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15 results on '"Restivo, Francesco M."'

4. Validation and Ecological Niche Investigation of a New Fungal Intraspecific Competitor as a Biocontrol Agent for the Sustainable Containment of Aflatoxins on Maize Fields

Author

Spadola, Giorgio, primary, Giannelli, Gianluigi, additional, Magagnoli, Serena, additional, Lanzoni, Alberto, additional, Albertini, Marco, additional, Nicoli, Riccardo, additional, Ferrari, Roberto, additional, Burgio, Giovanni, additional, Restivo, Francesco M., additional, and Degola, Francesca, additional

Published
2022
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6. The AFLATOX® Project: Approaching the Development of New Generation, Natural-Based Compounds for the Containment of the Mycotoxigenic Phytopathogen Aspergillus flavus and Aflatoxin Contamination

Author

Montalbano, Serena, primary, Degola, Francesca, additional, Bartoli, Jennifer, additional, Bisceglie, Franco, additional, Buschini, Annamaria, additional, Carcelli, Mauro, additional, Feretti, Donatella, additional, Galati, Serena, additional, Marchi, Laura, additional, Orsoni, Nicolò, additional, Pelosi, Giorgio, additional, Pioli, Marianna, additional, Restivo, Francesco M., additional, Rogolino, Dominga, additional, Scaccaglia, Mirco, additional, Serra, Olga, additional, Spadola, Giorgio, additional, Viola, Gaia C. V., additional, Zerbini, Ilaria, additional, and Zani, Claudia, additional

Published
2021
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8. Double Gamers—Can Modified Natural Regulators of Higher Plants Act as Antagonists against Phytopathogens? The Case of Jasmonic Acid Derivatives

Author

Orsoni, Nicolò, primary, Degola, Francesca, additional, Nerva, Luca, additional, Bisceglie, Franco, additional, Spadola, Giorgio, additional, Chitarra, Walter, additional, Terzi, Valeria, additional, Delbono, Stefano, additional, Ghizzoni, Roberta, additional, Morcia, Caterina, additional, Jamiołkowska, Agnieszka, additional, Mielniczuk, Elżbieta, additional, Restivo, Francesco M., additional, and Pelosi, Giorgio, additional

Published
2020
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14. The AFLATOX ® Project: Approaching the Development of New Generation, Natural-Based Compounds for the Containment of the Mycotoxigenic Phytopathogen Aspergillus flavus and Aflatoxin Contamination.

Author

Montalbano, Serena, Degola, Francesca, Bartoli, Jennifer, Bisceglie, Franco, Buschini, Annamaria, Carcelli, Mauro, Feretti, Donatella, Galati, Serena, Marchi, Laura, Orsoni, Nicolò, Pelosi, Giorgio, Pioli, Marianna, Restivo, Francesco M., Rogolino, Dominga, Scaccaglia, Mirco, Serra, Olga, Spadola, Giorgio, Viola, Gaia C. V., Zerbini, Ilaria, and Zani, Claudia

Subjects
AFLATOXINS, ASPERGILLUS flavus, FEED contamination, FOOD contamination, GENETIC toxicology, CORN disease & pest control, THIOSEMICARBAZONES, SHELF-life dating of food
Abstract

The control of the fungal contamination on crops is considered a priority by the sanitary authorities of an increasing number of countries, and this is also due to the fact that the geographic areas interested in mycotoxin outbreaks are widening. Among the different pre- and post-harvest strategies that may be applied to prevent fungal and/or aflatoxin contamination, fungicides still play a prominent role; however, despite of countless efforts, to date the problem of food and feed contamination remains unsolved, since the essential factors that affect aflatoxins production are various and hardly to handle as a whole. In this scenario, the exploitation of bioactive natural sources to obtain new agents presenting novel mechanisms of action may represent a successful strategy to minimize, at the same time, aflatoxin contamination and the use of toxic pesticides. The Aflatox® Project was aimed at the development of new-generation inhibitors of aflatoxigenic Aspergillus spp. proliferation and toxin production, through the modification of naturally occurring molecules: a panel of 177 compounds, belonging to the thiosemicarbazones class, have been synthesized and screened for their antifungal and anti-aflatoxigenic potential. The most effective compounds, selected as the best candidates as aflatoxin containment agents, were also evaluated in terms of cytotoxicity, genotoxicity and epi-genotoxicity to exclude potential harmful effect on the human health, the plants on which fungi grow and the whole ecosystem. [ABSTRACT FROM AUTHOR]

Published
2021
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15. Validation and Ecological Niche Investigation of a New Fungal Intraspecific Competitor as a Biocontrol Agent for the Sustainable Containment of Aflatoxins on Maize Fields

Author

Giorgio Spadola, Gianluigi Giannelli, Serena Magagnoli, Alberto Lanzoni, Marco Albertini, Riccardo Nicoli, Roberto Ferrari, Giovanni Burgio, Francesco M. Restivo, Francesca Degola, Spadola, Giorgio, Giannelli, Gianluigi, Magagnoli, Serena, Lanzoni, Alberto, Albertini, Marco, Nicoli, Riccardo, Ferrari, Roberto, Burgio, Giovanni, Restivo, Francesco M, and Degola, Francesca

Subjects
Microbiology (medical), intraspecific biocompetition, niche variation, food and beverages, Plant Science, aflatoxin biocontrol, Aspergillus flavu, Ecology, Evolution, Behavior and Systematics, Aspergillus flavus, maize protection
Abstract

Crop yield and plant products quality are directly or indirectly affected by climate alterations. Adverse climatic conditions often promote the occurrence of different abiotic stresses, which can reduce or enhance the susceptibility to pests or pathogens. Aflatoxin producing fungi, in particular, whose diffusion and deleterious consequences on cereals commodities have been demonstrated to highly depend on the temperature and humidity conditions that threaten increasingly larger areas. Biological methods using intraspecific competitors to prevent fungal development and/or toxin production at the pre-harvest level are particularly promising, even if their efficacy could be affected by the ecological interaction within the resident microbial population. A previously characterized Aspergillus flavus atoxigenic strain was applied in two maize fields to validate its effectiveness as a biocontrol agent against aflatoxin contamination. At one month post-application, at the harvest stage, its persistence within the A. flavus population colonizing the maize kernels in the treated area was assessed, and its efficacy was compared in vitro with a representation of the isolated atoxigenic population. Results proved that our fungal competitor contained the aflatoxin level on maize grains as successfully as a traditional chemical strategy, even if representing less than 30% of the atoxigenic strains re-isolated, and achieved the best performance (in terms of bio-competitive potential) concerning endogenous atoxigenic isolates.

Published
2022

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