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Acoustic droplet ejection (ADE) gently and precisely aliquots nanoliter and picoliter liquid volumes without any physical contact with the solution being transferred. The technology is very automation-friendly, as it is compatible with conventional microplates. Focused energy from an acoustic transducer induces droplet ejection into an inverted standard microplate. The commercial system transfers low-nanoliter volumes of dimethyl sulfoxide–dissolved compound libraries and thereby enables cell-based assays to be performed in 1536-well plates.

Picoliter has a technology for the precise transfer of picoliter and nanoliter volumes of liquid without contact between the device and the fluids being transferred. This is accomplished using focussed acoustic energy that causes droplets to be ejected from a liquid surface. Applications include liquid transfer devices, particle manufacturing, and the production of arrays with probes of any length.