe, Russell, primary, Randle, Kat, primary, Serra, Violeta, primary, Llop-Guevara, Alba, primary, Bliss, Judith M., primary, and Turner, Nicolas C., primary

Published
2023
Full Text
View/download PDF

32. DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

Author

Mateo, Joaquin, Carreira, Suzanne, Sandhu, Shahneen, Miranda, Susana, Mossop, Helen, Perez-Lopez, Raquel, Nava Rodrigues, Daniel, Robinson, Dan, Omlin, Aurelius, Tunariu, Nina, Boysen, Gunther, Porta, Nuria, Flohr, Penny, Gillman, Alexa, Figueiredo, Ines, Paulding, Claire, Seed, George, Jain, Suneil, Ralph, Christy, Protheroe, Andrew, Hussain, Syed, Jones, Robert, Elliott, Tony, McGovern, Ursula, Bianchini, Diletta, Goodall, Jane, Zafeiriou, Zafeiris, Williamson, Chris T, Ferraldeschi, Roberta, Riisnaes, Ruth, Ebbs, Bernardette, Fowler, Gemma, Roda, Desamparados, Yuan, Wei, Wu, Yi-Mi, Cao, Xuhong, Brough, Rachel, Pemberton, Helen, A'Hern, Roger, Swain, Amanda, Kunju, Lakshmi P, Eeles, Rosalind, Attard, Gerhardt, Lord, Christopher J, Ashworth, Alan, Rubin, Mark A, Knudsen, Karen E, Feng, Felix Y, Chinnaiyan, Arul M, Hall, Emma, and de Bono, Johann S

Subjects
Genetics, Urologic Diseases, Human Genome, Prostate Cancer, Cancer, Clinical Research, 6.1 Pharmaceuticals, 6.2 Cellular and gene therapies, Evaluation of treatments and therapeutic interventions, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, Adult, Aged, Anemia, Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, DNA Repair, Drug Resistance, Neoplasm, Enzyme Inhibitors, Fatigue, Genes, BRCA2, Genes, Tumor Suppressor, Humans, Male, Middle Aged, Mutation, Neoplasm Metastasis, Phthalazines, Piperazines, Poly(ADP-ribose) Polymerase Inhibitors, Prostatic Neoplasms, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundProstate cancer is a heterogeneous disease, but current treatments are not based on molecular stratification. We hypothesized that metastatic, castration-resistant prostate cancers with DNA-repair defects would respond to poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibition with olaparib.MethodsWe conducted a phase 2 trial in which patients with metastatic, castration-resistant prostate cancer were treated with olaparib tablets at a dose of 400 mg twice a day. The primary end point was the response rate, defined either as an objective response according to Response Evaluation Criteria in Solid Tumors, version 1.1, or as a reduction of at least 50% in the prostate-specific antigen level or a confirmed reduction in the circulating tumor-cell count from 5 or more cells per 7.5 ml of blood to less than 5 cells per 7.5 ml. Targeted next-generation sequencing, exome and transcriptome analysis, and digital polymerase-chain-reaction testing were performed on samples from mandated tumor biopsies.ResultsOverall, 50 patients were enrolled; all had received prior treatment with docetaxel, 49 (98%) had received abiraterone or enzalutamide, and 29 (58%) had received cabazitaxel. Sixteen of 49 patients who could be evaluated had a response (33%; 95% confidence interval, 20 to 48), with 12 patients receiving the study treatment for more than 6 months. Next-generation sequencing identified homozygous deletions, deleterious mutations, or both in DNA-repair genes--including BRCA1/2, ATM, Fanconi's anemia genes, and CHEK2--in 16 of 49 patients who could be evaluated (33%). Of these 16 patients, 14 (88%) had a response to olaparib, including all 7 patients with BRCA2 loss (4 with biallelic somatic loss, and 3 with germline mutations) and 4 of 5 with ATM aberrations. The specificity of the biomarker suite was 94%. Anemia (in 10 of the 50 patients [20%]) and fatigue (in 6 [12%]) were the most common grade 3 or 4 adverse events, findings that are consistent with previous studies of olaparib.ConclusionsTreatment with the PARP inhibitor olaparib in patients whose prostate cancers were no longer responding to standard treatments and who had defects in DNA-repair genes led to a high response rate. (Funded by Cancer Research UK and others; ClinicalTrials.gov number, NCT01682772; Cancer Research UK number, CRUK/11/029.).

Published
2015

33. 84 Deciphering the immune microenvironment in castration-resistant prostate cancer (CRPC) through hyperplex immunofluorescence and AI-assisted image analysis: Unveiling potential immunotherapy biomarkers

Author

Gurel, Bora, primary, Figueiredo, Ines, additional, Crespo, Mateus, additional, Guo, Christina, additional, Seed, George, additional, Ferreira, Ana, additional, Riisnaes, Ruth, additional, Yuan, Wei, additional, Carreira, Suzanne, additional, and Bono, Johann De, additional

Published
2023
Full Text
View/download PDF

34. Olaparib and celarasertib (AZD6738) in patients with triple negative advanced breast cancer: results from Cohort E of the plasmaMATCH trial (CRUK/15/010)

Author

Ring, Alistair, primary, Kilburn, Lucy S., additional, Pearson, Alex, additional, Moretti, Laura, additional, Afshari-Mehr, Angelica, additional, Wardley, Andrew M., additional, Gurel, Bora, additional, Macpherson, Iain R., additional, Riisnaes, Ruth, additional, Baird, Richard D., additional, Martin, Sue, additional, Roylance, Rebecca, additional, Johnson, Hannah, additional, Ferreira, Ana, additional, Winter, Matthew C., additional, Dunne, Kathryn, additional, Copson, Ellen, additional, Hickish, Tamas, additional, Burcombe, Russell, additional, Randle, Kat, additional, Serra, Violeta, additional, Llop-Guevara, Alba, additional, Bliss, Judith M., additional, and Turner, Nicholas C., additional

Published
2023
Full Text
View/download PDF

35. Docetaxel Treatment in PTEN- and ERG-aberrant Metastatic Prostate Cancers

Author

Rescigno, Pasquale, Lorente, David, Dolling, David, Ferraldeschi, Roberta, Rodrigues, Daniel Nava, Riisnaes, Ruth, Miranda, Susana, Bianchini, Diletta, Zafeiriou, Zafeiris, Sideris, Spyridon, Ferreira, Ana, Figueiredo, Ines, Sumanasuriya, Semini, Mateo, Joaquin, Perez-Lopez, Raquel, Sharp, Adam, Tunariu, Nina, and de Bono, Johann S.

Published
2018
Full Text
View/download PDF

36. Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

Author

Sharp, Adam, Coleman, Ilsa, Yuan, Wei, Sprenger, Cynthia, Dolling, David, Rodrigues, Daniel Nava, Russo, Joshua W., Figueiredo, Ines, Bertan, Claudia, Seed, George, Riisnaes, Ruth, Uo, Takuma, Neeb, Antje, Welti, Jonathan, Morrissey, Colm, Carreira, Suzanne, Luo, Jun, Nelson, Peter S., Balk, Steven P., True, Lawrence D., de Bono, Johann S., and Plymate, Stephen R.

Subjects
Biology -- Usage, Cancer patients -- Health aspects, Gene expression -- Research, Prostate cancer -- Genetic aspects -- Diagnosis -- Development and progression, Health care industry
Abstract

BACKGROUND. Liquid biopsies have demonstrated that the constitutively active androgen receptor splice variant-7 (AR-V7) associates with reduced response and overall survival from endocrine therapies in castration-resistant prostate cancer (CRPC). However, these studies provide little information pertaining to AR-V7 expression in prostate cancer (PC) tissue.METHODS. Following generation and validation of a potentially novel AR-V7 antibody for IHC, AR-V7 protein expression was determined for 358 primary prostate samples and 293 metastatic biopsies. Associations with disease progression, full-length androgen receptor (AR-FL) expression, response to therapy, and gene expression were determined.RESULTS. We demonstrated that AR-V7 protein is rarely expressed (CONCLUSION. This study provides impetus to develop therapies that abrogate AR-V7 signaling to improve our understanding of AR-V7 biology and to confirm the clinical significance of AR-V7.FUNDING. Work at the University of Washington and in the Plymate and Nelson laboratories is supported by the Department of Defense Prostate Cancer Research Program (W81XWH-14-2-0183, W81XWH-12-PCRP-TIA, W81XWH-15-1-0430, and W81XWH-13-2-0070), the Pacific Northwest Prostate Cancer SPORE (P50CA97186), the Institute for Prostate Cancer Research, the Veterans Affairs Research Program, the NIH/National Cancer Institute (P01CA163227), and the Prostate Cancer Foundation. Work in the de Bono laboratory was supported by funding from the Movember Foundation/Prostate Cancer UK (CEO13-2-002), the US Department of Defense (W81XWH-13-2-0093), the Prostate Cancer Foundation (20131017 and 20131017-1), Stand Up To Cancer (SU2C-AACR-DT0712), Cancer Research UK (CRM108X-A25144), and the UK Department of Health through an Experimental Cancer Medicine Centre grant (ECMC-CRM064X)., IntroductionProstate cancer (PC) is the most commonly diagnosed noncutaneous cancer and the second leading cause of male cancer-related death in the Western world (1). Androgen receptor (AR) signaling is critical [...]

Published
2019
Full Text
View/download PDF

37. Erratum to “B7-H3 as a Therapeutic Target in Advanced Prostate Cancer” [Eur Urol 2023;83(3):224–38]

Author

Guo, Christina, primary, Figueiredo, Ines, additional, Gurel, Bora, additional, Neeb, Antje, additional, Seed, George, additional, Crespo, Mateus, additional, Carreira, Suzanne, additional, Rekowski, Jan, additional, Buroni, Lorenzo, additional, Welti, Jon, additional, Bogdan, Denisa, additional, Gallagher, Lewis, additional, Sharp, Adam, additional, de la Maza, Maria D. Fenor, additional, Rescigno, Pasquale, additional, Westaby, Daniel, additional, Chandran, Khobe, additional, Riisnaes, Ruth, additional, Ferreira, Ana, additional, Miranda, Susana, additional, Calì, Bianca, additional, Alimonti, Andrea, additional, Bressan, Silvia, additional, Nguyen, Alana H.T., additional, Shen, Michael M., additional, Hawley, Jessica E., additional, Obradovic, Aleksandar, additional, Drake, Charles G., additional, Bertan, Claudia, additional, Baker, Chloe, additional, Tunariu, Nina, additional, Yuan, Wei, additional, and de Bono, Johann S., additional

Published
2023
Full Text
View/download PDF

38. Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses

Author

Lorente, David, Omlin, Aurelius, Zafeiriou, Zafeiris, Nava-Rodrigues, Daniel, Pérez-López, Raquel, Pezaro, Carmel, Mehra, Niven, Sheridan, Elizabeth, Figueiredo, Ines, Riisnaes, Ruth, Miranda, Susana, Crespo, Mateus, Flohr, Penny, Mateo, Joaquín, Altavilla, Amelia, Ferraldeschi, Roberta, Bianchini, Diletta, Attard, Gerhardt, Tunariu, Nina, and de Bono, Johann

Published
2016
Full Text
View/download PDF

39. Efficacy and Safety of Weekly Paclitaxel Plus Vistusertib vs Paclitaxel Alone in Patients With Platinum-Resistant Ovarian High-Grade Serous Carcinoma

Author

Banerjee, Susana, primary, Giannone, Gaia, additional, Clamp, Andrew R., additional, Ennis, Darren P., additional, Glasspool, Rosalind M., additional, Herbertson, Rebecca, additional, Krell, Jonathan, additional, Riisnaes, Ruth, additional, Mirza, Hasan B., additional, Cheng, Zhao, additional, McDermott, Jacqueline, additional, Green, Clare, additional, Kristeleit, Rebecca S., additional, George, Angela, additional, Gourley, Charlie, additional, Lewsley, Liz-Anne, additional, Rai, Debbie, additional, Banerji, Udai, additional, Hinsley, Samantha, additional, and McNeish, Iain A., additional

Published
2023
Full Text
View/download PDF

40. Abstract CT093: Preliminary evidence of antitumor activity of Ipatasertib (Ipat) and Atezolizumab (A) in glioblastoma (GBM) patients (pts) with PTEN loss in the Phase 1 Ice-CAP trial (NCT03673787)

Author

Tiu, Crescens, primary, Yau, Wing Hing, additional, Welsh, Liam C., additional, Jones, Timothy L., additional, Zachariou, Anna, additional, Prout, Toby, additional, Parmar, Mona, additional, Turner, Alison J., additional, Daly, Robert W., additional, Yap, Christina, additional, Crespo, Mateus, additional, Gurel, Bora, additional, Riisnaes, Ruth M., additional, DeCordova, Shaun A., additional, Swales, Karen E., additional, Banerji, Udai, additional, Minchom, Anna R., additional, Sharp, Adam, additional, de Bono, Johann S., additional, and Lopez, Juanita S., additional

Published
2023
Full Text
View/download PDF

41. Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Author

Gil, Veronica, primary, Miranda, Susana, primary, Riisnaes, Ruth, primary, Gurel, Bora, primary, D’Ambrosio, Mariantonietta, primary, Vasciaveo, Alessandro, primary, Crespo, Mateus, primary, Ferreira, Ana, primary, Brina, Daniela, primary, Troiani, Martina, primary, Sharp, Adam, primary, Sheehan, Beshara, primary, Christova, Rossitza, primary, Seed, George, primary, Figueiredo, Ines, primary, Lambros, Maryou, primary, Dolling, David, primary, Rekowski, Jan, primary, Alajati, Abdullah, primary, Clarke, Matthew, primary, Pereira, Rita, primary, Flohr, Penny, primary, Fowler, Gemma, primary, Boysen, Gunther, primary, Sumanasuriya, Semini, primary, Bianchini, Diletta, primary, Rescigno, Pasquale, primary, Aversa, Caterina, primary, Tunariu, Nina, primary, Guo, Christina, primary, Paschalis, Alec, primary, Bertan, Claudia, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Workman, Paul, primary, Swain, Amanda, primary, Califano, Andrea, primary, Shen, Michael M., primary, Alimonti, Andrea, primary, Neeb, Antje, primary, Welti, Jonathan, primary, Yuan, Wei, primary, and de Bono, Johann, primary

Published
2023
Full Text
View/download PDF

42. Figure S1 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Author

Gil, Veronica, primary, Miranda, Susana, primary, Riisnaes, Ruth, primary, Gurel, Bora, primary, D’Ambrosio, Mariantonietta, primary, Vasciaveo, Alessandro, primary, Crespo, Mateus, primary, Ferreira, Ana, primary, Brina, Daniela, primary, Troiani, Martina, primary, Sharp, Adam, primary, Sheehan, Beshara, primary, Christova, Rossitza, primary, Seed, George, primary, Figueiredo, Ines, primary, Lambros, Maryou, primary, Dolling, David, primary, Rekowski, Jan, primary, Alajati, Abdullah, primary, Clarke, Matthew, primary, Pereira, Rita, primary, Flohr, Penny, primary, Fowler, Gemma, primary, Boysen, Gunther, primary, Sumanasuriya, Semini, primary, Bianchini, Diletta, primary, Rescigno, Pasquale, primary, Aversa, Caterina, primary, Tunariu, Nina, primary, Guo, Christina, primary, Paschalis, Alec, primary, Bertan, Claudia, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Workman, Paul, primary, Swain, Amanda, primary, Califano, Andrea, primary, Shen, Michael M., primary, Alimonti, Andrea, primary, Neeb, Antje, primary, Welti, Jonathan, primary, Yuan, Wei, primary, and de Bono, Johann, primary

Published
2023
Full Text
View/download PDF

43. Supplementary Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Author

Gil, Veronica, primary, Miranda, Susana, primary, Riisnaes, Ruth, primary, Gurel, Bora, primary, D’Ambrosio, Mariantonietta, primary, Vasciaveo, Alessandro, primary, Crespo, Mateus, primary, Ferreira, Ana, primary, Brina, Daniela, primary, Troiani, Martina, primary, Sharp, Adam, primary, Sheehan, Beshara, primary, Christova, Rossitza, primary, Seed, George, primary, Figueiredo, Ines, primary, Lambros, Maryou, primary, Dolling, David, primary, Rekowski, Jan, primary, Alajati, Abdullah, primary, Clarke, Matthew, primary, Pereira, Rita, primary, Flohr, Penny, primary, Fowler, Gemma, primary, Boysen, Gunther, primary, Sumanasuriya, Semini, primary, Bianchini, Diletta, primary, Rescigno, Pasquale, primary, Aversa, Caterina, primary, Tunariu, Nina, primary, Guo, Christina, primary, Paschalis, Alec, primary, Bertan, Claudia, primary, Buroni, Lorenzo, primary, Ning, Jian, primary, Carreira, Suzanne, primary, Workman, Paul, primary, Swain, Amanda, primary, Califano, Andrea, primary, Shen, Michael M., primary, Alimonti, Andrea, primary, Neeb, Antje, primary, Welti, Jonathan, primary, Yuan, Wei, primary, and de Bono, Johann, primary

Published
2023
Full Text
View/download PDF

44. Data from Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition

Author

Goodall, Jane, primary, Mateo, Joaquin, primary, Yuan, Wei, primary, Mossop, Helen, primary, Porta, Nuria, primary, Miranda, Susana, primary, Perez-Lopez, Raquel, primary, Dolling, David, primary, Robinson, Dan R., primary, Sandhu, Shahneen, primary, Fowler, Gemma, primary, Ebbs, Berni, primary, Flohr, Penny, primary, Seed, George, primary, Rodrigues, Daniel Nava, primary, Boysen, Gunther, primary, Bertan, Claudia, primary, Atkin, Mark, primary, Clarke, Matthew, primary, Crespo, Mateus, primary, Figueiredo, Ines, primary, Riisnaes, Ruth, primary, Sumanasuriya, Semini, primary, Rescigno, Pasquale, primary, Zafeiriou, Zafeiris, primary, Sharp, Adam, primary, Tunariu, Nina, primary, Bianchini, Diletta, primary, Gillman, Alexa, primary, Lord, Christopher J., primary, Hall, Emma, primary, Chinnaiyan, Arul M., primary, Carreira, Suzanne, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

45. Data from Targeting the p300/CBP Axis in Lethal Prostate Cancer

Author

Welti, Jonathan, primary, Sharp, Adam, primary, Brooks, Nigel, primary, Yuan, Wei, primary, McNair, Christopher, primary, Chand, Saswati N., primary, Pal, Abhijit, primary, Figueiredo, Ines, primary, Riisnaes, Ruth, primary, Gurel, Bora, primary, Rekowski, Jan, primary, Bogdan, Denisa, primary, West, William, primary, Young, Barbara, primary, Raja, Meera, primary, Prosser, Amy, primary, Lane, Jordan, primary, Thomson, Stuart, primary, Worthington, Jenny, primary, Onions, Stuart, primary, Shannon, Jonathan, primary, Paoletta, Silvia, primary, Brown, Richard, primary, Smyth, Don, primary, Harbottle, Gareth W., primary, Gil, Veronica S., primary, Miranda, Susana, primary, Crespo, Mateus, primary, Ferreira, Ana, primary, Pereira, Rita, primary, Tunariu, Nina, primary, Carreira, Suzanne, primary, Neeb, Antje J., primary, Ning, Jian, primary, Swain, Amanda, primary, Taddei, David, primary, Schiewer, Matthew J., primary, Knudsen, Karen E., primary, Pegg, Neil, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

46. Data from Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2- and Non–BRCA1/2-Mutant Cancers

Author

Yap, Timothy A., primary, Kristeleit, Rebecca, primary, Michalarea, Vasiliki, primary, Pettitt, Stephen J., primary, Lim, Joline S.J., primary, Carreira, Suzanne, primary, Roda, Desamparados, primary, Miller, Rowan, primary, Riisnaes, Ruth, primary, Miranda, Susana, primary, Figueiredo, Ines, primary, Rodrigues, Daniel Nava, primary, Ward, Sarah, primary, Matthews, Ruth, primary, Parmar, Mona, primary, Turner, Alison, primary, Tunariu, Nina, primary, Chopra, Neha, primary, Gevensleben, Heidrun, primary, Turner, Nicholas C., primary, Ruddle, Ruth, primary, Raynaud, Florence I., primary, Decordova, Shaun, primary, Swales, Karen E., primary, Finneran, Laura, primary, Hall, Emma, primary, Rugman, Paul, primary, Lindemann, Justin P.O., primary, Foxley, Andrew, primary, Lord, Christopher J., primary, Banerji, Udai, primary, Plummer, Ruth, primary, Basu, Bristi, primary, Lopez, Juanita S., primary, Drew, Yvette, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

47. Supplementary Data from Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2- and Non–BRCA1/2-Mutant Cancers

Author

Yap, Timothy A., primary, Kristeleit, Rebecca, primary, Michalarea, Vasiliki, primary, Pettitt, Stephen J., primary, Lim, Joline S.J., primary, Carreira, Suzanne, primary, Roda, Desamparados, primary, Miller, Rowan, primary, Riisnaes, Ruth, primary, Miranda, Susana, primary, Figueiredo, Ines, primary, Rodrigues, Daniel Nava, primary, Ward, Sarah, primary, Matthews, Ruth, primary, Parmar, Mona, primary, Turner, Alison, primary, Tunariu, Nina, primary, Chopra, Neha, primary, Gevensleben, Heidrun, primary, Turner, Nicholas C., primary, Ruddle, Ruth, primary, Raynaud, Florence I., primary, Decordova, Shaun, primary, Swales, Karen E., primary, Finneran, Laura, primary, Hall, Emma, primary, Rugman, Paul, primary, Lindemann, Justin P.O., primary, Foxley, Andrew, primary, Lord, Christopher J., primary, Banerji, Udai, primary, Plummer, Ruth, primary, Basu, Bristi, primary, Lopez, Juanita S., primary, Drew, Yvette, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

48. Supplementary Figure S2 from Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition

Author

Goodall, Jane, primary, Mateo, Joaquin, primary, Yuan, Wei, primary, Mossop, Helen, primary, Porta, Nuria, primary, Miranda, Susana, primary, Perez-Lopez, Raquel, primary, Dolling, David, primary, Robinson, Dan R., primary, Sandhu, Shahneen, primary, Fowler, Gemma, primary, Ebbs, Berni, primary, Flohr, Penny, primary, Seed, George, primary, Rodrigues, Daniel Nava, primary, Boysen, Gunther, primary, Bertan, Claudia, primary, Atkin, Mark, primary, Clarke, Matthew, primary, Crespo, Mateus, primary, Figueiredo, Ines, primary, Riisnaes, Ruth, primary, Sumanasuriya, Semini, primary, Rescigno, Pasquale, primary, Zafeiriou, Zafeiris, primary, Sharp, Adam, primary, Tunariu, Nina, primary, Bianchini, Diletta, primary, Gillman, Alexa, primary, Lord, Christopher J., primary, Hall, Emma, primary, Chinnaiyan, Arul M., primary, Carreira, Suzanne, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

49. Supplemental Table S1 from Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition

Author

Goodall, Jane, primary, Mateo, Joaquin, primary, Yuan, Wei, primary, Mossop, Helen, primary, Porta, Nuria, primary, Miranda, Susana, primary, Perez-Lopez, Raquel, primary, Dolling, David, primary, Robinson, Dan R., primary, Sandhu, Shahneen, primary, Fowler, Gemma, primary, Ebbs, Berni, primary, Flohr, Penny, primary, Seed, George, primary, Rodrigues, Daniel Nava, primary, Boysen, Gunther, primary, Bertan, Claudia, primary, Atkin, Mark, primary, Clarke, Matthew, primary, Crespo, Mateus, primary, Figueiredo, Ines, primary, Riisnaes, Ruth, primary, Sumanasuriya, Semini, primary, Rescigno, Pasquale, primary, Zafeiriou, Zafeiris, primary, Sharp, Adam, primary, Tunariu, Nina, primary, Bianchini, Diletta, primary, Gillman, Alexa, primary, Lord, Christopher J., primary, Hall, Emma, primary, Chinnaiyan, Arul M., primary, Carreira, Suzanne, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

50. Supplementary Data from Targeting the p300/CBP Axis in Lethal Prostate Cancer

Author

Welti, Jonathan, primary, Sharp, Adam, primary, Brooks, Nigel, primary, Yuan, Wei, primary, McNair, Christopher, primary, Chand, Saswati N., primary, Pal, Abhijit, primary, Figueiredo, Ines, primary, Riisnaes, Ruth, primary, Gurel, Bora, primary, Rekowski, Jan, primary, Bogdan, Denisa, primary, West, William, primary, Young, Barbara, primary, Raja, Meera, primary, Prosser, Amy, primary, Lane, Jordan, primary, Thomson, Stuart, primary, Worthington, Jenny, primary, Onions, Stuart, primary, Shannon, Jonathan, primary, Paoletta, Silvia, primary, Brown, Richard, primary, Smyth, Don, primary, Harbottle, Gareth W., primary, Gil, Veronica S., primary, Miranda, Susana, primary, Crespo, Mateus, primary, Ferreira, Ana, primary, Pereira, Rita, primary, Tunariu, Nina, primary, Carreira, Suzanne, primary, Neeb, Antje J., primary, Ning, Jian, primary, Swain, Amanda, primary, Taddei, David, primary, Schiewer, Matthew J., primary, Knudsen, Karen E., primary, Pegg, Neil, primary, and de Bono, Johann S., primary

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results