20 results on '"Ri-Ming Huang"'
Search Results
2. An Update on 2,5-Diketopiperazines from Marine Organisms
- Author
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Ri-Ming Huang, Xiang-Xi Yi, Yuying Zhou, Xiangdong Su, Yan Peng, and Cheng-Hai Gao
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2,5-diketopiperazine ,marine organism ,biosynthetic processes ,biological activity ,Biology (General) ,QH301-705.5 - Abstract
2,5-Diketopiperazines (2,5-DKPs) are an important category of structurally diverse cyclic dipeptides with prominent biological properties. These 2,5-DKPs have been obtained from a variety of natural resources, including marine organisms. Because of the increasing numbers and biological importance of these compounds, this review covers 90 marine originated 2,5-DKPs that were reported from 2009 to the first half-year of 2014. The review will focus on the structure characterizations, biological properties and proposed biosynthetic processes of these compounds.
- Published
- 2014
- Full Text
- View/download PDF
3. Marine Nucleosides: Structure, Bioactivity, Synthesis and Biosynthesis
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Ri-Ming Huang, Yin-Ning Chen, Ziyu Zeng, Cheng-Hai Gao, Xiangdong Su, and Yan Peng
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biological activity ,biosynthetic pathway ,marine organism ,nucleoside ,synthesis ,Biology (General) ,QH301-705.5 - Abstract
Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.
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- 2014
- Full Text
- View/download PDF
4. New Antioxidative Secondary Metabolites from the Fruits of a Beibu Gulf Mangrove, Avicennia marina
- Author
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Cheng-Hai Gao, Xiang-Xi Yi, Wen-Pei Xie, Yin-Ning Chen, Ming-Ben Xu, Zhi-Wei Su, Lian Yu, and Ri-Ming Huang
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antioxidant ,Avicennia marina ,caffeoyl glycoside ,marinoid ,phenylethyl glycoside ,Biology (General) ,QH301-705.5 - Abstract
Further chemical investigation of the fruits of the mangrove, Avicennia marina, afforded three new phenylethyl glycosides, marinoids J–L (1–3), and a new cinnamoyl glycoside, marinoid M (4). The structures of isolates were elucidated on the basis of extensive spectroscopic analysis and by comparison of the data with those of related secondary metabolites. The antioxidant activity of the isolates was evaluated using the cellular antioxidant assay (CAA), and compounds 1–4 showed antioxidant activities, with EC50 values ranging from 23.0 ± 0.71 μM to 247.8 ± 2.47 μM.
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- 2014
- Full Text
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5. Four New Jacaranone Analogs from the Fruits of a Beibu Gulf Mangrove Avicennia marina
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Xiang-Xi Yi, Yong Chen, Wen-Pei Xie, Ming-Ben Xu, Yin-Ning Chen, Cheng-Hai Gao, and Ri-Ming Huang
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antioxidant ,Avicennia marina ,chlorocornoside ,cornoside ,jacaranone analogs ,marinoid ,Biology (General) ,QH301-705.5 - Abstract
Four new jacaranone analogs, marinoids F–I (1–4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC50 = 26 μM).
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- 2014
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6. Nutritional Composition and Antioxidant Properties of the Fruits of a Chinese Wild Passiflora foetida
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Ya Song, Xiao-Qun Wei, Mei-Ying Li, Xue-Wu Duan, Yuan-Ming Sun, Rui-Li Yang, Xiang-Dong Su, Ri-Ming Huang, and Hong Wang
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Passiflora foetida ,fruit ,nutritional composition ,antioxidant properties ,UPLC-MS ,phenolic compound ,Organic chemistry ,QD241-441 - Abstract
The aim of this work was to evaluate the main nutrients and their antioxidant properties of a Chinese wild edible fruit, Passiflora foetida, collected from the ecoregion of Hainan province, China. The analytical results revealed that P. foetida fruits were rich in amino acids (1097 mg/100 g in total), minerals (595.75 mg/100 g in total), and unsaturated fatty acids (74.18 g/100 g in total fat). The lyophilized powder of edible portion contained the higher polyphenols content than the inedible portion powder. The UPLC-Q-TOF-MSE analysis of the extractable and non-extractable phenolics indicated the presence of 65 compounds including 39 free phenolics, 14 insoluble-glycoside-phenolics, and 22 insoluble-ester-phenolics. In addition, the non-extractable phenolics obtained by alkali hydrolysis showed significant antioxidant activities by/through DPPH and ABTS radical scavenging. These findings of P. foetida fruits, for the first time, suggest that these polyphenol-rich fruits may have potential nutraceutical efficacies.
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- 2018
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7. Norisoprenoids from the Brown Alga Sargassum naozhouense Tseng et Lu
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Yan Peng, Ri-Ming Huang, Xiu-Ping Lin, and Yong-Hong Liu
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brown alga ,Sargassum naozhouense ,norisoprenoids ,cyclopentene ,Organic chemistry ,QD241-441 - Abstract
A new C11-norisoprenoid derivative, sargassumone (1), has been isolated from Sargassum naozhouense together with six known norisoprenoids and a highly oxygenated cyclopentene: (2R,6S,8S,9S)-hexahydro-2,9-dihydroxy-4,4,8-trimethyl-6-acetyloxy-3(2H)-benzofuranone (2), (6S,8S,9R)-hexahydro-6,9-dihydroxy-4,4,8-trimethyl-2(2H)-benzofuranone (3), (6S,8S,9R)-hexahydro-6,9-dihydroxy-4,4,8-trimethyl-2(2H)-benzofuranone (4), loliolide (5), (+)-epiloliolide (6), spheciospongones A (7), and (+)-kjellmanianone (8). Compound 1 was identified on the basis of nuclear magnetic resonance (NMR) and mass spectrometry (MS) analysis, and the absolute stereochemistry was defined by NOESY spectroscopy, minimizing energy calculation, and circular dichroism (CD) spectra. The known compounds 2–8, isolated from S. naozhouense for the first time, were identified by comparison of their physical and spectroscopic data with those reported in the literature. Compound 6 was tested for its inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), antioxidant activity with 1,1-diphyl-2-picrylhydrazyl (DPPH) free radicals, and antimicrobial activity against resistant clinical isolates of Candida albicans, methicillin-resistant Staphylococcus aureus (MRSA), and Escherichia coli.
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- 2018
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8. A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species
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Shi-Hai Xu, Xianwen Yang, Kyung Jin Lee, Tunhai Xu, Xue-Feng Zhou, Wei Ma, Jun-De Dong, Ri-Ming Huang, and Yonghong Liu
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marine sponge ,Callyspongia sp. ,diazepine ,callysponine ,Organic chemistry ,QD241-441 - Abstract
A new 1,4-diazepine, callysponine (1), was isolated from a South China Sea Callyspongia sp. marine sponge, together with four known proline-based diketopiperazines: cyclo-(S-Pro-R-Leu) (2), cyclo-(S-Pro-R-Val) (3), cyclo-(S-Pro-R-Ala) (4), andcyclo-(S-Pro-R-Tyr) (5). The new structure was determined on the basis of NMR and MS analysis, and the absolute stereochemistry was defined by NOESY spectroscopy and optical rotation. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Callysponine (1) did not inhibit the growth of HepG2 (hepatoma carcinoma cell), A549 (lung carcinoma cell), and HeLa (cervical cancer cell) cell lines.
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- 2010
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9. Effects of Environmental Factors on Fungal Diversity and Composition in Coastal Sediments from Guangdong, China
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Ke-Yue Wu, Yong-Chun Liu, Li Mo, Zu-Wang Sun, Zhi-Ying Liu, Zi-Hui Chen, Ri-Ming Huang, and Xiaoyong Zhang
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History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2022
10. Noni (
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Ming-Yu, Jin, Xiao-Yong, Wu, Mei-Ying, Li, Xiao-Tong, Li, Ri-Ming, Huang, Yuan-Ming, Sun, and Zhen-Lin, Xu
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Mice ,Polysaccharides ,Fruit ,Dextran Sulfate ,NF-kappa B ,Animals ,Humans ,Morinda ,Inflammatory Bowel Diseases ,Gastrointestinal Microbiome - Abstract
Inflammatory bowel disease (IBD) is a disease characterized by intestinal inflammation with immune dysregulation and intestinal microecological imbalance. In a dextran sulfate sodium salt (DSS)-induced IBD mouse model, noni (
- Published
- 2021
11. Biodiversity and antifouling activity of fungi associated with two soft corals from the South China Sea
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Li-Mei Dong, Ri-Ming Huang, Yu Han, Xiaoyong Zhang, Stanley C.K. Lau, Huaiyou Wang, and Huili Hao
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China ,South china ,Biofouling ,Oceans and Seas ,Biodiversity ,Zoology ,Bugula neritina ,Biochemistry ,Microbiology ,Bryozoa ,03 medical and health sciences ,Microbial ecology ,Genetics ,Animals ,Molecular Biology ,Phylogeny ,030304 developmental biology ,Mucor ,0303 health sciences ,biology ,030306 microbiology ,Cladiella krempfi ,fungi ,Sarcophyton tortuosum ,Fungi ,General Medicine ,Anthozoa ,biology.organism_classification - Abstract
Bacteria in corals have been studied in detail in the past decades. However, the biodiversity and bioactivity of fungi in corals are still poorly understood. This study investigated the biodiversity and antifouling activity of fungi in soft corals Cladiella krempfi and Sarcophyton tortuosum from the South China Sea. A high diverse and abundant fungal community was found in the two soft corals. Furthermore, five isolates shared 83-95% similarity with their closest relatives, indicating that they might be novel species in genera Phaeoshaeria and Mucor. In addition, approximately 50% of the representative isolates exhibited distinct antifouling activity. In particular, isolates Fungal sp. SCAU132 and Fungal sp. SCAU133 displayed very strong antifouling activity against Bugula neritina, suggesting they can provide a potential resource for further investigation on isolation of novel antifouling metabolites. To our knowledge, this study is the first report to investigate the biodiversity and antifouling activity of fungi in C. krempfi and S. tortuosum.
- Published
- 2019
12. Chemical composition and immunostimulatory properties of green alga Caulerpa racemosa var peltata
- Author
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Yimian Cai, Xiaoyong Zhang, Manqin Fu, Meiying Li, Ru Yan, Huili Hao, Baolin He, Ri-Ming Huang, and Qiabiao Liu
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lcsh:Immunologic diseases. Allergy ,South china ,caulerpa racemosa var peltata ,raw264.7 ,Nutritional composition ,010401 analytical chemistry ,Immunology ,immunostimulatory activity ,04 agricultural and veterinary sciences ,Biology ,040401 food science ,01 natural sciences ,Caulerpa racemosa var. peltata ,lcsh:S1-972 ,0104 chemical sciences ,0404 agricultural biotechnology ,Botany ,chemical composition ,lcsh:Agriculture (General) ,lcsh:RC581-607 ,Agronomy and Crop Science ,Chemical composition ,Food Science - Abstract
This work aimed to evaluate the nutritional composition and immunostimulatory activity of an edible green alga Caulerpa racemosa var peltata collected from South China Sea. The results indicated that this alga contained the total carbohydrates (71.67%, DW), crude protein (11.39%, DW), and crude lipid (1.03%, DW), and was rich in taurine (7.71 mg/100 g, DW), essential amino acids (40.07%), monounsaturated fatty acids (25.72%), and polyunsaturated fatty acids (26.33%). Moreover, water extraction of this alga (WEC) increased NO, ROS, TNF-α, and IL-6 in a dose-dependent manner in RAW264.7 macrophage cells. Furthermore, WEC contained the total sugar (34.19 ± 0.46 mg/g), total protein (6.76 ± 0.32 mg/g), total phenolic (1.93 ± 0.04 mg/g), and total flavonoid (4.80 ± 0.10 mg/g). In addition, the MSn analysis of WEC indicated that the presence of 19 compounds. Thus, these findings suggest that this alga may have a potential nutraceutical value.
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- 2019
13. Marine Nucleosides: Structure, Bioactivity, Synthesis and Biosynthesis
- Author
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Ziyu Zeng, Xiangdong Su, Yan Peng, Cheng Hai Gao, Yin Ning Chen, and Ri Ming Huang
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synthesis ,Stereochemistry ,Pharmaceutical Science ,Marine Biology ,biological activity ,Review ,Biology ,nucleoside ,chemistry.chemical_compound ,Biological Factors ,Biosynthesis ,Drug Discovery ,Animals ,Humans ,Nucleotide ,marine organism ,Pharmacology, Toxicology and Pharmaceutics (miscellaneous) ,lcsh:QH301-705.5 ,chemistry.chemical_classification ,Nucleotides ,RNA ,Biological activity ,Nucleosides ,biosynthetic pathway ,Biochemistry ,chemistry ,lcsh:Biology (General) ,Nucleoside ,DNA - Abstract
Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.
- Published
- 2014
14. Two New Stilbenoids from Cajanus cajan
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Sheng-Xiang Qiu, Zhiwei Su, Man-Qin Fu, Ri-Ming Huang, Nenling Zhang, Ying-jie Hu, Jia-zhong Cai, and Yue-Hui Zhu
- Subjects
Cajanus ,biology ,Chemistry ,Cell culture ,Stereochemistry ,Moderate activity ,General Chemistry ,Stilbenoid ,Cancer cell lines ,biology.organism_classification ,Cytotoxicity ,In vitro - Abstract
Two new stilbenoids cajanotone and cajanamide A (1-2), together with another six known ones (3- 8) and four known dihydroflavones (9-12), have been isolated from the leaves of Cajanus cajan. Their structures were elucidated based on spectroscopic studies. A possible pathway to the new compounds 1 and 2 has been proposed. In vitro cytotoxicities of selected compounds against cancer cell lines HepG2, MCF-7 and A549 have been evaluated. Compounds 7 and 8 show strong cytotoxity against all the tested cell lines (with IC50 values in the range of 3.5 - 6.0 μM), and compounds 1 and 3 showed strong to moderate activity against the three cell lines.
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- 2012
15. Two new lignans from the stems of Schisandra bicolor
- Author
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Xiao-Fei Jiang, Zhiwei Su, Ri-Ming Huang, Huijuan Huang, Zhi-Fang Xu, Chuan-Rong Li, Nenling Zhang, Samuel X. Qiu, Yue-Hui Zhu, and Jianxiang Yang
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Pharmacology ,Circular dichroism ,Molecular Structure ,Plant Stems ,Stereochemistry ,Organic Chemistry ,Pharmaceutical Science ,Hep G2 Cells ,General Medicine ,Biology ,Lignans ,Analytical Chemistry ,Complementary and alternative medicine ,Carcinoma Cell ,Drug Discovery ,Humans ,Molecular Medicine ,Female ,Drug Screening Assays, Antitumor ,Schisandra bicolor ,Nuclear Magnetic Resonance, Biomolecular ,Human breast ,Two-dimensional nuclear magnetic resonance spectroscopy ,Schisandra - Abstract
Two new lignans, named zuihonins E (1) and F (2), were isolated from the stems of Schisandra bicolor Cheng var. tuberculata Law. The structures of the new lignans were elucidated on the basis of extensive spectroscopic analysis, including 1D, 2D NMR, and MS experiments, and their absolute stereochemistry was determined by circular dichroism spectrum. Compounds 1 and 2 did not inhibit the growth of hepatoma carcinoma cell (HepG2), lung carcinoma cell (A549), and human breast carcinoma (MCF-7) cell lines.
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- 2012
16. Two New Secondary Metabolites from Tephrosia purpurea
- Author
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Yin-Ning, Chen, Yan, Peng, Cheng-Hai, Gao, Tao, Yan, Zhi-Fang, Xu, Samuel X, Qius, Wen-Hao, Cao, Ligao, Deng, and Ri-Ming, Huang
- Subjects
Flavonoids ,Prenylation ,Molecular Structure ,Plant Extracts ,Tephrosia ,Secondary Metabolism ,Flavones - Abstract
Further investigation of Tephrosia purpurea led to the isolation of a new prenylated flavone, isoglabratephrin B (1) and a new 1,2-ethanedione benzofuran derivative, purpdione B (2). The structures of the new isolates were elucidated on the basis of extensive spectroscopic analysis.
- Published
- 2015
17. An update on 2,5-diketopiperazines from marine organisms
- Author
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Cheng Hai Gao, Ri Ming Huang, Xiang Xi Yi, Yan Peng, Yuying Zhou, and Xiangdong Su
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Marine biology ,Aquatic Organisms ,biosynthetic processes ,2,5-diketopiperazine ,Ecology ,Pharmaceutical Science ,Marine Biology ,biological activity ,Computational biology ,Diketopiperazines ,Dipeptides ,Review ,Biology ,lcsh:Biology (General) ,Biological property ,Drug Discovery ,Humans ,marine organism ,Pharmacology, Toxicology and Pharmaceutics (miscellaneous) ,lcsh:QH301-705.5 - Abstract
2,5-Diketopiperazines (2,5-DKPs) are an important category of structurally diverse cyclic dipeptides with prominent biological properties. These 2,5-DKPs have been obtained from a variety of natural resources, including marine organisms. Because of the increasing numbers and biological importance of these compounds, this review covers 90 marine originated 2,5-DKPs that were reported from 2009 to the first half-year of 2014. The review will focus on the structure characterizations, biological properties and proposed biosynthetic processes of these compounds.
- Published
- 2014
18. ChemInform Abstract: Two New Stilbenoids from Cajanus cajan
- Author
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Yue-Hui Zhu, Sheng-Xiang Qiu, Ri-Ming Huang, Nenling Zhang, Ying-jie Hu, Jia-zhong Cai, Zhiwei Su, and Man-Qin Fu
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chemistry.chemical_classification ,Cajanus ,biology ,Traditional medicine ,Chemistry ,General Medicine ,biology.organism_classification ,Flavones - Abstract
Cajanotone (I) and cajanamide A (II) are isolated from the leaves of title pea along with ten known stilbenoids and flavones.
- Published
- 2013
19. Preparation and study on performance of submicron nickel powder for multilayer chip positive temperature coefficient resistance
- Author
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Peng Su, Qiuyun Fu, Ri-Ming Huang, Yong Chen, Shuping Gong, and Zhiping Zheng
- Subjects
inorganic chemicals ,Materials science ,Nucleation ,General Physics and Astronomy ,chemistry.chemical_element ,law.invention ,Nickel ,Optical microscope ,chemistry ,Chemical engineering ,law ,visual_art ,Electrode ,otorhinolaryngologic diseases ,visual_art.visual_art_medium ,Ceramic ,Temperature coefficient ,Base metal ,Sheet resistance - Abstract
Base metal nickel is often used as the inner electrode in multilayer chip positive temperature coefficient resistance (PTCR). The fine grain of ceramic powders and base metal nickel are necessary. This paper uses reducing hydrazine to gain submicron nickel powder whose diameter was 200–300 nm through adjusting the consumption of nucleating agent PVP properly. The submicron nickel powder could disperse well and was fit for co—fired of multilayer chip PTCR. It analyes the submicron nickel powder through x-ray Diffraction (XRD) and calculates the diameter of nickel by PDF cards. Using XRD analyses it obtains several conclusions: If the molar ratio of hydrazine hydrate and nickel sulfate is kept to be a constant, when enlarging the molar ratio of NaOH/Ni2+, the diameter of nickel powder would become smaller. When the temperature in the experiment raises to 70–80 °C, nickel powder becomes smaller too. And if the molar ratio of NaOH/Ni2+ is 4, when molar ratio of (C2H5O)2/Ni2+ increases, the diameter of nickel would reduce. Results from viewing the powders by optical microscope should be the fact that the electrode made by submicron nickel powder has a better formation and compactness. Furthermore, the sheet resistance testing shows that the electrode made by submicron nickel is smaller than that made by micron nickel.
- Published
- 2010
20. A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species.
- Author
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Ri-Ming Huang, Wei Ma, Jun-De Dong, Xue-Feng Zhou, Tunhai Xu, Kyung Jin Lee, Xianwen Yang, Shi-Hai Xu, and Yonghong Liu
- Subjects
- *
DIAZEPINES , *SPONGES (Invertebrates) , *OPTICAL rotation , *NUCLEAR spectroscopy , *STEREOCHEMISTRY - Abstract
A new 1,4-diazepine, callysponine (1), was isolated from a South China Sea Callyspongia sp. marine sponge, together with four known proline-based diketopiperazines: cyclo-(S-Pro-R-Leu) (2), cyclo-(S-Pro-R-Val) (3), cyclo-(S-Pro-R-Ala) (4), and cyclo-(SPro- R-Tyr) (5). The new structure was determined on the basis of NMR and MS analysis, and the absolute stereochemistry was defined by NOESY spectroscopy and optical rotation. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Callysponine (1) did not inhibit the growth of HepG2 (hepatoma carcinoma cell), A549 (lung carcinoma cell), and HeLa (cervical cancer cell) cell lines. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
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