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16 results on '"Reichold, Johannes"'

8. Human-Machine Interaction in Care-Education

Author

Reichold, Johannes, Agrawal, Ankita, Thurlings, Marieke, Cohen, Iris, Weber-Fiori, Barbara, Rölle, Anita, Hassan, Muneeb, Dürr, Maximilian, Pfeil, Ulrike, Pape, Anna-Antonia, Grünert, Gerd, Schmidt, Artur, Pfeil, Markus, Fäßler, Victor, Jauch, Volker, Reiterer, Harald, Winter, Maik, Ertel, Wolfgang, and Eberhardt, Jörg

Subjects
situated learning, machine learning, cognitive load, motion capture, ddc:004, Embodied cognition
Abstract

The research project ERTRAG, funded by the German Federal Ministry of Education and Research, aims to develop a virtual ergonomics trainer for nursing as well as elderly care education. The trainer supports apprentices conducting the care related motions in an ergonomically correct fashion, thereby helping to prevent work-related health problems such as dorsal pain. The user interface of the ERTRAG system for instruction and feedback adjusts to the individual preferences and needs, as well as to the current cognitive state of the user. This adaptive, highly customizable human-machine interaction fosters effective and long-lasting learning. published

Published
2017
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10. Cerebral Blood Flow Modeling in Realistic Cortical Microvascular Networks

Author

Reichold, Johannes, Jenny, Patrick, Buck, Alfred, University of Zurich, and Reichold, J

Subjects
SIGNAL TRANSDUCTION (NEUROLOGY), HIRNABBILDUNGSVERFAHREN (NEUROLOGIE), HIRNKREISLAUF + HIRNDURCHBLUTUNG + ZEREBRALE BLUTGEFÄSSE (NEUROLOGIE), ANIMAL MODELS IN MEDICINE, 10050 Institute of Pharmacology and Toxicology, BRAIN CIRCULATION + CEREBRAL PERFUSION + CEREBRAL BLOOD VESSELS (NEUROLOGY), CEREBRAL METABOLISM (PHYSIOLOGY), TIERISCHE MODELLE IN DER MEDIZIN, HIRNSTOFFWECHSEL (PHYSIOLOGIE), BRAIN IMAGING (NEUROLOGY), SIGNALTRANSDUKTION (NEUROLOGIE), 610 Medicine & health, UZHDISS UZH Dissertations, 570 Life sciences, biology, ddc:610, Medical sciences, medicine
Published
2011

15. The Microvascular System of the Striate and Extrastriate Visual Cortex of the Macaque

Author

Weber, Bruno, Keller, Anna Lena, Reichold, Johannes, Logothetis, Nikos K., Weber, Bruno, Keller, Anna Lena, Reichold, Johannes, and Logothetis, Nikos K.

Abstract

In functional neuroimaging, neurovascular coupling is used to generate maps of hemodynamic changes that are assumed to be surrogates of regional neural activation. The aim of this study was to characterize the microvascular system of the primate cortex as a basis for understanding the constraints imposed on a region's hemodynamic response by the vascular architecture, density, as well as area- and layer-specific variations. In the macaque visual cortex, an array of anatomical techniques has been applied, including corrosion casts, immunohistochemistry, and cytochrome oxidase (COX) staining. Detailed measurements of regional vascular length density, volume fraction, and surface density revealed a similar vascularization in different visual areas. Whereas the lower cortical layers showed a positive correlation between the vascular and cell density, this relationship was very weak in the upper layers. Synapse density values taken from the literature also displayed a very moderate correlation with the vascular density. However, the vascular density was strongly correlated with the steady-state metabolic demand as measured by COX activity. This observation suggests that although the number of neurons and synapses determines an upper bound on an area's integrative capacity, its vascularization reflects the neural activity of those subpopulations that represent a "default” mode of brain steady state

16. The impact of capillary dilation on the distribution of red blood cells in artificial networks.

Author

Schmid F, Reichold J, Weber B, and Jenny P

Subjects
Animals, Blood Flow Velocity, Capillaries anatomy & histology, Hematocrit, Humans, Numerical Analysis, Computer-Assisted, Oxygen blood, Regional Blood Flow, Capillaries physiology, Computer Simulation, Erythrocytes physiology, Models, Anatomic, Models, Cardiovascular, Vasodilation
Abstract

Recent studies suggest that pericytes around capillaries are contractile and able to alter the diameter of capillaries. To investigate the effects of capillary dilation on network dynamics, we performed simulations in artificial capillary networks of different sizes and complexities. The unequal partition of hematocrit at diverging bifurcations was modeled by assuming that each red blood cell (RBC) enters the branch with the faster instantaneous flow. Network simulations with and without RBCs were performed to investigate the effect of local dilations. The results showed that the increase in flow rate due to capillary dilation was less when the effects of RBCs are included. For bifurcations with sufficient RBCs in the parent vessel and nearly equal flows in the branches, the flow rate in the dilated branch did not increase. Instead, a self-regulation of flow was observed due to accumulation of RBCs in the dilated capillary. A parametric study was performed to examine the dependence on initial capillary diameter, dilation factor, and tube hematocrit. Furthermore, the conditions needed for an efficient self-regulation mechanism are discussed. The results support the hypothesis that RBCs play a significant role for the fluid dynamics in capillary networks and that it is crucial to consider the blood flow rate and the distribution of RBCs to understand the supply of oxygen in the vasculature. Furthermore, our results suggest that capillary dilation/constriction offers the potential of being an efficient mechanism to alter the distribution of RBCs locally and hence could be important for the local regulation of oxygen delivery., (Copyright © 2015 the American Physiological Society.)

Published
2015
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