47 results on '"Rezzani, C."'
Search Results
2. ECRHS Screening Questionnaire Scoring: A Methodological Suggestion for Asthma Assessment.
- Author
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Biino, G., Rezzani, C., Grassi, M., and Marinoni, A.
- Abstract
Investigated the unidimensionality of the European Community Respiratory Health Survey (ECRHS) screening questionnaire and determined and validated a scoring of asthma-like symptoms seriousness. Data from 6,946 adults at 3 Italian screening centers found a single dimension underlying the screening questionnaire. A scoring of asthma-like symptoms was determined. (SLD)
- Published
- 2001
3. Sleep continuity scale in Alzheimer’s disease (SCADS): application in daily clinical practice in an Italian center for dementia
- Author
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Manni, R., Sinforiani, E., Terzaghi, M., Rezzani, C., and Zucchella, C.
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- 2015
- Full Text
- View/download PDF
4. A sleep continuity scale in Alzheimer’s disease: validation and relationship with cognitive and functional deterioration
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Manni, R., Sinforiani, E., Zucchella, C., Terzaghi, M., and Rezzani, C.
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- 2013
- Full Text
- View/download PDF
5. The DYMUS questionnaire for the assessment of dysphagia in multiple sclerosis
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Bergamaschi, R., Crivelli, P., Rezzani, C., Patti, F., Solaro, C., Rossi, P., Restivo, D., Maimone, D., Romani, A., Bastianello, S., Tavazzi, E., D'Amico, E., Montomoli, C., and Cosi, V.
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- 2008
- Full Text
- View/download PDF
6. Validation of the Dutch Eating Behaviour Questionnaire parent version (DEBQ-P) in the Italian population: a screening tool to detect differences in eating behaviour among obese, overweight and normal-weight preadolescents
- Author
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Caccialanza, R, Nicholls, D, Cena, H, Maccarini, L, Rezzani, C, Antonioli, L, Dieli, S, and Roggi, C
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- 2004
- Full Text
- View/download PDF
7. Reliability of a dietary questionnaire on food habits, eating behaviour and nutritional knowledge of adolescents
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Turconi, G, Celsa, M, Rezzani, C, Biino, G, Sartirana, M A, and Roggi, C
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- 2003
- Full Text
- View/download PDF
8. Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy
- Author
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Solaro, C., primary, Cuccaro, A., additional, Gamberini, G., additional, Patti, F., additional, D’Amico, E., additional, Bergamaschi, R., additional, Berra, E., additional, Giusti, A., additional, Rezzani, C., additional, Messmer Uccelli, M., additional, and Grasso, M. G., additional
- Published
- 2019
- Full Text
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9. Gilbertʼs syndrome and fluorouracil toxicity in colorectal cancer patients: which correlation?
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Mandalà, M., Cremonesi, M., Cazzaniga, M., Rezzani, C., Ghilardi, M., Mary, C., Ferretti, G., and Barni, S.
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- 2004
10. A New Self-Report Quality of Life Questionnaire for Children With Neuromuscular Disorders
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Orcesi, S., Ariaudo, G., Mercuri, E., Beghi, E., Rezzani, C., Balottin, U., Angelini, Corrado, Berardinelli, A., Bertini, E., Boffi, P., Dall'Oglio, A., D'Amico, A., Filippini, M., Gorni, K., Lanzarotti, C., Messina, S., Olivieri, I., Palmieri, Arianna, Palmucci, L., Pane, M., Pini, A., and Rossi, M.
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Male ,Parents ,medicine.medical_specialty ,Adolescent ,media_common.quotation_subject ,Context (language use) ,Presentation ,Quality of life (healthcare) ,Surveys and Questionnaires ,medicine ,Humans ,Child ,Self report ,media_common ,business.industry ,Neuromuscular Diseases ,Therapeutic trial ,Muscular Dystrophy, Duchenne ,Socioeconomic Factors ,Case-Control Studies ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Quality of Life ,Physical therapy ,Feasibility Studies ,Female ,Self Report ,Neurology (clinical) ,business - Abstract
Improvement of quality of life in neuromuscular disorders is a primary objective, both in management of affected children and in the context of therapeutic trials. Quality of life is a subjective concept and it is crucial to gather information directly from patients. We created the SOLE Questionnaire for NMDs, a new instrument designed to investigate quality of life in children with neuromuscular disorders, and tested it in a study population of 78 patients and in 81 healthy children aged 5 to 13 years. The SOLE Questionnaire, characterized by a visual and neutral approach, was well received, practical, rapid to administer, and able to discriminate between patients and controls. We also confirmed the presence of disagreement about children’s quality of life between children and their parents. We suggest that our new approach could help to improve understanding of quality of life in children with neuromuscular disorders.
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- 2013
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- View/download PDF
11. Patient-reported outcomes measure for children born preterm: validation of the SOLE VLBWI Questionnaire, a new quality of life self-assessment tool
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Olivieri, I., M Bova, S., Fazzi, E., Ricci, Daniela, Tinelli, F., Montomoli, C., Rezzani, C., Balottin, U., Orcesi, S., Ariaudo, G., Capone, L., Spairani, S., Stronati, M., Figar, T., Mastrangelo, Marica, Krachmalnicoff, A., Lista, G., Accorsi, P., Martelli, P., Rossi, A., Micheletti, S., Zaccagnino, M., Chirico, G., Mallardi, M., Quintiliani, Michela, Romeo, Domenico Marco, Gallini, Francesca, Battini, Roberta, and Comparini, A.
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Self-assessment ,Male ,Self-Assessment ,Psychometrics ,Neurology (clinical) ,Pediatrics, Perinatology and Child Health ,Developmental Neuroscience ,Pediatrics ,Developmental psychology ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Cronbach's alpha ,030225 pediatrics ,Surveys and Questionnaires ,Humans ,Infant, Very Low Birth Weight ,Medical history ,Patient Reported Outcome Measures ,Child ,Measure (data warehouse) ,Alpha Value ,Very Low Birth Weight ,Infant ,Reproducibility of Results ,Perinatology and Child Health ,Focus group ,Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA ,Quality of Life ,Female ,Psychology ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
Aim This study was conducted to develop and validate a new self-report questionnaire for measuring quality of life (QoL), at school age, in children with a very low birthweight (VLBW). Method Through a focus group approach, children were involved directly in defining the questionnaire items, which were presented as illustrations rather than written questions. This preliminary validation of the questionnaire was conducted in 152 participants with VLBW (aged 7–11y) randomly selected from the five participating Italian centres. The questionnaire was completed by children and parents separately; data on children's demographic and medical history, and intellectual, adaptive, and behavioural functioning were collected using standardized scales. All the children also completed the Paediatric Quality of Life Inventory (PedsQL), another Italian-language measure of QoL in children. Results Our questionnaire was readily accepted and understood, and quick to complete. The Cronbach's alpha value showed it to be a reliable instrument. The child-compiled version correlated well with the PedsQL, whereas no correlations emerged with the other scales used, IQ, or degree of impairment. Conversely, these variables correlated significantly with the parent-compiled version. Children's and parents’ answers were divergent on practically all the items. Interpretation The results confirm the validity of the new instrument and highlight a poor overlap between parents’ and children's perspectives.
- Published
- 2016
12. Single-Agent Epirubicin as Primary Chemotherapy in T2–T3, N0–N2, M0 Breast Carcinoma: 6-Year Follow-Up
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Barni, S, Piazza, E, Frontini, L, Visini, M, Ardizzoia, A, Grassi, Mm, Nosenzo, Ma, Mandala', M, Biasioli, R, Freddi, E, Lucani, L, Recalcati, A, Pravettoni, A, Sala, R, Rezzani, C, Villa, S, Trabucchi, E, and Neo-Adjuvant Breast Italian Group
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Adult ,Oncology ,Cancer Research ,medicine.medical_specialty ,medicine.medical_treatment ,Mammary gland ,Breast Neoplasms ,Mastectomy, Segmental ,Disease-Free Survival ,Mastectomy, Modified Radical ,Breast cancer ,Internal medicine ,Carcinoma ,Humans ,Medicine ,skin and connective tissue diseases ,Aged ,Epirubicin ,Chemotherapy ,Antibiotics, Antineoplastic ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Clinical trial ,Treatment Outcome ,medicine.anatomical_structure ,Italy ,Lymphatic Metastasis ,Female ,business ,Breast carcinoma ,Mastectomy ,Follow-Up Studies ,medicine.drug - Abstract
Objective: Single-agent epirubicin was tested as primary chemotherapy treatment in patients with early breast cancer >3 cm. Methods: 100 women with locally advanced breast cancer >3 cm were treated with three cycles of single-agent epirubicin at a dose of 120 mg/m2. All patients showing tumor shrinkage to less than 3 cm were considered candidates for conservative surgery (quadrantectomy); in the remaining patients modified radical mastectomy was carried out. Postsurgical treatment consisted of CMF chemotherapy except for postmenopausal node-positive, estrogen-positive patients who were assigned to hormonal treatment with tamoxifen and postmenopausal node-negative, estrogen-positive ones who did not receive any treatment. Results: Quadrantectomy was carried out in 71 patients. At the median follow-up time of 69 months, the relapse rate was 29.6% among patients who underwent quadrantectomy (21 out of 71) and 58.6% among patients who underwent modified radical mastectomy (17 out of 29). Conclusions: Single-agent chemotherapy with anthracyclines could appear to be an effective treatment in inducing a tumor downstaging in patients with early breast cancer >3 cm. This treatment can be administered outside clinical trials in patients who desire to preserve their body integrity. Further prospective, randomized trials are needed in order to validate and better define the role of epirubicin in the neoadjuvant strategy of breast cancer patients.
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- 2004
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13. Validation of the DYMUS questionnaire for the assessment of dysphagia in multiple sclerosis
- Author
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BERGAMASCHI R, REZZANI C, MINGUZZI S, AMATO MP, PATTI F, MARROSU MG, S, GRASSO MG, GHEZZI A, ROTTOLI M, GASPERINI C, RESTIVO D, MAIMONE D, ROSSI P, STROMILLO ML, MONTOMOLI C, SOLARO C, GROUP D., BONAVITA, Simona, Bergamaschi, R, Rezzani, C, Minguzzi, S, Amato, Mp, Patti, F, Marrosu, Mg, Bonavita, Simona, S, Grasso, Mg, Ghezzi, A, Rottoli, M, Gasperini, C, Restivo, D, Maimone, D, Rossi, P, Stromillo, Ml, Montomoli, C, Solaro, C, and Group, D.
- Published
- 2009
14. Quality of life in very low birth weight children': development of the SOLE questionnaire
- Author
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Rezzani, C., Orcesi, S., Olivieri, I., Bova, S., Balottin, U., Montomoli, C., Rossi, Andrea, the Sole VLBWI Questionnaire Study Group, SISMEC, C., Rezzani, S., Orcesi, I., Olivieri, S., Bova, U., Balottin, C., Montomoli, Rossi, Andrea, and the Sole VLBWI Questionnaire Study, Group
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Quality of life ,Questionnaires ,very low birth weight - Published
- 2011
15. Malattia di Parkinson: valutazione di scale di funzionalità come indicatori d’efficacia del trattamento riabilitativo
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Pizzaballa, Gloria, Rezzani, C., Buscone, S., Boso, Marianna, Broglia, Davide, and Caverzasi, Edgardo
- Abstract
In letteratura sono presenti numerosi lavori volti a ricercare l’efficacia del trattamento riabilitativo nella Malattia di Parkinson. Tuttavia, questi studi presentano spesso limitazioni di tipo metodologico in quanto utilizzano, nella valutazione del miglioramento delle performance motorie e dell’indipendenza nelle attività della vita quotidiana, scale di valutazione che non sono però mai state validate a tale fine. Il presente studio ha permesso di identificare l’UPDRS - parte III e la FIM come scale che per le loro caratteristiche risultano particolarmente adatte ed affidabili, non solo per fotografare il grado di danno funzionale presente nel soggetto, ma anche, e soprattutto, per quantificare e caratterizzare l’effetto del trattamento riabilitativo., Bollettino della Società Medico Chirurgica di Pavia, Vol 122, N° 4 (2009)
- Published
- 2010
- Full Text
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16. Validation study of the italian questionnaire for the assessment of dysphagia in multiple sclerosis (DYMUS)
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Bergamaschi, R, Crivelli, P, Patti, Francesco, Rezzani, C, Solaro, C, Rossi, P, Restivo, Da, Romani, A, Bastianello, S, Montomoli, C, Alfonsi, E, and Cosi, V.
- Published
- 2007
17. Allergic rhinitis and asthma comorbidity in a survey of young adults in Italy
- Author
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Bugiani, M., Carosso, A., Migliore, E., Piccioni, P., Corsico, A., Olivieri, M., Ferrari, M., Pirina, P., Marinoni, R. de Marco on behalf of ISAYA: Principal researchers: A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Casali, L., Cerveri, I., Zoia, M. C., Colato, S., Moscato, G., Perfetti, L., Alesina, R., Basso, O., Berrayah, L., Brusotti, R., Fanfulla, F., Moi, P., Frati, C., Karytinos, P., Arossa, W., Caria, E., Castiglioni, G., Romano, Canzio, Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, P., Bono, Roberto, Gigli, G., Giraudo, A., Brussino, M. C., Bucca, Caterina, Rolla, Giovanni, Aime, M., Cerutti, A., Chiampo, F., Gallo, W., Sulotto, F., de Marco, R., Verlato, G., Accordini, S., Zanolin, M. E., Locatelli, F., Cazzoletti, L., Pattaro, C., Sartori, S., Poli, A., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Biasin, C., Campello, C., Rossi, F., Cannistra`, A., Cenci, B., Destefani, E., Girotto, M., Lampronti, G., Martini, C., Tardivo, S., Villani, A., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., P. Natale, M. Grosa, Tacconi, A., Frontero, P., and Salomoni, A.
- Published
- 2005
18. The role of climate on the geographic variability of asthma, allergic rhinitis and respiratory symptoms: results from the Italian study of asthma in young adults
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Zanolin, M. E., Pattaro, C., Corsico, A., Bugiani, M., Carrozzi, L., Casali, L., Dallari, R., Ferrari, M., Marinoni, A., Migliore, E., Olivieri, M., Pirina, P., Verlato, G., Villani, S., de Marco, R., Buriani, O., Cavallini, R., Saletti, C., Cellini, M., Faustini, M., de Togni, A., Carolei, A., Montomoli, C., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Cerveri, I., Zoia, M. C., Colato, S., Moscato, G., Perfetti, L., Viegi, G., Pistelli, F., di Pede, F., Paggiaro, P. L., Santolicandro, A., Giovannetti, P., Ginesu, F., Ostera, S., Pinna, G. P., Farre, A., Imparato, S., Turrini, E., Foglia, M., Giammanco, G., Pignato, S., Rotondo, A., Cuspilici, A., Piccioni, P., Carosso, A., Arossa, W., Caria, E., Castiglioni, G., Romano, C., Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, P., Bono, R., Gigli, G., Giraudo, A., Brussino, M. C., Bucca, C., Rolla, G., Struzzo, P., Orefice, U., Schneider, M., Chittaro, F., Peresson, D., Accordini, S., Locatelli, F., Cazzoletti, L., Sartori, S., Poli, A., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Biasin, C., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., Natale, P., Grosa, M., Tacconi, A., Frontero, P., and Salomoni, A.
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Adult ,medicine.medical_specialty ,Allergy ,Rhinitis, Allergic, Perennial ,Climate ,Immunology ,Geographic pattern ,Allergic ,Epidemiology ,medicine ,Prevalence ,Immunology and Allergy ,Humans ,Asthma epidemiology ,Asthma prevalence allergy ,Latitude ,Asthma ,Chronic Disease ,Cough ,Geography ,Regression Analysis ,Rhinitis, Allergic, Seasonal ,Rhinitis ,Seasonal ,business.industry ,Phlegm ,Respiratory disease ,Odds ratio ,medicine.disease ,Perennial ,respiratory tract diseases ,Chronic cough ,Etiology ,medicine.symptom ,business ,Demography - Abstract
Background: Variations in the prevalence of respiratory symptoms according to geo-climatic factors could provide important clues to the knowledge of the aetiology of asthma. Methods: Geo-climatic variations in the prevalence of current asthma, allergic rhinitis and chronic cough, and phlegm were assessed on a random sample of 18 873 subjects (response rate = 72.7%) from different climatic regions of Italy. An ecological analysis, supported by robust statistical methods, was employed to investigate potential trends. Results: The prevalence of all symptoms was significantly heterogeneous throughout the peninsula. Only asthma-like symptoms showed a north–south trend: the prevalence increased at a decreasing latitude [odds ratio (OR) varies from 0.92 to 0.96, P
- Published
- 2004
19. The role of climate on the geographic variability of asthma, allergicrhinitis and respiratory symptoms: results from the Italian study of asthma in young adults
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Zanolin, M. E., Pattaro, C., Corsico, . A., Bugiani, M., Carrozzi, L., Casali, . L., Dallari, R., Ferrari, M., Marinoni, . A., Migliore, E., Olivieri, M., P. P. i. r. i. n. a., . G. Verlato, Villani, . S., Demarco, R., Buriani, . O., Cavallini, R., Saletti, C., Cellini, M., Faustini, M., de Togni, A., Marinoni, A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, . M., Grassi, M., Rezzani, C., Casali, L., Cerveri, I., Zoia, M. C., Corsico, A., Colato, S., Moscato, G., Perfetti, . L., Viegi, G., Pistelli, F., Di Pede, F., Paggiaro, P. L., Santolicandro, A., Giovannetti, P., Ginesu, F., Pirina, P., Ostera, S., Pinna, G. P., Farre, A., Imparato, S., Turrini, E., Foglia, . M., Giammanco, G., Pignato, S., Rotondo, . A., Cuspilici, A., Piccioni, P., Carosso, . A., Arossa, W., Caria, E., Castiglioni, G., Romano, Canzio, Fabbro, D., Ciccone, G., Magnani, . C., Dalmasso, P., Bono, Roberto, Gigli, G., Giraudo, A., Brussino, Luisa, Bucca, Caterina, Rolla, Giovanni, Struzzo, P., Orefice, . U., Schneider, M., Chittaro, F., Peresson, D., de Marco, R., Verlato, G., Accordini, S., Locatelli, F., Cazzoletti, L., Sartori, S., Poli, . A., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Biasin, C., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., P. Natale, M. Grosa, Tacconi, A., Frontero, P., and Salomoni, A.
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climate ,asthma ,allergic rhinitis ,respiratory symptoms - Published
- 2004
20. Sleep continuity scale in Alzheimer’s disease (SCADS): application in daily clinical practice in an Italian center for dementia
- Author
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Manni, R., primary, Sinforiani, E., additional, Terzaghi, M., additional, Rezzani, C., additional, and Zucchella, C., additional
- Published
- 2014
- Full Text
- View/download PDF
21. Is the prevalence of adult asthma and allergic rhinitis still increasing? Results of an Italian study
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Verlato, G, Corsico, A, Villani, S, Cerveri, I, Migliore, E, Accordini, S, Carolei, A, Piccioni, P, Bugiani, M, Lo Cascio, V, Marinoni, A, Poli, A, Ecrhs, de Marco R., Marinoni, ISAYA group Principal researchers: A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Casali, L., Cerveri, I., Zoia, M. C., Corsico, A., Colato, S., Moscato, G., Perfetti, L., Alesina, R., Basso, O., Berrayah, L., Brusotti, R., Fanfulla, F., Moi, P., Frati, C., Karytinos, P., Bugiani, M., Piccioni, P., Carosso, A., Arossa, W., Caria, E., Castiglioni, G., Migliore, E., Romano, C., Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, Paola, Bono, Roberto, Gigli, G., Giraudo, A., Brussino, Luisa, Bucca, Caterina, Rolla, Giovanni, Aime, M., Cerutti, A., Chiampo, F., Gallo, W., Sulotto, F., de Marco, R., Verlato, G., Accordini, S., Zanolin, M. E., Locatelli, F., Cazzoletti, L., Pattaro, C., Sartori, S., Poli, A., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Olivieri, M., Ferrari, M., Biasin, C., Campello, C., Rossi, F., Cannistrà, A., Cenci, B., Destefani, E., Girotto, M., Lampronti, G., Martini, C., Tardivo, S., Villani, A., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., Natale, P., Grosa, M., Tacconi, A., Frontero, P., and Salomoni, A.
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Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Allergy ,Rhinitis, Allergic, Perennial ,temporal trend ,Immunology ,Logistic regression ,asthma, allergic rhinitis, temporal trend, epidemiology ,Epidemiology ,Prevalence ,Immunology and Allergy ,Medicine ,Humans ,Non-response bias ,Young adult ,Asthma ,Response rate (survey) ,allergic rhinitis ,business.industry ,Rhinitis, Allergic, Seasonal ,Odds ratio ,asthma ,medicine.disease ,Italy ,Female ,epidemiology ,business - Abstract
The prevalence of asthma and allergic rhinitis has increased worldwide during the 1970s and 1980s.This study was aimed at evaluating whether the increasing trend in prevalence persisted during the 1990s in the young adult Italian population.In 1998 to 2000 a screening questionnaire was sent by mail to a general population sample aged 20 to 44 years; nonresponders were contacted again first by mail and then by phone, achieving a final response rate of 78.1% (6876 of 8800). Prevalence estimates, adjusted to correct for nonresponse bias, were compared with those recorded in Italy in 1991 to 1993 during the European Community Respiratory Health Survey, when response rate had been slightly higher (87.6%). Temporal variations in symptom prevalence were analyzed by a logistic regression model, controlling for sex, age, site of residence (urban vs suburban areas), season of response, response rate, and type of contact (mail vs phone).The prevalence of asthma attacks did not vary significantly from 1991 to 1993 (3.6%) to 1998 to 2000 (3.2%) (P =.188). The prevalence of asthma-like symptoms (wheezing, chest tightness, shortness of breath) tended to decrease in the age classes of 32.5 to 45 years, while increasing in the youngest age class (20 to 26 years). A clear-cut increase from 15.4% to 18.3% was observed for the prevalence of allergic rhinitis (P.001), whereas the proportion of people under antiasthmatic treatment increased in suburban areas but not in urban areas (interaction time-site of residence, P.001).Asthma prevalence has not increased during the last decade in Italy. The persistence of an increasing trend in allergic rhinitis prevalence deserves attention.
- Published
- 2003
22. Some aspects of principal components analysis as measurement error model
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Grassi, M., Rezzani, C., Biino, G., Grassi, M., Rezzani, C., and Biino, G.
- Abstract
In this paper , Principal Component Analysis (PCA) is formulated within a likelihood framework, based on a specific form of Gaussian model. We suggest how the principal axes of observed data vectors may be determined through maximum-likelihood estimation of parameters in a latent variable model closely related to a Factor Analysis and Error-in-Variables Models. We consider the properties of the associated likelihood function and discuss the advantages conveyed by the definition of a probability density function for PCA. The numeric/graphical quantities of the usual output now represent the maximum likelihood estimates of the parameters of a probabilistic model, rather than approximations of an algebraic-geometric algorithm. The use of PCA as method of analysis communicated by the interpretation of the principal components: we determine the subdivision a posteriori predictors of redundant variables. We investigate the proposed model in a case-control study of cardiovascular disease.
- Published
- 2013
23. Incidence and remission of asthma: a retrospective study on the natural history of asthma in Italy
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De Marco, R., Locatelli, F., Cerveri, I., Bugiani, M., Marinoni, A., Giammanco, G., Accordini, S., Verlato, G., Zanolin, E., Buriani, O., Carrozzi, L., Dallari, R., Ginesu, F., Poli, A., Struzzo, P., Cavallini, R., Saletti, C., Cellini, M., Faustini, M., De Togni, A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Casali, L., Zoia, M. C., Corsico, A., Colato, S., Moscato, G., Perfetti, L., Viegi, G., Pistelli, F., Di Pede, F., Paggiaro, P. L., Santolicandro, A., Giovannetti, P., Pirina, P., Ostera, S., Pinna, G. P., Farre, A., Imparato, S., Turrini, E., Foglia, M., Pignato, S., Rotondo, A., Cuspilici, A., Piccioni, P., Carosso, A., Arossa, W., Caria, E., Castiglioni, G., Migliore, E., Romano, C., Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, P., Bono, R., Gigli, G., Giraudo, A., Brussino, M. C., Bucca, C., Rolla, G., Orefice, U., Schneider, M., Chittaro, F., Peresson, D., Zanolin, M. E., Cazzoletti, L., Battisti, L., Pattaro, C., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Olivieri, M., Ferrari, M., Biasin, C., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., Natale, P., Grosa, M., Tacconi, A., Frontero, P., and Salomoni, A.
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Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,National Health Programs ,Remission ,Cross-sectional study ,Immunology ,Population ,Remission, Spontaneous ,Rate ratio ,Asthma remission ,Asthma incidence ,Persistence of asthma ,Asthma ,Child ,Child, Preschool ,Cross-Sectional Studies ,Female ,Humans ,Incidence ,Infant ,Infant, Newborn ,Italy ,Retrospective Studies ,medicine ,Immunology and Allergy ,Young adult ,Preschool ,education ,education.field_of_study ,business.industry ,Spontaneous ,Incidence (epidemiology) ,Retrospective cohort study ,Newborn ,medicine.disease ,Natural history ,business - Abstract
The knowledge of the natural history of asthma from birth to adulthood could provide important clues for its cause and for the understanding of epidemiologic findings.This study is aimed at assessing the incidence and remission of asthma from birth to the age of 44 years by using data from 18,873 subjects involved in a large, nationally representative, cross-sectional study carried out in Italy from 1998 through 2000.The onset of asthma was defined as the age at the first attack, and remission was considered present when a subject was neither under treatment nor had experienced an asthma attack in the last 24 months. Person-years and survival techniques were used for the analysis.The average annual incidence rate for the 1953 to 2000 period was 2.56/1000 persons per year. Incidence peaked in boys less than 10 years of age (4.38/1000 persons per year) and in women 30 years of age or older (3.1/1000 persons per year) and showed a generational increase (incident rate ratio = 2.63 and 95% CI = 2.20-3.12 for 1974-1979 vs 1953-1958 birth cohort). The overall remission rate was 45.8% (41.6% in women and 49.5% in men, P.001). Asthmatic patients in remission had an earlier age at onset (7.8 vs 15.9 years, P.001) and a shorter duration of the disease (5.6 vs 16.1 years, P.001) than patients with current asthma. The probability of remission was strongly (P.001) and inversely related to the age at onset (62.8% and 15.0% in the10- andor =20-years age-at-onset groups, respectively).With respect to its natural history, asthma presents 2 different forms: early-onset asthma, which occurs early in childhood, affects mainly boys, and has a good prognosis, and late-onset asthma, which generally occurs during or after puberty, mainly affects women, and has a poor prognosis. The minority of patients with early-onset asthma who do not remit represents more than 35% of patients with current asthma in the general young adult population.
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- 2002
24. Incidence and remission of asthma: A retrospective study on the natural history of asthma in Italy
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de Marco, R, Locatelli, F, Cerveri, I, Bugiani, M, Marinoni, A, Giammanco, G, Buriani, for the Italian Study on Asthma in Young Adults study group Principal researchers: O., Cavallini, R., Saletti, C., Cellini, M., Faustini, M., de Togni, A., Marinoni, A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Casali, L., Cerveri, I., Zoia, M. C., Corsico, A., Colato, S., Moscato, G., Perfetti, L., Carrozzi, L., Viegi, G., Pistelli, F., Di Pede, F., Paggiaro, P. L., Santolicandro, A., Giovannetti, P., Ginesu, F., Pirina, P., Ostera, S., Pinna, G. P., Farre, A., Imparato, S., Dallari, R., Turrini, E., Foglia, M., Giammanco, G., Pignato, S., Rotondo, A., Cuspilici, A., Bugiani, M., Piccioni, P., Carosso, A., Arossa, W., Caria, E., Castiglioni, G., Migliore, E., Romano, Canzio, Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, Paola, Bono, Roberto, Gigli, G., Giraudo, A., Brussino, Luisa, Bucca, Caterina, Rolla, Giovanni, Struzzo, P., Orefice, U., Schneider, M., Chittaro, F., Peresson, D., de Marco, R., Verlato, G., Accordini, S., Zanolin, M. E., Locatelli, F., Cazzoletti, L., Battisti, L., Pattaro, C., Poli, A., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Olivieri, M., Ferrari, M., Biasin, C., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., P. Natale, M. Grosa, Tacconi, A., Frontero, P., and Salomoni, A.
- Published
- 2002
25. Prevalence of patient-reported dysphagia in multiple sclerosis patients: An Italian multicenter study (using the DYMUS questionnaire)
- Author
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Solaro, C., primary, Rezzani, C., additional, Trabucco, Erika, additional, Amato, M.P., additional, Zipoli, V., additional, Portaccio, E., additional, Giannini, M., additional, Patti, F., additional, D'Amico, E., additional, Frau, J., additional, Lorefice, L., additional, Bonavita, S., additional, Corte, M. Della, additional, Grasso, M.G., additional, Finamore, L., additional, Ghezzi, A., additional, Annovazzi, P., additional, Rottoli, M., additional, Gasperini, C., additional, Restivo, D., additional, Maimone, D., additional, Rossi, P., additional, Stromillo, M.L., additional, and Bergamaschi, R., additional
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- 2013
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26. A sleep continuity scale in Alzheimer’s disease: validation and relationship with cognitive and functional deterioration
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Manni, R., primary, Sinforiani, E., additional, Zucchella, C., additional, Terzaghi, M., additional, and Rezzani, C., additional
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- 2012
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27. Risk factors in medication-overuse headache: A 1-year follow-up study (care II protocol)
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Sances, G, primary, Ghiotto, N, additional, Galli, F, additional, Guaschino, E, additional, Rezzani, C, additional, Guidetti, V, additional, and Nappi, G, additional
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- 2009
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28. WinCHIP: Computerised Homeopathic Investigation Program: a data collection tool to help the doctor in daily practice to prove and improve homeopathy
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Rezzani, C M, primary
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- 2000
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29. Asthmatics and ex-smokers respond early, heavy smokers respond late to mailed surveys in Italy
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Verlato, Giuseppe, Melotti, Roberto, Olivieri, Mario, Corsico, Angelo, Bugiani, Massimiliano, Accordini, Simone, Villani, Simona, Migliore, Enrica, Marinoni, Alessandra, Pirina, Pietro, Carrozzi, Laura, Bortolami, Oscar, Rava, Marta, de Marco, Roberto, Accordini, S., Verlato, G., Zanolin, E., Bugiani, M., Buriani, O., Carrozzi, L., Dallari, R., Giammanco, G., Ginesu, F., Marinoni, A., Poli, A., Struzzo, Pierluigi, Cavallini, R., Saletti, C., Cellini, M., Faustini, M., de Togni, A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Casali, L., Cerveri, I., Zoia, M. C., Corsico, A., Colato, S., Moscato, G., Perfetti, L., Viegi, G., Pistelli, F., Di Pede, F., Paggiaro, P. L., Santolicandro, A., Giovannetti, P., Pirina, P., Ostera, S., Pinna, G. P., Farre, A., Imparato, S., Turrini, E., Foglia, M., Pignato, S., Rotondo, A., Cuspilici, A., Piccioni, P., Carosso, A., Arossa, W., Caria, E., Castiglioni, G., Migliore, E., Romano, C., Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, P., Bono, R., Gigli, G., Giraudo, A., Brussino, M. C., Bucca, C., Rolla, G., Struzzo, P., Orefice, U., Schneider, M., Chittaro, F., Peresson, D., de Marco, R., Zanolin, M. E., Locatelli, F., Cazzoletti, L., Pattaro, C., Sartori, S., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Ferrari, M., Biasin, C., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., Natale, P., Grosa, M., Tacconi, A., Frontero, P., Salomoni, A., Verlato, Giuseppe, Melotti, Roberto, Olivieri, Mario, Corsico, Angelo, Bugiani, Massimiliano, Accordini, Simone, Villani, Simona, Migliore, Enrica, Marinoni, Alessandra, Pirina, Pietro, Carrozzi, Laura, Bortolami, Oscar, Rava, Marta, de Marco, Roberto, Accordini, S., Verlato, G., Zanolin, E., Bugiani, M., Buriani, O., Carrozzi, L., Dallari, R., Giammanco, G., Ginesu, F., Marinoni, A., Poli, A., Struzzo, Pierluigi, Cavallini, R., Saletti, C., Cellini, M., Faustini, M., de Togni, A., Carolei, A., Montomoli, C., Villani, S., Comelli, M., Ponzio, M., Grassi, M., Rezzani, C., Casali, L., Cerveri, I., Zoia, M. C., Corsico, A., Colato, S., Moscato, G., Perfetti, L., Viegi, G., Pistelli, F., Di Pede, F., Paggiaro, P. L., Santolicandro, A., Giovannetti, P., Pirina, P., Ostera, S., Pinna, G. P., Farre, A., Imparato, S., Turrini, E., Foglia, M., Pignato, S., Rotondo, A., Cuspilici, A., Piccioni, P., Carosso, A., Arossa, W., Caria, E., Castiglioni, G., Migliore, E., Romano, C., Fabbro, D., Ciccone, G., Magnani, C., Dalmasso, P., Bono, R., Gigli, G., Giraudo, A., Brussino, M. C., Bucca, C., Rolla, G., Struzzo, P., Orefice, U., Schneider, M., Chittaro, F., Peresson, D., de Marco, R., Zanolin, M. E., Locatelli, F., Cazzoletti, L., Pattaro, C., Sartori, S., Dorigo, N., Cantarelli, S., Ciresola, D., Lo Cascio, V., Ferrari, M., Biasin, C., Lauriola, P., Danielli, G., Sesti, D., Ghigli, E., Natale, P., Grosa, M., Tacconi, A., Frontero, P., and Salomoni, A.
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Male ,Questionnaires ,Allergy ,asthmatics ,ex-smokers ,survey ,Allergic rhinitis ,Mail survey ,Epidemiology ,Prevalence ,Smoking habit ,Medicine ,Respiratory symptoms ,Young adult ,Response bias ,Medicine (all) ,Respiratory disease ,Phlegm ,Smoking ,Health Survey ,Middle Aged ,Chronic cough ,Italy ,Bias (Epidemiology) ,Female ,medicine.symptom ,Human ,Adult ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Logistic Model ,Response bia ,Young Adult ,Allergic rhiniti ,Humans ,Smoking habits ,Asthma ,Questionnaire ,business.industry ,medicine.disease ,Health Surveys ,Surgery ,respiratory tract diseases ,Logistic Models ,Cough ,mail survey, response bias, respiratory symptoms, asthma, allergic rhinitis, smoking habits ,Respiratory symptom ,Patient Compliance ,business ,Demography - Abstract
Summary Rationale and objectives Response to mailed epidemiological surveys has decreased in recent decades. Since subjects with respiratory symptoms are usually early responders to surveys performed in Southern Europe, this trend could bias prevalence estimates. The present study aimed at evaluating the impact of non-response bias on prevalence estimates of respiratory symptoms and smoking habits. Methods In 9 centres, participating in the Italian Study on Asthma in Young Adults (ISAYA), random samples of people aged 20–45 years were administered a mailed questionnaire between 1998 and 2000. Non-responders were contacted again first by mail and then by phone. Cumulative response percentage was 30.5%, 52.4% and 72.7% (18,873/25,969), respectively, after the 1st, 2nd and 3rd contact. Results The prevalence of self-reported current asthma, asthma-like symptoms, and chronic cough/phlegm was more than halved from the first contact (5.6%, 17.8%, 14.6% respectively) to the third contact (2.7%, 6.4%, 6.9%). This pattern was less pronounced when considering allergic rhinitis and past asthma, whose prevalence decreased, respectively, from 21.5% to 15.6% and from 3.5% to 2.6%. At the same time the proportion of current smokers increased from 29.2% to 38%, while the proportion of ex-smokers decreased from 16.5% to 10.1%. In a multinomial logistic model current asthma, asthma-like symptoms, chronic cough/phlegm and smoking habits, and to a lower extent past asthma and allergic rhinitis, were significant predictors of late response. Conclusions In Italy when response percentage is low, the prevalence of current asthma, chronic cough/phlegm and ex-smokers is overestimated, while the proportion of current smokers is underestimated.
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30. ECRHS screening questionnaire scoring: a methodological suggestion for asthma assessment. European Community Health Survey
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Biino, G., Rezzani, C., Mario Grassi, and Marinoni, A.
31. Validation of the DYMUS questionnaire for the assessment of dysphagia in multiple sclerosis
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Bergamaschi, R., Rezzani, C., Minguzzi, S., Amato, M. P., Patti, F., Marrosu, M. G., Bonavita, S., Grasso, M. G., Ghezzi, A., Rottoli, M., Gasperini, C., Restivo, D., Maimone, D., Rossi, P., Stromillo, M. L., Cristina Montomoli, Solaro, C., Romani, A., Bargiggia, V., Crivelli, P., Tavazzi, E., Zipoli, V., Giannini, M., Portaccio, E., Hakiki, B., D Amico, E., Cocco, E., Frau, J., Lorefice, L., Della Corte, M., Finamore, L., Annovazzi, P., Galgani, S., Judica, E., and Stefano, N.
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Adult ,Male ,Multiple Sclerosis ,Adolescent ,Reproducibility of Results ,Middle Aged ,Severity of Illness Index ,Disability Evaluation ,Young Adult ,Surveys and Questionnaires ,Humans ,Female ,Child ,Deglutition Disorders ,Factor Analysis, Statistical ,Aged - Abstract
Swallowing problems can complicate the course of multiple sclerosis (MS). However, no validated questionnaire for the assessment of dysphagia in MS is currently available. We previously developed a 10-item DYsphagia in Multiple Sclerosis questionnaire (DYMUS). In the present study, this questionnaire was submitted to a validation process. Thirteen Italian MS centres took part in this research in which DYMUS was administered to 1734 consecutive MS patients during routine checkups outside relapse. The questionnaire showed very good internal consistency (Cronbach's alpha = 0.914). It was then subdivided into two subscales, both of which also showed very good internal consistency: Cronbach's alpha was 0.885 for the 'dysphagia for solids' subscale and 0.864 for the 'dysphagia for liquids' subscale. The DYMUS questionnaire was found to be an easy and reliable tool for detecting dysphagia and also for the preliminary selection of patients requiring more specific instrumental analyses, and those suitable for aspiration prevention programmes.
32. Data collection in homeopathic practice: A suggestion for an international standard
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Steinsbekk, A., Biolchini, J., Heger, M., Rezzani, C., Tsamis, N., Robbert van Haselen, Witt, C., and Wittorff, M.
33. Evaluation of the efficacy of the Italian guidelines on COPD: a cluster randomized trial
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Tinelli, C., Rezzani, C., GINEVRA BIINO, Marinoni, A., Rossi, A., Volpini, E., Pistoria, A., Termini, R., and Grassi, M.
- Subjects
Male ,Guidelines ,family practice ,Middle Aged ,chronic obstructive pulmonary disease ,Pulmonary Disease, Chronic Obstructive ,Treatment Outcome ,Italy ,Practice Guidelines as Topic ,Quality of Life ,Humans ,Female ,Prospective Studies ,Aged ,Follow-Up Studies - Abstract
Question of the study. Chronic Obstructive Pulmonary Disease (COPD) is a profoundly disabling disease managed predominantly by General Practitioners (GPs). We planned this prospective trial to evaluate the applicability of Italian GP-directed guidelines in routine practice and whether adherence to them improves treatment efficacy, with respect to decreased exacerbations, hospital admissions, drug use, and out-patient appointments and improved quality of life (QoL). Materials and methods. In a cluster randomised trial, 22 GPs were randomly put into two groups: one group was asked to follow the guidelines (YES-GL), the other to continue normal clinical practice (NO-GL). These GPs enrolled 123 patients with COPD and followed them for one year. Results. Patients managed by the YES-GL GPs had more outpatient appointments and specialist consultations and a higher probability of being classified as having severe COPD. The QoL was fairly low in both groups, and all other clinical outcomes taken into consideration, were not affected by application of the guidelines. Answer to the question. In conclusion, the guidelines did not substantially alter the clinical evolution of COPD patients, even though some facets of management improved
34. 40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
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Veitenhansl, M., Stegner, K., Hierl, F-X, Dieterle, C., Feldmeier, H., Gutt, B., Landgraf, R., Garrow, A. P., Vileikyte, L., Findlow, A., Waterman, C., Boulton, A. J. M., Shankhdhar, K., Shankhdhar, L., Shankhdhar, U., Petrova, N. L., Foster, A. V. M., Edmonds, M. E., Ferraresi, R., Caravaggi, C., Giglio, R., Cavaiani, P., Pogliaghi, I., Sommariva, E., Katz, I. A., Harlan, A., Miranda-Palma, B., Prieto-Sanchez, L., Armstrong, D. G., Bowker, J. H., Mizel, M. S., Cernea, S., Wohlgelernter, J., Kidron, M., Modi, P., Raz, I., Arbit, E., Nosek, L., Kapitza, C., Beckett, P., Gelfand, R., Goldberg, M., Heise, T., Testa, M. A., Turner, R. R., Hayes, J. F., Scranton, R. E., Simonson, D. C., Yang, Y-W, Hsu, Y-J, Naujok, O., Francini, F., Jorns, A., Tiedge, M., Lenzen, S., Abdel-Wahab, Y. H. A., Marenah, L., Orr, D. F., Shaw, C., Flatt, P. R., Chokkalingam, K., Mansell, P. I., Clausen, P., Ekbom, P., Damm, P., Feldt-Rasmussen, U., Nielsen, B., Mathiesen, E. R., Feldt-Rasmussen, B., Dewan, S., Da Silva, N., Ternan, P. Mc, Leong, K. S., Wilding, J. P. H., Asatiani, N., Kurashvili, R., Dundua, M., Shelestova, E., Pagava, K., Ramazashvili, M., Hod, M., Smirnov, S., Petersen, J. L. A., Justesen, T. I., Ringholm Nielsen, L., Muller, C., Hojlund, K., Wensaas, A., Kase, E. T., Aas, V., Rustan, A. C., Thoresen, G. H., Levin, K., Beck-Nielsen, H., Gaster, M., Im, S-S, Kang, S-Y, Kim, S-Y, Ahn, Y-H, Lihn, A. S., Schmoll, D., Werner, T., Kienitz, A., Meyer, M., Barthel, A., Ailett, F., Sutherland, C., Walther, R., Grempler, R., Sasson, S., Reich, R., Tenenbaum, T., Alpert, E., Anfossi, G., Russo, I., Traversa, M., Massucco, P., Mattiello, L., Doronzo, G., Trovati, M., Lally, S., Tan, C. Y., Owens, D., Tomkin, G. H., Porchay, I., Pean, F., Bellili, N., Betoulle, D., Balkau, B., Tichet, J., Marre, M., Fumeron, F., Group D.E.S.I.R., Chatellier, G., Alhenc-Gelas, F., Diabhycar, Study Group, Nichols, G. A., Brown, J. B., Hayes, R. P., Bowman, L., Drexel, H., Saely, C. H., Marte, T., Benzer, W., Langer, P., Hoefle, G., Moll, W., Aczel, S., Karagiannis, E., Lubben, G., Urquhart, R., Edwards, G., Bruce, S., Howlett, H. S. C., Cugnardey, N., Turner, K. C., Park, J-S, Fiedorek, F. T., Avogaro, A., Gallo, A., Pinton, P., Rizzuto, R., Murphy, E., Ceolotto, G., Caterson, I., Guy-Grand, B., Hill, J., Barone, M., Aiello, A., Allochis, G., Borzi, V., Cannata, F., Caronna, S., D Avanzo, A., Elli, R., Formoso, G., Paroli, A., Scardapane, R., Sorichetti, P., Tatti, P., Viviani, G., Santeusanio, F., Italian Repaglinide Study Group, Manzella, D., Grella, R., Abbatecola, A. M., Paolisso, G., Sondergaard, L. G., Monster, T. B. M., Johnsen, S. P., Olsen, M. L., Mclaughlin, J. K., Sorensen, H. T., Lervang, H. H., Rungby, J., Lyssenko, V., Fredriksson, J., Almgren, P., Anevski, D., Orho-Melander, M., Sjogren, M., Tuomi, T., Groop, L., Jaziri, R., Aubert, R., Tuomilehto, J., Hu, G., Jousilahti, P., Peltonen, M., Lindstrom, J., Laina, A., Alevizaki, M., Philippou, G., Souvatzoglou, A., Anastasiou, E., Alba, S., Metcalf, B. S., Voss, L. D., Jeffery, A. N., Wilkin, T. J., Gluimer, C., Colagiuri, S., Vistisen, D., Borch-Johnsen, K., Haynes, A., Bower, C., Bulsara, M. K., Jones, T. W., Davis, E. A., Mortensen, H. B., Hougaard, P., Holl, R., Swift, P., Pociot, F., Knip, M., Hansen, L., Szadkowska, A., Pietrzak, I., Zmyslowska, A., Wyka, K., Bodalski, J., Holl, R. W., Swift, R., Hougaard, R., Gerstl, E-M, Engelsberger, I., Rabl, W., Rosenbauer, J., Grobe, H., Hofer, S. E., Krause, U., DPV-Wiss-Study Group, Dabelea, D., Morgan, T., Pettitt, D. J., Dolan, L., Mayer-Davis, E. J., Pihoker, C., Hillier, T. A., Imperatore, G., Ruggiero, A., Hamman, R. E., Stylianou, A., Tentolouris, N., Perrea, D., Tselepis, A. D., Lourida, E., Kitsou, E., Katsilambros, N., Vedovato, M., Dodesini, A. R., Lepore, G., Tiengo, A., Trevisan, R., Penno, G., Miccoli, R., Pucci, L., Lucchesi, D., Bandinelli, S., Fotino, C., Triscornia, S., Baldassari, E., Del Prato, S., Reboldi, P., Santeusanio, E., Fuller, J., Langham, R. G., Gow, R. M., Zhang, Y., Kelly, D. J., Christensen, P. K., Parving, H-H, Gilbert, R. E., Chibalin, A. V., Zhong, Z., Kotova, O., Davidescu, A., Ehren, I., Ekberg, K., Wahren, J., Wassef, L., Buckley, A. J., Rooney, K. B., Briody, J., Thompson, M., Ozanne, S. E., Thompson, C. H., Chamson-Reig, A., Summers, K., Arany, E. J. R., Hill, D. J., Solerte, S. B., Gazzaruso, C., Locatelli, E., Precerutti, S., Schifino, N., Ferrari, E., Fioravanti, M., Phenekos, C. V., Ginis, A., Fragaki, I., Chalkiadaki, M., Tzioras, C., Powell, L. A., Mcguire, G. M., Jewhurst, V., Trimble, E. R., Rasmussen, B. M., Vessby, B., Uusitupa, M., Berglund, L., Pedersen, E., Riccardi, G., Rivellese, A. A., Tapsell, L., Hermansen, K., Kanwu, Study Group, Da Silva Xavier, G., Rutter, J., Rutter, G. A., Briaud, I. M., Lingohr, M. K., Dickson, L. M., Mccuaig, J. R., Lawrence, J. C., Rhodes, C. J., Wikstrom, J. D., Katzman, S. M., Shirihai, O. S., Yang, J., Deng, S., Wang, X., Hessner, M. J., Wu, J., Wong, R. K., Sukumvanich, S., Markman, J. F., Naji, A., Wolf, B. A., Gao, Z., Rubi, B., Del Arco, A., Satrustegui, J., Maechler, P., Del Guerra, S., Lupi, R., Bugliani, M., Sbrana, S., Torri, S., Boggi, U., Vistoli, F., Mosca, F., Marchetti, P., Rennings, A. J. M., Smits, P., Stewart, M. W., Tack, C. J. J., Li, L., Nystrom, T., Gutniak, M., Ahren, B., Holst, J., Sjoholm, A., Gomes, M. B., Cailleaux, S., Tibirica, E., Albertini, J-P, Chen, H., Mather, R., Valensi, P. E., Chisalita, S. I., Arnqvist, H. J., Kraenkel, N., Adams, V., Linke, A., Gielen, S., Schuler, G., Humbrecht, R., Cipollone, F., Iezzi, A., Fazia, M., Pini, B., Cucurullo, C., Cesare, D., Schmidt, A. M., Mazurek, T., Zang, L. F., Mannion, J., Diehl, J., Martin, J., Martella, A., Zalewski, A., Shi, Y., Otter, W., Winter, M., Doering, W., Standi, E., Schnell, O., Kragelund, C., Kober, L., Faber, J., Hildebrandt, P., Steffensen, R., Pankowska, E., Szypowska, A., Lipka, M., Herwig, J., Scholl-Schilling, G., Bohles, H., Robertson, K. J., Schonle, E., Gucev, Z., Mordhorst, L., Tamer, S. C., Gall, M-A, Ludvigsson, J., Hoogma, R. P. L., Hammond, P. J., Gomis, R., Kerr, D., Bruttomesso, D., Bouter, P., Wiefels, K. J., La Calle, H., Schweitzer, D. H., Pfohl, M., Torlone, E., Krinelke, L. G., 205-Nations Study Group, Conget, I., Storms, F., Rodriguez, J., Leperlier, C., Davies, M., At Lantus, Study Group, Peter, R., Luzio, S. D., Dunseath, G., Miles, A., Hare, B., Backx, K., Pauvaday, V., Owens, D. R., Caselli, A., Marfia, G. A., Battista, C., Veves, A., Spallone, V., Uccioli, L., Gonzalez, J. S., Peyrot, M. F., Rubin, R. R., Leventhal, H., Scheffler, N., Ulbrecht, J. S., Cavanagh, P. R., Boulton, A. J., Perrin, N. A., Oglesby, A., Bastyr, E. J., Ziegler, D., Siekierka-Kleiser, E., Meyer, B., Schweers, M., Selvarajah, D., Wilkinson, I. D., Emery, C. J., Shaw, P. J., Griffiths, P. D., Tesfaye, S., Obrosova, I. G., Arezzo, J., Phillips, K., Fidarestat Study Group, Gribble, F. M., Williams, L., Reimann, F., Iakoubov, R., Whiteside, C., Brubaker, P. L., Acitores, A., Gonzalez, N., Sancho, V., Valverde, I., Villanueva-Penacarrillo, M. L., Martin-Duce, A., Trigo, M. V., Arnes, L., Burkart, V., Ichino, N., Ohashi, A., Klein, B. S., Paxian, S., Schmid, R., Karlsen, A. E., Heding, P. E., Frobose, H., Ronn, S. G., Kruhoffer, M., Orntoft, T. F., Nerup, J., Mandrup-Poulsen, T., Billestrup, N., Cardozo, A. K., Ortis, F., Feng, Y-M, Rasschaert, J., Eylen, F., Storling, J., Herchuelz, A., Eizirik, D. 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F., Roggenland, D., Reinsen, B., Klein, H. H., Rittig, K., Stock, J., Kocher, B., Balletshofer, B., Lee, J., Shon, H. S., Chung, D. S., Nakatani, Y., Matsuhisa, M., Kaneto, H., Hatazaki, M., Yoshiuchi, K., Katakami, N., Kawamori, D., Ohtoshi, K., Sakamoto, K., Matsuoka, T-A, Ozawa, K., Ogawa, S., Hori, M., Yamasaki, Y., Zitouni, K., Harry, D., Nourooz-Zadeh, J., Betteridge, J. D., Earle, K. A., Rasmussen, L. M., Olesen, P., Franco, L., Corvaja, C., Semplicini, A., Rosen, P., Lee, I-K, Kim, M-J, Park, K-G, Jung, E-D, Shin, D-W, Jo, S-R, Obuobie, K., Prakash, P. K., Hanna, F. W., Evans, M., Lazarus, J., Varadhan, L., Gurushankar, J., James, D., Sheikh, S., Gaede, P., Li, H., Zou, D., Lee, S. J., Choi, M. G., Kim, D. S., Kim, T. W., Vilarrasa, N., Perez-Maraver, M., Mena, E., Perez, D., Setti, G., Buckingham, R., Urbancic, V., Stefanovska, A., Bernjak, A., Azman-Juvan, K., Kocijancic, A., Glowania, A., Filters, T. S., Fosmark, D. S., Torjesen, P. A., Kilhovd, B., Berg, T. 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35. Gilbert's syndrome and fluorouracil toxicity in colorectal cancer patients: which correlation?
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Mandalà, M., Cremonesi, M., Cazzaniga, M., Rezzani, C., Ghilardi, M., Mary, C., Ferretti, G., and Barni, S.
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GILBERT disease ,COLON cancer patients ,FLUOROURACIL - Abstract
A letter to the editor is presented in response to the article about Gilbert's syndrome in colorectal cancer patients in the previous issue.
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- 2015
36. Risk factors in medication-overuse headache: A 1-year follow-up study (care II protocol).
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Sances, G, Ghiotto, N, Galli, F, Guaschino, E, Rezzani, C, Guidetti, V, and Nappi, G
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HEADACHE treatment , *DETOXIFICATION (Substance abuse treatment) , *ALCOHOL drinking , *SMOKING , *PROGNOSIS ,DRUG overdose risk factors - Abstract
To investigate factors influencing prognosis in medication-overuse headache (MOH), we conducted a 12-month follow-up of patients with probable MOH. We recruited 215 patients consecutively admitted to our headache centre for an inpatient detoxification treatment. We analysed likely predictor factors for headache resolution (sex, age, primary headache, psychiatric comorbidity, type and timing of overuse). Mann–Whitney U-test and chi-squared test were used. One year after withdrawal, we had complete data on 172 patients (80%): 38 of these patients (22%) had relapsed into overuse and 134 (78%) had not. The negative prognostic factors for relapse were: intake of more than 30 doses/month (P ¼ 0.004), smoking (P¼ 0.012), alcohol consumption (P ¼ 0.037), non-confirmation of MOH diagnosis 2 months after detoxification (P ¼ 0.000), and return to overused drug(s) (P ¼ 0.000). The 1-year relapse rate was 22%. The existence of sub-groups of MOH patients with such risk factors could influence treatment strategies. [ABSTRACT FROM PUBLISHER]
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- 2010
- Full Text
- View/download PDF
37. Prevalence of patient-reported dysphagia in multiple sclerosis patients: an Italian multicenter study (using the DYMUS questionnaire)
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Claudio Solaro, Claudio Gasperini, Valentina Zipoli, C. Rezzani, Erika Trabucco, Pasquin Rossi, L. Finamore, Pietro Annovazzi, A. Ghezzi, M. L. Stromillo, Maria Pia Amato, Roberto Bergamaschi, Jessica Frau, Simona Bonavita, Davide Maimone, Marta Giannini, M. Rottoli, Emanuele D'Amico, Maria Grazia Grasso, Domenico A. Restivo, M. Della Corte, Lorena Lorefice, Emilio Portaccio, Francesco Patti, Solaro, C, Rezzani, C, Trabucco, E, Amato, Mp, Zipoli, V, Portaccio, E, Giannini, M, Patti, F, D'Amico, E, Frau, J, Lorefice, L, Bonavita, Simona, Corte, Md, Grasso, Mg, Finamore, L, Ghezzi, A, Annovazzi, P, Rottoli, M, Gasperini, C, Restivo, D, Maimone, D, Rossi, P, Stromillo, Ml, and Bergamaschi, R.
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Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Multiple Sclerosis ,Design data ,Adolescent ,Disease duration ,Statistics as Topic ,QUESTIONNAIRE ,Disease ,DYSPHAGIA ,Disease course ,Disability Evaluation ,Young Adult ,Surveys and Questionnaires ,otorhinolaryngologic diseases ,medicine ,Prevalence ,Humans ,Child ,business.industry ,Multiple sclerosis ,Infant ,Middle Aged ,medicine.disease ,Dysphagia ,Clinical Practice ,Cross-Sectional Studies ,Neurology ,Multicenter study ,Italy ,Child, Preschool ,Physical therapy ,Female ,Neurology (clinical) ,Self Report ,medicine.symptom ,business ,Deglutition Disorders - Abstract
OBJECTIVE: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) with a chronic course. Dysphagia represents one of the current challenges in clinical practice for the management of MS patients. Dysphagia starts to appear in mildly impaired MS subjects (EDSS 2-3) and becomes increasingly common in the most severely disabled subjects (EDSS 8-9). The aim of the present study was to evaluate the frequency and characteristics of patient-reported dysphagia in MS patients with a multicenter study using the recently developed DYMUS (DYsphagia in MUltiple Sclerosis) questionnaire. DESIGN: Data were collected in a multi-centre, cross-sectional study using a face-to-face structured questionnaire for clinical characteristics and the DYMUS questionnaire. RESULTS: 1875 patients were interviewed. The current study has shown a correlation between patient-reported dysphagia and EDSS and disease course but not with age, gender and disease duration. Questionnaires were divided into "patient-reported dysphagia-yes" (587, 31.3%) and "patient-reported dysphagia-no" (1288, 68.7%). Compared with the patient-reported dysphagia-no group, patients in patient-reported dysphagia-yes group had higher EDSS score (mean EDSS 4.6 vs. 2.8; p
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- 2012
38. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
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S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. Lindsay, M Christoforidou, A Abicht, E Harno, K Cyganek, A Fitchet, S Neelotpol, P Nikishin, P Serradas, J Hinrichsen, M Halvorson, M Chovatia, B Voet, Jinny Willis, E Parretti, M Haslbeck, M Wellard, L Teng, Julio Wainstein, J S Fischer, K. Lalic, D Roggenland, I Gich, R Anwar, Maurizio Cassader, D Serota, X J Li, R J Schotzinger, Vilmundur Gudnason, Björn Zethelius, S A Wootton, W Andrzejewski, R Rezsohazy, R Gao, T Klimentova, T Mazurek, I Bruckner, C Dohrmann, R E James, G daSilva Xavier, Kim S-Y., A Dorca, Stuart J. Pocock, Terri J. Allen, I Giovos, P B Parab, N H Andersen, P Fotinakis, Miriam Cnop, H Lee, Norbert Tennagels, Omorodola I. Abatan, F Ailett, I. Lager, D Manzella, H Hut, Larry A. Distiller, G Lip, Lim S-K., Rong Zhang, T Tsuno, Steen Knudsen, M. Bajardi, Manuel Benito, Dai Sugimoto, Melvin J. Prince, D W Dunstan, D Rankins, K A Majali, G Ozansoy, Isabella Russo, S Uçak, G Annuzzi, R Talar-Wojnarowska, K Lange, S Neugebauer-Baba, Campbell H. Thompson, Eric Renard, P. D. Mountjoy, Z Morrison, Elizabeth A. Davis, Franco Cavallo, C Corvaja, R Antuña, Craig John Currie, H Linnebjerg, He Y-L., A J Palmer, Mariola R. Chacón, H Malinska, M. Jones, R Lichnovská, K Mandes, Paolo Tessari, T Mokhort, A Laina, H. L. Y. Chan, I Schmidt, R Banks, Richard G. IJzerman, L Ksinantova, G Setti, H Vaudry, A Gallo, V Spallone, Chen J-W., Thomas Danne, A Chong, M Hallschmid, S Aczel, S Hulme, N Islam, M Hosoi, P M Ternan, P Di Bartolo, N Bishara, T Shibasaki, Martin A. Osterhoff, Im S-S., M Jecht, T Hamaguchi, S Mattera, K Ways, Elizabeth Northam, U Rajala, Reinhard W. Holl, L Yang, S Panaiotopoulos, K Horvath, R Kluge, Thora B. Bodvarsdottir, Y Dong, Irene Alemanno, C McDougall, Reimar W. Thomsen, M Campbell, W Rabl, John Öhrvik, Yuichiro Yamada, Paola Ungaro, W Benzer, Mike Sampson, Roberto Trevisan, R G Radu, Aas A-M., P E Lobo, Ricardo Scott, S M Son, Josephine M. Forbes, T A Hillier, K L Wyne, Louis L. 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Tuomilehto, J Hauptman, M Abdel-Ghany, D Lacombe, Toralph Ruge, Johannes A Maassen, Triantafyllos Didangelos, K Sasaki, I Argüelles, Klaus Levin, C Popow, Emanuel Christ, R Chetty, L Baillet-Blanco, Jo-Ann Salmon, T Mine, James L. Trevaskis, I Franke, J Gorski, E A Andrianova, A Dayan, A Caballero, Aleksandra Gilis-Januszewska, M Yasujima, Z Kasalová, C.D.A. Stehouwer, F. K. Gorus, G A Nichols, A Glowania, David P. Strachan, P Fredlund, N. F. da Silva, P Reboldi, M Sausbier, K H Groenier, G Stuccio, N Guttman, K R Ahmed, A D Ristic, T Kapellen, J Coutcher, Aldo V. Greco, Oswald Wagner, A Zagayko, Maria Alevizaki, B B Zhang, W F Ferris, Jenny Fredriksson, Lois Jovanovic, J Hänninen, R De Giglio, Kazuo Yagui, O Potterat, P Hamliton, R E Scranton, B Mankovsky, A Stylianou, B Fellström, Abdel-Wahab Yha., M Kitagawa, Katherine L. Baldock, F R Johnson, F Baigts, S D'Addato, F J Sanz, A Mistry, S D Wise, T Pratipanawatr, U R Fölsch, James R.C. 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Obrosova, J Fruchart, M Ilic, Björn Eliasson, Gilles Chatellier, M A Martín, D M Kendall, Holger Luthman, V F Varillas, D Maccubbin, Jang S-A., Amalia Gastaldelli, E Salzsieder, P. de Mol, A Yoshida, H D Lindner, D Gostiljac, M Just, Pan C-Y., J M Fujitaki, G Eiermann, K Bergenheim, A D Frick, A Agacdiken, K Varytimiadis, K Cseh, D A Jackson, S Calderari, Dena G. Hernandez, H M Liebich, K Min, F. de Zegher, Bernd Kulzer, K Han, Ulrich A. Müller, D Marrero, H Hatakeyama, René Koopman, Doo H-K., Petr Wohl, P. Sharp, P Forder, Thor Aspelund, N Meneveau, R M Schmülling, R Aubert, Thom Sam., H Youshikawa, M Ankelo, D Bowden, I Kelly, Frédéric Fumeron, M Sartini, Robert S. Sherwin, L Varadhan, A Criscimanna, John Betteridge, V Jelic, M Bartnik, N Lemke, B Ursø, A Bertoldo, A M Owona, H Okochi, L Pérez-Tamajó, S L Monfre, Daniel Brandhorst, K T Legg, Andries J. Smit, Veronica Sancho, Masashi Hirai, C Klein, Paul J. 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Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
- Subjects
0303 health sciences ,medicine.medical_specialty ,business.industry ,EASD ,Endocrinology, Diabetes and Metabolism ,Human physiology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Family medicine ,Internal Medicine ,Medicine ,business ,030217 neurology & neurosurgery ,030304 developmental biology - Published
- 2004
39. Validation of the Italian Version of the Dizziness Handicap Inventory, the Situational Vertigo Questionnaire, and the Activity-Specific Balance Confidence Scale for Peripheral and Central Vestibular Symptoms.
- Author
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Colnaghi S, Rezzani C, Gnesi M, Manfrin M, Quaglieri S, Nuti D, Mandalà M, Monti MC, and Versino M
- Abstract
Neurophysiological measurements of the vestibular function for diagnosis and follow-up evaluations provide an objective assessment, which, unfortunately, does not necessarily correlate with the patients' self-feeling. The literature provides many questionnaires to assess the outcome of rehabilitation programs for disequilibrium, but only for the Dizziness Handicap Inventory (DHI) is an Italian translation available, validated on a small group of patients suffering from a peripheral acute vertigo. We translated and validated the reliability and validity of the DHI, the Situational Vertigo Questionnaire (SVQ), and the Activities-Specific Balance Confidence Scale (ABC) in 316 Italian patients complaining of dizziness due either to a peripheral or to a central vestibular deficit, or in whom vestibular signs were undetectable by means of instrumental testing or clinical evaluation. Cronbach's coefficient alpha, the homogeneity index, and test-retest reproducibility, confirmed reliability of the Italian version of the three questionnaires. Validity was confirmed by correlation test between questionnaire scores. Correlations with clinical variables suggested that they can be used as a complementary tool for the assessment of vestibular symptoms. In conclusion, the Italian versions of DHI, SVQ, and ABC are reliable and valid questionnaires for assessing the impact of dizziness on the quality of life of Italian patients with peripheral or central vestibular deficit.
- Published
- 2017
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40. Validation of the Besta Neurological Institute rating scale for myasthenia gravis.
- Author
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Antozzi C, Brenna G, Baggi F, Camera G, Maggi L, Rezzani C, Montomoli C, and Mantegazza R
- Subjects
- Analysis of Variance, Disability Evaluation, Female, Humans, Male, Reproducibility of Results, Myasthenia Gravis diagnosis, Myasthenia Gravis physiopathology, Neurologic Examination methods
- Abstract
Introduction: We validated the scale for myasthenia gravis (MG) developed at the Neurological Institute Foundation of Milan (INCB-MG scale)., Methods: A total of 174 patients were evaluated with the INCB-MG and compared with the MG Composite (MGC) as the gold standard. Dimensionality, reliability, and validity of the INCB-MG scale were studied by principal component factor analysis, Cronbach alpha, and Pearson correlation coefficients; interobserver reliability was calculated by the weighted Cohen K coefficient., Results: Generalized and bulbar INCB-MG subscales were unidimensional with excellent consistency; the INCB-MG and MGC scales were strongly correlated. Fatigability assessment was correlated with the INCB-MG generalized, bulbar, and respiratory subscales., Conclusions: The INCB-MG scale is a reliable tool to assess MG and is strongly correlated with the MGC. The INCB-MG scale is a valid tool for every day practice and should be further investigated for its application in clinical trials., (© 2015 Wiley Periodicals, Inc.)
- Published
- 2016
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41. A new self-report quality of life questionnaire for children with neuromuscular disorders: presentation of the instrument, rationale for its development, and some preliminary results.
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Orcesi S, Ariaudo G, Mercuri E, Beghi E, Rezzani C, and Balottin U
- Subjects
- Adolescent, Case-Control Studies, Child, Child, Preschool, Feasibility Studies, Female, Humans, Male, Muscular Dystrophy, Duchenne psychology, Parents, Socioeconomic Factors, Neuromuscular Diseases psychology, Quality of Life, Self Report, Surveys and Questionnaires
- Abstract
Improvement of quality of life in neuromuscular disorders is a primary objective, both in management of affected children and in the context of therapeutic trials. Quality of life is a subjective concept and it is crucial to gather information directly from patients. We created the SOLE Questionnaire for NMDs, a new instrument designed to investigate quality of life in children with neuromuscular disorders, and tested it in a study population of 78 patients and in 81 healthy children aged 5 to 13 years. The SOLE Questionnaire, characterized by a visual and neutral approach, was well received, practical, rapid to administer, and able to discriminate between patients and controls. We also confirmed the presence of disagreement about children's quality of life between children and their parents. We suggest that our new approach could help to improve understanding of quality of life in children with neuromuscular disorders.
- Published
- 2014
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42. Duloxetine is effective in treating depression in multiple sclerosis patients: an open-label multicenter study.
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Solaro C, Bergamaschi R, Rezzani C, Mueller M, Trabucco E, Bargiggia V, Dematteis F, Mattioda A, Cimino V, Restivo D, Patti F, and Cavalla P
- Subjects
- Adrenergic Uptake Inhibitors adverse effects, Adult, Aged, Aged, 80 and over, Antidepressive Agents adverse effects, Diagnostic and Statistical Manual of Mental Disorders, Drug Monitoring, Duloxetine Hydrochloride, Fatigue etiology, Fatigue prevention & control, Female, Humans, Immunosuppressive Agents therapeutic use, Male, Middle Aged, Multiple Sclerosis drug therapy, Multiple Sclerosis physiopathology, Multiple Sclerosis, Relapsing-Remitting drug therapy, Multiple Sclerosis, Relapsing-Remitting physiopathology, Multiple Sclerosis, Relapsing-Remitting psychology, Nausea chemically induced, Patient Dropouts, Selective Serotonin Reuptake Inhibitors adverse effects, Thiophenes adverse effects, Adrenergic Uptake Inhibitors therapeutic use, Antidepressive Agents therapeutic use, Depression drug therapy, Multiple Sclerosis psychology, Selective Serotonin Reuptake Inhibitors therapeutic use, Thiophenes therapeutic use
- Abstract
Objectives: Duloxetine hydrochloride, a dual reuptake inhibitor of serotonin and norepinephrine, was evaluated for its therapeutic efficacy, safety, and tolerability in the treatment of depression in patients with multiple sclerosis (MS). Lifetime depression prevalence approaches 50% in MS patients. The aim of the study was to assess the safety and efficacy of duloxetine for treatment of depression in MS patients., Methods: An open-label study evaluated the efficacy of 12 weeks of duloxetine administration (maximal dose = 60 mg/d) in MS patients with clinical depression. The Beck scale score variation after 4 (T1) and 12 (T2) weeks of treatment was used for the primary outcome measurement, whereas secondary outcome was measured using the Modified Fatigue Impact Scale. Safety was evaluated by recording treatment-related adverse events, monitoring vital signs, and recording frequency and reasons for interruption or discontinuation of treatment., Results: Seventy-five patients were enrolled in the study. Sixty-three patients completed the study by continuing duloxetine treatment for 12 weeks (T2). Twelve subjects dropped out of the study because of adverse effects or noncompliance. Nausea was the most common adverse event reported. A significant reduction in the Beck Depression Inventory and Modified Fatigue Impact Scale scores, after both 4 and 12 weeks of therapy, was observed., Conclusions: The results suggest that duloxetine is well tolerated, safe, and effective in reducing depression and fatigue in MS patients.
- Published
- 2013
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43. Cross-cultural validation of a short form of the Oral Health Impact Profile for temporomandibular disorders.
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Segù M, Collesano V, Lobbia S, and Rezzani C
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- Adult, Facial Pain psychology, Female, Humans, Italy, Male, Quality of Life, Reproducibility of Results, Surveys and Questionnaires, Translations, Cross-Cultural Comparison, Sickness Impact Profile, Temporomandibular Joint Disorders psychology
- Abstract
Objectives: We set out to develop and validate an Italian version of the Oral Health Impact Profile Questionnaire (OHIP) that is appropriate for use in temporomandibular disorders (TMD)., Methods: At first, we had the questionnaire translated from English into Italian by three bilingual individuals whose mother tongue was Italian and thus had three different versions of the questionnaire. These were translated back into English by a native English speaker and the version closest to the original English OHIP was selected. The validation of a questionnaire generally involves the study of the psychometric properties of the instrument: its validity and reliability. Before studying these properties, we assessed the factorial structure of the questionnaire., Results: The number of eigenvalues >1, computed by exploratory factor analysis, was seven. The percentage of cumulative variability explained by a model with six dimensions is 66, whereas that explained by a model with seven dimensions is 70. Therefore, considering that the increment of explained variability due to the seventh dimension is low (3.68%) and that the seventh eigenvalue is very close to 1, we considered a six-factor model capable of explaining the factorial structure of the data. Content analysis suggested eliminating the item 'Felt Self-conscious', as most of the subjects did not understand its meaning. Spearman correlation coefficients showed an association between the scores of all the different subscales and the variable for pain. All the coefficients were significantly different from 0 (P < 0.05). Cronbach's alpha value, always >0.70, showed quite a good reliability for each of the six subscales., Conclusions: These results reveal a reasonable degree of cross-cultural consistency between the two versions of the OHIP, and thus indicate that our Italian version is valid.
- Published
- 2005
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44. Evaluation of the efficacy of the Italian guidelines on COPD: a cluster randomized trial.
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Tinelli C, Rezzani C, Biino G, Marinoni A, Rossi A, Volpini E, Pistorio A, Termini R, and Grassi M
- Subjects
- Aged, Female, Follow-Up Studies, Humans, Italy, Male, Middle Aged, Prospective Studies, Quality of Life, Treatment Outcome, Practice Guidelines as Topic standards, Pulmonary Disease, Chronic Obstructive therapy
- Abstract
Background: Chronic Obstructive Pulmonary Disease (COPD) is a profoundly disabling disease managed predominantly by General Practitioners (GPs). We planned this prospective trial to evaluate the applicability of Italian GP-directed guidelines in routine practice and whether adherence to them improves treatment efficacy, with respect to decreased exacerbations, hospital admissions, drug use, and out-patient appointments and improved quality of life (QoL)., Methods: In a cluster randomised trial, 22 GPs were randomly put into two groups: one group was asked to follow the guidelines (YES-GL), the other to continue normal clinical practice (NO-GL). These GPs enrolled 123 patients with COPD and followed them for one year., Results: Patients managed by the YES-GL GPs had more outpatient appointments and specialist consultations and a higher probability of being classified as having severe COPD. The QoL was fairly low in both groups, and all other clinical outcomes taken into consideration, were not affected by application of the guidelines., Conclusion: The guidelines did not substantially alter the clinical evolution of COPD patients, even though some facets of management improved.
- Published
- 2003
45. Asthma-like symptoms assessment through ECRHS screening questionnaire scoring.
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Grassi M, Rezzani C, Biino G, and Marinoni A
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- Adult, Europe epidemiology, European Union, Female, Health Surveys, Humans, Immunoglobulin E blood, Male, Prevalence, ROC Curve, Reproducibility of Results, Sensitivity and Specificity, Skin Tests, Asthma diagnosis, Asthma epidemiology, Mass Screening methods, Surveys and Questionnaires
- Abstract
The definition of asthma has always been a matter of discussion. The European Community Respiratory Health Survey (ECRHS) is a multinational survey designed to compare the prevalence of asthma in subjects aged 20 to 44 years throughout European countries. In each center a representative sample completed a self-administered screening questionnaire composed of nine dichotomous items. We propose a method for constructing a score for the ECRHS screening questionnaire and we validate the method with reference to the clinical diagnosis available for the Italian centers. Clinical diagnosis was made by a group of medical experts after examining the responses to a standardized clinical interview, respiratory function tests, and allergy tests. Before constructing a summary score, the number of latent factors/dimensions explaining correlations among the observed items was recognized. We identified only one factor/dimension underlying the screening questionnaire, so a summary score was determined by the Homogeneity Analysis by Alternating Least Square (HOMALS). Using best Receiver Operating Characteristic (ROC) threshold the diagnostic test of the score had sensitivity and specificity of 75.1 and 80.1%, respectively. The method of scoring is easily reproducible, and has the advantage of optimizing information recoded by the questionnaire.
- Published
- 2003
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46. Vinorelbine and carboplatin in inoperable non-small cell lung cancer: a monoinstitutional phase II study.
- Author
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Cremonesi M, Mandalà M, Cazzaniga M, Rezzani C, Gambera M, and Barni S
- Subjects
- Adult, Aged, Aged, 80 and over, Antineoplastic Agents, Phytogenic administration & dosage, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Antineoplastic Combined Chemotherapy Protocols adverse effects, Carboplatin administration & dosage, Carcinoma, Non-Small-Cell Lung secondary, Drug Administration Schedule, Female, Humans, Lung Neoplasms pathology, Male, Middle Aged, Neoplasm Staging, Survival Analysis, Treatment Outcome, Vinblastine administration & dosage, Vinorelbine, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma, Non-Small-Cell Lung drug therapy, Lung Neoplasms drug therapy, Vinblastine analogs & derivatives
- Abstract
Chemotherapy regimens for patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) provide typically palliation or limited symptom-free survival. We investigated the efficacy, in terms of response rate and time to progression, of a combination chemotherapy containing carboplatin and vinorelbine as a first-line treatment for inoperable NSCLC. Fifty-two consecutive patients with advanced NSCLC were treated with carboplatin AUC 6 according to Calvert's formula on day 1, combined with vinorelbine, 25 mg/m(2) on days 1 and 8. Therapy was given every 3 weeks. The median age was 66 years (range, 40-80); ECOG performance status was 0 in 20, 1 in 25 and 2 in 7 patients. According to an intent-to-treat analysis, response rate (partial and complete responses) in 52 assessable patients was 18/52 (34.6%; 95% confidence interval, 22-47%). In addition, 16 patients (30.8%) had stable disease and 18/52 (34.6%; 95% CI, 22-47%) progressed while on treatment. Median time to progression and overall survival were 7, 5 and 12.3 months, respectively. Grade 3/4 granulocytopenia was observed in 18/8 patients (34.6/15.4%). Grade 3/4 nadirs generally lasted no more than 7 days, and no neutropenic fever was reported. The treatment was generally very well tolerated: grade 1 or 2 nausea and vomiting was observed in 12 and 4 patients, respectively, and grade 2 neuropathy in 5% of cases. Statistical analysis did not highlight any significant differences in clinical benefit (partial and complete responses and stable disease), time to progression, or grade 3-4 hematologic and non-hematological toxicity according to age (
65 years). Carboplatin AUC 6 and vinorelbine was found to be an efficacious regimen as a first-line treatment for inoperable lung cancer patients and was also subjectively very well tolerated in aged patients. The regimen warrants further investigation in the emerging subgroup of aged patients in order to draw firm conclusions., (Copyright 2003 S. Karger AG, Basel) - Published
- 2003
- Full Text
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47. ECRHS screening questionnaire scoring: a methodological suggestion for asthma assessment. European Community Health Survey.
- Author
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Biino G, Rezzani C, Grassi M, and Marinoni A
- Subjects
- Adult, Data Interpretation, Statistical, Humans, Italy epidemiology, Prevalence, Risk Factors, Sensitivity and Specificity, Asthma epidemiology, Mass Screening, Surveys and Questionnaires
- Abstract
Univocal definition and classification of Asthma have always been a matter of discussion, and that is reflected in the difficulty of constructing a measure of pathology severity. The European Community Health Survey is a multinational survey designed to compare the prevalence of asthma in subjects, aged 20 to 44 years, in several European areas. In each participating center a sample of 3000 adults filled a self-administered screening questionnaire composed by 9 dichotomous items. Aim of the present study is to investigate unidimensionality of the ECRHS screening questionnaire and to determine and validate a scoring of asthma-like symptoms seriousness. Dimensionality and scoring was determined through a Homogeneity Analysis by Alternating Least Square; while scoring validation was assessed by a cross validation technique. This study found the existence of a sole dimension underlying the screening questionnaire; furthermore a scoring of asthma-like symptoms seriousness was determined with the indication of a cut-off in order to distinguish between asthma symptomatic and non symptomatic subjects.
- Published
- 2000
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