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2. Cardiovascular outcomes in patients with homozygous familial hypercholesterolaemia on lipoprotein apheresis initiated during childhood: long-term follow-up of an international cohort from two registries

Author

Reijman, M Doortje, Tromp, Tycho R, Hutten, Barbara A, Hovingh, G Kees, Blom, Dirk J, Catapano, Alberico L, Cuchel, Marina, Dann, Eldad J, Gallo, Antonio, Hudgins, Lisa C, Raal, Frederick J, Ray, Kausik K, Sadiq, Fouzia, Soran, Handrean, Groothoff, Jaap W, Wiegman, Albert, and Kusters, D Meeike

Published
2024
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3. Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolaemia: An expert consensus statement from ERKNet and ESPN

Author

Reijman, M. Doortje, Kusters, D. Meeike, Groothoff, Jaap W., Arbeiter, Klaus, Dann, Eldad J., de Boer, Lotte M., de Ferranti, Sarah D., Gallo, Antonio, Greber-Platzer, Susanne, Hartz, Jacob, Hudgins, Lisa C., Ibarretxe, Daiana, Kayikcioglu, Meral, Klingel, Reinhard, Kolovou, Genovefa D., Oh, Jun, Planken, R. Nils, Stefanutti, Claudia, Taylan, Christina, Wiegman, Albert, and Schmitt, Claus Peter

Published
2024
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7. Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study

Author

Tromp, Tycho R., Hartgers, Merel L., Hovingh, G. Kees, Vallejo-Vaz, Antonio J., Ray, Kausik K., Soran, Handrean, Freiberger, Tomas, Bertolini, Stefano A., Harada-Shiba, Mariko, Pang, Jing, Watts, Gerald F., Greber-Platzer, Susanne, Mäser, Martin, Stulnig, Thomas M., Ebenbichler, Christoph F., Bin Thani, Khalid, Cassiman, David, Descamps, Olivier S., Rymen, Daisy, Witters, Peter, Santos, Raul D., Brunham, Liam R., Francis, Gordon A., Genest, Jacques, Hegele, Robert A., Kennedy, Brooke A., Ruel, Isabelle, Sherman, Mark H., Jiang, Long, Wang, Luya, Reiner, Željko, Blaha, Vladimir, Ceska, Richard, Dvorakova, Jana, Dlouhy, Lubomir, Horak, Pavel, Soska, Vladimir, Tichy, Lukas, Urbanek, Robin, Vaverkova, Helena, Vrablik, Michal, Zemek, Stanislav, Zlatohlavek, Lukas, Emil, Sameh, Naguib, Tarek, Reda, Ashraf, Béliard, Sophie, Bruckert, Eric, Gallo, Antonio, Elisaf, Moses S., Kolovou, Genovefa, Cohen, Hofit, Durst, Ronen, Dann, Eldad J., Elis, Avishay, Hussein, Osama, Leitersdorf, Eran, Schurr, Daniel, Setia, Nitika, Verma, Ishwar C., Alareedh, Mohammed D., Al-Khnifsawi, Mutaz, Abdalsahib Al-Zamili, Ali F., Rhadi, Sabah H., Shaghee, Foaad K., Arca, Marcello, Averna, Maurizio, Bartuli, Andrea, Bucci, Marco, Buonuomo, Paola S., Calabrò, Paolo, Calandra, Sebastiano, Casula, Manuela, Catapano, Alberico L., Cefalù, Angelo B., Cicero, Arrigo F.G., D'Addato, Sergio, D'Erasmo, Laura, Di Costanzo, Alessia, Fasano, Tommaso, Gazzotti, Marta, Giammanco, Antonina, Iannuzzo, Gabriella, Ibba, Anastasia, Negri, Emanuele A., Pasta, Andrea, Pavanello, Chiara, Pisciotta, Livia, Rabacchi, Claudio, Ripoli, Carlo, Sampietro, Tiziana, Sbrana, Francesco, Sileo, Fulvio, Suppressa, Patrizia, Tarugi, Patrizia, Trenti, Chiara, Zenti, Maria G., Hori, Mika, Ayesh, Mahmoud H., Azar, Sami T., Bitar, Fadi F., Fahed, Akl C., Moubarak, Elie M., Nemer, Georges, Nawawi, Hapizah M., Madriz, Ramón, Mehta, Roopa, Cupido, Arjen J., Defesche, Joep C., Reijman, M. Doortje, Roeters-van Lennep, Jeanine E., Stroes, Erik S.G., Wiegman, Albert, Zuurbier, Linda, Al-Waili, Khalid, Sadiq, Fouzia, Chlebus, Krzysztof, Bourbon, Mafalda, Gaspar, Isabel M., Lalic, Katarina S., Ezhov, Marat V., Susekov, Andrey V., Groselj, Urh, Charng, Min-Ji, Khovidhunkit, Weerapan, Aktan, Melih, Altunkeser, Bulent B., Demircioglu, Sinan, Kose, Melis, Gokce, Cumali, Ilhan, Osman, Kayikcioglu, Meral, Kaynar, Leyla G., Kuku, Irfan, Kurtoglu, Erdal, Okutan, Harika, Ozcebe, Osman I., Pekkolay, Zafer, Sag, Saim, Salcioglu, Osman Z., Temizhan, Ahmet, Yenercag, Mustafa, Yilmaz, Mehmet, Yilmaz Yasar, Hamiyet, Mitchenko, Olena, Lyons, Alexander R.M., Stevens, Christophe A.T., Brothers, Julie A., Hudgins, Lisa C., Nguyen, Christina, Alieva, Rano, Shek, Aleksandr, Do, Doan-Loi, Kim, Ngoc-Thanh, Le, Hong-An, Le, Thanh-Tung, Nguyen, Mai-Ngoc T., Truong, Thanh-Huong, Blom, Dirk J., Raal, Frederick J., Cuchel, Marina, Tromp, Tycho R, Hartgers, Merel L, Hovingh, G Kees, Vallejo-Vaz, Antonio J, Ray, Kausik K, Bertolini, Stefano, Blom, Dirk J, and Raal, Frederick J

Published
2022
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10. Decreased LDL cholesterol exposure following ANGPTL3 inhibition reduces coronary plaque development in Homozygous Familial Hypercholesterolemia

Author

Schonck, Willemijn AM., primary, Reijman, M. Doortje, additional, Wiegman, Albert., additional, Ibrahim, Shirin, additional, Corpeleijn, Willemijn E., additional, Planken, R. Nils, additional, Hovingh, G. Kees, additional, Stroes, Erik S.G., additional, Nurmohamed, Nick S., additional, and Reeskamp, Laurens F., additional

Published
2024
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14. Should we always perform scaphoid nonunion surgery in patients with minor preoperative symptoms?

Author

Cohen, A, Reijman, M, Selles, RW, Hovius, SER, Colaris, JW, Cohen, A, Reijman, M, Selles, RW, Hovius, SER, and Colaris, JW

Abstract

The objective of this study was to assess the downsides of surgical treatment of scaphoid fracture nonunion in patients with minor preoperative symptoms. Patients were classified with minor symptoms based on the Patient-Rated Hand/Wrist Evaluation questionnaire. Of the 35 included patients, most patients encountered problems with patient-specific activities; 9% reported worse postoperative functional outcomes, 34% were not satisfied with the treatment and 9% were reoperated. The risk of a worse functional outcome after surgery with the need for further operations and the chance of developing wrist osteoarthritis, along with the possibility of poor patient satisfaction and ongoing daily functional impairment, should be considered during preoperative counselling.

Published
2024

16. Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolemia: an expert consensus statement from ERKNet and ESPN

Author

Reijman, M. Doortje, primary, Kusters, D. Meeike, additional, Groothoff, Jaap W., additional, Arbeiter, Klaus, additional, Dann, Eldad J., additional, de boer, Lotte M., additional, de Ferranti, Sarah D., additional, Gallo, Antonio, additional, Greber-Platzer, Susanne, additional, Hartz, Jacob, additional, Hudgins, Lisa Cooper, additional, Ibarretxe, Daiana, additional, Kayikcioglu, Meral, additional, Klingel, Reinhard, additional, Kolovou, Genovefa, additional, Oh, Jun, additional, Planken, R. Nils, additional, Stefanutti, Claudia, additional, Taylan, Christina, additional, Wiegman, Albert, additional, and Schmitt, Claus Peter, additional

Published
2023
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17. HOFH is a life limiting condition: The life journey of deceased HOFH patients in the HICC registry

Author

Mulder, Janneke W.C.M., Reijman, M. Doortje, Kusters, D. Meeike, Boersma, Eric, Blom, Dirk, Cuchel, Marina, Dann, Eldad J., Freiberger, Tomas, Groselj, Urh, Harada-Shiba, Mariko, Hovingh, G., Ibarretxe, Daiana, Kim, Thanh, Klingel, Reinhard, Raal, Frederick J., Reeskamp, Laurens, Sadiq, Fouzia, Schonck, Willemijn, Truong, Huong, Tromp, Tycho R., Wiegman, Albert, and Van Lennep, Jeanine Roeters

Published
2024
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24. The impact of the COVID-19 pandemic on different aspects of the delivery of physical therapy after total hip or knee surgery

Author

Groot, L., Vlieland, T.P.M.V., Peter, W.F.H., Yildiz, U., Reijman, M., Gademan, M.G.J., and PaTIO Study Grp

Subjects
Nursing (miscellaneous), COVID-19, Physical Therapy, Sports Therapy and Rehabilitation, rehabilitation, Physical Therapists, Rheumatology, Humans, Orthopedic Procedures, Orthopedics and Sports Medicine, Chiropractics, Pandemics, Physical Therapy Modalities, physiotherapy, orthopaedics
Published
2022
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28. Effect of tranexamic acid on intraoperative blood loss in pediatric osteotomies around the hip:Study protocol for a double-blind randomized placebo-controlled trial

Author

van Kouswijk, HW, Tolk, JJ, van Bommel, CPE, Reijman, M, Kempink, DRJ, de Witte, PB, van Kouswijk, HW, Tolk, JJ, van Bommel, CPE, Reijman, M, Kempink, DRJ, and de Witte, PB

Abstract

Background: Proximal femoral and/or pelvic osteotomies (PFPOs) can be indicated for a multitude of hip pathologies in (often asymptomatic) children, to prevent future hip problems. These procedures can result in significant blood loss. Tranexamic acid (TXA) is an antifibrinolytic agent routinely administered in adult trauma and joint reconstruction surgery to reduce blood loss. TXA is also registered for use in children and reported safe and beneficial for pediatric trauma, cardiac, and spinal surgery. However, for pediatric orthopedics, particularly for PFPOs, the available evidence is limited. Therefore, the current trial will investigate the potential reducing effect of preoperative TXA on intraoperative blood loss in pediatric PFPOs. Methods: In this single-center, double-blind, randomized placebo-controlled trial, we aim to include 180 participants aged from 1 to 18 years undergoing PFPOs for any indication at our institution. Participants will be randomized to receive either TXA or placebo (saline) during anesthetic induction. The primary outcome is intraoperative estimated blood loss (mL/kg), which is determined gravimetrically. Secondary outcomes include the percentage of patients with excessive blood loss (>20 mL/kg), procedure time and hospital stay, and postoperative hemoglobin level changes. Discussion: This will be the first prospective study investigating the effect of preoperative TXA on intraoperative blood loss in pediatric PFPOs. Its results will help to determine whether it would be advisable to adopt preoperative TXA as a standard medication to minimize blood loss and prevent complications in this vulnerable population. Trial registration: EudraCT: 2022-002384-30. Prospectively registered on September 26, 2022.

Published
2023

29. OARSI year in review 2023:Rehabilitation and outcomes

Author

Macri, E. M., Selles, R. W., Stefanik, J. J., Reijman, M., Macri, E. M., Selles, R. W., Stefanik, J. J., and Reijman, M.

Abstract

Objective: We systematically reviewed the literature to identify comparative studies of core treatments (exercise, education, or weight management), adjunct treatments (e.g. electrotherapeutical modalities, bracing), or multimodal treatments (core plus other treatments), for treating osteoarthritis (OA) complaints, published between 1 March 2022 and 1 March 2023. Design: We searched three electronic databases for peer-reviewed comparative studies evaluating core treatments, adjunct treatments, or multimodal treatments for OA affecting any joint, in comparison to other OA treatments. Two authors independently screened records. Methodological quality was assessed using the Physiotherapy Evidence Database (PEDro) scale. A narrative synthesis focusing on pain and function outcomes was performed in studies with a mean sample size of at least 46 participants per treatment arm. Results: 33 publications (28 studies), 82% with PEDro ratings of good or excellent, were eligible for narrative synthesis: 23 studies evaluated knee OA; one knee OA or chronic low back pain; two knee or hip OA; one hip OA only; and one thumb OA. No studies identified a dose, duration or type of exercise that resulted in better pain or function outcomes. Core treatments generally showed modest benefits compared to no or minimal intervention controls. Conclusions: Rehabilitation research continues to be focused on the knee. Most studies are not adequately powered to assess pain efficacy. Further work is needed to better account for contextual effects, identify treatment responder characteristics, understand treatment mechanisms, and implement guideline care.

Published
2023

30. Smaller intercondylar notch size and smaller ACL volume increase posterior cruciate ligament rupture risk

Author

van Kuijk, K. S.R., Reijman, M., Bierma-Zeinstra, S. M.A., Meuffels, D. E., van Kuijk, K. S.R., Reijman, M., Bierma-Zeinstra, S. M.A., and Meuffels, D. E.

Abstract

Purpose: Little is known about risk factors for sustaining a posterior cruciate ligament (PCL) rupture. Identifying risk factors is the first step in preventing a PCL rupture from occurring. The morphology of the knee in patients who ruptured their PCL may differ from that of control patients. The hypothesis was that the intercondylar notch dimensions, 3-D volumes of the intercondylar notch and, the 3-D volumes of both the ACL and the PCL were correlated to the presence of a PCL rupture. Methods: The magnetic resonance imaging (MRI) scans of 30 patients with a proven PCL rupture were compared to 30 matched control patients with proven intact ACL and PCL. Control patients were selected from patients with knee trauma during sports but without cruciate ligament injury. Patients have been matched for age, height, weight, BMI, and sex. The volumes of the intercondylar notch and both the ACL and PCL were measured on 3D reconstructions. Second, the bicondylar width, the notch width, and the notch width index were measured of all subjects. The relationship between our measurements and the presence of a PCL rupture was analysed. Results: The results show a significant difference in the volumes of the intercondylar notch and the ACL between patients with a ruptured PCL and control patients. Patients with a PCL rupture have smaller intercondylar notch volumes and smaller ACL volumes. There were no significant differences in the bicondylar width, notch width, and notch width index. In the control patients, a significant correlation between the volume of the PCL and the volume of the ACL was found (0.673, p < 0.001). Conclusion: Patients with a PCL rupture have smaller intercondylar volumes and smaller ACL volumes when compared to control patients. Second, patients with smaller ACL volumes have smaller PCL volumes. This study shows, for the first time, that there are significant size and volume differences in the shape of the knee between patients with a PCL rupture and co

Published
2023

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