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Your search keyword '"Reinhardt, Renate"' showing total 22 results
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22 results on '"Reinhardt, Renate"'

7. PET-Computertomographie (PET-CT) nach endovaskulärer Aortenchirurgie: Hilft uns die High-tech Diagnostik beim Graftinfekt wirklich immer weiter?

Author

Juntermanns, Benjamin, Cyrek, Anna, Bernheim, Johannes Konstantin, Reinhardt, Renate, Burzec, Wieslaw, Paul, Andreas, and Hoffmann, Johannes Nikolaus

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Die Behandlung von infizierten endovaskulär eingebrachten Aortengrafts ist mit einer hohen Morbidität und Mortalität vergesellschaftet. Neben klinischen Parametern und Laborparametern wird der PET-CT eine zunehmende Rolle in der Standardiagnostik bei Protheseninfekten zugewiesen.[zum vollständigen Text gelangen Sie über die oben angegebene URL], 133. Kongress der Deutschen Gesellschaft für Chirurgie

Published
2016
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8. Analysis of risk factors for development of Early Allograft Dysfunction (EAD) after liver transplantation: A Single Center Study of 678 patients

Author

Hoyer, Dieter Paul, Mathé, Zoltan, Treckmann, Jürgen-Walter, Reinhardt, Renate, Gallinat, Anja, Minor, Thomas, Saner, Fuat, Sotiropoulos, Georgios C., Gerken, Guido, and Paul, Andreas

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Introduction: Introduction: Organ shortage and the constantly aging donor population lead nowadays to an increasing acceptance of expanded criteria donor (ECD) livers. These livers are more frequently associated with early allograft dysfunction (EAD) and impaired patient and graft survival. The aim[for full text, please go to the a.m. URL], 130. Kongress der Deutschen Gesellschaft für Chirurgie

Published
2013
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12. Erfolgreiche Nierentransplantation bei kongenitaler Vena cava und rechtsseitiger Arteria ilaca Hypoplasie

Author

Reinhardt, Renate, Treckmann, Jürgen, Radünz, Sonja, Arns, Wolfgang, Witzke, Oliver, and Paul, Andreas

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Wir berichten über eine erfolgreiche orthotope Nierentransplantation bei einer Patientin mit kongenitaler Hypoplasie der Vena cava inferior sowie der rechtsseitigen Iliakalgefäße. Die Patientin entwickelte auf Grund einer chronischen Glomerulonephritis eine dialysepflichtige[for full text, please go to the a.m. URL], 127. Kongress der Deutschen Gesellschaft für Chirurgie

Published
2010

17. Real-Time Magnetic Resonance Imaging–Guided Transarterial Aortic Valve Implantation

Author

Kahlert, Philipp, primary, Parohl, Nina, additional, Albert, Juliane, additional, Schäfer, Lena, additional, Reinhardt, Renate, additional, Kaiser, Gernot M., additional, McDougall, Ian, additional, Decker, Brad, additional, Plicht, Björn, additional, Erbel, Raimund, additional, Eggebrecht, Holger, additional, Ladd, Mark E., additional, and Quick, Harald H., additional

Published
2012
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18. Ten-year survival of esophageal cancer after an en-bloc esophagectomy

Author

Oezcelik, Arzu, primary, Kaiser, Gernot M., additional, Niebel, Wolfgang, additional, Sleyman, Christopher, additional, Treckmann, Juergen W., additional, Sotiropoulos, Georgios C., additional, Reinhardt, Renate, additional, Trarbach, Tanja, additional, Malamutmann, Eugen, additional, and Paul, Andreas, additional

Published
2011
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20. Invasive Surgery Impairs the Regulatory Function of Human CD56bright Natural Killer Cells in Response to Staphylococcus aureus. Suppression of Interferon-γ Synthesis.

Author

Reinhardt, Renate, Pohlmann, Stephanie, Kleinertz, Holger, Hepner-Schefczyk, Monika, Paul, Andreas, and Flohé, Stefanie B.

Subjects
*CD antigens, *STAPHYLOCOCCUS aureus, *KILLER cells, *CHEMICAL synthesis, *INTERFERONS, *SURGICAL complications
Abstract

Major surgery increases the risk for infectious complications due to the development of immunosuppression. CD56bright NK cells play a key role in the defense against bacterial infections through the release of Interferon (IFN) γ upon stimulation with monocyte-derived Interleukin (IL) 12. We investigated whether invasive visceral surgery interferes with the IFN-γ synthesis of human NK cells in response to Staphylococcus aureus. In a prospective pilot study, peripheral blood mononuclear cells (PBMC) were isolated from 53 patients before and 1 to 7 d after elective visceral surgery. The release of IL-12 and IFN-γ from PBMC upon exposure to S. aureus in vitro was quantified. The expression of the IL-12 receptor β1 chain on the surface, the phosphorylation of signal transducer and activator of transcription (STAT) 4, and the synthesis of IFN-γ on/in individual CD56bright NK cells were investigated using flow cytometry. The modulatory effect of IL-12 on the S. aureus-induced IFN-γ production in CD56bright NK cells was analyzed. The IFN-γ secretion from purified CD56bright NK cells was quantified after stimulation with IL-12 and IL-18. After surgery, CD56bright NK cells among total PBMC were impaired in the release of IFN-γ for at least 5 d. Likewise, the IL-12-induced release of IFN-γ from purified CD56bright NK cells was abolished. Upon stimulation with S. aureus, PBMC secreted less IL-12 but supplementation with recombinant IL-12 did not restore the capacity of CD56bright NK cells to produce IFN-γ. CD56bright NK cells displayed reduced levels of the IL-12Rβ1 chain whereas the phosphorylation of STAT4, the key transcription factor for the Ifng gene was not diminished. In summary, after invasive visceral surgery, CD56bright NK cells are impaired in S. aureus-induced IFN-γ production and might contribute to the enhanced susceptibility to opportunistic infections. [ABSTRACT FROM AUTHOR]

Published
2015
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