Search

Background Patients with coronavirus disease 2019 (Covid-19) may experience venous thrombosis while data regarding arterial thrombosis are sparse. Methods Prospective multicenter study in 5 hospitals including 373 patients with Covid-19-related pneumonia. Demographic data, laboratory findings including coagulation tests and comorbidities were reported. During the follow-up any arterial or venous thrombotic events and death were registered. Results Among 373 patients, 75 (20%) had a thrombotic event and 75 (20%) died. Thrombotic events included 41 venous thromboembolism and 34 arterial thrombosis. Age, cardiovascular disease, intensive care unit treatment, white blood cells, D-dimer, albumin and troponin blood levels were associated with thrombotic events. In a multivariable regression logistic model, intensive care unit treatment (Odds Ratio [OR]: 6.0; 95% Confidence Interval [CI] 2.8–12.6; p p = 0.022); and albumin levels (OR: 0.49; 95% CI 0.28–0.87; p = 0.014) were associated with ischemic events. Age, sex, chronic obstructive pulmonary disease, diabetes, heart failure, coronary heart disease, intensive care unit treatment, in-hospital thrombotic events, D-dimer, C-reactive protein, troponin, and albumin levels were associated with mortality. A multivariable Cox regression analysis showed that in-hospital thrombotic events (hazard ratio [HR]: 2.72; 95% CI 1.59–4.65; p p = 0.001), and albumin (HR: 0.447; 95% CI 0.277–0.723; p = 0.001) predicted morality. Conclusions Covid-19 patients experience an equipollent rate of venous and arterial thrombotic events, that are associated with poor survival. Early identification and appropriate treatment of Covid-19 patients at risk of thrombosis may improve prognosis.

A history of migratory community, according to a transnational history approach. From Romagna to Connecticut, through the family histories and sources of both the Ellis Island database and the Meldola municipal historical archive, a case-study observatory. With the migratory process of the early twentieth century, the integration and inter-generational relations in the city of Litchfield are investigated throughout the twentieth century.

Background Cardiometabolic disorders may worsen Covid-19 outcomes. We investigated features and Covid-19 outcomes for patients with or without diabetes, and with or without cardiometabolic multimorbidity. Methods We collected and compared data retrospectively from patients hospitalized for Covid-19 with and without diabetes, and with and without cardiometabolic multimorbidity (defined as ≥ two of three risk factors of diabetes, hypertension or dyslipidaemia). Multivariate logistic regression was used to assess the risk of the primary composite outcome (any of mechanical ventilation, admission to an intensive care unit [ICU] or death) in patients with diabetes and in those with cardiometabolic multimorbidity, adjusting for confounders. Results Of 354 patients enrolled, those with diabetes (n = 81), compared with those without diabetes (n = 273), had characteristics associated with the primary composite outcome that included older age, higher prevalence of hypertension and chronic obstructive pulmonary disease (COPD), higher levels of inflammatory markers and a lower PaO2/FIO2 ratio. The risk of the primary composite outcome in the 277 patients who completed the study as of May 15th, 2020, was higher in those with diabetes (Adjusted Odds Ratio (adjOR) 2.04, 95%CI 1.12–3.73, p = 0.020), hypertension (adjOR 2.31, 95%CI: 1.37–3.92, p = 0.002) and COPD (adjOR 2.67, 95%CI 1.23–5.80, p = 0.013). Patients with cardiometabolic multimorbidity were at higher risk compared to patients with no cardiometabolic conditions (adjOR 3.19 95%CI 1.61–6.34, p = 0.001). The risk for patients with a single cardiometabolic risk factor did not differ with that for patients with no cardiometabolic risk factors (adjOR 1.66, 0.90–3.06, adjp = 0.10). Conclusions Patients with diabetes hospitalized for Covid-19 present with high-risk features. They are at increased risk of adverse outcomes, likely because diabetes clusters with other cardiometabolic conditions.

Nascita, storia e rappresentazioni della Repubblica italiana negli studi nei nuovi percorsi della ricerca, con attenzione alla dimensione culturale, di genere e generazionale della memoria pubblica.

Con la proclamazione di Roma capitale, nel mondo democratico-repubblicano maturò il superamento della pregiudiziale astensionistica verso le elezioni e il Parlamento. Fin dal 1877 fu costituito il gruppo di deputati dell’Estrema Sinistra. La scelta partecipazionista determinò l’organizzazione nazionale del Pri (1895) e la difesa del Parlamento come sede della sovranità popolare. I repubblicani italiani continuarono a dividersi sul ruolo del gruppo parlamentare; in una irrisolta dialettica tra integrazione nelle istituzioni monarchiche e vocazione rivoluzionaria

The discussion develops the reflection on recent transnational histories. In that discussion we question about the spaces of “making history”, at global and local level. We discuss on as re-writing a history of the political spaces and how to valorize the territories as fragments of an wider global space. Moving from the “world histories” of France, Italy and Spain, we reflect on other examples of transnational histories, which underline the complexity questions of scale in the transformations of the state and national spaces. The relationship between geography and history, social sciences and “histories” of different age (escaping therefore from the only contemporary history) facilitates a comparative and interdisciplinary approach.

Storia locale e storia regionale comparata, attraverso il "caso" delle Romagne, tra i secoli XIX e XX, con approccio di storia sociale e politica di "spazi" che si incrociano(comunitario e locale, sub-regionale e nazionale, transnazionale persino).

Storia e geografia negli studi di Lucio Gambi: percorsi di ricerca sugli spazi locali (urbani, rurali, inter-regionali) nella storia della sub-regione Romagna

Mito rivoluzionario e rappresentazioni dell'Unione Sovietica nella sinistra italiana e comunista in particolare. La parabola del mito sovietico attraverso i decennali della rivoluzione e il mito della "piccola Russia" nelle culture politiche territoriali (tra Emilia e Toscana)

Simbolismo cromatico e comunicazione politica nell'Italia repubblicana, tra anni Settanta e fine Novecento. La parabola delle tradizioni politiche novecentesche attraverso il linguaggio dei colori.

Si sviluppa un “caso di studio” incentrato su Meldola e sulla sua comunità nel corso del primo secolo post-unitario, tra eventi e rappresentazioni, identità locale e percezioni esterne. Attraverso i momenti salienti della storia statuale e nazionale, riletti attraverso le peculiarità locali e romagnole (in un orizzonte a volte anche sovranazionale ed europeo), lo scopo è quello di evidenziare i fattori di continuità e di mutamento, intrecciando la dimensione politico-istituzionale con quella socio-economica e culturale, i fattori generazionali (le relazioni tra i gruppi di età) e di genere (l’emergere di figure femminili); insomma i nessi molteplici tra processi storici e memorie pubbliche, protagonisti individuali e reti familiar-cetuali, gruppi sociali e nascenti formazioni intese a rappresentarne gli interessi.