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263 results on '"Riedl, Claus"'

8. Urodynamics in BPS

Author

Irwin, Paul P., Riedl, Claus, Nordling, Jørgen, editor, Wyndaele, Jean Jacques, editor, van de Merwe, Joop P., editor, Bouchelouche, Pierre, editor, Cervigni, Mauro, editor, and Fall, Magnus, editor

Published
2013
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13. Harnleiterkonkremente bei achtzig und neunzigjährigen Patienten: Aktuelles Therapiemanagement im hospitalisierten Setting

Author

Drerup, Martin, Özsoy, Mehmet, Wehrberger, Clemens, Lenz, Matthias, Stolzlechner, Philipp, Zanier, Johannes, Falkensammer, Claudia, Handjev, Ivan, Ramesmayer, Christian, Riedl, Claus, Wasserscheid, Andreas, and Seklehner, Stephan

Subjects
ddc: 610, Medicine and health
Abstract

Ziel der Arbeit: Die Erfassung der aktuellen Therapie bei achtzig und neunzigjährigen Patienten mit Harnleiterkonkrementen. Material und Methoden: Untersucht wurden Patienten >80 Jahren mit einer Hospitalisierung aufgrund von Harnleiterkonkrementen. Patientendaten wurden aus acht österreichischen [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022

19. Diagnostic Criteria, Classification, and Nomenclature for Painful Bladder Syndrome/Interstitial Cystitis: An ESSIC Proposal

Author

van de Merwe, Joop P., Nordling, Jørgen, Bouchelouche, Pierre, Bouchelouche, Kirsten, Cervigni, Mauro, Daha, L. Kurosch, Elneil, Suzy, Fall, Magnus, Hohlbrugger, Gero, Irwin, Paul, Mortensen, Svend, van Ophoven, Arndt, Osborne, John L., Peeker, Ralph, Richter, Benedikte, Riedl, Claus, Sairanen, Jukka, Tinzl, Martina, and Wyndaele, Jean-Jacques

Published
2008
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24. hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics

Author

Wieser, Matthias, Stadler, Guido, Jennings, Paul, Pfaller, Berthold Streube Walter, Ambros, Peter, Riedl, Claus, Katinger, Hermann, Grillari, Johannes, and Grillari-Voglauer, Regina

Subjects
Epithelial cells -- Properties, Kidney tubules -- Properties, Cell physiology -- Research, Biological sciences
Abstract

Telomere-dependent replicative senescence is one of the mechanisms that limit the number of population doublings of normal human cells. By overexpression of telomerase, cells of various origins have been successfully immortalized without changing the phenotype. While a limited number of telomerase-immortalized cells of epithelial origin are available, none of renal origin has been reported so far. Here we have established simple and safe conditions that allow serial passaging of renal proximal tubule epithelial cells (RPTECs) until entry into telomere-dependent replicative senescence. As reported for other cells, senescence of RPTECs is characterized by arrest in GI phase, shortened telomeres, staining for senescence-associated [beta]-galactosidase, and accumulation of [gamma]-H2AX foci. Furthermore, ectopic expression of the catalytic subunit of telomerase (TERT) was sufficient to immortalize these cells. Characterization of immortalized RPTEC/TERT1 cells shows characteristic morphological and functional properties like formation of tight junctions and domes, expression of aminopeptidase N, cAMP induction by parathyroid hormone, sodium-dependent phosphate uptake, and the megalin/cubilin transport system. No genomic instability within up to 90 population doublings has been observed. Therefore, these cells are proposed as a valuable model system not only for cell biology but also for toxicology, drug screening, biogerontology, as well as tissue engineering approaches. renal proximal tubule cell; renal cell biology; immortalization

Published
2008

30. Two Cases of Strictures after Percutaneous CT-Guided Radiofrequency Ablation for Renal Cell Carcinoma

Author

Heißler, Ortwin, Seklehner, Stephan, Fingernagel, Maximilian, Engelhardt, Paul F., and Riedl, Claus

Subjects
Article Subject
Abstract

Percutaneous radiofrequency ablation is a safe and effective minimally invasive treatment option in selected patients with T1a tumors of the kidney with a low complication rate. We describe two cases that developed the rare but severe complication of thermal injury-induced strictures of the upper urinary tract and its consecutive management.

Published
2020
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35. Invasive therapy for bladder pain syndrome/interstitial cystitis (BPS/IC)

Author

Riedl, Claus

Subjects
Urology, 610 Medical sciences, Medicine
Abstract

This chapter summarizes our present experience with invasive regimen in BPS/IC therapy. A broad spectrum of interventions including simple endoscopic procedures as well as extensive surgery are performed in this indication. Hydrodistension, fulguration of Hunner’s lesions, sacral neuromodulation and cystectomy may all give significant symptom relief to BPS/IC patients, however, the efficacy is not perfectly predictable. Thus, patient selection is crucial, and our algorithms for precise selection of patients for each procedure still are improvable., Chapter of Living Handbook Urogenital Infections and Inflammations

Published
2018
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36. Overactive bladder symptoms in patients undergoing rigid and flexible cystoscopy

Author

Saratlija Novakovic, Zana, primary, Puljak, Livia, additional, Sapunar, Damir, additional, Remzi, Mesut, additional, Fajkovic, Harun, additional, Resch, Irene, additional, Abufaraj, Mohammad, additional, Riedl, Claus, additional, Engelhardt, Paul, additional, Hübner, Wilhelm, additional, Breinl, Eckart, additional, Duvnjak, Mario, additional, and Seklehner, Stephan, additional

Published
2019
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47. A systematic review and meta-analysis on the efficacy of intravesical therapy for bladder pain syndrome/interstitial cystitis

Author

Barua, Jayanta M, Arance, Ignacio, Angulo, Javier C, and Riedl, Claus R

Subjects
Adult, Male, Clinical Trials as Topic, Administration, Intravesical, Treatment Outcome, Interstitial cystitis, Hyaluronic acid, Intravesical instillation, Cystitis, Interstitial, Humans, Female, Bladder pain syndrome
Abstract

Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease characterised by persistent irritating micturition symptoms and pain. The objective was to compare the clinical efficacy of currently available products for intravesical therapy of BPS/IC and to assess their pharmacoeconomic impact. A Pubmed/Medline database search was performed for articles on intravesical therapy for BPS/IC. A total of 345 publications were identified, from which 326 were excluded. Statistical evaluation was performed with effect size (ES) assessment of symptom reduction and response rates. The final set of 19 articles on intravesical BPS/IC therapy included 5 prospective controlled trials (CTs), the remaining were classified as uncontrolled clinical studies. The total number of patients included was 801, 228 of whom had been evaluated in a CT. For CTs, the largest ES for symptom reduction as well as response rate was observed for high molecular weight hyaluronic acid (HMW-HA), with similar findings in two uncontrolled studies with HMW-HA. The number needed to treat to achieve a response to intravesical therapy was 2.67 for intravesical pentosan polysulphate and 1.31 for HMW-HA which were superior to all other instillates. HMW-HA was significantly superior in cost effectiveness and cost efficacy to all other instillation regimes. The present meta-analysis combined medical and pharmacoeconomic aspects and demonstrated an advantage of HMW-HA over other instillation agents; however, direct comparisons between the different products have not been performed to date in properly designed controlled studies.

Published
2016

48. GAG replenishment therapy for bladder pain syndrome/interstitial cystitis.

Author

Wyndaele, Jean Jacques J, Riedl, Claus, Taneja, Rajesh, Lovász, Sándor, Ueda, Tomohiro, and Cervigni, Mauro

Abstract

Aims: To present a rationale for the inclusion of urothelial coating dysfunction in the etipathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC) and the preclinical and clinical evidence in support of glycosaminoglycan (GAG) replenishment therapy in the treatment of BPS/IC, supplemented by the clinical experience of medical experts in the field and patient advocates attending a symposium on GAG replenishment at ESSIC'17, the annual Meeting of the International Society for the Study of Bladder Pain Syndrome, held in Budapest, Hungary in 2017. Results: The urothelial GAG layer has a primary role in providing a permeability barrier to prevent penetration of urinary toxins and pathogens into the bladder wall. Disruption of the GAG layer contributes to the development of BPS/IC. The evidence shows that replenishment of GAGs can restore the GAG layer in BPS/IC, reducing inflammation, pain, and other symptoms. Conclusions: Although data from large randomized controlled studies are limited, long clinical observation and the experience of clinicians and patients support the beneficial effects of intravesical GAG replenishment therapy for providing symptomatic relief for patients with BPS/IC. [ABSTRACT FROM AUTHOR]

Published
2019
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