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Summary: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy.

Summary: To celebrate its 10th anniversary, the prestigious journal Cells launched a series of Special Issues in 2021. The Special Issue entitled "10th Anniversary of Cells-Advances in Cell Cycle" was launched together with other sister Special Issues under the umbrella "10th Anniversary of Cells." The cell cycle is a series of events that drives cells to divide and produce two new daughter cells. The typical cell cycle in eukaryotes is composed of the following phases: G1, S, G2, and M phases. Cell cycle progression is mediated by cyclin-dependent kinases (CDKs) and their regulatory cyclin subunits. CDKs, such as CDK4/6, CDK2, and CDK1 (also known as CDC2), are serine/threonine kinases with a wide variety of substrates. CDKs are activated mainly by binding to their cyclin partners, whose expressions rise and fall throughout the cell cycle to mediate the temporal activation of each CDKs. Various cell cycle checkpoints exist to ensure that critical processes are engaged prior to progression to the next phase. These cell cycle checkpoints are the G1 (restriction) checkpoint, the G2/M DNA damage checkpoint, and the spindle assembly checkpoint (SAC).This Special Issue attracted the attention of many scientists in the cell cycle field and consists of 10 high quality papers, including four research articles and six scientific reviews: a great success. The four research articles focus on various important topics of the cell cycle using a broad range of model organisms, including yeast, sea urchins, green algae, and human cancer cell lines.

Summary: This book is a collection of original research articles in the field of computer-aided drug design. It reports the use of current and validated computational approaches applied to drug discovery as well as the development of new computational tools to identify new and more potent drugs.

Summary: This book presents a collection of works published in a recent Special Issue (SI) entitled "Computational Fluid Dynamics". These works address the development and validation of existent numerical solvers for fluid flow problems and their related applications. They present complex nonlinear, non-Newtonian fluid flow problems that are (in some cases) coupled with heat transfer, phase change, nanofluidic, and magnetohydrodynamics (MHD) phenomena. The applications are wide and range from aerodynamic drag and pressure waves to geometrical blade modification on aerodynamics characteristics of high-pressure gas turbines, hydromagnetic flow arising in porous regions, optimal design of isothermal sloshing vessels to evaluation of (hybrid) nanofluid properties, their control using MHD, and their effect on different modes of heat transfer. Recent advances in numerical, theoretical, and experimental methodologies, as well as new physics, new methodological developments, and their limitations are presented within the current book. Among others, in the presented works, special attention is paid to validating and improving the accuracy of the presented methodologies. This book brings together a collection of inter/multidisciplinary works on many engineering applications in a coherent manner.

Summary: The present book contains all of the articles that were accepted and published in the Special Issue of MDPI's journal Mathematics titled "Computational Intelligence and Human-Computer Interaction: Modern Methods and Applications". This Special Issue covered a wide range of topics connected to the theory and application of different computational intelligence techniques to the domain of human-computer interaction, such as automatic speech recognition, speech processing and analysis, virtual reality, emotion-aware applications, digital storytelling, natural language processing, smart cars and devices, and online learning. We hope that this book will be interesting and useful for those working in various areas of artificial intelligence, human-computer interaction, and software engineering as well as for those who are interested in how these domains are connected in real-life situations.

Summary: Nutrition, often along with physical activity, is by now acknowledged as a cornerstone in the prevention and even more so the treatment of many diseases. Indeed, food and nutritional intake nowadays are often thought to be the main source of wellbeing sometimes over- but also underestimating the impact of nutritional intake, dietary pattern and food-derived natural compounds in their impact on human health. In this Special Issue entitled `Clinical Nutrition: Recent Advances and Remaining Challenges´ a broad overview and summary on recent findings in various fields of clinical nutrition with special focus on chronic and degenerative diseases like metabolic diseases, cancers, neurodegenerative diseases, inflammatory bowel diseases, sarcopenia but also malnutrition in elderly, infants and children is provided. Nutrition, often along with physical activity, is by now acknowledged as a cornerstone in the prevention and even more so the treatment of many diseases. Indeed, food and nutritional intake nowadays are often thought to be the main source of wellbeing sometimes over- but also underestimating the impact of nutritional intake, dietary pattern and food-derived natural compounds in their impact on human health. In this Special Issue entitled `Clinical Nutrition: Recent Advances and Remaining Challenges´ a broad overview and summary on recent findings in various fields of clinical nutrition with special focus on chronic and degenerative diseases like metabolic diseases, cancers, neurodegenerative diseases, inflammatory bowel diseases, sarcopenia but also malnutrition in elderly, infants and children is provided.

Summary: This book is a collection of all papers published in the Special Issue "Coastal Vulnerability and Mitigation Strategies: From Monitoring to Applied Research". The main focus is to provide the state-of-the-art and recent research updates on sustainable management strategies for protecting vulnerable coastal areas. Based on 28 contributions from authors representing 17 different countries (Australia, China, Ecuador, Germany, Greece, India, Italy, Mexico, The Netherlands, New Zealand, Poland, Spain, Sri Lanka, Taiwan, United Arab Emirates, UK, USA), an ensemble of interdisciplinary articles has been collected, emphasizing the importance of tackling technical and scientific problems at different scales and from different point of views.

Summary: Caffeine is present in coffee and many other beverages and is the most widely used central nervous system stimulant. Coffee drinking or caffeine supplementation may have a role in preventing cardiometabolic and endocrine disease, neuroinflammation, cancer, and even all-cause mortality. Other aspects are either less known or controversial, including the effects on the brain-gut axis, neurodevelopment, behavior, pain, muscle-skeletal health, skin or sexual function. Studies focusing on special populations (neonates, children, adolescents, athletes, elderly, pregnant and nonpregnant women), or interactions with other drugs and foods, are relatively scarce but of obvious interest. Other compounds present in coffee and other caffeinated food stuffs may affect caffeine´s physiological effects with a tremendous impact on health. This Special Issue, which contains twenty-one manuscripts, has focused on some of these varied topics, providing further evidence of the multiple health benefits that coffee/caffeine intake may exert in humans, at least in specific populations (with a particular genetic profile or suffering from specific diseases). However, the specific effects in the different organs and systems, as well as the mechanisms involved are not yet clear. Furthermore, within the current context aiming to sustainable development, the coffee plant Coffee sp. and its so-far relatively neglected by-products are expected to become soon a source of ingredients for new functional foods whose properties will need to be precisely determined. We hope the readers of this Special Issue will find inspiration for new studies on the topic.

Summary: The prevalence of overweight and obesity has significantly increased over the past few decades and is linked to metabolic diseases across the lifespan. Its etiology has been attributed to a large number of sociodemographic, behavioral (e.g. unhealthy nutrition, low levels of physical activity), perinatal, and clinical risk factors, which are active already from childhood and adolescence. Still, their exact role, interplay, and mechanisms implicated in this process remain unclear. The trends of childhood obesity call for actions regarding the prevention and management of this disease early in life. The Special Issue "Childhood Obesity: Nutrition and Lifestyle Determinants, Prevention and Management" aims to host original articles, systematic reviews or meta- analyses that will advance the current knowledge on the role of health behaviors, especially of nutrition, on the development of overweight or obesity in childhood and adolescence, provide valuable information about the nutritional habits of overweight/obese children and adolescents, and describe novel approaches via lifestyle modification for the prevention or management of obesity in youth.

Summary: This book is a collection of the articles published the Special Issue of ISPRS International Journal of Geo-Information on "Citizen Science and Geospatial Capacity Building". The articles cover a wide range of topics regarding the applications of citizen science from a geospatial technology perspective. Several applications show the importance of Citizen Science (CitSci) and volunteered geographic information (VGI) in various stages of geodata collection, processing, analysis and visualization; and for demonstrating the capabilities, which are covered in the book. Particular emphasis is given to various problems encountered in the CitSci and VGI projects with a geospatial aspect, such as platform, tool and interface design, ontology development, spatial analysis and data quality assessment. The book also points out the needs and future research directions in these subjects, such as; (a) data quality issues especially in the light of big data; (b) ontology studies for geospatial data suited for diverse user backgrounds, data integration, and sharing; (c) development of machine learning and artificial intelligence based online tools for pattern recognition and object identification using existing repositories of CitSci and VGI projects; and (d) open science and open data practices for increasing the efficiency, decreasing the redundancy, and acknowledgement of all stakeholders.

Summary: Unravelling an intricate network of interatomic interactions and their relations to different behaviors of chemical compounds is key to the successful design of new materials for both existing and novel applications, from medicine to innovative concepts of molecular electronics and spintronics. X-ray crystallography has proven to be very helpful in addressing many important chemical problems in modern materials science and biosciences. Intertwined with computational techniques, it provides insights into the nature of chemical bonding and the physicochemical properties (including optical, magnetic, electrical, mechanical, and others) of crystalline materials, otherwise accessible by experimental techniques that are not so readily available to chemists. In addition to the advanced approaches in charge density analysis made possible by X-ray diffraction, the information collected over the years through this technique (which is easily mined from huge databases) has tremendous use in the design of new materials for medicine, gas storage, and separation applications as well as for electronic devices. This Special Issue contains two reviews and five articles that cover very different aspects of 'composition-structure' and 'structure-property' relations identified by X-ray diffraction and complementary techniques (from conventional IR and Raman spectroscopies to cutting-edge quantum chemical calculations) and their use in crystal engineering and materials science.

Summary: Cellulose empowers measurement science and technology with a simple, low-cost, and highly transformative analytical platform. This book helps the reader to understand and build an overview of the state of the art in cellulose-based (bio)sensing, particularly in terms of the design, fabrication, and advantageous analytical performance. In addition, wearable, clinical, and environmental applications of cellulose-based (bio)sensors are reported, where novel (nano)materials, architectures, signal enhancement strategies, as well as real-time connectivity and portability play a critical role.

Summary: Renewable energy deployment as an alternative to traditional energy sources is the cornerstone of the emission-reduction energy policies that aim to facilitate the transition to a low-carbon economy. This transition poses risks and opportunities for companies with business models that rely directly or indirectly on renewables, which will be reflected in the revaluation of assets and in the reallocation of private and public financial investments from carbon-intensive to low-carbon energies. In a series of selected articles, this book addresses current challenges and opportunities for renewable energies from technological, economic and financial perspectives.

Summary: Composites have increasingly been used in various structural components in the aerospace, marine, automotive, and wind energy sectors. The material characterization of composites is a vital part of the product development and production process. Physical, mechanical, and chemical characterization helps developers to further their understanding of products and materials, thus ensuring quality control. Achieving an in-depth understanding and consequent improvement of the general performance of these materials, however, still requires complex material modeling and simulation tools, which are often multiscale and encompass multiphysics. This Special Issue aims to solicit papers concerning promising, recent developments in composite modeling, simulation, and characterization, in both design and manufacturing areas, including experimental as well as industrial-scale case studies. All submitted manuscripts will undergo a rigorous review process and will only be considered for publication if they meet journal standards. Selected top articles may have their processing charges waived at the recommendation of reviewers and the Guest Editor.

Summary: We are delighted to present this Special Issue to celebrate a remarkable milestone in the journey of Applied Dentistry. With great pleasure, we announce the publication of the journal's 20,000th paper. This remarkable achievement reflects the unwavering commitment and dedication of our esteemed authors, reviewers, and readers who have contributed to the advancement of dental research.Over the years, Applied Dentistry has emerged as a beacon of knowledge, serving as a platform for the dissemination of cutting-edge research and innovative ideas in various domains of dental science. Our journal encompasses a wide range of disciplines, covering everything from dental materials and biomaterials to preventive and therapeutic strategies, from clinical applications to regenerative dentistry.We envision this milestone as a stepping stone toward even greater accomplishments. Through the collaboration and collective efforts of researchers worldwide, we strive to push the boundaries of dental science, explore new frontiers, and improve oral health outcomes for individuals across the globe.In conclusion, we extend our warmest congratulations to all those who have contributed to the publication of the Special Issue celebrating Applied Dentistry's 20,000th paper milestone.

Summary: Personalized medicine is playing an important role in cancer prevention. To date, it is clear that many cancers are molecularly distinct subtypes, and different therapeutic approaches would be required for each. This Special Issue brings together original research and review articles on molecular oncology with attention to the early detection and prevention of cancer. It highlights new findings, methods, and technical advances in molecular cancer research. The main feature of this reprint was to provide an open-source sharing of significant works in the field of molecular oncology that can increase our understanding of cancer development. Topics include:Molecular methods to personalize cancer screening and detection;Molecular target therapies to prevent cancer development and metastases;Identification and new aspects of cellular signaling molecules and pathways for target discovery, drug design and personalized and gender medicine;Drug repurposing for cancer prevention;Molecular modeling studies.

Summary: The book "Building Energy Audits-Diagnosis and Retrofitting" is a collection of twelve papers that focus on the built environment in order to systematically collect and analyze relevant data for the energy use profile of buildings and extended for the sustainability assessment of the built environment. The contributions address historic buildings, baselines for non-residential buildings from energy performance audits, and from in-situ measurements, monitoring, and analysis of data, and verification of energy saving and model calibration for various building types. The works report on how to diagnose existing problems and identify priorities, assess, and quantify the opportunities and measures that improve the overall building performance and the environmental quality and well-being of occupants in non-residential buildings and houses. Several case studies and lessons learned from the field are presented to help the readers identify, quantify, and prioritize effective energy conservation and efficiency measures. Finally, a new urban sustainability audit and rating method of the built environment addresses the complexities of the various issues involved, providing practical tools that can be adapted to match local priorities in order to diagnose and evaluate the current state and future scenarios towards meeting specific sustainable development goals and local priorities.

Summary: Biosensor technologies have received a great amount of interest in recent decades, and this has especially been the case in recent years due to the health alert caused by the COVID-19 pandemic. The sensor platform market has grown in recent decades, and the COVID-19 outbreak has led to an increase in the demand for home diagnostics and point-of-care systems. With the evolution of biosensor technology towards portable platforms with a lower cost on-site analysis and a rapid selective and sensitive response, a larger market has opened up for this technology. The evolution of biosensor systems has the opportunity to change classic analysis towards real-time and in situ detection systems, with platforms such as point-of-care and wearables as well as implantable sensors to decentralize chemical and biological analysis, thus reducing industrial and medical costs. This book is dedicated to all the research related to biosensor technologies. Reviews, perspective articles, and research articles in different biosensing areas such as wearable sensors, point-of-care platforms, and pathogen detection for biomedical applications as well as environmental monitoring will introduce the reader to these relevant topics. This book is aimed at scientists and professionals working in the field of biosensors and also provides essential knowledge for students who want to enter the field.

Summary: Research on human body composition has gained relevance given the recognized health impact of several body components. Many contemporary scientists have contributed to the field of body composition research as it exists today, even though interest in the topic extends back several thousand years. Quantifying human body composition in sports practice plays an important role in monitoring athletes' health status, performances, and training regimens. Such analysis can be performed in different contexts and with different approaches-e.g., in cross-sectional studies that aim to characterize sporting group samples and in longitudinal research finalized to define short-term or long-term changes and implications for physical health and performance. Body composition is also fundamental for a correct interpretation of body mass and weight status to plan specific interventions. This book adds new information on the effect of body composition on physical health and sport performance, current body composition measurement techniques and strategies for improving physical health through sports practice.

Summary: Movement and locomotion have always been key activities for all animals, being related to the most crucial life functions: retrieving food, facing environmental issues and mating. Humans developed complex upper arms movements and bipedal gaits in order to move and locomote. To enhance their performance, they started inventing smart passive mechanical tools. This need arose from intrinsic limitations of their muscle-joint-bone systems and metabolic power availability. Newly invented devices were mainly introduced in order to cope with such constraints. The aim of this Special Issue is to advance knowledge regarding symmetry, biomechanics and energetics of passively assisted human movement and locomotion.

Summary: Biocultural restoration is a process by which the various connections between humanity and nature, as well as between People and Place are revived to restore the health and function of social-ecological systems. This collection explores the subject of biocultural restoration and does so within the context of Hawaiʻi, the most remote archipelago on the planet. The Hawaiian Renaissance, which started in the 1970s, has led to a revival of Hawaiian language, practices, philosophy, spirituality, knowledge systems, and systems of resource management. Many of the leading Indigenous and local scholars of Hawaiʻi who were born into the time of the Hawaiian Renaissance contributed to this collection. More than a third of the authors are of Indigenous Hawaiian ancestry; each paper had at least one Indigenous Hawaiian author, and several papers had a Hawaiian lead author, making this the largest collection to date of scientific publications authored by Indigenous Hawaiians (Kānaka ʻŌiwi). In addition, the majority of authors are women, and two of the papers had 100 percent authorship by women. This collection represents a new emphasis in applied participatory research that involves academics, government agencies, communities and both private and non-profit sectors.

Summary: At present, the increasing demand for novel biotechnological products is supported through the continuous development of biocatalytic applications. As a consequence, the progress of research regarding enzymatic catalysis in aqueous, non-aqueous, organic (polar or non-polar), and/or non-solvent media is decisive. Experimental design methods, which also may comprise in silico studies, the design of specific reactors and conditions, the reactions of significant chemical and/or biochemical processes that are relevant to industrial production, enzyme kinetic methods, the investigation of enzymatic mechanisms and the use of immobilized enzymes and/or microbial cells on various inert matrices, are all useful. A plethora of enzymes of several classes, which may potentially be used as biocatalysts in biotechnological applications, are available. Among these enzymes, the more common are oxidoreductases (laccase, catalase, glucose oxidase, etc.), hydrolases (amylases, lipases, proteases, amidases, cellulases, esterases, etc.), isomerases (epimerases, topoisomerases, mutases, etc.), and others. By means of the aforementioned biocatalysts and the utilization of specific biotechnological methods, important, cost-effective, sustainable, and environmentally friendly processes have been applied for the synthesis and/or the conversion of a huge number of market-required products.

Summary: Dear Colleagues,All types of biomass, and their waste, comprised one the pillars of the preindustrial,pre-fossil fuel, agriculture-based economies of the past. Traditionalpractices of biomass waste management were applied, but not necessarily in asophisticated and efficient way, and included everything from agricultural activitiesto food production, animal feed, natural fiber separation, and processingof forest wood. The modern bioeconomy sector, however, includes new circulareconomy energy and materials streams of added-value products, such asgaseous, liquid and solid biofuels and bioenergy generation routes, and biocharproduction, along with all the previously mentioned traditional products emergingfrom the bioeconomy.This Special Issue includes some of the latest bioenergy and biochar advancementsand their incorporation into a bioeconomy in transition. It focuses onnature, properties, upgrading, and bioenergy generation processes from all typesof biomass waste and biochars originating from biomass waste. The multidisciplinarityof bioenergy and biochar research is evident throughout the SpecialIssue, highlighting the highly variable and tunable processes involved inbiomass handling, pre-processing, converting to biochar, and recovering energy.Dr. Dimitrios KalderisGuest EditorDr. Vasiliki Skoulouco-Guest Editor

Summary: The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology, to the internal workings of a machine-like structure, or to the causal explanation of a particular phenomenon. In this Special Issue, we try to discuss these possible biological mechanisms that underlie the beneficial effects of physical fitness and sports performance, as well their importance and role/influences on physical health.Despite the significant body of knowledge regarding the physiological and physical effects of different training methods (based on dimensions of load), some of the biological causes for those changes are still unknown. Additionally, few studies have focused on the natural biological variability in humans and how specific properties of humans may justify different effects for the same training intervention. Thus, more original research is needed to provide plausible biological mechanisms that may explain the physiological and physical effects of exercise and training in humans.In this Special Issue, we gather the contributions that describe and list the links between physical fitness, sports performance, and human biology.

Summary: This Special Issue, as a continuation of the previous Special Issue, "Bioactive Molecules from Extreme Environments" (https://www.mdpi.com/journal/marinedrugs/special_issues/Extreme_Environments accessed on 4 November 2021), includes 10 research articles and 2 reviews, providing a wide overview of the chemical biodiversity offered by different marine organisms inhabiting extreme environments to be used for biotechnological and pharmaceutical applications. The six articles in this Special Issue are focused on the polar regions, which represent an untapped source of marine natural products and are still largely unexplored compared to more accessible sites. Many of these articles refer to Antarctica, which is the coldest and most inaccessible continent on the Earth, where extreme temperatures, light and ice have selected biological communities with a unique suite of bioactive metabolites. The marine organisms of Arctic and Antarctic environments are a reservoir of natural compounds, exhibiting huge structural diversity and significant bioactivities that could be used in human applications.

Summary: Medicinal plants and natural products have played a central role in therapeutics, being considered the origin of Pharmacy and Pharmacology. Plants are still a source in nature to obtain and isolate molecules with pharmacological applications (drug discovery), but can also be used as herbal medicinal products in traditional or complementary medicine.In addition, the WHO has launched a Traditional Medicine Strategy (2014-2023), including herbal medicines as medicinal therapies, with the aim to ensure the quality, safety, proper use, and effectiveness of traditional medicines, among other objectives.This is a reprint of articles from the Special Issue on "Bioactivity of Medicinal Plants and Extracts" published online in the open access journal Biology. This reprint includes a collection of original research and review articles on new advances in the development and application of bioactive compounds and extracts from plant matrices.

Summary: This book entitled Zeolites is a collection of papers recently published in the journal Crystals, focusing on zeolites as a group of hydrated aluminosilicates with unique physical and chemical properties that can have numerous and important applications. The collection opens with works related to the geological documentation of the newest deposits of natural zeolites. The second part of the book describes a variety of synthesis methods and characterizes the resulting products. Finally, some recent advances in their applications in different fields are presented at the end of the book.

Summary: The book "Advanced Materials for Electrochemical Energy Conversion and Storage Devices" reports new, improved electrocatalytic materials for batteries, capacitors, and fuel cells. These advances are expected to significantly impact the performance of electrochemical energy conversion and storage devices and, consequently, their commercialisation. This book is intended to be a valuable tool for those from industry and academia interested in knowing more about the field.

Summary: Fuel cells are expected to play a relevant role in the transition towards a sustainable-energy-driven world. Although this type of electrochemical system was discovered a long time ago, only in recent years has global energy awareness, together with newly developed materials and available technologies, made such key advances in relation to fuel cell potential and its deployment. It is now unquestionable that fuel cells are recognized, alongside their possibility to work in the reverse mode, as the hub of the new energy deal. Now the questions are, why are they not yet ready to be used, despite the strong economic support given from the society? What prevents them from being entered into the hydrogen energy scenario in which renewable sources will provide energy when it is not readily available? How much are researchers involved in this urgent step towards change? This book gives a clear answer, engaging with some of the open issues that explain the delay of fuel cell deployment and, at the same time, it opens a window that shows how wide and attractive the opportunities offered by this technology are. Papers collected here are not only specialist-oriented but also offer a clear landscape to curious readers and show how challenging the road to the future is.

Summary: Urbanisation and climate change are pushing cities to find novel pathways leading to a sustainable future. The urban context may be viewed as a new experimentation space to accelerate the transition to a circular economy. Urban symbiosis and the circular economy are emerging concepts attracting more and more attention within the urban context. Moreover, new business models are emerging around sharing and peer-to-peer practices, which are challenging existing roles of actors in society. These developments are having an important impact on the flows of resources and the use of the city infrastructure, and each research area has taken a different perspective in the analysis of such impacts. This Special Issue aims to explore what a "circular city" could constitute and how and why cities engage in circularity. This Special Issue includes seven high-quality papers on the theories and practices of circular cities. Actors, concepts, methods, tools, the barriers to and enablers of circular cities are discussed and a solid base and inspiration for the future development of circular cities are provided.

Summary: Wild animals under human care as well as domesticated farm production animals are often exposed to environmental changes (e.g., capture and transportation). Short-term or acute changes in physiological indices (e.g., heart rate, respiration, body temperatures, immune cells, and stress hormonal biomarkers) provide crucial information regarding the responses of animals to novel environments, and they could provide crucial determining factors for the long-term health and welfare of animals. This Special Issue includes experimental research papers that demonstrate the applications of physiological indices and welfare assessment methods (e.g., morphological and morphometric data, behavioural assessments, thermal profiles, and physiological markers) in any wildlife or production animal (e.g., rescued and rehabilitating animals, pets, competition animals, farm animals, and zoo animals), in response to environmental and management related factors. The goal is to provide examples of new research and techniques that can be used to monitor short- and long-term environmental adaptation of animals under human care.

Summary: Currently, the transition from using the combustion engine to electrified vehicles is a matter of time and drives the demand for compact, high-energy-density rechargeable lithium ion batteries as well as for large stationary batteries to buffer solar and wind energy. The future challenges, e.g., the decarbonization of the CO2-intensive transportation sector, will push the need for such batteries even more. The cost of lithium ion batteries has become competitive in the last few years, and lithium ion batteries are expected to dominate the battery market in the next decade. However, despite remarkable progress, there is still a strong need for improvements in the performance of lithium ion batteries. Further improvements are not only expected in the field of electrochemistry but can also be readily achieved by improved manufacturing methods, diagnostic algorithms, lifetime prediction methods, the implementation of artificial intelligence, and digital twins. Therefore, this Special Issue addresses the progress in battery and energy storage development by covering areas that have been less focused on, such as digitalization, advanced cell production, modeling, and prediction aspects in concordance with progress in new materials and pack design solutions.

Summary: The book "Assessment of Renewable Energy Resources with Remote Sensing" focuses on disseminating scientific knowledge and technological developments for the assessment and forecasting of renewable energy resources using remote sensing techniques. The eleven papers inside the book provide an overview of remote sensing applications on hydro, solar, wind and geothermal energy resources and their major goal is to provide state of art knowledge to contribute with the renewable energy resource deployment, especially in regions where energy demand is rapidly expanding. Renewable energy resources have an intrinsic relationship with local environmental features and the regional climate. Even small and fast environment and/or climate changes can cause significant variability in power generation at different time and space scales. Methodologies based on remote sensing are the primary source of information for the development of numerical models that aim to support the planning and operation of an electric system with a substantial contribution of intermittent energy sources. In addition, reliable data and knowledge on renewable energy resource assessment are fundamental to ensure sustainable expansion considering environmental, financial and energetic security.

Summary: Bayesian predictive inference is at the core of the mathematical theory of inductive reasoning. Nowadays, this field has become very attractive especially for its connections with algorithmic probability, machine learning and artificial intelligence. The complexity of both problems and algorithm represents a constant source of research of asymptotic techniques, which are necessary to handle vast datasets. The present book contains the 11 papers accepted and published in the Special Issue "Bayesian Predictive Inference and Related Asymptotics-Festschrift for Eugenio Regazzini's 75th Birthday" of the MDPI Mathematics journal. The topics of the paper focus, among others, on Bayesian nonparametrics, species sampling models, partial exchangeability and optimal stopping. Finally, as the title suggests, the Special Issue aims to celebrate the 75th birthday of Prof. Eugenio Regazzini, who has provided so many important contributions to the field of Bayesian inference.

Summary: This reprint brings together many scientific contributions on current actinide research, both theoretical and experimental. Special attention is given to the theoretical modeling of the atomic spectra of actinides, the experimental study of their atomic and nuclear structure, and new developments in the production and spectroscopy of their elusive and rather exotic radionuclides.

Summary: Atomic layer deposition (ALD) is a thin film deposition process renowned for its ability to produce layers with unrivaled control of thickness and composition, conformability to extreme three-dimensional structures, and versatility in the materials it can produce. These range from multi-component compounds to elemental metals and structures with compositions that can be adjusted over the thickness of the film. It has expanded from a small-scale batch process to large scale production, also including continuous processing - known as spatial ALD. It has matured into an industrial technology essential for many areas of materials science and engineering from microelectronics to corrosion protection. Its attributes make it a key technology in studying new materials and structures over an enormous range of applications. This Special Issue contains six research articles and one review article that illustrate the breadth of these applications from energy storage in batteries or supercapacitors to catalysis via x-ray, UV, and visible optics.

Summary: Natural World Heritage sites, such as the Serengeti, or Natural and Cultural Heritage sites, such as the Historic Centre of Rome, have the common feature of being a treasured resource of global importance. The 1121 properties on the World Heritage (WH) list have permanent recognized value for humankind. Most of those >1000 locations are at some risk from changes in climate. Globally, scholars and managers seek to understand current and future climatic stresses, mitigation and adaptation opportunities. There is a strong need for the "So What?" in World Heritage studies. The invited papers in this volume address natural, cultural and mixed WH sites, and each offers a fresh perspective on assessing the degree of risk from changing climate and guidance on acting to mitigate and adapt to climate changes to provide new awareness and tools to improve their state of conservation for the future.

Summary: Satisfying consumer needs through the production of healthy and nutritious agricultural products is a substantial challenge facing modern agriculture. However, agricultural production should be carried out with care for plant health, biological safety of products, and environmental safety while minimizing the risks to human health. Therefore, the implementation of agricultural practices while respecting these principles is very important for improving the quantity and quality of crops. Additionally, ecosystems have been altered as a result of human activities and climate change, resulting in the reduction of biodiversity and creation of new niches where pests can thrive. This is of particular importance in 2020, as the United Nations General Assembly declared this year as the International Year of Plant Health (IYPH), with "protecting plants, protecting life" as a leading subject.This Special Issue promotes the subject of plant health and emphasize the importance of preventing the spread of pests, including weeds, which cause substantial economic losses. Research articles cover topics related to the biology and harmfulness of weeds, particularly in connection with crop health, segetal weed communities and their biodiversity, and integrated methods of weed control. For this Special Issue, we welcome all types of articles, including original research, opinions, and reviews.

Summary: This special issue entitled "Water Quality Assessments for Urban Water Environment," strives to highlights the status quo of water environment, opportunities and challenges for their sustainable management in lieu of rapid global changes (land us eland cover changes, climate change, population growth, change in socio-economic dimension, urbanization etc.), in the urban space particularly in developing nations around the world. It also highlights the effect of COVID19 pandemic on water resources and way forward to minimize the risk of spreading health risk associated with wastewater management. Considering the complex nature of the urban water security, it highlights the importance of emerging approaches like socio-hydrology, landscape ecology, regional-circular-ecological sphere etc., which presents a perfect combination of hard (infrastructure) and soft (numerical simulations, spatial technologies, participatory approaches, indigenous knowledge) measures, as the potential solutions to manage this precious water resource in coming future. Finally, what is the way forward to enhance science-policy interface in a better way to achieve global goals e.g., SDGs at local level in a timely manner. It provides valuable information about sustainable water resource management at the urban landscape, which is very much useful for policy-makers, decision-makers, local communities, and other relevant stakeholders.

Summary: Wildfire risk can be perceived as the combination of wildfire hazards (often described by likelihood and intensity) with the susceptibility of people, property, or other valued resources to that hazard. Reflecting the seriousness of wildfire risk to communities around the world, substantial resources are devoted to assessing wildfire hazards and risks. Wildfire hazard and risk assessments are conducted at a wide range of scales, from localized to nationwide, and are often intended to communicate and support decision making about risks, including the prioritization of scarce resources. Improvements in the underlying science of wildfire hazard and risk assessment and in the development, communication, and application of these assessments support effective decisions made on all aspects of societal adaptations to wildfire, including decisions about the prevention, mitigation, and suppression of wildfire risks. To support such efforts, this Special Issue of the journal Fire compiles articles on the understanding, modeling, and addressing of wildfire risks to homes, water resources, firefighters, and landscapes.

Summary: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and still represents one of the global health threats to mankind. The World Health Organization estimated more than 10 million new cases and reported more than 1.5 million deaths in 2019, thus ranking TB among the main causes of death due to a single pathogen. Standard anti-TB therapy includes four first-line antibiotics that should be administered for at least six months. However, in the case of multi- and extensively drug-resistant TB, second-line medications must be used and these frequently cause severe side effects resulting in poor compliance. Developing new anti-TB drug candidates is therefore of outmost importance. In this Special Issue dedicated to Tuberculosis Drug Discovery and Development, we present the main and latest achievements in the fields of drug and target discovery, host-directed therapy, anti-virulence drugs, and describe the development of two advanced compounds: macozinone and delpazolid. In addition, this Special Issue provides an historical perspective focused on Carlo Forlanini, the inventor of pneumothorax for TB treatment, and includes an overview of the state-of-the-art technologies which are being exploited nowadays in TB drug development. Finally, a summary of TB vaccines that are either approved or undergoing clinical trials concludes the Special Issue.

Summary: The available range of ornamental plants (cut flowers, potted plants, perennials, bulbous, woody ornamental plants) is constantly being supplemented with new species and cultivars; thus, new methods for their production are required. The sustainable development of the floriculture industry requires modern and environmentally friendly solutions that can maximize the plant's potential. Therefore, it is necessary to adapt flower production methods to actual conditions and take into account the energy transformation and biological, technical, and organizational advances. This Special Issue is a collection of seven well-written research works covering the current state-of-the-art of ornamental crop production. The main body of the Special Issue gives an interesting coverage of new strategies that can be utilized for plant reproduction, regulating their growth and flowering, adapting production technologies to fit the concept of sustainable development, and optimizing supply chain management. This Special Issue will provide a good reference source for growers, research scientists, and advanced undergraduate students.

Summary: This reprint contains original research and review articles describing recent advances in our understanding of the transcriptional regulation of cardiac development and disease mechanisms. All articles were originally published in the International Journal of Molecular Sciences (IJMS).

Summary: There are several types of training methods aiming to develop sports performance and improve health indicators. Fundamentally, training methods are the result of manipulating different training variables, and the possibility of combining these variables is vast. Therefore, the search to study the effect of these constraints on sports and health, considering specific contexts and taking into account the magnitude of inter-individual responses, will afford a better understanding of the training interventions.At the same time, over the years, numerous innovations and technological advances have been introduced to assist the development of athletes' performance and monitor individual lifestyles. These advances have changed how training may be conducted, controlled, and evaluated. For example, in sport settings, using technology to collect many and continuous data of athletes' activity in their natural environments appears as an innovative and promising step. In health, an enormous diversity of training methods supporting healthy lifestyles and innovative approaches is arising, especially from higher-quality information gathered through technological development.Papers addressing these topics are included in this book, especially those combining a high academic standard with a practical focus on providing knowledge on how training methods improve sports performance and health across people's lifespans. New evidence urges us to track the progress and effects of training methods.

Summary: This Special Issue includes 20 contributions from across the world with very interesting and current research topics, such as insulation solutions and CO2 emissions; thermal transmittance of LSF walls; statistics for China's building energy consumption; natural ventilation; thermal behavior of an earthbag building; thermal performance and comfort in a vernacular building; overheating risk under future extreme weather conditions; analytical methods to estimate the thermal transmittance of LSF walls; model simplification on energy and comfort simulation analysis; Trombe wall thermal behavior and energy efficiency of an LSF compartment; new metering hot box for in situ hygrothermal measurement; mechanical and thermal performance of compressed earth blocks; life-cycle assessment of a new house; energy analyses of Serbian buildings with horizontal overhangs; thermal properties of mortar blocks by using recycled glass; prediction of cooling energy consumption building using machine learning techniques; occupants' behavior, climate change, heating, and cooling energy needs of buildings; a new method for establishing a hygrothermally controlled test room; nonintrusive measurements to incorporate the air renovations in dynamic models; and retrofit of existing buildings with aerogel panels.

Summary: The THz region of the electromagnetic spectrum is a frontier research area involving application of many disciplines, from outdoor to indoor communications, security, drug detection, biometrics, food quality control, agriculture, medicine, semiconductors, and air pollution. THz research is highly demanding in term of sources with high power and time resolution, detectors, and new spectrometer systems. Many open questions still exist regarding working at THz frequencies; many materials exhibit unusual or exotic properties in the THz domain, and researchers need new methodologies to exploit these opportunities. This book contains original papers dealing with emerging applications, new devices, sources and detectors, and materials with advanced properties for applications in biomedicine, cultural heritage, technology, and space.

Summary: This book gathers a collection of papers summarizing some of the latest developments in the thermomechanical processing of steels. The replacement of conventional rolling plus post-rolling heat treatments by integrated controlled forming and cooling strategies implies important reductions in energy consumption, increases in productivity and more compact facilities in the steel industry. The metallurgical challenges that this integration implies, though, are relevant and impressive developments that have been achieved over the last 40 years. The frequency of the development of new steel grades and processing technologies devoted to thermomechanically processed products is increasing, and their implementation is being expended to higher value added products and applications. In addition to the metallurgical peculiarities and relationships between chemical composition, process and final properties, the relevance impact of advanced characterization techniques and innovative modelling strategies provides new tools to achieve the further deployment of the TMCP technologies. The contents of the book cover low carbon microalloyed grades, ferritic stainless steels and Fe-Al-Cr alloys, medium-Mn steels, and medium carbon grades. Authors of the chapters of this "Thermomechanical Processing of Steels" book represent some of the most relevant research groups from both the steel industry and academia.

Summary: This theme issue is to celebrate Professor Robert Verpoorte's 75th birthday. Prof. Verpoorte has been working in Leiden University over 40 years. There is no need to dwell upon the contributions of Dr. Verpoorte to plant-derived natural products research during his whole life. Dr. Verpoorte was a highly productive scientist throughout his academic career, with over 800 scientific publications in the form of research papers, books, and book chapters. His research interests are very diverse, cover- ing numerous topics related to plant-based natural products such as plant cell biotech- nology, biosynthesis, metabolomics, genetic engineering, and green technology, as well as the isolation of new biologically active compounds. He has left indelible footprints in all these fields, and he is widely recognised as a pioneer in the work of the biosynthesis of indole alkaloids, NMR-based metabolomics, and green technology in natural products production. As close friends and colleagues who have been in nearly daily contact with him over the last 20 years viewing all of these remarkable scientific contributions, we felt compelled to recognize this by the publication of a Special Issue of this journal dedicated to him.Thus, this Special Issue has now finally been released with the help of many of his colleagues and former students as a token of our gratitude to his impressive work.The Special Issue covers five main natural products topics: (1) chemical profiling and metabolomics, (2) separation/isolation and identification of plant specialized metabolites, (3) pharmacognosy of natural products to identify bioactive molecules from natural prod- ucts, (4) novel formulation of natural products, and (5) overview of natural products as a source of bioactive molecules.

Summary: Nine manuscripts were published in this Special Issue on "Theoretical and Computational Research in Various Scheduling Models, 2021" of the MDPI Mathematics journal, covering a wide range of topics connected to the theory and applications of various scheduling models and their extensions/generalizations. These topics include a road network maintenance project, cost reduction of the subcontracted resources, a variant of the relocation problem, a network of activities with generally distributed durations through a Markov chain, idea on how to improve the return loading rate problem by integrating the sub-tour reversal approach with the method of the theory of constraints, an extended solution method for optimizing the bi-objective no-idle permutation flowshop scheduling problem, the burn-in (B/I) procedure, the Pareto-scheduling problem with two competing agents, and three preemptive Pareto-scheduling problems with two competing agents, among others. We hope that the book will be of interest to those working in the area of various scheduling problems and provide a bridge to facilitate the interaction between researchers and practitioners in scheduling questions. Although discrete mathematics is a common method to solve scheduling problems, the further development of this method is limited due to the lack of general principles, which poses a major challenge in this research field.

Summary: The cultivation and harvesting of sugar beets (roots and haulm) is one of the most labour and energy consuming work processes in the agricultural industry. The improvement of the qualitative indicators of the sugar beet harvesting process as the final operation in the work flow of its production represents a multi-faceted research-and-engineering problem, which is to be solved basing on the search for new implement design concepts and overall beet harvester design layouts, the thorough theoretical substantiation of their design and process parameters, the experimental verification of the completed theoretical research with the ultimate objective of the analysis and synthesis of their rational parameters. Theoretical research must play a fundamental role in the mechanical and technological substantiation of the root lifting process. It must be used as the basis for developing rational kinematic and dynamic operation conditions in order to achieve the required quality of the performed work process as well as the streamlined energy consumption. The book can be considered as one of the first solid analytical studies of the process of vibrational digging of sugar beet roots. It offers the analysis of up-to-date engineering solutions of vibrational digging tools and experimental investigations of the first vibrational lifters, the equation of oscillating motions of digging shares.