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215 results on '"Renaudin, H."'

18. Cloning, stability and modification of Mycoplasma hominis genome in yeast

Author

Rideau, Fabien, Le Roy, C., Renaudin, H., Lartigue, Carole, Bebear, Cécile, ProdInra, Migration, Université de Bordeaux (UB), Biologie du fruit et pathologie (BFP), Université Bordeaux Segalen - Bordeaux 2-Institut National de la Recherche Agronomique (INRA)-Université Sciences et Technologies - Bordeaux 1, and International Organization for Mycoplasmology (IOM).

Subjects
Mycoplasma hominis, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Vaa, yeast, TAR cloning, CRISPR/Cas9, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, ComputingMilieux_MISCELLANEOUS, genome stability
Abstract

International audience

Published
2018

23. Development of a molecular typing method of Mycoplasma pneumoniae based on single nucleotide polymorphisms

Author

Touati, A., Blouin, Y., Sirand-Pugnet, Pascal, Renaudin, H., Vergnaud, G, Bebear, Cecile, Pereyre, Sabine, ProdInra, Migration, Université Sciences et Technologies - Bordeaux 1, Université Paris-Sud - Paris 11 (UP11), Biologie du fruit et pathologie (BFP), and Université Sciences et Technologies - Bordeaux 1-Université Bordeaux Segalen - Bordeaux 2-Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, [SDV.BA.MVSA] Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2014

26. In Vitro Activity of Trovafloxacin Compared to Those of Five Antimicrobials against Mycoplasmas Including Mycoplasma hominis and Ureaplasma urealyticum Fluoroquinolone-Resistant Isolates That Have Been Genetically Characterized

Author

Bebear, C. M., Renaudin, H., Charron, A., Gruson, D., Lefrancois, M., and Bebear, C.

Subjects
Ofloxacin, Drug Resistance, Microbial, Microbial Sensitivity Tests, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, urologic and male genital diseases, female genital diseases and pregnancy complications, Anti-Bacterial Agents, Erythromycin, Mycoplasma hominis, Susceptibility, Ciprofloxacin, Doxycycline, bacteria, Humans, Naphthyridines, Ureaplasma urealyticum, Fluoroquinolones
Abstract

The in vitro activity of trovafloxacin against 125 strains of Mycoplasma species and Ureaplasma urealyticum, including fluoroquinolone-susceptible and fluoroquinolone-resistant species, was compared to those of other fluoroquinolones, doxycycline, and erythromycin. The MIC at which 90% of isolates are inhibited for all fluoroquinolone-susceptible strains was 0.25 microg/ml. Whatever the associated mutations, trovafloxacin exhibited greater activity than the other fluoroquinolones tested against fluoroquinolone-resistant Mycoplasma hominis and U. urealyticum isolates.

Published
2000

49. Potential Role of Mycoplasma hominis in Interleukin (IL)-17-Producing CD4+ T-Cell Generation Via Induction of IL-23 Secretion by Human Dendritic Cells.

Author

Truchetet ME, Beven L, Renaudin H, Douchet I, Férandon C, Charron A, Blanco P, Schaeverbeke T, Contin-Bordes C, and Bébéar C

Abstract

Background. Mycoplasma hominis, a human urogenital pathogen, is involved in genital and extragenital infections and arthritis, particularly in immunocompromised patients. The interleukin (IL) 23/T helper (Th) 17 axis is associated with inflammatory and autoimmune diseases. The aim of this study was to assess the IL-23 response to M. hominis in human dendritic cells (DCs) and the CD4(+) T-cell differentiation in response to M. hominis-infected DCs. Methods. Human monocyte-derived DCs were cultured with phosphate-buffered saline, lipopolysaccharide, or M. hominis PG21. Cocultures with heterologous T cells were performed. Extracts from M. hominis were separated and incubated with DCs. Isolates from different clinical syndromes were tested. Results. M. hominis induced the maturation of human DCs with predominant IL-23 secretion in a Toll-like receptor 2-dependent manner. The in vitro immunomodulatory capacity of M. hominis was contained in a lipoprotein-enriched fraction from the mycoplasma. M. hominis-activated DCs induced IL-17-producing CD4(+) T cells. Interestingly, clinical isolates differed in their ability to promote IL-23 secretion by DCs. Conclusions. Taken together, our findings demonstrate a major role for the IL-23/Th17 axis in the defense against M. hominis and indicate a potential role for these bacteria in inflammatory and autoimmune diseases. [ABSTRACT FROM AUTHOR]

Published
2011

50. In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas.

Author

Bébéar, CM, Renaudin, H, Schaeverbeke, T, LeBlanc, F, Bébéar, C, and Bébéar, C M

Abstract

The in-vitro activity of grepafloxacin, a new oral fluoroquinolone antibiotic, was compared with those of three other fluoroquinolones and two unrelated antimicrobials, doxycycline and erythromycin, against various Mycoplasma spp. For 65 mycoplasma and 42 ureaplasma strains, grepafloxacin (MIC range 0.03-2 mg/L) was some two to 16 times more active than ofloxacin and ciprofloxacin, showing similar activity to that of sparfloxacin. MBCs of grepafloxacin increased two- to 16-fold when compared with MICs and were comparable to those of sparfloxacin, and lower than those of ofloxacin and ciprofloxacin. [ABSTRACT FROM AUTHOR]

Published
1999
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