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Background: Kidney transplantation success can help improve the quality of life substantially and alleviate much of the physical, social and psychological stress that comes with dialysis lifestyle. Preemptive kidney transplantation has been established to be superior with more success rates than other means of transplantation types. However, low rates of this method need more attention to address the reason and tackle the root causes affecting low preemptive kidney transplantation. Methods: This study was undertaken at a tertiary care academic hospital. We conducted a retrospective chart review of 50 living donor kidney transplants (recipient and donor charts) between January 1, 2017 and September 30, 2018 and performed a root cause analysis on the module. A three-step algorithm was developed to divide the root cause of all preemptive kidney transplantation. Results: Out of 50 patients included, only 11 (22%) achieved a successful preemptive kidney transplantation. Furthermore, an estimated glomerular filtration rate (eGFR) of 15 - 20 was a significant factor in achieving preemptive kidney transplantation (P = 0.042). Meanwhile, 22 recipients started dialysis before transplant and was a major cause of not achieving the preemptive transplantation despite them achieving the status. Moreover, the most common recipient root cause was incidental medical issues in 10 cases (20%) while in donor factors, the most common root cause was the delay in evaluating multiple donors to achieve the preemptive status (20%). Conclusion: Even though preemptive kidney transplantation is superior when compared to other modalities, achieving such a milestone is still considered very challenging. An eGFR of 15 - 20 was a significant factor in achieving preemptive kidney transplantation, while pre-transplant dialysis was a major cause of not achieving it. Further large-scale studies are needed to identify new factors as well as validate our findings. J Clin Med Res. 2021;13(1):1-8 doi: https://doi.org/10.14740/jocmr4391

Background The importance of effective communication during public health emergencies has been highlighted by the World Health Organization, and it has published guidelines for effective communication in such situations. With video being a popular medium, video communication has been a growing area of study over the past decades and is increasingly used across different sectors and disciplines, including health. Health-related video communication gained momentum during the SARS-CoV-2 pandemic, and video was among the most frequently used modes of communication worldwide. However, although much research has been done regarding different characteristics of video content (the message) and its delivery (the messenger), there is a lack of knowledge about the role played by the characteristics of the recipients for the creation of effective communication. Objective The aim of this review is to identify how health video communication outcomes are shaped by recipient characteristics, as such characteristics might affect the effectiveness of communication. The main research question of the study is as follows: do the characteristics of the recipients of health videos affect the outcomes of the communication? Methods A scoping review describing the existing knowledge within the field was conducted. We searched for literature in 3 databases (PubMed, Scopus, and Embase) and defined eligibility criteria based on the relevance to the research question. Recipient characteristics and health video communication outcomes were identified and classified. Results Of the 1040 documents initially identified, 128 (12.31%) met the criteria for full-text assessment, and 39 (3.75%) met the inclusion criteria. The included studies reported 56 recipient characteristics and 42 communication outcomes. The reported associations between characteristics and outcomes were identified, and the potential research opportunities were discussed. Contributions were made to theory development by amending the existing framework of the Integrated-Change model, which is an integrated model of motivational and behavioral change. Conclusions Although several recipient characteristics and health video communication outcomes were identified, there is a lack of robust empirical evidence on the association between them. Further research is needed to understand how the preceding characteristics of the recipients might affect the various outcomes of health video communication.

Die Zahl der Patienten mit terminaler Niereninsuffizienz nimmt stetig zu. Die angewendeten Verfahren der Nierenersatztherapie sind Hämodialyse, Peritonealdialyse und die Nierentrans-plantation. Letztere konnte sich mittlerweile aufgrund verbesserter therapeutischer und diagno-stischer Optionen und weiterentwickelter Immunsuppressiva als erfolgreiches und sicheres The-rapieverfahren etablieren. Dies äußert sich in verbesserten Transplantatüberlebensraten. Es sind zahlreiche Faktoren in der Literatur beschrieben, die das Transplantatüberleben unterschiedlich beeinflussen. Grundsätzlich werden nach ätiologischen Gesichtspunkten immunologische (allo- antigen-abhängige) von nichtimmunologischen (alloantigen-unabhängige) Risikofaktoren unter-schieden. Ziel dieser klinischen Studie war die retrospektive Analyse der Auswirkung von nicht-immunologischen Empfängerfaktoren auf das Nierentransplantat- und Patientenüberleben bei Lebend- und postmortalen Spenden. 512 untersuchte Patienten wurden im Zeitraum vom 01.01.2001 bis zum 31.12.2005 an der Klinik für Allgemein-, Visceral- und Transplantations-chirurgie des Virchow-Klinikums der Medizinischen Fakultät Charité-Universitätsmedizin Ber-lin operiert. Die mittlere Nachbeobachtungszeit betrug 3,35 Jahre und endete am 31.12.2006. Der statistische Nachweis signifikanter Einflussfaktoren erfolgte mit dem Chi- Quadrat-Vierfeldertest nach Pearson. Die Patienten- und Transplantatüberlebenskurven wurden mit der Kaplan-Meier-Methode berechnet. Die multivariate Analyse erfolgte mit dem Regressionsmodell nach Cox. Von allen untersuchten nichtimmunologischen Empfängerfaktoren hatten die kardiovaskulären Erkrankungen und die Arteriosklerose einen signifikant negativen Einfluss auf das Transplantat- und das Patientenüberleben. Das fortgeschrittene Empfängeralter zum Zeitpunkt der Transplan-tation übte einen signifikant negativen Einfluss auf das Patientenüberleben aus. Interessanterwei-se hatte die Glomerulonephritis bei den untersuchten Patienten verglichen mit den anderen häu-figen Grunderkrankungen einen signifikant positiven Effekt auf das Patientenüberleben., Over the recent years, the number of patients with chronic kidney disease has been increasing constantly. Renal replacement therapies including hemodialysis, peritoneal dialysis and renal transplantation have been used as a supportive and causal treatment, respectively, for decades. Because of improved therapeutical and diagnostical options as well as advanced immunosup- pressives renal transplantation has become a successful and safe procedure. This translates into improved transplant survival rates. There are many observations about the influencing factors of long-term allotransplant survival in literature. They are classified etiologically as immunological and non-immunological risk factors. The aim of this study was a retrospective analysis of the effect of non-immunological recipient factors on the transplant and patient survival. The data included both living and deceased donor procedures. 512 transplant patients operated between January 1st, 2001 and December 31st, 2005 at the Charité, Campus Virchow-Klinikum, Klinik für Allgemein-, Visceral- und Transplanta-tionschirurgie, Berlin, Germany were investigated. The mean time of follow up was 3,35 years and the observation period ended at December 31st, 2006. The Chi-square test was used after the Pearson test to assess significance, Kaplan-Meier method was used to calculate graft and patient survivals. The proportional hazard regression model indicated factors influencing graft and pa-tient survival. Among the examined non-immunological recipient factors cardiovascular disease and arterio- sclerosis had a significant negative impact on transplant and patient survival rates. Advanced recipient age had a significant negative effect on patient survival rates. Interestingly, glomerulo-nephritis had a significant positive influence on patient survival compared to other causes of chronic kidney disease such as polycystic kidney disease and toxin-induced chronic tubulointer-stitial nephritis.