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26 results on '"Reddy, Jay W"'

2. Parylene Photonics: A Flexible, Broadband Optical Waveguide Platform with Integrated Micromirrors for Biointerfaces

Author

Reddy, Jay W., Lassiter, Maya, and Chamanzar, Maysamreza

Subjects
Physics - Applied Physics
Abstract

Targeted light delivery into biological tissue is needed in applications such as optogenetic stimulation of the brain and in vivo functional or structural imaging of tissue. These applications require very compact, soft, and flexible implants that minimize damage to tissue. Here, we demonstrate a novel implantable photonic platform based on a high-density, flexible array of ultracompact (30 ${\mu}$m x 5 ${\mu}$m), low-loss (3.2 dB/cm at ${\lambda}$ = 680 nm, 4.1 dB/cm at ${\lambda}$ = 633 nm, 4.9 dB/cm at ${\lambda}$ = 532 nm, 6.1 dB/cm at ${\lambda}$ = 450 nm) optical waveguides made of biocompatible polymers Parylene C and polydimethylsiloxane (PDMS). This photonic platform features unique embedded input/output micro-mirrors that redirect light from the waveguides perpendicularly to the surface of the array for localized, patterned illumination in tissue. This architecture enables the design of a fully flexible, compact integrated photonic system for applications such as in vivo chronic optogenetic stimulation of brain activity., Comment: 20 pages, 7 figures, submitted to Nature Microsystems and Nanoengineering

Published
2020
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7. CMU Array: A 3D nanoprinted, fully customizable high-density microelectrode array platform

Author

Saleh, Mohammad Sadeq, primary, Ritchie, Sandra M., additional, Nicholas, Mark A., additional, Gordon, Hailey L., additional, Hu, Chunshan, additional, Jahan, Sanjida, additional, Yuan, Bin, additional, Bezbaruah, Rriddhiman, additional, Reddy, Jay W., additional, Ahmed, Zabir, additional, Chamanzar, Maysamreza, additional, Yttri, Eric A., additional, and Panat, Rahul P., additional

Published
2022
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8. Flexible optoelectric neural interfaces

Author

Ahmed, Zabir, primary, Reddy, Jay W, additional, Malekoshoaraie, Mohammad H, additional, Hassanzade, Vahid, additional, Kimukin, Ibrahim, additional, Jain, Vishal, additional, and Chamanzar, Maysamreza, additional

Published
2021
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25. Parylene Photonic Microimager for Implantable Imaging .

Author

Reddy JW, Malekoshoaraie MH, Hassanzade V, Venkateswaran R, and Chamanzar M

Subjects
Animals, Electrodes, Implanted, Mice, Polymers, Optics and Photonics, Xylenes
Abstract

We have recently introduced a fully flexible, compact photonic platform, Parylene photonics. Here, we demonstrate a Parylene photonic waveguide array microimager with a light source localization accuracy of 17.04 µm along the x-axis and 30.07 µm along the y-axis over a 200 µm×1000 µm region. We show the feasibility of fluorescent imaging from mouse brain tissue using the microimager array.Clinical Relevance- Implantable microimagers can be used for clinical intraoperative monitoring as well as structural and functional imaging with cell-type specificity in research.

Published
2021
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26. A Semi-Automated System for Wafer-Scale Optical Waveguide Characterization.

Author

Venkateswaran R, Reddy JW, and Chamanzar M

Subjects
Equipment Design, Humans, Optics and Photonics
Abstract

Integrated photonic waveguide systems are used in biomedical sensing and require robust, high-throughput methods of characterization. Here, we demonstrate a semi-automated robotic system to characterize waveguides at the wafer-scale with minimal human intervention based on imaging the outscattered light to measure the propagation loss. We demonstrate automated input coupling efficiency optimization using closed-loop control of the input fiber position. The automated characterization system collects and combines multiple images of the waveguide to measure the propagation loss. This system allows high-throughput characterization of integrated photonic waveguides and lays the foundation for a fully automated and high throughput system to characterize photonic waveguides at the wafer scale.Clinical Relevance- This method enables high precision, high throughput characterization of optoelectrical neural probes to maximize the yield of surgical implantation and electrophysiology recording.

Published
2021
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