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Of 210 pathologically confirmed palpable breast masses examined by continuous ultrasound B-scanning using a 2.5- or 7-MHz transducer and mammography, fluid filled cysts more than 1 cm in diameter were diagnosed accurately in 75 cases. Of the 103 solid masses studied by echography, 31 were circumscribed (29 benign fibroadenomas and 2 circumscribed medullary carcinomas) and 72 were not. Infiltrating carcinoma represented the majority of the latter type, although 2 cases of chronic inflammation had the same echographic appearance. Thirty palpable breast masses less than 2 cm in diameter were not delineated with the 2.5-MHz transducer, and biopsy showed benign disease. The combination of mammography and continuous ultrasound B-scanning of palpable breast masses improved the diagnostic accuracy obtained with mammography alone and aided in the differentiation of nondiagnostic mammograms.

In the three and a half year period beginning October, 1949, about 500 patients were treated by rotational and multiportal methods with supervoltage roentgen rays produced at two million volts. Most of these patients had advanced malignant disease. It has become evident that the patient treated with 2 million volt radiation is usually able to accept tissue doses in the 6,000 r to 8,000 r range delivered in 35 treatment days or 7 elapsed weeks and that larger fields that include adjacent regions of lymphatic spread can be included in such treatment. Radiation sickness is markedly less than would be obtained with smaller doses of conventional radiation, and, the skin reaction is often a threshold or moderate erythema when the skin is included in the region of treatment. Moist skin reactions may be encountered in special situations such as irradiation of the folds of the skin or when the x-ray