218,019 results on '"Rich, A"'
Search Results
2. Title Page, Copyright
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
3. Contents
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
4. Note from the Editor
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
5. 1. Why Both Feed the Line and Reduce the Line?
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
6. 2. A Refuge in the City
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
7. Introduction: Where Do We Come From? What Are We? Where Are We Going?
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
8. 3. Made for Belonging: Spiritual Practice and the Pleasures of Bridge Building
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
9. 4. Standing Up to the Super Polluters
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
10. 5. Making Your Garden Native and Natural
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
11. 7. Sister Joanna's House of Bread and Peace
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
12. 8. Creating Community
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
13. 6. A Community of Gardeners
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
14. 9. Friends and Neighbors: Photographs from the Open Door Community
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
15. 11. Books to Open Young Minds: For Preschool through Middle School
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
16. 10. Advocating for Children
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
17. 12. The Sweet Spot of Climate Action
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Poyser, Jim, Jordan, Kamela, Carr, Sally, Mans, Yvonne, Brown, Trisha, Kimbrough, Jr., R. Calvin, Rich, Amy, Pope, Jes, Hemminger, William, Stratman, Anna Jean, Hochwender, Cris G., Bredhold, Wendy, Kramer, Kyle, Dewig, Shelley, and Elliott, John A.
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- 2021
18. Deep Learning of the Evolution Operator Enables Forecasting of Out-of-Training Dynamics in Chaotic Systems
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Shokar, Ira J. S., Haynes, Peter H., and Kerswell, Rich R.
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Computer Science - Machine Learning ,Mathematics - Dynamical Systems ,Nonlinear Sciences - Chaotic Dynamics - Abstract
We demonstrate that a deep learning emulator for chaotic systems can forecast phenomena absent from training data. Using the Kuramoto-Sivashinsky and beta-plane turbulence models, we evaluate the emulator through scenarios probing the fundamental phenomena of both systems: forecasting spontaneous relaminarisation, capturing initialisation of arbitrary chaotic states, zero-shot prediction of dynamics with parameter values outside of the training range, and characterisation of dynamical statistics from artificially restricted training datasets. Our results show that deep learning emulators can uncover emergent behaviours and rare events in complex systems by learning underlying mathematical rules, rather than merely mimicking observed patterns.
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- 2025
19. Low-Luminosity Type IIP Supernovae from the Zwicky Transient Facility Census of the Local Universe. I: Luminosity Function, Volumetric Rate
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Das, Kaustav K., Kasliwal, Mansi M., Fremling, Christoffer, Sollerman, Jesper, Perley, Daniel A., De, Kishalay, Tzanidakis, Anastasios, Sit, Tawny, Adams, Scott, Anand, Shreya, Ahumuda, Tomas, Andreoni, Igor, Brennan, Sean, Brink, Thomas, Bruch, Rachel J., Chen, Ping, Chu, Matthew R., Cook, David O., Covarrubias, Sofia, Dahiwale, Aishwarya, Earley, Nicholas, Ho, Anna Y. Q., Gal-Yam, Avishay, Gangopadhyay, Anjasha, Hammerstein, Erica, Hinds, K-Ryan, Karambelkar, Viraj, Kong, Yihan, Kulkarni, S. R., Laz, Theophile Jegou du, Liu, Chang, Meynardie, William, Miller, Adam A., Nir, Guy, Patra, Kishore C., Pessi, Priscila J., Rich, R. Michael, Rehemtulla, Nabeel, Rose, Sam, Rusholme, Ben, Schulze, Steve, Sharma, Yashvi, Singh, Avinash, Smith, Roger, Stein, Robert, Mandigo-Stoba, Milan Sharma, Strotjohann, Nora L., Qin, Yu-Jing, Wise, Jacob, Wold, Avery, Yan, Lin, Yang, Yi, Yao, Yuhan, and Zimmerman, Erez
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the luminosity function and volumetric rate of a sample of Type IIP supernovae (SNe) from the Zwicky Transient Facility Census of the Local Universe survey (CLU). This is the largest sample of Type IIP SNe from a systematic volume-limited survey to-date. The final sample includes 330 Type IIP SNe and 36 low-luminosity Type II (LLIIP) SNe with $M_{\textrm{r,peak}}>-16$ mag, which triples the literature sample of LLIIP SNe. The fraction of LLIIP SNe is $19^{+3}_{-4}\%$ of the total CLU Type IIP SNe population ($8^{+1}_{-2}\%$ of all core-collapse SNe). This implies that while LLIIP SNe likely represent the fate of core-collapse SNe of $8-12$ \Msun\ progenitors, they alone cannot account for the fate of all massive stars in this mass range. To derive an absolute rate, we estimate the ZTF pipeline efficiency as a function of the apparent magnitude and the local surface brightness. We derive a volumetric rate of $(3.9_{-0.4}^{+0.4}) \times 10^{4}\ \textrm{Gpc}^{-3}\ \textrm{yr}^{-1}$ for Type IIP SNe and $(7.3_{-0.6}^{+0.6}) \times 10^{3}\ \textrm{Gpc}^{-3}\ \textrm{yr}^{-1}$ for LLIIP SNe. Now that the rate of LLIIP SNe is robustly derived, the unresolved discrepancy between core-collapse SN rates and star-formation rates cannot be explained by LLIIP SNe alone., Comment: Submitted to PASP
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- 2025
20. Understanding Children's Avatar Making in Social Online Games
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Fu, Yue, Schwamm, Samuel, Baughan, Amanda, Powell, Nicole M, Kronberg, Zoe, Owens, Alicia, Izenman, Emily Renee, Alsabeh, Dania, Hunt, Elizabeth, Rich, Michael, Bickham, David, Radesky, Jenny, and Hiniker, Alexis
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Computer Science - Human-Computer Interaction - Abstract
Social online games like Minecraft and Roblox have become increasingly integral to children's daily lives. Our study explores how children aged 8 to 13 create and customize avatars in these virtual environments. Through semi-structured interviews and gameplay observations with 48 participants, we investigate the motivations behind children's avatar-making. Our findings show that children's avatar creation is motivated by self-representation, experimenting with alter ego identities, fulfilling social needs, and improving in-game performance. In addition, designed monetization strategies play a role in shaping children's avatars. We identify the ''wardrobe effect,'' where children create multiple avatars but typically use only one favorite consistently. We discuss the impact of cultural consumerism and how social games can support children's identity exploration while balancing self-expression and social conformity. This work contributes to understanding how avatar shapes children's identity growth in social online games.
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- 2025
21. The First Chemical Census the Milky Way's Nuclear Star Cluster
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Nandakumar, Govind, Ryde, Nils, Schultheis, Mathias, Rich, R. Michael, Di Matteo, Paola, Thorsbro, Brian, and Mace, Gregory
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
An important step in understanding the formation and evolution of the Nuclear Star Cluster (NSC) is to investigate its chemistry and chemical evolution. Additionally, exploring the relationship of the NSC to the other structures in the Galactic Center and the Milky Way disks is of great interest. Extreme optical extinction has previously prevented optical studies, but near-IR high-resolution spectroscopy is now possible. Here, we present a detailed chemical abundance analysis of 19 elements - more than four times as many as previously published - for 9 stars in the NSC of the Milky Way, observed with the IGRINS spectrometer on the Gemini South telescope. This study provides new, crucial observational evidence to shed light on the origin of the NSC. We demonstrate that it is possible to probe a variety of nucleosynthetic channels, reflecting different chemical evolution timescales. Our findings reveal that the NSC trends for the elements F, Mg, Al, Si, S, K, Ca, Ti, Cr, Mn, Co, Ni, Cu, and Zn, as well as the s-process elements Ba, Ce, Nd, and Yb, generally follow the inner bulge trends within uncertainties. This suggests a likely shared evolutionary history and our results indicate that the NSC population is consistent with the chemical sequence observed in the inner Galaxy (the inner-disk sequence). However, we identify a significant and unexplained difference in the form of higher Na abundances in the NSC compared to the inner-bulge. This is also observed in few Galactic globular clusters, and may suggest a common enrichment process at work in all these systems., Comment: 10 pages, 4 figures, Accepted for publication in The Astrophysical Journal Letters
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- 2025
22. A Massive Black Hole 0.8 kpc from the Host Nucleus Revealed by the Offset Tidal Disruption Event AT2024tvd
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Yao, Yuhan, Chornock, Ryan, Ward, Charlotte, Hammerstein, Erica, Sfaradi, Itai, Margutti, Raffaella, Kelley, Luke Zoltan, Lu, Wenbin, Liu, Chang, Wise, Jacob, Sollerman, Jesper, Alexander, Kate D., Bellm, Eric C., Drake, Andrew J., Fremling, Christoffer, Gilfanov, Marat, Graham, Matthew J., Groom, Steven L., Hinds, K. R., Kulkarni, S. R., Miller, Adam A., Miller-Jones, James C. A., Nicholl, Matt, Perley, Daniel A., Purdum, Josiah, Ravi, Vikram, Rich, R. Michael, Rehemtulla, Nabeel, Riddle, Reed, Smith, Roger, Stein, Robert, Sunyaev, Rashid, van Velzen, Sjoert, and Wold, Avery
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Tidal disruption events (TDEs) that are spatially offset from the nucleus of their host galaxies offer a new probe of massive black hole (MBH) wanderers, binaries, triples, and recoiling MBHs. Here we present AT2024tvd, the first off-nuclear TDE identified through optical sky surveys. High-resolution imaging with the Hubble Space Telescope shows that AT2024tvd is $0.914\pm 0.010$ arcsec offset from the apparent center of its host galaxy, corresponding to a projected distance of $0.808\pm 0.009$ kpc at $z=0.045$. AT2024tvd exhibits typical properties of nuclear TDEs, including a persistent hot UV/optical component that peaks at $L_{ bb}\sim 6\times 10^{43}\,erg\,s^{-1}$, broad hydrogen lines in its optical spectra, and delayed brightening of luminous ($L_{ X,peak}\sim 3\times 10^{43}\,erg\,s^{-1}$), highly variable soft X-ray emission. The MBH mass of AT2024tvd is $10^{6\pm1}\,M_\odot$, at least 10 times lower than its host galaxy's central black hole mass ($\gtrsim 10^8\,M_\odot$). The MBH in AT2024tvd has two possible origins: a wandering MBH from the lower-mass galaxy in a minor merger during the dynamical friction phase or a recoiling MBH ejected by triple interactions. Combining AT2024tvd with two previously known off-nuclear TDEs discovered in X-rays (3XMM\,J2150 and EP240222a), which likely involve intermediate-mass black holes in satellite galaxies, we find that the parent galaxies of all three events are very massive ($\sim 10^{10.9}\,M_\odot$). This result aligns with expectations from cosmological simulations that the number of offset MBHs scales linearly with the host halo mass., Comment: 26 pages, 16 figures, 4 tables. Submitted to journal on 24 Feb 2025. Comments welcome
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- 2025
23. External Large Foundation Model: How to Efficiently Serve Trillions of Parameters for Online Ads Recommendation
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Liang, Mingfu, Liu, Xi, Jin, Rong, Liu, Boyang, Suo, Qiuling, Zhou, Qinghai, Zhou, Song, Chen, Laming, Zheng, Hua, Li, Zhiyuan, Jiang, Shali, Yang, Jiyan, Xia, Xiaozhen, Yang, Fan, Badr, Yasmine, Wen, Ellie, Xu, Shuyu, Chen, Hansey, Zhang, Zhengyu, Nie, Jade, Yang, Chunzhi, Zeng, Zhichen, Zhang, Weilin, Huang, Xingliang, Li, Qianru, Wang, Shiquan, Lyu, Evelyn, Lu, Wenjing, Zhang, Rui, Wang, Wenjun, Rudy, Jason, Hang, Mengyue, Wang, Kai, Ma, Yinbin, Wang, Shuaiwen, Zeng, Sihan, Tang, Tongyi, Wei, Xiaohan, Jin, Longhao, Zhang, Jamey, Chen, Marcus, Zhang, Jiayi, Huang, Angie, Zhang, Chi, Zhao, Zhengli, Yang, Jared, Jin, Qiang, Chen, Xian, Amlesahwaram, Amit Anand, Song, Lexi, Luo, Liang, Hao, Yuchen, Xiao, Nan, Yetim, Yavuz, Pan, Luoshang, Liu, Gaoxiang, Hu, Yuxi, Huang, Yuzhen, Xu, Jackie, Zhu, Rich, Zhang, Xin, Liu, Yiqun, Yin, Hang, Chen, Yuxin, Zhang, Buyun, Liu, Xiaoyi, Wang, Xingyuan, Mao, Wenguang, Li, Zhijing, Huang, Qin, Sun, Chonglin, Mao, Shupin, Au, Benjamin, Qin, Jingzheng, Yao, Peggy, Choi, Jae-Woo, Gao, Bin, Wang, Ernest, Zhang, Lei, Chen, Wen-Yen, Lee, Ted, Zha, Jay, Meng, Yi, Gong, Alex, Gao, Edison, Vahdatpour, Alireza, Han, Yiping, Yao, Yantao, Kureha, Toshinari, Chang, Shuo, Sultan, Musharaf, Bocharov, John, Chordia, Sagar, Gan, Xiaorui, Sun, Peng, Liu, Rocky, Long, Bo, Chen, Wenlin, Kolay, Santanu, and Li, Huayu
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Computer Science - Information Retrieval ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
Ads recommendation is a prominent service of online advertising systems and has been actively studied. Recent studies indicate that scaling-up and advanced design of the recommendation model can bring significant performance improvement. However, with a larger model scale, such prior studies have a significantly increasing gap from industry as they often neglect two fundamental challenges in industrial-scale applications. First, training and inference budgets are restricted for the model to be served, exceeding which may incur latency and impair user experience. Second, large-volume data arrive in a streaming mode with data distributions dynamically shifting, as new users/ads join and existing users/ads leave the system. We propose the External Large Foundation Model (ExFM) framework to address the overlooked challenges. Specifically, we develop external distillation and a data augmentation system (DAS) to control the computational cost of training/inference while maintaining high performance. We design the teacher in a way like a foundation model (FM) that can serve multiple students as vertical models (VMs) to amortize its building cost. We propose Auxiliary Head and Student Adapter to mitigate the data distribution gap between FM and VMs caused by the streaming data issue. Comprehensive experiments on internal industrial-scale applications and public datasets demonstrate significant performance gain by ExFM., Comment: Accepted by the ACM Web Conference (WWW) 2025 Industrial Track as Oral Presentation
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- 2025
24. Data Sharing in the PRIMED Consortium: Design, implementation, and recommendations for future policymaking
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Smith, Johanna L., Wong, Quenna, Hornsby, Whitney, Conomos, Matthew P., Heavner, Benjamin D., Kullo, Iftikhar J., Psaty, Bruce M., Rich, Stephen S., Tayo, Bamidele, Natarajan, Pradeep, Nelson, Sarah C., Group, Polygenic Risk Methods in Diverse Populations PRIMED Consortium Data Sharing Working, and Consortium, Polygenic Risk Methods in Diverse Populations PRIMED
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Quantitative Biology - Other Quantitative Biology - Abstract
Sharing diverse genomic and other biomedical datasets is critical to advance scientific discoveries and their equitable translation to improve human health. However, data sharing remains challenging in the context of legacy datasets, evolving policies, multi-institutional consortium science, and international stakeholders. The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium was established to improve the performance of polygenic risk estimates for a broad range of health and disease outcomes with global impacts. Improving polygenic risk score performance across genetically diverse populations requires access to large, diverse cohorts. We report on the design and implementation of data sharing policies and procedures developed in PRIMED to aggregate and analyze data from multiple, heterogeneous sources while adhering to existing data sharing policies for each integrated dataset. We describe two primary data sharing mechanisms: coordinated dbGaP applications and a Consortium Data Sharing Agreement, as well as provide alternatives when individual-level data cannot be shared within the Consortium (e.g., federated analyses). We also describe technical implementation of Consortium data sharing in the NHGRI Analysis Visualization and Informatics Lab-space (AnVIL) cloud platform, to share derived individual-level data, genomic summary results, and methods workflows with appropriate permissions. As a Consortium making secondary use of pre-existing data sources, we also discuss challenges and propose solutions for release of individual- and summary-level data products to the broader scientific community. We make recommendations for ongoing and future policymaking with the goal of informing future consortia and other research activities.
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- 2025
25. A Luminous Red Optical Flare and Hard X-ray Emission in the Tidal Disruption Event AT2024kmq
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Ho, Anna Y. Q., Yao, Yuhan, Matsumoto, Tatsuya, Schroeder, Genevieve, Coughlin, Eric, Perley, Daniel A., Andreoni, Igor, Bellm, Eric C., Chen, Tracy X., Chornock, Ryan, Covarrubias, Sofia, Das, Kaustav, Fremling, Christoffer, Gilfanov, Marat, Hinds, K. R., Jarvis, Dan, Kasliwal, Mansi M., Liu, Chang, Lyman, Joseph D., Masci, Frank J., Prince, Thomas A., Ravi, Vikram, Rich, R. Michael, Riddle, Reed, Sevilla, Jason, Smith, Roger, Sollerman, Jesper, Somalwar, Jean J., Srinivasaragavan, Gokul P., Sunyaev, Rashid, Vail, Jada L., Wise, Jacob L., and Yun, Sol Bin
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present the optical discovery and multiwavelength follow-up observations of AT2024kmq, a likely tidal disruption event (TDE) associated with a supermassive ($M_{\rm BH}\sim 10^{8} M_\odot$) black hole in a massive galaxy at $z=0.192$. The optical light curve of AT2024kmq exhibits two distinct peaks: an early fast (timescale 1 d) and luminous ($M\approx-20$ mag) red peak, then a slower (timescale 1 month) blue peak with a higher optical luminosity ($M\approx-22$ mag) and featureless optical spectra. The second component is similar to the spectroscopic class of "featureless TDEs" in the literature, and during this second component we detect highly variable, luminous ($L_X\approx 10^{44}$ erg s$^{-1}$), and hard ($f_\nu \propto \nu^{-1.5}$) X-ray emission. Luminous ($10^{29} $erg s$^{-1}$ Hz$^{-1}$ at 10 GHz) but unchanging radio emission likely arises from an underlying active galactic nucleus. The luminosity, timescale, and color of the early red optical peak can be explained by synchrotron emission, or alternatively by thermal emission from material at a large radius ($R\approx\mathrm{few}\times10^{15}$ cm). Possible physical origins for this early red component include an off-axis relativistic jet, and shocks from self-intersecting debris leading to the formation of the accretion disk. Late-time radio observations will help distinguish between the two possibilities., Comment: 23 pages, 7 figures, 6 tables. Submitted to journal on 11 Feb 2025. Comments welcome
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- 2025
26. The Hubble Space Telescope Survey of M31 Satellite Galaxies IV. Survey Overview and Lifetime Star Formation Histories
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Savino, A., Weisz, D. R., Dolphin, A. E., Durbin, M. J., Kallivayalil, N., Wetzel, A., Anderson, J., Besla, G., Boylan-Kolchin, M., Brown, T. M., Bullock, J. S., Cole, A. A., Collins, M. L. M., Cooper, M. C., Deason, A. J., Dotter, A. L., Fardal, M., Ferguson, A. M. N., Fritz, T. K., Geha, M. C., Gilbert, K. M., Guhathakurta, P., Ibata, R., Irwin, M. J., Jeon, M., Kirby, E. N., Lewis, G. F., Mackey, D., Majewski, S. R., Martin, N., McConnachie, A., Patel, E., Rich, R. M., Skillman, E. D., Simon, J. D., Sohn, S. T., Tollerud, E. J., and van der Marel, R. P.
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Astrophysics - Astrophysics of Galaxies - Abstract
From $>1000$ orbits of HST imaging, we present deep homogeneous resolved star color-magnitude diagrams that reach the oldest main sequence turnoff and uniformly measured star formation histories (SFHs) of 36 dwarf galaxies ($-6 \ge M_V \ge -17$) associated with the M31 halo, and for 10 additional fields in M31, M33, and the Giant Stellar Stream. From our SFHs we find: i) the median stellar age and quenching epoch of M31 satellites correlate with galaxy luminosity and galactocentric distance. Satellite luminosity and present-day distance from M31 predict the satellite quenching epoch to within $1.8$ Gyr at all epochs. This tight relationship highlights the fundamental connection between satellite halo mass, environmental history, and star formation duration. ii) There is no difference between the median SFH of galaxies on and off the great plane of Andromeda satellites. iii) $\sim50$\% of our M31 satellites show prominent ancient star formation ($>12$ Gyr ago) followed by delayed quenching ($8-10$ Gyr ago), which is not commonly observed among the MW satellites. iv) A comparison with TNG50 and FIRE-2 simulated satellite dwarfs around M31-like hosts show that some of these trends (dependence of SFH on satellite luminosity) are reproduced in the simulations while others (dependence of SFH on galactocentric distance, presence of the delayed-quenching population) are weaker or absent. We provide all photometric catalogs and SFHs as High-Level Science Products on MAST., Comment: Accepted for publication on ApJ. 47 pages, 24 figures, 12 tables. Corresponding HLSP data can be retrieved at: https://archive.stsci.edu/hlsp/m31-satellites
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- 2025
27. The Galactic Bulge exploration IV.: RR~Lyrae stars as traces of the Galactic bar -- 3D and 5D analysis, extinction variation
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Prudil, Z., Kunder, A., Silva, L. Beraldo e, Gough-Kelly, S., Rejkuba, M., Anderson, S. R., Debattista, V. P., Gerhard, O., Rich, R. M., Nataf, D. M., Koch-Hansen, A. J., Savino, A., and Dékány, I.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We created new reddening maps and derived new extinction laws from visual to near-infrared passbands using improved RR~Lyrae period-absolute magnitude-metallicity relations, thus enabling distance estimates for individual bulge RR~Lyrae variables. The extinction law is most uniform in RIK and RJK and the distances to individual RR~Lyrae based on these colors are determined with an accuracy six and four percent, respectively. Using only the near-infrared passbands for distance estimation we inferred the distance to the Galactic center equal to djk = 8.2 +- 0.001(stat) +- 0.53(sys)pc after geometrical correction. We show that variations in the extinction law toward the Galactic bulge can mimic a barred spatial distribution in the bulge RR~Lyrae star population in visual passbands. This arises from a gradient in extinction differences along Galactic longitudes and latitudes, which can create the perception of the Galactic bar, particularly when using visual passband-based distances. A barred angle in the RR~Lyrae spatial distribution disappears when near-infrared passband-based distances are used, as well as when reddening law variations are incorporated in visual passband-based distances. The prominence of the bar, as traced by RR~Lyrae stars, depends on their metallicity, with metal-poor RR~Lyrae stars ([Fe/H]<-1.0dex) showing little to no tilt with respect to the bar. Metal-rich ([Fe/H]>-1.0dex) RR~Lyrae stars do show a barred/bulge signature in spatial properties derived using near-infrared distances, with an angle {\iota} = 18 +- 5deg, consistent with previous bar measurements from the literature. The 5D kinematic analysis, primarily based on transverse velocities, indicates a rotational lag in RR~Lyrae stars compared to red clump giants. Despite variations in the extinction law, our kinematic conclusions are robust across different distance estimation methods., Comment: Accepted for publication in A&A
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- 2025
28. Clumps as multiscale structures in cosmic noon galaxies
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Kalita, Boris S, Suzuki, Tomoko L, Kashino, Daichi, Silverman, John D, Daddi, Emanuele, Ho, Luis C, Ding, Xuheng, Mercier, Wilfried, Faisst, Andreas L, Sheth, Kartik, Valentino, Francesco, Puglisi, Annagrazia, Saito, Toshiki, Kakkad, Darshan, Ilbert, Olivier, Khostovan, Ali Ahmad, Liu, Zhaoxuan, Tanaka, Takumi, Magdis, Georgios, Zavala, Jorge A, Tan, Qinghua, Kartaltepe, Jeyhan S, Yang, Lilan, Koekemoer, Anton M, McKinney, Jed, Robertson, Brant E, Jin, Shuowen, Hayward, Christopher C, Hirschmann, Michaela, Franco, Maximilien, Shuntov, Marko, Gozaliasl, Ghassem, Kaminsky, Aidan, and Rich, R Michael
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Astrophysics - Astrophysics of Galaxies - Abstract
Star-forming clumps have been found to significantly influence the star formation of gas-rich $z>1$ galaxies. Using public data from JWST/NIRCam (COSMOS-Web) and ALMA (FMOS-COSMOS), we study a sample of 32 massive ($>10^{10.5}\,\rm M_{\odot}$) main-sequence galaxies at $z_{\rm spec}\sim1.5$ with $\sim0.3\,\rm kpc$ resolution. We create composite morphological models consisting of bulge, disk, and clumps to fully 'deconstruct' the galaxy images. With the resulting measurements of the flux and size of these components, we find the following: (I)The combined contribution of clumps is $1-30\%$ towards the net star formation rate (SFR) of the host while contributing $1-20\%$ to its stellar mass. The clumps show a correlation between their stellar mass and SFR, but have an increased specific-SFR (sSFR) relative to the star-forming main sequence, with offsets ranging from $0\lesssim\Delta\log\rm sSFR\lesssim 0.4$. They feature star formation surface densities of $10^{-2}-10^{2}\,\rm M_{\odot}/yr/kpc^{2}$, consistent with values observed in local star-forming and starburst galaxies. (II)The clumps span a large range of characteristic sizes ($r_{e}\sim0.1-1\,\rm kpc$) and stellar masses ($\sim 10^{8.0-9.5}\,\rm M_{\odot}$). We estimate a mass-size relation ($r_{e}\propto\rm M_{\star}^{\,0.52\pm0.07}$) along with a stellar mass function (slope, $\alpha=-1.85\pm 0.19$), both suggesting a hierarchical nature similar to that expected in star-forming regions in local galaxies. (III)Our measurements agree with the properties of stellar clumps in $z\gtrsim1$ lensed systems, bridging the gap between lensed and unlensed studies by detecting structures at sub-kpc scales.(IV)Clumps are found to be preferentially located along spiral features visible primarily in the residual rest-frame near-IR images. In conclusion, we present an observation-based, coherent picture of star-forming clumps at $z>1$., Comment: Published in MNRAS; 22 pages, 24 figures
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- 2025
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29. Proteomics of left ventricular structure in the Multi‐Ethnic Study of Atherosclerosis
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Peterson, Tess E, Lima, Joao AC, Shah, Sanjiv J, Bluemke, David A, Bertoni, Alain G, Liu, Yongmei, Ngo, Debby, Varadarajan, Vinithra, Mychaleckyj, Josyf C, Johnson, Craig W, Psaty, Bruce M, Clish, Clary B, Taylor, Kent D, Durda, Peter, Tracy, Russell P, Gerszten, Robert E, Rich, Stephen S, Rotter, Jerome I, Post, Wendy S, and Pankow, James S
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Biomedical and Clinical Sciences ,Cardiovascular Medicine and Haematology ,Aging ,Heart Disease ,Atherosclerosis ,Cardiovascular ,Clinical Research ,Biotechnology ,2.1 Biological and endogenous factors ,Humans ,Female ,Male ,Proteomics ,Middle Aged ,Heart Ventricles ,Magnetic Resonance Imaging ,Cine ,Ventricular Remodeling ,Biomarkers ,Aged ,United States ,Cross-Sectional Studies ,Ethnicity ,Ventricular Function ,Left ,Cardiovascular magnetic resonance imaging ,Left ventricular remodelling ,Cardiorespiratory Medicine and Haematology ,Cardiovascular medicine and haematology - Abstract
AimsProteomic profiling offers an expansive approach to biomarker discovery and mechanistic hypothesis generation for LV remodelling, a critical component of heart failure (HF). We sought to identify plasma proteins cross-sectionally associated with left ventricular (LV) size and geometry in a diverse population-based cohort without known cardiovascular disease (CVD).Methods and resultsAmong participants of the Multi-Ethnic Study of Atherosclerosis (MESA), we quantified plasma abundances of 1305 proteins using an aptamer-based platform at exam 1 (2000-2002) and exam 5 (2010-2011) and assessed LV structure by cardiac magnetic resonance (CMR) at the same time points. We used multivariable linear regression with robust variance to assess cross-sectional associations between plasma protein abundances and LV structural characteristics at exam 1, reproduced findings in later-life at exam 5, and explored relationships of associated proteins using annotated enrichment analysis. We studied 763 participants (mean age 60 ± 10 years at exam 1; 53% female; 19% Black race; 31% Hispanic ethnicity). Following adjustment for renal function and traditional CVD risk factors, plasma levels of 3 proteins were associated with LV mass index at both time points with the same directionality (FDR
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- 2025
30. Oral Regimens for Rifampin-Resistant, Fluoroquinolone-Susceptible Tuberculosis.
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Guglielmetti, Lorenzo, Khan, Uzma, Velásquez, Gustavo, Gouillou, Maelenn, Abubakirov, Amanzhan, Baudin, Elisabeth, Berikova, Elmira, Berry, Catherine, Bonnet, Maryline, Cellamare, Matteo, Chavan, Vijay, Cox, Vivian, Dakenova, Zhanna, de Jong, Bouke, Ferlazzo, Gabriella, Karabayev, Aydarkhan, Kirakosyan, Ohanna, Kiria, Nana, Kunda, Mikanda, Lachenal, Nathalie, Lecca, Leonid, McIlleron, Helen, Motta, Ilaria, Toscano, Sergio, Mushtaque, Hebah, Nahid, Payam, Oyewusi, Lawrence, Panda, Samiran, Patil, Sandip, Phillips, Patrick, Ruiz, Jimena, Salahuddin, Naseem, Garavito, Epifanio, Seung, Kwonjune, Ticona, Eduardo, Trippa, Lorenzo, Vasquez, Dante, Wasserman, Sean, Rich, Michael, Varaine, Francis, and Mitnick, Carole
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Humans ,Rifampin ,Adult ,Fluoroquinolones ,Female ,Antitubercular Agents ,Male ,Administration ,Oral ,Drug Therapy ,Combination ,Tuberculosis ,Multidrug-Resistant ,Middle Aged ,Mycobacterium tuberculosis ,Nitroimidazoles ,Young Adult ,Diarylquinolines ,Intention to Treat Analysis ,Oxazoles - Abstract
BACKGROUND: For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs to treat tuberculosis and enhanced funding now permit randomized, controlled trials of shortened-duration, all-oral treatments for rifampin-resistant tuberculosis. METHODS: We conducted a phase 3, multinational, open-label, randomized, controlled noninferiority trial to compare standard therapy for treatment of fluoroquinolone-susceptible, rifampin-resistant tuberculosis with five 9-month oral regimens that included various combinations of bedaquiline (B), delamanid (D), linezolid (L), levofloxacin (Lfx) or moxifloxacin (M), clofazimine (C), and pyrazinamide (Z). Participants were randomly assigned (with the use of Bayesian response-adaptive randomization) to receive one of five combinations or standard therapy. The primary end point was a favorable outcome at week 73, defined by two negative sputum culture results or favorable bacteriologic, clinical, and radiologic evolution. The noninferiority margin was -12 percentage points. RESULTS: Among the 754 participants who underwent randomization, 699 were included in the modified intention-to-treat analysis, and 562 in the per-protocol analysis. In the modified intention-to-treat analysis, 80.7% of the patients in the standard-therapy group had favorable outcomes. The risk difference between standard therapy and each of the four new regimens that were found to be noninferior in the modified intention-to-treat population was as follows: BCLLfxZ, 9.8 percentage points (95% confidence interval [CI], 0.9 to 18.7); BLMZ, 8.3 percentage points (95% CI, -0.8 to 17.4); BDLLfxZ, 4.6 percentage points (95% CI, -4.9 to 14.1); and DCMZ, 2.5 percentage points (95% CI, -7.5 to 12.5). Differences were similar in the per-protocol population, with the exception of DCMZ, which was not noninferior in that population. The proportion of participants with grade 3 or higher adverse events was similar across the regimens. Grade 3 or higher hepatotoxic events occurred in 11.7% of participants overall and in 7.1% of those receiving standard therapy. CONCLUSIONS: Consistent results across all the analyses support the noninferior efficacy of three all-oral shortened regimens for the treatment of rifampin-resistant tuberculosis. (Funded by Unitaid and others; endTB ClinicalTrials.gov number, NCT02754765.).
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- 2025
31. Gastric Outlet Obstruction as a Result of an Inguinal Hernia
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Wohlford, Luke and Bounds, Rich
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Gastric outlet obstruction ,Inguinal Hernia - Abstract
Case Presentation: We present a case of a 79-year-old male with gastric outlet obstruction resulting from a stomach herniation through a large left inguinal hernia.Discussion: Stomach-containing inguinal hernias are a rare cause of gastric outlet obstruction. Treatment options range from conservative to surgical management. Once identified with imaging, prompt treatment should be initiated to prevent incarceration, strangulation, and gastric necrosis.
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- 2025
32. Surface remodeling and inversion of cell-matrix interactions underlie community recognition and dispersal in Vibrio cholerae biofilms.
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Moreau, Alexis, Nguyen, Danh, Hinbest, Alexander, Zamora, Anthony, Weerasekera, Ranjuna, Matej, Katherine, Zhou, Xuening, Sanchez, Sandra, Rodriguez Brenes, Ignacio, Tai, Jung-Shen, Nadell, Carey, Ng, Wai-Leung, Gordon, Vernita, Komarova, Natalia, Olson, Rich, Li, Ying, and Yan, Jing
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Biofilms ,Vibrio cholerae ,Bacterial Proteins ,Polysaccharides ,Bacterial ,Extracellular Matrix ,Bacterial Adhesion ,Polysaccharide-Lyases - Abstract
Biofilms are ubiquitous surface-associated bacterial communities embedded in an extracellular matrix. It is commonly assumed that biofilm cells are glued together by the matrix; however, how the specific biochemistry of matrix components affects the cell-matrix interactions and how these interactions vary during biofilm growth remain unclear. Here, we investigate cell-matrix interactions in Vibrio cholerae, the causative agent of cholera. We combine genetics, microscopy, simulations, and biochemical analyses to show that V. cholerae cells are not attracted to the main matrix component (Vibrio polysaccharide, VPS), but can be attached to each other and to the VPS network through surface-associated VPS and crosslinks formed by the protein Bap1. Downregulation of VPS production and surface trimming by the polysaccharide lyase RbmB cause surface remodeling as biofilms age, shifting the nature of cell-matrix interactions from attractive to repulsive and facilitating cell dispersal as aggregated groups. Our results shed light on the dynamics of diverse cell-matrix interactions as drivers of biofilm development.
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- 2025
33. Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes.
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Mei, Janet, Salim, Hamza, Lakhani, Dhairya, Luna, Licia, Balar, Aneri, Shahriari, Mona, Hyson, Nathan, Deng, Francis, Dmytriw, Adam, Guenego, Adrien, Vagal, Vaibhav, Urrutia, Victor, Marsh, Elisabeth, Lu, Hanzhang, Xu, Risheng, Leigh, Rich, Wolman, Dylan, Shah, Gaurang, Pulli, Benjamin, Nael, Kambiz, Albers, Gregory, Wintermark, Max, Heit, Jeremy, Faizy, Tobias, Hillis, Argye, Llinas, Raf, and Yedavalli, Vivek
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Humans ,Male ,Female ,Aged ,Middle Aged ,Ischemic Stroke ,Retrospective Studies ,Aged ,80 and over ,Reperfusion ,Recovery of Function ,Thrombolytic Therapy ,Cerebrovascular Circulation ,Cerebral Veins - Abstract
OBJECTIVE: Venous outflow (VO) impairment predicts unfavorable outcomes in patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO). Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated with unfavorable 90-day functional outcomes despite successful reperfusion. This study investigates the association between PVT and percent change on the National Institutes of Health Stroke Scale (NIHSS) among AIS-LVO patients who have undergone successful reperfusion. METHODS: We performed a retrospective analysis of prospectively collected data from consecutive adult AIS-LVO patients with successful reperfusion (modified Thrombolysis in Cerebral Infarction 2b/2c/3). PVT+ was defined as Tmax ≥10 s in the superior sagittal sinus, torcula, or both. The primary outcome was continuous NIHSS percent change and dichotomous NIHSS percent change ≥70%. Regression analyses were performed to assess the effect of PVT on NIHSS percent change. RESULTS: In 119 patients of median (IQR) age 71 (63-81) years, the admission and discharge NIHSS scores were significantly higher in PVT+ patients compared to PVT- patients (17 [14-23.5] vs. 13 [9.5-19], p = 0.011, and 7.5 [4-12] vs. 3 [1-7], p 6 s volume, and hemorrhagic transformation, PVT+ was significantly associated with lower NIHSS percent change (B = -0.163, 95%CI -0.326 to -0.001, p = 0.049) and was less likely to achieve higher than 70% NIHSS improvement (OR = 0.331, 95% CI 0.127-0.863, p = 0.024). INTERPRETATION: PVT+ was significantly associated with reduced neurological improvement despite successful reperfusion in AIS-LVO patients, highlighting the critical role of VO impairment in short-term functional outcomes. These findings further validate PVT as a valuable adjunct imaging biomarker derived from CTP for assessing VO profiles in AIS-LVO.
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- 2025
34. Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure
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Peterson, Tess E, Hahn, Virginia S, Moaddel, Ruin, Zhu, Min, Haberlen, Sabina A, Palella, Frank J, Plankey, Michael, Bader, Joel S, Lima, Joao AC, Gerszten, Robert E, Rotter, Jerome I, Rich, Stephen S, Heckbert, Susan R, Kirk, Gregory D, Piggott, Damani A, Ferrucci, Luigi, Margolick, Joseph B, Brown, Todd T, Wu, Katherine C, and Post, Wendy S
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Biomedical and Clinical Sciences ,Immunology ,Clinical Research ,Aging ,Heart Disease ,Biotechnology ,HIV/AIDS ,Infectious Diseases ,Cardiovascular ,Sexually Transmitted Infections ,Infection ,Good Health and Well Being ,Humans ,Heart Failure ,HIV Infections ,Proteomics ,Female ,Male ,Middle Aged ,Atrial Remodeling ,Adult ,Magnetic Resonance Imaging ,Heart Atria ,Proteome - Abstract
People living with HIV are at higher risk of heart failure and associated left atrial remodeling compared to people without HIV. Mechanisms are unclear but have been linked to inflammation and premature aging. Here we obtain plasma proteomics concurrently with cardiac magnetic resonance imaging in two independent study populations to identify parallels between HIV-related and aging-related immune dysfunction that could contribute to atrial remodeling and clinical heart failure. We discover a plasma proteomic signature that may in part reflect or contribute to HIV-associated atrial remodeling, many features of which are associated with older age and time to incident heart failure among an independent community-based cohort without HIV. This proteomic profile was statistically enriched for immune checkpoint proteins, tumor necrosis factor signaling, ephrin signaling, and extracellular matrix organization, identifying possible shared pathways in HIV and aging that may contribute to risk of heart failure.
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- 2025
35. A faunal inventory of methane seeps on the Pacific margin of Costa Rica
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Seid, Charlotte A, Hiley, Avery S, McCowin, Marina F, Carvajal, José I, Cha, Harim, Ahyong, Shane T, Ashford, Oliver S, Breedy, Odalisca, Eernisse, Douglas J, Goffredi, Shana K, Hendrickx, Michel E, Kocot, Kevin M, Mah, Christopher L, Miller, Allison K, Koch, Nicolás Mongiardino, Mooi, Rich, O'Hara, Timothy D, Pleijel, Fredrik, Stiller, Josefin, Tilic, Ekin, Valentich-Scott, Paul, Warén, Anders, Wicksten, Mary K, Wilson, Nerida G, Cordes, Erik E, Levin, Lisa A, Cortés, Jorge, and Rouse, Greg W
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Biological Sciences ,Evolutionary Biology ,Biodiversity ,biogeography ,Central America ,chemosynthetic ecosystem ,COI ,deep sea ,DNA'barcodes' ,molecular taxonomy ,review ,DNA ‘barcodes’ ,Zoology ,Ecology ,Evolutionary biology - Abstract
The methane seeps on the Pacific margin of Costa Rica support extensive animal diversity and offer insights into deep-sea biogeography. During five expeditions between 2009 and 2019, we conducted intensive faunal sampling via 63 submersible dives to 11 localities at depths of 300-3600 m. Based on these expeditions and published literature, we compiled voucher specimens, images, and 274 newly published DNA sequences to present a taxonomic inventory of macrofaunal and megafaunal diversity with a focus on invertebrates. In total 488 morphospecies were identified, representing the highest number of distinct morphospecies published from a single seep or vent region to date. Of these, 131 are described species, at least 58 are undescribed species, and the remainder include some degree of taxonomic uncertainty, likely representing additional undescribed species. Of the described species, 38 are known only from the Costa Rica seeps and their vicinity. Fifteen range extensions are also reported for species known from Mexico, the Galápagos seamounts, Chile, and the western Pacific; as well as 16 new depth records and three new seep records for species known to occur at vents or organic falls. No single evolutionary narrative explains the patterns of biodiversity at these seeps, as even morphologically indistinguishable species can show different biogeographic affinities, biogeographic ranges, or depth ranges. The value of careful molecular taxonomy and comprehensive specimen-based regional inventories is emphasized for biodiversity research and monitoring.
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- 2025
36. Proteome-wide association studies for blood lipids and comparison with transcriptome-wide association studies
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Zhang, Daiwei, Gao, Boran, Feng, Qidi, Manichaikul, Ani, Peloso, Gina M, Tracy, Russell P, Durda, Peter, Taylor, Kent D, Liu, Yongmei, Johnson, W Craig, Gabriel, Stacey, Gupta, Namrata, Smith, Joshua D, Aguet, Francois, Ardlie, Kristin G, Blackwell, Thomas W, Gerszten, Robert E, Rich, Stephen S, Rotter, Jerome I, Scott, Laura J, Zhou, Xiang, and Lee, Seunggeun
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Biological Sciences ,Genetics ,Biotechnology ,Human Genome ,Atherosclerosis ,Prevention ,Heart Disease ,Cardiovascular ,2.1 Biological and endogenous factors ,Generic health relevance ,Good Health and Well Being ,Multi-omics ,blood lipids ,proteome-wide association studies ,transcriptome-wide association studies - Abstract
Blood lipid traits are treatable and heritable risk factors for heart disease, a leading cause of mortality worldwide. Although genome-wide association studies (GWASs) have discovered hundreds of variants associated with lipids in humans, most of the causal mechanisms of lipids remain unknown. To better understand the biological processes underlying lipid metabolism, we investigated the associations of plasma protein levels with total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol in blood. We trained protein prediction models based on samples in the Multi-Ethnic Study of Atherosclerosis (MESA) and applied them to conduct proteome-wide association studies (PWASs) for lipids using the Global Lipids Genetics Consortium (GLGC) data. Of the 749 proteins tested, 42 were significantly associated with at least one lipid trait. Furthermore, we performed transcriptome-wide association studies (TWASs) for lipids using 9,714 gene expression prediction models trained on samples from peripheral blood mononuclear cells (PBMCs) in MESA and 49 tissues in the Genotype-Tissue Expression (GTEx) project. We found that although PWASs and TWASs can show different directions of associations in an individual gene, 40 out of 49 tissues showed a positive correlation between PWAS and TWAS signed p values across all the genes, which suggests high-level consistency between proteome-lipid associations and transcriptome-lipid associations.
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- 2025
37. Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large-vessel occlusion stroke.
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Salim, Hamza, Lakhani, Dhairya, Mei, Janet, Luna, Licia, Shahriari, Mona, Hyson, Nathan, Deng, Francis, Dmytriw, Adam, Guenego, Adrien, Urrutia, Victor, Marsh, Elisabeth, Lu, Hanzhang, Xu, Risheng, Leigh, Rich, Wolman, Dylan, Shah, Gaurang, Pulli, Benjamin, Albers, Gregory, Hillis, Argye, Llinas, Rafael, Nael, Kambiz, Wintermark, Max, Heit, Jeremy, Faizy, Tobias, and Yedavalli, Vivek
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Acute ischemic stroke (AIS) ,Computed tomography perfusion (CTP) ,Intravenous thrombolysis (IVT) ,Large‐vessel occlusion (LVO) ,Mechanical thrombectomy (MT) ,Prolonged venous transit (PVT) ,Venous outflow (VO) ,Humans ,Male ,Female ,Aged ,Middle Aged ,Ischemic Stroke ,Recovery of Function ,Retrospective Studies ,Reperfusion ,Aged ,80 and over ,Cerebrovascular Circulation ,Treatment Outcome - Abstract
BACKGROUND AND PURPOSE: Acute ischemic stroke due to anterior circulation large-vessel occlusion (AIS-LVO) remains a leading cause of disability despite successful reperfusion therapies. Prolonged venous transit (PVT) has emerged as a potential prognostic imaging biomarker in AIS-LVO. We aimed to investigate whether PVT is associated with a decreased likelihood of excellent functional outcome (modified Rankin Scale [mRS] score of 0-1 at 90 days) after successful reperfusion. METHODS: In our prospectively collected, retrospectively reviewed database, we analyzed data from 104 patients with AIS-LVO who achieved successful reperfusion (modified Thrombolysis in Cerebral Infarction score of 2b/2c/3) between September 2017 and September 2022. PVT was defined as a time to maximum (Tmax) of ≥10 s in the superior sagittal sinus and/or torcula on computed tomography perfusion (CTP) imaging. Patients were categorized into PVT-positive (PVT+) and PVT-negative (PVT-) groups. The primary outcome was excellent functional recovery at 90 days. RESULTS: Of the 104 patients, 30 (29%) were PVT+. Excellent functional outcome was achieved in 38 patients (37%). PVT+ patients had a significantly lower rate of excellent recovery compared to PVT- patients (11% vs. 39%; p
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- 2025
38. Analysis of Premature Death Rates in Texas Counties: The Impact of Air Quality, Socioeconomic Factors, and COPD Prevalence
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Rich, Richard and Diaz, Ernesto
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Computer Science - Machine Learning - Abstract
Understanding factors contributing to premature mortality is critical for public health planning. This study examines the relationships between premature death rates and multiple risk factors across several Texas counties, utilizing EPA air quality data, Census information, and county health records from recent years. We analyze the impact of air quality (PM2.5 levels), socioeconomic factors (median household income), and health conditions (COPD prevalence) through statistical analysis and modeling techniques. Results reveal COPD prevalence as a strong predictor of premature death rates, with higher prevalence associated with a substantial increase in years of potential life lost. While socioeconomic factors show a significant negative correlation, air quality demonstrates more complex indirect relationships. These findings emphasize the need for integrated public health interventions that prioritize key health conditions while addressing underlying socioeconomic disparities., Comment: 5 pages
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- 2024
39. Deep view of the intracluster light in the Coma cluster of galaxies
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Jiménez-Teja, Yolanda, Román, Javier, HyeongHan, Kim, Vílchez, Jose M., Dupke, Renato A., Lopes, Paulo Afrânio Augusto, Rich, Robert Michael, Caceres, Osmin, and Li, Chester
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Astrophysics - Astrophysics of Galaxies - Abstract
Detection and study of the intracluster light in rich clusters of galaxies has been a problem of long standing challenge and interest. Using the lowest surface brightness images of the Coma cluster of galaxies in the g and r bands, from the Halos and Environment of Nearby Galaxies (HERON) Coma Cluster Project, we obtained the most extensive image of intracluster light (ICL) in a single cluster to date, spreading over 1.5 Mpc from the cluster core. The unprecedented wealth of spectroscopic data made publicly available by the Dark Energy Spectroscopic Instrument (DESI) Early Data Release, complemented with a compilation from the NASA/IPAC Extragalactic Database and the literature, enabled the identification of 2,157 galaxy members within Coma, from which 42 distinct groups were identified. The synergy between these high-quality data allowed us to: 1) calculate ICL fractions of $19.9\pm0.5$\% and $19.6\pm0.6$\% in the g and r bands, respectively, consistent with a dynamically active cluster, 2) unveil Coma's faintest tidal features, and 3) provide a comprehensive picture of the dynamics and interactions within this complex system. Our findings indicate that the ICL connects several of these groups in a filamentous network, from which we infer the ongoing dynamical processes. In particular, we identified a faint stellar bridge linking the core of Coma with the galaxy NGC 4839, providing compelling evidence that this galaxy has already traversed the central region of the cluster., Comment: 16 pages, 8 figures, 4 tables; accepted for publication in A&A
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- 2024
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40. Cyclotron emitting magnetic white dwarfs in post common envelope binaries discovered with the Zwicky Transient Facility
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van Roestel, J., Rodriguez, A. C., Szkody, P., Brown, A. J., Caiazzo, I., Drake, A., El-Badry, K., Prince, T., Rich, R. M. R., Neill, J. D., Vanderbosch, Z., Bellm, E. C., Dekany, R., Feinstein, F., Graham, M., Groom, S. L., Helou, G., Kulkarni, S. R., Laz, T. du, Mahabal, A., Sharma, Y., Sollerman, J., and Wold, A.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the discovery of 14 new (and recovery of 4 known) low accretion rate magnetic white dwarfs in post-common envelope binaries that emit strong cyclotron emission using the Zwicky Transient Facility (ZTF) light curves, doubling the known sample size. In addition, we discovered a candidate magnetic period bouncer and recovered three known ones. We confirmed the presence of cyclotron emission using low-resolution spectra in 19 objects. Using the ZTF light curves, follow-up spectra, and the spectral energy distribution, we measured the orbital period, magnetic field strength, and white dwarf temperature of each system. Although the phase-folded light curves have diverse shapes and show a much larger variability amplitude, we show that their intrinsic properties (e.g. period distribution, magnetic field strength) are similar to those of previously known systems. The diversity in light curve shapes can be explained by differences in the optical depth of the accretion spot and geometric differences, the inclination angle and the magnetic spot latitude. The evolutionary states of the longer period binaries are somewhat uncertain but are vary; we found systems consistent with being pre-polars, detached polars, or low-state polars. In addition, we discovered two new low-state polars that likely have brown dwarf companions and could be magnetic period bouncers.
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- 2024
41. Behind the dust veil: A panchromatic view of an optically dark galaxy at z=4.82
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Sillassen, Nikolaj B., Jin, Shuowen, Magdis, Georgios E., Hodge, Jacqueline, Gobat, Raphael, Daddi, Emanuele, Knudsen, Kirsten, Finoguenov, Alexis, Schinnerer, Eva, Wang, Wei-Hao, Gao, Zhen-Kai, Weaver, John R., Algera, Hiddo, Andika, Irham T., Brinch, Malte, Chen, Chian-Chou, Cochrane, Rachel, Enia, Andrea, Faisst, Andreas, Gillman, Steven, Gomez-Guijarro, Carlos, Gozaliasl, Ghassem, Hayward, Chris, Kokorev, Vasily, Merchant, Maya, Rizzo, Francesca, Talia, Margherita, Valentino, Francesco, Blánquez-Sesé, David, Koekemoer, Anton M., Magnelli, Benjamin, Rich, Michael, and Shuntov, Marko
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Astrophysics - Astrophysics of Galaxies - Abstract
Optically dark dusty star-forming galaxies (DSFGs) play an essential role in massive galaxy formation at early cosmic time, however their nature remains elusive. Here we present a detailed case study of all the baryonic components of a $z=4.821$ DSFG, XS55. Selected from the ultra-deep COSMOS-XS 3GHz map with a red SCUBA-2 450$\mu$m/850$\mu$m colour, XS55 was followed up with ALMA 3mm line scans and spectroscopically confirmed to be at $z=4.821$ via detections of the CO(5-4) and [CI](1-0) lines. JWST/NIRCam imaging reveals that XS55 is a F150W-dropout with red F277W/F444W colour, and a complex morphology: a compact central component embedded in an extended structure with a likely companion. XS55 is tentatively detected in X-rays with both Chandra and XMM-Newton, suggesting an active galactic nucleus (AGN) nature. By fitting a panchromatic SED spanning NIR to radio wavelengths, we revealed that XS55 is a massive main-sequence galaxy with a stellar mass of $M_\ast=(5\pm1)\times10^{10}\,{\rm M_\odot}$ and a star formation rate of ${\rm SFR}=540\pm177~{\rm M_\odot\,yr^{-1}}$. The dust of XS55 is optically thick in the far infrared (FIR) with a surprisingly cold dust temperature of $T_{\rm dust}=33\pm2\,{\rm K}$, making XS55 one of the coldest DSFGs at $z>4$ known to date. This work unveils the nature of a radio-selected F150W-dropout, suggesting the existence of a population of DSFGs hosting active black holes embedded in optically thick dust., Comment: 11 pages, 7 figures, accepted in Astronomy & Astrophysics
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- 2024
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42. Fault-Tolerant Operation and Materials Science with Neutral Atom Logical Qubits
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Bedalov, Matt. J., Blakely, Matt, Buttler, Peter. D., Carnahan, Caitlin, Chong, Frederic T., Chung, Woo Chang, Cole, Dan C., Goiporia, Palash, Gokhale, Pranav, Heim, Bettina, Hickman, Garrett T., Jones, Eric B., Jones, Ryan A., Khalate, Pradnya, Kim, Jin-Sung, Kuper, Kevin W., Lichtman, Martin T., Lee, Stephanie, Mason, David, Neff-Mallon, Nathan A., Noel, Thomas W., Omole, Victory, Radnaev, Alexander G., Rines, Rich, Saffman, Mark, Shabtai, Efrat, Teo, Mariesa H., Thotakura, Bharath, Tomesh, Teague, and Tucker, Angela K.
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Quantum Physics ,Physics - Atomic Physics - Abstract
We report on the fault-tolerant operation of logical qubits on a neutral atom quantum computer, with logical performance surpassing physical performance for multiple circuits including Bell states (12x error reduction), random circuits (15x), and a prototype Anderson Impurity Model ground state solver for materials science applications (up to 6x, non-fault-tolerantly). The logical qubits are implemented via the [[4, 2, 2]] code (C4). Our work constitutes the first complete realization of the benchmarking protocol proposed by Gottesman 2016 [1] demonstrating results consistent with fault-tolerance. In light of recent advances on applying concatenated C4/C6 detection codes to achieve error correction with high code rates and thresholds, our work can be regarded as a building block towards a practical scheme for fault tolerant quantum computation. Our demonstration of a materials science application with logical qubits particularly demonstrates the immediate value of these techniques on current experiments.
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- 2024
43. Proactive Agents for Multi-Turn Text-to-Image Generation Under Uncertainty
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Hahn, Meera, Zeng, Wenjun, Kannen, Nithish, Galt, Rich, Badola, Kartikeya, Kim, Been, and Wang, Zi
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Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning - Abstract
User prompts for generative AI models are often underspecified, leading to sub-optimal responses. This problem is particularly evident in text-to-image (T2I) generation, where users commonly struggle to articulate their precise intent. This disconnect between the user's vision and the model's interpretation often forces users to painstakingly and repeatedly refine their prompts. To address this, we propose a design for proactive T2I agents equipped with an interface to (1) actively ask clarification questions when uncertain, and (2) present their understanding of user intent as an understandable belief graph that a user can edit. We build simple prototypes for such agents and verify their effectiveness through both human studies and automated evaluation. We observed that at least 90% of human subjects found these agents and their belief graphs helpful for their T2I workflow. Moreover, we develop a scalable automated evaluation approach using two agents, one with a ground truth image and the other tries to ask as few questions as possible to align with the ground truth. On DesignBench, a benchmark we created for artists and designers, the COCO dataset (Lin et al., 2014), and ImageInWords (Garg et al., 2024), we observed that these T2I agents were able to ask informative questions and elicit crucial information to achieve successful alignment with at least 2 times higher VQAScore (Lin et al., 2024) than the standard single-turn T2I generation. Demo: https://github.com/google-deepmind/proactive_t2i_agents.
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- 2024
44. Prism: Semi-Supervised Multi-View Stereo with Monocular Structure Priors
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Rich, Alex, Stier, Noah, Sen, Pradeep, and Höllerer, Tobias
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Computer Science - Computer Vision and Pattern Recognition - Abstract
The promise of unsupervised multi-view-stereo (MVS) is to leverage large unlabeled datasets, yet current methods underperform when training on difficult data, such as handheld smartphone videos of indoor scenes. Meanwhile, high-quality synthetic datasets are available but MVS networks trained on these datasets fail to generalize to real-world examples. To bridge this gap, we propose a semi-supervised learning framework that allows us to train on real and rendered images jointly, capturing structural priors from synthetic data while ensuring parity with the real-world domain. Central to our framework is a novel set of losses that leverages powerful existing monocular relative-depth estimators trained on the synthetic dataset, transferring the rich structure of this relative depth to the MVS predictions on unlabeled data. Inspired by perceptual image metrics, we compare the MVS and monocular predictions via a deep feature loss and a multi-scale statistical loss. Our full framework, which we call Prism, achieves large quantitative and qualitative improvements over current unsupervised and synthetic-supervised MVS networks. This is a best-case-scenario result, opening the door to using both unlabeled smartphone videos and photorealistic synthetic datasets for training MVS networks., Comment: 11 pages, 6 figures, 3 tables
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- 2024
45. Chemical Abundances in the Nuclear Star Cluster of the Milky Way: alpha-Element Trends and Their Similarities with the Inner Bulge
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Ryde, N., Nandakumar, G., Schultheis, M., Kordopatis, G., di Matteo, P., Haywood, M., Schödel, R., Nogueras-Lara, F., Rich, R. M., Thorsbro, B., Mace, G., Agertz, O., Amarsi, A. M., Kocher, J., Molero, M., Origlia, L., Pagnini, G., and Spitoni, E.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
A chemical characterization of the Galactic Center is essential for understanding its formation and structural evolution. Trends of alpha-elements, such as Mg, Si, and Ca, serve as powerful diagnostic tools, offering insights into star-formation rates and gas-infall history. However, high extinction has previously hindered such studies. In this study, we present a detailed chemical abundance analysis of M giants in the Milky Way's Nuclear Star Cluster (NSC), focusing on alpha-element trends with metallicity. High-resolution, near-infrared spectra were obtained using the IGRINS spectrograph on the Gemini South telescope for nine M giants. Careful selection of spectral lines, based on a solar-neighborhood control sample of 50 M giants, was implemented to minimize systematic uncertainties. Our findings show enhanced alpha-element abundances in the predominantly metal-rich NSC stars, consistent with trends in the inner bulge. The NSC stars follow the high-[alpha/Fe] envelope seen in the solar vicinity's metal-rich population, indicating a high star-formation rate. The alpha-element trends decrease with increasing metallicity, also at the highest metallicities. Our results suggest the NSC population likely shares a similar evolutionary history with the inner bulge, challenging the idea of a recent dominant star formation burst. This connection between the NSC and the inner-disk sequence suggests that the chemical properties of extragalactic NSCs of Milky Way type galaxies could serve as a proxy for understanding the host galaxies' evolutionary processes., Comment: Accepted for publication in ApJ
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- 2024
46. Sphere Packing on a Quantum Computer for Chromatography Modeling
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Hall, Benjamin, Njoroge, Ian, Campbell, Colin, Thotakura, Bharath, Rines, Rich, Omole, Victory, and Qadan, Maen
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Quantum Physics - Abstract
Column chromatography is an important process in downstream biopharmaceutical manufacturing that enables high-selectivity separation of proteins through various modalities, such as affinity, ion exchange, hydrophobic interactions, or a combination of the aforementioned modes. Current mechanistic models of column chromatography typically abstract particle-level phenomena, in particular adsorption kinetics. A mechanistic model capable of incorporating particle-level phenomena would increase the value derived from mechanistic models. To this end, we model column chromatography via sphere packing, formulating three versions, each with increasing complexity. The first, homogeneous circle packing, is recast as maximum independent set and solved by the Quantum Approximate Optimization Algorithm on a quantum computer. The second, heterogeneous circle packing, is formulated as a graphical optimization problem and solved via classical simulations, accompanied by a road map to a quantum solution. An extension to the third, heterogeneous sphere packing, is formulated mathematically in a manner suitable to a quantum solution. Finally, detailed resource scaling is conducted to estimate the quantum resources required to simulate the most realistic model, providing a pathway to quantum advantage.
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- 2024
47. The Well: a Large-Scale Collection of Diverse Physics Simulations for Machine Learning
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Ohana, Ruben, McCabe, Michael, Meyer, Lucas, Morel, Rudy, Agocs, Fruzsina J., Beneitez, Miguel, Berger, Marsha, Burkhart, Blakesley, Burns, Keaton, Dalziel, Stuart B., Fielding, Drummond B., Fortunato, Daniel, Goldberg, Jared A., Hirashima, Keiya, Jiang, Yan-Fei, Kerswell, Rich R., Maddu, Suryanarayana, Miller, Jonah, Mukhopadhyay, Payel, Nixon, Stefan S., Shen, Jeff, Watteaux, Romain, Blancard, Bruno Régaldo-Saint, Rozet, François, Parker, Liam H., Cranmer, Miles, and Ho, Shirley
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Computer Science - Machine Learning ,Physics - Fluid Dynamics - Abstract
Machine learning based surrogate models offer researchers powerful tools for accelerating simulation-based workflows. However, as standard datasets in this space often cover small classes of physical behavior, it can be difficult to evaluate the efficacy of new approaches. To address this gap, we introduce the Well: a large-scale collection of datasets containing numerical simulations of a wide variety of spatiotemporal physical systems. The Well draws from domain experts and numerical software developers to provide 15TB of data across 16 datasets covering diverse domains such as biological systems, fluid dynamics, acoustic scattering, as well as magneto-hydrodynamic simulations of extra-galactic fluids or supernova explosions. These datasets can be used individually or as part of a broader benchmark suite. To facilitate usage of the Well, we provide a unified PyTorch interface for training and evaluating models. We demonstrate the function of this library by introducing example baselines that highlight the new challenges posed by the complex dynamics of the Well. The code and data is available at https://github.com/PolymathicAI/the_well., Comment: 38th Conference on Neural Information Processing Systems (NeurIPS 2024) Track on Datasets and Benchmarks
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- 2024
48. DESI 2024 VII: Cosmological Constraints from the Full-Shape Modeling of Clustering Measurements
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DESI Collaboration, Adame, A. G., Aguilar, J., Ahlen, S., Alam, S., Alexander, D. M., Prieto, C. Allende, Alvarez, M., Alves, O., Anand, A., Andrade, U., Armengaud, E., Avila, S., Aviles, A., Awan, H., Bahr-Kalus, B., Bailey, S., Baltay, C., Bault, A., Behera, J., BenZvi, S., Beutler, F., Bianchi, D., Blake, C., Blum, R., Bonici, M., Brieden, S., Brodzeller, A., Brooks, D., Buckley-Geer, E., Burtin, E., Calderon, R., Canning, R., Rosell, A. Carnero, Cereskaite, R., Cervantes-Cota, J. L., Chabanier, S., Chaussidon, E., Chaves-Montero, J., Chebat, D., Chen, S., Chen, X., Claybaugh, T., Cole, S., Cuceu, A., Davis, T. M., Dawson, K., de la Macorra, A., de Mattia, A., Deiosso, N., Dey, A., Dey, B., Ding, Z., Doel, P., Edelstein, J., Eftekharzadeh, S., Eisenstein, D. J., Elbers, W., Elliott, A., Fagrelius, P., Fanning, K., Ferraro, S., Ereza, J., Findlay, N., Flaugher, B., Font-Ribera, A., Forero-Sánchez, D., Forero-Romero, J. E., Frenk, C. S., Garcia-Quintero, C., Garrison, L. H., Gaztañaga, E., Gil-Marín, H., Gontcho, S. Gontcho A, Gonzalez-Morales, A. X., Gonzalez-Perez, V., Gordon, C., Green, D., Gruen, D., Gsponer, R., Gutierrez, G., Guy, J., Hadzhiyska, B., Hahn, C., Hanif, M. M. S, Herrera-Alcantar, H. K., Honscheid, K., Howlett, C., Huterer, D., Iršič, V., Ishak, M., Joyce, R., Juneau, S., Karaçaylı, N. G., Kehoe, R., Kent, S., Kirkby, D., Kong, H., Koposov, S. E., Kremin, A., Krolewski, A., Lahav, O., Lai, Y., Lan, T. -W., Landriau, M., Lang, D., Lasker, J., Goff, J. M. Le, Guillou, L. Le, Leauthaud, A., Levi, M. E., Li, T. S., Lodha, K., Magneville, C., Manera, M., Margala, D., Martini, P., Matthewson, W., Maus, M., McDonald, P., Medina-Varela, L., Meisner, A., Mena-Fernández, J., Miquel, R., Moon, J., Moore, S., Moustakas, J., Mudur, N., Mueller, E., Muñoz-Gutiérrez, A., Myers, A. D., Nadathur, S., Napolitano, L., Neveux, R., Newman, J. A., Nguyen, N. M., Nie, J., Niz, G., Noriega, H. E., Padmanabhan, N., Paillas, E., Palanque-Delabrouille, N., Pan, J., Penmetsa, S., Percival, W. J., Pieri, M. M., Pinon, M., Poppett, C., Porredon, A., Prada, F., Pérez-Fernández, A., Pérez-Ràfols, I., Rabinowitz, D., Raichoor, A., Ramírez-Pérez, C., Ramirez-Solano, S., Rashkovetskyi, M., Ravoux, C., Rezaie, M., Rich, J., Rocher, A., Rockosi, C., Roe, N. A., Rosado-Marin, A., Ross, A. J., Rossi, G., Ruggeri, R., Ruhlmann-Kleider, V., Samushia, L., Sanchez, E., Saulder, C., Schlafly, E. F., Schlegel, D., Schubnell, M., Seo, H., Shafieloo, A., Sharples, R., Silber, J., Slosar, A., Smith, A., Sprayberry, D., Tan, T., Tarlé, G., Taylor, P., Trusov, S., Vaisakh, R., Valcin, D., Valdes, F., Valogiannis, G., Vargas-Magaña, M., Verde, L., Walther, M., Wang, B., Wang, M. S., Weaver, B. A., Weaverdyck, N., Wechsler, R. H., Weinberg, D. H., White, M., Wilson, M. J., Yi, L., Yu, J., Yu, Y., Yuan, S., Yèche, C., Zaborowski, E. A., Zarrouk, P., Zhang, H., Zhao, C., Zhao, R., Zhou, R., Zhuang, T., and Zou, H.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present cosmological results from the measurement of clustering of galaxy, quasar and Lyman-$\alpha$ forest tracers from the first year of observations with the Dark Energy Spectroscopic Instrument (DESI Data Release 1). We adopt the full-shape (FS) modeling of the power spectrum, including the effects of redshift-space distortions, in an analysis which has been validated in a series of supporting papers. In the flat $\Lambda$CDM cosmological model, DESI (FS+BAO), combined with a baryon density prior from Big Bang Nucleosynthesis and a weak prior on the scalar spectral index, determines matter density to $\Omega_\mathrm{m}=0.2962\pm 0.0095$, and the amplitude of mass fluctuations to $\sigma_8=0.842\pm 0.034$. The addition of the cosmic microwave background (CMB) data tightens these constraints to $\Omega_\mathrm{m}=0.3056\pm 0.0049$ and $\sigma_8=0.8121\pm 0.0053$, while further addition of the the joint clustering and lensing analysis from the Dark Energy Survey Year-3 (DESY3) data leads to a 0.4% determination of the Hubble constant, $H_0 = (68.40\pm 0.27)\,{\rm km\,s^{-1}\,Mpc^{-1}}$. In models with a time-varying dark energy equation of state, combinations of DESI (FS+BAO) with CMB and type Ia supernovae continue to show the preference, previously found in the DESI DR1 BAO analysis, for $w_0>-1$ and $w_a<0$ with similar levels of significance. DESI data, in combination with the CMB, impose the upper limits on the sum of the neutrino masses of $\sum m_\nu < 0.071\,{\rm eV}$ at 95% confidence. DESI data alone measure the modified-gravity parameter that controls the clustering of massive particles, $\mu_0=0.11^{+0.45}_{-0.54}$, while the combination of DESI with the CMB and the clustering and lensing analysis from DESY3 constrains both modified-gravity parameters, giving $\mu_0 = 0.04\pm 0.22$ and $\Sigma_0 = 0.044\pm 0.047$, in agreement with general relativity. [Abridged.], Comment: This DESI Collaboration Key Publication is part of the 2024 publication series using the first year of observations (see https://data.desi.lbl.gov/doc/papers/). 55 pages, 10 figures
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- 2024
49. DESI 2024 II: Sample Definitions, Characteristics, and Two-point Clustering Statistics
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DESI Collaboration, Adame, A. G., Aguilar, J., Ahlen, S., Alam, S., Alexander, D. M., Alvarez, M., Alves, O., Anand, A., Andrade, U., Armengaud, E., Avila, S., Aviles, A., Awan, H., Bailey, S., Baltay, C., Bault, A., Behera, J., BenZvi, S., Beutler, F., Bianchi, D., Blake, C., Blum, R., Brieden, S., Brodzeller, A., Brooks, D., Brown, Z., Buckley-Geer, E., Burtin, E., Calderon, R., Canning, R., Rosell, A. Carnero, Cereskaite, R., Cervantes-Cota, J. L., Chabanier, S., Chaussidon, E., Chaves-Montero, J., Chen, S., Chen, X., Claybaugh, T., Cole, S., Cuceu, A., Davis, T. M., Dawson, K., de la Macorra, A., de Mattia, A., Deiosso, N., Demina, R., Dey, A., Dey, B., Ding, Z., Doel, P., Edelstein, J., Eftekharzadeh, S., Eisenstein, D. J., Elliott, A., Fagrelius, P., Fanning, K., Ferraro, S., Ereza, J., Findlay, N., Flaugher, B., Font-Ribera, A., Forero-Sánchez, D., Forero-Romero, J. E., Frenk, C. S., Garcia-Quintero, C., Gaztañaga, E., Gil-Marín, H., Gontcho, S. Gontcho A, Gonzalez-Morales, A. X., Gonzalez-Perez, V., Gordon, C., Green, D., Gruen, D., Gsponer, R., Gutierrez, G., Guy, J., Hadzhiyska, B., Hahn, C., Hanif, M. M. S, Herrera-Alcantar, H. K., Honscheid, K., Hou, J., Howlett, C., Huterer, D., Iršič, V., Ishak, M., Juneau, S., Karaçaylı, N. G., Kehoe, R., Kent, S., Kirkby, D., Kitaura, F. -S., Kong, H., Kremin, A., Krolewski, A., Lai, Y., Lan, T. -W., Landriau, M., Lang, D., Lasker, J., Goff, J. M. Le, Guillou, L. Le, Leauthaud, A., Levi, M. E., Li, T. S., Lodha, K., Magneville, C., Manera, M., Margala, D., Martini, P., Maus, M., McDonald, P., Medina-Varela, L., Meisner, A., Mena-Fernández, J., Miquel, R., Moon, J., Moore, S., Moustakas, J., Mudur, N., Mueller, E., Muñoz-Gutiérrez, A., Myers, A. D., Nadathur, S., Napolitano, L., Neveux, R., Newman, J. A., Nguyen, N. M., Nie, J., Niz, G., Noriega, H. E., Padmanabhan, N., Paillas, E., Palanque-Delabrouille, N., Pan, J., Penmetsa, S., Percival, W. J., Pieri, M. M., Pinon, M., Poppett, C., Porredon, A., Prada, F., Pérez-Fernández, A., Pérez-Ràfols, I., Rabinowitz, D., Raichoor, A., Ramírez-Pérez, C., Ramirez-Solano, S., Rashkovetskyi, M., Ravoux, C., Rezaie, M., Rich, J., Rocher, A., Rockosi, C., Roe, N. A., Rosado-Marin, A., Ross, A. J., Rossi, G., Ruggeri, R., Ruhlmann-Kleider, V., Samushia, L., Sanchez, E., Saulder, C., Schlafly, E. F., Schlegel, D., Scholte, D., Schubnell, M., Seo, H., Sharples, R., Silber, J., Slosar, A., Smith, A., Sprayberry, D., Tan, T., Tarlé, G., Trusov, S., Vaisakh, R., Valcin, D., Valdes, F., Vargas-Magaña, M., Verde, L., Walther, M., Wang, B., Wang, M. S., Weaver, B. A., Weaverdyck, N., Wechsler, R. H., Weinberg, D. H., White, M., Wilson, M. J., Yu, J., Yu, Y., Yuan, S., Yèche, C., Zaborowski, E. A., Zarrouk, P., Zhang, H., Zhao, C., Zhao, R., Zhou, R., and Zou, H.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present the samples of galaxies and quasars used for DESI 2024 cosmological analyses, drawn from the DESI Data Release 1 (DR1). We describe the construction of large-scale structure (LSS) catalogs from these samples, which include matched sets of synthetic reference `randoms' and weights that account for variations in the observed density of the samples due to experimental design and varying instrument performance. We detail how we correct for variations in observational completeness, the input `target' densities due to imaging systematics, and the ability to confidently measure redshifts from DESI spectra. We then summarize how remaining uncertainties in the corrections can be translated to systematic uncertainties for particular analyses. We describe the weights added to maximize the signal-to-noise of DESI DR1 2-point clustering measurements. We detail measurement pipelines applied to the LSS catalogs that obtain 2-point clustering measurements in configuration and Fourier space. The resulting 2-point measurements depend on window functions and normalization constraints particular to each sample, and we present the corrections required to match models to the data. We compare the configuration- and Fourier-space 2-point clustering of the data samples to that recovered from simulations of DESI DR1 and find they are, generally, in statistical agreement to within 2\% in the inferred real-space over-density field. The LSS catalogs, 2-point measurements, and their covariance matrices will be released publicly with DESI DR1., Comment: This DESI Collaboration Key Publication is part of the 2024 publication series using the first year of observations (see https://data.desi.lbl.gov/doc/papers/)
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- 2024
50. DESI 2024 V: Full-Shape Galaxy Clustering from Galaxies and Quasars
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DESI Collaboration, Adame, A. G., Aguilar, J., Ahlen, S., Alam, S., Alexander, D. M., Alvarez, M., Alves, O., Anand, A., Andrade, U., Armengaud, E., Avila, S., Aviles, A., Awan, H., Bailey, S., Baltay, C., Bault, A., Behera, J., BenZvi, S., Beutler, F., Bianchi, D., Blake, C., Blum, R., Brieden, S., Brodzeller, A., Brooks, D., Buckley-Geer, E., Burtin, E., Calderon, R., Canning, R., Rosell, A. Carnero, Cereskaite, R., Cervantes-Cota, J. L., Chabanier, S., Chaussidon, E., Chaves-Montero, J., Chen, S., Chen, X., Claybaugh, T., Cole, S., Cuceu, A., Davis, T. M., Dawson, K., de la Macorra, A., de Mattia, A., Deiosso, N., Dey, A., Dey, B., Ding, Z., Doel, P., Edelstein, J., Eftekharzadeh, S., Eisenstein, D. J., Elliott, A., Fagrelius, P., Fanning, K., Ferraro, S., Ereza, J., Findlay, N., Flaugher, B., Font-Ribera, A., Forero-Sánchez, D., Forero-Romero, J. E., Garcia-Quintero, C., Garrison, L. H., Gaztañaga, E., Gil-Marín, H., Gontcho, S. Gontcho A, Gonzalez-Morales, A. X., Gonzalez-Perez, V., Gordon, C., Green, D., Gruen, D., Gsponer, R., Gutierrez, G., Guy, J., Hadzhiyska, B., Hahn, C., Hanif, M. M. S, Herrera-Alcantar, H. K., Honscheid, K., Howlett, C., Huterer, D., Iršič, V., Ishak, M., Juneau, S., Karaçaylı, N. G., Kehoe, R., Kent, S., Kirkby, D., Kong, H., Koposov, S. E., Kremin, A., Krolewski, A., Lai, Y., Lan, T. -W., Landriau, M., Lang, D., Lasker, J., Goff, J. M. Le, Guillou, L. Le, Leauthaud, A., Levi, M. E., Li, T. S., Lodha, K., Magneville, C., Manera, M., Margala, D., Martini, P., Maus, M., McDonald, P., Medina-Varela, L., Meisner, A., Mena-Fernández, J., Miquel, R., Moon, J., Moore, S., Moustakas, J., Mueller, E., Muñoz-Gutiérrez, A., Myers, A. D., Nadathur, S., Napolitano, L., Neveux, R., Newman, J. A., Nguyen, N. M., Nie, J., Niz, G., Noriega, H. E., Padmanabhan, N., Paillas, E., Palanque-Delabrouille, N., Pan, J., Penmetsa, S., Percival, W. J., Pieri, M. M., Pinon, M., Poppett, C., Porredon, A., Prada, F., Pérez-Fernández, A., Pérez-Ràfols, I., Rabinowitz, D., Raichoor, A., Ramírez-Pérez, C., Ramirez-Solano, S., Rashkovetskyi, M., Ravoux, C., Rezaie, M., Rich, J., Rocher, A., Rockosi, C., Rodríguez-Martínez, F., Roe, N. A., Rosado-Marin, A., Ross, A. J., Rossi, G., Ruggeri, R., Ruhlmann-Kleider, V., Samushia, L., Sanchez, E., Saulder, C., Schlafly, E. F., Schlegel, D., Schubnell, M., Seo, H., Sharples, R., Silber, J., Slosar, A., Smith, A., Sprayberry, D., Tan, T., Tarlé, G., Trusov, S., Vaisakh, R., Valcin, D., Valdes, F., Vargas-Magaña, M., Verde, L., Walther, M., Wang, B., Wang, M. S., Weaver, B. A., Weaverdyck, N., Wechsler, R. H., Weinberg, D. H., White, M., Wilson, M. J., Yu, J., Yu, Y., Yuan, S., Yèche, C., Zaborowski, E. A., Zarrouk, P., Zhang, H., Zhao, C., Zhao, R., Zhou, R., and Zou, H.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present the measurements and cosmological implications of the galaxy two-point clustering using over 4.7 million unique galaxy and quasar redshifts in the range $0.1
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- 2024
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