1,132 results on '"Right Colectomy"'
Search Results
2. Robotic MIS With Dexter
- Published
- 2024
3. Robotic Right Colectomy with Complete Mesocolic Excision and Central Vascular Ligation. Extended Right Colectomy
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Ceccarelli, Graziano, Bugiantella, Walter, Mariani, Lorenzo, Rondelli, Fabio, Tian, Brian, Arteritano, Federica, De Rosa, Michele, Ceccarelli, Graziano, editor, and Coratti, Andrea, editor
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- 2024
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4. A first report of right-hemicolectomy for ascending colon cancer in Japan with the da Vinci SP surgical robot system.
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Noda, Ai, Okuya, Koichi, Akizuki, Emi, Miyo, Masaaki, Ishii, Masayuki, Miura, Ryo, Ichihara, Momoko, Toyota, Maho, Ito, Tatsuya, Ogawa, Tadashi, Kimura, Akina, and Takemasa, Ichiro
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COLON cancer ,SURGICAL robots ,RIGHT hemicolectomy ,MINIMALLY invasive procedures ,COLORECTAL cancer ,ONCOLOGIC surgery - Abstract
Background: The da Vinci SP robotic surgical system received regulatory approval for use in colorectal cancer surgery in Japan in April 2023. Given the advantages of the precision of a robot and the postoperative cosmesis of single-site surgery, the system is expected to be further utilized for minimally invasive surgeries, in addition to the curative and safety-assured laparoscopic technique. Case presentation: A 73-year-old man presented at our hospital with positive fecal occult blood. He was diagnosed with cT2N0M0 (Stage I) ascending colon cancer and underwent a right hemicolectomy, which was performed with the da Vinci SP system. The operation was performed safely, and the patient was discharged without complications. Pathology findings showed that complete mesocolic excision was achieved. Conclusions: Herein, we report the first colorectal cancer surgery performed using the da Vinci SP system in Japan. The use of this robotic surgical system with access forms for right hemicolectomy is safe and oncologically appropriate. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Evaluation of an Arterial Calcification Score as a Predictive Factor of Anastomotic Leakage in Right Colectomy (RIGHTCOLOCALCI)
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- 2023
6. A case of pancreaticoduodenal artery bleeding after laparoscopic right colectomy requiring open hemostasis
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Rika Ono, Tetsuro Tominaga, Takashi Nonaka, Yuma Takamura, Kaido Oishi, Toshio Shiraishi, Shintaro Hashimoto, Keisuke Noda, Terumitsu Sawai, and Takeshi Nagayasu
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Bleeding ,Pancreaticoduodenal artery ,Right colectomy ,Surgery ,RD1-811 - Abstract
Abstract Background Pancreatic and duodenal-related complications after right colectomy carry a higher risk of mortality. Case presentation A 64-year-old woman underwent laparoscopic right colectomy for a laterally spreading tumor in the cecum. On postoperative day 10, she experienced sudden hematemesis. Contrast-enhanced computed tomography (CT) of the abdomen showed a large amount of hemorrhage in the stomach, but no obvious extravasation. In addition, free air was observed near the duodenal bulb. Despite blood transfusion, vital signs remained unstable and emergency surgery was performed. The abdomen was opened through midline incisions in the upper and lower abdomen. A fragile wall and perforation were observed at the border of the left side of the duodenal bulb and pancreas, with active bleeding observed from inside. As visualization of the bleeding point proved difficult, the duodenum was divided circumferentially to confirm the bleeding point and hemostasis was performed using 4-0 PDS. The left posterior wall of the duodenum was missing, exposing the pancreatic head. For reconstruction, the jejunum was elevated via the posterior colonic route and the duodenal segment and elevated jejunum were anastomosed in an end-to-side manner. Subsequently, gastrojejunal and Brown anastomoses were added. Drains were placed before and after the duodenojejunal anastomosis. Postoperative vital signs were stable and the patient was extubated on postoperative day 1. Follow-up contrast-enhanced CT of the abdomen showed no active bleeding, and the patient was discharged home on postoperative day 21. As of 6 months postoperatively, the course of recovery has been uneventful. Conclusions We encountered a case of pancreaticoduodenal artery hemorrhage after laparoscopic right colectomy. Bleeding at this site can prove fatal, so treatment plans should be formulated according to the urgency of the situation.
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- 2024
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7. Incisional Hernia After Laparoscopic Right Colectomy for Colorectal Cancer: A Prospective Study with Retrospective Control on Intracorporeal Versus Extracorporeal Anastomosis.
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Pesce, Antonio, Petrarulo, Francesca, Fabbri, Nicolò, Portinari, Mattia, and Feo, Carlo Vittorio
- Abstract
Background: Incisional hernias often occur after laparoscopic colorectal surgery, but the precise risk factors are not fully understood. This study's primary aim was to compare the incidence of incisional hernias following laparoscopic right colectomy with intracorporeal anastomotic reconstruction (ICA) versus extracorporeal anastomotic reconstruction (ECA). Materials and Methods: A cohort study compared two groups of patients who underwent elective laparoscopic right colectomy for colon cancer following a standardized perioperative enhanced recovery program (ERP): a prospective group underwent ICA from January 2018 to February 2020 and a retrospective group underwent ECA from January 2013 to December 2016. The presence of incisional hernias was assessed by reviewing patients' follow-up computed tomography scans or evaluating the patients by telephone interview or outpatient office visit and diagnostic imaging. Secondary objectives included the hospital length of stay, postoperative complications, 30-day readmission rate, reoperation, and mortality. Results: The study included 89 patients who had laparoscopic right colectomy for malignant colon neoplasms. Among these, 48 underwent ECA (ECA group), and 41 had ICA (ICA group). At a median follow-up of 36 months, incisional hernia was observed in 1 patient (2.4%) in the ICA group, in contrast to 11 (22.9%) confirmed cases in the ECA group (P = .010). The length of hospital stay was similar between the two groups (5 days versus 4 days; P = .064). The two groups showed similarities in terms of postoperative complications (P = .093), hospital readmission (P = .999), and the rate of reoperation within 30 days (P = .461). Conclusions: The ICA technique was associated with a reduced risk of incisional hernias compared with the ECA technique, with similar outcomes in short-term postoperative complications and overall patient recovery. [ABSTRACT FROM AUTHOR]
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- 2024
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8. A case of pancreaticoduodenal artery bleeding after laparoscopic right colectomy requiring open hemostasis.
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Ono, Rika, Tominaga, Tetsuro, Nonaka, Takashi, Takamura, Yuma, Oishi, Kaido, Shiraishi, Toshio, Hashimoto, Shintaro, Noda, Keisuke, Sawai, Terumitsu, and Nagayasu, Takeshi
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HEMOSTASIS ,SURGICAL emergencies ,LAPAROSCOPIC surgery ,HEMORRHAGE ,COLECTOMY ,ARTERIES ,DUODENAL obstructions - Abstract
Background: Pancreatic and duodenal-related complications after right colectomy carry a higher risk of mortality. Case presentation: A 64-year-old woman underwent laparoscopic right colectomy for a laterally spreading tumor in the cecum. On postoperative day 10, she experienced sudden hematemesis. Contrast-enhanced computed tomography (CT) of the abdomen showed a large amount of hemorrhage in the stomach, but no obvious extravasation. In addition, free air was observed near the duodenal bulb. Despite blood transfusion, vital signs remained unstable and emergency surgery was performed. The abdomen was opened through midline incisions in the upper and lower abdomen. A fragile wall and perforation were observed at the border of the left side of the duodenal bulb and pancreas, with active bleeding observed from inside. As visualization of the bleeding point proved difficult, the duodenum was divided circumferentially to confirm the bleeding point and hemostasis was performed using 4-0 PDS. The left posterior wall of the duodenum was missing, exposing the pancreatic head. For reconstruction, the jejunum was elevated via the posterior colonic route and the duodenal segment and elevated jejunum were anastomosed in an end-to-side manner. Subsequently, gastrojejunal and Brown anastomoses were added. Drains were placed before and after the duodenojejunal anastomosis. Postoperative vital signs were stable and the patient was extubated on postoperative day 1. Follow-up contrast-enhanced CT of the abdomen showed no active bleeding, and the patient was discharged home on postoperative day 21. As of 6 months postoperatively, the course of recovery has been uneventful. Conclusions: We encountered a case of pancreaticoduodenal artery hemorrhage after laparoscopic right colectomy. Bleeding at this site can prove fatal, so treatment plans should be formulated according to the urgency of the situation. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
9. Intracorporeal or extracorporeal anastomosis after minimally invasive right colectomy: a systematic review and meta-analysis.
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Squillaro, A. I., Kohn, J., Weaver, L., Yankovsky, A., Milky, G., Patel, N., Kreaden, U. S., and Gaertner, W. B.
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COLECTOMY , *MINIMALLY invasive procedures , *SURGICAL anastomosis , *SURGICAL site infections , *SURGICAL complications , *LENGTH of stay in hospitals - Abstract
Purpose: As part of the wide adoption of minimally invasive surgery, intracorporeal anastomosis is becoming increasingly common. The benefits of minimally invasive versus open right colectomy are well known although the additional benefits of an intracorporeal anastomosis, performed laparoscopically or robotically, are unclear. The aim of this study was to assess the current literature comparing intracorporeal and extracorporeal anastomosis in the setting of laparoscopic and robotic-assisted right colectomy. Methods: A systematic review and meta-analysis was conducted according to PRISMA and AMSTAR methods. Studies included were randomized controlled trials and prospective or retrospective cohort studies, between January 1 2010 and July 1 2021, comparing intracorporeal and extracorporeal anastomosis with laparoscopic and robotic approaches. Four groups were identified: laparoscopic extracorporeal anastomosis (L-ECA), laparoscopic intracorporeal anastomosis (L-ICA), robotic extracorporeal anastomosis (R-ECA), and robotic intracorporeal anastomosis (R-ICA). Operative time, rate of conversion to an open procedure, surgical site infection, reoperation within 30 days, postoperative complications within 30 days, and length of hospital stay were assessed. Results: Twenty-one retrospective cohort studies were included in the final analysis. R-ICA and R-ECA had comparable operative times, but a robotic approach required more time than laparoscopic (68 min longer, p < 0.00001). Conversion to open surgery was 55% less likely in the R-ICA group vs. L-ICA, and up to 94% less likely in the R-ICA group in comparison to the R-ECA group. Length of hospital stay was shorter for R-ICA by a half day vs. R-ECA, and up to 1 day less vs. L-ECA. There were no differences in postoperative complications, reoperations, or surgical site infections, regardless of approach. However, the included studies all had high risks of bias due to confounding variables and patient selection. Conclusion: Robotic-assisted right colectomy with intracorporeal anastomosis was associated with shorter length of hospitalization and decreased rate of conversion to open surgery, compared to either laparoscopic or extracorporeal robotic approaches. Prospective studies are needed to better understand the true impact of robotic approach and intracorporeal anastomosis in right colectomy. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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10. Robotic right versus left colectomy for colorectal neoplasia: a systemic review and meta-analysis.
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Solis-Pazmino, Paola, Oka, Kimberly, La, Kristina, Termeie, Orly, Ponce, Oscar, Figueroa, Luis, Weston, Antonio, Machry, Mayara, Cohen, Jason, Barnajian, Moshe, and Nasseri, Yosef
- Abstract
Previous studies comparing right and left colectomies have shown variable short-term outcomes. Despite the rapid adoption of robotics in colorectal operations, few studies have addressed outcome differences between robotic right (RRC) and left (RLC) colectomies. Therefore, we sought to compare the short-term outcomes of RRC and RLC for neoplasia. This is a systematic review and meta-analysis of articles published from the time of inception of the datasets to May 1, 2022. The electronic databases included English publications in Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, and Scopus. A total of 13,514 patients with colon neoplasia enrolled in 9 comparative studies were included. The overall mean age was 64.1 years (standard deviation [SD] ± 9.8), and there was a minor female predominance (52% female vs. 48% male). 8656 (64.0%) underwent RRC and 4858 (36.0%) underwent RLC. The ASA score 1 of − 2 in the LRC group was 37% vs. 21% in the R. Whereas the ASA score 3–4 was 62% in the LRC vs. 76% in RRC. Moreover, the mean of the Charlson Comorbidity Score in the LRC was 4.3 (SD 1.9) vs. 3.1 (SD 2.3) in the RRC. Meta-analysis revealed a significantly higher rate of ileus in RRC (10%) compared to RLC (7%) (OR 1.46, 95% CI 1.27–1.67). Additionally, operative time was significantly shorter by 22.6 min in RRC versus LRC (95% CI − 37.4–7.8; p < 0.001). There were no statistically significant differences between RRC and RLC in conversion to open operation, estimated blood loss, wound infection, anastomotic leak, reoperation, readmission, and hospital length of stay. In this only meta-analysis comparing RRC and LRC for colon neoplasia, we found that RRC was independently associated with a shorter operative time but increased risk of ileus. [ABSTRACT FROM AUTHOR]
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- 2023
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11. Intracorporeal vs Extracorporeal Anastomosis for Right Colectomy
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Lujan, Henry J., Maciel, Victor, Ferguson, Mark K., Series Editor, Umanskiy, Konstantin, editor, and Hyman, Neil, editor
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- 2023
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12. Should Laparoscopic Complete Mesocolic Excision Be Offered to Elderly Patients to Treat Right-Sided Colon Cancer?
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Michele Mazzola, Lorenzo Ripamonti, Alessandro Giani, Pietro Carnevali, Matteo Origi, BrunocDomenico Alampi, Irene Giusti, Pietro Achilli, Camillo Leonardo Bertoglio, Carmelo Magistro, and Giovanni Ferrari
- Subjects
complete mesocolic excision ,laparoscopic surgery ,right colectomy ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background: Despite its potential oncologic benefit, complete mesocolic excision (CME) has rarely been offered to elderly patients. The present study evaluated the effect of age on postoperative outcomes among patients undergoing laparoscopic right colectomies with CME for right-sided colon cancer (RCC). Methods: Data of patients undergoing laparoscopic right colectomies with CME for RCC between 2015 and 2018 were retrospectively analyzed. Selected patients were divided into two groups: the under-80 group and the over-80 group. Surgical, pathological, and oncological outcomes among the groups were compared. Results: A total of 130 patients were selected (95 in the under-80 group and 35 in the over-80 group). No difference was found between the groups in terms of postoperative outcomes, except for median length of stay and adjuvant chemotherapy received, which were in favor of the under-80 group (5 vs. 8 days, p < 0.001 and 26.3% vs. 2.9%, p = 0.003, respectively). No difference between the groups was found regarding overall survival and disease free survival. Using multivariate analysis, only the ASA score > 2 (p = 0.01) was an independent predictor of overall complications. Conclusions: laparoscopic right colectomy with CME for RCC was safely performed in elderly patients ensuring similar oncological outcomes compared to younger patients.
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- 2023
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13. Short- and long-term outcome differences between patients undergoing left and right colon cancer surgery: cohort study
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Kuliavas, Justas, Marcinkevičiūtė, Kristina, Baušys, Augustinas, Bičkaitė, Klaudija, Baušys, Rimantas, Abeciūnas, Vilius, Degutytė, Austėja Elžbieta, Kryžauskas, Marius, Stratilatovas, Eugenijus, Dulskas, Audrius, Poškus, Tomas, and Strupas, Kęstutis
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- 2024
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14. Caudal-to-Cranial Approach for Right Colectomy with Complete Mesocolic Excision in Colon Cancer: A Systematic Review and Meta-analysis.
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Maatouk, Mohamed, Safta, Yacine Ben, Kbir, Ghassen Hamdi, Mabrouk, Aymen, Dhaw, Anis Ben, Haouet, Karim, and Moussa, Mounir Ben
- Abstract
Background: A newly emerging approach "caudal to cranial" with complete mesenteric excision (CME) has recently been proposed for right colectomy in patients with right colon cancer. To date, only a few studies about this approach have appeared. Our study aims to investigate the safety and efficacy of this new technique. Methods: A systematic review of the literature was conducted to evaluate the evidence regarding short- and long-term outcomes after the caudal-to-cranial approach (CCA). Methodological Index for Non-Randomized Studies was used to evaluate methodological quality. The risk of bias was assessed using Robvis tool. Meta-analyses have been conducted for the outcomes of studies comparing CCA with other techniques. Results: We found six studies from 2017 to 2021 with a total of 594 patients. The postoperative complications and oncological outcomes were acceptable. Two studies comparing CCA to medial-to-lateral approach were included in the meta-analysis. No differences were found between the techniques regarding to operative time, length of hospital stay, overall morbidity, and number of lymph nodes. Conclusion: Although the interpretation of our findings may be restrained by methodological limitations, risk of bias, and the absence of well-designed randomized controlled trials, CCA with CME in right-sided colon cancer may be a feasible and safe procedure. [ABSTRACT FROM AUTHOR]
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- 2023
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15. COMPARISON OF POSTOPERATIVE AND ONCOLOGICAL OUTCOMES IN ROBOTIC AND OPEN RIGHT COLECTOMY FOR COLON CANCER.
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YÜKSEL, Sercan, TOPAL, Uğur, BATUR, Ece, DEMİR, Anıl, ÇALIKOĞLU, İsmail, KARAKÖSE, Erdal, ERCAN, Erdal, TEKE, Zafer, and BEKTAŞ, Hasan
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COLECTOMY , *COLON cancer , *RIGHT hemicolectomy , *SURGICAL complications , *SURGICAL robots , *LYMPHATIC metastasis - Abstract
Objective: This study aims to compare the short-term outcomes of robotic right hemicolectomy for right-sided colon cancer to those of conventional open right hemicolectomy. Material and Method: Patients who underwent surgical treatment for right-sided colorectal cancer between 2020 and 2022 were included in the study. Patients had been divided into two groups: Group 1, who underwent conventional surgery, and Group 2, who underwent robotic surgery. Clinical data and preoperative findings of patients were compared between the groups. Result: A total of 51 patients participated in our study. Group 1 consisted of 39 patients and Group 2 consisted of 12 patients. The mean age was 60.7 vs. 62.3 (p=0.773). No conversions or intraoperative complications occurred. Extended right hemicolectomy was performed in 23.1% vs. 8.36% (p=0.083). The operation time was longer in Group 2 (2.84 vs. 3.04, p=0.023). One patient in Group 1 underwent reoperation for ileus during the postoperative period. T3-stage tumors (48.7% vs. 50%, p=0.794) and N0 lymph node metastasis (38.5% vs. 41.7%, p=0.827) were detected most frequently. The total number of lymph nodes dissected was 37.2 vs. 41.9 (p=0.179). The number of malignant lymph nodes was 2.54 vs. 6.42 (p=0.881). The most common Clavien-Dindo score was 1 in both groups (79.5% vs. 83.3%, p=0.339). The length of stay was similar between the groups (6.38 vs. 5.92, p=0.156). Readmission occurred in 6 patients in Group 1, with reasons being anastomotic leakage, ileus, and general condition disorder. Conclusion: Our experience shows the feasibility and safety of robotic surgery for the treatment of right-sided colon cancer. This method has provided satisfactory short-term outcomes. [ABSTRACT FROM AUTHOR]
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- 2023
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16. Comparison of robotic right colectomy and laparoscopic right colectomy: a systematic review and meta-analysis.
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Zheng, Jianchun, Zhao, Shuai, Chen, Wei, Zhang, Ming, and Wu, Jianxiang
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BLOOD loss estimation , *COLECTOMY , *LYMPHADENECTOMY , *LENGTH of stay in hospitals , *SURGICAL anastomosis , *ABDOMINAL surgery - Abstract
Background: For right colon surgery, there is an increasing body of literature comparing the safety of robotic right colectomy (RRC) with laparoscopic right colectomy (LRC). The aim of the present systematic review and meta-analysis is to assess the safety and efficacy of RRC versus LRC, including homogeneous subgroup analyses for extracorporeal anastomosis (EA) and intracorporeal anastomosis (IA). Methods: PubMed, Web of Science, Embase, and Cochrane Library databases were searched for studies published between January 2000 and January 2022. Length of hospital stay, operation time, rate of conversion to laparotomy, time to first flatus, number of harvested lymph nodes, estimated blood loss, rate of overall complication, ileus, anastomotic leakage, wound infection, and total costs were measured. Results: Forty-two studies (RRC: 2772 patients; LRC: 12,469 patients) were evaluated. Regardless of the type of anastomosis, RRC showed shorter length of hospital stay, lower rate of conversion to laparotomy, shorter time to first flatus, lower rate of overall complications, and a higher number of harvested lymph nodes compared with LRC, but longer operative time and higher total costs. In the IA subgroup, RRC had a shorter length of hospital stay, longer operative time, and lower rate of conversion to laparotomy compared with LRC, with no difference for the remaining outcomes. In the EA subgroup, RRC had a longer operative time, lower estimated blood loss, lower rate of overall complications, and higher total costs compared with LRC, with the other outcomes being similar. Conclusion: The safety and efficacy of RRC is superior to LRC, especially when an intracorporeal anastomosis is performed. Most included articles were retrospective, offering low-quality evidence and limited conclusions. [ABSTRACT FROM AUTHOR]
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- 2023
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17. Safe implementation of robotic right colectomy with intracorporeal anastomosis.
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Van Eetvelde, E., Violon, S., Poortmans, N., Stijns, J., Duinslaeger, M., Vanhoeij, M., Buyl, R., and Jacobs-Tulleneers-Thevissen, D.
- Abstract
The robotic platform can overcome technical difficulties associated with laparoscopic colon surgery. Transitioning from laparoscopic right colectomy with extracorporeal anastomosis (ECA) to robotic right colectomy with intracorporeal anastomosis (ICA) is associated with a learning phase. This study aimed at determining the length of this learning phase and its associated morbidity. We retrospectively analyzed all laparoscopic right colectomies with ECA (n = 38) and robotic right colectomies with ICA (n = 67) for (pre)malignant lesions performed by a single surgeon between January 2014 and December 2020. CUSUM-plot analysis of total procedure time was used for learning curve determination of robotic colectomies. Non-parametric tests were used for statistical analysis. Compared to laparoscopy, the learning phase robotic right colectomies (n = 35) had longer procedure times (p < 0.001) but no differences in anastomotic leakage rate, length of stay or 30-day morbidity. Conversion rate was reduced from 16 to 3 percent in the robotic group. This study provides evidence that robotic right colectomy with ICA can be safely implemented without increasing morbidity. [ABSTRACT FROM AUTHOR]
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- 2023
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18. The effect of mechanical bowel preparation on postoperative complications in laparoscopic right colectomy: a retrospective propensity score matching analysis.
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Perets, Michal, Yellinek, Shlomo, Carmel, Ofra, Boaz, Elad, Dagan, Amir, Horesh, Nir, Reissman, Petachia, and Freund, Michael R.
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COLECTOMY , *PROPENSITY score matching , *BOWEL preparation (Procedure) , *SURGICAL complications , *SURGICAL site infections , *LAPAROSCOPIC surgery , *COLON cancer - Abstract
Purpose: To assess whether full bowel preparation affects 30-day surgical outcomes in laparoscopic right colectomy for colon cancer. Methods: A retrospective chart review of all elective laparoscopic right colectomies performed for colonic adenocarcinoma between Jan 2011 and Dec 2021. The cohort was divided into two groups—no bowel preparation (NP) group and patients who received full bowel preparation (FP), including oral and mechanical cathartic bowel preparation. All anastomoses were extracorporeal stapled side-to-side. The two groups were compared at baseline and then were matched using propensity score based on demographic and clinical parameters. The primary outcome was 30-day postoperative complication rate, mainly anastomotic leak (AL) and surgical site infection (SSI) rate. Results: The original cohort included 238 patients with a median age of 68 (SD 13) and equal M:F ratio. Following propensity score matching, 93 matched patients were included in each group. Analysis of the matched cohort showed a significantly higher overall complication rate in the FP group (28 vs 11.8%, p = 0.005) which was mostly due to minor type II complications. There were no differences in major complication rates, SSI, ileus, or AL rate. Although operative time was significantly longer in the FP group (119 vs 100 min, p ≤ 0.001), length of stay was significantly shorter in the FP group (5 vs 6 days, p = 0.001). Conclusions: Aside from a shorter hospital stay, full mechanical bowel preparation for laparoscopic right colectomy does not seem to have any benefit and may be associated with a higher overall complication rate. [ABSTRACT FROM AUTHOR]
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- 2023
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19. Should Laparoscopic Complete Mesocolic Excision Be Offered to Elderly Patients to Treat Right-Sided Colon Cancer?
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Mazzola, Michele, Ripamonti, Lorenzo, Giani, Alessandro, Carnevali, Pietro, Origi, Matteo, Alampi, BrunocDomenico, Giusti, Irene, Achilli, Pietro, Bertoglio, Camillo Leonardo, Magistro, Carmelo, and Ferrari, Giovanni
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RIGHT hemicolectomy , *OLDER patients , *COLECTOMY , *COLON cancer , *PROGRESSION-free survival , *LAPAROSCOPIC surgery , *ADJUVANT chemotherapy - Abstract
Background: Despite its potential oncologic benefit, complete mesocolic excision (CME) has rarely been offered to elderly patients. The present study evaluated the effect of age on postoperative outcomes among patients undergoing laparoscopic right colectomies with CME for right-sided colon cancer (RCC). Methods: Data of patients undergoing laparoscopic right colectomies with CME for RCC between 2015 and 2018 were retrospectively analyzed. Selected patients were divided into two groups: the under-80 group and the over-80 group. Surgical, pathological, and oncological outcomes among the groups were compared. Results: A total of 130 patients were selected (95 in the under-80 group and 35 in the over-80 group). No difference was found between the groups in terms of postoperative outcomes, except for median length of stay and adjuvant chemotherapy received, which were in favor of the under-80 group (5 vs. 8 days, p < 0.001 and 26.3% vs. 2.9%, p = 0.003, respectively). No difference between the groups was found regarding overall survival and disease free survival. Using multivariate analysis, only the ASA score > 2 (p = 0.01) was an independent predictor of overall complications. Conclusions: laparoscopic right colectomy with CME for RCC was safely performed in elderly patients ensuring similar oncological outcomes compared to younger patients. [ABSTRACT FROM AUTHOR]
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- 2023
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20. Conversion to Open Surgery During Minimally Invasive Right Colectomy for Cancer: Results from a Large Multinational European Study.
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Martínez-Pérez, Aleix, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Winter, Des C, Carcoforo, Paolo, Celentano, Valerio, Chiarugi, Massimo, Di Saverio, Salomone, Bianchi, Giorgio, Frontali, Alice, Fuks, David, Genova, Pietro, Guerrieri, Mario, Kraft, Miquel, Lakkis, Zaher, Le Roy, Bertrand, Micelli Lupinacci, Renato, Milone, Marco, Petri, Roberto, and Scabini, Stefano
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COLECTOMY , *MINIMALLY invasive procedures , *OPERATIVE surgery , *ABDOMINAL surgery , *SURGICAL complications , *COLON cancer - Abstract
Background: The risk of conversion to open surgery is inevitably present during any minimally invasive colorectal surgical procedure. Conversions have been associated with adverse postoperative and oncologic outcomes. No previous study has evaluated the specific causes and consequences of conversion during a minimally invasive right colectomy (MIS-RC). Materials and Methods: We analyzed the Minimally invasivE surgery for oncologic Right ColectomY (MERCY) study database including patients who underwent laparoscopic or robotic RC because of colon cancer between 2014 and 2020. Descriptive analyses were performed to determine the different reasons for conversion. Uni- and multivariate logistic regressions were run to identify potential variables associated with this outcome. Cox regression analyses were used to evaluate the impact of conversion on tumor recurrence. Results: Over a total of 1574 MIS-RC, 120 (7.6%) were converted to open surgery. The main reasons for conversion were procedural difficulties related to adherences from previous abdominal surgical procedures (39.2%), or owing to large tumor size or infiltration of adjacent structures (26.7%). Only 16.7% of the conversions were caused by intraoperative medical or surgical complications. Converted patients required longer operative times and developed more postoperative complications, both overall (39.2% versus 27.5%; P = .006) and severe ones (13.3% versus 8.3%; P = .061). Male gender (odds ratio [OR] = 1.89 [95% confidence interval: 1.31–2.71]), obesity (OR = 1.99 [1.4–2.83]), prior abdominal surgery (OR = 1.68 [1.19–2.37]), and pT4 cancers (OR = 4.04 [2.86–5.69]) were independently associated with conversion. Conversion to open surgery was not significantly associated with tumor recurrence (hazard ratios = 1.395 [0.724–2.687]). Conclusions: Although conversion to open surgery during MIS-RC for cancer is associated with worsened postoperative outcomes, it seems not to impact on the oncologic prognosis. [ABSTRACT FROM AUTHOR]
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- 2023
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21. First worldwide report on Hugo RAS™ surgical platform in right and left colectomy.
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Bianchi, Paolo Pietro, Salaj, Adelona, Rocco, Bernardo, and Formisano, Giampaolo
- Abstract
The diffusion of robotic surgery is rapidly and constantly growing in different surgical specialties. Recently, novel robotic platforms have entered into the market. To date, however, most of the reports on their clinical use have specifically focused on gynecological and urological surgery. In this study, we present the first three robotic-assisted colectomies performed with the new Hugo RAS system (Medtronic, Minneapolis, MN, USA). The surgical team had previous robotic experience and completed simulation training and an official 2-day cadaver laboratory session. Operating room setting and trocar layout were planned and two full cadaver procedures were carried out (right and left colectomy). Onsite dry-run sessions were performed before tackling clinical cases. Three patients underwent robotic-assisted colectomies: one left colectomy, two right colectomies with complete mesocolic excision (CME) and high vascular ligation (HVL) at our Institution. Preoperative diagnosis was colonic adenocarcinoma in all cases. A description of the operative room setup, robotic arm configuration and docking angles is provided. Mean docking time and console time were 8 and 259 min, respectively. All the surgical steps were completed without critical surgical errors or high-priority alarms. Neither intraoperative complications nor conversions to open surgery were recorded. Postoperative courses were uneventful with a mean length of stay of 5 days. Further clinical data and experience are required for procedural standardization and potential integration of the system into robotic general surgery and colorectal programs. [ABSTRACT FROM AUTHOR]
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- 2023
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22. Robotic Right Hemicolectomy: Complete Mesocolic Excision and Intracorporeal Anastomosis
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Gómez Ruiz, Marcos, Cagigas Fernández, Carmen, Suarez Pazos, Natatalia, Coyne, Peter, editor, and Khan, Jim, editor
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- 2022
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23. Robotic versus laparoscopic right colectomy for colon cancer: a systematic review and meta-analysis
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Jian-Chun Zheng, Shuai Zhao, Wei Chen, and Jian-Xiang Wu
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colon cancer ,right colectomy ,robotic ,laparoscopic ,meta-analysis ,Medicine - Published
- 2022
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24. Definition and reporting of lymphadenectomy and complete mesocolic excision for radical right colectomy: a systematic review.
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Sica, Giuseppe S., Vinci, Danilo, Siragusa, Leandro, Sensi, Bruno, Guida, Andrea M., Bellato, Vittoria, García-Granero, Álvaro, and Pellino, Gianluca
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COLECTOMY , *RIGHT-wing extremism , *LYMPHADENECTOMY , *COLON cancer , *DEFINITIONS - Abstract
Background: Several procedures have been proposed to reduce the rates of recurrence in patients with right-sided colon cancer. Different procedures for a radical right colectomy (RRC), including extended D3 lymphadenectomy, complete mesocolic excision and central vascular ligation have been associated with survival benefits by some authors, but results are inconsistent. The aim of this study was to assess the variability in definition and reporting of RRC, which might be responsible for significant differences in outcome evaluation. Methods: PRISMA-compliant systematic literature review to identify the definitions of RRC. Primary aims were to identify surgical steps and different nomenclature for RRC. Secondary aims were description of heterogeneity and overlap among different RRC techniques. Results: Ninety-nine articles satisfied inclusion criteria. Eight surgical steps were identified and recorded as specific to RRC: Central arterial ligation was described in 100% of the included studies; preservation of mesocolic integrity in 73% and dissection along the SMV plane in 67%. Other surgical steps were inconstantly reported. Six differently named techniques for RRC have been identified. There were 35 definitions for the 6 techniques and 40% of these were used to identify more than one technique. Conclusions: The only universally adopted surgical step for RRC is central arterial ligation. There is great heterogeneity and consistent overlap among definitions of all RRC techniques. This is likely to jeopardise the interpretation of the outcomes of studies on the topic. Consistent use of definitions and reporting of procedures are needed to obtain reliable conclusions in future trials. PROSPERO CRD42021241650. [ABSTRACT FROM AUTHOR]
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- 2023
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25. Intracorporeal or extracorporeal ileocolic anastomosis after laparoscopic right colectomy: cost analysis of the Torino trial.
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Seno, Elisabetta, Allaix, Marco Ettore, Ammirati, Carlo Alberto, Bonino, Marco Augusto, Arezzo, Alberto, Mistrangelo, Massimiliano, and Morino, Mario
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COLECTOMY , *COST analysis , *HOSPITAL laboratories , *COLON tumors , *SURGICAL instruments , *LAPAROSCOPIC surgery - Abstract
Background: Intracorporeal (IIA) and extracorporeal anastomosis (EIA) are two well-established techniques for restoration of bowel continuity after laparoscopic right colectomy (LRC). Since no economic analysis comparing the two different anastomotic techniques has been performed yet, it is still unclear if IIA can reduce perioperative costs. The aim of the study was to compare costs of LRC with IIA or EIA for right-sided colon neoplasm. Methods: This is a cost analysis of a single-institution double-blinded randomized controlled trial comparing the outcomes of LRC with IIA and LRC with EIA in patients with a right-sided colon neoplasm. All direct in-hospital costs related to patient's admission were recorded (intraoperative costs: operative room, surgical tools, blood units—postoperative costs: hospital stay, laboratory and microbiology analyses, diagnostic services, analgesic drugs and antibiotic therapy, blood units, reoperation—outpatient costs: post-discharge wound medications). This trial was registered with ClinicalTrials.gov, Number NCT03045107. Results: A total of 140 patients were randomized and analyzed. Mean overall costs in the IIA group exceeded 349 € the mean overall costs of the EIA group (7926.87 ± 4617.23 € vs. 7577.45 ± 6131.17 €; P = 0.704). A mean extra charge of 608 € regarding total intraoperative costs was recorded in the IIA group (3058.84 ± 897.42 € vs. 2450.15 ± 558.90 €; P < 0.001). The cost of surgical instruments resulted in 542 € additional charge per patient in the IIA group compared to EIA group (1782.74 ± 541.26 € vs. 1240.55 ± 384.09 €; P < 0.001). The mean cost of operative room occupancy was comparable in IIA and EIA group: 1276.09 ± 514.94 € vs. 1209.60 ± 422.80 € (P = 0.405). No significant differences were observed in postoperative costs and in outpatient costs. Conclusion: This economic analysis showed that IIA and EIA after LRC had similar overall costs, even though there were intraoperative extra costs of IIA. [ABSTRACT FROM AUTHOR]
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- 2023
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26. Robotic versus laparoscopic right colectomy for colon cancer: a systematic review and meta-analysis.
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Jian-Chun Zheng, Shuai Zhao, Wei Chen, and Jian-Xiang Wu
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COLECTOMY , *COLON cancer , *BLOOD loss estimation , *LYMPHADENECTOMY , *LAPAROSCOPIC surgery , *SURGICAL complications - Abstract
Aim: The aim of the study was to compare the short-term surgical outcomes of robotic right colectomy (RRC) with laparoscopic right colectomy (LRC) for colon cancer, to evaluate the safety and feasibility of the robotic surgery system. Material and methods: A systematic literature review was conducted using the PubMed, Web of Science, Embase, and Cochrane Library databases regarding the comparison of RRC vs. LRC for colon cancer in the last 5 years. Studies were included as per the PICOS criteria, and relevant event data were extracted. Results: Fifteen studies (RRC: 1116 patients; LRC: 4036 patients) were evaluated. RRC demonstrated lower conversion to laparotomy (p = 0.03) and shorter length of hospital stay (p = 0.01), compared with LRC. However, operation times were longer in RRC than in LRC (p < 0.001). The estimated blood loss, retrieved lymph nodes, and overall postoperative complications were similar between RRC and LRC (p > 0.05). Conclusions: RRC can be regarded as a feasible and safe technique for colon cancer. [ABSTRACT FROM AUTHOR]
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- 2023
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27. Laparoscopic Intracorporeal Anastomosis.
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Goldstone, Robert N. and Popowich, Daniel A.
- Abstract
Given the progression of laparoscopic surgery, questions continue to arise as to the ideal technique for a laparoscopic colectomy. The most debated of these questions is whether it is best to complete an intracorporeal (ICA) or extracorporeal (ECA) intestinal anastomosis. Here, we review the literature to date and report the equivalent safety and efficacy of ICA and ECA for laparoscopic right colectomy. However, these studies also indicate that when completed, ICA may prove beneficial with respect to earlier return of bowel function, less postoperative pain, shorter incision length, and reduced risk of wound infections. For this, we present the tips and tricks for completing all forms of laparoscopic ICAs during laparoscopic colectomy. [ABSTRACT FROM AUTHOR]
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- 2023
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28. Robotic Surgery of Colon and Rectum
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Ceccarelli, Graziano and Coratti, Andrea
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robotic surgery ,colorectal cancer ,stoma ,left colectomy ,right colectomy ,surgical oncology ,bic Book Industry Communication::M Medicine::MN Surgery::MNG Gastrointestinal & colorectal surgery ,bic Book Industry Communication::M Medicine::MN Surgery::MNC General surgery - Abstract
This is an open access book. Colorectal surgery is one of the most performed procedures in dedicated colorectal and general surgery units worldwide. In the last two decades, the minimally invasive laparoscopic approach has become very popular worldwide, attracting great interest among patients (lower risk of infection, less pain, and faster recovery) and demonstrating excellent oncological results. Technology is improving rapidly, offering revolutionary innovations, particularly with the advent of robotic surgery, which offers important advantages over laparoscopy for both surgeons and patients: improved ergonomics, wristed instruments, and a better vision. These advantages may be particularly useful for more complex and challenging situations (complete mesocolic excision, low rectal cancer, one-stage treatment of colorectal and liver metastases, etc.), translating into potential improved surgical and oncological results. Although several books have been published on the subject, the great interest in robotic surgery makes it mandatory, in our opinion, to have a general update in view of the latest technical innovations and the results of the most relevant and recent literature. The book is divided into chapters dealing with the different colorectal segments with their robotic surgical operations and specific technical variants. The new frontiers of benign and emergency colorectal diseases are also considered, as well as the new robotic platforms recently introduced in the healthcare market. Some of them, such as the da Vinci SP single port device, may represent a revolutionary approach for this surgery. Training and cost aspects were also considered.
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- 2024
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29. Impact of operation duration on postoperative outcomes of minimally‐invasive right colectomy.
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de'Angelis, Nicola, Schena, Carlo Alberto, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Pecchini, Francesca, Winter, Des C., O'Connell, Lauren, Carcoforo, Paolo, Urbani, Alessia, Aisoni, Filippo, Martínez‐Pérez, Aleix, Celentano, Valerio, Chiarugi, Massimo, Tartaglia, Dario, Coccolini, Federico, Arces, Francesco, Di Saverio, Salomone, Frontali, Alice, Fuks, David, and Denet, Christine
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COLECTOMY , *TREATMENT effectiveness , *SURGICAL complications , *INDOCYANINE green , *ONCOLOGIC surgery , *UNIVARIATE analysis - Abstract
Aim: Operation time (OT) is a key operational factor influencing surgical outcomes. The present study aimed to analyse whether OT impacts on short‐term outcomes of minimally‐invasive right colectomies by assessing the role of surgical approach (robotic [RRC] or laparoscopic right colectomy [LRC]), and type of ileocolic anastomosis (i.e., intracorporal [IA] or extra‐corporal anastomosis [EA]). Methods: This was a retrospective analysis of the Minimally‐invasivE surgery for oncological Right ColectomY (MERCY) Study Group database, which included adult patients with nonmetastatic right colon adenocarcinoma operated on by oncological RRC or LRC between January 2014 and December 2020. Univariate and multivariate analyses were used. Results: The study sample was composed of 1549 patients who were divided into three groups according to the OT quartiles: (1) First quartile, <135 min (n = 386); (2) Second and third quartiles, 135–199 min (n = 731); and (3) Fourth quartile ≥200 min (n = 432). The majority (62.7%) were LRC‐EA, followed by LRC‐IA (24.3%), RRC‐IA (11.1%), and RRC‐EA (1.9%). Independent predictors of an OT ≥ 200 min included male gender, age, obesity, diabetes, use of indocyanine green fluorescence, and IA confection. An OT ≥ 200 min was significantly associated with an increased risk of postoperative noninfective complications (AOR: 1.56; 95% CI: 1.15–2.13; p = 0.004), whereas the surgical approach and the type of anastomosis had no impact on postoperative morbidity. Conclusion: Prolonged OT is independently associated with increased odds of postoperative noninfective complications in oncological minimally‐invasive right colectomy. [ABSTRACT FROM AUTHOR]
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- 2022
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30. Right colectomy from open to robotic — a single-center experience with functional outcomes in a learning-curve setting.
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Hirschburger, Markus, Schneider, Rolf, Kraenzlein, Sophie, Padberg, Winfried, Hecker, Andreas, and Reichert, Martin
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COLECTOMY , *SURGICAL robots , *ROBOTICS , *SURGICAL complications , *FUNCTIONAL status , *PATIENT safety - Abstract
Purpose: Right colectomy (RC) is a frequently performed procedure. Beneath standard conventional open surgery (COS), various minimally invasive techniques had been introduced. Several advantages had recently been described for robotic approaches over COS or conventional laparoscopy. Nevertheless, novel minimally invasive techniques require continuous benchmarking against standard COS to gain maximum patient safety. Bowel dysfunction is a frequent problem after RC. Together with general complication rates postoperative bowel recovery are used as surrogate parameters for postoperative patient outcome in this study. Methods: Retrospective, 10-year single-center analysis of consecutive patients who underwent sequentially either COS (n = 22), robotic-assisted (ECA: n = 39), or total robotic surgery (ICA: n = 56) for oncologic RC was performed. Results: The conversion from robotic to open surgery rate was low (overall: 3.2%). Slightly longer duration of surgery had been observed during the early phase after introduction of the robotic program to RC (ECA versus COS, p = 0.044), but not anymore thereafter (versus ICA). No differences were observed in oncologic parameters including rates of tumor-negative margins, lymph node-positive patients, and lymph node yield during mesocolic excision. Both robotic approaches are beneficial regarding postoperative complication rates, especially wound infections, and shorter length of in-hospital stay compared with COS. The duration until first postoperative stool is the shortest after ICA (COS: 4 [2–8] days, ECA: 3 [1–6] days, ICA: 3 [1–5] days, p = 0.0004). Regression analyses reveal neither a longer duration of surgery nor the extent of mesocolic excision, but the degree of minimally invasiveness and postoperative systemic inflammation contribute to postoperative bowel dysfunction, which prolongs postoperative in-hospital stay significantly. Conclusion: The current study reflects the institutional learning curve of oncologic RC during implementation of robotic surgery from robotic-assisted to total robotic approach without compromises in oncologic results and patient safety. However, the total robotic approach is beneficial regarding postoperative bowel recovery and general patient outcome. [ABSTRACT FROM AUTHOR]
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- 2022
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31. Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis.
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Zarnescu, Eugenia Claudia, Zarnescu, Narcis Octavian, Sanda, Nicoleta, and Costea, Radu
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PREOPERATIVE risk factors ,SURGICAL complications ,COLECTOMY ,LOGISTIC regression analysis ,COLON cancer ,BLOOD transfusion - Abstract
Background and Objectives: This study aimed to investigate the potential risk factors for severe postoperative complications after oncologic right colectomy. Materials and Methods: All consecutive patients with right colon cancer who underwent right colectomy in our department between 2016 and 2021 were retrospectively included in this study. The Clavien–Dindo grading system was used to evaluate postoperative complications. Univariate and multivariate logistic regression analyses were used to investigate risk factors for postoperative severe complications. Results: Of the 144 patients, there were 69 males and 75 females, with a median age of 69 (IQR 60–78). Postoperative morbidity and mortality rates were 41.7% (60 patients) and 11.1% (16 patients), respectively. The anastomotic leak rate was 5.3% (7 patients). Severe postoperative complications (Clavien–Dindo grades III–V) were present in 20 patients (13.9%). Univariate analysis showed the following as risk factors for postoperative severe complications: Charlson score, lack of mechanical bowel preparation, level of preoperative proteins, blood transfusions, and degree of urgency (elective/emergency right colectomy). In the logistic binary regression, the Charlson score (OR = 1.931, 95% CI = 1.077–3.463, p = 0.025) and preoperative protein level (OR = 0.049, 95% CI = 0.006–0.433, p = 0.007) were found to be independent risk factors for postoperative severe complications. Conclusions: Severe complications after oncologic right colectomy are associated with a low preoperative protein level and a higher Charlson comorbidity index. [ABSTRACT FROM AUTHOR]
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- 2022
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32. Novel nomogram for predicting risk of early postoperative small bowel obstruction after right colectomy for cancer
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Huida Zheng, Yurong Liu, Zhenze Chen, Yafeng Sun, and Jianhua Xu
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Nomogram ,Right colectomy ,Early postoperative small bowel obstruction ,Risk factors ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Early postoperative small bowel obstruction (EPSBO) is a common complication after colorectal cancer surgery. Few studies have specifically studied risk factors for early small bowel obstruction after right colectomy, especially in establishing predictive models. The purpose of the current study was to establish an effective nomogram to predict the incidence of EPSBO after right colectomy. Methods The current study retrospectively analyzed data from a total of 424 patients who underwent right colectomy in a local hospital from January 2014 to March 2021. A logistic regression model was used to identify potential risk factors for EPSBO after right colectomy. A nomogram was established by independent risk factors, and the prediction performance of the model was evaluated using an area under the receiver operating characteristic (ROC) curve and calibration chart. Results A total of 45 patients (10.6%) developed early small bowel obstruction after right colectomy. Male sex, emergency operation, history of abdominal surgery, open surgery, long operative time, anastomotic leakage, and preoperative albumin were closely related to EPSBO. Analysis of postoperative rehabilitation indices showed that EPSBO remarkably slowed the postoperative rehabilitation speed of patients. Multivariate logistic regression analysis showed that male sex, open surgery, operative time, and anastomotic leakage were independent risk factors (P < 0.05), and the operation time had the greatest impact on EPSBO. On the basis of multivariate logistic regression, a nomogram was constructed, which showed moderate accuracy in predicting EPSBO, with a C-statistic of 0.716. The calibration chart showed good consistency between the predicted probability and ideal probability. Conclusion The current study constructed a nomogram based on the clinical data of patients who underwent right colectomy, which had moderate predictability and could provide reference value for clinicians to evaluate the risk of EPSBO.
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- 2022
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33. Robotic Right Colectomy with Complete Mesocolic Excision and Intracorporeal Anastomosis
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Keshinro, Ajaratu, Ali, Fadwa, Weiser, Martin R., Patti, Marco G., editor, Zureikat, Amer H., editor, Fichera, Alessandro, editor, and Schlottmann, Francisco, editor
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- 2021
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34. Single Site: Historical Perspectives and Current Application
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Spinoglio, Giuseppe, Mellano, Alfredo, Conte, Domenico Lo, Ribero, Dario, Gharagozloo, Farid, editor, Patel, Vipul R., editor, Giulianotti, Pier Cristoforo, editor, Poston, Robert, editor, Gruessner, Rainer, editor, and Meyer, Mark, editor
- Published
- 2021
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35. Robotic Colectomy with CME
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Spinoglio, Giuseppe, Petz, Wanda, Bertani, Emilio, Ribero, Dario, Gharagozloo, Farid, editor, Patel, Vipul R., editor, Giulianotti, Pier Cristoforo, editor, Poston, Robert, editor, Gruessner, Rainer, editor, and Meyer, Mark, editor
- Published
- 2021
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36. Minimally Invasive Right Colectomy: Extracorporeal Versus Intracorporeal Anastomosis
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Gómez Ruiz, Marcos, Gómez Fleitas, Manuel, Gharagozloo, Farid, editor, Patel, Vipul R., editor, Giulianotti, Pier Cristoforo, editor, Poston, Robert, editor, Gruessner, Rainer, editor, and Meyer, Mark, editor
- Published
- 2021
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37. Pattern of recurrence and survival after D2 right colectomy for cancer: is there place for a routine more extended lymphadenectomy?
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Palmeri, Matteo, Peri, Andrea, Pucci, Valentina, Furbetta, Niccolò, Gallo, Virginia, Di Franco, Gregorio, Pagani, Anna, Dauccia, Chiara, Farè, Camilla, Gianardi, Desirée, Guadagni, Simone, Bianchini, Matteo, Comandatore, Annalisa, Masi, Gianluca, Cremolini, Chiara, Borelli, Beatrice, Pollina, Luca Emanuele, Di Candio, Giulio, Pietrabissa, Andrea, and Morelli, Luca
- Abstract
Background: Conventional Right Colectomy with D2 lymphadenectomy (RC-D2) currently represent the most common surgical treatment of right-sided colon cancer (RCC). However, whether it should be still considered a standard of care, or replaced by a routine more extended D3 lymphadenectomy remains unclear. In the present study, we aim to critically review the patterns of relapse and the survival outcomes obtained from our 11-year experience of RC-D2. Methods: Clinical data of 489 patients who underwent RC-D2 for RCC at two centres, from January 2009 to January 2020, were retrospectively reviewed. Patients with synchronous distant metastases and/or widespread nodal involvement at diagnosis were excluded. Post-operative clinical–pathological characteristics and survival outcomes were evaluated including the pattern of disease relapse. Results: We enrolled a total of 400 patients with information follow-up. Postoperative morbidity was 14%. The median follow-up was 62 months. Cancer recurrence was observed in 55 patients (13.8%). Among them, 40 patients (72.7%) developed systemic metastases, and lymph-node involvement was found in 7 cases (12.8%). None developed isolated central lymph-node metastasis (CLM), in the D3 site. The estimated 3- and 5-year relapse-free survival were 86.1% and 84.4%, respectively. The estimated 3- and 5-year cancer-specific OS were 94.5% and 92.2%, respectively. Conclusions: The absence of isolated CLM, as well as the cancer-specific OS reported in our series, support the routine use of RC-D2 for RCC. However, D3 lymphadenectomy may be recommended in selected patients, such as those with pre-operatively known CLM, or with lymph-node metastases close to the origin of the ileocolic vessels. [ABSTRACT FROM AUTHOR]
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- 2022
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38. Minimally invasive right versus left colectomy for cancer: does robotic surgery mitigate differences in short-term outcomes?
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Nasseri, Yosef, Kasheri, Eli, Oka, Kimberly, Cox, Brian, Cohen, Jason, Ellenhorn, Joshua, and Barnajian, Moshe
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Studies comparing right (RC) and left colectomies (LC) show higher rates of ileus in RC and higher wound infection and anastomotic leak rates in LC. However, prior studies did not include robotic procedures. We compared short-term outcomes of laparoscopic and robotic RC and LC for cancer, with sub-analysis of robotic procedures. In a retrospective review of a prospective database, preoperative factors, intraoperative events, and 30-day postoperative outcomes were compared. Student's t tests and Chi-square tests were used for continuous and categorical variables, respectively. A logistic binomial regression was performed to assess whether type of surgery was associated with postoperative complications. Between January 2014 and August 2020, 115 patients underwent minimally invasive RC or LC for cancer. Sixty-eight RC [30 (44.1%) laparoscopic, 38 (55.9%) robotic] and 47 LC [13 (27.6%) laparoscopic, 34 (72.4%) robotic] cases were included. On univariate analysis, RC patients had significantly higher overall postoperative complications but no differences in rates of ileus/small bowel obstruction, wound infection, time to first flatus/bowel movement, length of hospital stay, and 30-day readmissions. On multivariate analysis, there was no significant difference in overall complications and laparoscopic surgery had a 2.5 times higher likelihood of complications than robotic surgery. In sub-analysis of robotic cases, there was no significant difference among all outcome variables. Previously reported outcome differences between laparoscopic RC and LC for cancer may be mitigated by robotic surgery. [ABSTRACT FROM AUTHOR]
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- 2022
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39. A multicentre, prospective cohort study of handsewn versus stapled intracorporeal anastomosis for robotic hemicolectomy.
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Harji, Deena, Rouanet, Philippe, Cotte, Eddy, Dubois, Anne, Rullier, Eric, Pezet, Denis, Passot, Guillaume, Taoum, Christophe, and Denost, Quentin
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HEMICOLECTOMY , *RIGHT hemicolectomy , *COHORT analysis , *LONGITUDINAL method , *ROBOTICS , *COLECTOMY - Abstract
Aim: Robotic right hemicolectomy is gaining in popularity due to the recognized technical benefits associated with the robotic platform. However, there is a lack of standardization regarding the optimal anastomotic technique in this cohort of patients, namely stapled or handsewn intra‐ or extra‐corporeal anastomosis. The ergonomic benefit associated with the robotic platform lends itself to intracorporeal anastomosis (ICA). The aim of this study was to compare the short‐term clinical outcomes of stapled versus handsewn ICA. Method: A multicentre prospective cohort study was undertaken across four high‐volume robotic centres in France between September 2018 and December 2020. All adult patients undergoing an elective robotic right hemicolectomy with an ICA performed and a minimum postoperative follow‐up of 30 days were included. The primary endpoint of our study was anastomotic leak within 30 days postoperatively. Results: A total of 144 patients underwent robotic right hemicolectomy: 92 (63.8%) had a stapled ICA and 52 (36.1%) a handsewn ICA. The operative indication was adenocarcinoma in 90% with a stapled ICA compared with 62% in the handsewn ICA group (p < 0.001). The overall operating time was longer in the handsewn ICA group compared with the stapled ICA group (219 min vs. 193 min; p = 0.001). The anastomotic leak rate was 3.3% in stapled ICA and 3.8% in handsewn ICA (p = 1.00). There was no difference in the rate or severity of postoperative morbidity. Conclusion: ICA robotic hemicolectomy is technically safe and is associated with low rates of anastomotic leak overall and equivalent clinical outcomes between the two techniques. [ABSTRACT FROM AUTHOR]
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- 2022
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40. Short-term outcomes of intracorporeal and extracorporeal anastomosis in robotic right colectomy: a systematic review and meta-analysis.
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Liang, Y., Li, L., Su, Q., Liu, Y., Yin, H., and Wu, D.
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COLECTOMY , *RIGHT hemicolectomy , *SURGICAL anastomosis , *ROBOTICS , *CRIME & the press , *ODDS ratio , *CONFIDENCE intervals - Abstract
Ileocolic anastomosis is performed via extracorporeal or intracorporeal techniques in robotic right hemicolectomy. The aim of this meta-analysis was to compare the short-term outcomes of intracorporeal anastomosis (IA) and extracorporeal anastomosis (EA) for robotic right colectomy. The EMBASE, PubMed, and Cochrane Library databases were searched systematically (from inception until March 1, 2020) for randomized and non-randomized control trials reporting the short-term outcomes of IA and EA for robotic right colectomy. Five observational cohort studies involving 585 participants were included in our meta-analysis. Compared to the EA group, the IA group showed significantly longer operation time [weighted mean difference (WMD): 28.88, 95% confidence interval (CI) 13.88–43.89, p = 0.0002], lower rate of anastomotic leak (odds ratio: 0.26, 95% CI 0.08–0.85, p = 0.03), and shorter time to first flatus (WMD: − 0.57, 95% CI − 0.95 to 0.19, p = 0.003). However, pooled results revealed no difference in blood loss, complications, wound infection, incisional hernia, length of incision, and hospital stay between the IA and EA groups (p < 0.05). This meta-analysis indicated that IA was superior to EA in terms of anastomotic leak and time to first flatus, but inferior in terms of operation time. Large-scale, multicenter, randomized studies are needed to confirm our findings. [ABSTRACT FROM AUTHOR]
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- 2022
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41. Objective Performance Indicators During Robotic Right Colectomy Differ According to Surgeon Skill.
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Gillani M, Rupji M, Paul Olson TJ, Sullivan P, Shaffer VO, Balch GC, Shields MC, Liu Y, and Rosen SA
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Introduction: Surgeon assessment tools are subjective and nonscalable. Objective performance indicators (OPIs), machine learning-enabled metrics recorded during robotic surgery, offer objective insights into surgeon movements and robotic arm kinematics. In this study, we identified OPIs that significantly differed across expert (EX), intermediate (IM), and novice (NV) surgeons during robotic right colectomy., Methods: Endoscopic videos were annotated to delineate 461 surgical steps across 25 robotic right colectomies. OPIs were compared among two EX, two IM, and eight NV surgeons during mesenteric dissection, vascular pedicle ligation, right colon and hepatic flexure mobilization, and preparation of the proximal and distal bowel for transection., Results: Compared to NV's, EX's exhibited greater velocity, acceleration and jerk for camera, dominant, nondominant, and third arms across all steps. Compared to NV's, IM's exhibited more arm swaps and master clutch use, higher camera-related metrics (movement, path length, moving time, velocity, acceleration, and jerk), greater dominant wrist pitch and nondominant wrist articulations (roll, pitch, and yaw), longer dominant and nondominant arm path length, and higher velocity, acceleration and jerk for dominant, nondominant, and third arms across all steps. Compared to NV's, EX/IM surgeons utilized more arm swaps, higher camera-related metrics (movement, path length, velocity, acceleration, and jerk), longer nondominant arm path length, and greater velocity, acceleration and jerk for dominant, nondominant, and third arms across all steps., Conclusions: We report OPIs that discriminate EX, IM, and NV surgeons during RRC. This study is the first to demonstrate feasibility of using OPIs as an objective, scalable way to classify surgeon skill during RRC steps., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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42. Comparison of conventional resection to D3 lymphadenectomy in right-sided colon cancer: A retrospective cohort study.
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Raje P, Sonal S, Kunitake H, Berger DL, Lee GC, Ricciardi R, Morita S, Shigeta K, Okabayashi K, and Goldstone RN
- Abstract
Background: Lymphadenectomy during right hemicolectomy for colon cancer varies between the U.S. and Japan., Methods: Patients undergoing right hemicolectomy for non-metastatic right-sided colon cancer between 2010 and 2019 at U.S. and Japanese institutions were compared. Outcomes included survival, pathologic findings, and postoperative complications., Results: 319 American patients (57 % female, mean age 70 years) underwent conventional resection and 308 Japanese patients (52 % female, mean age 70 years) underwent extended dissection. The conventional group underwent more laparotomies (26.6 % vs. 8.4 %, p < 0.001), had more poorly differentiated histology (31.7 % vs. 11.0 %, p < 0.01), lower lymph node yield (M = 27 ± 11 vs. M = 32 ± 14, p < 0.001), and more 30-day readmissions (31 vs. 5, p < 0.001). Adjusting for demographics, pathology, perioperative outcomes, and adjuvant chemotherapy, extended lymphadenectomy improved disease-free survival (HR 0.50; 95 % CI, 0.31-0.80; p = 0.004), but not overall survival (HR 0.98; 95 % CI, 0.95-1.02; p = 0.14)., Conclusions: Extended lymphadenectomy for right sided-colon cancer improves disease-free, but not overall, survival among Japanese patients., Competing Interests: Declaration of competing interest The authors report no proprietary or commercial interest in any product mentioned or concept discussed in this article. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors confirm that this manuscript has not been published elsewhere and is not under consideration by another journal., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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43. Advanced Laparoscopic Right Colectomy Techniques for Crohn’s and Reoperative Surgery
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Greenstein, Alexander John, Salky, Barry, Sylla, Patricia, editor, Kaiser, Andreas M., editor, and Popowich, Daniel, editor
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- 2020
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44. Robotic Right-Sided Colon Resection: Unique Considerations and Optimal Setup
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Umanskiy, Konstantin, Sylla, Patricia, editor, Kaiser, Andreas M., editor, and Popowich, Daniel, editor
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- 2020
- Full Text
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45. Laparoscopic Right Colectomy for Malignant Disease
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Kessler, Hermann, Lipman, Jeremy M., Sylla, Patricia, editor, Kaiser, Andreas M., editor, and Popowich, Daniel, editor
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- 2020
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46. Masters Program Colorectal Pathway: Laparoscopic Right Colectomy for Benign Disease
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Young-Fadok, Tonia M., Sylla, Patricia, editor, Kaiser, Andreas M., editor, and Popowich, Daniel, editor
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- 2020
- Full Text
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47. Da Vinci SP robotic approach to colorectal surgery: two specific indications and short-term results.
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Piozzi, G. N., Kim, J.-S., Choo, J. M., Shin, S. H., Kim, J. S., Lee, T.-H., Baek, S.-J., Kwak, J.-M., Kim, J., and Kim, S. H.
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PROCTOLOGY , *SURGICAL margin , *BLOOD loss estimation , *COLECTOMY , *LYMPHADENECTOMY , *CROHN'S disease , *CHEMORADIOTHERAPY - Abstract
Background: Da Vinci® Single Port (dvSP) was recently developed. Its application in colorectal surgery is under investigation. The aim of this study was to explore the safety and feasibility of dvSP for intersphincteric (dvSP-ISR), right colectomy (dvSP-RC), and transverse colectomy (dvSP-TC). Surgical indication and short-term results were analyzed. Methods: All consecutive patients from a prospective database of patients who underwent dvSP-ISR, dvSP-RC, and dvSP-TC at Korea University Anam Hospital from November 2020 to December 2021, were analyzed. Perioperative, pathological, and oncological short-term outcomes were analyzed. Results: A total of 7 dvSP-ISR, 5 dvSP-RC, and 1 dvSP-TC were performed. Median age was 56.0 (55.0–61.0) years for the dvSP-ISR and 54.0 (44.7–63.5) years for the dvSP-RC/TC. Median body mass index was 22.8 (17.1–24.8) kg/m2 for the dvSP-ISR and 23.6 (20.8–26.9) kg/m2 for the dvSP-RC/TC. All dvSP-ISR patients received neoadjuvant long-course chemoradiotherapy, including one patient with squamocellular carcinoma who was treated with 5-fluorouracil (5-FU)/mitomycin. All other patients, excluding one dvSP-RC patient with Crohn's disease, had an adenocarcinoma. Median operation time was 280 (240–370) minutes for the dvSP-ISR and 220 (201–270) minutes for the dvSP-RC/TC. Estimated blood loss was insignificant. No intraoperative complications or conversions to multiport/open surgery was reported. Median post-operative stay was 7.0 (6.0–10.0) days for the dvSP-ISR and 5.0 (4.0–6.7) days for the dvSP-RC/TC. Quality of mesorectum was complete for six patients, and nearly complete for one. Median number of retrieved lymph nodes were 21 (17–25) for the dvSP-ISR and 28 (24–49) for the dvSP-RC/TC. Proximal and distal resection margins were tumor free. Four patients experienced post-operative complications not related to the platform which were: ileus, voiding dysfunction, infected pelvic hematoma, and wound infection. Median follow-up was 9 (6–11) months and 11 (7–17) months for the dvSP-ISR and dvSP-RC/TC, respectively. Two patients had systemic recurrence; all others were tumor free. Conclusions: The dvSP platform is safe and feasible for intersphincteric resection with right lower quadrant access, and right/transverse colectomy with suprapubic access. Further studies are needed to evaluate benefit differences compared to multiport robotic platform. [ABSTRACT FROM AUTHOR]
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- 2022
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48. Robotic-assisted right colectomy. Official expert recommendations delivered under the aegis of the French Association of Surgery (AFC).
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de'Angelis, N., Micelli Lupinacci, R., Abdalla, S., Genova, P., Beliard, A., Cotte, E., Denost, Q., Goasguen, N., Lakkis, Z., Lelong, B., Manceau, G., Meurette, G., Perrenot, C., Pezet, D., Rouanet, P., Valverde, A., and Pessaux, P.
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COLECTOMY ,MINIMALLY invasive procedures ,PROGRESSION-free survival ,SURGERY ,ABDOMINAL surgery ,OVERALL survival - Abstract
Twenty-seven experts under the aegis of the French Association of Surgery (AFC) offer this reference system with formalized recommendations concerning the performance of right colectomy by robotic approach (RRC). For RRC, experts suggest patient installation in the so-called "classic" or "suprapubic" setup. For patients undergoing right colectomy for a benign pathology or cancer, RRC provides no significant benefit in terms of intra-operative blood loss, intra-operative complications or conversion rate to laparotomy compared to laparoscopy. At the same time, RRC is associated with significantly longer operating times. Data from the literature are insufficient to define whether the robot facilitates the performance of an intra-abdominal anastomosis, but the robotic approach is more frequently associated with an intra-abdominal anastomosis than the laparoscopic approach. Experts also suggest that RRC offers a benefit in terms of post-operative morbidity compared to right colectomy by laparotomy. No benefit is retained in terms of mortality, duration of hospital stay, histological results, overall survival or disease-free survival in RRC performed for cancer. In addition, RRC should not be performed based on the cost/benefit ratio, since RRC is associated with significantly higher costs than laparoscopy and laparotomy. Future research in the field of RRC should consider the evaluation of patient-targeted parameters such as pain or quality of life and the technical advantages of the robot for complex procedural steps, as well as surgical and oncological results. [ABSTRACT FROM AUTHOR]
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- 2022
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49. Laparoscopic right colectomy: changes in surgical technique and perioperative management allow better postoperative results in a comparative series of 361 patients.
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Grieco, Michele, Marcellinaro, Rosa, Spoletini, Domenico, Menditto, Rosa, Lisi, Giorgio, Russo, Giulia, Napoleone, Vincenzo, and Carlini, Massimo
- Abstract
To compare the short-term outcomes in patients who underwent laparoscopic right colectomy with a traditional minimally invasive approach versus patients who underwent a laparoscopic colectomy with an enhanced perioperative pathway. A retrospective analysis was conducted on a consecutive series of patients who underwent elective laparoscopic right colectomy for neoplastic disease between January 1, 2011 and December 31, 2020. The patients were divided into two groups: the first cohort (FC), who underwent a traditional laparoscopic colectomy, mainly with extracorporeal anastomosis, between January 1, 2011 and December 31, 2015 and the second cohort (SC), who underwent a laparoscopic colectomy with an enhanced intraoperative (intracorporeal anastomosis) and perioperative pathway (ERAS protocol) between January 1, 2016 and December 31, 2020. There were a total of 361 patients, including 177 in the FC and 184 in the SC. In the SC a higher number of intracorporeal anastomoses was performed (91.8% vs. 19.2%, p < 0.001), drains were placed in 42 patients only (22.8% vs. 100% in the FC) and nasogastric tubes were placed in 21 patients only (11.4% vs. 100% in the FC). In the initial period of the SC. the procedures required a slightly longer operative time (median 105 vs. 95 min; p = 0.002), but postoperative surgical complications were lower (12% vs. 17.4%, p = 0.179). Postoperative recovery was faster in SC along with time to discharge (4 vs. 7 days; p < 0.001). Intraoperative anastomosis and enhanced pathways in right laparoscopic colectomy seem to guarantee better results with lower surgical complications and faster postoperative recovery. [ABSTRACT FROM AUTHOR]
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- 2022
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50. Right colectomy with intracorporeal anastomosis for cancer: a prospective comparison between robotics and laparoscopy.
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Sorgato, Nadia, Mammano, Enzo, Contardo, Tania, Vittadello, Fabrizio, Sarzo, Giacomo, and Morpurgo, Emilio
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Robotics in right colectomy are still under debate. Available studies compare different techniques of ileocolic anastomosis but results are non-conclusive. Our study aimed to compare intraoperative outcomes, and short-term postoperative results between robotic and standard laparoscopic right colectomies for cancer with intracorporeal anastomosis (ICA) fashioned with the same technique. All consecutive patients scheduled for laparoscopic or robotic right hemicolectomies with ICA for cancer in two hospitals, one of which is a tertiary care centre, were prospectively enrolled in our prospective observational study, from April 2018 to December 2019. ICA was fashioned with the same stapled hand-sewn technique. Continuous and categorical variables were analysed using t test and chi-squared test as required. Statistical significance was set at p < 0.05. Forty patients underwent laparoscopic surgery, and 48 underwent robotic right colectomy and were included in the intention-to-treat analysis. Operative time was not statistically different between the two groups (robotic group 265.9 min vs laparoscopic group 254.2 min, p = 0.29). The robotic group had a significantly shorter time for stump oversewing (ileum reinforcement: robotic group 9.3 min vs laparoscopic group 14.2 min, p < 0.001; colon reinforcement: robotic 7.7. min, laparoscopy 13.9 min, p < 0.001) and for ICA (robotic 31.6 min vs laparoscopy 43.0, p < 0.001). One patient underwent extracorporeal anastomosis in the robotic group. The short-term outcomes were comparable between standard laparoscopic and robotic right colectomies with ICA. The limitation of the study is its small sample size and the fact that it was done in two institutions under the supervision of one person. Our data demonstrate that intracorporeal ileocolic anastomosis is safe, and faster and easier with robotic systems. Robotics can facilitate more challenging ICA in minimally invasive surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
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