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114 results on '"Reichel, V."'

3. Macroeconomic forecasting in the euro area using predictive combinations of DSGE models

Author

Čapek, J., Crespo Cuaresma, J., Hauzenberger, N., Reichel, V., Čapek, J., Crespo Cuaresma, J., Hauzenberger, N., and Reichel, V.

Abstract

We provide a comprehensive assessment of the predictive power of combinations of dynamic stochastic general equilibrium (DSGE) models for GDP growth, inflation, and the interest rate in the euro area. We employ a battery of static and dynamic pooling weights based on Bayesian model averaging principles, prediction pools, and dynamic factor representations, and entertain six different DSGE specifications and five prediction weighting schemes. Our results indicate that exploiting mixtures of DSGE models produces competitive forecasts compared to individual specifications for both point and density forecasts over the last three decades. Although these combinations do not tend to systematically achieve superior forecast performance, we find improvements for particular periods of time and variables when using prediction pooling, dynamic model averaging, and combinations of forecasts based on Bayesian predictive synthesis.

Published
2022
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8. Influence of pedestal diameter on mode instabilities in Yb/Ce/Al-doped fibers

Author

Möller, F., primary, Distler, V., additional, Walbaum, T., additional, Haarlammert, N., additional, Nold, J., additional, Schreiber, T., additional, Unger, S., additional, Reichel, V., additional, Kobelke, J., additional, Bierlich, J., additional, Schwuchow, A., additional, Eschrich, T., additional, Leich, M., additional, Wondraczek, K., additional, and Tünnermann, A., additional

Published
2020
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13. Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus

Author

Reichel, V., Klas, J., Fricker, G., and Masereeuw, R.

Subjects
Membrane transport and intracellular motility [NCMLS 5]
Abstract

Contains fulltext : 88597.pdf (Publisher’s version ) (Closed access) The choroid plexuses (CP) are responsible for transport of micronutrients into brain and clearance of toxic compounds, in addition to its barrier function and production of CSF. Multidrug resistance-associated protein (Mrp) 4 is one transport protein highly expressed in CP tissue and is characterized as a versatile pump for toxicants and signalling molecules. Aim of the study was to determine transport characteristics of a fluorescent cAMP analog in rat CP and to define whether fluo-cAMP can be used for analyses of function, substrate/inhibitor specificity and regulation of Mrp4. Confocal imaging was used to analyze transport mechanisms in absence and presence of various modulators of organic anion transport in freshly isolated and functionally intact CP. Fluo-cAMP transport was saturable, selective, concentrative and metabolism-dependent, following an active two-step mechanism composed of apical uptake into epithelial cells and basolateral efflux. Uptake included a Na(+) -dependent and a Na(+) -independent component and was inhibited by estrone sulfate, taurocholate and sildenafil indicating involvement of organic anion transporting polypeptide Oatp1a5. Efflux was composed of an indirect Na(+) -dependent component and a component inhibitable by, for example, the MRP4 substrates/inhibitors, sulindac sulfide and 4-(2-aminoethyl) benzenesulfonyl fluoride. Therefore, fluo-cAMP can be used as fluorescent model compound for studying involvement of Mrp4 in signalling pathways and neuroprotection in CP. 01 oktober 2010

Published
2010

15. Transport of a fluorescent cAMP analog in teleost proximal tubules.

Author

Reichel, V., Masereeuw, R., Heuvel, J.J.M.W. van den, Miller, D.S., Fricker, G., Reichel, V., Masereeuw, R., Heuvel, J.J.M.W. van den, Miller, D.S., and Fricker, G.

Abstract

Contains fulltext : 52448.pdf (publisher's version ) (Closed access), Previous studies have shown that killifish (Fundulus heteroclitus) renal proximal tubules express a luminal membrane transporter that is functionally and immunologically analogous to the mammalian multidrug resistance-associated protein isoform 2 (Mrp2, ABCC2). Here we used confocal microscopy to investigate in killifish tubules the transport of a fluorescent cAMP analog (fluo-cAMP), a putative substrate for Mrp2 and Mrp4 (ABCC4). Steady-state luminal accumulation of fluo-cAMP was concentrative, specific, and metabolism-dependent, but not reduced by high K+ medium or ouabain. Transport was not affected by p-aminohippurate (organic anion transporter inhibitor) or p-glycoprotein inhibitor (PSC833), but cell-to-lumen transport was reduced in a concentration-dependent manner by Mrp inhibitor MK571, leukotriene C4 (LTC4), azidothymidine (AZT), cAMP, and adefovir; the latter two compounds are Mrp4 substrates. Although MK571 and LTC4 reduced transport of the Mrp2 substrate fluorescein-methotrexate (FL-MTX), neither cAMP, adefovir, nor AZT affected FL-MTX transport. Fluo-cAMP transport was not reduced when tubules were exposed to endothelin-1, Na nitroprusside (an nitric oxide generator) or phorbol ester (PKC activator), all of which signal substantial reductions in cell-to-lumen FL-MTX transport. Fluo-cAMP transport was reduced by forskolin, and this reduction was blocked by the PKA inhibitor H-89. Finally, in membrane vesicles from Spodoptera frugiperda (Sf9) cells containing human MRP4, ATP-dependent and specific uptake of fluo-cAMP could be demonstrated. Thus, based on inhibitor specificity and regulatory signaling, cell-to-lumen transport of fluo-cAMP in killifish renal tubules is mediated by a transporter distinct from Mrp2, presumably a teleost form of Mrp4.

Published
2007

20. Polarization mode dispersion measurements on long buried cables

Author

Reichel, V., Vobian, J., and Gisin, Nicolas

Subjects
ddc:500.2
Abstract

This paper describes the polarization mode dispersion (PMD) measurements of long standard fibers, dispersion-shifted (DS-) and dispersion-flattened (DF-) fibers uncabled on bobbins and in cables installed in the test links Berlin IV (18 km long) and Berlin VI (22.6 km). The PMD is measured with the aid of the interferometric technique, using a Michelson-interferometer. This method is not restricted to long fibers with low birefringence, it can be used to measuring the PMD and group beatlength of short high-birefringent fibers with a high accuracy. It will be shown that the cabling procedure increases the PMD values considerably, up to one order of magnitude.

Published
1993

27. Comparison of different materials for laser active fibers

Author

Reichel, V., primary, Leich, M., additional, Grimm, S., additional, Unger, S., additional, Schwuchow, A., additional, Kirchhof, J., additional, Langner, A., additional, Schotz, G., additional, Such, M., additional, Kayser, T., additional, Krause, V., additional, and Rehmann, G., additional

Published
2008
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31. High average power femtosecond fiber CPA system

Author

Liem, A., primary, Limpert, J., additional, Schreiber, T., additional, Nolte, S., additional, Zellmer, H., additional, Tünnermann, A., additional, Reichel, V., additional, Unger, S., additional, Jetschke, S., additional, and Müller, H.-R., additional

Published
2002
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