672 results on '"Regan T."'
Search Results
2. AB1647-PARE LIVING WITH LUPUS IN IRELAND-RESULTS OF A PATIENT SURVEY
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Regan, T., primary and O Leary, G., additional
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- 2024
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3. Nurses’ Use of Chiropractic for Relief of Back and Neck Pain
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Vellan, Regan T, primary and Gantt, Laura, additional
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- 2024
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4. A general phase noise relationship for four-wave mixing
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Anthur, Aravind P., Watts, Regan T., Huynh, Tam N., Venkitesh, Deepa, and Barry, Liam P.
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Physics - Optics - Abstract
We propose and verify the use of the power spectral density of the FM noise spectrum to study the phase noise relationship between the four-wave mixing components., Comment: 5 pages, 3 figures
- Published
- 2013
5. Structured decision making to navigate trade‐offs between multiple conservation values in threatened grasslands
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Regan, T. J., primary, MacHunter, J., additional, Sinclair, S. J., additional, Bruce, M. J., additional, Neil, J., additional, Parker, E., additional, and Nam, B., additional
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- 2023
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6. Ask a Local: Improving the Public Pricing of Land Titles in Urban Tanzania
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Manara, M and Regan, T
- Subjects
Economics and Econometrics ,Social Sciences (miscellaneous) - Abstract
Information on willingness-to-pay is key for public pricing and allocation of services but not easily collected. Studying land titles in Dar-es-Salaam, we ask whether local leaders know and will reveal plot owners' willingness-to-pay. We randomly assign leaders to predict under different settings then elicit owners' actual willingness-to-pay. Demand is substantial, but below exorbitant fees. Leaders can predict the aggregate demand curve and distinguish variation across owners. Predictions worsen when used to target subsidies, but adding cash incentives mitigates this. Finally, we demonstrate that leader-elicited information can improve the public pricing of title deeds, raising uptake while maintaining public funds.
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- 2022
7. Phase-noise compensated carriers from an optical frequency comb allowing terabit transmission.
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Wolfgang Freude, Jörg Pfeifle, Regan T. Watts, I. Shkarban, Stefan Wolf 0004, Vidak Vujicic, Pascal Landais, N. Chimot, S. Joshi, Kamel Merghem, Cosimo Calo, M. Weber, Abderrahim Ramdane, Francois Lelarge, Liam P. Barry, and Christian Koos
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- 2015
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8. Screening, brief intervention, and referral to treatment (SBIRT) for cannabis: A scoping review
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Gette, J.A., primary, Regan, T., additional, and Schumacher, J.A., additional
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- 2023
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9. Involvement of informal caregivers in supporting patients with COPD: a review of intervention studies
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Bryant J, Mansfield E, Boyes AW, Waller A, Sanson-Fisher R, and Regan T
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Chronic obstructive pulmonary disease ,carer ,support persons ,intervention studies ,Diseases of the respiratory system ,RC705-779 - Abstract
Jamie Bryant,1,2 Elise Mansfield,1,2 Allison W Boyes,1,2 Amy Waller,1,2 Rob Sanson-Fisher,1,2 Timothy Regan1,2 1Health Behaviour Research Group, Priority Research Centre for Health Behaviour, 2Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia Abstract: Caregivers of individuals with COPD have a key role in maintaining patient adherence and optimizing patient function. However, no systematic review has examined how the caregiver role has been operationalized in interventions to improve outcomes of individuals with COPD or the quality or effectiveness of these interventions. The aims of this review were to 1) determine whether caregivers have been involved as part of interventions to improve outcomes of individuals with COPD; 2) determine the risk of bias within included intervention studies; and 3) examine the effectiveness of interventions that have involved caregivers in improving outcomes of individuals with COPD. The electronic databases of Medline, Embase, PsycINFO, and Cochrane Library were searched from January 2000 to November 2015. Experimental studies testing interventions that involved a caregiver to improve COPD patient outcomes were eligible. Nine studies involving caregivers met inclusion criteria. No studies reported any intervention components targeted solely at caregivers, with most instead including caregivers in dyadic or group education sessions about COPD delivered by health care professionals. The risk of bias identified in included studies was mixed. Seven of the nine studies were effective in improving a broad range of outcomes. These findings highlight that there is an urgent need for methodologically rigorous interventions to examine the effectiveness of strategies to assist caregivers to provide direct care, encourage adherence to health care provider recommendations, act as a health care advocate, and provide emotional and psychosocial support to individuals with COPD. Keywords: COPD, carer, support persons, intervention studies
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- 2016
10. Quantum dash passively mode-locked lasers for Tbit/s data interconnects.
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Vidak Vujicic, Cosimo Calo, Regan T. Watts, Francois Lelarge, Colm Browning, Kamel Merghem, Anthony Martinez, Abderrahim Ramdane, and Liam P. Barry
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- 2015
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11. Simultaneous phase noise reduction of 30 comb lines from a quantum-dash mode-locked laser diode enabling coherent tbit/s data transmission.
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Jörg Pfeifle, Regan T. Watts, I. Shkarban, Stefan Wolf 0004, Vidak Vujicic, Pascal Landais, N. Chimot, S. Joshi, Kamel Merghem, Cosimo Calo, M. Weber, Abderrahim Ramdane, Francois Lelarge, Liam P. Barry, Wolfgang Freude, and Christian Koos
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- 2015
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12. Choice of biodiversity index drives optimal fire management decisions
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Giljohann, K. M., McCarthy, M. A., Kelly, L. T., and Regan, T. J.
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- 2015
13. Penalty-free wavelength conversion with variable channel separation using gain-switched comb source
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Anthur, Aravind P., Watts, Regan T., Zhou, Rui, Anandarajah, Prince, Venkitesh, Deepa, and Barry, Liam P.
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- 2014
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14. Smoky homes: Gender, socioeconomic and housing disparities in second hand tobacco smoke (SHS) exposure in a large population-based Australian cohort
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Bonevski, B., Paul, C., Jones, A., Bisquera, A., and Regan, T.
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- 2014
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15. Detailed experimental phase noise characterization of Y-branch lasers for use in coherent communication systems.
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Regan T. Watts, Kai Shi 0003, Yonglin Yu, and Liam P. Barry
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- 2013
16. Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions
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Meek, S., Watson, T., Eory, L., McFarlane, G., Wynne, F.J., McCleary, S., Dunn, L.E.M., Charlton, E.M., Craig, C., Shih, B., Regan, T., Taylor, R., Sutherland, L., Gossner, A., Chintoan-Uta, C., Fletcher, S., Beard, P.M., Hassan, M.A., Grey, F., Hope, J.C., Stevens, M.P., Nowak-Imialek, M., Niemann, H., Ross, P.J., Tait-Burkard, C., Brown, S.M., Lefevre, L., Thomson, G., McColl, B.W., Lawrence, A.B., Archibald, A.L., Steinbach, F., Crooke, H.R., Gao, X., Liu, P., Burdon, T., Meek, S., Watson, T., Eory, L., McFarlane, G., Wynne, F.J., McCleary, S., Dunn, L.E.M., Charlton, E.M., Craig, C., Shih, B., Regan, T., Taylor, R., Sutherland, L., Gossner, A., Chintoan-Uta, C., Fletcher, S., Beard, P.M., Hassan, M.A., Grey, F., Hope, J.C., Stevens, M.P., Nowak-Imialek, M., Niemann, H., Ross, P.J., Tait-Burkard, C., Brown, S.M., Lefevre, L., Thomson, G., McColl, B.W., Lawrence, A.B., Archibald, A.L., Steinbach, F., Crooke, H.R., Gao, X., Liu, P., and Burdon, T.
- Abstract
BACKGROUND: Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and plays a major role in shaping the adaptive immune response. However, this phagocyte is a target and host for many pathogens. Understanding the molecular basis of interactions between macrophages and pathogens is therefore crucial for the development of effective strategies to combat important infectious diseases. RESULTS: We explored how porcine pluripotent stem cells (PSCs) can provide a limitless in vitro supply of genetically and experimentally tractable macrophages. Porcine PSC-derived macrophages (PSCdMs) exhibited molecular and functional characteristics of ex vivo primary macrophages and were productively infected by pig pathogens, including porcine reproductive and respiratory syndrome virus (PRRSV) and African swine fever virus (ASFV), two of the most economically important and devastating viruses in pig farming. Moreover, porcine PSCdMs were readily amenable to genetic modification by CRISPR/Cas9 gene editing applied either in parental stem cells or directly in the macrophages by lentiviral vector transduction. CONCLUSIONS: We show that porcine PSCdMs exhibit key macrophage characteristics, including infection by a range of commercially relevant pig pathogens. In addition, genetic engineering of PSCs and PSCdMs affords new opportunities for functional analysis of macrophage biology in an important livestock species. PSCs and differentiated derivatives should therefore represent a useful and ethical experimental platform to investigate the genetic and molecular basis of host-pathogen interactions in pigs, and also have wider applications in livestock.
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- 2022
17. Multi-terabit/s transmission using chip-scale frequency comb sources.
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Christian Koos, Tobias J. Kippenberg, Liam P. Barry, Larry R. Dalton, Abderrahim Ramdane, Francois Lelarge, Wolfgang Freude, Juned N. Kemal, Pablo Marin, Stefan Wolf 0004, P. Trocha, Jörg Pfeifle, C. Weimann, Matthias Lauermann, T. Herr, Victor Brasch, Regan T. Watts, Delwin L. Elder, A. Martinez, Vivek Panapakkam, and N. Chimot
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- 2016
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18. Left Ventricular Diastolic Dysfunction in Diabetic or Hypertensive Subjects: Role of Collagen Alterations
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Regan, T. J., Jyothirmayi, G. N., Laham, C., Jain, A., Angel, Aubie, editor, Dhalla, Naranjan, editor, Pierce, Grant, editor, and Singal, Pawan, editor
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- 2001
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19. Time-resolved chirp measurement for 100GBaud test systems using an ideal frequency discriminator
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Watts, Regan T., Shi, Kai, and Barry, Liam P.
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- 2012
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20. Characterization of 40-Gbit/s pulses generated using a lithium niobate modulator at 1550 nm using frequency resolved optical gating.
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Benn C. Thomsen, Douglas A. Reid, Regan T. Watts, Liam P. Barry, and John D. Harvey
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- 2004
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21. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
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Brown, P, Zhou, Y, Tan, A, El-Esawi, M, Liehr, T, Blanck, O, Gladue, D, Almeida, G, Cernava, T, Sorzano, C, Yeung, A, Engel, M, Chandrasekaran, A, Muth, T, Staege, M, Daulatabad, S, Widera, D, Zhang, J, Meule, A, Honjo, K, Pourret, O, Yin, C, Zhang, Z, Cascella, M, Flegel, W, Goodyear, C, van Raaij, M, Bukowy-Bieryllo, Z, Campana, L, Kurniawan, N, Lalaouna, D, Huttner, F, Ammerman, B, Ehret, F, Cobine, P, Tan, E, Han, H, Xia, W, Mccrum, C, Dings, R, Marinello, F, Nilsson, H, Nixon, B, Voskarides, K, Yang, L, Costa, V, Bengtsson-Palme, J, Bradshaw, W, Grimm, D, Kumar, N, Martis, E, Prieto, D, Sabnis, S, Amer, S, Liew, A, Perco, P, Rahimi, F, Riva, G, Zhang, C, Devkota, H, Ogami, K, Basharat, Z, Fierz, W, Siebers, R, Tan, K, Boehme, K, Brenneisen, P, Brown, J, Dalrymple, B, Harvey, D, Ng, G, Werten, S, Bleackley, M, Dai, Z, Dhariwal, R, Gelfer, Y, Hartmann, M, Miotla, P, Tamaian, R, Govender, P, Gurney-Champion, O, Kauppila, J, Zhang, X, Echeverria, N, Subhash, S, Sallmon, H, Tofani, M, Bae, T, Bosch, O, Cuiv, P, Danchin, A, Diouf, B, Eerola, T, Evangelou, E, Filipp, F, Klump, H, Kurgan, L, Smith, S, Terrier, O, Tuttle, N, Ascher, D, Janga, S, Schulte, L, Becker, D, Browngardt, C, Bush, S, Gaullier, G, Ide, K, Meseko, C, Werner, G, Zaucha, J, Al-Farha, A, Greenwald, N, Popoola, S, Rahman, S, Xu, J, Yang, S, Hiroi, N, Alper, O, Baker, C, Bitzer, M, Chacko, G, Debrabant, B, Dixon, R, Forano, E, Gilliham, M, Kelly, S, Klempnauer, K, Lidbury, B, Lin, M, Lynch, I, Ma, W, Maibach, E, Mather, D, Nandakumar, K, Ohgami, R, Parchi, P, Tressoldi, P, Xue, Y, Armitage, C, Barraud, P, Chatzitheochari, S, Coelho, L, Diao, J, Doxey, A, Gobet, A, Hu, P, Kaiser, S, Mitchell, K, Salama, M, Shabalin, I, Song, H, Stevanovic, D, Yadollahpour, A, Zeng, E, Zinke, K, Alimba, C, Beyene, T, Cao, Z, Chan, S, Gatchell, M, Kleppe, A, Piotrowski, M, Torga, G, Woldesemayat, A, Cosacak, M, Haston, S, Ross, S, Williams, R, Wong, A, Abramowitz, M, Effiong, A, Lee, S, Abid, M, Agarabi, C, Alaux, C, Albrecht, D, Atkins, G, Beck, C, Bonvin, A, Bourke, E, Brand, T, Braun, R, Bull, J, Cardoso, P, Carter, D, Delahay, R, Ducommun, B, Duijf, P, Epp, T, Eskelinen, E, Fallah, M, Farber, D, Fernandez-Triana, J, Feyerabend, F, Florio, T, Friebe, M, Furuta, S, Gabrielsen, M, Gruber, J, Grybos, M, Han, Q, Heinrich, M, Helantera, H, Huber, M, Jeltsch, A, Jiang, F, Josse, C, Jurman, G, Kamiya, H, de Keersmaecker, K, Kristiansson, E, de Leeuw, F, Li, J, Liang, S, Lopez-Escamez, J, Lopez-Ruiz, F, Marchbank, K, Marschalek, R, Martin, C, Miele, A, Montagutelli, X, Morcillo, E, Nicoletti, R, Niehof, M, O'Toole, R, Ohtomo, T, Oster, H, Palma, J, Paterson, R, Peifer, M, Portilla, M, Portillo, M, Pritchard, A, Pusch, S, Raghava, G, Roberts, N, Ross, K, Schuele, B, Sergeant, K, Shen, J, Stella, A, Sukocheva, O, Uversky, V, Vanneste, S, Villet, M, Viveiros, M, Vorholt, J, Weinstock, C, Yamato, M, Zabetakis, I, Zhao, X, Ziegler, A, Aizat, W, Atlas, L, Bridges, K, Chakraborty, S, Deschodt, M, Domingues, H, Esfahlani, S, Falk, S, Guisado, J, Kane, N, Kueberuwa, G, Lau, C, Liang, D, Liu, E, Luu, A, Ma, C, Ma, L, Moyer, R, Norris, A, Panthee, S, Parsons, J, Peng, Y, Pinto, I, Reschke, C, Sillanpaa, E, Stewart, C, Uhle, F, Yang, H, Zhou, K, Zhu, S, Ashry, M, Bergsland, N, Berthold, M, Chen, C, Colella, V, Cuypers, M, Eskew, E, Fan, X, Gajda, M, Gonzalezlez-Prendes, R, Goodin, A, Graham, E, Groen, E, Gutierrez-Sacristan, A, Habes, M, Heffler, E, Higginbottom, D, Janzen, T, Jayaraman, J, Jibb, L, Jongen, S, Kinyanjui, T, Koleva-Kolarova, R, Li, Z, Liu, Y, Lund, B, Lussier, A, Mier, P, Moore, M, Nagler, K, Orme, M, Pearson, J, Prajapati, A, Saito, Y, Troder, S, Uchendu, F, Verloh, N, Voutchkova, D, Abu-Zaid, A, Bakkach, J, Baumert, P, Dono, M, Hanson, J, Herbelet, S, Hobbs, E, Kulkarni, A, Liu, S, Loft, N, Reddan, T, Senghore, T, Vindin, H, Xu, H, Bannon, R, Chen, B, Cheung, J, Cooper, J, Esnakula, A, Feghali, K, Ghelardi, E, Gnasso, A, Horbar, J, Lai, H, Ma, R, Pan, Z, Peres, M, Pranata, R, Seow, E, Sydes, M, Testoni, I, Westermair, A, Yang, Y, Afnan, M, Albiol, J, Albuquerque, L, Amir, S, Amiya, E, Amorim, R, An, Q, Andersen, S, Aplin, J, Argyropoulos, C, Asmann, Y, Assaeed, A, Atanasov, A, Atchison, D, Avery, S, Avillach, P, Baade, P, Backman, L, Badie, C, Baldi, A, Ball, E, Bardot, O, Barnett, A, Basner, M, Batra, J, Bazanova, O, Beale, A, Beddoe, T, Bell, M, Berezikov, E, Berners-Price, S, Bernhardt, P, Berry, E, Bessa, T, Billington, C, Birch, J, Blakely, R, Blaskovich, M, Blum, R, Boelaert, M, Bogdanos, D, Bosch, C, Bourgoin, T, Bouvard, D, Boykin, L, Bradley, G, Braun, D, Brownlie, J, Bruhl, A, Burt, A, Butler, L, Byrareddy, S, Byrne, H, Cabantous, S, Calatayud, S, Candal, E, Carlson, K, Casillas, S, Castelvetro, V, Caswell, P, Cavalli, G, Cerovsky, V, Chagoyen, M, Chen, D, Chen, H, Chen, J, Chen, Y, Cheng, C, Cheng, J, Chinapaw, M, Chinopoulos, C, Cho, W, Chong, L, Chowdhury, D, Chwalibog, A, Ciresi, A, Cockcroft, S, Conesa, A, Cook, P, Cooper, D, Coqueret, O, Corea, E, Costa, A, Costa, E, Coupland, C, Crawford, S, Cruz, A, Cui, H, Cui, Q, Culver, D, D'Angiulli, A, Dahms, T, Daigle, F, Dalgleish, R, Danielsen, H, Darras, S, Davidson, S, Day, D, Degirmenci, V, Demaison, L, Devriendt, K, Ding, J, Dogan, Y, Dong, X, Donner, C, Dressick, W, Drevon, C, Duan, H, Ducho, C, Dumaz, N, Dwarakanath, B, Ebell, M, Eisenhardt, S, Elkum, N, Engel, N, Erickson, T, Fairhead, M, Faville, M, Fejzo, M, Festa, F, Feteira, A, Flood-Page, P, Forsayeth, J, Fox, S, Franks, S, Frentiu, F, Frilander, M, Fu, X, Fujita, S, Galea, I, Galluzzi, L, Gani, F, Ganpule, A, Garcia-Alix, A, Gedye, K, Giordano, M, Giunta, C, Gleeson, P, Goarant, C, Gong, H, Gora, D, Gough, M, Goyal, R, Graham, K, Grande-Perez, A, Graves, P, Greidanus, H, Grice, D, Grunau, C, Gumulya, Y, Guo, Y, Gurevich, V, Gusev, O, Hacker, E, Hage, S, Hagen, G, Hahn, S, Haller, D, Hammerschmidt, S, Han, J, Han, R, Handfield, M, Hapuarachchi, H, Harder, T, Hardingham, J, Heck, M, Heers, M, Hew, K, Higuchi, Y, Hilaire, C, Hilton, R, Hodzic, E, Hone, A, Hongoh, Y, Hu, G, Huber, H, Hueso, L, Huirne, J, Hurt, L, Idborg, H, Ikeo, K, Ingley, E, Jakeman, P, Jensen, A, Jia, H, Jia, S, Jiang, J, Jiang, X, Jin, Y, Jo, D, Johnson, A, Johnston, M, Jonscher, K, Jorens, P, Jorgensen, J, Joubert, J, Jung, S, Junior, A, Kahan, T, Kamboj, S, Kang, Y, Karamanos, Y, Karp, N, Kelly, R, Kenna, R, Kennedy, J, Kersten, B, Khalaf, R, Khalid, J, Khatlani, T, Khider, T, Kijanka, G, King, S, Kluz, T, Knox, P, Kobayashi, T, Koch, K, Kohonen-Corish, M, Kong, X, Konkle-Parker, D, Korpela, K, Kostrikis, L, Kraiczy, P, Kratz, H, Krause, G, Krebsbach, P, Kristensen, S, Kumari, P, Kunimatsu, A, Kurdak, H, Kwon, Y, Lachat, C, Lagisz, M, Laky, B, Lammerding, J, Lange, M, Larrosa, M, Laslett, A, Laverman, G, Leclair, E, Lee, K, Lee, M, Li, G, Lieb, K, Lim, Y, Lindsey, M, Line, P, Liu, D, Liu, F, Liu, H, Lloyd, V, Lo, T, Locci, E, Loidl, J, Lorenzen, J, Lorkowski, S, Lovell, N, Lu, H, Lu, W, Lu, Z, Luengo, G, Lundh, L, Lysy, P, Mabb, A, Mack, H, Mackey, D, Mahdavi, S, Maher, P, Maher, T, Maity, S, Malgrange, B, Mamoulakis, C, Mangoni, A, Manke, T, Manstead, A, Mantalaris, A, Marsal, J, Marschall, H, Martin, F, Martinez-Raga, J, Martinez-Salas, E, Mathieu, D, Matsui, Y, Maza, E, Mccutcheon, J, Mckay, G, Mcmillan, B, Mcmillan, N, Meads, C, Medina, L, Merrick, B, Metzger, D, Meunier, F, Michaelis, M, Micheau, O, Mihara, H, Mintz, E, Mizukami, T, Moalic, Y, Mohapatra, D, Monteiro, A, Montes, M, Moran, J, Morozov, S, Mort, M, Murai, N, Murphy, D, Murphy, S, Murray, S, Naganawa, S, Nammi, S, Nasios, G, Natoli, R, Nguyen, F, Nicol, C, van Nieuwerburgh, F, Nilsen, E, Nobile, C, O'Mahony, M, Ohlsson, S, Olatunbosun, O, Olofsson, P, Ortiz, A, Ostrikov, K, Otto, S, Outeiro, T, Ouyang, S, Paganoni, S, Page, A, Palm, C, Paradies, Y, Parsons, M, Parsons, N, Pascal, P, Paul, E, Peckham, M, Pedemonte, N, Pellizzon, M, Petrelli, M, Pichugin, A, Pinto, C, Plevris, J, Pollesello, P, Polz, M, Ponti, G, Porcelli, P, Prince, M, Quinn, G, Quinn, T, Ramula, S, Rappsilber, J, Rehfeldt, F, Reiling, J, Remacle, C, Rezaei, M, Riddick, E, Ritter, U, Roach, N, Roberts, D, Robles, G, Rodrigues, T, Rodriguez, C, Roislien, J, Roobol, M, Rowe, A, Ruepp, A, van Ruitenbeek, J, Rust, P, Saad, S, Sack, G, Santos, M, Saudemont, A, Sava, G, Schrading, S, Schramm, A, Schreiber, M, Schuler, S, Schymkowitz, J, Sczyrba, A, Seib, K, Shi, H, Shimada, T, Shin, J, Shortt, C, Silveyra, P, Skinner, D, Small, I, Smeets, P, So, P, Solano, F, Sonenshine, D, Song, J, Southall, T, Speakman, J, Srinivasan, M, Stabile, L, Stasiak, A, Steadman, K, Stein, N, Stephens, A, Stewart, D, Stine, K, Storlazzi, C, Stoynova, N, Strzalka, W, Suarez, O, Sultana, T, Sumant, A, Summers, M, Sun, G, Tacon, P, Tanaka, K, Tang, H, Tanino, Y, Targett-Adams, P, Tayebi, M, Tayyem, R, Tebbe, C, Telfer, E, Tempel, W, Teodorczyk-Injeyan, J, Thijs, G, Thorne, S, Thrift, A, Tiffon, C, Tinnefeld, P, Tjahjono, D, Tolle, F, Toth, E, Del Tredici, A, Tsapas, A, Tsirigotis, K, Turak, A, Tzotzos, G, Udo, E, Utsumi, T, Vaidyanathan, S, Vaillant, M, Valsesia, A, Vandenbroucke, R, Veiga, F, Vendrell, M, Vesk, P, Vickers, P, Victor, V, Villemur, R, Vohl, M, Voolstra, C, Vuillemin, A, Wakelin, S, Waldron, L, Walsh, L, Wang, A, Wang, F, Wang, Y, Watanabe, Y, Weigert, A, Wen, J, Wham, C, White, E, Wiener, J, Wilharm, G, Wilkinson, S, Willmann, R, Wilson, C, Wirth, B, Wojan, T, Wolff, M, Wong, B, Wu, T, Wuerbel, H, Xiao, X, Xu, D, Xue, B, Yalcin, S, Yan, H, Yang, E, Yang, W, Ye, Y, Ye, Z, Yli-Kauhaluoma, J, Yoneyama, H, Yu, Y, Yuan, G, Yuh, C, Zaccolo, M, Zeng, C, Zevnik, B, Zhang, L, Zhang, Y, Zhao, Y, Zhou, M, Zuberbier, T, Aanei, C, Ahmad, R, Al-Lawama, M, Alanio, A, Allardyce, J, Alonso-Caneiro, D, Atack, J, Baier, D, Bansal, A, Benezeth, Y, Berbesque, C, Berrevoet, F, Biedermann, P, Bijleveld, E, Bittner, F, Blombach, F, van den Bos, W, Boudreau, S, Bramoweth, A, Braubach, O, Cai, Y, Campbell, M, Catry, T, Chen, X, Cheng, S, Chung, H, Chavez-Fumagalli, M, 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D., Blaskovich M. A. T., Blum R., Boelaert M., Bogdanos D., Bosch C., Bourgoin T., Bouvard D., Boykin L. M., Bradley G., Braun D., Brownlie J., Bruhl A., Burt A., Butler L. M., Byrareddy S. N., Byrne H. J., Cabantous S., Calatayud S., Candal E., Carlson K., Casillas S., Castelvetro V., Caswell P. T., Cavalli G., Cerovsky V., Chagoyen M., Chen C. -S., Chen D. F., Chen H., Chen J. -T., Chen Y., Cheng C., Cheng J., Chinapaw M., Chinopoulos C., Cho W. C. S., Chong L., Chowdhury D., Chwalibog A., Ciresi A., Cockcroft S., Conesa A., Cook P. A., Cooper D. N., Coqueret O., Corea E. M., Costa A., Costa E., Coupland C., Crawford S. Y., Cruz A. D., Cui H., Cui Q., Culver D. C., D'Angiulli A., Dahms T. E. S., Daigle F., Dalgleish R., Danielsen H. E., Darras S., Davidson S. M., Day D. A., Degirmenci V., Demaison L., Devriendt K., Ding J., Dogan Y., Dong X. C., Donner C. F., Dressick W., Drevon C. A., Duan H., Ducho C., Dumaz N., Dwarakanath B. S., Ebell M. 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A., van Meerten T., Min R., Moal I., Molari M., Molleman L., Mondal S. R., van de Mortel T., Moss W. N., Moultos O. A., Mukherjee M., Nakayama K., Narayan E., Neumann P. -A., Nie J., Nie Y., Niemeyer F., Nolan F., Nwaiwu O., Oldenmenger W. H., Olumayede E., Ou J., Pallebage-Gamarallage M., Pearce S. P., Pelkonen T., Pelleri M. C., Pereira J. L., Pheko M., Pinto K. A., Piovesan A., Pluess M., Podolsky I. M., Prescott J., Qi D., Qi X., Raikou V. D., Ranft A., Rhodes J., Rotge J. -Y., Rowe A. D., Saggar M., Schuon R. A., Shahid S., Shalchyan V., Shirvalkar P., Shiryayev O., Singh J., Smout M. J., Soares A., Song C., Srivastava K., Srivastava R. K., Sun J., Szabo A., Szymanski W., Tai C. N. P., Takeuchi H., Tanadini-Lang S., Tang F., Tao W., Theron G., Tian C. F., Tian Y. -S., Tuttle L. M., Valenti A., Verlot P., Walker M., Wang J., Welter D., Winslade M., Wu D., Wu Y. -R., Xiao H., Xu B., Xu Z., Yang D., Yang M., Yankilevich P., You Y., Yu C., Zhan J., Zhang G., Zhang K., Zhang T., Zhao G., Zhao J., Zhou X., Zhu Z., Ajani P. A., Anazodo U. C., Bagloee S. A., Bail K., Bar I., Bathelt J., Benkeser D., Bernier M. L., Blanchard A. M., Boakye D. W., Bonatsos V., Boon M. H., Bouboulis G., Bromfield E., Brown J., Bul K. C. M., Burton K. J., Butkowski E. G., Carroll G., Chao F., Charrier E. E., Chen Y. -C., Choi J. R., Christoffersen T., Comel J. C., Cosse C., Cui Y., van Dessel P., Diodato D., Duffey M., Dutt A., Egea L. G., El-Said M., Faye M., Fernandez-Fernandez B., Foley K. G., Founou L. L., Fu F., Gadelkareem R. A., Galimov E., Garip G., Gemmill A., Gouil Q., Grey J., Gridneva Z., Grothe M. J., Grebert T., Guerrero F., Guignard L., Haenssgen M. J., Hasler D., Holgate J. Y., Huang A., Hulse-Kemp A. M., Jean-Quartier C., Jeon S. -M., Jia Y., Jutzeler C., Kalatzis P., Karim M., Karsay K., Keitel A., Kempe A., Keown J. R., Khoo C. M., Khwaja N., Kievit R. A., Kosanic S., Koutoukidis D. A., Kramer P., Kumar D., Kirag N., Lanza G., Le T. D., Leem J. W., Leightley D., Leite A., Lercher L., Li Y., Lim R., Lima L. R. A., Lin L., Ling T., Liu Y., Liu Z., Lu Y., Lum F. M., Luo H., Machhi J., Macleod A., Macwan I., Madala H. R., Madani N., de Maio N., Makowiecki K., Mallinson D. J., Margelyte R., Maria C., Markonis Y., Marsili L., Mavoa S., McWilliams L., Megersa M., Souto-Maior C., Menichetti J., Mercieca-Bebber R., Miller J. J., Minde D. -P. M., Minges A., Mishra E., Mishra V. R., Moores C., Morrice N., Moskalensky A. E., Navarin N., Negera E., Nolet P., Nordberg A., Norden R., Nowicki J. P., Olova N., Olszewski P., Onzima R., Pan C. -L., Park C., Park D. I., Park S., Patil C. D., Pedro S. A., Perry S. R., Peter J., Peterson B. 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O., Bach-Mortensen A., Baltiansky L., Bartas M., Belachew K. Y., Bhardwaj V., Binder K., Bland N. S., Boah M., Bullen B., Calabro G. E., Callahan T. J., Cao B., Chalmers K., Chang W., Che Z., Chen A. T. Y., Chen Z., Choi Y., Chowdhury M. A. K., Christensen M. R., Cooke R. S. C., Cottini M., Covington N. V., Cunningham C., Delarocque J., Devos L., Dhar A. R., Ding K. -F., Dong K., Dong Z., Dreyer N., Ekstrand C., Fardet T., Feleke B. E., Feurer T., Freitas A., Gao T., Giganti F., Grabowski P., Guerra-Mora J. R., Guo C., Guo X., Gupta H., He S., Heijne M., Heinemann S., Hogrebe A., Huang Z., Iskander-Rizk S., Iyer L. M., Jahan Y., James A. S., Joel E., Joffroy B., Jegousse C., Kambondo G., Karnati P., Kaya C., Ke A., Kelly D., Kickert R., Kidibule P. E., Kieselmann J. P., Kim H. J., Kitazawa T., Lamberts A., Liang H., Linn S. N., Litfin T., Liusuo W., Lygirou V., Mahato A. K., Mai Z. -M., Major R. W., Mali S., Mallis P., Mao W., Marvin-Dowle K., Mason L. D., Merideth B., Merino-Plaza M. 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- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
- Published
- 2019
22. Characterisation of the British honey bee metagenome
- Author
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Regan, T, Barnett, MW, Laetsch, DR, Bush, SJ, Wragg, D, Budge, GE, Highet, F, Dainat, B, De Miranda, JR, Watson, M, Blaxter, M, and Freeman, TC
- Subjects
animal structures ,Microbiota ,Science ,fungi ,Genetic Variation ,food and beverages ,Sequence Analysis, DNA ,Bees ,complex mixtures ,Article ,United Kingdom ,Contig Mapping ,behavior and behavior mechanisms ,Animals ,Metagenome ,lcsh:Q ,Metagenomics ,Symbiosis ,lcsh:Science - Abstract
The European honey bee (Apis mellifera) plays a major role in pollination and food production. Honey bee health is a complex product of the environment, host genetics and associated microbes (commensal, opportunistic and pathogenic). Improved understanding of these factors will help manage modern challenges to bee health. Here we used DNA sequencing to characterise the genomes and metagenomes of 19 honey bee colonies from across Britain. Low heterozygosity was observed in many Scottish colonies which had high similarity to the native dark bee. Colonies exhibited high diversity in composition and relative abundance of individual microbiome taxa. Most non-bee sequences were derived from known honey bee commensal bacteria or pathogens. However, DNA was also detected from additional fungal, protozoan and metazoan species. To classify cobionts lacking genomic information, we developed a novel network analysis approach for clustering orphan DNA contigs. Our analyses shed light on microbial communities associated with honey bees and demonstrate the power of high-throughput, directed metagenomics for identifying novel biological threats in agroecosystems., Numerous microbial symbionts, both commensal and pathogenic, are associated with honey bees. Here, the authors genomically characterize this ‘metagenome’ of the British honey bee, identifying a diversity of commensal microbes as well as known and putative pathogens
- Published
- 2018
23. Building the city: urban transition and institutional frictions
- Author
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Venables, A, Henderson, J, and Regan, T
- Abstract
We model the building of a city, estimate parameters of the model, and calculate welfare losses from institutional frictions encountered in changing land-use. We distinguish formal and slum construction technologies; in contrast to slums, formal structures can be built tall, are durable, and non-malleable. As the city grows areas are initially developed informally, then formally, and then redeveloped periodically. Slums are modelled as a technology choice; however, institutional frictions in land markets may hinder their conversion to formal usage that requires secure property rights. Using unique data on Nairobi for 2003 and 2015, we develop a novel set of facts that support assumptions of the model, estimate all parameters of the model, and calculate welfare losses of conversion frictions. We track the dynamic evolution of the city and compare it with model predictions. In the core city formal sector, about 35% of buildings were torn down over 12 years and replaced by buildings on average three times higher. For slums in older areas near the centre, even after buying out slumlords, overcoming institutional frictions would yield gains amounting to $16,000 -18,000 per slum household, 30 times typical annual slum rent payments.
- Published
- 2020
24. Ramsar Wetlands of International Importance–Improving Conservation Outcomes
- Author
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Kingsford, R. T., primary, Bino, G., additional, Finlayson, C. M., additional, Falster, D., additional, Fitzsimons, J.A., additional, Gawlik, D. E., additional, Murray, N. J., additional, Grillas, P., additional, Gardner, R. C., additional, Regan, T. J., additional, Roux, D. J., additional, and Thomas, R. F., additional
- Published
- 2021
- Full Text
- View/download PDF
25. The effectiveness of interventions to increase preventive care provision for chronic disease risk behaviours in mental health settings: A systematic review and meta-analysis.
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Fehily, C, Hodder, R, Bartlem, K, Wiggers, J, Wolfenden, L, Dray, J, Bailey, J, Wilczynska, M, Stockings, E, Clinton-McHarg, T, Regan, T, Bowman, J, Fehily, C, Hodder, R, Bartlem, K, Wiggers, J, Wolfenden, L, Dray, J, Bailey, J, Wilczynska, M, Stockings, E, Clinton-McHarg, T, Regan, T, and Bowman, J
- Abstract
Clinical practice guidelines direct mental health services to provide preventive care to address client chronic disease risk behaviours, however, this care is not routinely provided. The aim of this systematic review was to synthesise evidence regarding the effectiveness of interventions to increase provision of preventive care by mental health services; by care element (ask, assess, advice, assist, arrange) and risk behaviour (tobacco smoking, poor nutrition, harmful alcohol consumption, physical inactivity). Electronic bibliographic databases, Google Scholar, relevant journals, and included study reference lists were searched. Eligible studies were of any design with a comparison group that reported the effectiveness of an intervention to increase the provision of at least one element of preventive care for at least one risk behaviour in a mental health setting. Twenty studies were included, most commonly examining smoking (n = 20) and 'ask' (n = 12). Meta-analysis found interventions involving task shifting were effective in increasing smoking 'advice' (n = 2 RCTs; p = 0.009) and physical activity 'advice' (n = 2 RCTs; p = 0.002). Overall, meta-analysis and narrative synthesis indicated that effective intervention strategies (categorised according to the Effective Practice and Organisation of Care taxonomy) were: task shifting, educational meetings, health information systems, local consensus processes, authority and accountability, and reminders. The most consistent findings across studies were with regard to preventive care for smoking, while conflicting or limited evidence was found regarding other risk behaviours. While further rigorous research examining key risk behaviours is recommended, the findings may inform the selection of strategies for future interventions and service delivery initiatives.
- Published
- 2020
26. Building the city: sunk capital, sequencing, and institutional frictions
- Author
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Henderson, J, Regan, T, and Venables, A
- Abstract
We model the building of a city, estimate parameters of the model, and calculate welfare losses from institutional frictions encountered in changing land-use. We distinguish formal and slum construction technologies; in contrast to slums, formal structures can be built tall, are durable, and non-malleable. As the city grows areas are initially developed informally, then formally, and then redeveloped periodically. Slums are modelled as a technology choice and do not depend on property rights per se; however institutional frictions may hinder their conversion to formal usage. Using unique data on Nairobi for 2003 and 2015 we develop a novel set of facts that support assumptions of the model and calculate welfare losses of conversion frictions. We track the dynamic evolution of the city, where in the core city about 35% of formal sector buildings were torn down over 12 years and replaced by buildings on average three times higher. For slums in older areas near the centre, even after buying out slumlords, formalization would yield gains amounting to over $17,000 per slum household, 30 times typical annual slum rent payments.
- Published
- 2019
27. Investigation of a requirement for the PsbP-like protein in Synechocystis sp. PCC 6803
- Author
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Summerfield, Tina C., Winter, Regan T., and Eaton-Rye, Julian J.
- Published
- 2005
- Full Text
- View/download PDF
28. Characteristics of 40-Gbit/s pulses generated using a lithium niobate modulator at 1550m using frequency resolved optical gating
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Thomsen, Benn C., Reid, Douglas A., Watts, Regan T., Barry, Liam P., and Harvey, John D.
- Subjects
Lithium niobate -- Analysis ,Lithium niobate -- Research ,Pulse modulation (Electronics) -- Analysis ,Pulse modulation (Electronics) -- Structure ,Optical communications -- Analysis ,Optical communications -- Structure - Published
- 2004
29. The upgraded DØ detector
- Author
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Abazov, V.M., Abbott, B., Abolins, M., Acharya, B.S., Adams, D.L., Adams, M., Adams, T., Agelou, M., Agram, J.-L., Ahmed, S.N., Ahn, S.H., Ahsan, M., Alexeev, G.D., Alkhazov, G., Alton, A., Alverson, G., Alves, G.A., Anastasoaie, M., Andeen, T., Anderson, J.T., Anderson, S., Andrieu, B., Angstadt, R., Anosov, V., Arnoud, Y., Arov, M., Askew, A., Åsman, B., Assis Jesus, A.C.S., Atramentov, O., Autermann, C., Avila, C., Babukhadia, L., Bacon, T.C., Badaud, F., Baden, A., Baffioni, S., Bagby, L., Baldin, B., Balm, P.W., Banerjee, P., Banerjee, S., Barberis, E., Bardon, O., Barg, W., Bargassa, P., Baringer, P., Barnes, C., Barreto, J., Bartlett, J.F., Bassler, U., Bhattacharjee, M., Baturitsky, M.A., Bauer, D., Bean, A., Baumbaugh, B., Beauceron, S., Begalli, M., Beaudette, F., Begel, M., Bellavance, A., Beri, S.B., Bernardi, G., Bernhard, R., Bertram, I., Besançon, M., Besson, A., Beuselinck, R., Beutel, D., Bezzubov, V.A., Bhat, P.C., Bhatnagar, V., Binder, M., Biscarat, C., Bishoff, A., Black, K.M., Blackler, I., Blazey, G., Blekman, F., Blessing, S., Bloch, D., Blumenschein, U., Bockenthien, E., Bodyagin, V., Boehnlein, A., Boeriu, O., Bolton, T.A., Bonamy, P., Bonifas, D., Borcherding, F., Borissov, G., Bos, K., Bose, T., Boswell, C., Bowden, M., Brandt, A., Briskin, G., Brock, R., Brooijmans, G., Bross, A., Buchanan, N.J., Buchholz, D., Buehler, M., Buescher, V., Burdin, S., Burke, S., Burnett, T.H., Busato, E., Buszello, C.P., Butler, D., Butler, J.M., Cammin, J., Caron, S., Bystricky, J., Canal, L., Canelli, F., Carvalho, W., Casey, B.C.K., Casey, D., Cason, N.M., Castilla-Valdez, H., Chakrabarti, S., Chakraborty, D., Chan, K.M., Chandra, A., Chapin, D., Charles, F., Cheu, E., Chevalier, L., Chi, E., Chiche, R., Cho, D.K., Choate, R., Choi, S., Choudhary, B., Chopra, S., Christenson, J.H., Christiansen, T., Christofek, L., Churin, I., Cisko, G., Claes, D., Clark, A.R., Clément, B., Clément, C., Coadou, Y., Colling, D.J., Coney, L., Connolly, B., Cooke, M., Cooper, W.E., Coppage, D., Corcoran, M., Coss, J., Cothenet, A., Cousinou, M.-C., Cox, B., Crépé-Renaudin, S., Cristetiu, M., Cummings, M.A.C., Cutts, D., da Motta, H., Das, M., Davies, B., Davies, G., Davis, G.A., Davis, W., De, K., de Jong, P., de Jong, S.J., De La Cruz-Burelo, E., De La Taille, C., De Oliveira Martins, C., Dean, S., Degenhardt, J.D., Déliot, F., Delsart, P.A., Del Signore, K., DeMaat, R., Demarteau, M., Demina, R., Demine, P., Denisov, D., Denisov, S.P., Desai, S., Diehl, H.T., Diesburg, M., Doets, M., Doidge, M., Dong, H., Doulas, S., Dudko, L.V., Duflot, L., Dugad, S.R., Duperrin, A., Dvornikov, O., Dyer, J., Dyshkant, A., Eads, M., Edmunds, D., Edwards, T., Ellison, J., Elmsheuser, J., Eltzroth, J.T., Elvira, V.D., Eno, S., Ermolov, P., Eroshin, O.V., Estrada, J., Evans, D., Evans, H., Evdokimov, A., Evdokimov, V.N., Fagan, J., Fast, J., Fatakia, S.N., Fein, D., Feligioni, L., Ferapontov, A.V., Ferbel, T., Ferreira, M.J., Fiedler, F., Filthaut, F., Fisher, W., Fisk, H.E., Fleck, I., Fitzpatrick, T., Flattum, E., Fleuret, F., Flores, R., Foglesong, J., Fortner, M., Fox, H., Franklin, C., Freeman, W., Fu, S., Fuess, S., Gadfort, T., Galea, C.F., Gallas, E., Galyaev, E., Gao, M., Garcia, C., Garcia-Bellido, A., Gardner, J., Gavrilov, V., Gay, A., Gay, P., Gelé, D., Gelhaus, R., Genser, K., Gerber, C.E., Gershtein, Y., Gillberg, D., Geurkov, G., Ginther, G., Gobbi, B., Goldmann, K., Golling, T., Gollub, N., Golovtsov, V., Gómez, B., Gomez, G., Gomez, R., Goodwin, R., Gornushkin, Y., Gounder, K., Goussiou, A., Graham, D., Graham, G., Grannis, P.D., Gray, K., Greder, S., Green, D.R., Green, J., Green, J.A., Greenlee, H., Greenwood, Z.D., Gregores, E.M., Grinstein, S., Gris, Ph., Grivaz, J.-F., Groer, L., Grünendahl, S., Grünewald, M.W., Gu, W., Guglielmo, J., Gupta, A., Gurzhiev, S.N., Gutierrez, G., Gutierrez, P., Haas, A., Hadley, N.J., Haggard, E., Haggerty, H., Hagopian, S., Hall, I., Hall, R.E., Han, C., Han, L., Hance, R., Hanagaki, K., Hanlet, P., Hansen, S., Harder, K., Harel, A., Harrington, R., Hauptman, J.M., Hauser, R., Hays, C., Hays, J., Hazen, E., Hebbeker, T., Hebert, C., Hedin, D., Heinmiller, J.M., Heinson, A.P., Heintz, U., Hensel, C., Hesketh, G., Hildreth, M.D., Hirosky, R., Hobbs, J.D., Hoeneisen, B., Hohlfeld, M., Hong, S.J., Hooper, R., Hou, S., Houben, P., Hu, Y., Huang, J., Huang, Y., Hynek, V., Huffman, D., Iashvili, I., Illingworth, R., Ito, A.S., Jabeen, S., Jacquier, Y., Jaffré, M., Jain, S., Jain, V., Jakobs, K., Jayanti, R., Jenkins, A., Jesik, R., Jiang, Y., Johns, K., Johnson, M., Johnson, P., Jonckheere, A., Jonsson, P., Jöstlein, H., Jouravlev, N., Juarez, M., Juste, A., Kaan, A.P., Kado, M.M., Käfer, D., Kahl, W., Kahn, S., Kajfasz, E., Kalinin, A.M., Kalk, J., Kalmani, S.D., Karmanov, D., Kasper, J., Katsanos, I., Kau, D., Kaur, R., Ke, Z., Kehoe, R., Kermiche, S., Kesisoglou, S., Khanov, A., Kharchilava, A., Kharzheev, Y.M., Kim, H., Kim, K.H., Kim, T.J., Kirsch, N., Klima, B., Klute, M., Kohli, J.M., Konrath, J.-P., Komissarov, E.V., Kopal, M., Korablev, V.M., Kostritski, A., Kotcher, J., Kothari, B., Kotwal, A.V., Koubarovsky, A., Kozelov, A.V., Kozminski, J., Kryemadhi, A., Kouznetsov, O., Krane, J., Kravchuk, N., Krempetz, K., Krider, J., Krishnaswamy, M.R., Krzywdzinski, S., Kubantsev, M., Kubinski, R., Kuchinsky, N., Kuleshov, S., Kulik, Y., Kumar, A., Kunori, S., Kupco, A., Kurča, T., Kvita, J., Kuznetsov, V.E., Kwarciany, R., Lager, S., Lahrichi, N., Landsberg, G., Larwill, M., Laurens, P., Lavigne, B., Lazoflores, J., Le Bihan, A.-C., Le Meur, G., Lebrun, P., Lee, S.W., Lee, W.M., Leflat, A., Leggett, C., Lehner, F., Leitner, R., Leonidopoulos, C., Leveque, J., Lewis, P., Li, J., Li, Q.Z., Li, X., Lima, J.G.R., Lincoln, D., Lindenmeyer, C., Linn, S.L., Linnemann, J., Lipaev, V.V., Lipton, R., Litmaath, M., Lizarazo, J., Lobo, L., Lobodenko, A., Lokajicek, M., Lounis, A., Love, P., Lu, J., Lubatti, H.J., Lucotte, A., Lueking, L., Luo, C., Lynker, M., Lyon, A.L., Machado, E., Maciel, A.K.A., Madaras, R.J., Mättig, P., Magass, C., Magerkurth, A., Magnan, A.-M., Maity, M., Makovec, N., Mal, P.K., Malbouisson, H.B., Malik, S., Malyshev, V.L., Manakov, V., Mao, H.S., Maravin, Y., Markley, D., Markus, M., Marshall, T., Martens, M., Martin, M., Martin-Chassard, G., Mattingly, S.E.K., Matulik, M., Mayorov, A.A., McCarthy, R., McCroskey, R., McKenna, M., McMahon, T., Meder, D., Melanson, H.L., Melnitchouk, A., Mendes, A., Mendoza, D., Mendoza, L., Meng, X., Merekov, Y.P., Merkin, M., Merritt, K.W., Meyer, A., Meyer, J., Michaut, M., Miao, C., Miettinen, H., Mihalcea, D., Mikhailov, V., Miller, D., Mitrevski, J., Mokhov, N., Molina, J., Mondal, N.K., Montgomery, H.E., Moore, R.W., Moulik, T., Muanza, G.S., Mostafa, M., Moua, S., Mulders, M., Mundim, L., Mutaf, Y.D., Nagaraj, P., Nagy, E., Naimuddin, M., Nang, F., Narain, M., Narasimhan, V.S., Narayanan, A., Naumann, N.A., Neal, H.A., Negret, J.P., Nelson, S., Neuenschwander, R.T., Neustroev, P., Noeding, C., Nomerotski, A., Novaes, S.F., Nozdrin, A., Nunnemann, T., Nurczyk, A., Nurse, E., O’Dell, V., O’Neil, D.C., Oguri, V., Olis, D., Oliveira, N., Olivier, B., Olsen, J., Oshima, N., Oshinowo, B.O., Otero y Garzón, G.J., Padley, P., Papageorgiou, K., Parashar, N., Park, J., Park, S.K., Parsons, J., Partridge, R., Parua, N., Patwa, A., Pawloski, G., Perea, P.M., Perez, E., Peters, O., Pétroff, P., Petteni, M., Phaf, L., Piegaia, R., Pleier, M.-A., Podesta-Lerma, P.L.M., Podstavkov, V.M., Pogorelov, Y., Pol, M.-E., Pompoš, A., Polosov, P., Pope, B.G., Popkov, E., Porokhovoy, S., Prado da Silva, W.L., Pritchard, W., Prokhorov, I., Prosper, H.B., Protopopescu, S., Przybycien, M.B., Qian, J., Quadt, A., Quinn, B., Ramberg, E., Ramirez-Gomez, R., Rani, K.J., Ranjan, K., Rao, M.V.S., Rapidis, P.A., Rapisarda, S., Raskowski, J., Ratoff, P.N., Ray, R.E., Reay, N.W., Rechenmacher, R., Reddy, L.V., Regan, T., Renardy, J.-F., Reucroft, S., Rha, J., Ridel, M., Rijssenbeek, M., Ripp-Baudot, I., Rizatdinova, F., Robinson, S., Rodrigues, R.F., Roco, M., Rotolo, C., Royon, C., Rubinov, P., Ruchti, R., Rucinski, R., Rud, V.I., Russakovich, N., Russo, P., Sabirov, B., Sajot, G., Sánchez-Hernández, A., Sanders, M.P., Santoro, A., Satyanarayana, B., Savage, G., Sawyer, L., Scanlon, T., Schaile, D., Schamberger, R.D., Scheglov, Y., Schellman, H., Schieferdecker, P., Schmitt, C., Schwanenberger, C., Schukin, A.A., Schwartzman, A., Schwienhorst, R., Sengupta, S., Severini, H., Shabalina, E., Shamim, M., Shankar, H.C., Shary, V., Shchukin, A.A., Sheahan, P., Shephard, W.D., Shivpuri, R.K., Shishkin, A.A., Shpakov, D., Shupe, M., Sidwell, R.A., Simak, V., Sirotenko, V., Skow, D., Skubic, P., Slattery, P., Smith, D.E., Smith, R.P., Smolek, K., Snow, G.R., Snow, J., Snyder, S., Söldner-Rembold, S., Song, X., Song, Y., Sonnenschein, L., Sopczak, A., Sorín, V., Sosebee, M., Soustruznik, K., Souza, M., Spartana, N., Spurlock, B., Stanton, N.R., Stark, J., Steele, J., Stefanik, A., Steinberg, J., Steinbrück, G., Stevenson, K., Stolin, V., Stone, A., Stoyanova, D.A., Strandberg, J., Strang, M.A., Strauss, M., Ströhmer, R., Strom, D., Strovink, M., Stutte, L., Sumowidagdo, S., Sznajder, A., Talby, M., Tentindo-Repond, S., Tamburello, P., Taylor, W., Telford, P., Temple, J., Terentyev, N., Teterin, V., Thomas, E., Thompson, J., Thooris, B., Titov, M., Toback, D., Tokmenin, V.V., Tolian, C., Tomoto, M., Tompkins, D., Toole, T., Torborg, J., Touze, F., Towers, S., Trefzger, T., Trincaz-Duvoid, S., Trippe, T.G., Tsybychev, D., Tuchming, B., Tully, C., Turcot, A.S., Tuts, P.M., Utes, M., Uvarov, L., Uvarov, S., Uzunyan, S., Vachon, B., van den Berg, P.J., van Gemmeren, P., Van Kooten, R., van Leeuwen, W.M., Varelas, N., Varnes, E.W., Vartapetian, A., Vasilyev, I.A., Vaupel, M., Vaz, M., Verdier, P., Vertogradov, L.S., Verzocchi, M., Vigneault, M., Villeneuve-Seguier, F., Vishwanath, P.R., Vlimant, J.-R., Von Toerne, E., Vorobyov, A., Vreeswijk, M., Vu Anh, T., Vysotsky, V., Wahl, H.D., Walker, R., Wallace, N., Wang, L., Wang, Z.-M., Warchol, J., Warsinsky, M., Watts, G., Wayne, M., Weber, M., Weerts, H., Wegner, M., Wermes, N., Wetstein, M., White, A., White, V., Whiteson, D., Wicke, D., Wijnen, T., Wijngaarden, D.A., Wilcer, N., Willutzki, H., Wilson, G.W., Wimpenny, S.J., Wittlin, J., Wlodek, T., Wobisch, M., Womersley, J., Wood, D.R., Wyatt, T.R., Wu, Z., Xie, Y., Xu, Q., Xuan, N., Yacoob, S., Yamada, R., Yan, M., Yarema, R., Yasuda, T., Yatsunenko, Y.A., Yen, Y., Yip, K., Yoo, H.D., Yoffe, F., Youn, S.W., Yu, J., Yurkewicz, A., Zabi, A., Zanabria, M., Zatserklyaniy, A., Zdrazil, M., Zeitnitz, C., Zhang, B., Zhang, D., Zhang, X., Zhao, T., Zhao, Z., Zheng, H., Zhou, B., Zhu, J., Zielinski, M., Zieminska, D., Zieminski, A., Zitoun, R., Zmuda, T., Zutshi, V., Zviagintsev, S., Zverev, E.G., and Zylberstejn, A.
- Published
- 2006
- Full Text
- View/download PDF
30. Fractures in water mains : the effect of longitudinal bending
- Author
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Regan, T.
- Subjects
624 ,Civil engineering - Published
- 1982
31. The muon system of the Run II DØ detector
- Author
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Abazov, V.M., Acharya, B.S., Alexeev, G.D., Alkhazov, G., Anosov, V.A., Baldin, B., Banerjee, S., Bardon, O., Bartlett, J.F., Baturitsky, M.A., Beutel, D., Bezzubov, V.A., Bodyagin, V., Butler, J.M., Cease, H., Chi, E., Denisov, D., Denisov, S.P., Diehl, H.T., Doulas, S., Dugad, S.R., Dvornikov, O.V., Dyshkant, A., Eads, M., Evdokimov, A., Evdokimov, V.N., Fitzpatrick, T., Fortner, M., Gavrilov, V., Gershtein, Y., Golovtsov, V., Gómez, B., Goodwin, R., Gornushkin, Yu.A., Green, D.R., Gupta, A., Gurzhiev, S.N., Gutierrez, G., Haggerty, H., Hanlet, P., Hansen, S., Hazen, E., Hedin, D., Hoeneisen, B., Ito, A.S., Jayanti, R., Johns, K., Jouravlev, N., Kalinin, A.M., Kalmani, S.D., Kharzheev, Y.N., Kirsch, N., Komissarov, E.V., Korablev, V.M., Kostritsky, A., Kozelov, A.V., Kozlovsky, M., Kravchuk, N.P., Krishnaswamy, M.R., Kuchinsky, N.A., Kuleshov, S., Kupco, A., Larwill, M., Leitner, R., Lipaev, V.V., Lobodenko, A., Lokajicek, M., Lubatti, H.J., Machado, E., Maity, M., Malyshev, V.L., Mao, H.S., Marcus, M., Marshall, T., Mayorov, A.A., McCroskey, R., Merekov, Y.P., Mikhailov, V.A., Mokhov, N., Mondal, N.K., Nagaraj, P., Narasimham, V.S., Narayanan, A., Negret, J.P., Neustroev, P., Nozdrin, A.A., Oshinowo, B., Parashar, N., Parua, N., Podstavkov, V.M., Polozov, P., Porokhovoi, S.Y., Prokhorov, I.K., Rao, M.V.S., Raskowski, J., Reddy, L.V., Regan, T., Rotolo, C., Russakovich, N.A., Sabirov, B.M., Satyanarayana, B., Scheglov, Y., Schukin, A.A., Shankar, H.C., Shishkin, A.A., Shpakov, D., Shupe, M., Simak, V., Sirotenko, V., Smith, G., Smolek, K., Soustruznik, K., Stefanik, A., Steinberg, J., Stolin, V., Stoyanova, D.A., Stutte, L., Temple, J., Terentyev, N., Teterin, V.V., Tokmenin, V.V., Tompkins, D., Uvarov, L., Uvarov, S., Vasilyev, I.A., Vertogradov, L.S., Vishwanath, P.R., Vorobyov, A., Vysotsky, V.B., Willutzki, H., Wobisch, M., Wood, D.R., Yamada, R., Yatsunenko, Y.A., Yoffe, F., Zanabria, M., Zhao, T., Zieminska, D., Zieminski, A., and Zvyagintsev, S.A.
- Published
- 2005
- Full Text
- View/download PDF
32. An improved system for the targeted mutagenesis of the gene in sp. PCC 6803: mutation of D1-Glu244 to His impairs electron transfer between Q and Q of Photosystem II
- Author
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Forsman, Jack A., Winter, Regan T., and Eaton-Rye, Julian J.
- Subjects
0106 biological sciences ,Mutation ,Strain (chemistry) ,Photosystem II ,Chemistry ,Mutant ,Mutagenesis (molecular biology technique) ,Chromosome ,Plant Science ,medicine.disease_cause ,010603 evolutionary biology ,01 natural sciences ,Molecular biology ,Botany ,medicine ,Gene ,Ecology, Evolution, Behavior and Systematics ,Selectable marker ,010606 plant biology & botany - Abstract
The cyanobacterium Synechocystis sp. PCC 6803 has three copies of the psbA gene encoding the D1 reaction centre protein of Photosystem II (PS II). We have designed a mutagenesis system that allows introduction of mutations into the constitutively expressed psbA2 copy without affecting the expression of any flanking genes. A triple deletion strain was constructed in which psbA1 and psbA3 were removed by markerless deletions and psbA2 was replaced by a chloramphenicol-resistance cassette. A vector was then designed to enable the reintroduction of psbA2 in the chromosome using a kanamycin-resistance cassette as a selectable marker. This system was used to generate a control strain, which had an unmodified copy of psbA2, and two mutant strains which contained a copy of psbA2 where the codon for D1-Glu244 had been mutated to code for a His or Asp. The D1-Glu244 residue was targeted as it has been hypothesised to participate in a hydrogen-bond network that is required for protonation of the PS II second...
- Published
- 2019
- Full Text
- View/download PDF
33. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
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Brown, P. Zhou, Y. Tan, A.-C. El-Esawi, M.A. Liehr, T. Blanck, O. Gladue, D.P. Almeida, G.M.F. Cernava, T. Sorzano, C.O. Yeung, A.W.K. Engel, M.S. Chandrasekaran, A.R. Muth, T. Staege, M.S. Daulatabad, S.V. Widera, D. Zhang, J. Meule, A. Honjo, K. Pourret, O. Yin, C.-C. Zhang, Z. Cascella, M. Flegel, W.A. Goodyear, C.S. van Raaij, M.J. Bukowy-Bieryllo, Z. Campana, L.G. Kurniawan, N.A. Lalaouna, D. Hüttner, F.J. Ammerman, B.A. Ehret, F. Cobine, P.A. Tan, E.-C. Han, H. Xia, W. McCrum, C. Dings, R.P.M. Marinello, F. Nilsson, H. Nixon, B. Voskarides, K. Yang, L. Costa, V.D. Bengtsson-Palme, J. Bradshaw, W. Grimm, D.G. Kumar, N. Martis, E. Prieto, D. Sabnis, S.C. Amer, S.E.D.R. Liew, A.W.C. Perco, P. Rahimi, F. Riva, G. Zhang, C. Devkota, H.P. Ogami, K. Basharat, Z. Fierz, W. Siebers, R. Tan, K.H. Boehme, K.A. Brenneisen, P. Brown, J.A.L. Dalrymple, B.P. Harvey, D.J. Ng, G. Werten, S. Bleackley, M. Dai, Z. Dhariwal, R. Gelfer, Y. Hartmann, M.D. Miotla, P. Tamaian, R. Govender, P. 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Webster, R. Wei, J. Wibowo, D. Wingenbach, T.S.H. Xavier, R.M. Xiao, S. Xiong, P. Xu, S. Xu, S. Yao, R. Yao, W. Yin, Q. Yu, Y. Zaitsu, M. Zeineb, Z. Zhan, X.-Y. Zhang, J. Zhang, R. Zhang, W. Zhang, X. Zheng, S. Zhou, B. Zhou, X. Ahmad, H. Akinwumi, S.A. Albery, G.F. Alhowimel, A. Ali, J. Alshehri, M. Alsuhaibani, M. Anikin, A. Azubuike, S.O. Bach-Mortensen, A. Baltiansky, L. Bartas, M. Belachew, K.Y. Bhardwaj, V. Binder, K. Bland, N.S. Boah, M. Bullen, B. Calabrò, G.E. Callahan, T.J. Cao, B. Chalmers, K. Chang, W. Che, Z. Chen, A.T.Y. Chen, H. Chen, H. Chen, Y. Chen, Z. Choi, Y. Chowdhury, M.A.K. Christensen, M.R. Cooke, R.S.C. Cottini, M. Covington, N.V. Cunningham, C. Delarocque, J. Devos, L. Dhar, A.R. Ding, K.-F. Dong, K. Dong, Z. Dreyer, N. Ekstrand, C. Fardet, T. Feleke, B.E. Feurer, T. Freitas, A. Gao, T. Gebremedhin Giganti, F. Grabowski, P. Guerra-Mora, J.R. Guo, C. Guo, X. Gupta, H. He, S. Heijne, M. Heinemann, S. Hogrebe, A. Huang, Z. Iskander-Rizk, S. Iyer, L.M. Jahan, Y. James, A.S. Joel, E. Joffroy, B. Jégousse, C. Kambondo, G. Karnati, P. Kaya, C. Ke, A. Kelly, D. Kickert, R. Kidibule, P.E. Kieselmann, J.P. Kim, H.J. Kitazawa, T. Lamberts, A. Li, Y. Liang, H. Linn, S.N. Litfin, T. Liusuo, W. Lygirou, V. Mahato, A.K. Mai, Z.-M. Major, R.W. Mali, S. Mallis, P. Mao, W. Marvin-Dowle, K. Mason, L.D. Merideth, B. Merino-Plaza, M.J. Merlaen, B. Messina, R. Mishra, A.K. Muhammad, J. Musinguzi, C. Nanou, A. Naqash, A. Nguyen, J.T. Nguyen, T.T.H. Ni, D. Nida Notcovich, S. Ohst, B. Ollivier, Q.R. Osses, D.F. Peng, X. Plantinga, A. Pulia, M. Rafiq, M. Raman, A. Raucher-Chéné Rawski, R. Ray, A. Razak, L.A. Rudolf, K. Rusch, P. Sadoine, M.L. Schmidt, A. Schurr, R. Searles, S. Sharma, S. Sheehan, B. Shi, C. Shohayeb, B. Sommerlad, A. Strehlow, J. Sun, X. Sundar, R. Taherzadeh, G. Tahir, N.D.M. Tang, J. Testa, J. Tian, Z. Tingting, Q. Verheijen, G.P. Vickstrom, C. Wang, T. Wang, X. Wang, Z. Wei, P. Wilson, A. Wyart Yassine, A.-A. Yousefzadeh, A. Zare, A. Zeng, Z. Zhang, C. Zhang, H. Zhang, L. Zhang, T. Zhang, W. Zhang, Z. Zhou, J. Zhu, D. Adamo, V. Adeyemo, A.A. Aggelidou, M. Al-Owaifeer, A.M. Al-Riyami, A.Z. Alzghari, S.K. Andersen, V. Angus, K. Asaduzzaman, M. Asady, H. Ato, D. Bai, X. Baines, R.L. Ballantyne, M. Ban, B. Beck, J. Ben-Nafa, W. Black, E. Blancher, A. Blankstein, R. Bodagh, N. Borges, P. Brooks, A. Brox-Ponce, J. Brunetti, A. Canham, C.D. Carninci, P. Carvajal, R. Chang, S.C. Chao, J. Chatterjee, P. Chen, H. Chen, L. Chen, Y.-C. Chhatriwalla, A.K. Chikowe, I. Chuang, T.-J. Collevatti, R.G. Cornejo, D.A.V. Cuenda, A. Dao, M. Dauga, D. Deng, Z. Devkota, K. Doan, L.V. Elewa, Y.H.A. Fan, D. Faruk, M. Feifei, S. Ferguson, T.S. Fleres, F. Foster, E.J. Foster, S. Furer, T. Gao, Y. Garcia-Rivera, E.J. Gazdar, A. George, R.B. Ghosh, S. Gianchecchi, E. Gleason, J.M. Hackshaw, A. Hall, A. Hall, R. Harper, P. Hogg, W.E. Huang, G. Hunter, K.E. Ijzerman, A.P. Jesus, C. Jian, G. Lewis, J.S., Jr. Kanj, S.S. Kaur, H. Kelly, S. Kheir, F. Kichatova, V.S. Kiyani, M. Klein, R. Kovesi, T. Kraschnewski, J.L. Kumar, A.P. Labutin, D. Lazo-Langner, A. Leclercq, G. Li, M. Li, Q. Li, T. Li, Y. Liao, W.-T. Liao, Z.-Y. Lin, J. Lizer, J. Lobreglio, G. Lowies, C. Lu, C. Majeed, H. Martin, A. Martinez-Sobrido, L. Meresh, E. Middelveen, M. Mohebbi, A. Mota, J. Mozaheb, Z. Muyaya, L. Nandhakumar, A. Ng, S.H.X. Obeidat, M. Oh, D.-H. Owais, M. Pace-Asciak, P. Panwar, A. Park, C. Patterson, C. Penagos-Tabaree, F. Pianosi, P.T. Pinzi, V. Pridans, C. Psaroulaki, A. Pujala, R.K. Pulido-Arjona, L. Qi, P.-F. Rahman, P. Rai, N.K. Rassaf, T. Refardt, J. Ricciardi, W. Riess, O. Rovas, A. Sacks, F.M. Saleh, S. Sampson, C. Schmutz, A. Sepanski, R. Sharma, N. Singh, M. Spearman, P. Subramaniapillai, M. Swali, R. Tan, C.M. Tellechea, J.I. Thomas, L.-M. Tong, X. Vavvas, D.G. Veys, R. Vitriol, V. Wang, H.-D. Wang, J. Wang, J. Waugh, J. Webb, S.A. Williams, B.A. Workman, A.D. Xiang, T. Xie, L.-X. Xu, J. Xu, T. Yang, C. Yoon, J.G. Yuan, C.M. Zaritsky, A. Zhang, Y. Zhao, H. Zuckerman, H. Lyu, R. Pullan, W. RELISH Consortium
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science. © The Author(s) 2019. Published by Oxford University Press.
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- 2019
34. An improved system for the targeted mutagenesis of the psbA2 gene in Synechocystis sp. PCC 6803: mutation of D1-Glu244 to His impairs electron transfer between QA and QB of Photosystem II
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Forsman, Jack A., Winter, Regan T., and Eaton-Rye, Julian J.
- Abstract
The cyanobacterium Synechocystis sp. PCC 6803 has three copies of the psbA gene encoding the D1 reaction centre protein of Photosystem II (PS II). We have designed a mutagenesis system that allows introduction of mutations into the constitutively expressed psbA2 copy without affecting the expression of any flanking genes. A triple deletion strain was constructed in which psbA1 and psbA3 were removed by markerless deletions and psbA2 was replaced by a chloramphenicol-resistance cassette. A vector was then designed to enable the reintroduction of psbA2 in the chromosome using a kanamycin-resistance cassette as a selectable marker. This system was used to generate a control strain, which had an unmodified copy of psbA2, and two mutant strains which contained a copy of psbA2 where the codon for D1-Glu244 had been mutated to code for a His or Asp. The D1-Glu244 residue was targeted as it has been hypothesised to participate in a hydrogen-bond network that is required for protonation of the PS II secondary plastoquinone electron acceptor QB. While the phenotype of the control strain was similar to wild type, the E244H mutant exhibited impaired oxygen evolution and altered electron transfer between the primary quinone acceptor QA and QB. However, substitution of Glu-244 by Asp resulted in a mutant more closely resembling the control strain.
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- 2019
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35. Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus
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Pridans, C, Raper, A, Davis, G, Alves, J, Sauter, K, Lefevre, L, Regan, T, Meek, S, Sutherland, L, Thomson, A, Clohisey, S, Bush, S, Rojo, R, Lisowski, Z, Wallace, R, Grabert, K, Upton, K, Tsai, Y, Brown, D, Smith, L, Summers, K, Mabbott, N, Piccardo, P, Cheeseman, M, Burdon, T, and Hume, D
- Subjects
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor ,Macrophages ,Organogenesis ,Models, Animal ,Mutation ,Immune System Development ,Animals ,Microglia ,Corrections ,Rats - Abstract
We have produced Csf1r-deficient rats by homologous recombination in embryonic stem cells. Consistent with the role of Csf1r in macrophage differentiation, there was a loss of peripheral blood monocytes, microglia in the brain, epidermal Langerhans cells, splenic marginal zone macrophages, bone-associated macrophages and osteoclasts, and peritoneal macrophages. Macrophages of splenic red pulp, liver, lung, and gut were less affected. The pleiotropic impacts of the loss of macrophages on development of multiple organ systems in rats were distinct from those reported in mice. Csf1r2/2 rats survived well into adulthood with postnatal growth retardation, distinct skeletal and bone marrow abnormalities, infertility, and loss of visceral adipose tissue. Gene expression analysis in spleen revealed selective loss of transcripts associated with the marginal zone and, in brain regions, the loss of known and candidate novel microglia-associated transcripts. Despite the complete absence of microglia, there was little overt phenotype in brain, aside from reduced myelination and increased expression of dopamine receptor-associated transcripts in striatum. The results highlight the redundant and nonredundant functions of CSF1R signaling and of macrophages in development,organogenesis, and homeostasis.
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- 2018
36. Left Ventricular Diastolic Dysfunction in Diabetic or Hypertensive Subjects: Role of Collagen Alterations
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Regan, T. J., primary, Jyothirmayi, G. N., additional, Laham, C., additional, and Jain, A., additional
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- 2001
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37. A Study of Enzyme-Ligand Binding of Chymotrypsin with Amino Acid Derivatives Using Infrared Spectroscopy
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Regan, T. E., Wharton, C. W., Merlin, Jean Claude, editor, Turrell, Sylvia, editor, and Huvenne, Jean Pierre, editor
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- 1995
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38. Thermally Induced Denaturation of Chymotrypsin Complexes Followed by Fourier Transform Infrared Spectroscopy
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Johal, S. S., Blackler, M., Regan, T., Wharton, C. W., Merlin, Jean Claude, editor, Turrell, Sylvia, editor, and Huvenne, Jean Pierre, editor
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- 1995
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39. LED pulser system for Fermilab's DØ Muon Scintillation counters
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Hanlet, P., Doulas, S., Kirsch, N., Marcus, M., Wood, D.R., Haggerty, H., Hansen, S., Ito, A.S., Jones, R., Regan, T., Acharya, B.S., Dugad, S., Satyanarayana, B., Pablo Negret, J., and Zanabria, M.
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- 2004
- Full Text
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40. Outpatient interventions for smoking cessation and reduction for adults with a mental disorder
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Stockings, E., Black, N., Bartlem, K.M., Metse, A.P., Regan, T., Bailey, J.M., Wolfenden, L., Wiggers, J., Bowman, J.A., Stockings, E., Black, N., Bartlem, K.M., Metse, A.P., Regan, T., Bailey, J.M., Wolfenden, L., Wiggers, J., and Bowman, J.A.
- Abstract
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary objective of this review is to determine the effectiveness of smoking reduction and cessation interventions (alone, or in combination with other interventions), delivered primarily in an outpatient or community‐based setting among individuals with mental disorders, on rates of abstinence at the longest follow‐up (minimum six months), mental health symptoms and adverse events. Secondary objectives are to examine the impact of such interventions on rates of abstinence at the end of the intervention, change in daily cigarette consumption, and quality‐of‐life or other function scores. We will explore (via subgroup analyses) potential differential effects on the basis of intervention type, control group type, recruitment setting (inpatient versus outpatient), mental disorder type, and motivation to quit at study intake. We may come across studies testing interventions which aim to increase the uptake of smoking interventions in people with a mental disorder. This may comprise interventions that either are incorporated into the system of delivering care, aimed at health professionals (e.g. within a community mental health facility), as well as interventions aimed directly at people with a mental disorder to increase uptake. In this case we aim to examine whether these interventions increase the uptake of the smoking cessation treatment among people with a mental disorder, as well as whether they ultimately result in increased quit rates.
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- 2019
41. Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: Protocol for a systematic review and meta-analysis
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Metse, A.P., Stockings, E., Bailey, J., Regan, T., Bartlem, K., Wolfenden, L., Taylor, G., Wiggers, J., Bowman, J., Metse, A.P., Stockings, E., Bailey, J., Regan, T., Bartlem, K., Wolfenden, L., Taylor, G., Wiggers, J., and Bowman, J.
- Abstract
Introduction Smoking among persons with a mental health disorder is associated with inequitable health, social and economic burden. Randomised controlled trials (RCTs) are considered the gold standard design for the assessment of healthcare intervention efficacy/effectiveness. However, many RCTs of smoking interventions for persons with a mental health disorder lack rigour due to low participant retention. No systematic review has pooled retention rates in randomised trials of smoking interventions for persons with a mental health disorder or explored associated factors. The aims of the systematic review will therefore be to: (1) summarise overall rates of participant retention in smoking cessation and reduction trials involving persons with a mental health disorder (including for experimental and control groups separately) and (2) determine if retention rates vary according to participant, environmental, researcher and study factors. Methods and analysis PsycINFO, EMBASE, MEDLINE, CENTRAL and The Cochrane Tobacco Addiction Review Group Specialised Register will be searched for reports of RCTs of outpatient smoking cessation or reduction interventions for adults with a mental health disorder. The search terms will include MeSH terms and free text words, and there will be no language or date restrictions. All databases will be searched from inception to present. Data will be analysed using the Mantel-Haenszel fixed-effect model, and where substantial heterogeneity (I2 >50%) is detected, DerSimonian & Laird inverse-variance random effects model. Pooled estimates and 95% CIs will be calculated for overall participant retention rates and for intervention and control trial arms separately. Associations between participant retention and participant, environmental, researcher and study factors will be assessed via subgroup analyses and, where sufficient data are obtained, meta-regression. Ethics and dissemination This study does not require ethical approval. The findings o
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- 2019
42. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
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Brown, P., Zhou, Y., Tan, A. -C., El-Esawi, M. A., Liehr, T., Blanck, O., Gladue, D. P., Almeida, G. M. F., Cernava, T., Sorzano, C. O., Yeung, A. W. K., Engel, M. S., Chandrasekaran, A. R., Muth, T., Staege, M. S., Daulatabad, S. V., Widera, D., Zhang, J., Meule, A., Honjo, K., Pourret, O., Yin, C. -C., Zhang, Z., Cascella, M., Flegel, W. A., Goodyear, C. S., van Raaij, M. J., Bukowy-Bieryllo, Z., Campana, L. G., Kurniawan, N. A., Lalaouna, D., Huttner, F. J., Ammerman, B. A., Ehret, F., Cobine, P. A., Tan, E. -C., Han, H., Xia, W., Mccrum, C., Dings, R. P. M., Marinello, F., Nilsson, H., Nixon, B., Voskarides, K., Yang, L., Costa, V. D., Bengtsson-Palme, J., Bradshaw, W., Grimm, D. G., Kumar, N., Martis, E., Prieto, D., Sabnis, S. C., Amer, S. E. D. R., Liew, A. W. C., Perco, P., Rahimi, F., Riva, G., Zhang, C., Devkota, H. P., Ogami, K., Basharat, Z., Fierz, W., Siebers, R., Tan, K. H., Boehme, K. A., Brenneisen, P., Brown, J. A. L., Dalrymple, B. P., Harvey, D. J., Ng, G., Werten, S., Bleackley, M., Dai, Z., Dhariwal, R., Gelfer, Y., Hartmann, M. D., Miotla, P., Tamaian, R., Govender, P., Gurney-Champion, O. J., Kauppila, J. H., Zhang, X., Echeverria, N., Subhash, S., Sallmon, H., Tofani, M., Bae, T., Bosch, O., Cuiv, P. O., Danchin, A., Diouf, B., Eerola, T., Evangelou, E., Filipp, F., Klump, H., Kurgan, L., Smith, S. S., Terrier, O., Tuttle, N., Ascher, D. B., Janga, S. C., Schulte, L. N., Becker, D., Browngardt, C., Bush, S. J., Gaullier, G., Ide, K., Meseko, C., Werner, G. D. A., Zaucha, J., Al-Farha, A. A., Greenwald, N. F., Popoola, S. I., Rahman, S., Xu, J., Yang, S. Y., Hiroi, N., Alper, O. M., Baker, C. I., Bitzer, M., Chacko, G., Debrabant, B., Dixon, R., Forano, E., Gilliham, M., Kelly, S., Klempnauer, K. -H., Lidbury, B. A., Lin, M. Z., Lynch, I., Ma, W., Maibach, E. W., Mather, D. E., Nandakumar, K. S., Ohgami, R. S., Parchi, P., Tressoldi, P., Xue, Y., Armitage, C., Barraud, P., Chatzitheochari, S., Coelho, L. P., Diao, J., Doxey, A. C., Gobet, A., Hu, P., Kaiser, S., Mitchell, K. M., Salama, M. F., Shabalin, I. G., Song, H., Stevanovic, D., Yadollahpour, A., Zeng, E., Zinke, K., Alimba, C. G., Beyene, T. J., Cao, Z., Chan, S. S., Gatchell, M., Kleppe, A., Piotrowski, M., Torga, G., Woldesemayat, A. A., Cosacak, M. I., Haston, S., Ross, S. A., Williams, R., Wong, A., Abramowitz, M. K., Effiong, A., Lee, S., Abid, M. B., Agarabi, C., Alaux, C., Albrecht, D. R., Atkins, G. J., Beck, C. R., Bonvin, A. M. J. J., Bourke, E., Brand, T., Braun, R. J., Bull, J. A., Cardoso, P., Carter, D., Delahay, R. M., Ducommun, B., Duijf, P. H. G., Epp, T., Eskelinen, E. -L., Fallah, M., Farber, D. B., Fernandez-Triana, J., Feyerabend, F., Florio, T., Friebe, M., Furuta, S., Gabrielsen, M., Gruber, J., Grybos, M., Han, Q., Heinrich, M., Helantera, H., Huber, M., Jeltsch, A., Jiang, F., Josse, C., Jurman, G., Kamiya, H., de Keersmaecker, K., Kristiansson, E., de Leeuw, F. -E., Li, J., Liang, S., Lopez-Escamez, J. A., Lopez-Ruiz, F. J., Marchbank, K. J., Marschalek, R., Martin, C. S., Miele, A. E., Montagutelli, X., Morcillo, E., Nicoletti, R., Niehof, M., O'Toole, R., Ohtomo, T., Oster, H., Palma, J. -A., Paterson, R., Peifer, M., Portilla, M., Portillo, M. C., Pritchard, A. L., Pusch, S., Raghava, G. P. S., Roberts, N. J., Ross, K., Schuele, B., Sergeant, K., Shen, J., Stella, A., Sukocheva, O., Uversky, V. N., Vanneste, S., Villet, M. H., Viveiros, M., Vorholt, J. A., Weinstock, C., Yamato, M., Zabetakis, I., Zhao, X., Ziegler, A., Aizat, W. M., Atlas, L., Bridges, K. M., Chakraborty, S., Deschodt, M., Domingues, H. S., Esfahlani, S. S., Falk, S., Guisado, J. L., Kane, N. C., Kueberuwa, G., Lau, C. L., Liang, D., Liu, E., Luu, A. M., Ma, C., Ma, L., Moyer, R., Norris, A. D., Panthee, S., Parsons, J. R., Peng, Y., Pinto, I. M., Reschke, C. R., Sillanpaa, E., Stewart, C. J., Uhle, F., Yang, H., Zhou, K., Zhu, S., Ashry, M., Bergsland, N., Berthold, M., Chen, C. -E., Colella, V., Cuypers, M., Eskew, E. A., Fan, X., Gajda, M., Gonzalezlez-Prendes, R., Goodin, A., Graham, E. B., Groen, E. J. N., Gutierrez-Sacristan, A., Habes, M., Heffler, E., Higginbottom, D. B., Janzen, T., Jayaraman, J., Jibb, L. A., Jongen, S., Kinyanjui, T., Koleva-Kolarova, R. G., Li, Z., Liu, Y. -P., Lund, B. A., Lussier, A. A., Mier, P., Moore, M. D., Nagler, K., Orme, M. W., Pearson, J. A., Prajapati, A. S., Saito, Y., Troder, S. E., Uchendu, F., Verloh, N., Voutchkova, D. D., Abu-Zaid, A., Bakkach, J., Baumert, P., Dono, M., Hanson, J., Herbelet, S., Hobbs, E., Kulkarni, A., Liu, S., Loft, N. D., Reddan, T., Senghore, T., Vindin, H., Xu, H., Bannon, R., Chen, B., Cheung, J. T. K., Cooper, J., Esnakula, A. K., Feghali, K. A., Ghelardi, E., Gnasso, A., Horbar, J., Lai, H. M., Ma, R., Pan, Z., Peres, M. A., Pranata, R., Seow, E., Sydes, M., Testoni, I., Westermair, A. L., Yang, Y., Afnan, M., Albiol, J., Albuquerque, L. G., Amir, S., Amiya, E., Amorim, R. M., An, Q., Andersen, S. U., Aplin, J. D., Argyropoulos, C., Asmann, Y. W., Assaeed, A. M., Atanasov, A. G., Atchison, D. A., Avery, S. V., Avillach, P., Baade, P. D., Backman, L., Badie, C., Baldi, A., Ball, E., Bardot, O., Barnett, A. G., Basner, M., Batra, J., Bazanova, O. M., Beale, A., Beddoe, T., Bell, M. L., Berezikov, E., Berners-Price, S., Bernhardt, P., Berry, E., Bessa, T. B., Billington, C., Birch, J., Blakely, R. D., Blaskovich, M. A. T., Blum, R., Boelaert, M., Bogdanos, D., Bosch, C., Bourgoin, T., Bouvard, D., Boykin, L. M., Bradley, G., Braun, D., Brownlie, J., Bruhl, A., Burt, A., Butler, L. M., Byrareddy, S. N., Byrne, H. J., Cabantous, S., Calatayud, S., Candal, E., Carlson, K., Casillas, S., Castelvetro, V., Caswell, P. T., Cavalli, G., Cerovsky, V., Chagoyen, M., Chen, C. -S., Chen, D. F., Chen, H., Chen, J. -T., Chen, Y., Cheng, C., Cheng, J., Chinapaw, M., Chinopoulos, C., Cho, W. C. S., Chong, L., Chowdhury, D., Chwalibog, A., Ciresi, A., Cockcroft, S., Conesa, A., Cook, P. A., Cooper, D. N., Coqueret, O., Corea, E. M., Costa, A., Costa, E., Coupland, C., Crawford, S. Y., Cruz, A. D., Cui, H., Cui, Q., Culver, D. C., D'Angiulli, A., Dahms, T. E. S., Daigle, F., Dalgleish, R., Danielsen, H. E., Darras, S., Davidson, S. M., Day, D. A., Degirmenci, V., Demaison, L., Devriendt, K., Ding, J., Dogan, Y., Dong, X. C., Donner, C. F., Dressick, W., Drevon, C. A., Duan, H., Ducho, C., Dumaz, N., Dwarakanath, B. S., Ebell, M. H., Eisenhardt, S., Elkum, N., Engel, N., Erickson, T. B., Fairhead, M., Faville, M. J., Fejzo, M. S., Festa, F., Feteira, A., Flood-Page, P., Forsayeth, J., Fox, S. A., Franks, S. 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M., Xiao, S., Xiong, P., Xu, S., Yao, R., Yao, W., Yin, Q., Zaitsu, M., Zeineb, Z., Zhan, X. -Y., Zhang, R., Zhang, W., Zheng, S., Zhou, B., Ahmad, H., Akinwumi, S. A., Albery, G. F., Alhowimel, A., Ali, J., Alshehri, M., Alsuhaibani, M., Anikin, A., Azubuike, S. O., Bach-Mortensen, A., Baltiansky, L., Bartas, M., Belachew, K. Y., Bhardwaj, V., Binder, K., Bland, N. S., Boah, M., Bullen, B., Calabro', Giovanna Elisa, Callahan, T. J., Cao, B., Chalmers, K., Chang, W., Che, Z., Chen, A. T. Y., Chen, Z., Choi, Y., Chowdhury, M. A. K., Christensen, M. R., Cooke, R. S. C., Cottini, M., Covington, N. V., Cunningham, C., Delarocque, J., Devos, L., Dhar, A. R., Ding, K. -F., Dong, K., Dong, Z., Dreyer, N., Ekstrand, C., Fardet, T., Feleke, B. E., Feurer, T., Freitas, A., Gao, T., Gebremedhin, Giganti, F., Grabowski, P., Guerra-Mora, J. R., Guo, C., Guo, X., Gupta, H., He, S., Heijne, M., Heinemann, S., Hogrebe, A., Huang, Z., Iskander-Rizk, S., Iyer, L. M., Jahan, Y., James, A. S., Joel, E., Joffroy, B., Jegousse, C., Kambondo, G., Karnati, P., Kaya, C., Ke, A., Kelly, D., Kickert, R., Kidibule, P. E., Kieselmann, J. P., Kim, H. J., Kitazawa, T., Lamberts, A., Liang, H., Linn, S. N., Litfin, T., Liusuo, W., Lygirou, V., Mahato, A. K., Mai, Z. -M., Major, R. W., Mali, S., Mallis, P., Mao, W., Marvin-Dowle, K., Mason, L. D., Merideth, B., Merino-Plaza, M. J., Merlaen, B., Messina, R., Mishra, A. K., Muhammad, J., Musinguzi, C., Nanou, A., Naqash, A., Nguyen, J. T., Nguyen, T. T. H., Ni, D., Nida, Notcovich, S., Ohst, B., Ollivier, Q. R., Osses, D. F., Peng, X., Plantinga, A., Pulia, M., Rafiq, M., Raman, A., Raucher-Chene, Rawski, R., Ray, A., Razak, L. A., Rudolf, K., Rusch, P., Sadoine, M. L., Schmidt, A., Schurr, R., Searles, S., Sharma, S., Sheehan, B., Shi, C., Shohayeb, B., Sommerlad, A., Strehlow, J., Sun, X., Sundar, R., Taherzadeh, G., Tahir, N. D. M., Tang, J., Testa, J., Tian, Z., Tingting, Q., Verheijen, G. P., Vickstrom, C., Wang, T., Wang, X., Wang, Z., Wei, P., Wilson, A., Wyart, Yassine, A. -A., Yousefzadeh, A., Zare, A., Zeng, Z., Zhang, H., Zhou, J., Zhu, D., Adamo, V., Adeyemo, A. A., Aggelidou, M., Al-Owaifeer, A. M., Al-Riyami, A. Z., Alzghari, S. K., Andersen, V., Angus, K., Asaduzzaman, M., Asady, H., Ato, D., Bai, X., Baines, R. L., Ballantyne, M., Ban, B., Beck, J., Ben-Nafa, W., Black, E., Blancher, A., Blankstein, R., Bodagh, N., Borges, P., Brooks, A., Brox-Ponce, J., Brunetti, A., Canham, C. D., Carninci, P., Carvajal, R., Chang, S. C., Chao, J., Chatterjee, P., Chen, L., Chhatriwalla, A. K., Chikowe, I., Chuang, T. -J., Collevatti, R. G., Cornejo, D. A. V., Cuenda, A., Dao, M., Dauga, D., Deng, Z., Devkota, K., Doan, L. V., Elewa, Y. H. A., Fan, D., Faruk, M., Feifei, S., Ferguson, T. S., Fleres, F., Foster, E. J., Foster, S., Furer, T., Gao, Y., Garcia-Rivera, E. J., Gazdar, A., George, R. B., Ghosh, S., Gianchecchi, E., Gleason, J. M., Hackshaw, A., Hall, A., Hall, R., Harper, P., Hogg, W. E., Huang, G., Hunter, K. E., Ijzerman, A. P., Jesus, C., Jian, G., Lewis, J. S., Kanj, S. S., Kaur, H., Kheir, F., Kichatova, V. S., Kiyani, M., Klein, R., Kovesi, T., Kraschnewski, J. L., Kumar, A. P., Labutin, D., Lazo-Langner, A., Leclercq, G., Li, M., Li, Q., Li, T., Liao, W. -T., Liao, Z. -Y., Lin, J., Lizer, J., Lobreglio, G., Lowies, C., Lu, C., Majeed, H., Martin, A., Martinez-Sobrido, L., Meresh, E., Middelveen, M., Mohebbi, A., Mota, J., Mozaheb, Z., Muyaya, L., Nandhakumar, A., Ng, S. H. X., Obeidat, M., Oh, D. -H., Owais, M., Pace-Asciak, P., Panwar, A., Patterson, C., Penagos-Tabaree, F., Pianosi, P. T., Pinzi, V., Pridans, C., Psaroulaki, A., Pujala, R. K., Pulido-Arjona, L., Qi, P. -F., Rahman, P., Rai, N. K., Rassaf, T., Refardt, J., Ricciardi, Walter, Riess, O., Rovas, A., Sacks, F. M., Saleh, S., Sampson, C., Schmutz, A., Sepanski, R., Sharma, N., Spearman, P., Subramaniapillai, M., Swali, R., Tan, C. M., Tellechea, J. I., Thomas, L. -M., Tong, X., Vavvas, D. G., Veys, R., Vitriol, V., Wang, H. -D., Waugh, J., Webb, S. A., Williams, B. A., Workman, A. D., Xiang, T., Xie, L. -X., Xu, T., Yang, C., Yoon, J. G., Yuan, C. M., Zaritsky, A., Zhao, H., Zuckerman, H., Lyu, R., Pullan, W., Calabro G. E. (ORCID:0000-0003-0259-3797), and Ricciardi W. (ORCID:0000-0002-5655-688X)
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
- Published
- 2019
43. A Note on the Evaluation of the Complementary Error Function
- Author
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Hunter, D. B. and Regan, T.
- Published
- 1972
- Full Text
- View/download PDF
44. An improved system for the targeted mutagenesis of thepsbA2gene inSynechocystissp. PCC 6803: mutation of D1-Glu244 to His impairs electron transfer between QAand QBof Photosystem II
- Author
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Forsman, Jack A., primary, Winter, Regan T., additional, and Eaton-Rye, Julian J., additional
- Published
- 2019
- Full Text
- View/download PDF
45. Impact of Nonlinear Phase Noise on All-Optical Wavelength Conversion of 10.7-GBaud QPSK Data Using Dual Correlated Pumps
- Author
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Aravind P. Anthur, Regan T. Watts, Sean O'Duill, null Rui Zhou, Deepa Venkitesh, and Liam P. Barry
- Subjects
Electrical and Electronic Engineering ,Condensed Matter Physics ,Engineering sciences. Technology ,Atomic and Molecular Physics, and Optics - Published
- 2015
46. T CELL HYPOTHESIS IN RHEUMATOID ARTHRITIS (RA) TESTED BY HUMANISED NON-DEPLETING ANTI-CD4 MONOCLONAL ANTIBODY (mAb) TREATMENT I: SUPPRESSION OF DISEASE ACTIVITY AND ACUTE PHASE RESPONSE.: OGg379
- Author
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Panayi, G S, Choy, E HS, Connolly, D JA, Manna, V K, Regan, T, Rapson, N, Kingsley, G H, and Johnston, J M
- Published
- 1996
47. T CELL HYPOTHESIS IN RHEUMATOID ARTHRITIS (RA) TESTED BY HUMANISED NON-DEPLETING ANTI-CD4 MONOCLONAL ANTIBODY (mAb) TREATMENT II: CLINICAL ACTIVITY IS RELATED TO PHARMACODYNAMIC EFFECTS.: OGg378
- Author
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Choy, E HS, Connolly, D JA, Regan, T, Manna, V K, Rapson, N, Kingsley, G H, Panayi, G S, and Johnston, J M
- Published
- 1996
48. Immune cell gene signatures for profiling the microenvironment of solid tumors
- Author
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Nirmal, A.J., Regan, T., Shih, B.B., Hume, D.A., Sims, A.H., Freeman, T.C., Nirmal, A.J., Regan, T., Shih, B.B., Hume, D.A., Sims, A.H., and Freeman, T.C.
- Abstract
The immune composition of the tumor microenvironment regulates processes including angiogenesis, metastasis, and the response to drugs or immunotherapy. To facilitate the characterization of the immune component of tumors from transcriptomics data, a number of immune cell transcriptome signatures have been reported that are made up of lists of marker genes indicative of the presence a given immune cell population. The majority of these gene signatures have been defined through analysis of isolated blood cells. However, blood cells do not reflect the differentiation or activation state of similar cells within tissues, including tumors, and consequently markers derived from blood cells do not necessarily transfer well to tissues. To address this issue, we generated a set of immune gene signatures derived directly from tissue transcriptomics data using a network-based deconvolution approach. We define markers for seven immune cell types, collectively named ImSig, and demonstrate how these markers can be used for the quantitative estimation of the immune cell content of tumor and nontumor tissue samples. The utility of ImSig is demonstrated through the stratification of melanoma patients into subgroups of prognostic significance and the identification of immune cells with the use of single-cell RNA-sequencing data derived from tumors. Use of ImSig is facilitated by an R package (imsig).
- Published
- 2018
49. Systematic review of interventions to increase the provision of care for chronic disease risk behaviours in mental health settings: review protocol.
- Author
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Fehily, C, Bartlem, K, Wiggers, J, Wolfenden, L, Regan, T, Dray, J, Bailey, J, Bowman, J, Fehily, C, Bartlem, K, Wiggers, J, Wolfenden, L, Regan, T, Dray, J, Bailey, J, and Bowman, J
- Abstract
BACKGROUND: People with a mental illness experience a higher morbidity and mortality from chronic diseases relative to the general population. A higher prevalence of risk behaviours, including tobacco smoking, poor nutrition, harmful alcohol consumption and physical inactivity, is a substantial contributor to this health inequity. Clinical practice guidelines recommend that mental health services routinely provide care to their clients to address these risk behaviours. Such care may include the following elements: ask, assess, advise, assist and arrange (the '5As'), which has been demonstrated to be effective in reducing risk behaviours. Despite this potential, the provision of such care is reported to be low internationally and in Australia, and there is a need to identify effective strategies to increase care provision. The proposed review will examine the effectiveness of interventions which aimed to increase care provision (i.e. increase the proportion of clients receiving or clinicians providing the 5As) for the chronic disease risk behaviours of clients within the context of mental health service delivery. METHODS: Eligible studies will be any quantitative study designs with a comparison group and which report on the effectiveness of an intervention strategy (including delivery arrangements, financial arrangements, governance arrangements and implementation strategies) to increase care provision specifically for chronic disease risk behaviours (tobacco smoking, poor nutrition, harmful alcohol consumption and physical inactivity). Screening for studies will be conducted across seven electronic databases: PsycINFO, MEDLINE, Excerpta Medica database (EMBASE), Psychology and Behavioural Sciences Collection, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL) and Cumulative Index to Nursing and Allied Health Literature (CINAHL). Two authors will independently screen studies for eligibility and extract data from included studies. Where studies are suffi
- Published
- 2018
50. Exploring the microscopic origin of exchange bias with photoelectron emission microscopy (invited)
- Author
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Scholl, A., Nolting, F., Stohr, J., Regan, T., Luning, J., Seo, J.W., Locquet, J.-P., Fompeyrine, J., Anders, S., Ohldag, H., and Padmore, H.A.
- Subjects
Antiferromagnetism -- Research ,Ferromagnetism -- Research ,Thin films -- Magnetic properties ,Physics - Abstract
It has been possible to apply photoelectron emission microscopy on a number of ferromagnet-antiferromagnet thin-film structures. This research involved microscopically imaging the ferromagnetic and the antiferromagnetic structure with high spatial resolution.
- Published
- 2001
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