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1,029 results on '"Receptors, Estrogen chemistry"'

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1. In Silico Prediction of ERRα Agonists Based on Combined Features and Stacking Ensemble Method.

2. The C-terminal self-binding helical peptide of human estrogen-related receptor γ can be druggably targeted by a novel class of rationally designed peptidic antagonists.

3. Screening of BindingDB database ligands against EGFR, HER2, Estrogen, Progesterone and NF-κB receptors based on machine learning and molecular docking.

4. Insight into the Binding Interaction between PEDCs and hERRγ Utilizing Molecular Docking and Molecular Dynamics Simulations.

5. Identification of pseudobaptigenin as a novel polyphenol-based multi-target antagonist of different hormone receptors for breast cancer therapeutics.

6. Structure-based drug design-guided identification of estrogen receptor binders.

7. Rational evolution for altering the ligand preference of estrogen receptor alpha.

8. Research progress on tamoxifen and its analogs associated with nuclear receptors.

9. A molecular dynamics perspective into estrogen receptor inhibition by selective flavonoids as alternative therapeutic options.

10. G protein-coupled estrogen receptor-1: homology modeling approaches and application in screening new GPER-1 modulators.

11. Natural bioactive compounds as a new source of promising G protein-coupled estrogen receptor (GPER) modulators: comprehensive in silico approach.

12. Challenging Approach to the Development of Novel Estrogen Receptor Modulators Based on the Chemical Properties of Guaiazulene.

13. The physiological role of estrogen receptor functional domains.

14. Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer.

15. Protein druggability assessment for natural products using in silico simulation: A case study with estrogen receptor and the flavonoid genistein.

16. ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes.

17. Estrogen Receptor Modulators in Viral Infections Such as SARS-CoV-2: Therapeutic Consequences.

18. Identification of homozygous mutations for hearing loss.

19. FBXL10 promotes ERRα protein stability and proliferation of breast cancer cells by enhancing the mono-ubiquitylation of ERRα.

20. ERRγ ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype.

21. Estrogen Receptors in Polycystic Ovary Syndrome.

22. Endocrine disruption: the noise in available data adversely impacts the models' performance.

23. Theoretical study on endocrine disrupting effects of polychlorinated dibenzo-p-dioxins using molecular docking simulation.

24. A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses.

25. Sexual hormones and diabetes: The impact of estradiol in pancreatic β cell.

26. The role of ERα36 in cell type-specific functions of estrogen and cancer development.

27. Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure.

28. Quantifying DNA End Resection in Human Cells.

29. Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.

30. Estrogen receptor agonists protect against acetaminophen-induced hepatorenal toxicity in rats.

31. An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.

32. Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor β.

33. Anticancer Melatplatin Prodrugs: High Effect and Low Toxicity, MT1-ER-Target and Immune Response In Vivo .

34. Estrogen receptor-mediated targeting of the extracellular matrix network in cancer.

35. GPR30 expression and function in breast cancer cells are induced through a cis‑acting element targeted by ETS factors.

36. Gasdermin E suppresses tumour growth by activating anti-tumour immunity.

37. Molecular modelling methods in food safety: Bisphenols as case study.

38. Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology.

39. Androgen receptor-binding sites are highly mutated in prostate cancer.

40. The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E-mediated pyroptosis.

41. Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer.

42. Subresidue-Resolution Footprinting of Ligand-Protein Interactions by Carbene Chemistry and Ion Mobility-Mass Spectrometry.

43. Gonadal Hormones and Bone.

44. Insights into the activation mechanism of human estrogen-related receptor γ by environmental endocrine disruptors.

45. Estrogen-related receptor β activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma.

46. Genome-Wide Analysis of the FABP Gene Family in Liver of Chicken (Gallus gallus): Identification,Dynamic Expression Profile, and RegulatoryMechanism.

47. Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water samples.

48. Estrogen-related receptor γ is a novel target for Lower-Chlorinated Polychlorinated Biphenyls and their hydroxylated and sulfated metabolites.

49. A modular PROTAC design for target destruction using a degradation signal based on a single amino acid.

50. A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.

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