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3. Assessing the insecticidal effect of Citrus aurantium and Nerium oleander extracts and basalt 'Farina di Basalto®' as biological alternatives to control Aphis punicae and Planococcus citri in an organic pomegranate orchard

Author

Mohamed Elimem, Rym Jaouadi, Thameur Bouslema, Maha Kalboussi, Chaima Lahfef, Slim Rouz, Hassan Kharroubi, Abdennacer Boulila, Sofien Kouki, Giuliano Ragnoni, Gianluca Pizzuti, Fabio Primavera, and Alessandro Riccini

Subjects
basalt, biological control, extracts, efficacy rate, hplc, mortality rate, Plant culture, SB1-1110
Abstract

This study aims to evaluate the efficiency of basalt with two botanical aqueous extracts of Citrus aurantium and Nerium oleander (50g/L) against Aphis punicae and Planococcus citri in an organic pomegranate orchard. Basalt was applied as a foliar spray with two doses (1.5% and 3%), in the ground as a fertiliser (1.5%), and as a combined application (1.5%). Phenolic compounds of both plants were identified by HPLC-PDA/ESI-MS analysis. Seven and six flavonoids were detected in C. aurantium and N. oleander extracts, respectively. Hesperidin was more abundant in C. aurantium extracts; however, N. oleander extracts contained more quercetin rutinoside. A. punicae populations were significantly higher in control trees compared to the treated ones. A. punicae mortality rates reached high values above 90% for basalt and plants extracts and efficacy rates exceeded 80%. P. citri mortality rates reached 88% and 77%, and efficacy rates exceeded 75% and 66% for basalt and plant extracts, respectively. These findings may help to plan Integrated pest management strategies in organic orchards to avoid toxic chemical pesticides.

Published
2023
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4. Drawing/Design: Figuration Configuration Interaction

Author

Raimonda Riccini

Subjects
Drawing. Design. Illustration, NC1-1940, Visual arts, N1-9211
Abstract

"Drawing is not an autonomous reality. It is not: neither as an action nor as the result of an action. What makes drawing a heteronomous reality is its submission to that which is not drawing [Maldonado 1967, p. 217, redactional translation]. The play on words proposed by Vanni Pasca [2010] and, not surprisingly, used as the incipit of the call of this issue of the journal diségno, should be taken very seriously: the relationship between drawing and design as an element for triggering a broader reflection on the two disciplines and their theoretical and practical-operational foundations. [read more]

Published
2022
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6. Peripheral arterial disease has a strong impact on cardiovascular outcome in patients with acute coronary syndromes: from the START Antiplatelet registry

Author

Riccini, C., Cesaro, A., Gragnano, F., Menichelli, D., Pastori, D., Cavallari, I., Denas, G., Zoppellaro, G., Di Serafino, L., De Rosa, G., Grossi, G., Piazzai, C., Gresele, P., Guglielmini, G., Del Pinto, M., Calabrò, P., Pignatelli, P., Patti, G., Pengo, V., Antonucci, E., Cirillo, P., Fierro, T., Palareti, G., and Marcucci, R.

Published
2021
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7. Unattended compared to traditional blood pressure measurement in patients with rheumatoid arthritis: a randomised cross-over study

Author

Elena Bartoloni, Fabio Angeli, Elisa Marcucci, Carlo Perricone, Giacomo Cafaro, Clara Riccini, Lorenzo Spighi, Benedetta Gildoni, Claudio Cavallini, Paolo Verdecchia, and Roberto Gerli

Subjects
Rheumatoid arthritis, hypertension, blood pressure measurement, left ventricular hypertrophy, electrocardiography, echocardiography, Medicine
Abstract

AbstractBackground Hypertension is characterised by a high prevalence, low awareness and poor control among rheumatoid arthritis (RA) patients. Correct blood pressure (BP) measurement is highly important in these subjects. The “unattended” BP measurement aims to reduce the “white-coat effect,” a phenomenon associated with cardiovascular risk. Data on “unattended” BP measurement in RA and its impact on hypertensive organ damage are very limited.Methods BP was measured in the same patient both traditionally (“attended” BP) and by the “unattended” protocol (3 automated office BP measurements, at 1-min intervals, after 5 min of rest, with patient left alone) by a randomised cross-over design. Patients underwent clinical examination, 12-lead electrocardiography and trans-thoracic echocardiography to evaluate cardiac damage.Results Sixty-two RA patients (mean age 67 ± 9 years, 87% women) were enrolled. Hypertension was diagnosed in 79% and 66% of patients according to ACC/AHA and ESC/ESH criteria, respectively. Concordance correlation coefficients between the two techniques were 0.55 (95%, CI 0.38–0.68) for systolic BP and 0.73 (95%, CI 0.60–0.82) for diastolic BP. “Unattended” (121.7/68.6 mmHg) was lower than “attended” BP (130.5/72.8 mmHg) for systolic and diastolic BP (both p

Published
2021
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9. Fast trigger logic with digitized time information

Author

Imbergamo, E., Nappi, A., Papi, A., Riccini, A., and Valdata, M.

Subjects
Physics - Instrumentation and Detectors
Abstract

We present a method for the evaluation, at the first level of trigger, of logical conditions with high time resolution, using the digitized times of fast signals delivered in the detectors of high rate experiments. We describe a dead-time-less implementation of this method on a commercial Field Programmable Gate Array (FPGA). By virtue of its features, the method offers an excellent solution to the problem of including veto conditions in the first level of trigger for experiments on rare decays., Comment: 14 pages with 7 figures, accepted to be published in NIM A

Published
2008
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10. Assessing the insecticidal effect of Citrus aurantium and Nerium oleander extracts and basalt "Farina di Basalto®" as biological alternatives to control Aphis punicae and Planococcus citri in an organic pomegranate orchard

Author

Elimem, Mohamed, primary, Jaouadi, Rym, additional, Bouslema, Thameur, additional, Kalboussi, Maha, additional, Lahfef, Chaima, additional, Rouz, Slim, additional, Kharroubi, Hassan, additional, Boulila, Abdennacer, additional, Kouki, Sofien, additional, Ragnoni, Giuliano, additional, Pizzuti, Gianluca, additional, Primavera, Fabio, additional, and Riccini, Alessandro, additional

Published
2023
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11. Bauhaus

Author

Tomás Maldonado, Raimonda Riccini

Published
2019

15. Diversity and genetic architecture of agro-morphological traits in a core collection of European traditional tomato

Author

Pons, Clara, primary, Casals, Joan, additional, Brower, Matthijs, additional, Sacco, Adriana, additional, Riccini, Alessandro, additional, Hendrickx, Patrick, additional, Figás, Maria del Rosario, additional, Fisher, Josef, additional, Grandillo, Silvana, additional, Mazzucato, Andrea, additional, Soler, Salvador, additional, Zamir, Dani, additional, Causse, Mathilde, additional, Díez, Maria José, additional, Finkers, Richard, additional, Prohens, Jaime, additional, Monforte, Antonio Jose, additional, and Granell, Antonio, additional

Published
2023
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16. Communication and visiting policies in Italian intensive care units during the first COVID-19 pandemic wave and lockdown: a nationwide survey

Author

Langer, T, Depalo, F, Forlini, C, Landini, S, Mezzetti, A, Previtali, P, Monti, G, de Toma, C, Biscardi, D, Giannini, A, Fumagalli, R, Mistraletti, G, Lissoni, B, De Martini, A, Mareto, N, Rossitto, C, Zummo, U, Taverna, M, Machieraldo, P, Navarra, M, Parlanti Garbero, M, Scaletti, C, Perno, S, Amendolia, L, Montrucchio, G, Veliaj, D, Barbarello, G, Alesci, M, Bolgiaghi, L, Vailati, D, Pezzi, A, Boselli, E, Piccoli, F, Greco, M, Gemma, M, Resta, M, Crotti, S, Bottino, N, Abruzzese, C, Savioli, M, Migliorino, G, Muttini, S, Umbrello, M, Borghi, B, Greco, S, Dizeo, M, Bottiroli, M, Mondino, M, Prosepri, M, Casella, G, Curto, F, Zaniboni, M, Giudici, R, Gentile, C, Bombino, M, Rona, R, Cortinovis, B, Benini, A, Avalli, L, Tavola, M, Ferrario, M, Preda, R, Primerano, E, Russo, G, Porta, V, Valdambrini, F, Fassini, P, Orando, S, Beck, E, Pedeferri, M, Cogliati, G, Testini, D, Moroni, B, Codeluppi, V, Ruggeri, P, Milanesi, E, Belliato, M, Besozzi, A, Riccio, M, Zerbi, S, Corbella, D, Ferri, F, Grazioli, L, Bonanomi, E, Giacomini, M, Sacchi, N, Codognola, C, Ambrosini, A, Guatteri, L, Subert, M, Castelli, G, Borelli, M, Venier, E, Dittura, L, Buttera, S, Bigai, R, Magnoni, S, Rauch, S, Colombo, A, Fullin, G, Donolato, C, Cattin, S, State, V, Redeghieri, E, Russo, A, Pastorini, S, Allena, S, Munari, M, Turchet, F, Peta, M, De Santis, V, Scala, C, Facondini, F, Marangoni, E, Tassinati, T, Zanzani, C, Russo, E, Marchio, A, Barbagallo, M, Girardis, M, Taffache, P, Mordacci, M, Vincenzi, M, Pennica, M, Bracciotti, G, Iori, P, Gambi, D, Cappellini, I, Vegnuti, L, De Luca, A, Romagnoli, S, Mosti, G, Carla, R, Roticiani, V, Pelagalli, L, Fuselli, E, D’Avino, E, De Bellis, M, Gianni, G, Leonardis, F, Rossi, M, Lorusso, R, Magnanimi, E, Martelli, S, Baisi, F, Balsamo, D, Cotticelli, V, Mattei, A, Farinelli, I, Riccini, T, Cola, L, Jorio, A, Iacobone, E, Domizi, R, Pizzi, S, Nasso, A, Graziani, R, Monaco, A, Manno, M, Ottelio, C, Del Rio, M, Serra, A, Enna, B, Loddo, F, Galbiati, R, Mellea, S, Kimberly, M, Vissani, M, Romito, F, Baccari, L, Zarrillo, N, Esposito, C, Murino, P, Notaro, S, Ausiello, C, Marra, A, Policastro, C, Cafora, C, De Benedectis, G, Di Falco, V, Sciddurlo, M, Negro, G, Vetuschi, P, Recchia, A, Pasquariello, R, Squillace, R, Ciambrone, A, Bencivenga, C, Camiolo, M, Agozzino, C, Oliveri, F, Notarrigo, T, Castiglione, G, Mo, A, Condorelli, L, Favarato, M, Langer, Thomas, Depalo, Francesca Carmela, Forlini, Clarissa, Landini, Silvia, Mezzetti, Andrea, Previtali, Paola, Monti, Gianpaola, de Toma, Carolina, Biscardi, Davide, Giannini, Alberto, Fumagalli, Roberto, Mistraletti, Giovanni, Lissoni, Barbara, De Martini, Andrea, Mareto, Nadia, Rossitto, Concetta, Zummo, Ugo, Taverna, Martina, Machieraldo, Patrizia, Navarra, Mauro, Parlanti Garbero, Massimiliano, Scaletti, Chiara, Perno, Silvia, Amendolia, Luca, Montrucchio, Giuseppe, Veliaj, Deliana, Barbarello, Giuseppe, Alesci, Maria, Bolgiaghi, Luca, Vailati, Davide, Pezzi, Angelo, Boselli, Enrico, Piccoli, Francesca, Greco, Massimiliano, Gemma, Marco, Resta, Marco, Crotti, Stefania, Bottino, Nicola, Abruzzese, Chiara, Savioli, Monica, Migliorino, Giuseppina, Muttini, Stefano, Umbrello, Michele, Borghi, Beatrice, Greco, Stefano, Dizeo, Micaela, Bottiroli, Maurizio, Mondino, Michele Giovanni, Prosepri, Manlio, Casella, Giampaolo, Curto, Francesco, Zaniboni, Matteo, Giudici, Riccardo, Gentile, Carlo, Bombino, Michela, Rona, Roberto, Cortinovis, Barbara, Benini, Annalisa, Avalli, Leonello, Tavola, Mario, Ferrario, Matteo, Preda, Roberta, Primerano, Enzo, Russo, Gianluca, Porta, Virginia, Valdambrini, Federico, Fassini, Paola, Orando, Serena, Beck, Eduardo, Pedeferri, Matteo, Cogliati, Giacomina, Testini, Denise, Moroni, Benedetta, Codeluppi, Vito, Ruggeri, Patrizia, Milanesi, Elisa, Belliato, Mirko, Besozzi, Alessandra, Riccio, Mario, Zerbi, Silvia, Corbella, Davide, Ferri, Francesco, Grazioli, Lorenzo, Bonanomi, Ezio, Giacomini, Matteo, Sacchi, Noemi, Codognola, Cristian, Ambrosini, Alessandra, Guatteri, Luca, Subert, Matteo, Castelli, Gian Paolo, Borelli, Massimo, Venier, Erica, Dittura, Loredana, Buttera, Stefania, Bigai, Roberto, Magnoni, Sandra, Rauch, Simon, Colombo, Angelo, Fullin, Giorgio, Donolato, Caterina, Cattin, Silvia, State, Veronica, Redeghieri, Enrico, Russo, Alessandro, Pastorini, Simonetta, Allena, Sandra, Munari, Marina, Turchet, Federica, Peta, Mario, De Santis, Vincenzo, Scala, Cristina, Facondini, Francesca, Marangoni, Elisabetta, Tassinati, Tania, Zanzani, Chiara, Russo, Emanuele, Marchio, Annamaria, Barbagallo, Maria, Girardis, Massimo, Taffache, Paolo, Mordacci, Marco, Vincenzi, Matteo, Pennica, Michele, Bracciotti, Giovanna, Iori, Paola, Gambi, Davide, Cappellini, Iacopo, Vegnuti, Lara, De Luca, Alessandra, Romagnoli, Stefano, Mosti, Giamila, Carla, Rossella, Roticiani, Valeria, Pelagalli, Lorella, Fuselli, Ennio, D’Avino, Emilio, De Bellis, Massimo, Gianni, Giulia, Leonardis, Francesca, Rossi, Marzia, Lorusso, Rossana, Magnanimi, Eugenia, Martelli, Sabrina, Baisi, Floriana, Balsamo, Davide, Cotticelli, Virginia, Mattei, Alessia, Farinelli, Ivano, Riccini, Teresa, Cola, Luisanna, Jorio, Antonella, Iacobone, Emanuele, Domizi, Roberta, Pizzi, Simone, Nasso, Armando, Graziani, Romano, Monaco, Anna, Manno, Manuela, Ottelio, Carla Maria, Del Rio, Michela, Serra, Antonio, Enna, Barbara, Loddo, Francesco Marco, Galbiati, Rita, Mellea, Serena, Kimberly, Michelle Brozzi, Vissani, Matteo, Romito, Francesco Massimo, Baccari, Laura, Zarrillo, Nadia, Esposito, Clelia, Murino, Patrizia, Notaro, Salvatore, Ausiello, Carmine, Marra, Annachiara, Policastro, Carmela, Cafora, Chiara, De Benedectis, Giuseppe, Di Falco, Vincenzo, Sciddurlo, Maria, Negro, Giancarlo, Vetuschi, Paolo, Recchia, Andrea, Pasquariello, Rita, Squillace, Rosalba, Ciambrone, Antonio, Bencivenga, Carmela, Camiolo, Melania, Agozzino, Cristina, Oliveri, Francesco, Notarrigo, Tiziana, Castiglione, Giacomo, Mo, Antonella, Condorelli, Laura, Favarato, Martina, Langer, T, Depalo, F, Forlini, C, Landini, S, Mezzetti, A, Previtali, P, Monti, G, de Toma, C, Biscardi, D, Giannini, A, Fumagalli, R, Mistraletti, G, Lissoni, B, De Martini, A, Mareto, N, Rossitto, C, Zummo, U, Taverna, M, Machieraldo, P, Navarra, M, Parlanti Garbero, M, Scaletti, C, Perno, S, Amendolia, L, Montrucchio, G, Veliaj, D, Barbarello, G, Alesci, M, Bolgiaghi, L, Vailati, D, Pezzi, A, Boselli, E, Piccoli, F, Greco, M, Gemma, M, Resta, M, Crotti, S, Bottino, N, Abruzzese, C, Savioli, M, Migliorino, G, Muttini, S, Umbrello, M, Borghi, B, Greco, S, Dizeo, M, Bottiroli, M, Mondino, M, Prosepri, M, Casella, G, Curto, F, Zaniboni, M, Giudici, R, Gentile, C, Bombino, M, Rona, R, Cortinovis, B, Benini, A, Avalli, L, Tavola, M, Ferrario, M, Preda, R, Primerano, E, Russo, G, Porta, V, Valdambrini, F, Fassini, P, Orando, S, Beck, E, Pedeferri, M, Cogliati, G, Testini, D, Moroni, B, Codeluppi, V, Ruggeri, P, Milanesi, E, Belliato, M, Besozzi, A, Riccio, M, Zerbi, S, Corbella, D, Ferri, F, Grazioli, L, Bonanomi, E, Giacomini, M, Sacchi, N, Codognola, C, Ambrosini, A, Guatteri, L, Subert, M, Castelli, G, Borelli, M, Venier, E, Dittura, L, Buttera, S, Bigai, R, Magnoni, S, Rauch, S, Colombo, A, Fullin, G, Donolato, C, Cattin, S, State, V, Redeghieri, E, Russo, A, Pastorini, S, Allena, S, Munari, M, Turchet, F, Peta, M, De Santis, V, Scala, C, Facondini, F, Marangoni, E, Tassinati, T, Zanzani, C, Russo, E, Marchio, A, Barbagallo, M, Girardis, M, Taffache, P, Mordacci, M, Vincenzi, M, Pennica, M, Bracciotti, G, Iori, P, Gambi, D, Cappellini, I, Vegnuti, L, De Luca, A, Romagnoli, S, Mosti, G, Carla, R, Roticiani, V, Pelagalli, L, Fuselli, E, D’Avino, E, De Bellis, M, Gianni, G, Leonardis, F, Rossi, M, Lorusso, R, Magnanimi, E, Martelli, S, Baisi, F, Balsamo, D, Cotticelli, V, Mattei, A, Farinelli, I, Riccini, T, Cola, L, Jorio, A, Iacobone, E, Domizi, R, Pizzi, S, Nasso, A, Graziani, R, Monaco, A, Manno, M, Ottelio, C, Del Rio, M, Serra, A, Enna, B, Loddo, F, Galbiati, R, Mellea, S, Kimberly, M, Vissani, M, Romito, F, Baccari, L, Zarrillo, N, Esposito, C, Murino, P, Notaro, S, Ausiello, C, Marra, A, Policastro, C, Cafora, C, De Benedectis, G, Di Falco, V, Sciddurlo, M, Negro, G, Vetuschi, P, Recchia, A, Pasquariello, R, Squillace, R, Ciambrone, A, Bencivenga, C, Camiolo, M, Agozzino, C, Oliveri, F, Notarrigo, T, Castiglione, G, Mo, A, Condorelli, L, Favarato, M, Langer, Thomas, Depalo, Francesca Carmela, Forlini, Clarissa, Landini, Silvia, Mezzetti, Andrea, Previtali, Paola, Monti, Gianpaola, de Toma, Carolina, Biscardi, Davide, Giannini, Alberto, Fumagalli, Roberto, Mistraletti, Giovanni, Lissoni, Barbara, De Martini, Andrea, Mareto, Nadia, Rossitto, Concetta, Zummo, Ugo, Taverna, Martina, Machieraldo, Patrizia, Navarra, Mauro, Parlanti Garbero, Massimiliano, Scaletti, Chiara, Perno, Silvia, Amendolia, Luca, Montrucchio, Giuseppe, Veliaj, Deliana, Barbarello, Giuseppe, Alesci, Maria, Bolgiaghi, Luca, Vailati, Davide, Pezzi, Angelo, Boselli, Enrico, Piccoli, Francesca, Greco, Massimiliano, Gemma, Marco, Resta, Marco, Crotti, Stefania, Bottino, Nicola, Abruzzese, Chiara, Savioli, Monica, Migliorino, Giuseppina, Muttini, Stefano, Umbrello, Michele, Borghi, Beatrice, Greco, Stefano, Dizeo, Micaela, Bottiroli, Maurizio, Mondino, Michele Giovanni, Prosepri, Manlio, Casella, Giampaolo, Curto, Francesco, Zaniboni, Matteo, Giudici, Riccardo, Gentile, Carlo, Bombino, Michela, Rona, Roberto, Cortinovis, Barbara, Benini, Annalisa, Avalli, Leonello, Tavola, Mario, Ferrario, Matteo, Preda, Roberta, Primerano, Enzo, Russo, Gianluca, Porta, Virginia, Valdambrini, Federico, Fassini, Paola, Orando, Serena, Beck, Eduardo, Pedeferri, Matteo, Cogliati, Giacomina, Testini, Denise, Moroni, Benedetta, Codeluppi, Vito, Ruggeri, Patrizia, Milanesi, Elisa, Belliato, Mirko, Besozzi, Alessandra, Riccio, Mario, Zerbi, Silvia, Corbella, Davide, Ferri, Francesco, Grazioli, Lorenzo, Bonanomi, Ezio, Giacomini, Matteo, Sacchi, Noemi, Codognola, Cristian, Ambrosini, Alessandra, Guatteri, Luca, Subert, Matteo, Castelli, Gian Paolo, Borelli, Massimo, Venier, Erica, Dittura, Loredana, Buttera, Stefania, Bigai, Roberto, Magnoni, Sandra, Rauch, Simon, Colombo, Angelo, Fullin, Giorgio, Donolato, Caterina, Cattin, Silvia, State, Veronica, Redeghieri, Enrico, Russo, Alessandro, Pastorini, Simonetta, Allena, Sandra, Munari, Marina, Turchet, Federica, Peta, Mario, De Santis, Vincenzo, Scala, Cristina, Facondini, Francesca, Marangoni, Elisabetta, Tassinati, Tania, Zanzani, Chiara, Russo, Emanuele, Marchio, Annamaria, Barbagallo, Maria, Girardis, Massimo, Taffache, Paolo, Mordacci, Marco, Vincenzi, Matteo, Pennica, Michele, Bracciotti, Giovanna, Iori, Paola, Gambi, Davide, Cappellini, Iacopo, Vegnuti, Lara, De Luca, Alessandra, Romagnoli, Stefano, Mosti, Giamila, Carla, Rossella, Roticiani, Valeria, Pelagalli, Lorella, Fuselli, Ennio, D’Avino, Emilio, De Bellis, Massimo, Gianni, Giulia, Leonardis, Francesca, Rossi, Marzia, Lorusso, Rossana, Magnanimi, Eugenia, Martelli, Sabrina, Baisi, Floriana, Balsamo, Davide, Cotticelli, Virginia, Mattei, Alessia, Farinelli, Ivano, Riccini, Teresa, Cola, Luisanna, Jorio, Antonella, Iacobone, Emanuele, Domizi, Roberta, Pizzi, Simone, Nasso, Armando, Graziani, Romano, Monaco, Anna, Manno, Manuela, Ottelio, Carla Maria, Del Rio, Michela, Serra, Antonio, Enna, Barbara, Loddo, Francesco Marco, Galbiati, Rita, Mellea, Serena, Kimberly, Michelle Brozzi, Vissani, Matteo, Romito, Francesco Massimo, Baccari, Laura, Zarrillo, Nadia, Esposito, Clelia, Murino, Patrizia, Notaro, Salvatore, Ausiello, Carmine, Marra, Annachiara, Policastro, Carmela, Cafora, Chiara, De Benedectis, Giuseppe, Di Falco, Vincenzo, Sciddurlo, Maria, Negro, Giancarlo, Vetuschi, Paolo, Recchia, Andrea, Pasquariello, Rita, Squillace, Rosalba, Ciambrone, Antonio, Bencivenga, Carmela, Camiolo, Melania, Agozzino, Cristina, Oliveri, Francesco, Notarrigo, Tiziana, Castiglione, Giacomo, Mo, Antonella, Condorelli, Laura, and Favarato, Martina

Abstract

Background: During the first coronavirus disease 2019 (COVID-19) pandemic wave, an unprecedented number of patients with respiratory failure due to a new, highly contagious virus needed hospitalization and intensive care unit (ICU) admission. The aim of the present study was to describe the communication and visiting policies of Italian intensive care units (ICUs) during the first COVID-19 pandemic wave and national lockdown and compare these data with prepandemic conditions. Methods: A national web-based survey was conducted among 290 Italian hospitals. Each ICU (active between February 24 and May 31, 2020) was encouraged to complete an individual questionnaire inquiring the hospital/ICU structure/organization, communication/visiting habits and the role of clinical psychology prior to, and during the first COVID-19 pandemic wave. Results: Two hundred and nine ICUs from 154 hospitals (53% of the contacted hospitals) completed the survey (202 adult and 7 pediatric ICUs). Among adult ICUs, 60% were dedicated to COVID-19 patients, 21% were dedicated to patients without COVID-19 and 19% were dedicated to both categories (Mixed). A total of 11,102 adult patients were admitted to the participating ICUs during the study period and only approximately 6% of patients received at least one visit. Communication with family members was guaranteed daily through an increased use of electronic devices and was preferentially addressed to the same family member. Compared to the prepandemic period, clinical psychologists supported physicians more often regarding communication with family members. Fewer patients received at least one visit from family members in COVID and mixed-ICUs than in non-COVID ICUs, l (0 [0-6]%, 0 [0-4]% and 11 [2-25]%, respectively, p < 0.001). Habits of pediatric ICUs were less affected by the pandemic. Conclusions: Visiting policies of Italian ICUs dedicated to adult patients were markedly altered during the first COVID-19 wave. Remote communication was wi

Published
2022

17. Diversity and genetic architecture of agro-morphological traits in a core collection of European traditional tomato

Author

Pons, Clara, Casals, Joan, Brouwer, Matthijs, Sacco, Adriana, Riccini, Alessandro, Hendrickx, Patrick, del Rosario Figás, Maria, Fisher, Josef, Grandillo, Silvana, Mazzucato, Andrea, Soler, Salvador, Zamir, Dani, Causse, Mathilde, Díez, Maria José, Finkers, Richard, Prohens, Jaime, Monforte, Antonio J., Granell, Antonio, Costa, Fabrizio, Pons, Clara, Casals, Joan, Brouwer, Matthijs, Sacco, Adriana, Riccini, Alessandro, Hendrickx, Patrick, del Rosario Figás, Maria, Fisher, Josef, Grandillo, Silvana, Mazzucato, Andrea, Soler, Salvador, Zamir, Dani, Causse, Mathilde, Díez, Maria José, Finkers, Richard, Prohens, Jaime, Monforte, Antonio J., Granell, Antonio, and Costa, Fabrizio

Abstract

European traditional tomato varieties have been selected by farmers given their consistent performance and adaptation to local growing conditions. Here we developed a multipurpose core collection, comprising 226 accessions representative of the genotypic, phenotypic, and geographical diversity present in European traditional tomatoes, to investigate the basis of their phenotypic variation, gene×environment interactions, and stability for 33 agro-morphological traits. Comparison of the traditional varieties with a modern reference panel revealed that some traditional varieties displayed excellent agronomic performance and high trait stability, as good as or better than that of their modern counterparts. We conducted genome-wide association and genome-wide environment interaction studies and detected 141 quantitative trait loci (QTLs). Out of those, 47 QTLs were associated with the phenotype mean (meanQTLs), 41 with stability (stbQTLs), and 53 QTL-by-environment interactions (QTIs). Most QTLs displayed additive gene actions, with the exception of stbQTLs, which were mostly recessive and overdominant QTLs. Both common and specific loci controlled the phenotype mean and stability variation in traditional tomato; however, a larger proportion of specific QTLs was observed, indicating that the stability gene regulatory model is the predominant one. Developmental genes tended to map close to meanQTLs, while genes involved in stress response, hormone metabolism, and signalling were found within regions affecting stability. A total of 137 marker–trait associations for phenotypic means and stability were novel, and therefore our study enhances the understanding of the genetic basis of valuable agronomic traits and opens up a new avenue for an exploitation of the allelic diversity available within European traditional tomato germplasm.

Published
2023

18. Diversity and genetic architecture of agro-morphological traits in a core collection of European traditional tomato

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de Catalunya. HorPTA - Horticultura: producció, transformació i aprofitament, Pons, Clara, Casals Missio, Joan, Brower, Matthijs, Sacco, Adriana, Riccini, Alessandro, Hendrickx, Patrick, Figàs, Maria de Rosario, Fisher, Joseph, Grandillo, Silvana, Mazzucato, Andrea, Soler Aleixandre, Salvador, Zamir, Dani, Causse, Mathilde, Díez Niclós, María José, Finkers, Richard, Prohens, Jaume, Monforte, Antonio, Granell, Antonio, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de Catalunya. HorPTA - Horticultura: producció, transformació i aprofitament, Pons, Clara, Casals Missio, Joan, Brower, Matthijs, Sacco, Adriana, Riccini, Alessandro, Hendrickx, Patrick, Figàs, Maria de Rosario, Fisher, Joseph, Grandillo, Silvana, Mazzucato, Andrea, Soler Aleixandre, Salvador, Zamir, Dani, Causse, Mathilde, Díez Niclós, María José, Finkers, Richard, Prohens, Jaume, Monforte, Antonio, and Granell, Antonio

Abstract

European traditional tomato varieties have been selected by farmers given their consistent performance and adaptation to local growing conditions. Here we developed a multipurpose core collection, comprising 226 accessions representative of the genotypic, phenotypic, and geographical diversity present in European traditional tomatoes, to investigate the basis of their phenotypic variation, gene×environment interactions, and stability for 33 agro-morphological traits. Comparison of the traditional varieties with a modern reference panel revealed that some traditional varieties displayed excellent agronomic performance and high trait stability, as good as or better than that of their modern counterparts. We conducted genome-wide association and genome-wide environment interaction studies and detected 141 quantitative trait loci (QTLs). Out of those, 47 QTLs were associated with the phenotype mean (meanQTLs), 41 with stability (stbQTLs), and 53 QTL-by-environment interactions (QTIs). Most QTLs displayed additive gene actions, with the exception of stbQTLs, which were mostly recessive and overdominant QTLs. Both common and specific loci controlled the phenotype mean and stability variation in traditional tomato; however, a larger proportion of specific QTLs was observed, indicating that the stability gene regulatory model is the predominant one. Developmental genes tended to map close to meanQTLs, while genes involved in stress response, hormone metabolism, and signalling were found within regions affecting stability. A total of 137 marker–trait associations for phenotypic means and stability were novel, and therefore our study enhances the understanding of the genetic basis of valuable agronomic traits and opens up a new avenue for an exploitation of the allelic diversity available within European traditional tomato germplasm, This work was supported by European Commission H2020 research and innovation program through TRADITOM grant agreement no. 634561, G2P-SOL, grant agreement no. 677379, and HARNESSTOM grant agreement no. 101000716. Networking activities were funded by COST Actions “EUROCAROTEN CA15136 and ‘RoxyCOST’ CA18210 ‘RoxyCOST, Postprint (published version)

Published
2023

19. Trait stability and its genetic basis in European Traditional Tomato

Author

Pons, Clara, Joan Casals, Matthijs Brower, Adriana Sacco, Alessandro Riccini, Patrick Hendrickx, María del Rosario Figás, Josef Fisher, Silvana Grandilloe, Andrea Mazzucatof, Salvador Solera, Dani Zamirg, Mathilde Causseh, María José Díez, Richard Finkers, Jaime Prohens, Monforte, Antonio J., Granell, Antonio, Pons, Clara, Joan Casals, Matthijs Brower, Adriana Sacco, Alessandro Riccini, Patrick Hendrickx, María del Rosario Figás, Josef Fisher, Silvana Grandilloe, Andrea Mazzucatof, Salvador Solera, Dani Zamirg, Mathilde Causseh, María José Díez, Richard Finkers, Jaime Prohens, Monforte, Antonio J., and Granell, Antonio

Published
2023

20. Trait stability and its genetic basis in European traditional tomato

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de Catalunya. HorPTA - Horticultura: producció, transformació i aprofitament, Pons, Clara, Casals Missio, Joan, Brower, Matthijs, Sacco, Adriana, Riccini, Alessandro, Figàs, María Rosario, Fisher, Joseph, Grandillo, Silvana, Mazzucato, Andrea, Soler Aleixandre, Salvador, Zamir, Dani, Causse, Mathilde, Díez Niclós, Maria José, Finkers, Richard, Prohens, Jaume, Monforte, Antonio, Granell, Antoni, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de Catalunya. HorPTA - Horticultura: producció, transformació i aprofitament, Pons, Clara, Casals Missio, Joan, Brower, Matthijs, Sacco, Adriana, Riccini, Alessandro, Figàs, María Rosario, Fisher, Joseph, Grandillo, Silvana, Mazzucato, Andrea, Soler Aleixandre, Salvador, Zamir, Dani, Causse, Mathilde, Díez Niclós, Maria José, Finkers, Richard, Prohens, Jaume, Monforte, Antonio, and Granell, Antoni

Abstract

European traditional tomato varieties have been selected by farmers given their consistent performance and adaptation to local growing conditions. Here we developed a multipurpose core collection, comprising 226 accessions representative of the genotypic, phenotypic and geographical diversity present in European traditional tomatoes, to investigate the basis of their phenotypic variation, G×E interactions and stability for 33 agro-morphological traits. Comparison of the traditional varieties with a modern reference panel revealed that some traditional varieties displayed excellent agronomic performance and high trait stability, as good as or better than that of their modern counterparts. We conducted genome-wide association and genome-wide environment interaction studies and detected 141 quantitative trait loci (QTLs). Out of those, 47 QTLs were associated with the phenotype mean (meanQTLs) and 41 with stability (stbQTLs) and 53 QTL-by-environment interactions (QTIs, Postprint (published version)

Published
2023

22. a

Author

Mohamed Elimem, Rym Jaouadi, Maha Kalboussi, Chaima Lahfef, Slim Rouz, Hassan Kharroubi, Abdennacer Boulila, Sofien Kouki, Giuliano Ragnoni, Gianluca Pizzuti, Fabio Primavera, Alessandro Riccini, and Alberto Cari

Published
2022
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23. Communication and visiting policies in Italian intensive care units during the first COVID-19 pandemic wave and lockdown: a nationwide survey

Author

Langer, Thomas, Depalo, Francesca Carmela, Forlini, Clarissa, Landini, Silvia, Mezzetti, Andrea, Previtali, Paola, Monti, Gianpaola, de Toma, Carolina, Biscardi, Davide, Giannini, Alberto, Fumagalli, Roberto, Mistraletti, Giovanni, Lissoni, Barbara, De Martini, Andrea, Mareto, Nadia, Rossitto, Concetta, Zummo, Ugo, Taverna, Martina, Machieraldo, Patrizia, Navarra, Mauro, Parlanti Garbero, Massimiliano, Scaletti, Chiara, Perno, Silvia, Amendolia, Luca, Montrucchio, Giuseppe, Veliaj, Deliana, Barbarello, Giuseppe, Alesci, Maria, Bolgiaghi, Luca, Vailati, Davide, Pezzi, Angelo, Boselli, Enrico, Piccoli, Francesca, Greco, Massimiliano, Gemma, Marco, Resta, Marco, Crotti, Stefania, Bottino, Nicola, Abruzzese, Chiara, Savioli, Monica, Migliorino, Giuseppina, Muttini, Stefano, Umbrello, Michele, Borghi, Beatrice, Greco, Stefano, Dizeo, Micaela, Bottiroli, Maurizio, Mondino, Michele Giovanni, Prosepri, Manlio, Casella, Giampaolo, Curto, Francesco, Zaniboni, Matteo, Giudici, Riccardo, Gentile, Carlo, Bombino, Michela, Rona, Roberto, Cortinovis, Barbara, Benini, Annalisa, Avalli, Leonello, Tavola, Mario, Ferrario, Matteo, Preda, Roberta, Primerano, Enzo, Russo, Gianluca, Porta, Virginia, Valdambrini, Federico, Fassini, Paola, Orando, Serena, Beck, Eduardo, Pedeferri, Matteo, Cogliati, Giacomina, Testini, Denise, Moroni, Benedetta, Codeluppi, Vito, Ruggeri, Patrizia, Milanesi, Elisa, Belliato, Mirko, Besozzi, Alessandra, Riccio, Mario, Zerbi, Silvia, Corbella, Davide, Ferri, Francesco, Grazioli, Lorenzo, Bonanomi, Ezio, Giacomini, Matteo, Sacchi, Noemi, Codognola, Cristian, Ambrosini, Alessandra, Guatteri, Luca, Subert, Matteo, Castelli, Gian Paolo, Borelli, Massimo, Venier, Erica, Dittura, Loredana, Buttera, Stefania, Bigai, Roberto, Magnoni, Sandra, Rauch, Simon, Colombo, Angelo, Fullin, Giorgio, Donolato, Caterina, Cattin, Silvia, State, Veronica, Redeghieri, Enrico, Russo, Alessandro, Pastorini, Simonetta, Allena, Sandra, Munari, Marina, Turchet, Federica, Peta, Mario, De Santis, Vincenzo, Scala, Cristina, Facondini, Francesca, Marangoni, Elisabetta, Tassinati, Tania, Zanzani, Chiara, Russo, Emanuele, Marchio, Annamaria, Barbagallo, Maria, Girardis, Massimo, Taffache, Paolo, Mordacci, Marco, Vincenzi, Matteo, Pennica, Michele, Bracciotti, Giovanna, Iori, Paola, Gambi, Davide, Cappellini, Iacopo, Vegnuti, Lara, De Luca, Alessandra, Romagnoli, Stefano, Mosti, Giamila, Carla, Rossella, Roticiani, Valeria, Pelagalli, Lorella, Fuselli, Ennio, D’Avino, Emilio, De Bellis, Massimo, Gianni, Giulia, Leonardis, Francesca, Rossi, Marzia, Lorusso, Rossana, Magnanimi, Eugenia, Martelli, Sabrina, Baisi, Floriana, Balsamo, Davide, Cotticelli, Virginia, Mattei, Alessia, Farinelli, Ivano, Riccini, Teresa, Cola, Luisanna, Jorio, Antonella, Iacobone, Emanuele, Domizi, Roberta, Pizzi, Simone, Nasso, Armando, Graziani, Romano, Monaco, Anna, Manno, Manuela, Ottelio, Carla Maria, Del Rio, Michela, Serra, Antonio, Enna, Barbara, Loddo, Francesco Marco, Galbiati, Rita, Mellea, Serena, Kimberly, Michelle Brozzi, Vissani, Matteo, Romito, Francesco Massimo, Baccari, Laura, Zarrillo, Nadia, Esposito, Clelia, Murino, Patrizia, Notaro, Salvatore, Ausiello, Carmine, Marra, Annachiara, Policastro, Carmela, Cafora, Chiara, De Benedectis, Giuseppe, Di Falco, Vincenzo, Sciddurlo, Maria, Negro, Giancarlo, Vetuschi, Paolo, Recchia, Andrea, Pasquariello, Rita, Squillace, Rosalba, Ciambrone, Antonio, Bencivenga, Carmela, Camiolo, Melania, Agozzino, Cristina, Oliveri, Francesco, Notarrigo, Tiziana, Castiglione, Giacomo, Mo, Antonella, Condorelli, Laura, Favarato, Martina, Langer, T, Depalo, F, Forlini, C, Landini, S, Mezzetti, A, Previtali, P, Monti, G, de Toma, C, Biscardi, D, Giannini, A, Fumagalli, R, Mistraletti, G, Lissoni, B, De Martini, A, Mareto, N, Rossitto, C, Zummo, U, Taverna, M, Machieraldo, P, Navarra, M, Parlanti Garbero, M, Scaletti, C, Perno, S, Amendolia, L, Montrucchio, G, Veliaj, D, Barbarello, G, Alesci, M, Bolgiaghi, L, Vailati, D, Pezzi, A, Boselli, E, Piccoli, F, Greco, M, Gemma, M, Resta, M, Crotti, S, Bottino, N, Abruzzese, C, Savioli, M, Migliorino, G, Muttini, S, Umbrello, M, Borghi, B, Greco, S, Dizeo, M, Bottiroli, M, Mondino, M, Prosepri, M, Casella, G, Curto, F, Zaniboni, M, Giudici, R, Gentile, C, Bombino, M, Rona, R, Cortinovis, B, Benini, A, Avalli, L, Tavola, M, Ferrario, M, Preda, R, Primerano, E, Russo, G, Porta, V, Valdambrini, F, Fassini, P, Orando, S, Beck, E, Pedeferri, M, Cogliati, G, Testini, D, Moroni, B, Codeluppi, V, Ruggeri, P, Milanesi, E, Belliato, M, Besozzi, A, Riccio, M, Zerbi, S, Corbella, D, Ferri, F, Grazioli, L, Bonanomi, E, Giacomini, M, Sacchi, N, Codognola, C, Ambrosini, A, Guatteri, L, Subert, M, Castelli, G, Borelli, M, Venier, E, Dittura, L, Buttera, S, Bigai, R, Magnoni, S, Rauch, S, Colombo, A, Fullin, G, Donolato, C, Cattin, S, State, V, Redeghieri, E, Russo, A, Pastorini, S, Allena, S, Munari, M, Turchet, F, Peta, M, De Santis, V, Scala, C, Facondini, F, Marangoni, E, Tassinati, T, Zanzani, C, Russo, E, Marchio, A, Barbagallo, M, Girardis, M, Taffache, P, Mordacci, M, Vincenzi, M, Pennica, M, Bracciotti, G, Iori, P, Gambi, D, Cappellini, I, Vegnuti, L, De Luca, A, Romagnoli, S, Mosti, G, Carla, R, Roticiani, V, Pelagalli, L, Fuselli, E, D’Avino, E, De Bellis, M, Gianni, G, Leonardis, F, Rossi, M, Lorusso, R, Magnanimi, E, Martelli, S, Baisi, F, Balsamo, D, Cotticelli, V, Mattei, A, Farinelli, I, Riccini, T, Cola, L, Jorio, A, Iacobone, E, Domizi, R, Pizzi, S, Nasso, A, Graziani, R, Monaco, A, Manno, M, Ottelio, C, Del Rio, M, Serra, A, Enna, B, Loddo, F, Galbiati, R, Mellea, S, Kimberly, M, Vissani, M, Romito, F, Baccari, L, Zarrillo, N, Esposito, C, Murino, P, Notaro, S, Ausiello, C, Marra, A, Policastro, C, Cafora, C, De Benedectis, G, Di Falco, V, Sciddurlo, M, Negro, G, Vetuschi, P, Recchia, A, Pasquariello, R, Squillace, R, Ciambrone, A, Bencivenga, C, Camiolo, M, Agozzino, C, Oliveri, F, Notarrigo, T, Castiglione, G, Mo, A, Condorelli, L, and Favarato, M

Subjects
Adult, Pandemic, Patient-centered care, Communication, COVID-19, Professional-family relations, Intensive Care Units, Policy, Anesthesiology and Pain Medicine, Health communication, Professional-family relation, Surveys and Questionnaires, Communicable Disease Control, Intensive care units, Pandemics, Humans, Intensive care unit, Child
Abstract

Background During the first coronavirus disease 2019 (COVID-19) pandemic wave, an unprecedented number of patients with respiratory failure due to a new, highly contagious virus needed hospitalization and intensive care unit (ICU) admission. The aim of the present study was to describe the communication and visiting policies of Italian intensive care units (ICUs) during the first COVID-19 pandemic wave and national lockdown and compare these data with prepandemic conditions. Methods A national web-based survey was conducted among 290 Italian hospitals. Each ICU (active between February 24 and May 31, 2020) was encouraged to complete an individual questionnaire inquiring the hospital/ICU structure/organization, communication/visiting habits and the role of clinical psychology prior to, and during the first COVID-19 pandemic wave. Results Two hundred and nine ICUs from 154 hospitals (53% of the contacted hospitals) completed the survey (202 adult and 7 pediatric ICUs). Among adult ICUs, 60% were dedicated to COVID-19 patients, 21% were dedicated to patients without COVID-19 and 19% were dedicated to both categories (Mixed). A total of 11,102 adult patients were admitted to the participating ICUs during the study period and only approximately 6% of patients received at least one visit. Communication with family members was guaranteed daily through an increased use of electronic devices and was preferentially addressed to the same family member. Compared to the prepandemic period, clinical psychologists supported physicians more often regarding communication with family members. Fewer patients received at least one visit from family members in COVID and mixed-ICUs than in non-COVID ICUs, l (0 [0–6]%, 0 [0–4]% and 11 [2–25]%, respectively, p Conclusions Visiting policies of Italian ICUs dedicated to adult patients were markedly altered during the first COVID-19 wave. Remote communication was widely adopted as a surrogate for family meetings. New strategies to favor a family-centered approach during the current and future pandemics are warranted.

Published
2022
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24. 558 BIVENTRICULAR PERIOPERATIVE TAKOTSUBO CARDIOMIOPATHY

Author

Laura Padoan, Stefano Sforna, Antonio Parise, Alberto Barengo, Francesco Torlone, Stefano Coiro, Clara Riccini, Maurizio Del Pinto, and Claudio Cavallini

Subjects
Cardiology and Cardiovascular Medicine
Abstract

Introduction Perioperative Takotsubo cardiomyopathy (pTC) represents a rare and still not well characterized disease. Biventricular involvement is an uncommon manifestation of TC and is associated with a more severe clinical presentation. Case report A 72-year-old male, hospitalized for a laparoscopic left hemicolectomy, was transferred to ICU after having developed severe bradycardia, treated with Adrenalin, and cardiogenic shock during induction of general anesthesia. EKG showed complete atrio-ventricular block, so a temporary PMK was placed. Troponin was raised. Echocardiogram showed severe biventricular disfunction (LVEF 25%, TAPSE 12 mm) with akinesia of medio-apical segments, suggesting a biventricular pTC. Also, there was a reduction of 3D LV longitudinal strain (- 5,8%), particularly of the medio-apical portion, and RV free wall longitudinal strain (- 11%). Coronary angiography resulted negative. Patient's hemodynamic was supported with Noradrenalin and a cycle of Levosimendan, allowing to reach stability. Further echocardiogram showed improvement of biventricular function and longitudinal strain values. Due to the persistency of atrio-ventricular block, a definitive PMK was placed. Patient was discharged after therapy optimization. Discussion pTC is a little-known disease, as incidence and etiology are not well definite. Literature suggests a relation between pTC and physical or emotional stress due to surgery to promote an increase of catecholamine release. Other potential factors may be inadequate depth of anesthesia or tracheal manipulation during intubation and catecholaminergic drugs administration. On the other hand, the use of anesthetic volatile agents seems to have a cardioprotective effect. PTC is more common during general anesthesia and when occurs intraoperatively has a worse clinical presentation. Biventricular involvement, which is a rare and severe manifestation of TC, has been reported frequently among pTC patients. To date, due to the lack of a systematic review, there is little knowledge about potential risk factors, prevention strategies and management of pTC. Conclusions Despite multiple cases of pTC have been reported, several characteristics of this entity are not fully understood. However, it must be considered as a part of differential diagnosis in patients with anaesthesia-related decompensation. Biventricular involvement represents an infrequent presentation and its commonly associated with life-threating hemodynamic impairment.

Published
2022
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25. 558 BIVENTRICULAR PERIOPERATIVE TAKOTSUBO CARDIOMIOPATHY

Author

Padoan, Laura, primary, Sforna, Stefano, additional, Parise, Antonio, additional, Barengo, Alberto, additional, Torlone, Francesco, additional, Coiro, Stefano, additional, Riccini, Clara, additional, Del Pinto, Maurizio, additional, and Cavallini, Claudio, additional

Published
2022
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26. Soluble CD40 ligand and outcome in patients with coronary artery disease undergoing percutaneous coronary intervention

Author

Clara Riccini, Sara Cavallini, Andrea Santucci, Claudio Cavallini, Stefano Savonitto, Paolo Verdecchia, Rocco Sclafani, Stefano De Servi, Stefano Coiro, and Fabio Angeli

Subjects
Male, medicine.medical_specialty, angioplasty, atherosclerosis, chronic disease, inflammation, myocardial infarction, soluble CD40 ligand, medicine.medical_treatment, CD40 Ligand, Clinical Biochemistry, Coronary Artery Disease, Coronary artery disease, Percutaneous Coronary Intervention, Restenosis, Internal medicine, Angioplasty, medicine, Humans, Myocardial infarction, Acute Coronary Syndrome, Angioplasty, Balloon, Coronary, Aged, business.industry, Biochemistry (medical), Hazard ratio, Percutaneous coronary intervention, Thrombosis, General Medicine, Middle Aged, medicine.disease, Conventional PCI, Cardiology, Female, business
Abstract

Objectives CD40 ligand (CD40L), a transmembrane glycoprotein belonging to the tumor necrosis factor family and expressed by a variety of cells, is involved in the basic mechanisms of inflammation, atherosclerosis and thrombosis. Some studies suggest that the soluble form of CD40L (sCD40L) is a predictor of major cardiovascular events and mortality in a variety of clinical settings, but data from literature are conflicting. Methods We studied consecutive patients with acute (ACS) or chronic (CCS) coronary syndrome who underwent percutaneous coronary artery intervention (PCI). Blood samples for sCD40L dosage were taken at baseline immediately before PCI. We tested the relation between sCD40L and pre-specified outcome measures consisting of new ACS, clinical restenosis and all-cause mortality. We recruited 3,841 patients (mean age 64 ± 11 years, 79% men) with ACS (n=2,383) or CCS (n=1,458). Results During a mean follow-up of two years (±0.6 years), 642 patients developed ACS, 409 developed restenosis (≥70% of at least one of the previously treated coronary segments) and 175 died. For each 1-standard deviation increase in sCD40L (0.80 ng/mL), the hazard ratios (HRs) for ACS, restenosis, and mortality were 1.11 (95% confidence interval [CI]: 1.05 to 1.18, p Conclusions Among patients with ACS or CCS who undergo PCI, higher levels of sCD40L predict an increased risk of acute coronary events and coronary restenosis, but not of mortality.

Published
2021
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27. Unattended compared to traditional blood pressure measurement in patients with rheumatoid arthritis: a randomised cross-over study

Author

Elisa Marcucci, Lorenzo Spighi, Benedetta Gildoni, Clara Riccini, Elena Bartoloni, Fabio Angeli, Giacomo Cafaro, Claudio Cavallini, Carlo Perricone, Roberto Gerli, and Paolo Verdecchia

Subjects
Male, medicine.medical_specialty, hypertension, blood pressure measurement, Concordance, electrocardiography, Diastole, Physical examination, Blood Pressure, Left ventricular hypertrophy, echocardiography, left ventricular hypertrophy, Rheumatoid arthritis, Arthritis, Rheumatoid, Internal medicine, medicine, Humans, Aged, Aged, 80 and over, Cross-Over Studies, medicine.diagnostic_test, business.industry, Age Factors, Reproducibility of Results, Blood Pressure Determination, General Medicine, Middle Aged, medicine.disease, Crossover study, Blood pressure, Cardiovascular Diseases, Cardiology, Female, business, Cardiology & Cardiovascular Disorders, Electrocardiography, White Coat Hypertension, Research Article
Abstract

Background Hypertension is characterised by a high prevalence, low awareness and poor control among rheumatoid arthritis (RA) patients. Correct blood pressure (BP) measurement is highly important in these subjects. The “unattended” BP measurement aims to reduce the “white-coat effect,” a phenomenon associated with cardiovascular risk. Data on “unattended” BP measurement in RA and its impact on hypertensive organ damage are very limited. Methods BP was measured in the same patient both traditionally (“attended” BP) and by the “unattended” protocol (3 automated office BP measurements, at 1-min intervals, after 5 min of rest, with patient left alone) by a randomised cross-over design. Patients underwent clinical examination, 12-lead electrocardiography and trans-thoracic echocardiography to evaluate cardiac damage. Results Sixty-two RA patients (mean age 67 ± 9 years, 87% women) were enrolled. Hypertension was diagnosed in 79% and 66% of patients according to ACC/AHA and ESC/ESH criteria, respectively. Concordance correlation coefficients between the two techniques were 0.55 (95%, CI 0.38–0.68) for systolic BP and 0.73 (95%, CI 0.60–0.82) for diastolic BP. “Unattended” (121.7/68.6 mmHg) was lower than “attended” BP (130.5/72.8 mmHg) for systolic and diastolic BP (both p

Published
2021

28. INSECTICIDAL IMPACT OF AQUEOUS PLANT EXTRACTS (CAROB, OLEANDER, ALEPPO PINE AND BITTER ORANGE) AND BASALT FLOUR "FARINA DI BASALTO® XF AND XM" AS A BIOLOGICAL SOLUTION TO CONTROL CEREAL PESTS.

Author

Lahfef, Chaima, Elimem, Mohamed, Jaouadi, Rym, Cyrine, Jalel, Lebdi-Grissa, Kaouthar, Rouz, Slim, Pizzuti, Gianluca, Primavera, Fabio, Ruggeri, Federica, Riccini, Alessandro, and Ragnoni, Giuliano

Abstract

Integrated pest management of cereal crops uses all necessary methods to reduce pest populations. These methods: such as plants' aqueous extracts, are usually efficient, economical, and respectful towards the environment. These products are used to control pests and evaluate their effect on cereal plants. The experiment was conducted in a barley field. The bioinsecticides tested were the aqueous extracts of four vegetal plants (Carob, oleander, Aleppo pine, and bitter orange) and basalt flour "Farina di Basalto® Type XF and Type XM" as mineral material. The tested doses were in order of 5% and 1,5% for plants and basalt aqueous extracts respectively. They were tested against aphids, thrips, and cereal leaf beetles. The experimental design was a complete random block (CRB). Every treatment had 3 replicates, and their distribution was random. The morphometric parameters (roots weight and length, stem length and leaf area), efficiency and mortality rates were calculated to evaluate the effect of the different products on cereal plants and pests. The tested aqueous extracts were not toxic towards plants. Thus, the morphometric parameters showed that the plant development was normal during the management such as the control. All aqueous extracts were efficient in pest management by reducing their populations. For basaltic extracts, foliar (XF - "Farina di Basalto® Type XF") was lethal for thrips and cereal leaf beetles by around 70% and combined (XM - "Farina di Basalto® Type XM" and XF "Farina di Basalto® Type XF") for thrips and aphids by 75.20 and 34.66% respectively. For botanical extract, carob (Cs) was toxic against thrips and aphid by 73.39 and 44.21% respectively and oleander (NeO) was relevant against thrips and cereal leaf beetles by 76.94 and 36.67% respectively. For cereal leaf beetles, the aqueous extracts helped to mitigate their leaves' damage. Using plants and mineral powder is not only an effective method for pest management but also a friendly alternative, especially since it has lower toxicity against cereal plants. [ABSTRACT FROM AUTHOR]

Published
2023

29. European traditional tomatoes galore: a result of farmers' selection of a few diversity-rich loci

Author

Blanca, Jose, Pons, Clara, Montero-Pau, Javier, Sanchez-Matarredona, David, Ziarsolo, Peio, Fontanet, Lilian, Fisher, Josef, Plazas, Mariola, Casals, Joan, Rambla, Jose Luis, Riccini, Alessandro, Pombarella, Samuela, Ruggiero, Alessandra, Sulli, Maria, Grillo, Stephania, Kanellis, Angelos, Giuliano, Giovanni, Finkers, Richard, Cammareri, Maria, Grandillo, Silvana, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaime, Zamir, Dani, Cañizares, Joaquin, Monforte, Antonio Jose, Granell, Antonio, Vicente, Ariel, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de València (UPV), Génétique et Amélioration des Fruits et Légumes (GAFL), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), The Hebrew University of Jerusalem (HUJ), Barcelona School of Agricultural Engineering, Instituto de Biología Molecular y Celular de Plantas (IBMCP), Universitat Politècnica de València (UPV)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Università degli studi della Tuscia [Viterbo], National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), University of Naples Federico II = Università degli studi di Napoli Federico II, Agenzia Nazionale per le nuove Tecnologie, l’energia e lo sviluppo economico sostenibile = Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Aristotle University of Thessaloniki, Casaccia Research Center, Wageningen University and Research [Wageningen] (WUR), European Project: 634561,H2020,H2020-SFS-2014-2,TRADITOM(2015), Blanca, J., Pons, C., Montero-Pau, J., Sanchez-Matarredona, D., Ziarsolo, P., Fontanet, L., Fisher, J., Plazas, M., Casals, J., Rambla, J. L., Riccini, A., Pombarella, S., Ruggiero, A., Sulli, M., Grillo, S., Kanellis, A., Giuliano, G., Finkers, R., Cammareri, M., Grandillo, S., Mazzucato, A., Causse, M., Diez, M. J., Prohens, J., Zamir, D., Canizares, J., Monforte, A. J., and Granell, A.

Subjects
LD, QTL, Physiology, SLC, Fruit morphology, Microbiologia, Plant Science, Portes-lès-Valence, SLL, quantitative trait locus, Solanum lycopersicum, single nucleotide polymorphism, Crop evolution, diversification, fruit morphology, genome-wide association study, genotyping by sequencing, selection, GWAS, LSL, Solanum pimpinellifolium HM Clause, Farmers, SP, Solanum lycopersicum var. cerasiforme, Tomàquets--Conreu, minimum allele frequency, MAF, Phenotype, Diversification, Genotyping by sequencing, long shelf-life, Genome-wide association study, SNP, principal coordinate analyses, GBS, France Crop evolution, Polymorphism, Single Nucleotide, Life Science, Humans, PCoA, Enginyeria agroalimentària::Agricultura::Producció vegetal [Àrees temàtiques de la UPC], Selection, Alleles, Genetic Variation, Ecologia, [SDV.BV.AP]Life Sciences [q-bio]/Vegetal Biology/Plant breeding, Plant Breeding, Solanum lycopersicum L. var. lycopersicum, linkage disequilibrium, Tomatoes--Varieties, Genome-Wide Association Study
Abstract

A comprehensive collection of 1254 tomato accessions, corresponding to European traditional and modern varieties, early domesticated varieties, and wild relatives, was analyzed by genotyping by sequencing. A continuous genetic gradient between the traditional and modern varieties was observed. European traditional tomatoes displayed very low genetic diversity, with only 298 polymorphic loci (95% threshold) out of 64 943 total variants. European traditional tomatoes could be classified into several genetic groups. Two main clusters consisting of Spanish and Italian accessions showed higher genetic diversity than the remaining varieties, suggesting that these regions might be independent secondary centers of diversity with a different history. Other varieties seem to be the result of a more recent complex pattern of migrations and hybridizations among the European regions. Several polymorphic loci were associated in a genome-wide association study with fruit morphological traits in the European traditional collection. The corresponding alleles were found to contribute to the distinctive phenotypic characteristic of the genetic varietal groups. The few highly polymorphic loci associated with morphological traits in an otherwise a low-diversity population suggests a history of balancing selection, in which tomato farmers likely maintained the morphological variation by inadvertently applying a high selective pressure within different varietal types.

Published
2022
Full Text
View/download PDF

31. Treatment of stable ischaemic heart disease: the old and the new

Author

Andrea Santucci, Clara Riccini, and Claudio Cavallini

Subjects
Stable angina, medicine.medical_specialty, medicine.drug_class, Ranolazine, 030204 cardiovascular system & hematology, Angina, 03 medical and health sciences, 0302 clinical medicine, Pharmacotherapy, Internal medicine, medicine, 030212 general & internal medicine, Myocardial infarction, Aspirin, Ischaemic heart disease, business.industry, Secondary prevention, Anticoagulant, Antagonist, Articles, medicine.disease, Cardiology, Cardiology and Cardiovascular Medicine, business, Ivabradine, medicine.drug
Abstract

Stable ischaemic heart disease is a frequent and very heterogeneous condition. Drug therapy is important, in these patients, for improving their prognosis and controlling their symptoms. The typical clinical manifestation of obstructive coronary disease is angina pectoris. This symptom can be improved by various classes of compounds, namely beta-blockers (BBs), calcium antagonist, and nitrates. More recently, ranolazine and ivabradine have been introduced. All these drugs have been proven to reduce significantly angina. On the other hand, there are no evidences supporting improvement in prognosis, besides for the use of BBs, in patients with previous myocardial infarction (MI) or systolic dysfunction. Besides drugs for symptoms control, these patients also receive antiplatelet drugs, specifically aspirin, and lipid lowering compounds such as statins. Furthermore, recent evidences supported the use of low doses direct anticoagulant, or a second antiplatelet agent in patients with previous MI. Similarly, a very low LDL cholesterol level, such as obtained with PCKS9 inhibitors, seems very beneficial in these patients. It is possible that in the near future a specific role for neo-angiogenesis factors and cellular therapies, could be proven, albeit, presently these treatments are not supported by solid evidences.

Published
2020
Full Text
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32. Atlas of phenotypic, genotypic and geographical diversity present in the European traditional tomato

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Pons, Clara, Casals Missio, Joan, Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandro, Figàs, Maria de Rosario, Plazas, Mariola, Koukounaras, Athanasios, Picarella, Maurizio E, Sulli, Maria, Fisher, Joseph, Ziarsolo, Pietro, Blanca, José, Cañizares, Joaquin, Cammareri, M, Vitiello, A, Batelli, Giorgia, Kanellis, Angelos, Brower, Matthijs, Finkers, Richard, Nikoloudis, Konstantinos, Soler Aleixandre, Salvador, Giuliano, Giovani, Grillo, Stephania, Grandillo, Silvana, Zamir, Dani, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaume, Monforte, Antonio, Granell, Antoni, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Pons, Clara, Casals Missio, Joan, Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandro, Figàs, Maria de Rosario, Plazas, Mariola, Koukounaras, Athanasios, Picarella, Maurizio E, Sulli, Maria, Fisher, Joseph, Ziarsolo, Pietro, Blanca, José, Cañizares, Joaquin, Cammareri, M, Vitiello, A, Batelli, Giorgia, Kanellis, Angelos, Brower, Matthijs, Finkers, Richard, Nikoloudis, Konstantinos, Soler Aleixandre, Salvador, Giuliano, Giovani, Grillo, Stephania, Grandillo, Silvana, Zamir, Dani, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaume, Monforte, Antonio, and Granell, Antoni

Abstract

The Mediterranean basin countries are considered secondary centres of tomato diversification. However, information on phenotypic and allelic variation of local tomato materials is still limited. Here we report on the evaluation of the largest traditional tomato collection, which includes 1499 accessions from Southern Europe. Analyses of 70 traits revealed a broad range of phenotypic variability with different distributions among countries, with the culinary end use within each country being the main driver of tomato diversification. Furthermore, eight main tomato types (phenoclusters) were defined by integrating phenotypic data, country of origin, and end use. Genome-wide association study (GWAS) meta-analyses identified associations in 211 loci, 159 of which were novel. The multidimensional integration of phenoclusters and the GWAS meta-analysis identified the molecular signatures for each traditional tomato type and indicated that signatures originated from differential combinations of loci, which in some cases converged in the same tomato phenotype. Our results provide a roadmap for studying and exploiting this untapped tomato diversity., We thank Universitat Illes Balears, the Greek Gene Bank (GGB-NAGREF), Università degli Studi Mediterranea Reggio Calabria, the CRB-Leg (INRA-GAFL)”, the Genebank of CNR-IBBR (Bari, Italy) and ARCA 2010 for seed sharing. CNR-IBBR also acknowledges the seed donors, the Leibniz Institute of Plant Genetics and Crop Plant Research, Maria Cristina Patané (CNR-IBE, Catania, Italy) and La Semiorto Sementi SRL, as well as Mrs. Roberta Nurcato for technical assistance. IBMCP-UPV acknowledges Maurizio CWe thank Universitat Illes Balears, the Greek Gene Bank (GGB-NAGREF), Università degli Studi Mediterranea Reggio Calabria, the CRB-Leg (INRA-GAFL)”, the Genebank of CNR-IBBR (Bari, Italy) and ARCA 2010 for seed sharing. CNR-IBBR also acknowledges the seed donors, the Leibniz Institute of Plant Genetics and Crop Plant Research, Maria Cristina Patané (CNR-IBE, Catania, Italy) and La Semiorto Sementi SRL, as well as Mrs. Roberta Nurcato for technical assistance. IBMCP-UPV acknowledges Maurizio Calduch (ALCALAX) for technical assistance and Mario Fon for English grammar editing. This work was supported by European Commission H2020 research and innovation program through TRADITOM grant agreement No.634561, G2P-SOL, grant agreement No. 677379, and HARNESSTOM grant agreement No. 101000716. Clara Pons and Mariola Plazas are grateful to Spanish Ministerio de Ciencia e Innovación for postdoctoral grants FJCI-2016-29118 and IJC2019-039091-I/AEI/10.13039/501100011033; Joan Casals to a Serra Húnter Fellow at Universistat Politècnica de Catalunya.alduch (ALCALAX) for technical assistance and Mario Fon for English grammar editing. This work was supported by European Commission H2020 research and innovation program through TRADITOM grant agreement No.634561, G2P-SOL, grant agreement No. 677379, and HARNESSTOM grant agreement No. 101000716. Clara Pons and Mariola Plazas are grateful to Spanish Ministerio de Ciencia e Innovación for postdoctoral grants FJCI-2016-29118 and IJC2019-039091-I/AEI/10., Postprint (published version)

Published
2022

33. Atlas of phenotypic, genotypic and geographical diversity present in the European traditional tomato

Author

Pons, Clara, Casals, Joan, Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandra, Figás, Maria Del Rosario, Plazas, Mariola, Koukounaras, Athanasios, Picarella, Maurizio E, Sulli, Maria, Fisher, Josef, Ziarsolo, Peio, Blanca, Jose, Cañizares, Joaquin, Cammareri, Maria, Vitiello, Antonella, Batelli, Giorgia, Kanellis, Angelos, Brouwer, Matthijs, Finkers, Richard, Nikoloudis, Konstantinos, Soler, Salvador, Giuliano, Giovanni, Grillo, Stephania, Grandillo, Silvana, Zamir, Dani, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaime, Monforte, Antonio Jose, Granell, Antonio, Pons, Clara, Casals, Joan, Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandra, Figás, Maria Del Rosario, Plazas, Mariola, Koukounaras, Athanasios, Picarella, Maurizio E, Sulli, Maria, Fisher, Josef, Ziarsolo, Peio, Blanca, Jose, Cañizares, Joaquin, Cammareri, Maria, Vitiello, Antonella, Batelli, Giorgia, Kanellis, Angelos, Brouwer, Matthijs, Finkers, Richard, Nikoloudis, Konstantinos, Soler, Salvador, Giuliano, Giovanni, Grillo, Stephania, Grandillo, Silvana, Zamir, Dani, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaime, Monforte, Antonio Jose, and Granell, Antonio

Abstract

The Mediterranean basin countries are considered secondary centres of tomato diversification. However, information on phenotypic and allelic variation of local tomato materials is still limited. Here we report on the evaluation of the largest traditional tomato collection, which includes 1499 accessions from Southern Europe. Analyses of 70 traits revealed a broad range of phenotypic variability with different distributions among countries, with the culinary end use within each country being the main driver of tomato diversification. Furthermore, eight main tomato types (phenoclusters) were defined by integrating phenotypic data, country of origin, and end use. Genome-wide association study (GWAS) meta-analyses identified associations in 211 loci, 159 of which were novel. The multidimensional integration of phenoclusters and the GWAS meta-analysis identified the molecular signatures for each traditional tomato type and indicated that signatures originated from differential combinations of loci, which in some cases converged in the same tomato phenotype. Our results provide a roadmap for studying and exploiting this untapped tomato diversity.

Published
2022

34. European traditional tomatoes galore: a result of farmers' selection of a few diversity-rich loci

Author

0000-0002-0864-8157, 0000-0002-2486-0510, 0000-0002-4368-8058, 0000-0002-0407-4985, 0000-0003-3461-3094, 0000-0003-4266-9581, Blanca, Jose, Pons, Clara, Montero-Pau, Javier, Sanchez-Matarredona, David, Ziarsolo, Peio, Fontanet, Lilian, Fisher, Josef, Plazas, Mariola, Casals, Joan, Rambla, José Luis, Riccini, Alessandro, Pombarella, Samuela, Ruggiero, Alessandra, Sulli, Maria, Grillo, Stephania, Kanellis, Angelos, Giuliano, Giovanni, Finkers, Richard, Cammareri, Maria, Grandillo, Silvana, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaime, Zamir, Dani, Cañizares, Joaquin, Monforte, Antonio Jose, Granell, Antonio, 0000-0002-0864-8157, 0000-0002-2486-0510, 0000-0002-4368-8058, 0000-0002-0407-4985, 0000-0003-3461-3094, 0000-0003-4266-9581, Blanca, Jose, Pons, Clara, Montero-Pau, Javier, Sanchez-Matarredona, David, Ziarsolo, Peio, Fontanet, Lilian, Fisher, Josef, Plazas, Mariola, Casals, Joan, Rambla, José Luis, Riccini, Alessandro, Pombarella, Samuela, Ruggiero, Alessandra, Sulli, Maria, Grillo, Stephania, Kanellis, Angelos, Giuliano, Giovanni, Finkers, Richard, Cammareri, Maria, Grandillo, Silvana, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaime, Zamir, Dani, Cañizares, Joaquin, Monforte, Antonio Jose, and Granell, Antonio

Abstract

A comprehensive collection of 1254 tomato accessions, corresponding to European traditional and modern varieties, early domesticated varieties, and wild relatives, was analyzed by genotyping by sequencing. A continuous genetic gradient between the traditional and modern varieties was observed. European traditional tomatoes displayed very low genetic diversity, with only 298 polymorphic loci (95% threshold) out of 64 943 total variants. European traditional tomatoes could be classified into several genetic groups. Two main clusters consisting of Spanish and Italian accessions showed higher genetic diversity than the remaining varieties, suggesting that these regions might be independent secondary centers of diversity with a different history. Other varieties seem to be the result of a more recent complex pattern of migrations and hybridizations among the European regions. Several polymorphic loci were associated in a genome-wide association study with fruit morphological traits in the European traditional collection. The corresponding alleles were found to contribute to the distinctive phenotypic characteristic of the genetic varietal groups. The few highly polymorphic loci associated with morphological traits in an otherwise a low-diversity population suggests a history of balancing selection, in which tomato farmers likely maintained the morphological variation by inadvertently applying a high selective pressure within different varietal types.

Published
2022

35. Unlocking the European traditional tomato genetic resources

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandro, Figàs, María del Rosario, Plazas, Mariola, Ziarsolo, Pietro, Casals Missio, Joan, Mazzucato, Andrea, Prohens, Jaume, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandro, Figàs, María del Rosario, Plazas, Mariola, Ziarsolo, Pietro, Casals Missio, Joan, Mazzucato, Andrea, and Prohens, Jaume

Abstract

The Mediterranean basin countries are considered secondary centres of tomato diversification. However, information on phenotypic and allelic variation of local tomato materials is still limited. To unveil the molecular basis of Southern European tomato phenotypic diversity, we carried out the most comprehensive phenotypic and genomic variability analysis on traditional European tomato by using 1) a collection of 1,499 traditional European tomatoes (TRADITOM collection) and 2) a multipurpose core collection (TCC), comprising 227 European traditional tomato accessions from the original TRADITOM collection, that captured most of genotypic and phenotypic variation and geographical origin present in traditional tomato, Postprint (published version)

Published
2022

36. European traditional tomatoes galore: a result of farmers’ selection of a few diversity-rich loci

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Blanca, José, Pons, Clara, Montero Pau, Javier, Sanchez Matarredona, David, Ziarsolo, Pietro, Fontanet, Lilian, Fisher, Joseph, Plazas, Mariola, Casals Missio, Joan, Rambla, José Luis, Riccini, Alessandro, Pombarella, Samuela, Ruggiero, Alessandro, Sulli, MAria, Grillo, Stephania, Kanellis, Angelos, Giuliano, Giovani, Finkers, Richard, Cammareri, M, Grandillo, Silvana, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaume, Zamir, Dani, Cañizares, Joaquín, Monforte, Antonio, Granell, Antoni, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Blanca, José, Pons, Clara, Montero Pau, Javier, Sanchez Matarredona, David, Ziarsolo, Pietro, Fontanet, Lilian, Fisher, Joseph, Plazas, Mariola, Casals Missio, Joan, Rambla, José Luis, Riccini, Alessandro, Pombarella, Samuela, Ruggiero, Alessandro, Sulli, MAria, Grillo, Stephania, Kanellis, Angelos, Giuliano, Giovani, Finkers, Richard, Cammareri, M, Grandillo, Silvana, Mazzucato, Andrea, Causse, Mathilde, Díez, Maria José, Prohens, Jaume, Zamir, Dani, Cañizares, Joaquín, Monforte, Antonio, and Granell, Antoni

Abstract

A comprehensive collection of 1254 tomato accessions, corresponding to European traditional and modern varieties, early domesticated varieties, and wild relatives, was analyzed by genotyping by sequencing. A continuous genetic gradient between the traditional and modern varieties was observed. European traditional tomatoes displayed very low genetic diversity, with only 298 polymorphic loci (95% threshold) out of 64 943 total variants. European traditional tomatoes could be classified into several genetic groups. Two main clusters consisting of Spanish and Italian accessions showed higher genetic diversity than the remaining varieties, suggesting that these regions might be independent secondary centers of diversity with a different history. Other varieties seem to be the result of a more recent complex pattern of migrations and hybridizations among the European regions. Several polymorphic loci were associated in a genome-wide association study with fruit morphological traits in the European traditional collection. The corresponding alleles were found to contribute to the distinctive phenotypic characteristic of the genetic varietal groups. The few highly polymorphic loci associated with morphological traits in an otherwise a low-diversity population suggests a history of balancing selection, in which tomato farmers likely maintained the morphological variation by inadvertently applying a high selective pressure within different varietal types., This work was supported by the European Commission H2020 research and innovation program through TRADITOM grant agreement no. 634561, G2P-SOL, grant agreement no. 677379, and HARNESSTOM grant agreement no. 101000716. MP is grateful to the Spanish Ministerio de Ciencia e Innovación for a postdoctoral grant (IJC2019-039091-I/AEI/10.13039/501100011033)., Postprint (published version)

Published
2022

37. American and european tomato history unveiled using haplotype and GBS analyses

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Blanca, José, Montero Pau, Javier, Sanchez Matarredona, David, Ziarsolo, Pietro, Fontanet, Lilian, Riccini, Alessandro, Palombieri, Samuela, Mazzucato, Andrea, Grillo, Stephania, Kanellis, Angelos, Prohens, Jaume, Casals Missio, Joan, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Blanca, José, Montero Pau, Javier, Sanchez Matarredona, David, Ziarsolo, Pietro, Fontanet, Lilian, Riccini, Alessandro, Palombieri, Samuela, Mazzucato, Andrea, Grillo, Stephania, Kanellis, Angelos, Prohens, Jaume, and Casals Missio, Joan

Abstract

Not many historical or archeological records remain from the tomato journey from Solanum pimpinellifolium (SP) to the vintage varieties, however, its domestication, migrations and diversification in Europe can be unveiled using genetic analyses. The study of 628 SP, Solanum lycopersicum var. cerasiforme (SLC), and Solanum lycopersicum var. lycopersicum (SLL) revealed: 1) SP evolved into SLC during a migration from Peru and Ecuador, 2) there is a wild SLC Mesoamerican population, 3) there are no wild SLC populations in Ecuador and Peru, 4) Peruvian and Ecuadorian SLC are an admixture of Mesoamerican SLC and SP, 5) SP introgressions in SLC harbor flowering control and light response genes, 6) at least some Mesoamerican SLL derives from domesticated Peruvian and Ecuadorian SLC. A GBS analysis of 1,254 accessions, Postprint (published version)

Published
2022

38. Unlocking the European traditional tomato genetic resources

Author

Palombieri, Samuela, Fontanet, Lilian, Riccini, Alessandro, Rambla, José Luis, Ruggiero, Alessandro, Figàs, María del Rosario, Plazas, Mariola, Ziarsolo, Pietro, Casals Missio, Joan, Mazzucato, Andrea, Prohens, Jaume, and Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia

Subjects
Tomatoes, Tomàquets, Enginyeria agroalimentària::Agricultura::Horticultura [Àrees temàtiques de la UPC]
Abstract

The Mediterranean basin countries are considered secondary centres of tomato diversification. However, information on phenotypic and allelic variation of local tomato materials is still limited. To unveil the molecular basis of Southern European tomato phenotypic diversity, we carried out the most comprehensive phenotypic and genomic variability analysis on traditional European tomato by using 1) a collection of 1,499 traditional European tomatoes (TRADITOM collection) and 2) a multipurpose core collection (TCC), comprising 227 European traditional tomato accessions from the original TRADITOM collection, that captured most of genotypic and phenotypic variation and geographical origin present in traditional tomato

Published
2022

42. VKhUTEMAS 100. Progettare il museo di una Scuola per progettare il futuro

Author

Meriggi, Maurizio, Armando Dal Fabbro, and Raimonda, Riccini

Subjects
projects (part 3), Introduction to the volume that collects the materials of the IUAV Doctoral School seminar "VKhUTEMAS 100 - SPACE, Introduction to the volume that collects the materials of the IUAV Doctoral School seminar "VKhUTEMAS 100 - SPACE, PROJECT, TEACHING" - lessons (part 1), preliminary forms (part 2), projects (part 3), TEACHING" - lessons (part 1), PROJECT, preliminary forms (part 2)
Published
2022

46. American and european tomato history unveiled using haplotype and GBS analyses

Author

Blanca, José, Montero Pau, Javier, Sanchez Matarredona, David, Ziarsolo, Pietro, Fontanet, Lilian, Riccini, Alessandro, Palombieri, Samuela, Mazzucato, Andrea, Grillo, Stephania, Kanellis, Angelos, Prohens, Jaume, Casals Missio, Joan, and Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia

Subjects
Tomatoes, Tomàquets, Enginyeria agroalimentària::Agricultura::Horticultura [Àrees temàtiques de la UPC], Tomaquets
Abstract

Not many historical or archeological records remain from the tomato journey from Solanum pimpinellifolium (SP) to the vintage varieties, however, its domestication, migrations and diversification in Europe can be unveiled using genetic analyses. The study of 628 SP, Solanum lycopersicum var. cerasiforme (SLC), and Solanum lycopersicum var. lycopersicum (SLL) revealed: 1) SP evolved into SLC during a migration from Peru and Ecuador, 2) there is a wild SLC Mesoamerican population, 3) there are no wild SLC populations in Ecuador and Peru, 4) Peruvian and Ecuadorian SLC are an admixture of Mesoamerican SLC and SP, 5) SP introgressions in SLC harbor flowering control and light response genes, 6) at least some Mesoamerican SLL derives from domesticated Peruvian and Ecuadorian SLC. A GBS analysis of 1,254 accessions

Published
2022

48. Dai tariffari all'Open Source

Author

R. Riccini, M. Chiapponi, G. Ghidini, I. Austoni, A. Ubertazzi, M. Solaini, D. Sarti, B. Pasa, M. Romero, D. Beltramone, P. Costa, D. Piscitelli, A. Ramalho, E. lauro, G. M. Riccio, F. Rotolo, D. Nimmer, E. Derclaye, R. Caso, G. Dore, M. Sterpi, L. Savini, L. Biglia, A. Piai, AA.VV., B.Pasa, Riccini, R., Chiapponi, M., Ghidini, G., Austoni, I., Ubertazzi, A., Solaini, M., Sarti, D., Pasa, B., Romero, M., Beltramone, D., Costa, P., Piscitelli, D., Ramalho, A., Lauro, E., Riccio, G. M., Rotolo, F., Nimmer, D., Derclaye, E., Caso, R., Dore, G., Sterpi, M., Savini, L., Biglia, L., and Piai, A.

Subjects
Tariffari, guida agli onorari, aiap, copyright, copyleft,open patent, sharing
Abstract

Il testo intende costruire un sintetico scenario degli episodi più salienti legati alla tutela del progetto di comunicazione visiva - dai tariffari, alle associazioni professionali, al riconoscimento to della professione - per poter poi tracciare un possibile scenario delle questioni aperte dall’open source, dalla domesticizzazione della produzione degli artefatti, e dalle contemporanee pratiche di condivisione del lavoro. L’obiettivo non è quello di fornire soluzioni quanto piuttosto fare emergere un quadro da un lato storico (che possa includere anche il ruolo delle associazioni) e dall’altro lato tracciare questioni molto contemporanee, ancora aperte.

Published
2021

50. a

Author

Elimem, Mohamed, primary, Jaouadi, Rym, additional, Kalboussi, Maha, additional, Lahfef, Chaima, additional, Rouz, Slim, additional, Kharroubi, Hassan, additional, Boulila, Abdennacer, additional, Kouki, Sofien, additional, Ragnoni, Giuliano, additional, Pizzuti, Gianluca, additional, Primavera, Fabio, additional, Riccini, Alessandro, additional, and Cari, Alberto, additional

Published
2022
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