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6. Digitalizzazione, Ricerca clinica e Medicina, tra cambi di paradigma, 'comodità e socialità' [Digitalization, clinical research and medicine, between paradigm shifts, user-friendliness and social relations]

Author

Borgonovi, E., Bellardita, L., Capolongo, S., Collicelli, C., Da Ros, L., Durst, L., Gussoni, G., Mannelli, C., Petrini, C., Recchia, G., Trogu, P., and Zagarrì, E.

Subjects
user-friendliness, medicine, clinical research, Ricerca clinica, Medicina, Digitalizzazione, social aspect, Edilizia sanitaria, Digitalizzazione, Ricerca clinica, Medicina, social aspect, healthcare design, Digitalization, social relations, Edilizia sanitaria, healthcare design, Digitalization, clinical research, medicine, user-friendliness, social relations
Published
2022

8. Arterial and venous thrombosis in coronavirus 2019 disease (Covid-19):relationship with mortality

Author

Violi, F., Ceccarelli, G., Cangemi, R., Cipollone, F., D'Ardes, D., Oliva, A., Pirro, M., Rocco, M., Alessandri, F., D'Ettorre, G., Lichtner, M., Pignatelli, P., Ferro, D., Ruberto, F., Lip, G. Y. H., Pugliese, F., Mastroianni, C. M., Albante, A., Auricchio, D., De Lazzaro, F., M. De Lauri D., Di Santo, C., Ianni, S., Magnanimi, E., Ratini, F., Sabani, A., Titi, L., Vaccaro, P., Giordano, G., Manganelli, C., Mancone, M., Bruno, K., Celli, P., Consolo, S., Croce, C., Giannetti, L., Martelli, S., Messina, T., Pattelli, E., Perrella, S., Portieri, M., Ricci, C., Almenrader, N., Arzilla, R., Delia, E., Di Giovanni, C., Laderchi, A., Macri, C., Marandola, M., Nardecchia, G., Pacilli, M., Pacini, F., Araimo Morselli, F., Imperiale, C., Tordiglione, P., Ciardi, M. R., Ajassa, C., D'Agostino, C., Russo, G., Trinchieri, V., Guariglia, P., Antonelli, L., Cuomo, R. M., Carnevalini, M., Mastropietro, C., Iaiani, G., Mezzaroma, I., Falciano, M., Brogi, A., Celani, L., Cavallari, N. E., Rivano Capparuccia, M., Massetti, A. P., Fimiani, C., Santori, M., Bianchi, A., Franchi, C., De Angelis, M., Sereno, S., Furlan, C., De Sanctis, G., Paoletti, F., Pasculli, P., Cogliati Dezza, F., Vassalini, P., Cancelli, F., De Girolamo, G., Savelloni, G., Valeri, S., Siccardi, G., Alessi, F., Recchia, G., Ridolfi, M., Romani, F. E., Aronica, R., Filippi, V., Vera, M., Volpicelli, L., Candy, M., Alban, R., Di Bari, S., Gavaruzzi, F., Casali, E., Carli, M. S., Zingaropoli, A. M., Perri, V., Santinelli, L., Pinacchio, C., Nijhawan, P., Miele, C. M., Innocenti, P. G., and Mengoni, F.

Subjects
Male, covid-19, mortality, sars-cov-2, thrombosis, Coronary Artery Disease, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, law.invention, Coronary artery disease, 0302 clinical medicine, law, 80 and over, Coronary Artery Disease/epidemiology, Odds Ratio, SARS-cov-2, 030212 general & internal medicine, Prospective Studies, Aged, 80 and over, Thromboembolism/epidemiology, biology, Hazard ratio, Middle Aged, Mortality/trends, Intensive care unit, Thrombosis, Venous thrombosis, Intensive Care Units, C-Reactive Protein, Emergency Medicine, Cardiology, COVID-19/complications, Female, medicine.medical_specialty, Fibrin Fibrinogen Degradation Products/analysis, Fibrin Fibrinogen Degradation Products, 03 medical and health sciences, C-Reactive Protein/analysis, Internal medicine, Thromboembolism, Internal Medicine, medicine, Humans, Mortality, Aged, Proportional Hazards Models, Intensive Care Units/organization & administration, business.industry, C-reactive protein, COVID-19, Odds ratio, medicine.disease, Im - Original, Logistic Models, Heart failure, biology.protein, business
Abstract

Background Patients with coronavirus disease 2019 (Covid-19) may experience venous thrombosis while data regarding arterial thrombosis are sparse. Methods Prospective multicenter study in 5 hospitals including 373 patients with Covid-19-related pneumonia. Demographic data, laboratory findings including coagulation tests and comorbidities were reported. During the follow-up any arterial or venous thrombotic events and death were registered. Results Among 373 patients, 75 (20%) had a thrombotic event and 75 (20%) died. Thrombotic events included 41 venous thromboembolism and 34 arterial thrombosis. Age, cardiovascular disease, intensive care unit treatment, white blood cells, D-dimer, albumin and troponin blood levels were associated with thrombotic events. In a multivariable regression logistic model, intensive care unit treatment (Odds Ratio [OR]: 6.0; 95% Confidence Interval [CI] 2.8–12.6; p p = 0.022); and albumin levels (OR: 0.49; 95% CI 0.28–0.87; p = 0.014) were associated with ischemic events. Age, sex, chronic obstructive pulmonary disease, diabetes, heart failure, coronary heart disease, intensive care unit treatment, in-hospital thrombotic events, D-dimer, C-reactive protein, troponin, and albumin levels were associated with mortality. A multivariable Cox regression analysis showed that in-hospital thrombotic events (hazard ratio [HR]: 2.72; 95% CI 1.59–4.65; p p = 0.001), and albumin (HR: 0.447; 95% CI 0.277–0.723; p = 0.001) predicted morality. Conclusions Covid-19 patients experience an equipollent rate of venous and arterial thrombotic events, that are associated with poor survival. Early identification and appropriate treatment of Covid-19 patients at risk of thrombosis may improve prognosis.

Published
2021

9. Italian Guidelines in patch testing - Adapted from the European Society of Contact Dermatitis (ESCD)

Author

Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Stingeni, L., Bianchi, L., Hansel, K., Corazza, M., Gallo, R., Guarneri, F., Patruno, C., Rigano, L., Romita, P., Pigattoatt, P. D., Calzavara-Pintoton, P., Agostinelli, S., Albertazzi, D., Angelini, G., Angerosa, F., Arigliano, P. L., Assalve, D., Ayala, F., Bellonifortina, A., Berta, M., Biale, C., Biasini, I., Boccaletti, V., Bonamonte, D., Borghi, A., Brambilla, L., Bressan, M., Bruno, A., Caccavale, S., Calogiuri, G., Cannavò, S. P., Carugno, A., Cataldi, I., Chiarelli, G., Chiesa, A., Cirla, A. M., Cossutta, M., Cova, L. M., Cristaudo, A., Dalcan-Ton, M., Damiani, G., Danese, P., Desalvo, V., Fantini, C., Ferrucci, S. M., Flori, M. L., Fontana, E., Foti, C., Francalanci, S., Frasin, L. A., Gola, M., Gravante, M., Guastaferro, D., Ingordo, V., Lauriola, M. M., Leghissa, P., Lisi, P., Lombardi, P., Lorenzini, M., Magrini, L., Marone, G., Martina, E., Mascagni, P., Matteinichiari, M., Meligeni, L., Melino, M., Milanesi, N., Molinu, A. A., Monfrecola, G., Morelli, P., Motolese, A., Musumeci, M. L., Napolitano, M., Nasca, M. R., Paganini, P., Papini, M., Pasolini, G., Peroni, A., Peserico, A., Piras, V., Pugliese, A., Raponi, F., Raviolo, P. D., Rebora, A., Recchia, G. P., Riva, F., Rossi, M., Ruggieri, M., Saggiorato, F., Sartorelli, P., Schena, D., Schettino, A., Spano, G., Stinchi, C., Taddei, L., Tasin, L., Tramontana, M., Valsecchi, R. H., Vascellaro, A., Venturini, M., Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Stingeni, L., Bianchi, L., Hansel, K., Corazza, M., Gallo, R., Guarneri, F., Patruno, C., Rigano, L., Romita, P., Pigattoatt, P. D., Calzavara-Pintoton, P., Agostinelli, S., Albertazzi, D., Angelini, G., Angerosa, F., Arigliano, P. L., Assalve, D., Ayala, F., Bellonifortina, A., Berta, M., Biale, C., Biasini, I., Boccaletti, V., Bonamonte, D., Borghi, A., Brambilla, L., Bressan, M., Bruno, A., Caccavale, S., Calogiuri, G., Cannavò, S. P., Carugno, A., Cataldi, I., Chiarelli, G., Chiesa, A., Cirla, A. M., Cossutta, M., Cova, L. M., Cristaudo, A., Dalcan-Ton, M., Damiani, G., Danese, P., Desalvo, V., Fantini, C., Ferrucci, S. M., Flori, M. L., Fontana, E., Foti, C., Francalanci, S., Frasin, L. A., Gola, M., Gravante, M., Guastaferro, D., Ingordo, V., Lauriola, M. M., Leghissa, P., Lisi, P., Lombardi, P., Lorenzini, M., Magrini, L., Marone, G., Martina, E., Mascagni, P., Matteinichiari, M., Meligeni, L., Melino, M., Milanesi, N., Molinu, A. A., Monfrecola, G., Morelli, P., Motolese, A., Musumeci, M. L., Napolitano, M., Nasca, M. R., Paganini, P., Papini, M., Pasolini, G., Peroni, A., Peserico, A., Piras, V., Pugliese, A., Raponi, F., Raviolo, P. D., Rebora, A., Recchia, G. P., Riva, F., Rossi, M., Ruggieri, M., Saggiorato, F., Sartorelli, P., Schena, D., Schettino, A., Spano, G., Stinchi, C., Taddei, L., Tasin, L., Tramontana, M., Valsecchi, R. H., Vascellaro, A., and Venturini, M.

Abstract

Patch testing is the standard procedure used to diagnose allergic contact dermatitis. It is an in-vivo test, which reproduces the reaction to a contact allergen. This in-vivo test aims to reproduce the elicitation phase of allergic contact dermatitis and is performed applying allergens under occlusion on the skin under standardized conditions. These guidelines for the best practice in performing patch test have been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Society of Contact Dermatitis (ESCD) and on the basis of the SIDAPA guidelines.

Published
2019

11. Clinical impact of the predict prostate risk communication tool in men newly diagnosed with non-metastatic prostate cancer: A multi-centre randomised controlled trial

Author

Thurtle, D., primary, Jenkins, V., additional, Freeman, A., additional, Pearson, M., additional, Recchia, G., additional, Tamer, P., additional, Leonard, K., additional, Pharoah, P.D., additional, Aning, J., additional, Madaan, S., additional, Goh, C., additional, Hilman, S., additional, Mccracken, S., additional, Ilie, C., additional, Lazarowicz, H., additional, and Gnanapragasam, V., additional

Published
2021
Full Text
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15. Reaching across the Adriatic: northern and western interactions of the Cetina phenomenon (25th–20th centuries BC) / Kroz i preko Jadrana: sjeverna i zapadna interakcija fenomena Cetinske kulture (25–20. v. pr. Hr.)

Author

Recchia, G.

Subjects
Cetina Phenomenon, Cross-cul-tural Interactions, Northern and Western Adriatic, Cetina Phenomenon, Northern and Western Adriatic, Second half of the 3rd Millennium BC, Cross-cul-tural Interactions, Second half of the 3rd Millennium BC
Published
2021

21. Cardiometabolic multimorbidity is associated with a worse Covid-19 prognosis than individual cardiometabolic risk factors: a multicentre retrospective study (CoViDiab II)

Author

Maddaloni, E., D'Onofrio, L., Alessandri, F., Mignogna, C., Leto, G., Pascarella, G., Mezzaroma, I., Lichtner, M., Pozzilli, P., Agro, F. E., Rocco, M., Pugliese, F., Lenzi, A., Holman, R. R., Mastroianni, C. M., Buzzetti, R., Ajassa, C., Alban, R., Alessi, F., Aronica, R., Belvisi, V., Candy, M., Caputi, A., Carrara, A., Casali, E., Cavallari, E. N., Ceccarelli, G., Celani, L., Ciardi, M. R., Coraggio, L., Curtolo, A., D'Agostino, C., D'Ettorre, G., De Giorgi, F., De Girolamo, G., Filippi, V., Gnessi, L., Luordi, C., Moretti, C., Recchia, G., Ridolfi, M., Romani, F. E., Russo, G., Ruberto, F., Savelloni, G., Siccardi, G., Siena, A., Sterpetti, S., Valeri, S., Vera, M., Volpicelli, L., Watanabe, M., Aiuti, M., Campagna, G., Del Borgo, C., Fondaco, L., Kertusha, B., Leonetti, F., Marocco, R., Masala, R., Zuccala, P., Nonnis, G., Rigoli, A., Strumia, A., and Alampi, D.

Subjects
lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, multimorbidity, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Pneumonia, Viral, pandemics, Logistic regression, metabolic diseases, law.invention, coronavirus infections, male, law, Diabetes mellitus, Internal medicine, middle aged, medicine, 80 and over, copd, covid-19, diabetes, hypertension, sars-cov-2, aged, cardiovascular diseases, diabetes mellitus, female, follow-up studies, humans, pneumonia, viral, prognosis, retrospective studies, risk factors, betacoronavirus, COPD, Original Investigation, Aged, 80 and over, Mechanical ventilation, business.industry, SARS-CoV-2, Confounding, Diabetes, Retrospective cohort study, Odds ratio, medicine.disease, Intensive care unit, lcsh:RC666-701, Hypertension, Cardiology and Cardiovascular Medicine, business, Covid-19
Abstract

Background Cardiometabolic disorders may worsen Covid-19 outcomes. We investigated features and Covid-19 outcomes for patients with or without diabetes, and with or without cardiometabolic multimorbidity. Methods We collected and compared data retrospectively from patients hospitalized for Covid-19 with and without diabetes, and with and without cardiometabolic multimorbidity (defined as ≥ two of three risk factors of diabetes, hypertension or dyslipidaemia). Multivariate logistic regression was used to assess the risk of the primary composite outcome (any of mechanical ventilation, admission to an intensive care unit [ICU] or death) in patients with diabetes and in those with cardiometabolic multimorbidity, adjusting for confounders. Results Of 354 patients enrolled, those with diabetes (n = 81), compared with those without diabetes (n = 273), had characteristics associated with the primary composite outcome that included older age, higher prevalence of hypertension and chronic obstructive pulmonary disease (COPD), higher levels of inflammatory markers and a lower PaO2/FIO2 ratio. The risk of the primary composite outcome in the 277 patients who completed the study as of May 15th, 2020, was higher in those with diabetes (Adjusted Odds Ratio (adjOR) 2.04, 95%CI 1.12–3.73, p = 0.020), hypertension (adjOR 2.31, 95%CI: 1.37–3.92, p = 0.002) and COPD (adjOR 2.67, 95%CI 1.23–5.80, p = 0.013). Patients with cardiometabolic multimorbidity were at higher risk compared to patients with no cardiometabolic conditions (adjOR 3.19 95%CI 1.61–6.34, p = 0.001). The risk for patients with a single cardiometabolic risk factor did not differ with that for patients with no cardiometabolic risk factors (adjOR 1.66, 0.90–3.06, adjp = 0.10). Conclusions Patients with diabetes hospitalized for Covid-19 present with high-risk features. They are at increased risk of adverse outcomes, likely because diabetes clusters with other cardiometabolic conditions.

Published
2020

24. Challenges in the Management of SARS-CoV2 Infection: The Role of Oral Bacteriotherapy as Complementary Therapeutic Strategy to Avoid the Progression of COVID-19

Author

d&apos, Ettorre, G., Ceccarelli, G., Marazzato, M., Campagna, G., Pinacchio, C., Alessandri, F., Ruberto, F., Rossi, G., Celani, L., Scagnolari, C., Mastropietro, C., Trinchieri, V., Recchia, G. E., Mauro, V., Antonelli, G., Pugliese, F., and Mastroianni, C. M.

Subjects
0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, bacteriotherapy, Disease, COVID-19, gut, gut-lung axis, lactobacillus, probiotic, SARS-CoV-2, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tocilizumab, Internal medicine, Oxygen therapy, Medicine, 030212 general & internal medicine, Original Research, lcsh:R5-920, business.industry, Hydroxychloroquine, General Medicine, Diarrhea, 030104 developmental biology, covid-19, sars-cov-2, Respiratory failure, chemistry, Concomitant, medicine.symptom, business, lcsh:Medicine (General), Bacteriotherapy, medicine.drug
Abstract

Background: Gastrointestinal disorders are frequent in COVID-19 and SARS-CoV-2 has been hypothesized to impact on host microbial flora and gut inflammation, infecting intestinal epithelial cells. Since there are currently no coded therapies or guidelines for treatment of COVID-19, this study aimed to evaluate the possible role of a specific oral bacteriotherapy as complementary therapeutic strategy to avoid the progression of COVID-19. Methods: We provide a report of 70 patients positive for COVID-19, hospitalized between March 9th and April 4th, 2020. All the patients had fever, required non-invasive oxygen therapy and presented a CT lung involvement on imaging more than 50%. Forty-two patients received hydroxychloroquine, antibiotics, and tocilizumab, alone or in combination. A second group of 28 subjects received the same therapy added with oral bacteriotherapy, using a multistrain formulation. Results: The two cohorts of patients were comparable for age, sex, laboratory values, concomitant pathologies, and the modality of oxygen support. Within 72 h, nearly all patients treated with bacteriotherapy showed remission of diarrhea and other symptoms as compared to less than half of the not supplemented group. The estimated risk of developing respiratory failure was eight-fold lower in patients receiving oral bacteriotherapy. Both the prevalence of patients transferred to ICU and mortality were higher among the patients not treated with oral bacteriotherapy. Conclusions: A specific bacterial formulation showed a significant ameliorating impact on the clinical conditions of patients positive for SARS-CoV-2 infection. These results also stress the importance of the gut-lung axis in controlling the COVID-19 disease.

Published
2020

34. Abstracts of posters

Author

Suffisseau L., Taugourdeau M. C., Goldstein F. W., Mainardi J. L., Larrouturou Ph., Romero, M., Cervino, A. R., Albertone, G., Di Pasquale, R., Venturini, F., Congedo, R., Benettolo, F., Pistolesi, C., Olivato, R., Casasin T., Agusti C., Gurrera M. T., Fabregas X., Rizo A., Badia J. M., Santa-Olalla M., Marini, P., Rampazzo, R., Scroccaro, G., Dell'Aera, M., Luzzi, R., Ciccarone, G., Martinet, N., Beney, J., Marty, S., Reymond, J. -Ph., Cairns, Chris, Morgutti M., Posco M., Moltempi M., Lonqhini P., Rossignoli A., Rihet, P., Carles, G., Braguer, D., Azulay, J. P., Pouget, J., Pelletier, J., Crevat, A., Past.o, L., Barroso, E., Pujol, R., Ferrer, I., Ibars, M., Llop, J. M., Frankfort, Ellen, van Dongen, Robert T. M., Hekster, Yechiel A., Kart, T., Rasmussen, M., Horn, A., Wested, L., Gagyi, O., Markó, E., Regazzi M. B., Martinelli L., Goggi C., Bellotti E., Molinaro M., Rinaldi M., Gavazzi A., Buggia I., Daneri A., Guarnone E., Bascapē V., Viganô M., Lazzaro, A., Palozzo, A., Banfi R., Borselli G., Fabbiani P., Marinai C., Delorme, J., Tubiana, N., Buck, M., Chinot, O., De Wever, C., Robays, H., Montoro J. B., Flores G., Juárez J. C., Juste C., Jardí R., Altisent C., Tusell J. M., Arpinelli, F., De Carli, G., Olivieri, A., Recchia, G., Rossignoli A., Longhini P., La Guidara C., Russo B., Moltempi M., Tamés, M. J., Cajaraville, G., Ponz, L., Echaniz, E., Garcia, B., van Mil, J. W. Foppe, Leufkens, Hubert G., v. Haelst, Ingrid M. M., Parel, Piet C. M., Scholten, Wim K., Sessink, F. G. M., Raschatt, R., Traversa, G., Donini, G., Arpino, C., Da Cas, R., Pasquin, P., Bernadotte af Wisborg G., Claesson C., Lundberg O., Thorslund M., Ferraro L., Marrazzo E., Ostino G., Tognoni G., Heerdink, Eibert R., Koppedraaijer, Corrie, Bakker, Albert, Bidoli E., Battistin M., Troncon M. G., Franceschi S., Serraino D., Marino, M., Matera, M. G., Berrino, L., Contaldi, C., Piucci, B., Rossi, F., Rolle C., Marrazzo E. 0., Murgia, V., Bussi, R., Schievano, P., Pedrini, A., Baraghini, M., Benini, A., Cataldo, M. M., Galletti, P., Magnani, M., Manzoli, M., Novi, M. V., Pezzi, O., Font M., Salmaso A. B., Mezzalira L., Braybrook, Saran, Walker, Roger, van Mil, J. W. F., Tromp, F. T. J., de Jong-v.d. Berg, L. T. W., Bakker, A., Paes, A. H. P., Soe-Agnie, C., Llopis, P., Tortajada, J. J., Font, I., Climente, M., Real, J. V., Almenar, D., Molins, C., Jiménez, N. V., Bellés Medall MD, Casterá Melchor DE, Marco Sena MA, Cantarinz Marti I., Abad Gimeno FJ, Török, J., Thurzó, L., Juárez J. C., Oliveras M., Hidalgo E., Cabañas M. J., Barroso C., Moraga F. A., Sánchez de Toledo J., Kollöffel, W. J., Driessen, F. G. W. H. M., Goldhoorn, P. B., Moral, M. A., Roglan, A., Mangues, M. A., Bonal, J., Clopés, A., Badell, I., Fraga, G., Deinum, J. T., van Lingen, R. A., Quak, J. M. E., Kuizenga, A. J., van Dam, J. G., Villani P., Maserati R., Viale P., Alberici F., Iacona I., Wasieczko, A., Szymura-Oleksiak, J., Wyska, E., Magulova, L., Sirotiakova, J., Letkovicova, M., Branger, E., Besse, D., Blin, O., Bille, F., Serratrice, G., Desnuelle, C., Grassin, J., Reben, I., Meunier, Ph., Antier, D., Berthet, M., Søndergaard B., Herborg H., Frøkjær B., Hepler C., Steckner, H., Bergold, A., Drings, P., Märkel, A., Manegold, C., Venning, Mary, Pazzagli, Luciana, Semmola, Maria Vittoria, Mannoni, Alessandro, Tersen I., Huchet J., Sevilla, E., Ferrari, J. M., Herreros de Tejada, A., Congedo, R., Font, M., Fraccaro, A., Osti, M., Pappagallo, G., Spolaor, A., Terrazzani, G., Vezzani, M., Edouard B., Laine G., Geeraerts D., Robays H., Carrera-Hueso, F. J., Font, B., Marquina, C., Idoate, A., Giráldez, J., Fernández, E., Lacasa, C., Guzzo, D., Martini, N., Boya, P. Giner, González, M. M. Negredo, Agulló, J. Muñoz, Mansilla, L. Lorente, Nahata, Milap C., Troncon, M. G., Cattaruzzi, C., Bilbao G., Galende I., Atañé C., Bermudez de Castro A., Delgado O., Escribano B., Frías J., Gabriel R., Gómez J. A., Gracia D., Gutiérrez E., Hellín T., Izquierdo J. L., Moreno A., Requena T., Sainz-Terreros M., Tejedor J. C., Torralba A., Vigil D., Scuffi, C., Trallori, G., Messori, A., Bardazzi, G., Bonanomi, A., Silvano, R., D'Albasio, G., Bardelli, F., Verona, Firenzee, Bardelli, F., Corrado, A., Ferriols R., Aleixander M. J., Garcia J., Faus M., Ibañez E., Alós M., Rinaldi, M., Pharmacy & Therapeutic Committee (Ps&TC), Collaborative Group, SIFO-Veneto Working Group on Clinical Trials, Working Group on the Elaboration of an Approval Conditions Document to certify the Clinical Trials Ethics Committees in the Autonomous Community of Madrid, and Area SIFO di Metanalisi

Published
1994
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36. Italian guidelines for therapy of atopic dermatitis—Adapted from consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis)

Author

Damiani, G, Calzavara-Pinton, P, Stingeni, L, Hansel, K, Cusano, F, Pigatto, P, Agostinelli, D, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Barbagallo, T, Belloni-Fortina, A, Berta, M, Biale, C, Bianchi, L, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Bragazzi, N, Brambilla, L, Bressan, M, Brunasso, A, Bruni, F, Bruni, P, Caccavalle, S, Calogiuri, G, Cannavo, S, Carugno, A, Cataldi, I, Chiarelli, G, Cirla, A, Corazza, M, Cossutta, M, Cova, L, Cristaudo, A, Danese, P, Dal Canton, M, Depita, O, De Salvo, P, Donini, M, Fantini, F, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalci, S, Frasin, L, Gallo, R, Gasparini, G, Gola, M, Gravante, M, Guarnieri, F, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Malara, G, Magrini, L, Marone, G, Martina, E, Mascagni, P, Chiari, M, Meligeni, L, Melino, M, Miccio, L, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Naldi, L, Napolitano, M, Nasca, M, Pacifico, A, Paganini, P, Papini, M, Pasolini, G, Patruno, C, Pellegrino, M, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Romita, P, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Tasin, L, Tramontana, M, Taddei, L, Valsecchi, R, Russo, F, Vascellaro, A, Venturini, M, Vincenzi, C, Virgili, A, Zucca, M, Pigatto, PDM, Arigliano, PL, Bragazzi, NL, Brunasso, AMG, Cannavo, SP, Cirla, AM, DePita, O, Ferrucci, SM, Flori, ML, Frasin, LA, Ingordo, V., Lauriola, MM, Chiari, Matteini M, Musumeci, ML, Nasca, MR, Raviolo, PD, Recchia, GP, Valsecchi, RE, Damiani, G, Calzavara-Pinton, P, Stingeni, L, Hansel, K, Cusano, F, Pigatto, P, Agostinelli, D, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Barbagallo, T, Belloni-Fortina, A, Berta, M, Biale, C, Bianchi, L, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Bragazzi, N, Brambilla, L, Bressan, M, Brunasso, A, Bruni, F, Bruni, P, Caccavalle, S, Calogiuri, G, Cannavo, S, Carugno, A, Cataldi, I, Chiarelli, G, Cirla, A, Corazza, M, Cossutta, M, Cova, L, Cristaudo, A, Danese, P, Dal Canton, M, Depita, O, De Salvo, P, Donini, M, Fantini, F, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalci, S, Frasin, L, Gallo, R, Gasparini, G, Gola, M, Gravante, M, Guarnieri, F, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Malara, G, Magrini, L, Marone, G, Martina, E, Mascagni, P, Chiari, M, Meligeni, L, Melino, M, Miccio, L, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Naldi, L, Napolitano, M, Nasca, M, Pacifico, A, Paganini, P, Papini, M, Pasolini, G, Patruno, C, Pellegrino, M, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Romita, P, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Tasin, L, Tramontana, M, Taddei, L, Valsecchi, R, Russo, F, Vascellaro, A, Venturini, M, Vincenzi, C, Virgili, A, Zucca, M, Pigatto, PDM, Arigliano, PL, Bragazzi, NL, Brunasso, AMG, Cannavo, SP, Cirla, AM, DePita, O, Ferrucci, SM, Flori, ML, Frasin, LA, Ingordo, V., Lauriola, MM, Chiari, Matteini M, Musumeci, ML, Nasca, MR, Raviolo, PD, Recchia, GP, and Valsecchi, RE

Abstract

Atopic dermatitis (AD) therapeutic approach calls for a long-term treatment. Treatment options for AD have recently undergone a revolutionary change by the introduction of the first biologic drug. Availability in daily practice of the last version of international AD guidelines, taking peculiarities of the country into account, can contribute to good clinical practice in Italy. To adapt European Dermatology Forum (EDF) guidelines for AD to the Italian medical–legal context, the EDF guidelines were assessed independently by two independent Italian renowned experts in the field and further integrated with articles published and systematically reviewed before May 2019. The first draft was collegially corrected and updated by the members of the SIDEMAST, ADOI, and SIDAPA. Recommendation levels (A; B; C; D) were graded based on the evidence levels (1–4). The adapted guidelines presented here focus on topical and systemic therapies in AD patients, both children and adults. As opposed to previous Italian guidelines, they include indications about biologics. New relevant evidence available from very recent literature and peculiarities of the Italian medical and legal context have been integrated in the revision process. If compared to general guidelines for AD not adapted to a specific national and cultural context, a revision for specific Italian needs is now available: It comprises the option of implementing the new biologic treatments and is likely to provide an important contribution to the improvement of clinical practice in Italy. Cooperation between patients, dermatologists, allergologists, and pediatricians remains mandatory in AD management. The authors of the present revision recommend an update of the Italian guidelines to be performed at least every second year.

Published
2019

44. The Cetina phenomenon across the Adriatic during the 2nd half of the 3rd millennium BC: new data and research perspectives

Author

Gori, M., Recchia, G., Tomas, H., and Gravina, Armando

Subjects
adriatic, early bronze age, cross-cultural interactions, cetina, Cetina-type pottery, Cettina phenomenon
Abstract

What is now termed the ‘Cetina phenomenon’ has recently received renewed scholarly attention, as a result of new discoveries and reappraisals of already known evidence in Croatia, Italy, Greece and Malta. In this paper we will concisely discuss new data from Dalmatia, with particular emphasis on the area between Šibenik and Split, which is the core area of the Cetina culture, and from southern Italy. Finally, we will briefly present our current research projects and the preliminary results these have provided.

Published
2018

47. Ceramiche egee e di tipo egeo da Coppa Nevigata (FG). Nuovi documenti

Author

Bettelli M, Recchia G, and Vagnetti L

Subjects
bronze age, interrelazioni, Egeo, età del Bronzo, aegean-type pottery, coppa nevigata, Italia
Abstract

Presentazione di nuovi dati sulle ceramiche egee dal sito dell'età del Bronzo di Coppa Nevigata (FG)

Published
2017

48. Monitoring Large Railways Infrastructures Using Hybrid Fbg/Raman Sensor Systems

Author

Velha, P., primary, Nannipieri, T., additional, Signorini, A., additional, Morosi, M., additional, Solazzi, M., additional, Barone, F., additional, Frisoli, A., additional, Ricciardi, L., additional, Giuliani, S., additional, Eusepi, R., additional, Icardi, M., additional, Recchia, G., additional, Lupi, M., additional, Arcoleo, G., additional, Firmi, P., additional, and Di Pasquale, F., additional

Published
2018
Full Text
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