Search

Giuliana Ribeiro de Carvalho,1,2 Vagner Loduca Lima,2 Glaucia Luciano da Veiga,1 Fernando Adami,3 Beatriz da Costa Aguiar Alves,1 Edimar Cristiano Pereira,4 David Feder,1 Fernando Luiz Affonso Fonseca1,4 1Clinical Analysis Laboratory, Centro Universitário Saúde ABC/Faculdade De Medicina Do ABC, Santo André, Brazil; 2Ophthalmology Discipline, Centro Universitário Saúde ABC-Faculdade de Medicina do ABC, Santo André, Brazil; 3Epidemiology Department, Centro Universitário Saúde ABC/Faculdade De Medicina Do ABC, Santo André, Brazil; 4Pharmaceutical Sciences Department, Universidade Federal De São Paulo, Diadema, BrazilCorrespondence: Fernando Luiz Affonso Fonseca 2000, Lauro Gomes Avenue, Santo Andre CEP: 09060-650, BrazilTel +5511 4993-5488Email profferfonseca@gmail.comIntroduction: Diabetes mellitus (DM) stands out as one of the chronic diseases with the highest morbidity and mortality rates worldwide. Among the many complications of DM, diabetic retinopathy (DR) is one of the causes of blindness in patients aged between 20 and 64 years. At least 90% of the new cases showed to have the retinal structure and function restored when proper treatment was provided.Aim: To evaluate the efficacy of the antiangiogenic bevacizumab in the treatment of DR according not only to the clinical laboratory parameters for glycated hemoglobin (HbA1C) and capillary glycemia but also to the ophthalmological parameters for optical coherence tomography (OCT) and best-corrected visual acuity (BCVA).Patients and Methods: A total of 11 individuals were included and followed up for 12 months after 3 administrations of bevacizumab.Results: Upon associating the ophthalmological and laboratory variables throughout the treatment, no significant alterations could be seen regarding the analyzed variables. However, it was observed that HbA1c values and the total leukocyte count negatively interfered with the treatment response.Conclusion: The current study showed that HbA1c values and the amount of leukocytes negatively interfere with the therapeutic response. Therefore, laboratory analyses of these parameters are recommended for diabetic patients undergoing the above-mentioned treatment.Keywords: diabetic retinopathy, bevacizumab, macular edema

O texto apresenta resultados de pesquisa sobre a relação do princípio pluralista com dimensões da ecoteologia. Metodologicamente, se recorreu a análises do pluralismo antropológico, em chave latino-americana, especialmente as que realçam a concepção do ser humano nas suas múltiplas relações com a natureza e o cosmo. Os resultados são apresentados em três eixos: (i) a busca de novos perfis epistemológicos tendo em vista a crítica às características antropocêntricas, androcêntricas e patriarcais da cultura ocidental assimiladas pela teologia, (ii) a noção do humano, em seus limites e possibilidades, em especial no tocante à relação com a Terra e o cosmo, à sua condição de coparticipante do contínuo ato criador divino e às possibilidades de relacionalidade e interdependência, e (iii) o poder renovador da vida como expressão de uma ecodiaconia, com indicações práticas de reconstrução ecossocial, dentro do cenário da destruição ambiental e da forma de ver a fé em perspectiva plural como maneira de ser na vida.

Background: Lately pollinators of the main crops have presented a decline with considerable economic impacts. Among the probable causes of this problem is the inadequate use of pesticides, mainly in monocultures. The culture of melon (Cucumis melo) is dependent on pollination services by honey bees (Apis mellifera L.). However, agrochemicals are not applied with special care to the visitation of bees in cultivated areas at the irrigation pole of Petrolina-Juazeiro, located in Brazilian Northeast. Therefore, the objective of this study was to evaluate the effect of agrochemicals pulverization on the pattern of visitation of honeybees to melon flowers. Results: In the dry season the honey bees’ visits occurred since 6 a.m. in larger numbers than in the wet season. Indeed, in the dry season, there was a negative effect of the application of agrochemicals on the frequency of visitation by A. mellifera, after the 1st, 2nd, and 5th day of pulverization. This effect was more intense on the 1st day, when there were registered average values smaller than one visit, independently of the flower type and time of the day. Moreover, the first visits were observed only from 8 a.m. On the 5th day the average numbers of visits were still lower than in the dry season, but higher than on the previous days.Conclusion: Comparing both seasons, we found that the frequency of visitation observed in wet season was lower than that found in dry season. This indicates that the productivity of the melon in the first period can be reduced by the excessive application of agrochemicals, since there will be a reduction of the pollination services.

In order to conduct a proper risk assessment of pesticides to bees, information is needed in three areas: (i) the toxicity of the pesticide; (ii) the probability of bee exposure to that pesticide; and (iii) the population dynamics of the bee species in question.Information was collected on such factors affecting pesticide risk to (primarily wild) bees in several crops in Brazil, Kenya and The Netherlands. These data were used to construct ‘risk profiles’ of pesticide use for bees in the studied cropping systems. Data gaps were identified and potential risks of pesticides to bees were compared between the crops.Initially, risk profiling aims to better identify gaps in our present knowledge. In the longer term, the established risk profiles may provide structured inputs into risk assessment models for wild and managed bees, and lead to recommendations for specific risk mitigation measures.

Tourism sector is based in services, most of them offered by small enterprises. The information and knowledge represents to this enterprises one of the main areas, used to define strategies and short/medium term business plans. This paper pretends to discuss the integrated knowledge management concept and present a new matrix developed during a Phd Thesis in Tourism at University of Aveiro (Portugal). The EGIC Matrix (Integrated Knowledge Management Spiral) is a new flexible methodology that can be used to analyse different destinations or even tourism market segments. Is a new concept of an integrated approach that can be very useful for public and private enterprises and tourism organizations. The authors used this matrix to study a market segment growing, residential tourism, thus proving its usefulness and added value achieved for the sector.

Palavras-chave: Empiema; Complicações Pós-Operatórias; Doenças Ureterais; Nefrectomia.