1. Cerebral magnetic resonance imaging compared in Alzheimer's and multi-infarct dementia
- Author
-
Reed Km, Meyer Js, and Rogers Rl
- Subjects
medicine.diagnostic_test ,business.industry ,Brain ,Magnetic resonance imaging ,Senile dementia ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,White matter ,Psychiatry and Mental health ,medicine.anatomical_structure ,Dementia, Multi-Infarct ,Discriminant function analysis ,Alzheimer Disease ,Cohort ,cardiovascular system ,medicine ,Dementia ,Humans ,cardiovascular diseases ,Neurology (clinical) ,Alzheimer's disease ,Nuclear medicine ,business ,Aged - Abstract
Cerebral magnetic resonance images (MRI) were compared between two groups, each of 25 patients, one with senile dementia of the Alzheimer's type (SDAT) and the other with multi-infarct dementia (MID). MRI proved to be clinically useful for differentiating SDAT from MID, utilizing a multivariate model of six MRI criteria as follows: ventricular-brain ratio, presence of subcortical infarcts, bifrontal ventricular ratio, bicaudate ventricular ratio, third ventricular ratio, and presence of diffuse periventricular high-intensity white matter lucencies. Utilizing all six MRI criteria, classification by discriminant function analysis provided 84% correct diagnostic agreement with clinical classification of MID patients, 92% for SDAT patients, and 88% for the total cohort of demented patients.
- Published
- 1991