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Aural plaques are associated with and thought to be caused by one or more Equus caballus papillomaviruses (EcPV). Aural plaques have not previously been reported to be associated with squamous cell carcinoma (SCC).To describe a horse with aural plaques and squamous cell carcinoma (SCC) on the right pinna.A 28-year-old thoroughbred gelding presented for multiple plaques and a mass on the right pinna.Pinnal resection, histopathological investigation, multiple conventional PCRs for papillomavirus DNA and Sanger sequencing were performed.Multiple, raised, pale tan, fronded plaques covered 60% of the concave surface of the right pinna. Focally these plaques coalesced into an exophytic ulcerated mass near the base of the pinna. Multiple aural plaques and a SCC were diagnosed histopathologically. EcPV4 was detected via PCR in a sample of the SCC.This report demonstrates the possibility of malignant transformation from aural plaques to SCC on the pinna of a horse. To the best of the authors' knowledge, this is the first report of EcPV4 associated with SCC.背景‐普遍认为: 种或多种马乳头瘤病毒 (Equus caballus papillomaviruses，EcPV) 可以引起耳斑块。耳斑块尚未见有与鳞状细胞癌 (SCC) 相关的报道。 假设/目的‐报告: 匹有耳斑块的患马，其右侧耳廓发现鳞状细胞癌 (SCC)。 动物: 28岁纯种去势马，右侧耳廓出现多个斑块和一个肿块。 方法和材料: 耳廓切除术，组织病理学调查，多重常规PCR检测乳头状瘤病毒DNA，并进行双脱氧测序。 结果: 右侧耳廓凹面60%的面积上覆盖多个凸起的浅褐色斑块。这些斑块在耳廓基部附近，局部融合成外生性溃疡团块。组织病理学诊断为多发性耳斑块和SCC。通过PCR在SCC样本中检测到EcPV4。 结论和临床重要性: 本报告证明了马耳廓上耳斑块有可能恶变为 SCC 。据作者所知，这是EcPV4与SCC相关的首次报告。.Les plaques aurales sont associées et dues à un ou plus d’un EcPV (Equus caballus papillomaviruses). Elles n’ont pas encore été décrites en association à un carcinome épidermoïde (SCC). HYPOTHÈSES/OBJECTIFS: Décrire un cheval avec plaques aurales et carcinome épidermoïde (SCC) sur le pavillon droit.Un pur sang hongre de 28 ans est présenté pour plaques multiples et une masse au niveau du pavillon auriculaire droit. MATÉRIELS ET MÉTHODES: Une exérèse du pavillon, un examen histopathologique, plusieurs PCR pour recherche d’ADN de papillomavirus et séquençage Sanger ont été réalisés. RÉSULTATS: De multiples plaques surélevées, papillomateuses, blanchâtres, couvraient 60% de la surface concave du pavillon droit. Focalement ces plaques coalesçaient en une masse ulcérée exophytique près de la base du pavillon. De multiples plaques aurales et un SCC ont été diagnostiqués à l’examen histopathologique. L’EcPV4 a été détecté par PCR dans un échantillon du SCC.Cet article démontre la possibilité d’une transformation maligne de plaque aurale à SCC du pavillon d’un cheval. A la connaissance des auteurs, il s’agit de la première description d’EcPV4 associé à un SCC.Aurale Plaques stehen im Zusammenhang mit Equus caballus Papillomavirus (EcPV) und man geht davon aus, dass sie von einem oder mehreren dieser Papillomaviren verursacht werden. Es wurde bisher nicht davon berichtet, dass aurale Plaques mit einem Plattenepithelkarzinom (SCC) im Zusammenhang stehen könnten.Die Beschreibung eines Pferdes mit auralen Plaques und einem Plattenepithelkarzinom (SCC) an der rechten Pinna.Ein 28 Jahre alter Vollblutwallach, die wegen multipler Plaques und einer Masse an der rechten Pinna vorgestellt wurde.Eine Resektion der Pinna, eine histopathologische Untersuchung, multiple konventionelle PCR Untersuchungen auf Papillomavirus DNA, sowie Sanger Sequenzierung wurden durchgeführt.Multiple, erhabene blassbraune, wedelartige Plaques bedeckten 60% der konkaven Oberfläche der rechten Pinna. Fokal koaleszierten diese Plaques zu exophytisch ulzerierten Massen nahe der Basis der Pinna. Histopathologisch wurden multiple aurale Plaques und ein SCC diagnostiziert. EcPV4 wurde mittels PCR in einer SCC Probe entdeckt.Dieser Bericht demonstriert die Möglichkeit einer malignen Transformation von einem auralen Plaques zu einem SCC an der Pinna eines Pferdes. Nach bestem Wissen der Autoren handelt es sich hierbei um den ersten Bericht eines EcPV4 im Zusammenhang mit einem SCC.背景: 耳プラークは、1つまたは複数の馬パピローマウイルス（EcPV）に関連し、その原因と考えられている。耳プラークが扁平上皮癌（SCC）に関連していると以前には報告されていない。 仮説/目的: 右耳介に耳プラークおよび扁平上皮癌（SCC）がある馬について説明する。 供試動物: 複数のプラークと右耳介腫瘤を認めた28歳、サラブレッドの去勢馬。 材料と方法: 耳介切除術、組織病理学的調査、パピローマウイルスDNAの複数の従来のPCR、およびサンガー法によるシーケンスを実施した。 結果: 複数の隆起した淡褐色の葉状プラークが、右耳介の凹面の60％を覆っていた。焦点的には、これらのプラークは、耳介付け根近くの外向性潰瘍性腫瘤に合体した。複数の耳プラークおよびSCCが組織病理学的に診断された。 EcPV4は、SCCサンプルでPCRを介して検出された。 結論と臨床的重要性: 本レポートは、馬の耳プラークからSCCへの悪性転換の可能性を示している。著者の知る限り、これはSCCに関連するEcPV4の最初のレポートである。.As placas aurais estão associadas e acredita‐se que sejam causadas por um ou mais tipos de papilomavírus de Equus caballus (PVEc). Não há relatos ainda de placas aurais associadas ao carcinoma de células escamosas (CCE). HIPÓTESE / OBJETIVOS: Descrever o caso de um cavalo com placas aurais e carcinoma de células escamosas (CCE) no pavilhão auricular direito.Um cavalo castrado puro‐sangue inglês de 28 anos de idade apresentado diversas placas e uma massa na orelha direita. MÉTODOS E MATERIAIS: Foram realizados: ressecção do pavilhão auricular, investigação histopatológica, múltiplas PCRs convencionais para DNA de papilomavírus e sequenciamento de Sanger.Múltiplas placas elevadas, amarronzadas a pálidas e vegetantes cobriam 60% da superfície côncava do pavilhão auricular direito. Focalmente, essas placas coalesceram em uma massa ulcerada exofítica perto da base do pavilhão auricular. Múltiplas placas aurais e um CCE foram diagnosticados histopatologicamente. O EcPV4 foi detectado por PCR em uma amostra do CCE. CONCLUSÕES E IMPORTÂNCIA CLÍNICA: Este relato demonstra a possibilidade da transformação maligna de placas aurais em CCE na orelha de um cavalo. De acordo com o conhecimento dos autores, este é o primeiro relato de EcPV4 associado a CCE.INTRODUCCIÓN: las placas aurales están asociadas y se cree que son causadas por uno o más virus papiloma de Equus caballus (EcPV). No se ha descrito previamente que las placas aurales estén asociadas con el carcinoma de células escamosas (SCC). HIPÓTESIS/OBJETIVOS: describir un caballo con placas aurales y carcinoma de células escamosas (SCC) en el pabellón auricular derecho. ANIMALES: un caballo castrado pura sangre de 28 años se presentó con múltiples placas y una masa en pabellón auricular derecho. MÉTODOS Y MATERIALES: se realizaron resección de la oreja, investigación histopatológica, múltiples PCR convencionales para DNA del virus del papiloma y secuenciación de Sanger. RESULTADOS: múltiples placas elevadas, de color pardo pálido y papilares cubrían el 60% de la superficie cóncava del pabellón auricular derecho. Focalmente, estas placas se unían en una masa ulcerada y exofítica cerca de la base de la oreja. Múltiples placas auditivas y un SCC fueron diagnosticados histopatológicamente. EcPV4 se detectó mediante PCR en una muestra de SCC. CONCLUSIONES E IMPORTANCIA CLÍNICA: este caso demuestra la posibilidad de transformación maligna de las placas auditivas a SCC en la oreja de un caballo. A entender de los autores, este es el primer informe de EcPV4 asociado con SCC.

Case summary A 9-year-old neutered male domestic shorthair cat was presented for multiple deep lesions on all four limbs and a nodule on the right pinna. The limb lesions ranged from nodules with necrotic surfaces to full-thickness ulcerations with exposure of muscles and tendons. The cat lived indoors only in a single-pet household and had no prior history of trauma. The owner reported that the lesions appeared abruptly and that the cat was not apparently painful or pruritic. Histopathology of the limb lesions and pinnal nodule confirmed severe lesions of the eosinophilic granuloma complex. Resolution of lesions was achieved with a combination of antibiotics, prednisolone, topical therapies, diet change and ciclosporin. Relevance and novel information This case report demonstrates a severe, aggressive presentation of eosinophilic granuloma complex. It will expose practitioners to atypical clinical signs of this commonly diagnosed disease.

A 7-year-old, white, domestic short hair, female cat was presented with an aural hematoma of the right pinna, which had been partially resected a year previously. A 3 × 4 cm mass, macroscopically similar to an auricular hematoma, was visible on the convex surface and a smaller vascular lesion was present on the ear margin. Cytological examination of the smaller mass was suggestive of hemangiosarcoma, and a diagnosis confirmed by histopathologic and immunohistochemical tests. Complete pinnectomy with a wide margin was performed and during the 3-year follow-up, the cat had no local recurrence or metastasis. We conclude that hemangiosarcoma should be considered as a potential differential diagnosis in white-coated cats with an unusual clinical presentation of aural hematoma.

Background The aetiology and appropriate treatment for auricular chondritis in the dog are currently unclear. This report describes a unique presentation and successful treatment of a dog with auricular chondritis. Clinical summary A 12-year-old, female spayed, Labrador retriever dog was presented for severe pain thought to be neurological in origin. The pain was located to the right pinna and two punch biopsies were acquired and evaluated, revealing lymphoplasmacytic to pyogranulomatous inflammation involving the auricular cartilage with no infectious agents. Treatment with systemic oral prednisone resulted in resolution of clinical signs within four weeks of initiation of treatment. The dog remained free of clinical signs for six months following discontinuation of treatment before being euthanized for an unrelated reason. Conclusions Further evaluation of canine auricular chondritis is needed, yet pain may be a prominent finding; monotherapy with systemic prednisone may provide quick and complete resolution of clinical sysmptoms.

Arteriovenous malformations (AVMs) of the scalp are remarkably rare. We report a case of 20 years old female complaining of swelling over right pinna and scalp since 2 years with known history of trauma. This case report represents pathogenesis, clinical features and management of the disease.

Ramsay Hunt Syndrome is a rare complication of herpes zoster in which reactivation of latent varicella zoster virus infection in the geniculate ganglion causes otalgia, auricular vesicles and lower motor neuron facial palsy. A 52-year-old man presented to us with complaints of vesicular eruptions over the right pinna, otalgia and facial weakness i.e. deviation of the angle of mouth to the left side and inability to close the right eye from last 3 days. A diagnosis of Ramsay Hunt Syndrome with grade V facial palsy was made. Intravenous acyclovir and oral steroids were started. Patient showed marked improvement within 10 days. For facial palsy, rehabilitation therapy was also given.

The directivity index is a parameter that is commonly used to characterize the performance of directional hearing aids, and is determined from the measured directional response. Since this response is different for a hearing aid worn on a person as compared to when it is in a free field, directivity index measurements of hearing aids are usually done under simulated real-ear conditions. Details are provided regarding the NIST system for measuring the hearing aid directivity index under these conditions and how this system is used to implement a standardized procedure for performing such measurements. This procedure involves a sampling method that utilizes sound source locations distributed in a semi-aligned zone array on an imaginary spherical surface surrounding a standardized acoustical test manikin. The capabilities of the system were demonstrated over the frequency range of one-third-octave bands with center frequencies from 200 Hz to 8000 Hz through NIST participation in an interlaboratory comparison. This comparison was conducted between eight different laboratories of members of Working Group S3/WG48, Hearing Aids, established by Accredited Standards Committee S3, Bioacoustics, which is administered by the Acoustical Society of America and accredited by the American National Standards Institute. Directivity measurements were made for a total of six programmed memories in two different hearing aids and for the unaided manikin with the manikin right pinna accompanying the aids. Omnidirectional, cardioid, and bidirectional response patterns were measured. Results are presented comparing the NIST data with the reference values calculated from the data reported by all participating laboratories.

The pinnae and external ear canals in ferrets are fairly small. Many breeders tattoo the ears of the ferrets. In the USA, one major breeder puts two dots in the right pinna signifying neuter/spay and demusking (Fig. 15.1). A breeder in Canada does a stripe in the right ear. Laboratory animal sources tend to putin small metal clip ear tags with individual numbers (Fig. 15.2). The pinna sometimes becomes infected or traumatised around these clips. Ferrets may tear them out; resulting in damage to the pinna.

Auricular perichondritis is a dangerous complication of the traumatized ear that can lead to residual deformity. The most common pathogen is Pseudomonas aeruginosa, followed by Staphylococcus aureus. A 14 year old female presented to the emergency department (ED) complaining of pain and swelling in her right pinna for two weeks after an ear piercing, she was treated with antibiotics and showed a complete resolution. Prompt and early diagnosis of perichondritis is primordial to avoid potential esthetic sequelae.

A 12-year-old girl presented to us with a swelling over the lateral surface of the right pinna of 4 years duration. Examination revealed an irregular mass arising from lateral surface of the pinna obscuring the external auditory canal. The lesion was not ulcerated. Wide excision of mass done and sent for Histopathological examination which revealed Tricho folliculoma. This case is being reported as it is a rare skin adnexal tumor arising from an unusual site.

We describe a case of basal cell carcinoma of right pinna in a 54 year old man. The patient underwent wide local excision of the lesion with lateral temporal bone resection. The defect created was reconstructed using Pectoralis major myocutaneous flap on same side in collaboration with plastic and reconstructive surgeons. Review after 6 months does not reveal any signs of recurrence.

This case report describes for the first time sarcoids in tapirs (Tapirus bairdii), namely, a 2-year-old male and a 3.6-year-old female born and housed at the same facility. The male presented with a 3-cm nodular, red, pedunculated, hairless, ulcerated mass on the inner surface of the left pinna. No recurrence or additional growths were present during the 3 years following surgical excision of the mass. The female presented with a similar 2-cm mass on the inner surface of the right pinna, which recurred 2 months following surgical excision, but was subsequently successfully treated locally with liquid nitrogen with no further recurrence during a 2-year follow-up period. Histologically, these two masses closely resembled equine sarcoids. Similarly, an association with bovine papillomavirus 1 was demonstrated using polymerase chain reaction and in situ hybridization.

Objective The aim of this study was to describe a rare intra-auricular sinus. An otherwise healthy 15-year-old girl presented with recurrent infections in her right pinna from early infancy. Physical examination revealed a draining sinus which opened to the descending helical limb, while its cystic component was entrapped within the cartilaginous antitragus. Comprehensive surgical excision was performed after the tract and the more distal cyst was delineated. Surgical pathology revealed a true sinus, measuring 2 cm. Follow-up was unremarkable. Discussion In addition to the two previously described variants of pre-auricular cyst: the classic variant (the pit is anterior to the external auditory canal) and the postauricular variant (the pit is behind the ascending limb of the helix), we suggest a third variant which opens to the descending helical rim.

A case of haemangioma with arterio-venous fistula involving the right pinna in a 25 year old female is being reported. The lesion including the pinna was excised surgically. Clinically it was labelled as an arterio-venous fistula and reported to be haemangioma histopathologically.