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264 results on '"Ricciardi, D."'

1. Differences in underlying cardiac substrate among S-ICD recipients and its impact on long-term device-related outcomes: Real-world insights from the iSUSI registry

Author

Gasperetti, A., Arosio, R., Viecca, M., Forleo, G.B., Schiavone, M., Tondo, C., Ziacchi, M., Diemberger, I., Angeletti, A., Biffi, M., Fierro, N., Gulletta, S., Della Bella, P., Curnis, G. Mitacchione.A., Compagnucci, P., Casella, M., Russo, A. Dello, Santini, L., Pignalberi, C., Magnocavallo, M., Piro, A., Lavalle, C., Picarelli, F., Ricciardi, D., Bressi, E., Calò, L., Montemerlo, E., Rovaris, G., De Bonis, S., Bisignani, A., Bisignani, G., Russo, G., Pisanò, E., Palmisano, P., Guarracini, F., Vitali, F., Bertini, M., Vogler, J., Fink, T., Tilz, R., Fastenrath, F., Kuschyk, J., Kaiser, L., Hakmi, S., Laredo, M., Waintraub, X., Gandjbakhch, E., Badenco, N., Breitenstein, A., Saguner, A.M., Martine, M., Seidl, S., Di Biase, L., Gasperetti, Alessio, Schiavone, Marco, Milstein, Jenna, Compagnucci, Paolo, Vogler, Julia, Laredo, Mikael, Breitenstein, Alexander, Gulletta, Simone, Martinek, Martin, Casella, Michela, Kaiser, Lukas, Santini, Luca, Rovaris, Giovanni, Curnis, Antonio, Biffi, Mauro, Kuschyk, Jürgen, Di Biase, Luigi, Tilz, Roland, Tondo, Claudio, and Forleo, Giovanni B.

Published
2024
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2. Impact of 2021 European Academy of Neurology/Peripheral Nerve Society diagnostic criteria on diagnosis and therapy of chronic inflammatory demyelinating polyradiculoneuropathy variants

Author

De&nbsp, Lorenzo, A, Liberatore, G, Doneddu, P, Manganelli, F, Cocito, D, Briani, C, Fazio, R, Mazzeo, A, Schenone, A, Di&nbsp, Stefano, V, Cosentino, G, Marfia, G, Benedetti, L, Carpo, M, Filosto, M, Antonini, G, Clerici, A, Luigetti, M, Matà, S, Rosso, T, Lucchetta, M, Siciliano, G, Lauria&nbsp, Pinter, G, Cavaletti, G, Inghilleri, M, Cantisani, T, Notturno, F, Ricciardi, D, Habetswallner, F, Spina, E, Peci, E, Salvalaggio, A, Falzone, Y, Strano, C, Gentile, L, Vegezzi, E, Mataluni, G, Cotti&nbsp, Piccinelli, S, Leonardi, L, Romano, A, Nobile-Orazio, E, Lorenzo A., Liberatore G., Doneddu P. E., Manganelli F., Cocito D., Briani C., Fazio R., Mazzeo A., Schenone A., Stefano V., Cosentino G., Marfia G. A., Benedetti L., Carpo M., Filosto M., Antonini G., Clerici A. M., Luigetti M., Matà S., Rosso T., Lucchetta M., Siciliano G., Pinter G., Cavaletti G., Inghilleri M., Cantisani T., Notturno F., Ricciardi D., Habetswallner F., Spina E., Peci E., Salvalaggio A., Falzone Y., Strano C., Gentile L., Vegezzi E., Mataluni G., Piccinelli S., Leonardi L., Romano A., Nobile-Orazio E., De&nbsp, Lorenzo, A, Liberatore, G, Doneddu, P, Manganelli, F, Cocito, D, Briani, C, Fazio, R, Mazzeo, A, Schenone, A, Di&nbsp, Stefano, V, Cosentino, G, Marfia, G, Benedetti, L, Carpo, M, Filosto, M, Antonini, G, Clerici, A, Luigetti, M, Matà, S, Rosso, T, Lucchetta, M, Siciliano, G, Lauria&nbsp, Pinter, G, Cavaletti, G, Inghilleri, M, Cantisani, T, Notturno, F, Ricciardi, D, Habetswallner, F, Spina, E, Peci, E, Salvalaggio, A, Falzone, Y, Strano, C, Gentile, L, Vegezzi, E, Mataluni, G, Cotti&nbsp, Piccinelli, S, Leonardi, L, Romano, A, Nobile-Orazio, E, Lorenzo A., Liberatore G., Doneddu P. E., Manganelli F., Cocito D., Briani C., Fazio R., Mazzeo A., Schenone A., Stefano V., Cosentino G., Marfia G. A., Benedetti L., Carpo M., Filosto M., Antonini G., Clerici A. M., Luigetti M., Matà S., Rosso T., Lucchetta M., Siciliano G., Pinter G., Cavaletti G., Inghilleri M., Cantisani T., Notturno F., Ricciardi D., Habetswallner F., Spina E., Peci E., Salvalaggio A., Falzone Y., Strano C., Gentile L., Vegezzi E., Mataluni G., Piccinelli S., Leonardi L., Romano A., and Nobile-Orazio E.

Abstract

Background and purpose: There are different criteria for the diagnosis of different variants of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). The 2021 European Academy of Neurology/Peripheral Nerve Society (EAN/PNS) guidelines provide specific clinical criteria for each CIDP variant even if their therapeutical impact has not been investigated. Methods: We applied the clinical criteria for CIDP variants of the 2021 EAN/PNS guidelines to 369 patients included in the Italian CIDP database who fulfilled the 2021 EAN/PNS electrodiagnostic criteria for CIDP. Results: According to the 2021 EAN/PNS clinical criteria, 245 patients achieved a clinical diagnosis of typical CIDP or CIDP variant (66%). We identified 106 patients with typical CIDP (29%), 62 distal CIDP (17%), 28 multifocal or focal CIDP (7%), four sensory CIDP (1%), 27 sensory-predominant CIDP (7%), 10 motor CIDP (3%), and eight motor-predominant CIDP (2%). Patients with multifocal, distal, and sensory CIDP had milder impairment and symptoms. Patients with multifocal CIDP had less frequently reduced conduction velocity and prolonged F-wave latency and had lower levels of cerebrospinal fluid protein. Patients with distal CIDP more frequently had reduced distal compound muscle action potentials. Patients with motor CIDP did not improve after steroid therapy, whereas those with motor-predominant CIDP did. None of the patients with sensory CIDP responded to steroids, whereas most of those with sensory-predominant CIDP did. Conclusions: The 2021 EAN/PNS criteria for CIDP allow a better characterization of CIDP variants, permitting their distinction from typical CIDP and more appropriate treatment for patients.

Published
2024

5. ECG screening and Sudden Cardiac Death prevention in endurance athletes

Author

Ricciardi, D, primary, Crispino, E, additional, Liporace, P, additional, Marchi, F, additional, Sanasi, L, additional, D'amore, M C, additional, Sposito, E, additional, Italiano, E L, additional, Loiacono, G, additional, Gioia, F, additional, Picarelli, F, additional, Calabrese, V, additional, Ussia, G P, additional, and Grigioni, F, additional

Published
2024
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6. Intermuscular technique for implantation of the subcutaneous implantable defibrillator: a propensity-matched case-control study

Author

Botto, G, Ziacchi, M, Nigro, G, D'Onofrio, A, Dello Russo, A, Francia, P, Viani, S, Pisano, E, Bisignani, G, Caravati, F, Migliore, F, De Filippo, P, Ottaviano, L, Rordorf, R, Manzo, M, Canevese, F, Lovecchio, M, Valsecchi, S, Checchi, L, Casale, M, Schintu, B, Scalone, A, Tola, G, Setzu, A, Curcio, A, Santoro, A, Baiocchi, C, Gentilini, R, Lunghetti, S, Solimene, F, Shopova, G, Schillaci, V, Arestia, A, Agresta, A, Bianchi, S, Rossi, P, Cauti, F, La Greca, C, Pecora, D, Ammirati, F, Santini, L, Mahfouz, K, Colaiaco, C, Vicentini, A, Savastano, S, Petracci, B, Sanzo, A, Baldi, E, Casula, M, Perego, G, Rella, V, Bianchi, V, Tavoletta, V, De Vivo, S, Palmisano, P, Accogli, M, Milanese, G, Pepi, P, Nicolis, D, Mariani, M, Pagani, M, Bonfantino, M, Caccavo, V, Grimaldi, M, Katsouras, G, Forleo, G, Chieffo, E, Tavarelli, E, Brambilla, R, Pani, A, Giammaria, M, Lucciola, M, Amellone, C, Uran, C, Baroni, M, Ferrari, P, Leidi, C, Drago, F, Silvetti, M, Pazzano, V, Russo, S, Remoli, R, Battipaglia, I, Cazzoli, I, Saputo, F, Devecchi, C, Barbonaglia, L, Viscusi, M, Brignoli, M, Mattera, A, Pedretti, S, Lupi, A, Tommasi, S, Kol, A, Gatto, M, Persi, A, Gonella, A, Rossetti, G, Menardi, E, Rossini, R, Notarstefano, P, Nesti, M, Fraticelli, A, Carreras, G, Donzelli, S, Marini, C, Tordini, A, Lazzari, L, Sartori, P, Di Donna, P, Mascia, G, Capogrosso, P, Magliano, P, Colimodio, M, Sala, S, Mazzone, P, Della Bella, P, Coppolino, A, Arena, G, Borrello, V, Ratti, M, Bartoli, C, Palano, F, Adduci, C, Torriglia, A, Laffi, M, Esposito, C, Giano, A, Franculli, F, Pangallo, A, De Bonis, S, Sarubbi, B, Colonna, D, Correra, A, Romeo, E, Rapacciuolo, A, Liguori, V, Viggiano, A, Strisciullo, T, Biffi, M, Diemberger, I, Martignani, C, Piro, A, Lavalle, C, Magnocavallo, M, Ricciardi, D, Calabrese, V, Gioia, F, Picarelli, F, Licciardello, G, Busacca, G, Calvi, V, Lamberti, F, Lumia, G, Bellini, C, Bianchi, C, Savarese, G, Andreoli, C, Pimpinicchio, L, Pellegrini, D, Giorgi, D, Bovenzi, Busoni, F, Daleffe, E, Facchin, D, Rebellato, L, Stifano, G, Magliano, G, Sergi, D, Barone, L, Morgagni, R, Casella, M, Guerra, F, Cipolletta, L, Molini, S, De Lucia, R, Di Cori, A, Grifoni, G, Paperini, L, Segreti, L, Soldati, E, Zucchelli, G, Russo, V, Rago, A, Ammendola, E, Papa, A, Pieragnoli, P, Ricciardi, G, Perrotta, L, Botto G. L., Ziacchi M., Nigro G., D'Onofrio A., Dello Russo A., Francia P., Viani S., Pisano E., Bisignani G., Caravati F., Migliore F., De Filippo P., Ottaviano L., Rordorf R., Manzo M., Canevese F. L., Lovecchio M., Valsecchi S., Checchi L., Casale M. C., Schintu B., Scalone A., Tola G., Setzu A., Curcio A., Santoro A., Baiocchi C., Gentilini R., Lunghetti S., Solimene F., Shopova G., Schillaci V., Arestia A., Agresta A., Bianchi S., Rossi P., Cauti F. M., La Greca C., Pecora D., Ammirati F., Santini L., Mahfouz K., Colaiaco C., Vicentini A., Savastano S., Petracci B., Sanzo A., Baldi E., Casula M., Perego G. B., Rella V., Bianchi V., Tavoletta V., De Vivo S., Palmisano P., Accogli M., Milanese G., Pepi P., Nicolis D., Mariani M., Pagani M., Bonfantino M. V., Caccavo V., Grimaldi M., Katsouras G., Forleo G. B., Chieffo E., Tavarelli E., Brambilla R., Pani A., Giammaria M., Lucciola M. T., Amellone C., Uran C., Baroni M., Ferrari P., Leidi C., Drago F., Silvetti M. S., Pazzano V., Russo S., Remoli R., Battipaglia I., Cazzoli I., Saputo F., Devecchi C., Barbonaglia L., Viscusi M., Brignoli M., Mattera A., Pedretti S., Lupi A., Tommasi S., Kol A., Gatto M. C., Persi A., Gonella A., Rossetti G., Menardi E., Rossini R., Notarstefano P., Nesti M., Fraticelli A., Carreras G., Donzelli S., Marini C., Tordini A., Lazzari L., Sartori P., Di Donna P., Mascia G., Capogrosso P., Magliano P., Colimodio M., Sala S., Mazzone P., Della Bella P., Coppolino A., Arena G., Borrello V., Ratti M., Bartoli C., Palano F., Adduci C., Torriglia A., Laffi M., Esposito C., Giano A., Franculli F., Pangallo A., De Bonis S., Sarubbi B., Colonna D., Correra A., Romeo E., Rapacciuolo A., Liguori V., Viggiano A., Strisciullo T., Biffi M., Diemberger I., Martignani C., Piro A., Lavalle C., Magnocavallo M., Mariani M. V., Ricciardi D., Calabrese V., Gioia F., Picarelli F., Licciardello G., Busacca G., Calvi V. I., Lamberti F., Lumia G., Bellini C., Bianchi C., Savarese G., Andreoli C., Pimpinicchio L., Pellegrini D., Giorgi D., Busoni F., Daleffe E., Facchin D., Rebellato L., Stifano G., Magliano G., Sergi D., Barone L., Morgagni R., Casella M., Guerra F., Cipolletta L., Molini S., De Lucia R., Di Cori A., Grifoni G., Paperini L., Segreti L., Soldati E., Zucchelli G., Russo V., Rago A., Ammendola E., Papa A., Pieragnoli P., Ricciardi G., Perrotta L., Botto, G, Ziacchi, M, Nigro, G, D'Onofrio, A, Dello Russo, A, Francia, P, Viani, S, Pisano, E, Bisignani, G, Caravati, F, Migliore, F, De Filippo, P, Ottaviano, L, Rordorf, R, Manzo, M, Canevese, F, Lovecchio, M, Valsecchi, S, Checchi, L, Casale, M, Schintu, B, Scalone, A, Tola, G, Setzu, A, Curcio, A, Santoro, A, Baiocchi, C, Gentilini, R, Lunghetti, S, Solimene, F, Shopova, G, Schillaci, V, Arestia, A, Agresta, A, Bianchi, S, Rossi, P, Cauti, F, La Greca, C, Pecora, D, Ammirati, F, Santini, L, Mahfouz, K, Colaiaco, C, Vicentini, A, Savastano, S, Petracci, B, Sanzo, A, Baldi, E, Casula, M, Perego, G, Rella, V, Bianchi, V, Tavoletta, V, De Vivo, S, Palmisano, P, Accogli, M, Milanese, G, Pepi, P, Nicolis, D, Mariani, M, Pagani, M, Bonfantino, M, Caccavo, V, Grimaldi, M, Katsouras, G, Forleo, G, Chieffo, E, Tavarelli, E, Brambilla, R, Pani, A, Giammaria, M, Lucciola, M, Amellone, C, Uran, C, Baroni, M, Ferrari, P, Leidi, C, Drago, F, Silvetti, M, Pazzano, V, Russo, S, Remoli, R, Battipaglia, I, Cazzoli, I, Saputo, F, Devecchi, C, Barbonaglia, L, Viscusi, M, Brignoli, M, Mattera, A, Pedretti, S, Lupi, A, Tommasi, S, Kol, A, Gatto, M, Persi, A, Gonella, A, Rossetti, G, Menardi, E, Rossini, R, Notarstefano, P, Nesti, M, Fraticelli, A, Carreras, G, Donzelli, S, Marini, C, Tordini, A, Lazzari, L, Sartori, P, Di Donna, P, Mascia, G, Capogrosso, P, Magliano, P, Colimodio, M, Sala, S, Mazzone, P, Della Bella, P, Coppolino, A, Arena, G, Borrello, V, Ratti, M, Bartoli, C, Palano, F, Adduci, C, Torriglia, A, Laffi, M, Esposito, C, Giano, A, Franculli, F, Pangallo, A, De Bonis, S, Sarubbi, B, Colonna, D, Correra, A, Romeo, E, Rapacciuolo, A, Liguori, V, Viggiano, A, Strisciullo, T, Biffi, M, Diemberger, I, Martignani, C, Piro, A, Lavalle, C, Magnocavallo, M, Ricciardi, D, Calabrese, V, Gioia, F, Picarelli, F, Licciardello, G, Busacca, G, Calvi, V, Lamberti, F, Lumia, G, Bellini, C, Bianchi, C, Savarese, G, Andreoli, C, Pimpinicchio, L, Pellegrini, D, Giorgi, D, Bovenzi, Busoni, F, Daleffe, E, Facchin, D, Rebellato, L, Stifano, G, Magliano, G, Sergi, D, Barone, L, Morgagni, R, Casella, M, Guerra, F, Cipolletta, L, Molini, S, De Lucia, R, Di Cori, A, Grifoni, G, Paperini, L, Segreti, L, Soldati, E, Zucchelli, G, Russo, V, Rago, A, Ammendola, E, Papa, A, Pieragnoli, P, Ricciardi, G, Perrotta, L, Botto G. L., Ziacchi M., Nigro G., D'Onofrio A., Dello Russo A., Francia P., Viani S., Pisano E., Bisignani G., Caravati F., Migliore F., De Filippo P., Ottaviano L., Rordorf R., Manzo M., Canevese F. L., Lovecchio M., Valsecchi S., Checchi L., Casale M. C., Schintu B., Scalone A., Tola G., Setzu A., Curcio A., Santoro A., Baiocchi C., Gentilini R., Lunghetti S., Solimene F., Shopova G., Schillaci V., Arestia A., Agresta A., Bianchi S., Rossi P., Cauti F. M., La Greca C., Pecora D., Ammirati F., Santini L., Mahfouz K., Colaiaco C., Vicentini A., Savastano S., Petracci B., Sanzo A., Baldi E., Casula M., Perego G. B., Rella V., Bianchi V., Tavoletta V., De Vivo S., Palmisano P., Accogli M., Milanese G., Pepi P., Nicolis D., Mariani M., Pagani M., Bonfantino M. V., Caccavo V., Grimaldi M., Katsouras G., Forleo G. B., Chieffo E., Tavarelli E., Brambilla R., Pani A., Giammaria M., Lucciola M. T., Amellone C., Uran C., Baroni M., Ferrari P., Leidi C., Drago F., Silvetti M. S., Pazzano V., Russo S., Remoli R., Battipaglia I., Cazzoli I., Saputo F., Devecchi C., Barbonaglia L., Viscusi M., Brignoli M., Mattera A., Pedretti S., Lupi A., Tommasi S., Kol A., Gatto M. C., Persi A., Gonella A., Rossetti G., Menardi E., Rossini R., Notarstefano P., Nesti M., Fraticelli A., Carreras G., Donzelli S., Marini C., Tordini A., Lazzari L., Sartori P., Di Donna P., Mascia G., Capogrosso P., Magliano P., Colimodio M., Sala S., Mazzone P., Della Bella P., Coppolino A., Arena G., Borrello V., Ratti M., Bartoli C., Palano F., Adduci C., Torriglia A., Laffi M., Esposito C., Giano A., Franculli F., Pangallo A., De Bonis S., Sarubbi B., Colonna D., Correra A., Romeo E., Rapacciuolo A., Liguori V., Viggiano A., Strisciullo T., Biffi M., Diemberger I., Martignani C., Piro A., Lavalle C., Magnocavallo M., Mariani M. V., Ricciardi D., Calabrese V., Gioia F., Picarelli F., Licciardello G., Busacca G., Calvi V. I., Lamberti F., Lumia G., Bellini C., Bianchi C., Savarese G., Andreoli C., Pimpinicchio L., Pellegrini D., Giorgi D., Busoni F., Daleffe E., Facchin D., Rebellato L., Stifano G., Magliano G., Sergi D., Barone L., Morgagni R., Casella M., Guerra F., Cipolletta L., Molini S., De Lucia R., Di Cori A., Grifoni G., Paperini L., Segreti L., Soldati E., Zucchelli G., Russo V., Rago A., Ammendola E., Papa A., Pieragnoli P., Ricciardi G., and Perrotta L.

Abstract

Aims A previous randomized study demonstrated that the subcutaneous implantable cardioverter defibrillator (S-ICD) was noninferior to transvenous ICD with respect to device-related complications and inappropriate shocks. However, that was performed prior to the widespread adoption of pulse generator implantation in the intermuscular (IM) space instead of the traditional subcutaneous (SC) pocket. The aim of this analysis was to compare survival from device-related complications and inappropriate shocks between patients who underwent S-ICD implantation with the generator positioned in an IM position in comparison with an SC pocket. Methods and results We analysed 1577 consecutive patients who had undergone S-ICD implantation from 2013 to 2021 and were followed up until December 2021. Subcutaneous patients (n = 290) were propensity matched with patients of the IM group (n = 290), and their outcomes were compared. : During a median follow-up of 28 months, device-related complications were reported in 28 (4.8%) patients and inappropriate shocks were reported in 37 (6.4%) patients. The risk of complication was lower in the matched IM group than in the SC group [hazard ratio 0.41, 95% confidence interval (CI) 0.17-0.99, P = 0.041], as well as the composite of complications and inappropriate shocks (hazard ratio 0.50, 95% CI 0.30-0.86, P = 0.013). The risk of appropriate shocks was similar between groups (hazard ratio 0.90, 95% CI 0.50-1.61, P = 0.721). There was no significant interaction between generator positioning and variables such as gender, age, body mass index, and ejection fraction. Conclusion Our data showed the superiority of the IM S-ICD generator positioning in reducing device-related complications and inappropriate shocks.

Published
2023

8. Inappropriate Shock Rates and Long-Term Complications due to Subcutaneous Implantable Cardioverter Defibrillators in Patients With and Without Heart Failure: Results From a Multicenter, International Registry

Author

Schiavone, Marco, primary, Gasperetti, Alessio, additional, Laredo, Mikael, additional, Breitenstein, Alexander, additional, Vogler, Julia, additional, Palmisano, Pietro, additional, Gulletta, Simone, additional, Pignalberi, Carlo, additional, Lavalle, Carlo, additional, Pisanò, Ennio, additional, Ricciardi, Danilo, additional, Curnis, Antonio, additional, Dello Russo, Antonio, additional, Tondo, Claudio, additional, Badenco, Nicolas, additional, Di Biase, Luigi, additional, Kuschyk, Jürgen, additional, Biffi, Mauro, additional, Tilz, Roland, additional, Forleo, Giovanni Battista, additional, Schiavone, M., additional, Gasperetti, A., additional, Arosio, R., additional, Ruggiero, D., additional, Viecca, M., additional, Forleo, G.B., additional, Ziacchi, M., additional, Diemberger, I., additional, Angeletti, A., additional, Biffi, M., additional, Fierro, N., additional, Gulletta, S., additional, Della Bella, P., additional, Tondo, C., additional, Mitacchione, G., additional, Curnis, A., additional, Compagnucci, P., additional, Casella, M., additional, Dello Russo, A., additional, Santini, L., additional, Pignalberi, C., additional, Piro, A., additional, Lavalle, C., additional, Picarelli, F., additional, Ricciardi, D., additional, Bressi, E., additional, Calò, L., additional, Montemerlo, E., additional, Rovaris, G., additional, De Bonis, S., additional, Bisignani, A., additional, Bisignani, G., additional, Russo, G., additional, Pisanò, E., additional, Palmisano, P., additional, Guarracini, F., additional, Vitali, F., additional, Bertini, M., additional, Vogler, J., additional, Fink, T., additional, Tilz, R., additional, Fastenrath, F., additional, Kuschyk, J., additional, Kaiser, L., additional, Hakmi, S., additional, Laredo, M., additional, Waintraub, X, additional, Gandjbakhch, E., additional, Badenco, N., additional, Breitenstein, A., additional, Saguner, A.M., additional, and Di Biase, L., additional

Published
2023
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12. The subcutaneous defibrillator in patients with low BMI - insights from a large European multicenter registry

Author

Vogler, J, primary, Gasperetti, A, additional, Schiavone, M, additional, Breitenstein, A, additional, Laredo, M, additional, Palmisano, P, additional, Mitacchione, G, additional, Hakmi, S, additional, Ricciardi, D, additional, Arosio, R, additional, Casella, M, additional, Kuschyk, J, additional, Biffi, M, additional, Forleo, GB, additional, and Tilz, RR, additional

Published
2022
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13. P25 SUBCUTANEOUS–ICD IN PATIENTS WITH HEART FAILURE: RESULTS FROM A MULTICENTER, EUROPEAN ANALYSIS

Author

Schiavone, M, primary, Gasperetti, A, additional, Mitacchione, G, additional, Angeletti, A, additional, Vogler, J, additional, Laredo, M, additional, Breitenstein, A, additional, Gulletta, S, additional, Fastenrath, F, additional, Kaiser, L, additional, Compagnucci, P, additional, Palmisano, P, additional, Ricciardi, D, additional, Santini, L, additional, De Bonis, S, additional, Piro, A, additional, Pignalberi, C, additional, Pisanò, E, additional, Hakmi, S, additional, Arosio, R, additional, Casella, M, additional, Lavalle, C, additional, Badenco, N, additional, Della Bella, P, additional, Dello Russo, A, additional, Curnis, A, additional, Tondo, C, additional, Steffel, J, additional, Viecca, M, additional, Kuschyk, J, additional, Tilz, R, additional, Biffi, M, additional, and Forleo, G, additional

Published
2022
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14. P21 AGE–RELATED DIFFERENCES AND ASSOCIATED OUTCOMES OF S–ICD: INSIGHTS FROM A LARGE, EUROPEAN, MULTICENTER REGISTRY

Author

Schiavone, M, primary, Gasperetti, A, additional, Gulletta, S, additional, Vogler, J, additional, Fastenrath, F, additional, Breitenstein, A, additional, Laredo, M, additional, Mitacchione, G, additional, Palmisano, P, additional, Compagnucci, P, additional, Kaiser, L, additional, Denora, M, additional, Hakmi, S, additional, Angeletti, A, additional, De Bonis, S, additional, Picarelli, F, additional, Casella, M, additional, Steffel, J, additional, Ferro, N, additional, Guarracini, F, additional, Santini, L, additional, Pignalberi, C, additional, Piro, A, additional, Lavalle, C, additional, Russo, G, additional, Pisanò, E, additional, Viecca, M, additional, Curnis, A, additional, Badenco, N, additional, Ricciardi, D, additional, Dello Russo, A, additional, Tondo, C, additional, Kuschyk, J, additional, Della Bella, P, additional, Biffi, M, additional, Tilz, R, additional, and Forleo, G, additional

Published
2022
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15. C9 SUBCUTANEOUS IMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN PATIENTS WITH LOW BMI: REAL–WORLD DATA FROM A EUROPEAN MULTICENTER ANALYSIS

Author

Schiavone, M, primary, Gasperetti, A, additional, Vogler, J, additional, Mitacchione, G, additional, Gulletta, S, additional, Palmisano, P, additional, Breitenstein, A, additional, Laredo, M, additional, Compagnucci, P, additional, Angeletti, A, additional, Kaiser, L, additional, Hakmi, S, additional, Russo, G, additional, Ricciardi, D, additional, De Bonis, S, additional, Arosio, R, additional, Casella, M, additional, Santini, L, additional, Pignalberi, C, additional, Piro, A, additional, Lavalle, C, additional, Pisanò, E, additional, Denora, M, additional, Viecca, M, additional, Curnis, A, additional, Badenco, N, additional, Dello Russo, A, additional, Tondo, C, additional, Kuschyk, J, additional, Della Bella, P, additional, Tilz, R, additional, Biffi, M, additional, and Forleo, G, additional

Published
2022
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17. Five waves of COVID-19 pandemic in Italy: results of a national survey evaluating the impact on activities related to arrhythmias, pacing, and electrophysiology promoted by AIAC (Italian Association of Arrhythmology and Cardiac Pacing)

Author

Boriani, G., Guerra, F., De Ponti, R., D'Onofrio, A., Accogli, M., Bertini, M., Bisignani, G., Forleo, G. B., Landolina, M., Lavalle, C., Notarstefano, P., Ricci, R. P., Zanotto, G., Palmisano, P., Luise, R., De Bonis, S., Pangallo, A., Talarico, A., Maglia, G., Aspromonte, V., Nigro, G., Bianchi, V., Rapacciuolo, A., Ammendola, E., Solimene, F., Stabile, G., Biffi, M., Ziacchi, M., Malpighi, P. S. O., Saporito, D., Casali, E., Turco, V., Malavasi, V. L., Vitolo, M., Imberti, J. F., Anna, A. S., Zardini, M., Placci, A., Quartieri, F., Bottoni, N., Carinci, V., Barbato, G., De Maria, E., Borghi, A., Ramazzini, O. B., Bronzetti, G., Tomasi, C., Boggian, G., Virzi, S., Sassone, B., Corzani, A., Sabbatani, P., Pastori, P., Ciccaglioni, A., Adamo, F., Scaccia, A., Spampinato, A., Patruno, N., Biscione, F., Cinti, C., Pignalberi, C., Calo, L., Tancredi, M., Di Belardino, N., Ricciardi, D., Cauti, F., Rossi, P., Cardinale, M., Ansalone, G., Narducci, M. L., Pelargonio, G., Silvetti, M., Drago, F., Santini, L., Pentimalli, F., Pepi, P., Caravati, F., Taravelli, E., Belotti, G., Rordorf, R., Mazzone, P., Bella, P. D., Rossi, S., Canevese, L. F., Cilloni, S., Doni, L. A., Vergara, P., Baroni, M., Perna, E., Gardini, A., Negro, R., Perego, G. B., Curnis, A., Arabia, G., Russo, A. D., Marchese, P., Dell'Era, G., Occhetta, E., Pizzetti, F., Amellone, C., Giammaria, M., Devecchi, C., Coppolino, A., Tommasi, S., Anselmino, M., Coluccia, G., Guido, A., Rillo, M., Palama, Z., Luzzi, G., Pellegrino, P. L., Grimaldi, M., Grandinetti, G., Vilei, E., Potenza, D., Scicchitano, P., Favale, S., Santobuono, V. E., Sai, R., Melissano, D., Candida, T. R., Bonfantino, V. M., Di Canda, D., Gianfrancesco, D., Carretta, D., Pisano, E. C. L., Medico, A., Giaccari, R., Aste, R., Murgia, C., Nissardi, V., Sanna, G. D., Firetto, G., Crea, P., Ciotta, E., Sgarito, G., Caramanno, G., Ciaramitaro, G., Faraci, A., Fasheri, A., Di Gregorio, L., Campsi, G., Muscio, G., Giannola, G., Padeletti, M., Del Rosso, A., Nesti, M., Miracapillo, G., Giovannini, T., Pieragnoli, P., Rauhe, W., Marini, M., Guarracini, F., Ridarelli, M., Fedeli, F., Mazza, A., Zingarini, G., Andreoli, C., Carreras, G., Zorzi, A., Rossillo, A., Ignatuk, B., Zerbo, F., Molon, G., Fantinel, M., Zanon, F., Marcantoni, L., Zadro, M., and Bevilacqua, M.

Subjects
Cardiac resynchronization therapy, Remote monitoring, Emergency Medicine, Internal Medicine, Ablation, Arrhythmia, Atrial fibrillation, COVID-19, Implantable cardioverter defibrillators, Pacemakers
Abstract

The subsequent waves of the COVID-19 pandemic in Italy had a major impact on cardiac care.A survey to evaluate the dynamic changes in arrhythmia care during the first five waves of COVID-19 in Italy (first: March-May 2020; second: October 2020-January 2021; third: February-May 2021; fourth: June-October 2021; fifth: November 2021-February 2022) was launched.A total of 127 physicians from arrhythmia centers (34% of Italian centers) took part in the survey. As compared to 2019, a reduction in 40% of elective pacemaker (PM), defibrillators (ICD), and cardiac resynchronization devices (CRT) implantations, with a 70% reduction for ablations, was reported during the first wave, with a progressive and gradual return to pre-pandemic volumes, generally during the third-fourth waves, slower for ablations. For emergency procedures (PM, ICD, CRT, and ablations), recovery from the initial 10% decline occurred in most cases during the second wave, with some variability. However, acute care for atrial fibrillation, electrical cardioversions, and evaluations for syncope showed a prolonged reduction of activity. The number of patients with devices which started remote monitoring increased by 40% during the first wave, but then the adoption of remote monitoring declined.The dramatic and profound derangement in arrhythmia management that characterized the first wave of the COVID-19 pandemic was followed by a progressive return to the volume of activities of the pre-pandemic periods, even if with different temporal dynamics and some heterogeneity. Remote monitoring was largely implemented during the first wave, but full implementation is needed.

Published
2022

18. The need for a subsequent transvenous system in patiets implanted with subcutaneous implantable cardioverter defibrillator

Author

Gasperetti, A, Schiavone, M, Vogler, J, Laredo, M, Fastenrath, P, Ziacchi, M, Angeletti, A, Mitacchione, G, Kaiser, I, Breitenstein A, Compamcci P., Arpsi, L, Vitali, F, De Bonis, S, Picarelli, F, Casella, M, Santini, M, Pignalberti, C, Lavalle, C, Pisan, E, Ricciardi, D, Calò, L, Curnis, A, Bertini, M, Dello Russo A, Gulletta S., Baden, N, Tondo, C, Kuschyk, J, Tilz, R, Forleo, Gb, and Biffi, M

Published
2022

19. Establishing the Injury Severity of Subaxial Cervical Spine Trauma: Validating the Hierarchical Nature of the AO Spine Subaxial Cervical Spine Injury Classification System

Author

Schroeder, G. D., Canseco, J. A., Patel, P. D., Divi, S. N., Karamian, B. A., Kandziora, F., Vialle, E. N., Oner, F. C., Schnake, K. J., Dvorak, M. F., Chapman, J. R., Benneker, L. M., Rajasekaran, S., Kepler, C. K., Vaccaro, A. R., Abdelgawaad, A. S., Abdul, W., Abdulsalam, A., Abeid, M., Ackshota, N., Acosta, O., Akman, Y., Aldahamsheh, O., Alhammoud, A., Aleixo, H., Alexander, H., Alkharsawi, M., Alsammak, W., Amadou, H., Amin, M., Arbatin, J., Atan, A., Athanasiou, A., Bas, P., Bazan, P., Benzakour, T., Benzarti, S., Bernucci, C., Bosco, A., Butler, J., Castillo, A., Cawley, D., Chek, W., Chen, J., Cheng, C., Cheung, J., Chong, C., Corluka, S., Corredor, J., Costa, B., Curri, C., Dawoud, A., Delgado-Fernandez, J., Demiroz, S., Desai, A., Diez-Ulloa, M., Dimas, N., Diniz, S., Direito-Santos, B., Duerinck, J., El-Hewala, T., El-Shamly, M., El-Sharkawi, M., Espinosa, G., Estefan, M., Fang, T., Fernandes, M., Fernandez, N., Ferreira, M., Figueiredo, A., Fiorenza, V., Francis, J., Franz, S., Freedman, B., Fu, L., Fuego, S., Gahlot, N., Ganau, M., Garcia-Pallero, M., Garg, B., Gidvani, S., Giera, B., Godinho, A., Goni, M., Gonzalez, M., Gonzalez, R., Gopalakrishnan, D., Grin, A., Grozman, S., Gruenberg, M., Grundshtein, A., Guasque, J., Guerra, O., Guiroy, A., Hackla, S., Harris, C., Harrop, J., Hassan, W., Henine, A., Hickman, Z., Igualada, C., James, A., Jetjumnong, C., Kaen, A., Karmacharya, B., Kilincer, C., Klezl, Z., Koerner, J., Konrads, C., Krappel, F., Kruyt, M., Krywinski, F., Kundangar, R., Landriel, F., Lindtner, R., Linhares, D., Llombart-Blanco, R., Lopez, W., Lotan, R., Lourido, J., Luna, L., Magashi, T., Majer, C., Mandizvidza, V., Manilha, R., Mannara, F., Margetis, K., Medina, F., Milano, J., Miyakoshi, N., Moisa, H., Montemurro, N., Montoya, J., Morais, J., Morande, S., Msuya, S., Mubarak, M., Mulbah, R., Murugan, Y., Nacer, M., Neves, N., Nicassio, N., Niemeier, T., Olorunsogo, M., Orosco, D., Ozdener, K., Paez, R., Panchal, R., Paterakis, K., Pemovska, E., Pereira, P., Perovic, D., Perozo, J., Pershin, A., Phedy, P., Picazo, D., Pitti, F., Platz, U., Pluderi, M., Ponnusamy, G., Popescu, E., Ramakrishnan, S., Ramieri, A., Rebholz, B., Ricciardi, G., Ricciardi, D., Robinson, Y., Rodriguez, L., Rodrigues-Pinto, R., Romero, I., Rosas, R., Russo, S., Rutges, J., Sartor, F., Shariati, B., Sharma, J., Shoaib, M., Smith, S., Sorimachi, Y., Sribastav, S., Steiner, C., Subbiah, J., Subramanian, P., Suri, T., Tannoury, C., Tokala, D., Toluse, A., Ungurean, V., Vahl, J., Valacco, M., Valdez, C., Vernengo-Lezica, A., Veroni, A., Vieira, R., Viswanadha, A., Wagner, S., Wamae, D., Weening, A., Weidert, S., W. -T., Wu, M. -H., Wu, Yuan, H., Yuh, S. -J., Yurac, R., Zarate-Kalfopulos, B., Ziabrov, A., Zubairi, A., Surgical clinical sciences, Neuroprotection & Neuromodulation, and Neurosurgery

Subjects
Adult, Male, Facet (geometry), medicine.medical_specialty, Cross-sectional study, Clinical Neurology, 610 Medicine & health, Cervical spine injury, cervical spine, Severity of Illness Index, 03 medical and health sciences, 0302 clinical medicine, Injury Severity Score, Surveys and Questionnaires, Severity of illness, Validation, medicine, Humans, Orthopedics and Sports Medicine, Spinal cord injury, Spinal Cord Injuries, 030222 orthopedics, business.industry, Reproducibility of Results, AO spine subaxial cervical spine injury, Cervical spine, Classification system, Injury severity score, Trauma, Cervical Vertebrae, Cross-Sectional Studies, Female, medicine.disease, medicine.anatomical_structure, trauma, Neurology (clinical), Radiology, business, 030217 neurology & neurosurgery, Cervical vertebrae
Abstract

STUDY DESIGN Global cross-sectional survey. OBJECTIVE To validate the AO Spine Subaxial Cervical Spine Injury Classification by examining the perceived injury severity by surgeon across AO geographical regions and practice experience. SUMMARY OF BACKGROUND DATA Previous subaxial cervical spine injury classifications have been limited by subpar interobserver reliability and clinical applicability. In an attempt to create a universally validated scheme with prognostic value, AO Spine established a subaxial cervical spine injury classification involving four elements: (1) injury morphology, (2) facet injury involvement, (3) neurologic status, and (4) case-specific modifiers. METHODS A survey was sent to 272 AO Spine members across all geographic regions and with a variety of practice experience. Respondents graded the severity of each variable of the classification system on a scale from zero (low severity) to 100 (high severity). Primary outcome was to assess differences in perceived injury severity for each injury type over geographic regions and level of practice experience. RESULTS A total of 189 responses were received. Overall, the classification system exhibited a hierarchical progression in subtype injury severity scores. Only three subtypes showed a significant difference in injury severity score among geographic regions: F3 (floating lateral mass fracture, p:0.04), N3 (incomplete spinal cord injury, p:0.03), and M2 (critical disk herniation, p:0.04). When stratified by surgeon experience, pairwise comparison showed only 2 morphological subtypes, B1 (bony posterior tension band injury, p:0.02) and F2 (unstable facet fracture, p:0.03), and one neurologic subtype (N3, p:0.02) exhibited a significant difference in injury severity score. CONCLUSIONS The AO Spine Subaxial Cervical Spine Injury Classification System has shown to be reliable and suitable for proper patient management. The study shows this classification is substantially generalizable by geographic region and surgeon experience; and provides a consistent method of communication among physicians while covering the majority of subaxial cervical spine traumatic injuries.Level of Evidence: 4.

Published
2021
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23. Subcutaneous implantable cardioveryter/defibrillation testing,A propensity-matched pilot study

Author

Forleo, Gb, Gasperetti, A, Breitenstein, A, Laredo, M, Schiavone, M, Ziacchi, M, Vogler, J, Ricciardi, D, Palmisano, P, Piro, A, Compagnucci, P, Waintrub, X, Mitacchione, G, Carrassa, G, Russo, G, De Bonis, S, Angeletti, A, Bisignani, A, Picarelli, F, Casella, M, Bressi, E, Rovaris, G, P L, Calòp, Santini, L, Pignalberi, C, Lavalle, C, Viecca, M, Pisanò, E, Olivotto, I, Curnis, A, Dello Russo, A, Tondo, C, Love, Cj, Di Biase, L, Steffel, J, Tilz, R, Badenco, N, and Biffi, M

Published
2021

24. Subcutaneos implantable cardioverter defibrillator and defibrillation testing: a propensity-matched pilot study

Author

Forleo, Gb, Gasperetti, A, Breitenstein, A, Laredo, M, Schiavone, M, Ziacchi, M, Vogler, J, Ricciardi, D, Palmisano, P., Piro, A, Compagnucci, P, Waintraub, X, Mitacchioneg, Carassa, G, Russo, G, Bonis, S, Anagelettia, Bisignani, A, Picarelli, F, Bressine, Rovaris, G, Calò, L, Santini, L, Pignalberi, C, Lavalle, C, Pisanò, E, Olivotto, I, Curnis, A, Russo, Ad, Tondo, C, Loce, Cj, Biase, Ld, Steffel<, J, Tilz, R, Badensìco, N, and Biffi, M

Published
2021

25. Long term complications in patients implanted with subcutaneous implantable defibrillators real-world data from the Extended ELISIR experience

Author

Gasperetti, A, Schiavone, M, Ziacchi, M, Vogler, J, Breitenstein, A, Laredo, M, Palmisano, P, Ricciardi, D, Mitacchione, F, Compagnucci, P, Bisignani, A, Angeletti, A, Casella, M, Picarelli, F, Fink, T, Kaiser, L, Hakmi, S, Calò, L, Pignalberi, C, Santini, L. ì., Lavalle, C, Pisanòe, Olivotto, I, Tondo, C, Curnis, A, Russo, Ad, Badenco, N, Steffeli, J, Love, Cj, Tilz, R, Forleo, G, and Biffi, M.

Published
2021

27. Parkinson’s disease and virtual reality rehabilitation: cognitive reserve influences the walking and balance outcome

Author

Imbimbo, Isabella, Coraci, Daniele, Santilli, C., Loreti, Claudia, Piccinini, Giulia, Ricciardi, Diego, Castelli, Letizia, Fusco, Augusto, Bentivoglio, Anna Rita, Padua, Luca, Imbimbo I., Coraci D., Loreti C., Piccinini G., Ricciardi D., Castelli L. (ORCID:0000-0001-9455-3789), Fusco A., Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Padua L. (ORCID:0000-0003-2570-9326), Imbimbo, Isabella, Coraci, Daniele, Santilli, C., Loreti, Claudia, Piccinini, Giulia, Ricciardi, Diego, Castelli, Letizia, Fusco, Augusto, Bentivoglio, Anna Rita, Padua, Luca, Imbimbo I., Coraci D., Loreti C., Piccinini G., Ricciardi D., Castelli L. (ORCID:0000-0001-9455-3789), Fusco A., Bentivoglio A. R. (ORCID:0000-0002-9663-095X), and Padua L. (ORCID:0000-0003-2570-9326)

Abstract

Introduction: Parkinson’s disease (PD) is a neurodegenerative pathology characterized by motor and non-motor symptoms that often lead to several impairments. Many studies show the efficacy of different rehabilitation protocols aimed to improve balance and gait functions in PD patients. However, multiple factors may influence rehabilitation outcome. Recently, it has been observed as the cognitive reserve (CR) may influence the rehabilitation outcome, helping to address the patient toward technological or conventional rehabilitation. Our study investigated how CR may affect motor rehabilitation outcomes in PD patients who undergo virtual reality (VR) rehabilitation, aimed at improving walking and balance. Materials and methods: Thirty patients affected by idiopathic PD were enrolled. Patients underwent 12 sessions VR training, over 6 weeks (45 min). Six-Minute Walk Test (6MWT) and Berg Balance Scale (BBS) were used to assess walking and balance, respectively. CR was assessed by Cognitive Reserve Index questionnaire (CRIq). Results: Significant correlations between CR and change from baseline in walking and balance measures were found, with a significant positive correlation between CRIq and 6MWT (r=0.50, p=0.01) and between CRIq and BBS (r=0.41, p=0.04). Discussion: Our results showed that PD patients with higher CR treated with VR improved significantly more in their balance and walking distance than those with lower CR. The current study suggests that VR when aimed to improve balance and walking in PD patients is more effective in patients with higher CR.

Published
2021

28. What about the caregiver? A journey into Parkinson’s disease following the burden tracks

Author

Lo Monaco, Maria Rita, Di Stasio, Enrico, Ricciardi, Diego, Solito, Marcella, Petracca, Martina, Fusco, Domenico, Onder, Graziano, Landi, Giovanni, Zuccala', Giuseppe, Liperoti, Rosa, Cipriani, Maria Camilla, Brisi, C., Bernabei, Roberto, Silveri, Maria Caterina, Bentivoglio, Anna Rita, Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Di Stasio E. (ORCID:0000-0003-1047-4261), Ricciardi D., Solito M., Petracca M., Fusco D., Onder G. (ORCID:0000-0003-3400-4491), Landi G., Zuccala' G. (ORCID:0000-0002-2567-2220), Liperoti R. (ORCID:0000-0003-3740-1687), Cipriani M. C., Bernabei R. (ORCID:0000-0002-9197-004X), Silveri M. C. (ORCID:0000-0001-5012-0682), Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Lo Monaco, Maria Rita, Di Stasio, Enrico, Ricciardi, Diego, Solito, Marcella, Petracca, Martina, Fusco, Domenico, Onder, Graziano, Landi, Giovanni, Zuccala', Giuseppe, Liperoti, Rosa, Cipriani, Maria Camilla, Brisi, C., Bernabei, Roberto, Silveri, Maria Caterina, Bentivoglio, Anna Rita, Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Di Stasio E. (ORCID:0000-0003-1047-4261), Ricciardi D., Solito M., Petracca M., Fusco D., Onder G. (ORCID:0000-0003-3400-4491), Landi G., Zuccala' G. (ORCID:0000-0002-2567-2220), Liperoti R. (ORCID:0000-0003-3740-1687), Cipriani M. C., Bernabei R. (ORCID:0000-0002-9197-004X), Silveri M. C. (ORCID:0000-0001-5012-0682), and Bentivoglio A. R. (ORCID:0000-0002-9663-095X)

Abstract

Objectives: To investigate caregivers and patients characteristics related to different dimensions of burden in Parkinson’s disease (PD). Methods: 55 pairs of PD patients and caregivers were recruited. The burden was evaluated with the Caregiver Burden Inventory (CBI). Multivariate analysis was applied to evaluate the impact of caregivers’ and patients’ characteristics on the varying aspects of burden. Results: ADL score was the dominant predictor for the total score and all dimensions of CBI, except for the social burden, which is strongly predicted by the motor severity of PD. As one can easily imagine, the Total CBI decreases as the ADL score increases. Discussion: An increased appreciation for characteristics of caregiver burden is a fundamental aspect of the patient’s global evaluation. Clinicians may need to directly probe for these factors in the caregiver as they may not be elicited routinely.

Published
2021

29. P529Efficacy and safety of S-ICD implantation without use of defibrillation threshold testing: a retrospective multicentric observational study

Author

Ricciardi, D, primary, Picarelli, F, additional, Forleo, G B, additional, Di Belardino, N, additional, Bisignani, A, additional, Bisignani, G, additional, Santini, L, additional, Lavalle, C, additional, Pignalberi, C, additional, Picarelli, S, additional, Aurino, L, additional, Creta, A, additional, Calabrese, V, additional, Gioia, F A, additional, and Grigioni, F, additional

Published
2020
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30. P538Single- and Multi-Site Pacing Strategies for Optimal Cardiac Resynchronization Therapy: Impact on Device Longevity and Therapy Cost

Author

D"onofrio, A, primary, Bertini, M, additional, Infusino, T, additional, D Arienzo, G, additional, Misiani, A, additional, Bianchi, V, additional, Licciardello, G, additional, Savarese, G, additional, Russo, G, additional, Ricciardi, D, additional, Manzo, M, additional, Santini, L, additional, Ospizio, R, additional, Valsecchi, S, additional, and Forleo, G B, additional

Published
2020
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32. Impact of COVID-19 pandemic on the clinical activities related to arrhythmias and electrophysiology in Italy: results of a survey promoted by AIAC (Italian Association of Arrhythmology and Cardiac Pacing)

Author

Boriani, G., Palmisano, P., Guerra, F., Bertini, M., Zanotto, G., Lavalle, C., Notarstefano, P., Accogli, M., Bisignani, G., Forleo, G. B., Landolina, M., D'Onofrio, A., Ricci, R., De Ponti, R., Luise, R., Grieco, P., Pangallo, A., Quirino, G., Talarico, A., De Bonis, S., Carbone, A., De Simone, A., Nappi, F., Rotondi, F., Stabile, G., Uran, C., Balla, C., Boggian, G., Carinci, V., Barbato, G., Corzani, A., Sabbatani, P., Erminio, M., Imberti, J. F., Malavasi, N., Pastori, P., Quartieri, F., Bottoni, N., Saporito, D., Virzi, S., Sassone, B., Zardini, M., Placci, A., Ziacchi, M., Massaro, G., Adamo, F., Scaccia, A., Spampinato, A., Biscione, F., Castro, A., Cauti, F., Rossi, P., Cinti, C., Gatto, M., Kol, A., Narducci, M. L., Pelargonio, G., Patruno, N., Pignalberi, C., Ricci, R. P., Ricciardi, D., Santini, L., Tancredi, M., Di Belardino, N., Pentimalli, F., Zoni-Berisso, M., Belotti, G., Chieffo, E., Cilloni, S., Doni, L. A., Gardini, A., Malaspina, D., Mazzone, P., Della Bella, P., Negro, R., Perego, G. B., Rordorf, R., Cipolletta, L., Russo, A. D., Luzi, M., Amellone, C., Ebrille, E., Favro, E., Lucciola, M. T., Devecchi, C., Rametta, F., Devecchi, F., Matta, M., Sant'Andrea, A. O., Santagostino, M., Dell'Era, G., Candida, T. R., Bonfantino, V. M., Gianfrancesco, D., Guido, A., Pellegrino, P. L., Pisano, E. C. L., Rillo, M., Palama, Z., Sai, R., Santobuono, V. E., Favale, S., Scicchitano, P., Nissardi, V., Campisi, G., Sgarito, G., Arena, G., Casorelli, E., Fumagalli, S., Giaccardi, M., Nesti, M., Padeletti, M., Rossi, A., Piacenti, M., Del Greco, M., Catanzariti, D., Manfrin, M., Werner, R., Marini, M., Andreoli, C., Fedeli, F., Mazza, A., Pagnotta, F., Ridarelli, M., Molon, G., and Rossillo, A.

Subjects
Male, Cardiac pacing, 030204 cardiovascular system & hematology, Ablation, Cardiac Resynchronization Therapy, 0302 clinical medicine, Surveys and Questionnaires, Health care, Pandemic, Registries, 030212 general & internal medicine, Acute management, Secondary prevention, Atrial fibrillation, Arrhythmia, COVID-19, Emergency, Implantable cardioverter defibrillators, Pacemakers, Remote monitoring, Middle Aged, Electrophysiology, Italy, Emergency Medicine, Female, Coronavirus Infections, Adult, medicine.medical_specialty, Atrial fbrillation, Coronavirus disease 2019 (COVID-19), Pneumonia, Viral, Implantable cardioverter defbrillators, NO, 03 medical and health sciences, Physicians, medicine, Internal Medicine, Humans, Pandemics, Ablation, Arrhythmia, Atrial fbrillation, Emergency, Implantable cardioverter defbrillators, Pacemakers, Remote monitoring, COVID-19, Aged, business.industry, Outbreak, Arrhythmias, Cardiac, medicine.disease, Im - Original, Emergency medicine, business
Abstract

COVID-19 outbreak had a major impact on the organization of care in Italy, and a survey to evaluate provision of for arrhythmia during COVID-19 outbreak (March–April 2020) was launched. A total of 104 physicians from 84 Italian arrhythmia centres took part in the survey. The vast majority of participating centres (95.2%) reported a significant reduction in the number of elective pacemaker implantations during the outbreak period compared to the corresponding two months of year 2019 (50.0% of centres reported a reduction of > 50%). Similarly, 92.9% of participating centres reported a significant reduction in the number of implantable cardioverter-defibrillator (ICD) implantations for primary prevention, and 72.6% a significant reduction of ICD implantations for secondary prevention (> 50% in 65.5 and 44.0% of the centres, respectively). The majority of participating centres (77.4%) reported a significant reduction in the number of elective ablations (> 50% in 65.5% of the centres). Also the interventional procedures performed in an emergency setting, as well as acute management of atrial fibrillation had a marked reduction, thus leading to the conclusion that the impact of COVID-19 was disrupting the entire organization of health care, with a massive impact on the activities and procedures related to arrhythmia management in Italy. Electronic supplementary material The online version of this article (10.1007/s11739-020-02487-w) contains supplementary material, which is available to authorized users.

Published
2020

33. The effectiveness of telerehabilitation after hip or knee arthroplasty: A narrative review

Author

Ferrara, Pe, Codazza, S, Ferriero, G, Ricciardi, D, Foti, C, Maccauro, G, and Ronconi, G

Subjects
Settore MED/34, Knee Joint, Replacement, Quality of Life, Humans, Hip arthroplasty, Knee, Telerehabilitation, Arthroplasty, Replacement, Knee, Delivery of Health Care, Arthroplasty
Abstract

Telerehabilitation is defined as a set of tools, procedures, and protocols to deliver rehabilitation programs remotely. It involves the use of various communication technologies to efficiently provide rehabilitation services distantly or via some other remote environment. After an orthopedic procedure, physical rehabilitation is essential to restore joint's function, to improve quality of life as well as to relieve pain, to recovery independence. The effectiveness of telerehabilitation has been studied in literature. The aim of this narrative review is to update the current evidence, evaluate the efficacy of telerehabilitation after hip, and knee prosthesis surgery for end stage arthrosis. Results show that it is useful to integrate traditional interventions with telerehabilitation to accelerate efficiency in existing healthcare delivery systems. Future high-methodological-quality studies should be conducted to evaluate the long-term efficacy and safety of innovative technologies.

Published
2020

34. Prevalence of Obsessive-Compulsive Symptoms in Elderly Parkinson Disease Patients: A Case-Control Study

Author

Lo Monaco, Maria Rita, Di Stasio, Enrico, Zuccala', Giuseppe, Petracca, Martina, Genovese, Maria Daniela, Fusco, Domenico, Silveri, Maria Caterina, Liperoti, Rosa, Ricciardi, Diego, Cipriani, Maria Camilla, Laudisio, A., Bentivoglio, Anna Rita, Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Di Stasio E. (ORCID:0000-0003-1047-4261), Zuccala G. (ORCID:0000-0002-2567-2220), Petracca M., Genovese D., Fusco D., Silveri M. C. (ORCID:0000-0001-5012-0682), Liperoti R. (ORCID:0000-0003-3740-1687), Ricciardi D., Cipriani M. C., Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Lo Monaco, Maria Rita, Di Stasio, Enrico, Zuccala', Giuseppe, Petracca, Martina, Genovese, Maria Daniela, Fusco, Domenico, Silveri, Maria Caterina, Liperoti, Rosa, Ricciardi, Diego, Cipriani, Maria Camilla, Laudisio, A., Bentivoglio, Anna Rita, Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Di Stasio E. (ORCID:0000-0003-1047-4261), Zuccala G. (ORCID:0000-0002-2567-2220), Petracca M., Genovese D., Fusco D., Silveri M. C. (ORCID:0000-0001-5012-0682), Liperoti R. (ORCID:0000-0003-3740-1687), Ricciardi D., Cipriani M. C., and Bentivoglio A. R. (ORCID:0000-0002-9663-095X)

Abstract

Background: The clinical picture of obsessive-compulsive disorder encompasses a broad range of symptoms that are related to multiple psychological domains, including perception, cognition, emotion, and social relatedness. As obsessive-compulsive symptoms (OCS) frequently have an early onset, there are limited data about OCS in older populations (>= 65 years) and, in particular, in elderly subjects with Parkinson disease (PD). Objective: This study aimed to estimate the prevalence of OCS using a self-report measure (Obsessive-Compulsive Inventory-Revised) and to identify associated sociodemographic and clinical factors in a sample of elderly PD patients compared to a comparison group of similarly aged healthy volunteers. Results: The mean age was 74 +/- 6 years in the PD patients and 73 +/- 7 years in the comparison group. The mean disease duration was 9.6 +/- 5.8 years. Among the PD patients, 30.7% reported at least one OCS or a related disorder compared to 21.1% in the comparison group. Hoarding was significantly more common in PD patients than in the comparison group. Conclusions: Subclinical OCS were present at a high percentage in both PD patients and comparison group. The OCS phenotype in PD may present differently, as hoarding was more common in PD patients.

Published
2020

35. Comparison of virtual reality rehabilitation and conventional rehabilitation in Parkinson's disease: a randomised controlled trial

Author

Pazzaglia, Costanza, Imbimbo, Isabella, Tranchita, E, Minganti, C, Ricciardi, Diego, Lo Monaco, Maria Rita, Parisi, Carmelo Maria Antonio, Padua, Luca, Pazzaglia, C, Imbimbo, I, Ricciardi, D, Lo Monaco, R (ORCID:0000-0002-1457-7981), Parisi, A, Padua, L (ORCID:0000-0003-2570-9326), Pazzaglia, Costanza, Imbimbo, Isabella, Tranchita, E, Minganti, C, Ricciardi, Diego, Lo Monaco, Maria Rita, Parisi, Carmelo Maria Antonio, Padua, Luca, Pazzaglia, C, Imbimbo, I, Ricciardi, D, Lo Monaco, R (ORCID:0000-0002-1457-7981), Parisi, A, and Padua, L (ORCID:0000-0003-2570-9326)

Abstract

Objective To compare a 6-week virtual reality (VR) rehabilitation programme with a conventional rehabilitation programme in patients with Parkinson's disease.Design Prospective, single-blinded, randomised controlled trial.Setting Outpatients.Participants Fifty-one patients with Parkinson's disease were assigned at random to a VR rehabilitation programme or a conventional rehabilitation programme.Interventions Both programmes ran for 6 consecutive weeks, with a 40-minute session three times per week.Main outcome measures The Balance Berg Scale (BBS) was used to measure balance. Secondary outcome measures were: Dynamic Gait Index (DGI) to evaluate ability to adapt gait to complex walking tasks; Disabilities of the Arm, Shoulder and Hand (DASH) scale to measure performance of the upper limb; and Short Form 36 (SF-36) to evaluate quality of life.Results The VR rehabilitation programme led to an increase in BBS score {45.6 [standard deviation (SD) 7.9] vs 49.2 (SD 8.1), mean difference 3.6, 95% confidence interval (CI) 1.3 to 5.9; P= 0.0031, DGI score [18.7 (SD 4.7) vs 20.2 (SD 4.2), mean difference 1.6, 95% CI 0.6 to 2.5; P = 0.003] and SF-36 mental composite score [37.7 (SD 11.4) vs 43.5 (SD 9.2), mean difference 5.8, 95% CI 0.4 to 11.3; P = 0.037], and a decrease in DASH scale score [29.6 (SD 17.5) vs 21.6 (SD 15.1), mean difference -7.9, 95% CI -13.7 to -2.2; P= 0.009]. In contrast, the conventional rehabilitation programme only led to a decrease in DASH scale score [30.3 (SD 18.1) vs 25.1 (SD 15.8), mean difference -5.2, 95% CI -8.8 to -1.5; P = 0.007].Conclusion These findings suggest that rehabilitation is useful in Parkinson's disease, and the VR rehabilitation programme was more effective in determining overall improvement than the conventional rehabilitation programme. (C) 2019 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

Published
2020

36. Comparison of virtual reality rehabilitation and conventionalrehabilitation in Parkinson’s disease: a randomised controlledtrial

Author

Pazzaglia, Costanza, Imbimbo, Isabella, Tranchita, E, Minganti, C, Ricciardi, Diego, Lo Monaco, Maria Rita, Parisi, A, Padua, Luca, Pazzaglia C, Imbimbo I, Ricciardi D, Lo Monaco R (ORCID:0000-0002-1457-7981), Padua L (ORCID:0000-0003-2570-9326), Pazzaglia, Costanza, Imbimbo, Isabella, Tranchita, E, Minganti, C, Ricciardi, Diego, Lo Monaco, Maria Rita, Parisi, A, Padua, Luca, Pazzaglia C, Imbimbo I, Ricciardi D, Lo Monaco R (ORCID:0000-0002-1457-7981), and Padua L (ORCID:0000-0003-2570-9326)

Abstract

OBJECTIVE: To compare a 6-week virtual reality (VR) rehabilitation programme with a conventional rehabilitation programme in patients with Parkinson's disease. DESIGN: Prospective, single-blinded, randomised controlled trial. SETTING: Outpatients. PARTICIPANTS: Fifty-one patients with Parkinson's disease were assigned at random to a VR rehabilitation programme or a conventional rehabilitation programme. INTERVENTIONS: Both programmes ran for 6 consecutive weeks, with a 40-minute session three times per week. MAIN OUTCOME MEASURES: The Balance Berg Scale (BBS) was used to measure balance. Secondary outcome measures were: Dynamic Gait Index (DGI) to evaluate ability to adapt gait to complex walking tasks; Disabilities of the Arm, Shoulder and Hand (DASH) scale to measure performance of the upper limb; and Short Form 36 (SF-36) to evaluate quality of life. RESULTS: The VR rehabilitation programme led to an increase in BBS score {45.6 [standard deviation (SD) 7.9] vs 49.2 (SD 8.1), mean difference 3.6, 95% confidence interval (CI) 1.3 to 5.9; P=0.003}, DGI score [18.7 (SD 4.7) vs 20.2 (SD 4.2), mean difference 1.6, 95% CI 0.6 to 2.5; P=0.003] and SF-36 mental composite score [37.7 (SD 11.4) vs 43.5 (SD 9.2), mean difference 5.8, 95% CI 0.4 to 11.3; P=0.037], and a decrease in DASH scale score [29.6 (SD 17.5) vs 21.6 (SD 15.1), mean difference -7.9, 95% CI -13.7 to -2.2; P=0.009]. In contrast, the conventional rehabilitation programme only led to a decrease in DASH scale score [30.3 (SD 18.1) vs 25.1 (SD 15.8), mean difference -5.2, 95% CI -8.8 to -1.5; P=0.007]. CONCLUSION: These findings suggest that rehabilitation is useful in Parkinson's disease, and the VR rehabilitation programme was more effective in determining overall improvement than the conventional rehabilitation programme.

Published
2020

37. Safinamide as an adjunct therapy in older patients with Parkinson’s disease: a retrospective study

Author

Lo Monaco, Maria Rita, Petracca, Martina, Vetrano, D. L., Di Stasio, Enrico, Fusco, Domenico, Ricciardi, Diego, Laudisio, A., Zuccala', Giuseppe, Onder, Graziano, Bentivoglio, Anna Rita, Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Petracca M., Di Stasio E. (ORCID:0000-0003-1047-4261), Fusco D., Ricciardi D., Zuccala G. (ORCID:0000-0002-2567-2220), Onder G. (ORCID:0000-0003-3400-4491), Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Lo Monaco, Maria Rita, Petracca, Martina, Vetrano, D. L., Di Stasio, Enrico, Fusco, Domenico, Ricciardi, Diego, Laudisio, A., Zuccala', Giuseppe, Onder, Graziano, Bentivoglio, Anna Rita, Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Petracca M., Di Stasio E. (ORCID:0000-0003-1047-4261), Fusco D., Ricciardi D., Zuccala G. (ORCID:0000-0002-2567-2220), Onder G. (ORCID:0000-0003-3400-4491), and Bentivoglio A. R. (ORCID:0000-0002-9663-095X)

Abstract

Background: Safinamide, as a levodopa adjunct, is effective in reducing motor fluctuations in Parkinson’s disease (PD) patients; however, scarce evidence is available regarding its use in older PD patients. Aim: To evaluate the safety and tolerability of safinamide as an adjunct therapy in patients aged ≥ 60 years with advanced PD. Methods: A retrospective study including 203 PD patients admitted to a geriatric day hospital, who were evaluated following an extensive clinical protocol. Safinamide use was categorized as never used, ongoing, and withdrawn. Potential correlations of Safinamide withdrawal were investigated in stepwise backward logistic regression models. Results: A total of 44 out of 203 participants were current or former users of Safinamide. Overall, 14 (32%) patients discontinued due to treatment-emergent adverse events (TEAEs). Withdrawal was not associated with older age. Conclusions: Safinamide as an adjunct therapy in patients aged ≥ 60 years with advanced PD was found to be safe and well-tolerated in older patients. There were no specific demographic or clinical characteristics associated with suspension.

Published
2020

39. Immediate effects of rhythmic auditory stimulation on gait kinematics in Parkinson's disease ON/OFF medication

Author

Erra, Carmen, Mileti, I, Germanotta, Marco, Petracca, Martina, Imbimbo, Isabella, De Biase, A, Rossi, S, Ricciardi, Diego, Pacilli, A, Di Sipio, E, Palermo, E, Bentivoglio, Anna Rita, Padua, Luca, Erra C, Germanotta M, Petracca M, Imbimbo I, Ricciardi D, Bentivoglio AR (ORCID:0000-0002-9663-095X), Padua L. (ORCID:0000-0003-2570-9326), Erra, Carmen, Mileti, I, Germanotta, Marco, Petracca, Martina, Imbimbo, Isabella, De Biase, A, Rossi, S, Ricciardi, Diego, Pacilli, A, Di Sipio, E, Palermo, E, Bentivoglio, Anna Rita, Padua, Luca, Erra C, Germanotta M, Petracca M, Imbimbo I, Ricciardi D, Bentivoglio AR (ORCID:0000-0002-9663-095X), and Padua L. (ORCID:0000-0003-2570-9326)

Abstract

OBJECTIVE: Gait impairment is a highly disabling symptom for Parkinson's disease (PD) patients. Rhythmic auditory stimulation (RAS), has shown to improve spatio-temporal gait parameters in PD, but only a few studies have focused on their effects on gait kinematics, and the ideal stimulation frequency has still not been identified. METHODS: We enrolled 30 PD patients and 18 controls. Patients were evaluated under two conditions (with (ON), and without (OFF) medications) with three different RAS frequencies (90%, 100%, and 110% of the patient's preferred walking cadence). Spatial-temporal parameters, joint angles and gait phases distribution were evaluated. A novel global index (GPQI) was used to quantify the difference in gait phase distribution. RESULTS: Along with benefits in spatial-temporal parameters, GPQI improved significantly with RAS at a frequency of 110% for both ON and OFF medication conditions. In the most severe patients, the same result was observed also with RAS at 100%. CONCLUSIONS: RAS administration, at a frequency of 110% of the preferred walking frequency, can be beneficial in improving the gait pattern in PD patients. SIGNIFICANCE: When rhythmic auditory stimulation is provided to patients with PD, the selection of an adequate frequency of stimulation can optimize their effects on gait pattern.

Published
2019

40. P454Validation of a new LVH ECG criterion in a single center wide population

Author

Ricciardi, D, primary, Vetta, G, additional, Nenna, A, additional, Migliaro, G, additional, Calabrese, V, additional, Venditti, A, additional, Urbano, M, additional, Picarelli, F, additional, Ragni, L, additional, Vetta, F, additional, Melfi, R, additional, Mangiacapra, F, additional, Di Belardino, N, additional, and Di Sciascio, G, additional

Published
2018
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42. Laterality in Parkinson's disease may predict motor and visual imagery abilities

Author

Lo Monaco, Maria Rita, Laudisio, Alice, Fusco, Domenico, Vetrano, Davide Liborio, Ricciardi, Diego, Delle Donne, Valentina, Proietti, Francesca, Zuccala', Giuseppe, Silveri, Maria Caterina, Lo Monaco MR (ORCID:0000-0002-1457-7981), Laudisio A, Fusco D, Vetrano DL, Ricciardi D, Delle Donne V, Zuccalà G (ORCID:0000-0002-2567-2220), Silveri MC (ORCID:0000-0001-5012-0682), Lo Monaco, Maria Rita, Laudisio, Alice, Fusco, Domenico, Vetrano, Davide Liborio, Ricciardi, Diego, Delle Donne, Valentina, Proietti, Francesca, Zuccala', Giuseppe, Silveri, Maria Caterina, Lo Monaco MR (ORCID:0000-0002-1457-7981), Laudisio A, Fusco D, Vetrano DL, Ricciardi D, Delle Donne V, Zuccalà G (ORCID:0000-0002-2567-2220), and Silveri MC (ORCID:0000-0001-5012-0682)

Abstract

Experimental evidence suggests that motor imagery (MI) engages the same neural substrates supporting actual motor activities and is likely impaired when such substrates are damaged, as in Parkinson's disease (PD). MI intuitively relies on visual imagery (VI), because mental simulations of physical movements depend on the visual retrieval of these movements. Although VI is generally considered a right hemispheric function, the hemispheric dominance of MI is still in dispute. Disparities in sidedness of motor disturbances are a distinctive feature of PD, and recent findings indicate that such disparities may similarly characterize cognition. Specifically, the deficits observed may depend upon which hemisphere is principally involved. Essentially, MI and VI are cognitive tasks subject to differential impairment and reflecting the prevalence of hemispheric impairment in PD. Motor imagery (assessed by the Vividness of Motor Imagery Questionnaire [VMIQ]) and VI (assessed by the Vividness of Visual Imagery Questionnaire [VVIQ] and Test of Visual Imagery Control [TVIC]) were examined in patients with asymmetric PD and in healthy elderly control subjects (HC group). VMIQ scores were similar in PD laterality subsets and the HC group, but VVIQ scores were significantly lower in both PD groups compared with the HC group. TVIC scores were significantly lower in the presence of left motor (right hemispheric) impairment and were predictive of left motor (right hemispheric) impairment. We suspect that MI is strongly reliant on VI and that language may mediate these two functions, to the extent that both are evoked through verbal stimuli. Working memory, both visual and verbal, is also involved in MI and VI tasks. Without due attention to laterality of symptoms, any training incorporating MI and VI may not deliver expected outcomes in the setting of asymmetric PD symptomatology.

Published
2018

43. Antimicrobial resistance patterns of Enterobacteriaceae in European wild bird species admitted in a wildlife rescue centre

Author

Giacopello, Cristina, Foti, Maria, Mascetti, A., Grosso, F., Ricciardi, D., Fisichella, Vittorio, and LO PICCOLO, Francesco

Subjects
Birds, Europe, Enterobacteriaceae, Drug Resistance, Bacterial, Antimicrobial resistance, enterobacteriaceae, rescue centre, wild birds, Animals, Animals, Wild, Gastrointestinal Microbiome
Abstract

Wild birds have been considered to be reservoirs of enteric human pathogens and vectors of resistance dissemination to the environment. During annual migration, they potentially play a role in the epidemiology of human associated zoonoses. The aim of this study was to investigate the frequency of isolation and antimicrobial susceptibility profiles of Enterobacteriaceae members isolated from cloacal swabs of common European wild birds. Fifty-five cloacal swabs were taken during birds' entrance evaluation in a rescue centre for injured wild birds in the Province of Messina (Sicily, Italy). All samples were examined for the presence of members of the family Enterobacteriaceae using standard methods and on the isolated strains antibiotic susceptibility testing was performed. Eighty three Enterobacteriaceae strains were isolated from raptors, waterbirds and passerines. The bacterial species isolated were: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Citrobacter freundii, Enterobacter cloacae, Klebsiella oxytoca, Salmonella Typhimurium, Escherichia vulneris, Enterobacter amnigenus biogroup 2, Salmonella Duesseldorf and Hafnia alvei. The isolates showed significant frequencies of antibiotic resistance. Multiresistance to three or more groups of antibiotics also occurred. None of them have shown a phenotypic Extended Spectrum Beta Lactamase (ESBL) profile.

Published
2016

47. CHRONIC GRAFT Vs HOST DISEASE OF THE GENITAL TRACT: DIAGNOSIS, CLINICAL IMPACT AND MANAGEMENT FROM SURVEILLANCE PROGRAM IN A PRELIMINARY COHORT

Author

MAROTTA, SERENA, PAGLIUCA, SIMONA, BASILE, SANTINA, PANE, FABRIZIO, DE ROSA, GENNARO, RISITANO, ANTONIO MARIA, Ricciardi D., Bertrando A., de Rosa N., Cardano F., Piccoli R., Marotta, Serena, Ricciardi, D., Bertrando, A., de Rosa, N., Pagliuca, Simona, Basile, Santina, Cardano, F., Pane, Fabrizio, DE ROSA, Gennaro, Piccoli, R., and Risitano, ANTONIO MARIA

Published
2013

48. The impact of cognitive reserve on the effectiveness of balance rehabilitation in Parkinson's disease

Author

Piccinini, Giulia, Imbimbo, Isabella, Ricciardi, Diego, Coraci, Daniele, Santilli, C, Lo Monaco, Maria Rita, Loreti, Claudia, Vulpiani, Mc, Silveri, Maria Caterina, Padua, Luca, Piccinini G, Imbimbo I, Ricciardi D, Coraci D, Lo Monaco MR (ORCID:0000-0002-1457-7981), Loreti C, Silveri MC (ORCID:0000-0001-5012-0682), Padua L (ORCID:0000-0003-2570-9326), Piccinini, Giulia, Imbimbo, Isabella, Ricciardi, Diego, Coraci, Daniele, Santilli, C, Lo Monaco, Maria Rita, Loreti, Claudia, Vulpiani, Mc, Silveri, Maria Caterina, Padua, Luca, Piccinini G, Imbimbo I, Ricciardi D, Coraci D, Lo Monaco MR (ORCID:0000-0002-1457-7981), Loreti C, Silveri MC (ORCID:0000-0001-5012-0682), and Padua L (ORCID:0000-0003-2570-9326)

Abstract

BACKGROUND: Cognitive reserve (CR) can be considered an active expression of brain resilience in response to damage. Several studies have shown the influence of CR on cognitive impairment and its relationship with cognitive function in Parkinson's disease (PD). AIM: To show if CR influences the effectiveness of balance rehabilitation in PD patients who performed a conventional rehabilitative treatment. DESIGN: Observational longitudinal study. SETTING: Neurology outpatient Unit, University Hospital. POPULATION: Fifty-three patients affected by idiopathic PD, stage 2-3 at the Hoehn and Yahr scale. METHODS: Each patient underwent 32 group sessions of conventional rehabilitative treatment. At baseline, patient CR was assessed by the Cognitive Reserve Index questionnaire (CRIq). The primary outcome was the evaluation of static and dynamic balance modifications, induced by the treatment, through the Berg Balance Scale (BBS), assessed at T0 and T1. Mini Mental State Examination, Unified Parkinson's Disease Rating Scale Part III (clinician-scored monitored motor evaluation) and Brief Intelligence Test were assessed only at T0 and used as descriptive variables. RESULTS: Considering the clinically meaningful change, BBS improved in 26% of patients worsened in 2% and was unchanged in 72%. BBS score significantly improved in older patients, and in those with lower CRI total score. A significant inverse correlation was observed between changes in BBS and work and education related CR. Patients with lower baseline BBS score showed more improvement in balance. CONCLUSIONS: We found an inverse correlation between CR level and balance improvement in PD patients who underwent conventional rehabilitation: higher improvement in BBS was observed in those with a lower CRI score. This may suggest that patients with higher CRI could benefit from more stimulating modes of non conventional rehabilitation (e.g. robotic, virtual reality). CLINICAL REHABILITATION IMPACT: Rehabilitation should

Published
2017

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