9,339 results on '"Riboli A"'
Search Results
2. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.
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Wang, Anqi, Shen, Jiayi, Rodriguez, Alex, Saunders, Edward, Chen, Fei, Janivara, Rohini, Darst, Burcu, Sheng, Xin, Xu, Yili, Chou, Alisha, Benlloch, Sara, Dadaev, Tokhir, Brook, Mark, Plym, Anna, Sahimi, Ali, Hoffman, Thomas, Takahashi, Atushi, Matsuda, Koichi, Momozawa, Yukihide, Fujita, Masashi, Laisk, Triin, Figuerêdo, Jéssica, Muir, Kenneth, Ito, Shuji, Liu, Xiaoxi, Uchio, Yuji, Kubo, Michiaki, Kamatani, Yoichiro, Lophatananon, Artitaya, Wan, Peggy, Andrews, Caroline, Lori, Adriana, Choudhury, Parichoy, Schleutker, Johanna, Tammela, Teuvo, Sipeky, Csilla, Auvinen, Anssi, Giles, Graham, Southey, Melissa, MacInnis, Robert, Cybulski, Cezary, Wokolorczyk, Dominika, Lubinski, Jan, Rentsch, Christopher, Cho, Kelly, Mcmahon, Benjamin, Neal, David, Donovan, Jenny, Hamdy, Freddie, Martin, Richard, Nordestgaard, Borge, Nielsen, Sune, Weischer, Maren, Bojesen, Stig, Røder, Andreas, Stroomberg, Hein, Batra, Jyotsna, Chambers, Suzanne, Horvath, Lisa, Clements, Judith, Tilly, Wayne, Risbridger, Gail, Gronberg, Henrik, Aly, Markus, Szulkin, Robert, Eklund, Martin, Nordstrom, Tobias, Pashayan, Nora, Dunning, Alison, Ghoussaini, Maya, Travis, Ruth, Key, Tim, Riboli, Elio, Park, Jong, Sellers, Thomas, Lin, Hui-Yi, Albanes, Demetrius, Weinstein, Stephanie, Cook, Michael, Mucci, Lorelei, Giovannucci, Edward, Lindstrom, Sara, Kraft, Peter, Hunter, David, Penney, Kathryn, Turman, Constance, Tangen, Catherine, Goodman, Phyllis, Thompson, Ian, Hamilton, Robert, Fleshner, Neil, Finelli, Antonio, Parent, Marie-Élise, Stanford, Janet, Ostrander, Elaine, Koutros, Stella, Beane Freeman, Laura, Stampfer, Meir, Wolk, Alicja, and Håkansson, Niclas
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Humans ,Male ,Black People ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Hispanic or Latino ,Polymorphism ,Single Nucleotide ,Prostatic Neoplasms ,Risk Factors ,White People ,Asian People - Abstract
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies. We identified 187 novel risk variants for prostate cancer, increasing the total number of risk variants to 451. An externally replicated multi-ancestry GRS was associated with risk that ranged from 1.8 (per standard deviation) in African ancestry men to 2.2 in European ancestry men. The GRS was associated with a greater risk of aggressive versus non-aggressive disease in men of African ancestry (P = 0.03). Our study presents novel prostate cancer susceptibility loci and a GRS with effective risk stratification across ancestry groups.
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- 2023
3. Flexible Physical Unclonable Functions based on non-deterministically distributed Dye-Doped Fibers and Droplets
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Bruno, Mauro Daniel Luigi, Lio, Giuseppe Emanuele, Ferraro, Antonio, Nocentini, Sara, Papuzzo, Giuseppe, Forestiero, Agostino, Desiderio, Giovanni, De Santo, Maria Penelope, Wiersma, Diederik Sybolt, Caputo, Roberto, Golemme, Giovanni, Riboli, Francesco, and Barberi, Riccardo Cristoforo
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Condensed Matter - Materials Science ,Condensed Matter - Soft Condensed Matter ,Electrical Engineering and Systems Science - Image and Video Processing ,Physics - Applied Physics ,Physics - Chemical Physics ,Physics - Optics - Abstract
The development of new anti-counterfeiting solutions is a constant challenge and involves several research fields. Much interest is devoted to systems that are impossible to clone, based on the Physical Unclonable Function (PUF) paradigm. In this work, new strategies based on electrospinning and electrospraying of dye-doped polymeric materials are presented for the manufacturing of flexible free-standing films that embed different PUF keys. Films can be used to fabricate anticounterfeiting labels having three encryption levels: i) a map of fluorescent polymer droplets, with non deterministic positions on a dense yarn of polymer nanofibers; ii) a characteristic fluorescence spectrum for each label; iii) a challenge-response pairs (CRPs) identification protocol based on the strong nature of the physical unclonable function. The intrinsic uniqueness introduced by the deposition techniques encodes enough complexity into the optical anti-counterfeiting tag to generate thousands of cryptographic keys. The simple and cheap fabrication process as well as the multilevel authentication makes such colored polymeric unclonable tags a practical solution in the secure protection of merchandise in our daily life.
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- 2023
4. Unlocking optical coupling tunability in epsilon-near-zero metamaterials through liquid crystal nanocavities
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Lio, Giuseppe Emanuele, Ferraro, Antonio, Zappone, Bruno, Parka, Janusz, Schab-Balcerzak, Ewa, Umeton, Cesare Paolo, Riboli, Francesco, Kowerdziej, Rafał, and Caputo, Roberto
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Physics - Optics ,Physics - Applied Physics - Abstract
Epsilon-near-zero (ENZ) metamaterials represent a powerful toolkit for selectively transmitting and localizing light through cavity resonances, enabling the study of mesoscopic phenomena and facilitating the design of photonic devices. In this experimental study, we demonstrate the feasibility of engineering and actively controlling cavity modes, as well as tuning their mutual coupling, in an ENZ multilayer structure. Specifically, by employing a high-birefringence liquid crystal film as a tunable nanocavity, the polarization-dependent coupling of resonant modes with narrow spectral width and spatial extent was achieved. Surface forces aparatus (SFA) allowed us to continuously and precisely control the thickness of the liquid crystal film contained between the nanocavities and thus vary the detuning between the cavity modes. Hence, we were able to manipulate nanocavities anti-crossing behaviors. The suggested methodology unlocks the full potential of tunable optical coupling in epsilon-near-zero metamaterials and provides a versatile approach to the creation of tunable photonic devices, including bio-photonic sensors, and/or tunable planar metamaterials for on-chip spectrometers., Comment: 9 pages and 5 figures, it is also included the Supporting Information
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- 2023
5. Optical Limiter Based on PT-Symmetry Breaking of Reflectionless Modes
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Riboli, F., Kononchuk, R., Tommasi, F., Boschetti, A., Suwunnarat, S., Anisimov, I., Vitebskiy, I., Wiersma, D. S., Cavalieri, S., Kottos, T., and Chabanov, A. A.
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Physics - Optics - Abstract
The application of parity-time (PT) symmetry in optics, especially PT-symmetry breaking, has attracted considerable attention as a novel approach to controlling light propagation. Here, we report optical limiting by two coupled optical cavities with a PT-symmetric spectrum of reflectionless modes. The optical limiting is related to broken PT symmetry due to light-induced changes in one of the cavities. Our experimental implementation is a three-mirror resonator of alternating layers of ZnS and cryolite with a PT-symmetric spectral degeneracy of two reflectionless modes. The optical limiting is demonstrated by measurements of single 532-nm 6-ns laser pulses. At fluences below 10 mJ/cm2, the multilayer exhibits a flat-top passband at 532 nm. At higher fluences, laser heating combined with the thermo-optic effect in ZnS leads to cavity detuning and PT-symmetry breaking of the reflectionless modes. As a result, the entire multilayer structure quickly becomes highly reflective, protecting itself from laser-induced damage. The cavity detuning mechanism can differ at much higher limiting thresholds and include nonlinearity., Comment: 17 pages, 5 figures
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- 2023
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6. Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization.
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Canzian, Federico, Du, Mengmeng, Gallinger, Steven, Giles, Graham, Goodman, Phyllis, Haiman, Christopher, Kogevinas, Manolis, Kooperberg, Charles, LeMarchand, Loic, Neale, Rachel, Visvanathan, Kala, White, Emily, Albanes, Demetrius, Andreotti, Gabriella, Babic, Ana, Berndt, Sonja, Brais, Lauren, Brennan, Paul, Buring, Julie, Rabe, Kari, Bamlet, William, Chanock, Stephen, Fuchs, Charles, Gaziano, J, Giovannucci, Edward, Hackert, Thilo, Hassan, Manal, Katzke, Verena, Kurtz, Robert, Lee, I-Min, Malats, Núria, Murphy, Neil, Oberg, Ann, Orlow, Irene, Porta, Miquel, Real, Francisco, Rothman, Nathaniel, Sesso, Howard, Silverman, Debra, Thompson, Ian, Wactawski-Wende, Jean, Wang, Xiaoliang, Wentzensen, Nicolas, Yu, Herbert, Zeleniuch-Jacquotte, Anne, Yu, Kai, Wolpin, Brian, Duell, Eric, Li, Donghui, Hung, Rayjean, Perdomo, Sandra, McCullough, Marjorie, Freedman, Neal, Patel, Alpa, Peters, Ulrike, Riboli, Elio, Sund, Malin, Tjønneland, Anne, Zhong, Jun, Van Den Eeden, Stephen, Kraft, Peter, Risch, Harvey, Amundadottir, Laufey, Klein, Alison, Stolzenberg-Solomon, Rachael, Antwi, Samuel, King, Sontoria, Veliginti, Swathi, Brouwers, Martijn, Ren, Zhewen, Zheng, Wei, Setiawan, Veronica, Wilkens, Lynne, Shu, Xiao-Ou, Arslan, Alan, Beane Freeman, Laura, and Bracci, Paige
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Humans ,Non-alcoholic Fatty Liver Disease ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Mendelian Randomization Analysis ,Pancreatic Neoplasms ,Obesity ,Polymorphism ,Single Nucleotide - Abstract
BACKGROUND: There are conflicting data on whether nonalcoholic fatty liver disease (NAFLD) is associated with susceptibility to pancreatic cancer. Using Mendelian randomization (MR), we investigated the relationship between genetic predisposition to NAFLD and risk for pancreatic cancer. METHODS: Data from genome-wide association studies (GWAS) within the Pancreatic Cancer Cohort Consortium (PanScan; cases n = 5,090, controls n = 8,733) and the Pancreatic Cancer Case Control Consortium (PanC4; cases n = 4,163, controls n = 3,792) were analyzed. We used data on 68 genetic variants with four different MR methods [inverse variance weighting (IVW), MR-Egger, simple median, and penalized weighted median] separately to predict genetic heritability of NAFLD. We then assessed the relationship between each of the four MR methods and pancreatic cancer risk, using logistic regression to calculate ORs and 95% confidence intervals (CI), adjusting for PC risk factors, including obesity and diabetes. RESULTS: No association was found between genetically predicted NAFLD and pancreatic cancer risk in the PanScan or PanC4 samples [e.g., PanScan, IVW OR, 1.04; 95% confidence interval (CI), 0.88-1.22; MR-Egger OR, 0.89; 95% CI, 0.65-1.21; PanC4, IVW OR, 1.07; 95% CI, 0.90-1.27; MR-Egger OR, 0.93; 95% CI, 0.67-1.28]. None of the four MR methods indicated an association between genetically predicted NAFLD and pancreatic cancer risk in either sample. CONCLUSIONS: Genetic predisposition to NAFLD is not associated with pancreatic cancer risk. IMPACT: Given the close relationship between NAFLD and metabolic conditions, it is plausible that any association between NAFLD and pancreatic cancer might reflect host metabolic perturbations (e.g., obesity, diabetes, or metabolic syndrome) and does not necessarily reflect a causal relationship between NAFLD and pancreatic cancer.
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- 2023
7. Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort
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Matta, Komodo, Viallon, Vivian, Botteri, Edoardo, Peveri, Giulia, Dahm, Christina, Nannsen, Anne Østergaard, Olsen, Anja, Tjønneland, Anne, Elbaz, Alexis, Artaud, Fanny, Marques, Chloé, Kaaks, Rudolf, Katzke, Verena, Schulze, Matthias B., Llanaj, Erand, Masala, Giovanna, Pala, Valeria, Panico, Salvatore, Tumino, Rosario, Ricceri, Fulvio, Derksen, Jeroen W. G., Nøst, Therese Haugdahl, Sandanger, Torkjel M., Borch, Kristin Benjaminsen, Quirós, J. Ramón, Castro-Espin, Carlota, Sánchez, Maria-José, Atxega, Amaia Aizpurua, Cirera, Lluís, Guevara, Marcela, Manjer, Jonas, Tin Tin, Sandar, Heath, Alicia, Touvier, Mathilde, Goldberg, Marcel, Weiderpass, Elisabete, Gunter, Marc J., Freisling, Heinz, Riboli, Elio, and Ferrari, Pietro
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- 2024
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8. Long-COVID autonomic syndrome in working age and work ability impairment
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Rinaldi, Luca, Rigo, Stefano, Pani, Margherita, Bisoglio, Andrea, Khalaf, Kareem, Minonzio, Maura, Shiffer, Dana, Romeo, Maria Angela, Verzeletti, Paolo, Ciccarelli, Michele, Bordoni, Maria Grazia, Stranges, Saverio, Riboli, Elio, Furlan, Raffaello, and Barbic, Franca
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- 2024
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9. Prospective associations of leucocyte subtypes and obesity with the risk of developing cutaneous malignant melanoma in the UK Biobank cohort
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Christakoudi, Sofia, Tsilidis, Konstantinos K., and Riboli, Elio
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- 2024
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10. Public libraries to promote public health and wellbeing: a cross-sectional study of community-dwelling adults
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Karki, Manisha, El Asmar, Marie Line, Sasco, Eva Riboli, and El-Osta, Austen
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- 2024
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11. Links between the genetic determinants of morning plasma cortisol and body shape: a two-sample Mendelian randomisation study
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Christakoudi, Sofia, Asimakopoulos, Alexandros-Georgios, Riboli, Elio, and Tsilidis, Konstantinos K.
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- 2024
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12. Exploring the link between self-management of migraine and emotional wellbeing: a cross-sectional study of community-dwelling migraine sufferers
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Filzmoser, Nicola, Webber, Iman, Kerr, Gabriele, Alaa, Aos, El Asmar, Marie Iine, Karki, Manisha, Riboli-Sasco, Eva, and El-Osta, Austen
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- 2024
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13. All-optical multilevel physical unclonable functions
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Nocentini, Sara, Rührmair, Ulrich, Barni, Mauro, Wiersma, Diederik S., and Riboli, Francesco
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- 2024
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14. Lifestyle changes in middle age and risk of cancer: evidence from the European Prospective Investigation into Cancer and Nutrition
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Botteri, Edoardo, Peveri, Giulia, Berstad, Paula, Bagnardi, Vincenzo, Hoff, Geir, Heath, Alicia K., Cross, Amanda J., Vineis, Paolo, Dossus, Laure, Johansson, Mattias, Freisling, Heinz, Matta, Komodo, Huybrechts, Inge, Chen, Sairah L. F., B. Borch, Kristin, Sandanger, Torkjel M., H. Nøst, Therese, Dahm, Christina C., Antoniussen, Christian S., Tin Tin, Sandar, Fournier, Agnès, Marques, Chloé, Artaud, Fanny, Sánchez, Maria-José, Guevara, Marcela, Santiuste, Carmen, Agudo, Antonio, Bajracharya, Rashmita, Katzke, Verena, Ricceri, Fulvio, Agnoli, Claudia, Bergmann, Manuela M., Schulze, Matthias B., Panico, Salvatore, Masala, Giovanna, Tjønneland, Anne, Olsen, Anja, Stocks, Tanja, Manjer, Jonas, Aizpurua-Atxega, Amaia, Weiderpass, Elisabete, Riboli, Elio, Gunter, Marc J., and Ferrari, Pietro
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- 2024
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15. Breakdown of self-similarity in light transport
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Pini, Ernesto, Mazzamuto, Giacomo, Riboli, Francesco, Wiersma, Diederik S., and Pattelli, Lorenzo
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Physics - Optics ,Condensed Matter - Disordered Systems and Neural Networks - Abstract
Transport processes underpin a multitude of phenomena, ranging from the propagation of atoms on lattices, to the mobility patterns of microorganisms and earthquakes, to name a few. The dynamics of these processes is very rich and key to understanding the complex nature of the underlying physics, but the way in which we classify them is often too simplistic to fully reflect this complexity. Here, we report on the experimental observation of a breakdown of self-similar propagation for light inside a scattering medium - a transport regime exhibiting different scaling rates for each spatial moment of the associated probability distribution. Notably, we show that this phenomenon arises for light waves even in the simple case of isotropic and homogeneous disorder, and can be controlled by tuning the turbidity of the system. These results support the idea that the traditional dichotomy between normal and anomalous diffusion is reductive and that a richer framework should be constructed based on the concept of self-similarity as this class of transport regimes may be far more common that it is currently believed. In addition, this insight can help understand scenarios where transport is dominated by rare propagation events, as in non-linear and active media, or more generally in other fields of research.
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- 2023
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16. Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort
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Komodo Matta, Vivian Viallon, Edoardo Botteri, Giulia Peveri, Christina Dahm, Anne Østergaard Nannsen, Anja Olsen, Anne Tjønneland, Alexis Elbaz, Fanny Artaud, Chloé Marques, Rudolf Kaaks, Verena Katzke, Matthias B. Schulze, Erand Llanaj, Giovanna Masala, Valeria Pala, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Jeroen W. G. Derksen, Therese Haugdahl Nøst, Torkjel M. Sandanger, Kristin Benjaminsen Borch, J. Ramón Quirós, Carlota Castro-Espin, Maria-José Sánchez, Amaia Aizpurua Atxega, Lluís Cirera, Marcela Guevara, Jonas Manjer, Sandar Tin Tin, Alicia Heath, Mathilde Touvier, Marcel Goldberg, Elisabete Weiderpass, Marc J. Gunter, Heinz Freisling, Elio Riboli, and Pietro Ferrari
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Healthy lifestyle index ,Composite score ,Change score ,Mortality ,Cancer ,Longitudinal ,Medicine - Abstract
Abstract Background Healthy lifestyles are inversely associated with the risk of noncommunicable diseases, which are leading causes of death. However, few studies have used longitudinal data to assess the impact of changing lifestyle behaviours on all-cause and cancer mortality. Methods Within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, lifestyle profiles of 308,497 cancer-free adults (71% female) aged 35–70 years at recruitment across nine countries were assessed with baseline and follow-up questionnaires administered on average of 7 years apart. A healthy lifestyle index (HLI), assessed at two time points, combined information on smoking status, alcohol intake, body mass index, and physical activity, and ranged from 0 to 16 units. A change score was calculated as the difference between HLI at baseline and follow-up. Associations between HLI change and all-cause and cancer mortality were modelled with Cox regression, and the impact of changing HLI on accelerating mortality rate was estimated by rate advancement periods (RAP, in years). Results After the follow-up questionnaire, participants were followed for an average of 9.9 years, with 21,696 deaths (8407 cancer deaths) documented. Compared to participants whose HLIs remained stable (within one unit), improving HLI by more than one unit was inversely associated with all-cause and cancer mortality (hazard ratio [HR]: 0.84; 95% confidence interval [CI]: 0.81, 0.88; and HR: 0.87; 95% CI: 0.82, 0.92; respectively), while worsening HLI by more than one unit was associated with an increase in mortality (all-cause mortality HR: 1.26; 95% CI: 1.20, 1.33; cancer mortality HR: 1.19; 95% CI: 1.09, 1.29). Participants who worsened HLI by more than one advanced their risk of death by 1.62 (1.44, 1.96) years, while participants who improved HLI by the same amount delayed their risk of death by 1.19 (0.65, 2.32) years, compared to those with stable HLI. Conclusions Making healthier lifestyle changes during adulthood was inversely associated with all-cause and cancer mortality and delayed risk of death. Conversely, making unhealthier lifestyle changes was positively associated with mortality and an accelerated risk of death.
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- 2024
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17. Long-COVID autonomic syndrome in working age and work ability impairment
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Luca Rinaldi, Stefano Rigo, Margherita Pani, Andrea Bisoglio, Kareem Khalaf, Maura Minonzio, Dana Shiffer, Maria Angela Romeo, Paolo Verzeletti, Michele Ciccarelli, Maria Grazia Bordoni, Saverio Stranges, Elio Riboli, Raffaello Furlan, and Franca Barbic
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Medicine ,Science - Abstract
Abstract Long-COVID19 has been recently associated with long-sick leave and unemployment. The autonomic nervous system functioning may be also affected by SARS-CoV-2, leading to a chronic autonomic syndrome. This latter remains widely unrecognized in clinical practice. In the present study, we assessed the occurrence of Long-COVID19 Autonomic Syndrome in a group of active workers as well as the relationships between their autonomic dysfunction and work ability. This prospective observational study was conducted during the 2nd wave of the pandemic in Italy. Forty-five patients (53.6 ± 8.4 years; 32 M) hospitalized for COVID19, were consecutively enrolled at the time of their hospital discharge (T0) and followed-up for 6 months. Autonomic symptoms and work ability were assessed by COMPASS31 and Work Ability Index questionnaires at T0, one (T1), three and six (T6) months after hospital discharge and compared to those retrospectively collected for a period preceding SARS-CoV-2 infection. Clinical examination and standing test were also performed at T1 and T6. One in three working-age people developed a new autonomic syndrome that was still evident 6 months after the acute infection resolution. This was associated with a significant reduction in the work ability. Recognition of Long-COVID19 Autonomic Syndrome may promote early intervention to facilitate return to work and prevent unemployment.
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- 2024
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18. Prospective associations of leucocyte subtypes and obesity with the risk of developing cutaneous malignant melanoma in the UK Biobank cohort
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Sofia Christakoudi, Konstantinos K. Tsilidis, and Elio Riboli
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Neutrophils ,Monocytes ,Lymphocytes ,Abdominal obesity ,ABSI ,Obesity ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Obesity is associated with chronic low-grade inflammation, which is linked to cancer development. Abdominal obesity (a body mass index, ABSI), however, has unusually been associated inversely with cutaneous malignant melanoma (CMM), while general obesity (body mass index, BMI) is associated positively. Leucocytes participate in inflammation and are higher in obesity, but prospective associations of leucocytes with cutaneous malignant melanoma are unclear. Methods We examined the prospective associations of neutrophil, lymphocyte, and monocyte counts (each individually), as well as the prospective associations of ABSI and BMI, with cutaneous malignant melanoma in UK Biobank. We used multivariable Cox proportional hazards models and explored heterogeneity according to sex, menopausal status, age (≥ 50 years at recruitment), smoking status, ABSI (dichotomised at the median: ≥73.5 women; ≥79.8 men), BMI (normal weight, overweight, obese), and time to diagnosis. Results During a mean follow-up of 10.2 years, 2174 CMM cases were ascertained in 398,450 participants. There was little evidence for associations with neutrophil or lymphocyte counts. Monocyte count, however, was associated inversely in participants overall (HR = 0.928; 95%CI: 0.888–0.971; per one standard deviation increase; SD = 0.144*109/L women; SD = 0.169*109/L men), specifically in older participants (HR = 0.906; 95%CI: 0.862–0.951), and more clearly in participants with low ABSI (HR = 0.880; 95%CI: 0.824–0.939), or with BMI ≥ 25 kg/m2 (HR = 0.895; 95%CI: 0.837–0.958 for overweight; HR = 0.923; 95%CI: 0.848–1.005 for obese). ABSI was associated inversely in pre-menopausal women (HR = 0.810; 95%CI: 0.702–0.935; SD = 4.95) and men (HR = 0.925; 95%CI: 0.867–0.986; SD = 4.11). BMI was associated positively in men (HR = 1.148; 95%CI: 1.078–1.222; SD = 4.04 kg/m2). There was little evidence for heterogeneity according to smoking status. The associations with monocyte count and BMI were retained to at least 8 years prior to diagnosis, but the association with ABSI was observed up to 4 years prior to diagnosis and not for longer follow-up time. Conclusions Monocyte count is associated prospectively inversely with the risk of developing CMM in older individuals, while BMI is associated positively in men, suggesting a mechanistic involvement of factors related to monocytes and subcutaneous adipose tissue in melanoma development. An inverse association with ABSI closer to diagnosis may reflect reverse causality or glucocorticoid resistance.
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- 2024
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19. Impact of pre‐existing cardiometabolic diseases on metastatic cancer stage at diagnosis: a prospective multinational cohort study
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Anna Jansana, Aviane Auguste, Marina Kvaskoff, Agnès Fournier, Emma Fontvieille, Laia Peruchet‐Noray, Carine Biessy, Reynalda Cordova, Kristina Elin Nielsen Petersen, Anne Tjønneland, Verena Katzke, Rudolf Kaaks, Fulvio Ricceri, Salvatore Panico, Paolo Contiero, Maria‐Jose Sánchez, Jesus Castilla, Marta Crous‐Bou, Alicia Heath, Elom Kouassivi Aglago, Elisabete Weiderpass, Marc James Gunter, Pietro Ferrari, Elio Riboli, Vivian Viallon, and Heinz Freisling
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2024
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20. Public libraries to promote public health and wellbeing: a cross-sectional study of community-dwelling adults
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Manisha Karki, Marie Line El Asmar, Eva Riboli Sasco, and Austen El-Osta
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Self-care ,Libraries ,Prevention ,Community development ,Public engagement ,Health ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Libraries in the UK have evolved from traditional book-lending institutions into dynamic community hubs, This study aims to explore the potential of libraries to act as community hubs to promote mental and physical health and wellbeing of community-dwelling adults, drawing on insights from both library users and library staff in England. Design A mixed-method, cross-sectional study using online survey and interviews with community-dwelling adults and library staff. Methods We collected data using a 14-item electronic survey and interviews with library users and staff to gauge perceptions. Descriptive statistics and thematic analysis were used to identify key trends and emergent themes. Results We included 605 respondents from the survey and interviewed 12 library users and staff. Libraries remain popular and are considered a ‘safe place by members of the community, regardless of their frequency of service usage irrespective of whether they are frequent users of services. However, a lack of awareness among library users about community-facing services could act as a hurdle to improving community health and wellbeing. Targeted engagement with residents is needed to increase awareness of libraries’ services, including community interventions to help tackle loneliness and inequalities in digital and health literacy. Library staff often did not feel involved in important decision-making. Various barriers, drivers and practical recommendations were identified to leverage libraries as hubs to promote community health and wellbeing. Conclusion Libraries already offer a variety of resources that directly or indirectly support the health and wellbeing of community-dwelling adults and young people. However, public awareness of these services is limited. As we navigate post-pandemic recovery, libraries can serve as platforms for community engagement, fostering resilience, mental health support and reducing social isolation. Recognising libraries’ untapped potential can lead to healthier communities and improved wellbeing.
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- 2024
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21. Physical Realization of a Hyper Unclonable Function
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Nocentini, Sara, Rührmair, Ulrich, Barni, Mauro, Wiersma, Diederik S., and Riboli, Francesco
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Materials Science ,Computer Science - Cryptography and Security ,Physics - Optics ,Quantum Physics - Abstract
Disordered photonic structures are promising materials for the realization of physical unclonable functions (PUF), physical objects that can overcome the limitations of conventional digital security methods and that enable cryptographic protocols immune against attacks by future quantum computers. One PUF limitation, so far, has been that their physical configuration is either fixed or can only be permanently modified, and hence allowing only one token per device. We show that it is possible to overcome this limitation by creating a reconfigurable structure made by light-transformable polymers, in which the physical structure of the unclonable function itself can be reversibly reconfigured. We term this novel concept Hyper PUF or HPUF in that it allows a large number of physical unclonable functions to co-exist simultaneously within one and the same device. The physical transformation of the structure is done all-optically in a reversible and spatially controlled fashion. Our novel technology provides a massive enhancement in security generating more complex keys containing a larger amount of information. At the same time, it allows for new applications, for example serving multiple clients on a single encryption device and the practical implementation of quantum secure authentication of data.
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- 2022
22. Return to Play
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Riboli, Andrea, Oliva Lozano, José M., editor, and Ardigò, Luca P., editor
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- 2024
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23. Circulating hormones and risk of gastric cancer by subsite in three cohort studies
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Sanikini, Harinakshi, Biessy, Carine, Rinaldi, Sabina, Navionis, Anne-Sophie, Gicquiau, Audrey, Keski-Rahkonen, Pekka, Kiss, Agneta, Weinstein, Stephanie J., Albanes, Demetrius, Agudo, Antonio, Jenab, Mazda, Riboli, Elio, Gunter, Marc J., Murphy, Gwen, and Cross, Amanda J.
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- 2023
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24. How Italians Transgress: A Survey on Rough Sexual Behaviors in a Sample of Italians
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Luca Daminato, Greta Riboli, Mattia Nese, Gianni Brighetti, Daniel Giunti, and Rosita Borlimi
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rough sex ,choking ,sex practices ,sexual intercourse ,erotic asphyxiation ,intercourse ,Psychology ,BF1-990 ,Special aspects of education ,LC8-6691 ,Medicine (General) ,R5-920 - Abstract
Surveys of the Italian population typically assess general sexual behaviors (e.g., oral, vaginal and anal intercourse). However, little is known about other sexual behavior such as rough sexual behaviors, choking and slapping. Thus, an online cross-sectional survey of 4618 Italian participants was conducted. In the past month, the most prevalent sexual behaviors were solo masturbation (93.6%), partner masturbation (80.0%), oral sex (71.4% received, 75.9% performed), penile–vaginal intercourse (75.7%) and anal intercourse (12.5% received, 7.1% performed). Regarding rough sexual behaviors, the most common behaviors performed were spanking (23.3% received, 55.5% performed), choking (13.2% receive, 60.0% performed), slapping (30.1% received, 20.9% performed) and name calling (44.5% received, 37.0% performed). Our results suggest a gender difference where men and transgender/non-binary individuals perform more rough sexual behaviors compared to women. Moreover, regarding the role of consent in behaviors such as choking and slapping, our results highlight the importance of sexual and affective education to implement sexual assertiveness. In conclusion, this study adds knowledge to the limited literature on this topic, especially with respect to the Italian population.
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- 2024
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25. Links between the genetic determinants of morning plasma cortisol and body shape: a two-sample Mendelian randomisation study
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Sofia Christakoudi, Alexandros-Georgios Asimakopoulos, Elio Riboli, and Konstantinos K. Tsilidis
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Cortisol ,Body shape ,Obesity ,Mendelian randomisation ,Medicine ,Science - Abstract
Abstract High cortisol production in Cushing’s syndrome leads to fat centralisation. The influence of modest cortisol variations on body shape, however, is less clear. We examined potentially causal associations between morning plasma cortisol and body shape and obesity with inverse-variance weighted random-effects models in a two-sample Mendelian randomisation analysis. We used publicly available summary statistics from the CORtisol NETwork (CORNET) consortium, UK Biobank, and the Genetic Investigation of Anthropometric Traits (GIANT) consortium. Only in women, morning plasma cortisol (proxied by ten genetic polymorphisms) was associated positively with waist size reflected in waist-to-hip index (WHI, 0.035 standard deviation (SD) units change per one SD cortisol increase; 95% confidence interval (0.002–0.067); p = 0.036) and “a body shape index” (ABSI; 0.039 (0.006–0.071); p = 0.021). There was no evidence for associations with hip index (HI) or body mass index (BMI). Among individual polymorphisms, rs7450600 stood out (chromosome 6; Long Intergenic Non-Protein-Coding RNA 473 gene, LINC00473). Morning plasma cortisol proxied by rs7450600 was associated positively with WHI and inversely with HI and BMI in women and men. Our findings support a causal association of higher morning plasma cortisol with larger waist size in women and highlight LINC00473 as a genetic link between morning plasma cortisol and body shape.
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- 2024
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26. Quantifying the Sensitivity and Unclonability of Optical Physical Unclonable Functions
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Lio, Giuseppe Emanuele, Nocentini, Sara, Pattelli, Lorenzo, Cara, Eleonora, Wiersma, Diederik Sybolt, Rührmair, Ulrich, and Riboli, Francesco
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Computer Science - Cryptography and Security ,Physics - Applied Physics ,Physics - Optics - Abstract
Due to their unmatched entropy, complexity, and security level, optical Physical Unclonable Functions (PUFs) currently receive a lot of interest in the literature. Despite the large body of existing works, however, one of their core features has never been quantified in detail, namely their physical unclonability. This paper tackles this fundamental and yet largely unaddressed issue. In simulations and/or experiments, the sensitivity of diffraction-based optical responses is investigated with respect to various small alterations such as variation in the position, size, and number of the scatterers, as well as perturbations in the spatial alignment between the physical unclonable function (PUF) and the measurement apparatus. Our analysis focuses on 2D optical PUFs because of their relevance in integrated applications and the need to reply to security concerns that can be raised when the physical structure of the geometry is accessible. Among the results of this study, the sensitivity analysis shows that a positional perturbation of scatterers on the order of \SI{30}{\nano\meter}, i.e., far below the wavelength of the probing laser light of \SI{632}{\nano\meter} wavelength, is sufficient to invalidate the PUF response and thus detect a forgery attempt. These results support and quantify the high adversarial efforts required to clone optical PUFs, even for 2D layouts., Comment: 8 pages, 7 figures and Supporting Information
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- 2022
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27. Non-self-similar light transport in scattering media
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Ernesto Pini, Giacomo Mazzamuto, Francesco Riboli, Diederik S. Wiersma, and Lorenzo Pattelli
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Physics ,QC1-999 - Abstract
Transport processes underpin a wide variety of phenomena, ranging from chemistry, to physics and ecology. Despite their pervasiveness, however, several distinctive features of these processes are still elusive, making it difficult to recognize and classify the associated transport regimes. Using light scattering as a probe to explore different propagation regimes, we report on the experimental observation of non-self-similar light transport through turbid membranes. Our results show that a breakdown of self-similarity can arise for light waves even in the presence of isotropic and homogeneous disorder, and can be tuned by varying the turbidity of the system. By introducing the concept of self-similarity for light propagation, we provide a unified framework for the classification of light transport regimes—overcoming the dichotomy between normal and anomalous diffusion—and show that non-self-similar propagation is a common and experimentally accessible phenomenon. This insight can help to understand and model other scenarios where light transport is dominated by rare propagation events, such as in nonlinear and active media, but also in other fields of research beyond optics.
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- 2024
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28. A General Approach for Planning a Smooth Planar Path Within a Channel Using NURBS.
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Marco Riboli, Elisabetta Manconi, Rinaldo Garziera, and Alessandra Aimi
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- 2024
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29. Adiposity and metabolic health in Asian populations: an epidemiological study using dual-energy x-ray absorptiometry in Singapore
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Mina, Theresia, Xie, Wubin, Low, Dorrain Yanwen, Wang, Xiaoyan, Lam, Benjamin Chih Chiang, Sadhu, Nilanjana, Ng, Hong Kiat, Aziz, Nur-Azizah, Tong, Terry Yoke Yin, Kerk, Swat Kim, Choo, Wee Lin, Low, Guo Liang, Ibrahim, Halimah, Lim, Liming, Tai, E Shyong, Wansaicheong, Gervais, Dalan, Rinkoo, Yew, Yik Weng, Elliott, Paul, Riboli, Elio, Loh, Marie, Ngeow, Joanne, Lee, Eng Sing, Lee, Jimmy, Best, James, and Chambers, John
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- 2024
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30. General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants
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Zhou, Bin, Bennett, James E, Wickham, Aidan P, Singleton, Rosie K, Mishra, Anu, Carrillo-Larco, Rodrigo M, Ikeda, Nayu, Jain, Lakshya, Barradas-Pires, Ana, Heap, Rachel A, Lhoste, Victor PF, Sheffer, Kate E, Phelps, Nowell H, Rayner, Archie W, Gregg, Edward W, Woodward, Mark, Stevens, Gretchen A, Iurilli, Maria LC, Danaei, Goodarz, Di Cesare, Mariachiara, Aguilar-Salinas, Carlos A, Ahmad, Noor Ani, Bovet, Pascal, Chen, Zhengming, Damasceno, Albertino, Filippi, Sarah L, Janszky, Imre, Kengne, Andre P, Khang, Young-Ho, Khunti, Kamlesh, Laxmaiah, Avula, Lim, Lee-Ling, Lissner, Lauren, Margozzini, Paula, Mbanya, Jean Claude N, McGarvey, Stephen T, Shaw, Jonathan E, Söderberg, Stefan, Soto-Mota, Luis Adrián, Wang, Junyang, Zaccardi, Francesco, Abarca-Gómez, Leandra, Abbasi-Kangevari, Mohsen, Abdrakhmanova, Shynar, Abdul Ghaffar, Suhaila, Abdul Rahim, Hanan F, Abdurrahmonova, Zulfiya, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adam, Ishag, Adamczyk, Marzena, Aekplakorn, Wichai, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmed, Soheir H, Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M, Al-Hinai, Halima, Al-Lawati, Jawad A, Al-Raddadi, Rajaa, Al Asfoor, Deena, Al Hourani, Huda M, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alieva, Anna V, Alkandari, Abdullah, Alkhatib, Buthaina M, Aly, Eman, Amarapurkar, Deepak N, Amiano Etxezarreta, Pilar, Amougou, Norbert, Andersen, Lars Bo, Anderssen, Sigmund A, Androutsos, Odysseas, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Anufrieva, Elena, Aounallah-Skhiri, Hajer, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Assah, Felix K, Assembekov, Batyrbek, Assunção, Maria Cecília F, Auvinen, Juha, Avdičová, Mária, Azad, Kishwar, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Bacopoulou, Flora, Bahijri, Suhad, Bajramovic, Izet, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Baran, Rafał, Barbagallo, Carlo M, Barbosa Filho, Valter, Barceló, Alberto, Baretić, Maja, Barnoya, Joaquin, Barrera, Lena, Barros, Aluisio JD, Barros, Mauro Virgílio Gomes, Basit, Abdul, Bastos, Joao Luiz, Batieha, Anwar M, Batista, Aline P, Batista, Rosangela L, Battakova, Zhamilya, Baur, Louise A, Bayauli, Pascal M, Bel-Serrat, Silvia, Belavendra, Antonisamy, Ben Romdhane, Habiba, Benedek, Theodora, Benedics, Judith, Benet, Mikhail, Benitez Rolandi, Gilda Estela, Benzeval, Michaela, Bere, Elling, Berger, Nicolas, Bergh, Ingunn Holden, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bettiol, Heloísa, Beybey, Augustin F, Bezerra, Jorge, Bhagyalaxmi, Aroor, Bhargava, Santosh K, Bika Lele, Elysée Claude, Bikbov, Mukharram M, Bista, Bihungum, Bjelica, Dusko J, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B, Björkelund, Cecilia, Bloch, Katia V, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boddy, Lynne M, Boehm, Bernhard O, Boggia, Jose G, Bogova, Elena, Bonaccio, Marialaura, Bonilla-Vargas, Alice, Borghs, Herman, Botomba, Steve, Bourne, Rupert, Boymatova, Khadichamo, Braeckman, Lutgart, Braithwaite, Tasanee, Brajkovich, Imperia, Branca, Francesco, Brenner, Hermann, Brewster, Lizzy M, Briceño, Yajaira, Brinduse, Lacramioara, Bringolf-Isler, Bettina, Brito, Miguel, Brug, Johannes, Bugge, Anna, Buntinx, Frank, Buoncristiano, Marta, Burns, Con, Cabrera de León, Antonio, Caixeta, Roberta B, Cama, Tilema, Can, Günay, Cândido, Ana Paula C, Cañete, Felicia, Capanzana, Mario V, Čapková, Naděžda, Capuano, Eduardo, Capuano, Rocco, Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C, Casanueva, Felipe F, Casas, Maribel, Censi, Laura, Cervantes‐Loaiza, Marvin, Chamnan, Parinya, Chamukuttan, Snehalatha, Chan, Queenie, Chaturvedi, Nish, Chen, Fangfang, Chen, Huashuai, Chen, Long-Sheng, Cheng, Yiling J, Cheraghian, Bahman, Chetrit, Angela, Chikova-Iscener, Ekaterina, Chinapaw, Mai JM, Chinnock, Anne, Chiolero, Arnaud, Chirita-Emandi, Adela, Chirlaque, María-Dolores, Chong, Chean Lin, Christofaro, Diego G, Chudek, Jerzy, Cifkova, Renata, Cirillo, Massimo, Claessens, Frank, Clare, Philip, Cohen, Emmanuel, Confortin, Susana C, Coppinger, Tara C, Cortés, Lilia Yadira, Cosmin, Cojocaru R, Costanzo, Simona, Cowan, Melanie J, Cowell, Chris, Crampin, Amelia C, Cross, Amanda J, Crujeiras, Ana B, Cruz, Juan J, Cucu, Alexandra M, Cureau, Felipe V, Cuschieri, Sarah, D'Arrigo, Graziella, d'Orsi, Eleonora, da Silva-Ferreira, Haroldo, Dahm, Christina C, Dallongeville, Jean, Dankner, Rachel, Davletov, Kairat, de Assis Guedes de Vasconcelos, Francisco, de Assis, Maria Alice Altenburg, De Bacquer, Dirk, De Bacquer, Jaco, de Bont, Jeroen, De Curtis, Amalia, de Fragas Hinnig, Patrícia, de Gaetano, Giovanni, De Henauw, Stefaan, De Miguel-Etayo, Pilar, de Oliveira, Paula Duarte, de Paiva, Karina Mary, De Ridder, Karin, de Valois Correia Júnior, Marco Aurélio, Deepa, Mohan, DeGennaro, Vincent Jr, Demarest, Stefaan, Dennison, Elaine, Deschamps, Valérie, Dhimal, Meghnath, Díez Ripollés, María Pilar, Dika, Zivka, Djalalinia, Shirin, Dominguez, Liria, Donati, Maria Benedetta, Donfrancesco, Chiara, Dong, Guanghui, Donoso, Silvana P, Dorobantu, Maria, Dörr, Marcus, Dragano, Nico, Drygas, Wojciech, Du, Shufa, Duante, Charmaine A, Duboz, Priscilla, Duda, Rosemary B, Duleva, Vesselka L, Dushpanova, Anar, Dyussupova, Azhar, Dziankowska-Zaborszczyk, Elzbieta, Ebrahimi, Narges, Echeverría, Guadalupe, Eddie, Ricky, Eftekhar, Ebrahim, Efthymiou, Vasiliki, Egbagbe, Eruke E, Eghtesad, Sareh, Ekelund, Ulf, El-Khateeb, Mohammad, El Ati, Jalila, Elosua, Roberto, Enang, Ofem, Erasmus, Rajiv T, Erem, Cihangir, Ergor, Gul, Eriksen, Louise, Eriksson, Johan G, Escobedo-de la Peña, Jorge, Esmaeili, Ali, Evans, Roger G, Fakhradiyev, Ildar, Fakhretdinova, Albina A, Fall, Caroline H, Faramarzi, Elnaz, Farjam, Mojtaba, Farzadfar, Farshad, Farzi, Yosef, Fattahi, Mohammad Reza, Fawwad, Asher, Felix-Redondo, Francisco J, Ferguson, Trevor S, Fernandes, Romulo A, Fernández-Bergés, Daniel, Fernando, Desha R, Ferrante, Daniel, Ferrari, Gerson, Ferrari, Marika, Ferreccio, Catterina, Ferrer, Eldridge, Figueiró, Thamara Hubler, Fijalkowska, Anna, Fink, Günther, Fisberg, Mauro, Forsner, Maria, Fottrell, Edward F, Fouad, Heba M, Francis, Damian K, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Furdela, Viktoriya, Furusawa, Takuro, Gabriela, Stefan Adela, Gaciong, Zbigniew, Galán Cuesta, Manuel, Galbarczyk, Andrzej, Galcheva, Sonya V, Galfo, Myriam, Garcia-de-la-Hera, Manoli, Garcia, Pablo, Garnett, Sarah P, Gasull, Magda, Gazzinelli, Andrea, Gehring, Ulrike, Gerdts, Eva, Ghaderi, Ebrahim, Ghamari, Seyyed-Hadi, Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Ghimire, Anup, Gialluisi, Alessandro, Giampaoli, Simona, Gianfagna, Francesco, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantinos, Glushkova, Natalya, Godara, Ramesh, Godos, Justyna, Goldberg, Marcel, Gómez, Georgina, Gómez Gómez, Jesús Humberto, Gomez, Luis F, Gómez, Santiago F, Gomula, Aleksandra, Gonçalves Cordeiro da Silva, Bruna, Gonçalves, Helen, Gonçalves, Mauer, González-Alvarez, Ana D, Gonzalez-Chica, David A, González-Gil, Esther M, Gonzalez-Gross, Marcela, González-Rivas, Juan P, Gonzalez, Angel R, Gottrand, Frederic, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G, Grodzicki, Tomasz, Grøholt, Else Karin, Grøntved, Anders, Guajardo, Viviana, Guallar-Castillón, Pilar, Guerchet, Maëlenn, Guerrero, Ramiro, Guimaraes, Andre L, Gujral, Unjali P, Gulliford, Martin C, Gunter, Marc J, Gupta, Rajeev, Gureje, Oye, Gurinović, Mirjana A, Gurzkowska, Beata, Gutierrez, Laura, Gwee, Xinyi, Haghshenas, Rosa, Hakimi, Hamid, Halkjær, Jytte, Hambleton, Ian R, Hamzeh, Behrooz, Hanekom, Willem A, Hange, Dominique, Hanif, Abu AM, Hantunen, Sari, Hao, Jie, Hardman, Carla Menêses, Hardy, Louise, Hari Kumar, Rachakulla, Harooni, Javad, Hashemi-Shahri, Seyed Mohammad, Hassapidou, Maria, Hata, Jun, Haugsgjerd, Teresa, Heinen, Mirjam, Hendriks, Marleen Elisabeth, Henrique, Rafael dos Santos, Henriques, Ana, Hernandez Cadena, Leticia, Herrala, Sauli, Herrera-Cuenca, Marianella, Herrera, Victor M, Herter-Aeberli, Isabelle, Herzig, Karl-Heinz, Heshmat, Ramin, Hill, Allan G, Ho, Sai Yin, Holdsworth, Michelle, Homayounfar, Reza, Homs, Clara, Hoogendijk, Emiel O, Horimoto, Andrea RVR, Hormiga, Claudia M, Horta, Bernardo L, Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Htike, Maung Maung Than, Huerta, José María, Huhtaniemi, Ilpo Tapani, Huiart, Laetitia, Huidumac Petrescu, Constanta, Huisman, Martijn, Husseini, Abdullatif, Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iakupova, Ellina M, Iannone, Anna G, Igland, Jannicke, Ijoma, Chinwuba, Iotova, Violeta, Irazola, Vilma E, Ishida, Takafumi, Isiguzo, Godsent C, Islam, Muhammad, Islam, Sheikh Mohammed Shariful, Islek, Duygu, Ittermann, Till, Ivanova-Pandourska, Ivaila Y, Iwasaki, Masanori, Jääskeläinen, Tuija, Jackson, Rod T, Jaddou, Hashem Y, Jadoul, Michel, Jafar, Tazeen, Jan, Nataša, Janus, Edward, Jarani, Juel, Jarnig, Gerald, Jarvelin, Marjo-Riitta, Jasienska, Grazyna, Jelaković, Ana, Jelaković, Bojan, Jha, Anjani Kumar, Jimenez, Ramon O, Jöckel, Karl-Heinz, Joffres, Michel, Jokelainen, Jari J, Jonas, Jost B, Joshi, Pradeep, Joshi, Rohina, Josipović, Josipa, Joukar, Farahnaz, Jóźwiak, Jacek J, Juolevi, Anne, Juresa, Vesna, Jureša, Vesna, Kaaks, Rudolf, Kaducu, Felix O, Kadvan, Agnes L, Kafatos, Anthony, Kajantie, Eero O, Kakutia, Natia, Kállayová, Daniela, Kalmatayeva, Zhanna, Kalter-Leibovici, Ofra, Kannan, Srinivasan, Kapantais, Efthymios, Karaglani, Eva, Karakosta, Argyro, Karki, Khem B, Kassi Anicet, Adoubi, Katibeh, Marzieh, Katulanda, Prasad, Katzmarzyk, Peter T, Kauhanen, Jussi, Kazakbaeva, Gyulli M, Kaze, François F, Ke, Calvin, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kelleher, Cecily, Kemper, Han CG, Keramati, Maryam, Kersting, Mathilde, Khader, Yousef Saleh, Khaledifar, Arsalan, Khalili, Davood, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Kiechl-Kohlendorfer, Ursula, Kiechl, Sophia J, Kiechl, Stefan, Kim, Hyeon Chang, Klakk, Heidi, Klanarong, Suntara, Klanova, Jana, Klimek, Magdalena, Knoflach, Michael, Kobel, Susanne, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, König, Jürgen, Korpelainen, Raija, Korrovits, Paul, Korzycka, Magdalena, Kos, Jelena, Koskinen, Seppo, Koussoh Simone, Malik, Kovács, Éva, Kovalskys, Irina, Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kratzer, Wolfgang, Kriemler, Susi, Kristensen, Peter Lund, Krizan, Helena, Kroker-Lobos, Maria F, Krokstad, Steinar, Kruger, Herculina S, Kruger, Ruan, Kryst, Łukasz, Kubinova, Ruzena, Kujala, Urho M, Kujundzic, Enisa, Kulaga, Zbigniew, Kulimbet, Mukhtar, Kumari, Meena, Kunešová, Marie, Kurjata, Pawel, Kyobutungi, Catherine, La, Quang Ngoc, Labadarios, Demetre, Lachat, Carl, Lai, Daphne, Laid, Youcef, Lall, Lachmie, Landaeta Jimenez, Maritza, Landais, Edwige, Lankila, Tiina, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Lateva, Mina P, Latt, Tint Swe, Laurenzi, Martino, Lazo-Porras, Maria, Le Coroller, Gwenaëlle, Le Nguyen Bao, Khanh, Lehtimäki, Terho, Lemogoum, Daniel, Leong, Elvynna, Leszczak, Justyna, Leung, Gabriel M, Li, Yanping, Liivak, Merike, Lim, Charlie, Lim, Wei-Yen, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lind, Lars, Litwin, Mieczyslaw, Liu, Liping, Liu, Xiaotian, Longo Abril, Guadalupe, Lopes, Oscar, Lopez-Garcia, Esther, López-Gil, José Francisco, Lopez, Tania, Lozano, José Eugenio, Lukrafka, Janice L, Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lunogelo, Charles, Lustigová, Michala, M'Buyamba-Kabangu, Jean-René, Machado-Coelho, George LL, Machado-Rodrigues, Aristides M, Macia, Enguerran, Madar, Ahmed A, Maestre, Gladys E, Maggi, Stefania, Magliano, Dianna J, Magnacca, Sara, Magriplis, Emmanuella, Mahasampath, Gowri, Maire, Bernard, Makdisse, Marcia, Malekpour, Mohammad-Reza, Malekzadeh, Fatemeh, Malekzadeh, Reza, Mallikharjuna Rao, Kodavanti, Malyutina, Sofia, Maniego, Lynell V, Manios, Yannis, Mann, Jim I, Mansour-Ghanaei, Fariborz, Manzato, Enzo, Mapatano, Mala Ali, Maria-Magdalena, Rosu, Mariño, Joany, Markaki, Anastasia, Marques, Larissa Pruner, Marrugat, Jaume, Martorell, Reynaldo, Maruszczak, Katharina, Masala, Giovanna, Mascarenhas, Luis P, Masimango Imani, Mannix, Masinaei, Masoud, Mathiesen, Ellisiv B, Matijasevich, Alicia, Matłosz, Piotr, Matsha, Tandi E, Matsudo, Victor, Matteo, Giletta, Maulik, Pallab K, Mavrogianni, Christina, Mc Donald Posso, Anselmo J, McFarlane, Shelly R, McLean, Rachael M, Mediene Benchekor, Sounnia, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Melgarejo, Jesus D, Méndez, Fabián, Mendivil, Carlos O, Mendoza Montano, Carlos, Menezes, Ana Maria B, Mensink, Gert BM, Mereke, Alibek, Meshram, Indrapal I, Meto, Diane T, Meyer, Haakon E, Mi, Jie, Miłkowska, Karolina, Miller, Jody C, Milushkina, Olga, Minderico, Cláudia S, Mini, GK, Miquel, Juan Francisco, Miranda, J Jaime, Mirjalili, Mohammad Reza, Mišigoj-Duraković, Marjeta, Mistretta, Antonio, Mocanu, Veronica, Modesti, Pietro A, Moghaddam, Sahar Saeedi, Mohammad, Kazem, Mohammadi, Mohammad Reza, Mohammadi, Zahra, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohan, Viswanathan, Mohd Yusoff, Muhammad Fadhli, Mohebbi, Iraj, Møller, Niels C, Molnár, Dénes, Momenan, Amirabbas, Mondo, Charles K, Monroy-Valle, Michele M, Montenegro Mendoza, Roger A, Monterrubio-Flores, Eric, Monyeki, Kotsedi Daniel K, Moon, Jin Soo, Moosazadeh, Mahmood, Moradpour, Farhad, Moreira, Leila B, Morejon, Alain, Moreno, Luis A, Morgan, Karen, Moschonis, George, Moslem, Alireza, Mosquera, Mildrey, Mossakowska, Malgorzata, Mostafa, Aya, Mostafavi, Seyed-Ali, Motlagh, Mohammad Esmaeel, Motta, Jorge, Moura-dos-Santos, Marcos André, Mridha, Malay K, Msyamboza, Kelias P, Mu, Thet Thet, Muca, Florian, Mugoša, Boban, Munroe, Patricia B, Mursu, Jaakko, Musa, Kamarul Imran, Musić Milanović, Sanja, Musil, Vera, Musinguzi, Geofrey, Mustafa, Norlaila, Muyer, Muel Telo Marie-Claire, Nabipour, Iraj, Naidu, Balkish M, Najafi, Farid, Nalecz, Hanna, Námešná, Jana, Narayan, KM Venkat, Naseri, Take, Nathalie, Michels, Neelapaichit, Nareemarn, Nejatizadeh, Azim, Nenko, Ilona, Nervi, Flavio, Neuhauser, Hannelore K, Ng, Tze Pin, Nguyen, Chung T, Nguyen, Quang V, Nguyen, Quang Ngoc, Ni, Michael Y, Nie, Peng, Nieto-Martínez, Ramfis E, Niiranen, Teemu J, Ninomiya, Toshiharu, Nishi, Nobuo, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A, Nogueira, Helena, Norton, Kevin I, Noto, Davide, Nowak-Szczepanska, Natalia, Nsour, Mohannad Al, Nuhoğlu, Irfan, Nurk, Eha, Nuwaha, Fred, Nyirenda, Moffat, O'Neill, Terence W, Ochimana, Caleb, Ochoa-Avilés, Angélica M, Oda, Eiji, Odili, Augustine N, Oh, Kyungwon, Ohtsuka, Ryutaro, Oldenburg, Brian, Olié, Valérie, Omar, Mohd Azahadi, Omar, Saeed M, Onat, Altan, Ong, Sok King, Onland-Moret, N Charlotte, Ono, Lariane M, Onodugo, Obinna, Ordunez, Pedro, Ornelas, Rui, Ortiz, Ana P, Ortiz, Pedro J, Osmond, Clive, Ostojic, Sergej M, Ostovar, Afshin, Otero, Johanna A, Ottendahl, Charlotte B, Otu, Akaninyene, Overvad, Kim, Owusu-Dabo, Ellis, Padez, Cristina P, Pagkalos, Ioannis, Pajula, Natalja, Palloni, Alberto, Palmieri, Luigi, Pan, Wen-Harn, Panza, Francesco, Paoli, Mariela, Papadopoulou, Sousana K, Pareja, Rossina G, Park, Soon-Woo, Park, Suyeon, Parnell, Winsome R, Parsaeian, Mahboubeh, Pascanu, Ionela M, Pasquet, Patrick, Patel, Nikhil D, Pavlyshyn, Halyna, Pechlaner, Raimund, Pećin, Ivan, Pedro, João M, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C, Peres, Karen GDA, Peres, Marco A, Perez-Londoño, Agustín, Pérez, Cynthia M, Peterkova, Valentina, Petrovna Kovtun, Olga, Peykari, Niloofar, Pham, Son Thai, Pichardo, Rafael N, Pierre-Marie, Preux, Pikhart, Hynek, Pilav, Aida, Piler, Pavel, Piwonska, Aleksandra, Pizarro, Andreia N, Plata, Silvia, Pop, Raluca M, Popkin, Barry M, Popovic, Stevo R, Porta, Miquel, Poudyal, Anil, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J, Prista, Antonio, Providencia, Rui, Puder, Jardena J, Pudule, Iveta, Puhakka, Soile, Puiu, Maria, Punab, Margus, Qorbani, Mostafa, Quialheiro, Anna, Quintana, Hedley K, Quiroga-Padilla, Pedro J, Quoc Bao, Tran, Rach, Stefan, Rahimikazerooni, Salar, Rahman, Mahmudur, Raitakari, Olli, Rakhmatulloev, Sherali, Rakovac, Ivo, Ramachandran, Ambady, Ramadan, Otim PC, Ramirez-Zea, Manuel, Ramos, Rafel, Rampal, Lekhraj, Rampal, Sanjay, Ramsay, Sheena E, Rangel Junior, João FLB, Rangel Reina, Daniel A, Rangelova, Lalka S, Rarra, Vayia, Rashidi, Mohammad-Mahdi, Rech, Cassiano Ricardo, Redon, Josep, Regecová, Valéria, Renner, Jane DP, Repasy, Judit A, Reuter, Cézane P, Revilla, Luis, Reynolds, Andrew, Rezaei, Negar, Rezaianzadeh, Abbas, Riboli, Elio, Rigo, Fernando, Rigotti, Attilio, Riley, Leanne M, Rinke de Wit, Tobias F, Risérus, Ulf, Ritti-Dias, Raphael M, Roa, Reina G, Roccaldo, Romana, Rodríguez-Artalejo, Fernando, Rodriguez-Perez, María del Cristo, Rodríguez-Villamizar, Laura A, Rodríguez, Andrea Y, Roggenbuck, Ulla, Rohloff, Peter, Rojas-Martinez, Rosalba, Romeo, Elisabetta L, Rosario, Rafaela V, Rosengren, Annika, Rouse, Ian, Rubinstein, Adolfo, Ruiz-Betancourt, Blanca Sandra, Ruiz-Castell, Maria, Ruiz Moreno, Emma, Rusakova, Iuliia A, Rusek, Wojciech, Rust, Petra, Rutkowski, Marcin, Saamel, Marge, Sabbaghi, Hamideh, Sachdev, Harshpal S, Sadjadi, Alireza, Safarpour, Ali Reza, Safi, Sare, Saghi, Mohammad Hossien, Saidi, Olfa, Saieva, Calogero, Sakata, Satoko, Saki, Nader, Šalaj, Sanja, Salazar Martinez, Eduardo, Salkhanova, Akkumis, Salonen, Jukka T, Samoutian, Margarita, Sánchez-Abanto, Jose, Sánchez Rodríguez, Inés, Santos, Diana A, Santos, Ina S, Santos, Maria Paula, Santos, Tamara R, Saramies, Jouko L, Sardinha, Luis B, Sarganas, Giselle, Sarrafzadegan, Nizal, Saum, Kai-Uwe, Savin, Stefan, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D, Schienkiewitz, Anja, Schindler, Karin, Schipf, Sabine, Schmidt, Amand Floriaan, Schmidt, Börge, Schmidt, Carsten O, Schöttker, Ben, Schramm, Sara, Schramm, Stine, Schröder, Helmut, Schultsz, Constance, Schutte, Aletta E, Sebert, Sylvain, Sedaghattalab, Moslem, Sein, Aye Aye, Sen, Abhijit, Sepanlou, Sadaf G, Sequera, Guillermo, Ševčíková, Ľudmila, Sewpaul, Ronel, Shamah-Levy, Teresa, Shamshirgaran, Seyed Morteza, Sharafkhah, Maryam, Sharma, Sanjib K, Sharman, Almaz, Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shiri, Rahman, Shoranov, Marat, Shrestha, Namuna, Si-Ramlee, Khairil, Sibai, Abla M, Sidossis, Labros S, Silva, Antonio M, Silva, Caroline Ramos de Moura, Silva, Diego Augusto Santos, Silva, Kelly Samara, Sim, Xueling, Simon, Mary, Sjöström, Michael, Skoblina, Natalia A, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemysław, Smeeth, Liam, Smith, Lee, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugène, Sodemann, Morten, Soemantri, Agustinus, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sørgjerd, Elin P, Sorić, Maroje, Soto-Rojas, Victoria E, Soumaré, Aïcha, Sousa-Poza, Alfonso, Spiroski, Igor, Staessen, Jan A, Stang, Andreas, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Sturua, Lela, Suarez-Ortegón, Milton F, Suebsamran, Phalakorn, Sulo, Gerhard, Sundström, Johan, Suriyawongpaisal, Paibul, Swinburn, Boyd A, Sylva, René Charles, Szponar, Lucjan, Tai, E Shyong, Tambalis, Konstantinos D, Tamosiunas, Abdonas, Tanabayev, Baimakhan, Tanrygulyyeva, Maya, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B, Taxová Braunerová, Radka, Te Velde, Saskia, Tebar, William R, Tell, Grethe S, Tello, Tania, Thankappan, KR, Theodoridis, Xenophon, Thirunavukkarasu, Sathish, Thomas, Nihal, Thrift, Amanda G, Tichá, Ľubica, Timmermans, Erik J, Tjandrarini, Dwi Hapsari, Tjonneland, Anne, Tolstrup, Janne S, Topbas, Murat, Torres-Collado, Laura, Touloumi, Giota, Traissac, Pierre, Triantafyllou, Areti, Trivedi, Atul, Tshepo, Lechaba, Tsintavis, Panagiotis, Tuitele, John, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Turley, Maria L, Tzala, Evangelia, Tzotzas, Themistoklis, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ukoli, Flora AM, Usupova, Zhamyila, Uusitalo, Hannu MT, Uysal, Nalan, Valdivia, Gonzalo, Valvi, Damaskini, van Dam, Rob M, van den Born, Bert-Jan, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Lippevelde, Wendy, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Varela-Moreiras, Gregorio, Vargas, Luz Nayibe, Vasan, Senthil K, Vasques, Daniel G, Vega, Tomas, Velasquez-Melendez, Gustavo, Velika, Biruta, Verdot, Charlotte, Verloigne, Maïté, Veronesi, Giovanni, Verschuren, WM Monique, Verstraeten, Roosmarijn, Viet, Lucie, Vik, Frøydis N, Vilar, Monica, Villalpando, Salvador, Vioque, Jesus, Virtanen, Jyrki K, Visser, Marjolein, Viswanathan, Bharathi, Vladulescu, Mihaela, Völzke, Henry, Voutilainen, Ari, Vrijheid, Martine, Wade, Alisha N, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley Júnior, Rildo de Souza, Wang, Chongjian, Wang, Huijun, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nicholas, Wartha, Olivia, Weber, Adelheid, Webster-Kerr, Karen, Wedderkopp, Niels, Weghuber, Daniel, Wei, Wenbin, Westbury, Leo, Whincup, Peter H, Wickramasinghe, Kremlin, Widhalm, Kurt, Widyahening, Indah S, Więcek, Andrzej, Wilks, Rainford J, Willeit, Karin, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Andrew, Wong, Emily B, Wu, Frederick C, Wyszyńska, Justyna, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yan, Li, Yan, Weili, Yang, Yang, Yépez García, Martha, Yoosefi, Moein, Yoshihara, Akihiro, Younger-Coleman, Novie O, Yu, Yu-Ling, Yu, Yunjiang, Yusoff, Ahmad Faudzi, Zafiropulos, Vassilis, Zainuddin, Ahmad A, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Zapata, Maria Elisa, Zaw, Ko Ko, Zdrojewski, Tomasz, Żegleń, Magdalena, Zejglicova, Kristyna, Zeljkovic Vrkic, Tajana, Zhang, Bing, Zhang, Zhen-Yu, Zhecheva, Yanitsa V, Zholdin, Bekbolat, Zimmet, Paul, Zins, Marie, Zuñiga Cisneros, Julio, Zuziak, Monika, and Ezzati, Majid
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31. Exploring the link between self-management of migraine and emotional wellbeing: a cross-sectional study of community-dwelling migraine sufferers
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Nicola Filzmoser, Iman Webber, Gabriele Kerr, Aos Alaa, Marie Iine El Asmar, Manisha Karki, Eva Riboli-Sasco, and Austen El-Osta
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Migraine ,Self-care ,Lifestyle change ,Lifestyle medicine ,Self-management ,Headache ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Background Globally, an estimated 14% of adults live with migraine disease which impacts their physical, emotional and social wellbeing. To target the disease comprehensively, research recommends a multidisciplinary approach to migraine management. Yet, at present, migraine management primarily centers around pharmaceutical treatments. The aim of this study was to investigate the extent to which emotional awareness could influence the uptake of self-care behaviours of community-dwelling adults with migraine. Methods A cross-sectional online survey explored personal experiences with migraine disease and strategies or behaviours to manage migraine attacks. Chi-squared tests were used to investigate differences in ratings of migraine prevention and management strategies between users and non-users of the strategies. Univariable logistic regressions were used to assess the effectiveness of self-care behaviours to manage or prevent migraine attacks. Results We surveyed 170 community-dwelling adults with migraine in the United Kingdom, Austria, Germany and the United States. Most (85%) respondents had experienced migraine for over five years, where 42% of attacks usually lasted several days. Whereas we did not differentiate between diagnosis by a neurologist or self-diagnosis, the most common diagnoses in the cohort were migraine without aura (38.9%) and migraine with aura (29%). Staying hydrated was the most popular preventative strategy (87%), 70.2% used prescription medication and 64.9% changed their diet and/or supplements. Almost all ( 92.4%) respondents stated that their mood or emotions could trigger their migraine attacks. Keeping a headache or mood diary was the lowest-rated prevention strategy and was rated as "probably ineffective" or causing "no change" in preventing migraine attacks. Over a third (39.7%) kept track of their physical wellbeing and symptoms. Reasons stated for tracking symptoms included to identify triggers (65.8%), show reports to a healthcare professional (59.6%), understand when they must take medication (48.1%), track improvements (67.3%) or deteriorations (67.3%). Conclusions Migraine management is dominated by pharmaceutical management for acute pain attacks and lifestyle changes for managing migraine long-term. Perception of the effectiveness of those techniques is high, whereas perception of interventions that target the emotional or psychological components of chronic pain management (keeping a mood diary, and mental health support) is mixed. There exists a gap between the recommended biopsychosocial approach and the current state of migraine management. Graphical Abstract
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- 2024
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32. Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
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Yew, Yik Weng, Mina, Theresia, Ng, Hong Kiat, Lam, Benjamin Chih Chiang, Riboli, Elio, Lee, Eng Sing, Lee, Jimmy, Ngeow, Joanne, Elliott, Paul, Thng, Steven Tien Guan, Chambers, John C., and Loh, Marie
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- 2023
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33. Diet and lifestyle in relation to small intestinal cancer risk: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)
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Ersoy Guller, Zeynep, Harewood, Rhea N., Weiderpass, Elisabete, Huybrechts, Inge, Jenab, Mazda, Huerta, José María, Sánchez, Maria-Jose, Jakszyn, Paula, Amiano, Pilar, Ardanaz, Eva, Agnoli, Claudia, Tumino, Rosario, Palli, Domenico, Skeie, Guri, Manjer, Jonas, Papier, Keren, Tjønneland, Anne, Eriksen, Anne Kirstine, Schulze, Matthias B., Kaaks, Rudolf, Katzke, Verena, Bergmann, Manuela M., Riboli, Elio, Gunter, Marc J., and Cross, Amanda J.
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- 2023
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34. A new approach to comparing the demands of small-sided games and soccer matches
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Mauro Mandorino, Antonio Tessitore, Sebastien Coustou, Andrea Riboli, and Mathieu Lacome
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euclidean distance ,performance ,external load ,overload ,similarity ,Sports medicine ,RC1200-1245 ,Biology (General) ,QH301-705.5 - Abstract
To improve soccer performance, coaches should be able to replicate the match’s physical efforts during the training sessions. For this goal, small-sided games (SSGs) are widely used. The main purpose of the current study was to develop similarity and overload scores to quantify the degree of similarity and the extent to which the SSG was able to replicate match intensity. GPSs were employed to collect external load and were grouped in three vectors (kinematic, metabolic, and mechanical). Euclidean distance was used to calculate the distance between training and match vectors, which was subsequently converted into a similarity score. The average of the pairwise difference between vectors was used to develop the overload scores. Three similarity (Sim kin , Sim met , Sim mec ) and three overload scores (OVER kin , OVER met , OVER mec ) were defined for kinematic, metabolic, and mechanical vectors. Sim met and OVER met were excluded from further analysis, showing a very large correlation ( r > 0.7, p < 0.01) with Sim kin and OVER kin . The scores were subsequently analysed considering teams’ level (First team vs. U19 team) and SSGs’ characteristics in the various playing roles. The independentsample t -test showed ( p < 0.01) that the First team presented greater Sim kin ( d = 0.91), OVER kin ( d = 0.47), and OVER mec ( d = 0.35) scores. Moreover, a generalized linear mixed model (GLMM) was employed to evaluate differences according to SSG characteristics. The results suggest that a specific SSG format could lead to different similarity and overload scores according to the playing position. This process could simplify data interpretation and categorize SSGs based on their scores.
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- 2023
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35. Embedding work coaches in GP practices: Findings from an interview-based study in the UK
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Pattani, Shriti, El Asmar, Marie Line, Karki, Manisha, Sasco, Eva Riboli, Shemtob, Lara, Varghese, Kabir, and El-Osta, Austen
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- 2024
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36. Cryopreservation of canine ovarian tissue by slow freezing and vitrification: Evaluation of follicular morphology and apoptosis rate
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Luizari Stábile, Nicole A., Oliveira, Frederico Rocha de, Furtado, Ricardo Andrade, Felippe, Carolina Barretto M.L., Tavares, Mariana Riboli, Martinelli, Paulo E.B., Fonseca-Alves, Carlos Eduardo, Souza, Fabiana Ferreira de, Colombo, Martina, Luvoni, Gaia Cecilia, and Apparício, Maricy
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- 2024
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37. Anaerobic valorization of sewage sludge pretreated through hydrothermal carbonization: Volatile fatty acids and biomethane production
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Grana, Matteo, Riboli, Giorgia, Tatangelo, Valeria, Mantovani, Marco, Gandolfi, Isabella, Turolla, Andrea, and Ficara, Elena
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- 2024
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38. Interactions of platelets with obesity in relation to lung cancer risk in the UK Biobank cohort
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Christakoudi, Sofia, Tsilidis, Konstantinos K., Evangelou, Evangelos, and Riboli, Elio
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- 2023
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39. Associations of obesity and body shape with erythrocyte and reticulocyte parameters in the UK Biobank cohort
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Christakoudi, Sofia, Tsilidis, Konstantinos K., Evangelou, Evangelos, and Riboli, Elio
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- 2023
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40. Lipopolysaccharide-binding protein and future Parkinson’s disease risk: a European prospective cohort
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Zhao, Yujia, Walker, Douglas I., Lill, Christina M., Bloem, Bastiaan R., Darweesh, Sirwan K. L., Pinto-Pacheco, Brismar, McNeil, Brooklyn, Miller, Gary W., Heath, Alicia K., Frissen, Myrthe, Petrova, Dafina, Sánchez, Maria-Jose, Chirlaque, María-Dolores, Guevara, Marcela, Zibetti, Maurizio, Panico, Salvatore, Middleton, Lefkos, Katzke, Verena, Kaaks, Rudolf, Riboli, Elio, Masala, Giovanna, Sieri, Sabina, Zamora-Ros, Raul, Amiano, Pilar, Jenab, Mazda, Peters, Susan, and Vermeulen, Roel
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- 2023
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41. Experience and severity of menopause symptoms and effects on health-seeking behaviours: a cross-sectional online survey of community dwelling adults in the United Kingdom
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Huang, David Roy, Goodship, Abigail, Webber, Iman, Alaa, Aos, Sasco, Eva Riboli, Hayhoe, Benedict, and El-Osta, Austen
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- 2023
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42. A body shape index (ABSI) is associated inversely with post-menopausal progesterone-receptor-negative breast cancer risk in a large European cohort
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Christakoudi, Sofia, Tsilidis, Konstantinos K., Dossus, Laure, Rinaldi, Sabina, Weiderpass, Elisabete, Antoniussen, Christian S., Dahm, Christina C., Tjønneland, Anne, Mellemkjær, Lene, Katzke, Verena, Kaaks, Rudolf, Schulze, Matthias B., Masala, Giovanna, Grioni, Sara, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, May, Anne M., Monninkhof, Evelyn M., Quirós, J. Ramón, Bonet, Catalina, Sánchez, Maria-Jose, Amiano, Pilar, Chirlaque, María-Dolores, Guevara, Marcela, Rosendahl, Ann H., Stocks, Tanja, Perez-Cornago, Aurora, Tin Tin, Sandar, Heath, Alicia K., Aglago, Elom K., Peruchet-Noray, Laia, Freisling, Heinz, and Riboli, Elio
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- 2023
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43. Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition
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Yammine, S. G., Huybrechts, I., Biessy, C., Dossus, L., Panico, S., Sánchez, M. J., Benetou, V., Turzanski-Fortner, R., Katzke, V., Idahl, A., Skeie, G., Olsen, K. Standahl, Tjønneland, A., Halkjaer, J., Colorado-Yohar, S., Heath, A. K., Sonestedt, E., Sartor, H., Schulze, M. B., Palli, D., Crous-Bou, M., Dorronsoro, A., Overvad, K., Gurrea, A. Barricarte, Severi, G., Vermeulen, R. C.H., Sandanger, T. M., Travis, R. C., Key, T., Amiano, P., Van Guelpen, B., Johansson, M., Sund, M., Tumino, R., Wareham, N., Sacerdote, C., Krogh, V., Brennan, P., Riboli, E., Weiderpass, E., Gunter, M. J., and Chajès, V.
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- 2023
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44. Investigating self-reported efficacy of lifestyle medicine approaches to tackle erectile dysfunction: a cross-sectional eSurvey based study
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El-Osta, Austen, Kerr, Gabriele, Alaa, Aos, El Asmar, Marie Line, Karki, Manisha, Webber, Iman, Riboli Sasco, Eva, Blume, Giordano, Beecken, Wolf-D., and Mummery, David
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- 2023
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45. Sex differences in the associations of body size and body shape with platelets in the UK Biobank cohort
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Christakoudi, Sofia, Tsilidis, Konstantinos K., Evangelou, Evangelos, and Riboli, Elio
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- 2023
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46. Interactions of obesity, body shape, diabetes and sex steroids with respect to prostate cancer risk in the UK Biobank cohort
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Sofia Christakoudi, Konstantinos K. Tsilidis, Evangelos Evangelou, and Elio Riboli
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cancer prevention ,cancer risk factors ,epidemiology ,prostate cancer ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Obesity and diabetes are associated inversely with low‐grade prostate cancer risk and affect steroid hormone synthesis but whether they modify each other's impact on prostate cancer risk remains unknown. Methods We examined the independent associations of diabetes, body mass index (BMI), ‘a body shape index’ (ABSI), hip index (HI), circulating testosterone, sex hormone binding globulin (SHBG) (per one standard deviation increase) and oestradiol ≥175 pmol/L with total prostate cancer risk using multivariable Cox proportional hazards models for UK Biobank men. We evaluated multiplicative interactions (pMI) and additive interactions (relative excess risk from interaction (pRERI), attributable proportion (pAR), synergy index (pSI)) with obese (BMI ≥30 kg/m2) and diabetes. Results During a mean follow‐up of 10.3 years, 9417 incident prostate cancers were diagnosed in 195,813 men. Diabetes and BMI were associated more strongly inversely with prostate cancer risk when occurring together (pMI = 0.0003, pRERI = 0.032, pAP = 0.020, pSI = 0.002). ABSI was associated positively in obese men (HR = 1.081; 95% CI = 1.030–1.135) and men with diabetes (HR = 1.114; 95% CI = 1.021–1.216). The inverse associations with obesity and diabetes were attenuated for high‐ABSI ≥79.8 (pMI = 0.022, pRERI = 0.008, pAP = 0.005, pSI
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- 2024
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47. Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysisResearch in context
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James Yarmolinsky, Jamie W. Robinson, Daniela Mariosa, Ville Karhunen, Jian Huang, Niki Dimou, Neil Murphy, Kimberley Burrows, Emmanouil Bouras, Karl Smith-Byrne, Sarah J. Lewis, Tessel E. Galesloot, Lambertus A. Kiemeney, Sita Vermeulen, Paul Martin, Demetrius Albanes, Lifang Hou, Polly A. Newcomb, Emily White, Alicja Wolk, Anna H. Wu, Loïc Le Marchand, Amanda I. Phipps, Daniel D. Buchanan, Sizheng Steven Zhao, Dipender Gill, Stephen J. Chanock, Mark P. Purdue, George Davey Smith, Paul Brennan, Karl-Heinz Herzig, Marjo-Riitta Järvelin, Chris I. Amos, Rayjean J. Hung, Abbas Dehghan, Mattias Johansson, Marc J. Gunter, Kostas K. Tsilidis, Richard M. Martin, Maria Teresa Landi, Victoria Stevens, Ying Wang, Demetrios Albanes, Neil Caporaso, Christopher I. Amos, Sanjay Shete, Heike Bickeböller, Angela Risch, Richard Houlston, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, H-Erich Wichmann, David Christiani, Gadi Rennert, Susanne Arnold, John K. Field, Loic Le Marchand, Olle Melander, Hans Brunnström, Geoffrey Liu, Angeline Andrew, Hongbing Shen, Shan Zienolddiny, Kjell Grankvist, Mikael Johansson, M. Dawn Teare, Yun-Chul Hong, Jian-Min Yuan, Philip Lazarus, Matthew B. Schabath, Melinda C. Aldrich, Rosalind A. Eeles, Christopher A. Haiman, Zsofia Kote-Jarai, Fredrick R. Schumacher, Sara Benlloch, Ali Amin Al Olama, Kenneth R. Muir, Sonja I. Berndt, David V. Conti, Fredrik Wiklund, Stephen Chanock, Catherine M. Tangen, Jyotsna Batra, Judith A. Clements, Henrik Grönberg, Nora Pashayan, Johanna Schleutker, Stephanie J. Weinstein, Catharine M.L. West, Lorelei A. Mucci, Géraldine Cancel-Tassin, Stella Koutros, Karina Dalsgaard Sørensen, Eli Marie Grindedal, David E. Neal, Freddie C. Hamdy, Jenny L. Donovan, Ruth C. Travis, Robert J. Hamilton, Sue Ann Ingles, Barry S. Rosenstein, Yong-Jie Lu, Graham G. Giles, Robert J. MacInnis, Adam S. Kibel, Ana Vega, Manolis Kogevinas, Kathryn L. Penney, Jong Y. Park, Janet L. Stanfrod, Cezary Cybulski, Børge G. Nordestgaard, Sune F. Nielsen, Hermann Brenner, Christiane Maier, Christopher J. Logothetis, Esther M. John, Manuel R. Teixeira, Susan L. Neuhausen, Kim De Ruyck, Azad Razack, Lisa F. Newcomb, Davor Lessel, Radka Kaneva, Nawaid Usmani, Frank Claessens, Paul A. Townsend, Jose Esteban Castelao, Monique J. Roobol, Florence Menegaux, Kay-Tee Khaw, Lisa Cannon-Albright, Hardev Pandha, Stephen N. Thibodeau, David J. Hunter, Peter Kraft, William J. Blot, and Elio Riboli
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Inflammation ,Cancer ,Mendelian randomization ,Genetic epidemiology ,Medicine ,Medicine (General) ,R5-920 - Abstract
Summary: Background: Tumour-promoting inflammation is a “hallmark” of cancer and conventional epidemiological studies have reported links between various inflammatory markers and cancer risk. The causal nature of these relationships and, thus, the suitability of these markers as intervention targets for cancer prevention is unclear. Methods: We meta-analysed 6 genome-wide association studies of circulating inflammatory markers comprising 59,969 participants of European ancestry. We then used combined cis-Mendelian randomization and colocalisation analysis to evaluate the causal role of 66 circulating inflammatory markers in risk of 30 adult cancers in 338,294 cancer cases and up to 1,238,345 controls. Genetic instruments for inflammatory markers were constructed using genome-wide significant (P 70% was employed to indicate support for shared causal variants across inflammatory markers and cancer outcomes. Findings were replicated in the FinnGen study and then pooled using meta-analysis. Findings: We found strong evidence to support an association of genetically-proxied circulating pro-adrenomedullin concentrations with increased breast cancer risk (OR: 1.19, 95% CI: 1.10–1.29, q-value = 0.033, PPH4 = 84.3%) and suggestive evidence to support associations of interleukin-23 receptor concentrations with increased pancreatic cancer risk (OR: 1.42, 95% CI: 1.20–1.69, q-value = 0.055, PPH4 = 73.9%), prothrombin concentrations with decreased basal cell carcinoma risk (OR: 0.66, 95% CI: 0.53–0.81, q-value = 0.067, PPH4 = 81.8%), and interleukin-1 receptor-like 1 concentrations with decreased triple-negative breast cancer risk (OR: 0.92, 95% CI: 0.88–0.97, q-value = 0.15, PPH4 = 85.6%). These findings were replicated in pooled analyses with the FinnGen study. Though suggestive evidence was found to support an association of macrophage migration inhibitory factor concentrations with increased bladder cancer risk (OR: 2.46, 95% CI: 1.48–4.10, q-value = 0.072, PPH4 = 76.1%), this finding was not replicated when pooled with the FinnGen study. For 22 of 30 cancer outcomes examined, there was little evidence (q-value ≥0.20) that any of the 66 circulating inflammatory markers examined were associated with cancer risk. Interpretation: Our comprehensive joint Mendelian randomization and colocalisation analysis of the role of circulating inflammatory markers in cancer risk identified potential roles for 4 circulating inflammatory markers in risk of 4 site-specific cancers. Contrary to reports from some prior conventional epidemiological studies, we found little evidence of association of circulating inflammatory markers with the majority of site-specific cancers evaluated. Funding: Cancer Research UK (C68933/A28534, C18281/A29019, PPRCPJT∖100005), World Cancer Research Fund (IIG_FULL_2020_022), National Institute for Health Research (NIHR202411, BRC-1215-20011), Medical Research Council (MC_UU_00011/1, MC_UU_00011/3, MC_UU_00011/6, and MC_UU_00011/4), Academy of Finland Project 326291, European Union's Horizon 2020 grant agreement no. 848158 (EarlyCause), French National Cancer Institute (INCa SHSESP20, 2020-076), Versus Arthritis (21173, 21754, 21755), National Institutes of Health (U19 CA203654), National Cancer Institute (U19CA203654).
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- 2024
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48. Interactions of platelets with obesity in relation to lung cancer risk in the UK Biobank cohort
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Sofia Christakoudi, Konstantinos K. Tsilidis, Evangelos Evangelou, and Elio Riboli
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Platelet count ,MPV ,PDW ,Obesity ,Interaction ,Lung cancer ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background Platelet count (PLT) is associated positively with lung cancer risk but has a more complex association with body mass index (BMI), positive only in women (mainly never smokers) and inverse in men (mainly ever smokers), raising the question whether platelets interact with obesity in relation to lung cancer risk. Prospective associations of platelet size (an index of platelet maturity and activity) with lung cancer risk are unclear. Methods We examined the associations of PLT, mean platelet volume (MPV), and platelet distribution width (PDW) (each individually, per one standard deviation increase) with lung cancer risk in UK Biobank men and women using multivariable Cox proportional hazards models adjusted for BMI and covariates. We calculated Relative Excess Risk from Interaction (RERI) with obese (BMI ≥ 30 kg/m2), dichotomising platelet parameters at ≥ median (sex-specific), and multiplicative interactions with BMI (continuous scale). We examined heterogeneity according to smoking status (never, former, current smoker) and antiaggregant/anticoagulant use (no/yes). Results During a mean follow-up of 10.4 years, 1620 lung cancers were ascertained in 192,355 men and 1495 lung cancers in 218,761 women. PLT was associated positively with lung cancer risk in men (hazard ratio HR = 1.14; 95% confidence interval (CI): 1.09–1.20) and women (HR = 1.09; 95%CI: 1.03–1.15) but interacted inversely with BMI only in men (RERI = − 0.53; 95%CI: − 0.80 to − 0.26 for high-PLT-obese; HR = 0.92; 95%CI = 0.88–0.96 for PLT*BMI). Only in men, MPV was associated inversely with lung cancer risk (HR = 0.95; 95%CI: 0.90–0.99) and interacted positively with BMI (RERI = 0.27; 95%CI = 0.09–0.45 for high-MPV-obese; HR = 1.08; 95%CI = 1.04–1.13 for MPV*BMI), while PDW was associated positively (HR = 1.05; 95%CI: 1.00–1.10), with no evidence for interactions. The associations with PLT were consistent by smoking status, but MPV was associated inversely only in current smokers and PDW positively only in never/former smokers. The interactions with BMI were retained for at least eight years of follow-up and were consistent by smoking status but were attenuated in antiaggregant/anticoagulant users. Conclusions In men, PLT was associated positively and MPV inversely with lung cancer risk and these associations appeared hindered by obesity. In women, only PLT was associated positively, with little evidence for interaction with obesity.
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- 2023
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49. Vibration Minimisation of Moving Flexible Slender Structures Based on Time-Parameterised B-Spline
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Marco Riboli, Elisabetta Manconi, Dario Fusai, Marco Silvestri, and Alessandra Aimi
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joint trajectory planning ,vibration reduction ,B-spline curves ,quadratic programming ,flexible slender structures ,Physics ,QC1-999 - Abstract
Vibration mitigation of moving flexible structures is a key issue in many applications. Examples include antennas, solar arrays, radar reflectors, and manipulator arms, especially in the aerospace sector. These structures typically consist of inter-connected slender and flexible elements moved by external actuators to reach specific configurations and positions. The movements excite vibrations, which lead to the risk of structural and fatigue failures; once in position, residual vibrations can be further amplified by structure lightness, causing bad performance and malfunctioning of onboard sensors. This paper proposes an effective technique to minimise the vibration of moving flexible structures by calculating the control points of a time-parametrised B-spline representing the shape of the motion law. A testing case of a rotating cantilever beam is considered. Validation using multi-flexible-body simulation software has shown the method’s effectiveness in minimising residual vibrations.
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- 2023
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50. Top-class women’s soccer performance: peak demands and distribution of the match activities relative to maximal intensities during official matches
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Andreas Riboli, Lorenzo Francini, Emanuele Rossi, Andrea Caronti, Lorenzo Boldrini, and Stefano Mazzoni
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team sports ,football ,training load ,coaching ,high intensity training ,Sports medicine ,RC1200-1245 ,Biology (General) ,QH301-705.5 - Abstract
The aims of the current study were to determine the most demanding passages of match play (MDP) and the distribution of match activities relative to maximum intensities during official matches in topclass women soccer players. Twenty-eight women players competing in European championship and international UEFA competitions were monitored during 38 official matches (277 individual samples). Maximum relative (m·min −1 ) total distance (TD), high-speed running (HSRD), very high-speed running (VHSRD), sprint, acceleration and deceleration distances were calculated across different durations (1–5, 10, 15, 90 min) using a rolling average analysis. Maximum intensities (1-min peak ) were used as the reference value to determine the distribution of relative intensity across the whole-match demands (90-min avg ). Time and distance higher than 90-min avg (> 90-min avg ) were also calculated. MDP showed moderate to very large [effect size (ES): 0.63/5.20] differences between 1-min peak vs all durations for each parameter. The relative (m ·min −1 ) 1-min peak was greater than 90-min avg of about +63% for TD, +358% for HSRD, +969% for VHSRD, +2785% for sprint, +1216% for acceleration, and +768% for deceleration. The total distance covered > 90-min avg was ~66.6% of the total distance covered during the 90-min avg for TD, ~84.8% for HSRD, ~97.4% for VHSRD, ~100% for sprint, ~99.1% for acceleration and ~98.2% for deceleration. The relative distance > 90-min avg was higher ( P < 0.05) than the 90-min avg for each metric (ES: 2.22 to 7.58; very large). The present results may help coaches and sport scientists to replicate the peak demands during training routine in top-class women soccer players.
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- 2023
- Full Text
- View/download PDF
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