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2. Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies

Author

Stegmann, Jil D., Kalanithy, Jeshurun C., Dworschak, Gabriel C., Ishorst, Nina, Mingardo, Enrico, Lopes, Filipa M., Ho, Yee Mang, Grote, Phillip, Lindenberg, Tobias T., Yilmaz, Öznur, Channab, Khadija, Seltzsam, Steve, Shril, Shirlee, Hildebrandt, Friedhelm, Boschann, Felix, Heinen, André, Jolly, Angad, Myers, Katherine, McBride, Kim, Bekheirnia, Mir Reza, Bekheirnia, Nasim, Scala, Marcello, Morleo, Manuela, Nigro, Vincenzo, Torella, Annalaura, Pinelli, Michele, Capra, Valeria, Accogli, Andrea, Maitz, Silvia, Spano, Alice, Olson, Rory J., Klee, Eric W., Lanpher, Brendan C., Jang, Se Song, Chae, Jong-Hee, Steinbauer, Philipp, Rieder, Dietmar, Janecke, Andreas R., Vodopiutz, Julia, Vogel, Ida, Blechingberg, Jenny, Cohen, Jennifer L., Riley, Kacie, Klee, Victoria, Walsh, Laurence E., Begemann, Matthias, Elbracht, Miriam, Eggermann, Thomas, Stoppe, Arzu, Stuurman, Kyra, van Slegtenhorst, Marjon, Barakat, Tahsin Stefan, Mulhern, Maureen S., Sands, Tristan T., Cytrynbaum, Cheryl, Weksberg, Rosanna, Isidori, Federica, Pippucci, Tommaso, Severi, Giulia, Montanari, Francesca, Kruer, Michael C., Bakhtiari, Somayeh, Darvish, Hossein, Reutter, Heiko, Hagelueken, Gregor, Geyer, Matthias, Woolf, Adrian S., Posey, Jennifer E., Lupski, James R., Odermatt, Benjamin, and Hilger, Alina C.

Published
2024
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4. Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

Author

Plattner, Christina, Lamberti, Giorgia, Blattmann, Peter, Kirchmair, Alexander, Rieder, Dietmar, Loncova, Zuzana, Sturm, Gregor, Scheidl, Stefan, Ijsselsteijn, Marieke, Fotakis, Georgios, Noureen, Asma, Lisandrelli, Rebecca, Böck, Nina, Nemati, Niloofar, Krogsdam, Anne, Daum, Sophia, Finotello, Francesca, Somarakis, Antonios, Schäfer, Alexander, Wilflingseder, Doris, Gonzalez Acera, Miguel, Öfner, Dietmar, Huber, Lukas A., Clevers, Hans, Becker, Christoph, Farin, Henner F., Greten, Florian R., Aebersold, Ruedi, de Miranda, Noel F.C.C., and Trajanoski, Zlatko

Published
2023
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5. SARS-CoV-2 activates the TLR4/MyD88 pathway in human macrophages: A possible correlation with strong pro-inflammatory responses in severe COVID-19

Author

Sahanic, Sabina, Hilbe, Richard, Dünser, Christina, Tymoszuk, Piotr, Löffler-Ragg, Judith, Rieder, Dietmar, Trajanoski, Zlatko, Krogsdam, Anne, Demetz, Egon, Yurchenko, Maria, Fischer, Christine, Schirmer, Michael, Theurl, Markus, Lener, Daniela, Hirsch, Jakob, Holfeld, Johannes, Gollmann-Tepeköylü, Can, Zinner, Carl P., Tzankov, Alexandar, Zhang, Shen-Ying, Casanova, Jean-Laurent, Posch, Wilfried, Wilflingseder, Doris, Weiss, Guenter, and Tancevski, Ivan

Published
2023
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6. High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

Author

Salcher, Stefan, Sturm, Gregor, Horvath, Lena, Untergasser, Gerold, Kuempers, Christiane, Fotakis, Georgios, Panizzolo, Elisa, Martowicz, Agnieszka, Trebo, Manuel, Pall, Georg, Gamerith, Gabriele, Sykora, Martina, Augustin, Florian, Schmitz, Katja, Finotello, Francesca, Rieder, Dietmar, Perner, Sven, Sopper, Sieghart, Wolf, Dominik, Pircher, Andreas, and Trajanoski, Zlatko

Published
2022
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8. The Recurrent E-Cadherin (CDH1) Mutation c.760G>A Causes Orofacial Clefts but Does Not Predispose to Hereditary Cancer.

Author

Gossner, Lea, Rieder, Dietmar, Müller, Thomas, and Janecke, Andreas R.

Abstract

Objective: Congenital, non-syndromic orofacial clefts (CL/P) are infrequently monogenic in etiology. However, heterozygous pathogenic CDH1 germline variants were reported in a few non-syndromic CL/P families, as well as in one syndromic form of CL/P: the blepharocheilodontic syndrome. CDH1 encodes epithelial cadherin (E-cadherin), and close to 300 different pathogenic CDH1 variants are listed in the ClinVar mutation database. The majority of CDH1 germline variants are implicated in hereditary diffuse gastric cancer (HDGC) susceptibility. The purpose of this study was to classify the CDH1 c.760G>A (p.Asp254Asn) mutation with respect to its resulting phenotype. Methods: Exome sequencing and targeted Sanger sequencing were performed in a family segregating CL/P. A review of pathogenic CDH1 variants in ClinVar and those identified in a PubMed/MEDLINE search was performed. Results: We identified a family with six individuals, who were 35–77 years old (mean 56 years) at their last examination, uniformly affected with bilateral CL/P. The CDH1 c.760G>A variant segregated with CL/P. This variant had been reported in 21 individuals, most often children and young adults, from six families. We determined a significant sex preponderance for this variant regarding CL/P: all 16 male and 5 of 11 female heterozygotes presented with CL/P. Furthermore, none of the heterozygous individuals in seven families reported any gastrointestinal tumors. Conclusions: The recurrent CDH1 c.760G>A mutation confers a high risk for CL/P, with strong male preponderance. This review of 27 mutation carriers, including 3 who were 68, 70, and 77 years of age, indicates that c.760G>A does not confer an increased risk for HDGC. The relevance of differentiating craniofacial from cancer phenotypes in mutation carriers is substantial for precision medicine and for counseling families. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies

Author

Stegmann, Jil D, Kalanithy, Jeshurun C, Dworschak, Gabriel C, Ishorst, Nina, Mingardo, Enrico, Lopes, Filipa M, Ho, Yee Mang, Grote, Phillip, Lindenberg, Tobias T, Yilmaz, Öznur, Channab, Khadija, Seltzsam, Steve, Shril, Shirlee, Hildebrandt, Friedhelm, Boschann, Felix, Heinen, André, Jolly, Angad, Myers, Katherine, McBride, Kim, Bekheirnia, Mir Reza, Bekheirnia, Nasim, Scala, Marcello, Morleo, Manuela, Nigro, Vincenzo, Torella, Annalaura, Pinelli, Michele, Capra, Valeria, Accogli, Andrea, Maitz, Silvia, Spano, Alice, Olson, Rory J, Klee, Eric W, Lanpher, Brendan C, Jang, Se Song, Chae, Jong-Hee, Steinbauer, Philipp, Rieder, Dietmar, Janecke, Andreas R, Vodopiutz, Julia, Vogel, Ida, Blechingberg, Jenny, Cohen, Jennifer L, Riley, Kacie, Klee, Victoria, Walsh, Laurence E, Begemann, Matthias, Elbracht, Miriam, Eggermann, Thomas, Stuurman, Kyra, van Slegtenhorst, Marjon, Stegmann, Jil D, Kalanithy, Jeshurun C, Dworschak, Gabriel C, Ishorst, Nina, Mingardo, Enrico, Lopes, Filipa M, Ho, Yee Mang, Grote, Phillip, Lindenberg, Tobias T, Yilmaz, Öznur, Channab, Khadija, Seltzsam, Steve, Shril, Shirlee, Hildebrandt, Friedhelm, Boschann, Felix, Heinen, André, Jolly, Angad, Myers, Katherine, McBride, Kim, Bekheirnia, Mir Reza, Bekheirnia, Nasim, Scala, Marcello, Morleo, Manuela, Nigro, Vincenzo, Torella, Annalaura, Pinelli, Michele, Capra, Valeria, Accogli, Andrea, Maitz, Silvia, Spano, Alice, Olson, Rory J, Klee, Eric W, Lanpher, Brendan C, Jang, Se Song, Chae, Jong-Hee, Steinbauer, Philipp, Rieder, Dietmar, Janecke, Andreas R, Vodopiutz, Julia, Vogel, Ida, Blechingberg, Jenny, Cohen, Jennifer L, Riley, Kacie, Klee, Victoria, Walsh, Laurence E, Begemann, Matthias, Elbracht, Miriam, Eggermann, Thomas, Stuurman, Kyra, and van Slegtenhorst, Marjon

Abstract

CELSR3 codes for a planar cell polarity protein. We describe twelve affected individuals from eleven independent families with bi-allelic variants in CELSR3. Affected individuals presented with an overlapping phenotypic spectrum comprising central nervous system (CNS) anomalies (7/12), combined CNS anomalies and congenital anomalies of the kidneys and urinary tract (CAKUT) (3/12) and CAKUT only (2/12). Computational simulation of the 3D protein structure suggests the position of the identified variants to be implicated in penetrance and phenotype expression. CELSR3 immunolocalization in human embryonic urinary tract and transient suppression and rescue experiments of Celsr3 in fluorescent zebrafish reporter lines further support an embryonic role of CELSR3 in CNS and urinary tract formation.

Published
2024

10. Kinesin family member 12‐related hepatopathy: A generally indolent disorder with elevated gamma‐glutamyl‐transferase activity.

Author

Vogel, Georg‐Friedrich, Podpeskar, Alexandra, Rieder, Dietmar, Salzer, Helin, Garczarczyk‐Asim, Dorota, Wang, Li, Abuduxikuer, Kuerbanjiang, Wang, Jian‐She, Scharrer, Anke, Faqeih, Eissa Ali, Aseeri, Ali T., Vodopiutz, Julia, Heilos, Andreas, Pichler, Judith, Huber, Wolf‐Dietrich, Müller, Thomas, Knisely, A. S., and Janecke, Andreas R.

Subjects
HEPATIC fibrosis, LIVER failure, CHILD patients, LIVER transplantation, LIVER diseases, GAMMA-glutamyltransferase
Abstract

Exome sequencing (ES) has identified biallelic kinesin family member 12 (KIF12) mutations as underlying neonatal cholestatic liver disease. We collected information on onset and progression of this entity. Among consecutively referred pediatric patients at our centers, diagnostic ES identified 4 patients with novel, biallelic KIF12 variants using the human GRCh38 reference sequence, as KIF12 remains incompletely annotated in the older reference sequence GRCh37. A review of these and of 21 reported patients with KIF12 variants found that presentation with elevated serum transaminase activity in the context of trivial respiratory infection, without clinical features of liver disease, was more common (n = 18) than manifest cholestatic disease progressing rapidly to liver transplantation (LT; n = 7). Onset of liver disease was at age <1 year in 15 patients; LT was more common in this group. Serum gamma‐glutamyl transpeptidase activity (GGT) was elevated in all patients, and total bilirubin was elevated in 15 patients. Liver fibrosis or cirrhosis was present in 14 of 18 patients who were biopsied. The 16 different pathogenic variants and 11 different KIF12 genotypes found were not correlated with age of onset or progression to LT. Identification of biallelic pathogenic KIF12 variants distinguishes KIF12‐related disease from other entities with elevated GGT. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients

Author

García-Mulero, Sandra, primary, Fornelino, Roberto, additional, Punta, Marco, additional, Lise, Stefano, additional, Varela, Mar, additional, del Carpio, Luis P., additional, Moreno, Rafael, additional, Costa-García, Marcel, additional, Rieder, Dietmar, additional, Trajanoski, Zlatko, additional, Gros, Alena, additional, Alemany, Ramón, additional, Piulats, Josep María, additional, and Sanz-Pamplona, Rebeca, additional

Published
2023
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13. Supplementary Figures 1-12 from Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses

Author

Farin, Henner F., primary, Mosa, Mohammed H., primary, Ndreshkjana, Benardina, primary, Grebbin, Britta M., primary, Ritter, Birgit, primary, Menche, Constantin, primary, Kennel, Kilian B., primary, Ziegler, Paul K., primary, Szabó, Lili, primary, Bollrath, Julia, primary, Rieder, Dietmar, primary, Michels, Birgitta E., primary, Kress, Alena, primary, Bozlar, Müge, primary, Darvishi, Tahmineh, primary, Stier, Sara, primary, Kur, Ivan-Maximilano, primary, Bankov, Katrin, primary, Kesselring, Rebecca, primary, Fichtner-Feigl, Stefan, primary, Brüne, Bernhard, primary, Goetze, Thorsten O., primary, Al-Batran, Salah-Eddin, primary, Brandts, Christian H., primary, Bechstein, Wolf O., primary, Wild, Peter J., primary, Weigert, Andreas, primary, Müller, Susanne, primary, Knapp, Stefan, primary, Trajanoski, Zlatko, primary, and Greten, Florian R., primary

Published
2023
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14. Data from Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses

Author

Farin, Henner F., primary, Mosa, Mohammed H., primary, Ndreshkjana, Benardina, primary, Grebbin, Britta M., primary, Ritter, Birgit, primary, Menche, Constantin, primary, Kennel, Kilian B., primary, Ziegler, Paul K., primary, Szabó, Lili, primary, Bollrath, Julia, primary, Rieder, Dietmar, primary, Michels, Birgitta E., primary, Kress, Alena, primary, Bozlar, Müge, primary, Darvishi, Tahmineh, primary, Stier, Sara, primary, Kur, Ivan-Maximilano, primary, Bankov, Katrin, primary, Kesselring, Rebecca, primary, Fichtner-Feigl, Stefan, primary, Brüne, Bernhard, primary, Goetze, Thorsten O., primary, Al-Batran, Salah-Eddin, primary, Brandts, Christian H., primary, Bechstein, Wolf O., primary, Wild, Peter J., primary, Weigert, Andreas, primary, Müller, Susanne, primary, Knapp, Stefan, primary, Trajanoski, Zlatko, primary, and Greten, Florian R., primary

Published
2023
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18. Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses

Author

Farin, Henner F., primary, Mosa, Mohammed H., additional, Ndreshkjana, Benardina, additional, Grebbin, Britta M., additional, Ritter, Birgit, additional, Menche, Constantin, additional, Kennel, Kilian B., additional, Ziegler, Paul K., additional, Szabó, Lili, additional, Bollrath, Julia, additional, Rieder, Dietmar, additional, Michels, Birgitta E., additional, Kress, Alena, additional, Bozlar, Müge, additional, Darvishi, Tahmineh, additional, Stier, Sara, additional, Kur, Ivan-Maximilano, additional, Bankov, Katrin, additional, Kesselring, Rebecca, additional, Fichtner-Feigl, Stefan, additional, Brüne, Bernhard, additional, Goetze, Thorsten O., additional, Al-Batran, Salah-Eddin, additional, Brandts, Christian H., additional, Bechstein, Wolf O., additional, Wild, Peter J., additional, Weigert, Andreas, additional, Müller, Susanne, additional, Knapp, Stefan, additional, Trajanoski, Zlatko, additional, and Greten, Florian R., additional

Published
2023
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22. Correction to: Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

Author

Finotello, Francesca, Mayer, Clemens, Plattner, Christina, Laschober, Gerhard, Rieder, Dietmar, Hackl, Hubert, Krogsdam, Anne, Loncova, Zuzana, Posch, Wilfried, Wilflingseder, Doris, Sopper, Sieghart, Ijsselsteijn, Marieke, Brouwer, Thomas P., Johnson, Douglas, Xu, Yaomin, Wang, Yu, Sanders, Melinda E., Estrada, Monica V., Ericsson-Gonzalez, Paula, Charoentong, Pornpimol, Balko, Justin, da Cunha Carvalho de Miranda, Noel Filipe, and Trajanoski, Zlatko

Published
2019
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23. Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

Author

Finotello, Francesca, Mayer, Clemens, Plattner, Christina, Laschober, Gerhard, Rieder, Dietmar, Hackl, Hubert, Krogsdam, Anne, Loncova, Zuzana, Posch, Wilfried, Wilflingseder, Doris, Sopper, Sieghart, Ijsselsteijn, Marieke, Brouwer, Thomas P., Johnson, Douglas, Xu, Yaomin, Wang, Yu, Sanders, Melinda E., Estrada, Monica V., Ericsson-Gonzalez, Paula, Charoentong, Pornpimol, Balko, Justin, de Miranda, Noel Filipe da Cunha Carvalho, and Trajanoski, Zlatko

Published
2019
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24. Supplementary Figure from Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer

Author

Seeber, Andreas, primary, Battaglin, Francesca, primary, Zimmer, Kai, primary, Kocher, Florian, primary, Baca, Yasmine, primary, Xiu, Joanne, primary, Spizzo, Gilbert, primary, Novotny-Diermayr, Veronica, primary, Rieder, Dietmar, primary, Puccini, Alberto, primary, Swensen, Jeff, primary, Ellis, Michelle, primary, Goldberg, Richard M., primary, Grothey, Axel, primary, Shields, Anthony F., primary, Marshall, John L., primary, Weinberg, Benjamin A., primary, Sackstein, Paul E., primary, Lim, Kiat Hon, primary, Tan, Gek San, primary, Nabhan, Chadi, primary, Korn, W. Michael, primary, Amann, Arno, primary, Trajanoski, Zlatko, primary, Berger, Martin D., primary, Lou, Emil, primary, Wolf, Dominik, primary, and Lenz, Heinz-Josef, primary

Published
2023
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25. Supplementary Table from Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer

Author

Seeber, Andreas, primary, Battaglin, Francesca, primary, Zimmer, Kai, primary, Kocher, Florian, primary, Baca, Yasmine, primary, Xiu, Joanne, primary, Spizzo, Gilbert, primary, Novotny-Diermayr, Veronica, primary, Rieder, Dietmar, primary, Puccini, Alberto, primary, Swensen, Jeff, primary, Ellis, Michelle, primary, Goldberg, Richard M., primary, Grothey, Axel, primary, Shields, Anthony F., primary, Marshall, John L., primary, Weinberg, Benjamin A., primary, Sackstein, Paul E., primary, Lim, Kiat Hon, primary, Tan, Gek San, primary, Nabhan, Chadi, primary, Korn, W. Michael, primary, Amann, Arno, primary, Trajanoski, Zlatko, primary, Berger, Martin D., primary, Lou, Emil, primary, Wolf, Dominik, primary, and Lenz, Heinz-Josef, primary

Published
2023
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26. Supplementary Data from A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer

Author

Trefny, Marcel P., primary, Rothschild, Sacha I., primary, Uhlenbrock, Franziska, primary, Rieder, Dietmar, primary, Kasenda, Benjamin, primary, Stanczak, Michal A., primary, Berner, Fiamma, primary, Kashyap, Abhishek S., primary, Kaiser, Monika, primary, Herzig, Petra, primary, Poechtrager, Severin, primary, Thommen, Daniela S., primary, Geier, Florian, primary, Savic, Spasenija, primary, Jermann, Philip, primary, Alborelli, Ilaria, primary, Schaub, Stefan, primary, Stenner, Frank, primary, Früh, Martin, primary, Trajanoski, Zlatko, primary, Flatz, Lukas, primary, Mertz, Kirsten D., primary, Zippelius, Alfred, primary, and Läubli, Heinz, primary

Published
2023
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28. Functional and Spatial Proteomics Profiling Reveals Intra- and Intercellular Signaling Crosstalk in Colorectal Cancer

Author

Plattner, Christina, primary, Lamberti, Giorgia, additional, Blattmann, Peter, additional, Kirchmair, Alexander, additional, Rieder, Dietmar, additional, Loncova, Zuzana, additional, Sturm, Gregor, additional, Scheidl, Stefan, additional, Ijsselsteijn, Marieke E., additional, Fotakis, Georgios, additional, Noureen, Asma, additional, Lisandrelli, Rebecca, additional, Böck, Nina, additional, Nemati, Niloofar, additional, Krogsdam, Anne, additional, Daum, Sophia, additional, Finotello, Francesca, additional, Samarakis, Antonios, additional, Schäfer, Alexander, additional, Wilfingseder, Doris, additional, Acera, Miguel Gonzalez, additional, Öfner, Dietmar, additional, Huber, Lukas, additional, Clevers, Hans, additional, Becker, Christoph, additional, Farin, Henner, additional, Greten, Florian, additional, Aebersold, Ruedi, additional, de Miranda, Noel F. C. C., additional, and Trajanoski, Zlatko, additional

Published
2023
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29. High-resolution single-cell atlas reveals diversity and plasticity of tumor-associated neutrophils in non-small cell lung cancer

Author

Salcher, Stefan, Sturm, Gregor, Horvath, Lena, Untergasser, Gerold, Kuempers, Christiane, Fotakis, Georgios, Panizzolo, Elisa, Martowicz, Agnieszka, Trebo, Manuel, Pall, Georg, Gamerith, Gabriele, Sykora, Martina, Augustin, Florian, Schmitz, Katja, Finotello, Francesca, Rieder, Dietmar, Perner, Sven, Sopper, Sieghart, Wolf, Dominik, Pircher, Andreas, and Trajanoski, Zlatko

Subjects
Neutrophils, single-cell, NSCLC, data integration
Abstract

This archive contains all data required to reproduce the single-cell data integration and analysis for the paper High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer (https://doi.org/10.1101/2022.05.09.491204 ) In particular, it contains the following files: build_atlas_results.tar.xz contains all intermediate result of the first part of the workflow (data integration and annotation). It is also required to run the second part of the workflow without re-running the data integration steps. containers.tar.xz contains singularity containers that package all software dependencies required to reproduce the analyses core_atlas_scanvi_model.tar.gz contains a scArches model and the corresponding h5ad file (with only highly variable genes). You can use this to project your own data onto the atlas with scArches downstream_anslysis_results.tar.xz contains the results from the second part of the workflow, including an executed HTML version of all jupyter and rmarkdown notebooks that were used to derive the figures from the paper input_data.tar.xz contains the preprocessed input data (e.g. h5ad files for each individual dataset). It is required to run the first part of the analysis workflow. If you want to download the atlas to perform you own analyses, please refer to the CZI Cell-x-gene portal. From there, you can download h5ad (scverse) and rds (Seurat) files with standardized metadata.

Published
2022
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32. Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

Author

Plattner, Christina, primary, Lamberti, Giorgia, additional, Blattmann, Peter, additional, Kirchmair, Alexander, additional, Rieder, Dietmar, additional, Loncova, Zuzana, additional, Sturm, Gregor, additional, Scheidl, Stefan, additional, Ijsselsteijn, Marieke, additional, Fotakis, Georgios, additional, Noureen, Asma, additional, Lisandrelli, Rebecca, additional, Böck, Nina, additional, Nemati, Niloofar, additional, Krogsdam, Anne, additional, Daum, Sophia, additional, Finotello, Francesca, additional, Somarakis, Antonios, additional, Schäfer, Alexander, additional, Wilflingseder, Doris, additional, Acera, Miguel Gonzalez, additional, Öfner, Dietmar, additional, Huber, Lukas A., additional, Clevers, Hans, additional, Becker, Christoph, additional, Farin, Henner F., additional, Greten, Florian R., additional, Abersold, Ruedi, additional, da Cunha Carvalho de Miranda, Noel Filipe, additional, and Trajanoski, Zlatko, additional

Published
2022
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35. High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

Author

Salcher, Stefan, primary, Sturm, Gregor, additional, Horvath, Lena, additional, Untergasser, Gerold, additional, Fotakis, Georgios, additional, Panizzolo, Elisa, additional, Martowicz, Agnieszka, additional, Pall, Georg, additional, Gamerith, Gabriele, additional, Sykora, Martina, additional, Augustin, Florian, additional, Schmitz, Katja, additional, Finotello, Francesca, additional, Rieder, Dietmar, additional, Sopper, Sieghart, additional, Wolf, Dominik, additional, Pircher, Andreas, additional, and Trajanoski, Zlatko, additional

Published
2022
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37. Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer

Author

Seeber, Andreas, primary, Battaglin, Francesca, additional, Zimmer, Kai, additional, Kocher, Florian, additional, Baca, Yasmine, additional, Xiu, Joanne, additional, Spizzo, Gilbert, additional, Novotny-Diermayr, Veronica, additional, Rieder, Dietmar, additional, Puccini, Alberto, additional, Swensen, Jeff, additional, Ellis, Michelle, additional, Goldberg, Richard M., additional, Grothey, Axel, additional, Shields, Anthony F., additional, Marshall, John L., additional, Weinberg, Benjamin A., additional, Sackstein, Paul E., additional, Lim, Kiat Hon, additional, Tan, Gek San, additional, Nabhan, Chadi, additional, Korn, W. Michael, additional, Amann, Arno, additional, Trajanoski, Zlatko, additional, Berger, Martin D., additional, Lou, Emil, additional, Wolf, Dominik, additional, and Lenz, Heinz-Josef, additional

Published
2022
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41. CHD1 controls H3.3 incorporation in adult brain chromatin to maintain metabolic homeostasis and normal lifespan

Author

Schoberleitner, Ines, primary, Bauer, Ingo, additional, Huang, Anming, additional, Andreyeva, Evgeniya N., additional, Sebald, Johanna, additional, Pascher, Katharina, additional, Rieder, Dietmar, additional, Brunner, Melanie, additional, Podhraski, Valerie, additional, Oemer, Gregor, additional, Cázarez-García, Daniel, additional, Rieder, Leila, additional, Keller, Markus A., additional, Winkler, Robert, additional, Fyodorov, Dmitry V., additional, and Lusser, Alexandra, additional

Published
2021
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45. Cardiopulmonary recovery after COVID-19: an observational prospective multicentre trial

Author

Sonnweber, Thomas, primary, Sahanic, Sabina, additional, Pizzini, Alex, additional, Luger, Anna, additional, Schwabl, Christoph, additional, Sonnweber, Bettina, additional, Kurz, Katharina, additional, Koppelstätter, Sabine, additional, Haschka, David, additional, Petzer, Verena, additional, Boehm, Anna, additional, Aichner, Magdalena, additional, Tymoszuk, Piotr, additional, Lener, Daniela, additional, Theurl, Markus, additional, Lorsbach-Köhler, Almut, additional, Tancevski, Amra, additional, Schapfl, Anna, additional, Schaber, Marc, additional, Hilbe, Richard, additional, Nairz, Manfred, additional, Puchner, Bernhard, additional, Hüttenberger, Doris, additional, Tschurtschenthaler, Christoph, additional, Aßhoff, Malte, additional, Peer, Andreas, additional, Hartig, Frank, additional, Bellmann, Romuald, additional, Joannidis, Michael, additional, Gollmann-Tepeköylü, Can, additional, Holfeld, Johannes, additional, Feuchtner, Gudrun, additional, Egger, Alexander, additional, Hoermann, Gregor, additional, Schroll, Andrea, additional, Fritsche, Gernot, additional, Wildner, Sophie, additional, Bellmann-Weiler, Rosa, additional, Kirchmair, Rudolf, additional, Helbok, Raimund, additional, Prosch, Helmut, additional, Rieder, Dietmar, additional, Trajanoski, Zlatko, additional, Kronenberg, Florian, additional, Wöll, Ewald, additional, Weiss, Günter, additional, Widmann, Gerlig, additional, Löffler-Ragg, Judith, additional, and Tancevski, Ivan, additional

Published
2020
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47. Thioguanosine Conversion Enables mRNA‐Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC‐seq DUAL)

Author

Gasser, Catherina, primary, Delazer, Isabel, additional, Neuner, Eva, additional, Pascher, Katharina, additional, Brillet, Karl, additional, Klotz, Sarah, additional, Trixl, Lukas, additional, Himmelstoß, Maximilian, additional, Ennifar, Eric, additional, Rieder, Dietmar, additional, Lusser, Alexandra, additional, and Micura, Ronald, additional

Published
2020
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48. Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy

Author

de Boo, Leonora, primary, Cimino-Mathews, Ashley, additional, Lubeck, Yoni, additional, Daletzakis, Antonios, additional, Opdam, Mark, additional, Sanders, Joyce, additional, Hooijberg, Erik, additional, van Rossum, Annelot, additional, Loncova, Zuzana, additional, Rieder, Dietmar, additional, Trajanoski, Zlatko, additional, Vollebergh, Marieke, additional, Sobral-Leite, Marcelo, additional, van de Vijver, Koen, additional, Broeks, Annegien, additional, van der Wiel, Rianne, additional, van Tinteren, Harm, additional, Linn, Sabine, additional, Horlings, Hugo Mark, additional, and Kok, Marleen, additional

Published
2020
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49. Abstract B60: Perturbation biology of colorectal cancer organoids reveals patient-specific signaling rewiring and interference with immunity

Author

Lamberti, Giorgia, primary, Plattner, Christina, additional, Blattner, Peter, additional, Scheidl, Stefan, additional, Finotello, Francesca, additional, Rieder, Dietmar, additional, Krogsdam, Anne, additional, Farin, Henner, additional, Greten, Florian, additional, Öfner-Velano, Dietmar, additional, de Miranda, Noel, additional, Aebersold, Ruedi, additional, Huber, Lukas, additional, and Trajanoski, Zlatko, additional

Published
2020
Full Text
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