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241 results on '"Reznicek, Gottfried"'

10. Plant extracts in cell-based anti-inflammatory assays—Pitfalls and considerations related to removal of activity masking bulk components

Author

Picker, Paolo, Vogl, Sylvia, McKinnon, Ruxandra, Mihaly-Bison, Judit, Binder, Markus, Atanasov, Atanas G., Fakhrudin, Nanang, Grzywacz, Anna M., Heiss, Elke H., Zehl, Martin, Saukel, Johannes, Wawrosch, Christoph, Schinkovitz, Andreas, Waltenberger, Birgit, Bauer, Rudolf, Rollinger, Judith M., Stuppner, Hermann, Dirsch, Verena M., Bochkov, Valery N., Reznicek, Gottfried, and Kopp, Brigitte

Published
2014
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12. Workflow development for the analysis of phenolic compounds in wine using liquid chromatography combined with drift-tube ion mobility-mass spectrometry

Author

Causon, Tim J., Dosen, Marian, Reznicek, Gottfried, and Hann, Stephan

Subjects
Chemistry
Abstract

Here we propose an exemplary workflow for the analysis of phenolic components in wine enabling confident differential analysis using high performance liquid chromatography (HPLC) in combination with low-field drift-tube ion [...]

Published
2016

14. Biosynthetic Potential of the Endophytic Fungus Helotiales sp. BL73 Revealed via Compound Identification and Genome Mining

Author

Oberhofer, Martina, primary, Malfent, Fabian, additional, Zehl, Martin, additional, Urban, Ernst, additional, Wackerlig, Judith, additional, Reznicek, Gottfried, additional, Vignolle, Gabriel A., additional, Rückert, Christian, additional, Busche, Tobias, additional, Wibberg, Daniel, additional, and Zotchev, Sergey B., additional

Published
2022
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33. Antimicrobial and antioxidant properties of Artemisia L. species from western Anatolia

Author

EREL, Şüra BAYKAN, REZNICEK, Gottfried, and ŞENOL, Serdar Gökhan

Subjects
Key words: Artemisia,essential oil,antimicrobial activity,antioxidant activity
Abstract

Artemisia L. taxa (A. absinthium L., A. arborescens L., A. campestris L., A. scoparia Waldst. & Kit., A. santonicum L., and A. vulgaris L.) naturally distributed through western and southwestern Turkey were chosen as experimental materials in this study. Essential oils of the aerial parts of these Artemisia species were isolated by hydrodistillation and analyzed by gas chromatography-mass spectrometry. The major components were identified as sabinene in A. absinthium (17.56%), camphor in A. arborescens (33.39%), 1,2-dehydro acenaphthylene in A. campestris and A. scoparia (20.71% and 11.80%, respectively), and a-thujone in A. vulgaris and A. santonicum (56.13% and 39.46%, respectively). Essential oils and methanolic extracts of the plants were tested for antimicrobial activity using the disk-diffusion method against 8 bacteria and 1 fungus. Staphylococcus aureus was the most sensitive bacteria to all of the essential oils. A. santonicum and A. scoparia were the most active plants against Candida albicans, with 35-mm and 40-mm diameter zones, respectively. Antioxidant capacities of the plants were also tested. The radical scavenging activity of A. scoparia extract (48.51%) and essential oil (80.08%), the Trolox equivalent antioxidant capacity of A. campestris extract (10.76 ± 0.47), and the a-tocopherol equivalent of A. absinthium extract (5.87 ± 0.17) were the highest results.

Published
2014

35. Addendum: Šarić-Kundalić, B.; Fialová, S.; Dobeš, C.; Ölzant, S.; Tekeľová, D.; Grančai, D.; Reznicek, G.; Saukel, J. Multivariate Numerical Taxonomy of Mentha Species, Hybrids, Varieties and Cultivars. Sci. Pharm. 2009, 77, 851–876

Author

Šarić-Kundalić, Broza, primary, Fialová, Silvia, additional, Dobeš, Christoph, additional, Ölzant, Silvester, additional, Tekeľová, Daniela, additional, Grančai, Daniel, additional, Reznicek, Gottfried, additional, and Saukel, Johannes, additional

Published
2016
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37. An Open, Randomized, Single-Center, Crossover Pharmacokinetic Study of Meropenem after Intraperitoneal and Intravenous Administration in Patients Receiving Automated Peritoneal Dialysis

Author

Wiesholzer, Martin, primary, Pichler, Petra, additional, Reznicek, Gottfried, additional, Wimmer, Michaela, additional, Kussmann, Manuel, additional, Balcke, Peter, additional, Burgmann, Heinz, additional, Zeitlinger, Markus, additional, and Poeppl, Wolfgang, additional

Published
2016
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38. Influence of different peritoneal dialysis fluids on the in vitro activity of fosfomycin against <italic>Escherichia coli</italic>, <italic>Staphylococcus aureus</italic>, <italic>Staphylococcus epidermidis</italic>, <italic>and Pseudomonas aeruginosa</italic>

Author

Kussmann, Manuel, Hauer, Stefan, Burgmann, Heinz, Poeppl, Wolfgang, Pichler, Petra, Wiesholzer, Martin, Reznicek, Gottfried, and Zeitlinger, Markus

Subjects
ANTIBIOTICS, INFECTION, PERITONEAL dialysis, PERITONITIS, PSEUDOMONAS aeruginosa
Abstract

Peritonitis is still the main infectious complication among patients on peritoneal dialysis. For treatment of peritoneal dialysis-related peritonitis, the intraperitoneal administration of antibiotics admixed to peritoneal dialysis fluids (PDFs) should be preferred. However, the influence of diverse PDFs on the activity of frequently used antibiotics has been investigated insufficiently. Thus, the present study set out to investigate the in vitro activity of fosfomycin against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, and Staphylococcus aureus in commercially available PDFs. Time-kill curves in four different PDFs (Dianeal®, Extraneal®, Nutrineal®, and Physioneal®) were performed over 24 h with two different concentrations of fosfomycin (150 and 400 mg/L) and without antibiotics as control. Cation-adjusted Mueller Hinton broth (CA-MHB) was used as a comparator solution. In blank PDFs, bacterial growth of each organism evaluated was reduced when compared to CA-MHB. For S. aureus in blank Physioneal®, a reduction under the limit of detection was observed within 24 h. The activity of fosfomycin was reduced in all PDFs when compared to CA-MHB except for P. aeruginosa in Nutrineal® where the activity of fosfomycin was increased when investigated at 400 mg/L. Against E.coli, bactericidal activity was demonstrated in Extraneal®, Nutrineal®, and Physioneal®. Fosfomycin resistance (MIC > 1024 mg/L) was observed for P. aeruginosa in CA-MHB at both concentrations and in Nutrineal® at 150 mg/L. Fosfomycin is active in PDFs particularly against the frequently isolated enterobacterium E. coli. The choice of the respective PDF considerably influences the microbiological outcome in vitro. Further studies are warranted to investigate the clinical relevance of these findings. [ABSTRACT FROM AUTHOR]

Published
2018
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40. Efficacy of Fosfomycin Compared to Vancomycin in Treatment of Implant-Associated Chronic Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats

Author

Poeppl, Wolfgang, primary, Lingscheid, Tilman, additional, Bernitzky, Dominik, additional, Schwarze, Uwe Y., additional, Donath, Oliver, additional, Perkmann, Thomas, additional, Kozakowski, Nicolas, additional, Plasenzotti, Roberto, additional, Reznicek, Gottfried, additional, and Burgmann, Heinz, additional

Published
2014
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42. Quality Control of Valerianae Radix by Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) Spectroscopy.

Author

Nikzad-Langerodi, Ramin, Arth, Katharina, Klatte-Asselmeyer, Valerie, Bressler, Sabine, Saukel, Johannes, Reznicek, Gottfried, and Dobeš, Christoph

Subjects
DISCRIMINANT analysis, ESSENTIAL oils, GAS chromatography, HERBAL medicine, INFRARED spectroscopy, CHINESE medicine, MOLECULAR structure, QUALITY control, RESEARCH funding, VALERIANA officinalis, DATA analysis software, DESCRIPTIVE statistics, IN vitro studies
Abstract

(Acetoxy-)valerenic acid and total essential oil content are important quality attributes of pharmacy grade valerian root (Valerianae radix). Traditional analysis of these quantities is time-consuming and necessitates (harmful) solvents. Here we investigated an application of attenuated total reflection Fourier transform infrared spectroscopy for extractionless analysis of these quality attributes on a representative sample comprising 260 wild-crafted individuals covering the Central European taxonomic diversity of the Valeriana officinalis L.s. l. species aggregate with its three major ploidy cytotypes (i.e., di-, tetra- and octoploid). Calibration models were built by orthogonal partial least squares regression for quantitative analysis of (acetoxy-)valerenic acid and total essential oil content. For the latter, we propose a simplistic protocol involving apolar extraction followed by gas chromatography as a reference method for multivariate calibration in order to handle the analysis of samples taken from individual plants. We found good predictive ability of chemometric models for quantification of valerenic acid, acetoxyvalerenic acid, total sesquiterpenoid acid, and essential oil content with a root mean squared error of cross-validation of 0.064, 0.043, and 0.09 and root mean squared error of prediction of 0.066, 0.057, and 0.09 (% content), respectively. Orthogonal partial least squares discriminant analysis revealed good discriminability between the most productive phenotype (i.e., the octoploid cytotype) in terms of sesquiterpenoid acids, and the less productive ones (i.e., di- and tetraploid). All in all, our results demonstrate the application of attenuated total reflection Fourier transform infrared spectroscopy for rapid, extractionless estimation of the most important quality attributes of valerian root and minimally invasive identification of the most productive phenotype in terms of sesquiterpenoid acids. [ABSTRACT FROM AUTHOR]

Published
2018
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44. Ethnopharmacological in vitro studies on Austria's folk medicine—An unexplored lore in vitro anti-inflammatory activities of 71 Austrian traditional herbal drugs

Author

Vogl, Sylvia, primary, Picker, Paolo, additional, Mihaly-Bison, Judit, additional, Fakhrudin, Nanang, additional, Atanasov, Atanas G., additional, Heiss, Elke H., additional, Wawrosch, Christoph, additional, Reznicek, Gottfried, additional, Dirsch, Verena M., additional, Saukel, Johannes, additional, and Kopp, Brigitte, additional

Published
2013
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