Search

Jamestown Canyon virus disease (JCVD) is a potentially neuroinvasive condition caused by the arbovirus Jamestown Canyon virus (JCV). Human cases of JCVD have increased in New Hampshire (NH) over the past decade, but vector surveillance is limited by funding and person power. We conducted mosquito surveillance with a focus on human JCVD cases south central NH during 2021. Routine surveillance with CDC miniature traps baited with CO2 (lights removed) was supplemented by a paired trapping design to test the collection efficiency of octenol, and New Jersey light traps. We performed virus testing, blood meal analysis, and compared morphological identification with DNA barcoding. Over 50,000 mosquitoes were collected representing 28 species. Twelve JCV-positive pools were derived from 6 species of more than 1,600 pools tested. Of those, Aedes excrucians/stimulans (MLE 4.95, Diptera: Culicidae, Walker, 1856, 1848), and Aedes sticticus (MLE 2.02, Meigen, 1838) had the highest JCV infection rates, and Aedes canadensis (MLE 0.13, Theobold, 1901) and Coquillettidia perturbans (0.10, Diptera: Culicidae, Walker, 1856) had the lowest infection rates. One hundred and fifty-one blood meals were matched to a vertebrate host. All putative vectors fed on the amplifying host of JCV, white-tailed deer (36–100% of bloodmeals). Putative vectors that fed on human hosts included Aedes excrucians (8%), Anopheles punctipennis (25%, Diptera: Culicidae, Say, 1823), and Coquillettidia perturbans (51%). CDC traps baited with CO2 were effective for collecting putative vectors. DNA barcoding enhanced morphological identifications of damaged specimens. We present the first ecological overview of JCV vectors in NH.

In an epoch of rapid environmental change, understanding and predicting how biodiversity will respond to a changing climate is one of the most urgent challenges faced in ecology and evolution. Since we seldom have sufficient long-term biological data to use the past to anticipate the future, spatial climate-biotic associations are often used as a proxy for predicting biotic responses to climate change over time. These ‘space-for-time substitutions’ (SFTS) have become near ubiquitous in global change biology, but with different subfields having largely developed in isolation. We review how climate-focussed SFTS are used in four subfields of global change biology, each focussed on a different response type – population phenotypes, population genotypes, species’ distributions, and ecological communities. We identify the similarities and differences between the methods, the limitations and opportunities within each subfield, and highlight the potential for different subfields to gain insight from each other. While SFTS are used for a wide range of applications, two main approaches are applied across subfields: in situ gradient methods (including ecological niche modelling) and transplants (common gardens and reciprocal transplants). All SFTS methods and applications share a number of key limitations and assumptions relating to (i) the causality of identified spatial associations and (ii) the transferability of these relationships over time. Despite their widespread use, key assumptions in SFTS remain largely untested, including the fundamental assumption that climate-biotic relationships observed over space are causal and are equivalent to those occurring over time. We highlight how the robustness of SFTS can be improved by addressing these assumptions and limitations, with a particular emphasis on where approaches could be shared between subfields.

Our previous work identified that nine leading guidance documents for seven different types of systematic review advocated the same process of literature searching. We defined and illustrated this process and we named it ‘the Conventional Approach’. The Conventional Approach appears to meet the needs of researchers undertaking literature searches for systematic reviews of clinical interventions. In this article, we report a new and alternate process model of literature searching called ‘A Tailored Approach’. A Tailored Approach is indicated as a search process for complex reviews which do not focus on the evaluation of clinical interventions. The aims of this article are to (1) explain the rationale for, and the theories behind, the design of A Tailored Approach; (2) report the current conceptual illustration of A Tailored Approach and to describe a user’s interaction with the process model; and (3) situate the elements novel to A Tailored Approach (when compared with the Conventional Approach) in the relevant literature. A Tailored Approach suggests investing time at the start of a review, to develop the information needs from the research objectives, and to tailor the search approach to studies or data. Tailored Approaches should be led by the information specialist (librarian) but developed by the research team. The aim is not necessarily to focus on comprehensive retrieval. Further research is indicated to evaluate the use of supplementary search methods, methods of team-working to define search approaches, and to evaluate the use of conceptual models of information retrieval for testing and evaluation.

The use of non‐medical referral, community referral or social prescribing interventions has been proposed as a cost‐effective alternative to help those with long‐term conditions manage their illness and improve health and well‐being. However, the evidence base for social prescribing currently lags considerably behind practice. In this paper, we explore what is known about whether different methods of social prescribing referral and supported uptake do (or do not) work. Supported by an Expert Advisory Group, we conducted a realist review in two phases. The first identified evidence specifically relating to social prescribing in order to develop programme theories in the form of ‘if‐then’ statements, articulating how social prescribing models are expected to work. In the second phase, we aimed to clarify these processes and include broader evidence to better explain the proposed mechanisms. The first phase resulted in 109 studies contributing to the synthesis, and the second phase 34. We generated 40 statements relating to organising principles of how the referral takes place (Enrolment), is accepted (Engagement), and completing an activity (Adherence). Six of these statements were prioritised using web‐based nominal group technique by our Expert Group. Studies indicate that patients are more likely to enrol if they believe the social prescription will be of benefit, the referral is presented in an acceptable way that matches their needs and expectations, and concerns elicited and addressed appropriately by the referrer. Patients are more likely to engage if the activity is both accessible and transit to the first session supported. Adherence to activity programmes can be impacted through having an activity leader who is skilled and knowledgeable or through changes in the patient's conditions or symptoms. However, the evidence base is not sufficiently developed methodologically for us to make any general inferences about effectiveness of particular models or approaches.

This handbook is about how Nature on Prescription can be used to support people’s mental health, and makes evidence-based suggestions for how to develop and implement a high-quality scheme, in the new social prescribing landscape. The handbook is primarily aimed at nature-based providers of group nature-based interventions that target common mental health conditions, and that are (or will be) delivered via social prescribing schemes. The content will also be of interest to link workers, general practitioners, mental health practitioners, and researchers with an interest in social prescribing. The content is intended to assist development of interventions that are beneficial, safe, and sustainable. We hope this handbook may: help avoid pitfalls that may lead to Nature on Prescription failing to support people appropriately; make the most of programmes from the earliest stages; help reach desired outcomes for both organisations and participants; and help in designing appropriate evaluations. In this handbook we draw on research evidence and learnings from past and ongoing nature-based interventions, and from other relevant fields. There is a wealth of experience from people who have been involved in delivery of nature-based interventions in the UK. The content of the handbook is also informed by interviews carried out with these individuals and other relevant stakeholders.

IntroductionGreen and blue spaces (GBS), such as parks, woodlands, rivers, and beaches, are thought to be important for mental health and wellbeing. Our longitudinal cohort contains objective household-level environment data linked at the invidual level to routinely recorded mental health data, augmented with cross sectional self-reported health behaviours, including leisure visits to the outdoors. Objectives and ApproachOur overall approach will evaluate if residential proximity to GBS is associated with mental health and wellbeing, and if any associations aremodified by visits to outdoors spaces following individual-level data linkage. Here, we examined cross-sectional survey data on time spent visiting nature outdoors. Wellbeing outcomes were assessed using self-reported scores. Data were analysed using generalised additive models in the SAIL Databank. ResultsUsing a sample of National Survey for Wales respondents (2016/17, n=3,481), over 40% of adults in Wales reported spending less than 30 minutes outdoors each week. Weekly time outdoors was positively associated with wellbeing (p=0.007) and life satisfaction (p=0.03) having adjusted for potential confounders including, age, rurality, loneliness, employment status. Confidence intervals varied along the fitted GAM model. Models using a second wave of survey data (n≈7,000), anonymously record-linked to residential environment and health data will explore these associations further. ConclusionA previous study based in England (White et al. 2019) found an upper wellbeing benefit threshold of 2 hours per week for time spent in nature. This was not apparent in our preliminary models, but may be revealed in further analyses. We will next incorporate longitudinal mental health and environmental data for 2 million adults living in Wales, UK. Linking to ambient and accessible residential GBS, while taking into account changes due to migration and actual visits, will allow us to provide valuable guidance to local government, who are often responsible for provisioning and maintaining outdoor facilities.

IntroductionA growing evidence base indicates health benefits are associated with access to green-blue spaces (GBS), such as beaches and parks. However, few studies have examined associations with changes in access to GBS over time. Objectives and ApproachWe have linked cross-sector data collected within Wales, United Kingdom, quarterly from 2008 to 2019, to examine the impact of GBS access on individual-level well-being and common mental health disorders (CMD). We created a longitudinal dataset of GBS access metrics, derived from satellite and administrative data sources, for 1.4 million homes in Wales. These household-level metrics were linked to individuals using the Welsh Demographic Service Dataset within the Secure Anonymised Information Linkage (SAIL) Databank. Linkage to Welsh Longitudinal General Practice data within SAIL enabled us to identify individual-level CMD over time. We also linked individual-level self-reported GBS use and well-being data from the National Survey for Wales (NSW) to routine data for cross-sectional survey participants. ResultsWe created a longitudinal cohort panel capturing all 2.84 million adults aged 16+ living in Wales between 2008 and 2019 and with a general practitioner (GP) registration. Individual-level health data and household-level environmental metrics were linked for each quarter an individual is in the study. Household addresses were linked to 97% of the cohort, creating 110+ million rows of anonymously linked cross-sector data. The cohort provides an average follow-up period of 8 years, during which 565,168 (20%) adults received at least one CMD diagnosis or symptom. Conclusion / ImplicationsThis example of multi-sectoral data linkage across multiple environmental and administrative data sources has created a rich data source, which we will use toquantify the impact of changes in GBS access on individual–level CMD and well-being. This evidence will inform policy in the areas of health, planning and the environment.

Current evidence suggests that biodiverse environmental microbiomes contribute positively to human health and could account for known associations between urban green space and improved health. We ...

Background Evidence that greenspaces are related to mental health and wellbeing mostly relies on residential exposure and few studies have considered actual use. We aimed to link the National Survey for Wales (NSW) to environmental metrics to determine whether there is an association between increased residential exposure to greenspace and subjective wellbeing, and whether this is mediated by visits to outdoor spaces. Methods In this cross-sectional data linkage study, we linked NSW data (2016–17 and 2018–19; repeat cross-sectional) to the Secure Anonymised Information Linkage (SAIL) Databank. Survey data included the Warwick and Edinburgh Mental Wellbeing Scale (WEMWBS), and self-reported time spent on leisure visits to open spaces in Wales (including bluespaces; derived from visit frequency in the past 4 weeks and duration of the main activity on the most recent visit). Linkage at individual level augmented this data with home neighbourhood greenspace data (Enhanced Vegetation Index [EVI] derived from satellite imagery). Using multivariate linear regression models, we estimated associations between home or visit exposures and WEMWBS, adjusting for various covariates including area level (via Welsh Index of Multiple Deprivation) and individual deprivation indicators. EVI, weekly time outdoors, and WEMWBS were standardised and both linear and quadratic terms were included in analyses. The e-cohort uses anonymised data and was approved by the SAIL Information Governance Review Panel. Findings Among NSW respondents providing outcome measures (n=5971), EVI was significantly related to both WEMWBS (U-shaped relationship, EVI beta −0·02, p=0·13; EVI2 beta 0·02, p= 0·0098), and weekly time outdoors (EVI beta 0·04, p=0·020). Time outdoors was also significantly related to WEMWBS (time outdoors beta 0·17, p Interpretation Living near and time spent visiting greenspaces and bluespaces were both related to better subjective wellbeing. The absence of mediation suggests that better wellbeing associated with EVI occurs through a different mechanism than visiting. Funding National Institute for Health Research.

Although the (perceived) biodiversity of a natural environment can influence people's actual, or predicted, restorative experiences, little is known about the generality of these effects or the importance of other aspects such as wildlife behaviour. The current research used an experimental approach (with photographs and videos of coastal scenes) to investigate these issues among a large heterogeneous UK sample (n=1,478). On average, coastal settings with higher perceived biodiversity were rated as offering greater restorative potential and were associated with higher willingness-to-visit. Men, and people with lower overall ratings, tended to be more sensitive to biodiversity levels, and older respondents believed coastal settings in general offered more restorative potential. Locations where a species was exhibiting High vs. Low fascination behaviours (e.g. murmurating vs. sleeping) were also rated more positively, highlighting the importance of wildlife behaviour on psychological outcomes, in addition to biodiversity. Implications for conservation and communication are discussed.

A broad and growing evidence base suggests the potential for time spent in natural environments to promote human health and well-being. Whilst evidence of such benefits is rapidly accumulating, we still know relatively little about the role of wildlife encounters in shaping the well-being potential of people’s routine green/blue space interactions, particularly amongst non-specialists. This article addresses this conceptual gap, drawing on the findings of a three-stage, qualitative, interpretive study which sought to understand and situate people’s natural environment well-being experiences within their everyday lives. Wildlife encounters were emphasised by study participants in the context of four types of well-being experience: social, immersive, symbolic and achievement oriented. These are explored within this paper, before discussing the influence of past experiences and current life circumstances on participants’ wildlife relationships. Consideration is also given to how environmental manager...

Health is not equally distributed across society; there are avoidable, unfair, systematic differences in health between population groups. Some of these same groups (older people, BAME communities, those with some non-communicable diseases (NCDs)) may be particularly vulnerable to risk of exposure and severe COVID-19 outcomes due to co-morbidities, structural vulnerabilities, and public-facing or health and social care jobs among other factors. Additionally, some of the restrictions designed to reduce SARS-CoV-2 spread impact specifically on these same groups by limiting their activity and access to preventive or health promotion services. Greenspaces, accessed with social distancing, may mitigate some of the predicted negative health effects of COVID-19 restrictions. Maintaining or increasing publicly accessible urban greenspaces, particularly for marginalised groups, is reflected in the Sustainable Development Goals, and its importance amplified in the COVID-19 pandemic. Urban greenspaces should be considered a public health and social investment and a chance to rebalance our relationship with nature to protect against future pandemics. By investing in urban public greenspaces, additional benefits (job/food creation, biodiversity promotion, carbon sequestration) may coincide with health benefits. Realising these requires a shift in the balance of decision making to place weight on protecting, enhancing and providing more appropriate greenspaces designed with local communities. The current pandemic is a reminder that humanity placing too many pressures on nature has damaging consequences. COVID-19 economic recovery programs present an opportunity for sustainable transformation if they can be leveraged to simultaneously protect and restore nature and tackle climate change and health inequalities.

The paper problematises the reliability and ethics of using social media data, such as sourced from Twitter or Instagram, to carry out health-related research. As in many other domains, the opportunity to mine social media for information has been hailed as transformative for research on well-being and disease. Considerations around the fairness, responsibilities and accountabilities relating to using such data have often been set aside, on the understanding that as long as data were anonymised, no real ethical or scientific issue would arise. We first counter this perception by emphasising that the use of social media data in health research can yield problematic and unethical results. We then provide a conceptualisation of methodological data fairness that can complement data management principles such as FAIR by enhancing the actionability of social media data for future research. We highlight the forms that methodological data fairness can take at different stages of the research process and identify practical steps through which researchers can ensure that their practices and outcomes are scientifically sound as well as fair to society at large. We conclude that making research data fair as well as FAIR is inextricably linked to concerns around the adequacy of data practices. The failure to act on those concerns raises serious ethical, methodological and epistemic issues with the knowledge and evidence that are being produced.

Research has found that natural environments within urban areas are associated with benefits for human health and wellbeing. However, most studies have primarily focused on publically accessible green space. Less is known about domestic gardens, which in the UK comprise a high proportion of land cover in urban areas and could form a resource for health promotion. This study analysed secondary data from the Monitor of Engagement with the Natural Environment (MENE) survey, a representative survey of the English population (n = 7,814). We investigated the relationships between garden access and use and: general health; evaluative and eudaimonic wellbeing; meeting physical activity guidelines; and visiting nature in the last week. Statistical models included a range of individual and area-level socio-demographic variables. Compared to no garden access, access to a private garden was associated with better evaluative wellbeing, and people with access to a private space such as a balcony, yard or patio were more likely to meet physical activity guidelines. Respondents who reported both gardening and using a garden to relax also reported better health and wellbeing, more physical activity, and more nature visits than those who did not. These findings indicate that domestic gardens are a potential health resource and are not necessarily substituted for by other natural environments, highlighting the importance of their provision alongside green space in urban policy and planning.

Imperforate hymen is a rare congenital malformation that usually presents in adolescence with primary amenorrhoea and pain or pressure-related symptoms from haematocolpos. We present the case of an 11- year-old girl who presented as a surgical emergency with acute abdominal pain. A laparoscopy was performed for suspected appendicitis, but she was subsequently found to have a haematocolpos secondary to imperforate hymen. This case illustrates the challenges in making the diagnosis. The literature contains numerous cases where the diagnosis has been delayed, and we discuss those that also presented as possible appendicitis. These cases highlight the importance of awareness of the condition amongst general surgeons and emergency physicians, and the role of external genital examination and ultrasonography prior to surgical intervention.

Although aquatic (blue) landscapes have been used to promote health for centuries, systematic research to explore these issues is relatively recent. We identify four strands of evidence, using different methodological approaches. Preference-based approaches use revealed (e.g. house prices), and stated (e.g. willingness to visit) preferences to examine people’s choice behaviours and intentions in relation to blue landscapes. Experiential approaches tap into people’s experiences in and around blue landscapes (e.g. during and after visits). Experimental approaches deconstruct blue landscapes and explore their impact under controlled conditions, in particular in comparison with the impacts of other landscape types. Finally, quantitative spatial approaches use epidemiological methods to explore health and well-being in relation to how close individuals live to aquatic environments. Broadly speaking, all four approaches suggest important potential for health benefits from blue landscapes, though important caveats, such as the quality of the blue landscape, were also found.

Exposure to green space is associated with a variety of positive health states. Research to date has focused primarily on 'generic' green space in urban areas, where green space is relatively scarce and where it is dominated by playing fields and parks. The current research adds to our understanding with an examination of relationships between different types of green space and mental health in rural areas in England (approximate rural population = 4 million). The aggregate land cover classes of Land Cover Map 2007 were linked to rural residential areas (Lower-level Super Output Areas) and then linked to rural participants (n = 2020) in the 18-year longitudinal British Household Panel Survey. Random effects regression of mental health (as measured by GHQ12 scores) against land cover enabled effects to be simultaneously estimated from both mean between-individual differences and from within-individual differences over time. The nine natural land cover classes (Broadleaved woodland; Coniferous woodland; Arable; Improved grassland; Semi-natural grassland; Mountain, heath and bog; Saltwater; Freshwater; Coastal) were not significantly associated with differences in mental health between individuals. However, significant relationships were observed between some types of land cover and within-individual change in mental health amongst individuals who relocated during the 18 annual waves of the panel. These findings indicate the presence of important health related ecosystem services from different land cover types that have not previously been investigated and which help more effective spatial planning and land use management. (C) 2015 Elsevier B.V. All rights reserved.

This methods paper contributes to the recent proliferation of methodological innovation aimed at nurturing research encounters and exchanges that facilitate in-depth insights into people's everyday practices and routine place encounters. By drawing on the experiences of an interpretive study seeking to situate people's green space wellbeing practices within their daily lives, we suggest value in using personalised maps – produced using participant accelerometer (physical activity) and Global Positioning System (GPS) data – alongside in-depth and mobile ‘go-along’ qualitative interview approaches. After introducing the study and the methods adopted, the paper discusses three opportunities offered by this mixed method approach to contribute a more nuanced, contextualised understanding of participants' green space experiences. These include: (a) the benefits of engaging participants in the interpretation of their own practices; (b) the value of using maps to provide a visual aid to discussion about the importance of participants' routine, often pre-reflective practices; and (c) the production of a layered appreciation of participants' local green and blue space wellbeing experiences. Used in combination, such methods have the potential to provide a more comprehensive picture of how current green space experiences, be they infrequent and meaningful, or more routine and habitual, are shaped by everyday individual agency, life circumstances and past place experiences.

BACKGROUND: We undertook a systematic review to evaluate the health benefits of environmental enhancement and conservation activities. We were concerned that a conventional process of study identification, focusing on exhaustive searches of bibliographic databases as the primary search method, would be ineffective, offering limited value. The focus of this study is comparing study identification methods. We compare (1) an approach led by searches of bibliographic databases with (2) an approach led by supplementary search methods. We retrospectively assessed the effectiveness and value of both approaches. METHODS: Effectiveness was determined by comparing (1) the total number of studies identified and screened and (2) the number of includable studies uniquely identified by each approach. Value was determined by comparing included study quality and by using qualitative sensitivity analysis to explore the contribution of studies to the synthesis. RESULTS: The bibliographic databases approach identified 21 409 studies to screen and 2 included qualitative studies were uniquely identified. Study quality was moderate, and contribution to the synthesis was minimal. The supplementary search approach identified 453 studies to screen and 9 included studies were uniquely identified. Four quantitative studies were poor quality but made a substantive contribution to the synthesis; 5 studies were qualitative: 3 studies were good quality, one was moderate quality, and 1 study was excluded from the synthesis due to poor quality. All 4 included qualitative studies made significant contributions to the synthesis. CONCLUSIONS: This case study found value in aligning primary methods of study identification to maximise location of relevant evidence.

Engagement with nature is an important part of many people&rsquo, s lives, and the health and wellbeing benefits of nature&ndash, based activities are becoming increasingly recognised across disciplines from city planning to medicine. Despite this, urbanisation, challenges of modern life and environmental degradation are leading to a reduction in both the quantity and the quality of nature experiences. Nature&ndash, based health interventions (NBIs) can facilitate behavioural change through a somewhat structured promotion of nature&ndash, based experiences and, in doing so, promote improved physical, mental and social health and wellbeing. We conducted a Delphi expert elicitation process with 19 experts from seven countries (all named authors on this paper) to identify the different forms that such interventions take, the potential health outcomes and the target beneficiaries. In total, 27 NBIs were identified, aiming to prevent illness, promote wellbeing and treat specific physical, mental or social health and wellbeing conditions. These interventions were broadly categorized into those that change the environment in which people live, work, learn, recreate or heal (for example, the provision of gardens in hospitals or parks in cities) and those that change behaviour (for example, engaging people through organized programmes or other activities). We also noted the range of factors (such as socioeconomic variation) that will inevitably influence the extent to which these interventions succeed. We conclude with a call for research to identify the drivers influencing the effectiveness of NBIs in enhancing health and wellbeing.

Background There is growing research and policy interest in the potential for using the natural environment to enhance human health and well-being. This resource may be underused as a health promotion tool to address the increasing burden of common health problems such as increased chronic diseases and mental health concerns. Outdoor environmental enhancement and conservation activities (EECA) (for instance unpaid litter picking, tree planting or path maintenance) offer opportunities for physical activity alongside greater connectedness with local environments, enhanced social connections within communities and improved self-esteem through activities that improve the locality which may, in turn, further improve well-being. Objectives To assess the health and well-being impacts on adults following participation in environmental enhancement and conservation activities. Search methods We contacted or searched the websites of more than 250 EECA organisations to identify grey literature. Resource limitations meant the majority of the websites were from UK, USA, Canada and Australia. We searched the following databases (initially in October 2012, updated October 2014, except CAB Direct, OpenGrey, SPORTDiscus, and TRIP Database), using a search strategy developed with our project advisory groups (predominantly leaders of EECA-type activities and methodological experts): ASSIA; BIOSIS; British Education Index; British Nursing Index; CAB Abstracts; Campbell Collaboration; Cochrane Public Health Specialized Register; DOPHER; EMBASE; ERIC; Global Health; GreenFILE; HMIC; MEDLINE-in-Process; MEDLINE; OpenGrey; PsychINFO; Social Policy and Practice; SPORTDiscus; TRoPHI; Social Services Abstracts; Sociological Abstracts; The Cochrane Library; TRIP database; and Web of Science. Citation and related article chasing was used. Searches were limited to studies in English published after 1990. Selection criteria Two review authors independently screened studies. Included studies examined the impact of EECA on adult health and well-being. Eligible interventions needed to include each of the following: intended to improve the outdoor natural or built environment at either a local or wider level; took place in urban or rural locations in any country; involved active participation; and were NOT experienced through paid employment. We included quantitative and qualitative research. Includable quantitative study designs were: randomised controlled trials (RCTs), cluster RCTs, quasi-RCTs, cluster quasi-RCTs, controlled before-and-after studies, interrupted-time-series, cohort studies (prospective or retrospective), case-control studies and uncontrolled before-and-after studies (uBA). We included qualitative research if it used recognised qualitative methods of data collection and analysis. Data collection and analysis One reviewer extracted data, and another reviewer checked the data. Two review authors independently appraised study quality using the Effective Public Health Practice Project tool (for quantitative studies) or Wallace criteria (for qualitative studies). Heterogeneity of outcome measures and poor reporting of intervention specifics prevented meta-analysis so we synthesised the results narratively. We synthesised qualitative research findings using thematic analysis. Main results Database searches identified 21,420 records, with 21,304 excluded at title/abstract. Grey literature searches identified 211 records. We screened 327 full-text articles from which we included 21 studies (reported in 28 publications): two case-studies (which were not included in the synthesis due to inadequate robustness), one case-control, one retrospective cohort, five uBA, three mixed-method (uBA, qualitative), and nine qualitative studies. The 19 studies included in the synthesis detailed the impacts to a total of 3,603 participants: 647 from quantitative intervention studies and 2630 from a retrospective cohort study; and 326 from qualitative studies (one not reporting sample size). Included studies shared the key elements of EECA defined above, but the range of activities varied considerably. Quantitative evaluation methods were heterogeneous. The designs or reporting of quantitative studies, or both, were rated as ‘weak’ quality with high risk of bias due to one or more of the following: inadequate study design, intervention detail, participant selection, outcome reporting and blinding. Participants’ characteristics were poorly reported; eight studies did not report gender or age and none reported socio-economic status. Three quantitative studies reported that participants were referred through health or social services, or due to mental ill health (five quantitative studies), however participants' engagement routes were often not clear. Whilst the majority of quantitative studies (n = 8) reported no effect on one or more outcomes, positive effects were reported in six quantitative studies relating to short-term physiological, mental/emotional health, and quality-of-life outcomes. Negative effects were reported in two quantitative studies; one study reported higher levels of anxiety amongst participants, another reported increased mental health stress. The design or reporting, or both, of the qualitative studies was rated as good in three studies or poor in nine; mainly due to missing detail about participants, methods and interventions. Included qualitative evidence provided rich data about the experience of participation. Thematic analysis identified eight themes supported by at least one good quality study, regarding participants' positive experiences and related to personal/social identity, physical activity, developing knowledge, spirituality, benefits of place, personal achievement, psychological benefits and social contact. There was one report of negative experiences. Authors' conclusions There is little quantitative evidence of positive or negative health and well-being benefits from participating in EECA. However, the qualitative research showed high levels of perceived benefit among participants. Quantitative evidence resulted from study designs with high risk of bias, qualitative evidence lacked reporting detail. The majority of included studies were programme evaluations, conducted internally or funded by the provider. The conceptual framework illustrates the range of interlinked mechanisms through which people believe they potentially achieve health and well-being benefits, such as opportunities for social contact. It also considers potential moderators and mediators of effect. One main finding of the review is the inherent difficulty associated with generating robust evidence of effectiveness for complex interventions. We developed the conceptual framework to illustrate how people believed they benefited. Investigating such mechanisms in a subsequent theory-led review might be one way of examining evidence of effect for these activities. The conceptual framework needs further refinement through linked reviews and more reliable evidence. Future research should use more robust study designs and report key intervention and participant detail.

Background School gardening programmes are increasingly popular, with suggested benefits including healthier eating and increased physical activity. Our objectives were to understand the health and well-being impacts of school gardens and the factors that help or hinder their success. Methods We conducted a systematic review of quantitative and qualitative evidence (PROSPERO CRD42014007181). We searched multiple databases and used a range of supplementary approaches. Studies about school gardens were included if they reported on physical or mental health or well-being. Quantitative studies had to include a comparison group. Studies were quality appraised using appropriate tools. Findings were narratively synthesised and the qualitative evidence used to produce a conceptual framework to illustrate how benefits might be accrued. Results Evidence from 40 articles (21 quantitative studies; 16 qualitative studies; 3 mixed methods studies) was included. Generally the quantitative research was poor. Evidence for changes in fruit and vegetable intake was limited and based on self-report. The qualitative research was better quality and ascribed a range of health and well-being impacts to school gardens, with some idealistic expectations for their impact in the long term. Groups of pupils who do not excel in classroom activities were thought to particularly benefit. Lack of funding and over reliance on volunteers were thought to threaten success, while involvement with local communities and integration of gardening activities into the school curriculum were thought to support success. Conclusion More robust quantitative research is needed to convincingly support the qualitative evidence suggesting wide ranging benefits from school gardens.

To determine whether height and body mass index (BMI) have a causal role in five measures of socioeconomic status.Mendelian randomisation study to test for causal effects of differences in stature and BMI on five measures of socioeconomic status. Mendelian randomisation exploits the fact that genotypes are randomly assigned at conception and thus not confounded by non-genetic factors.UK Biobank.119,669 men and women of British ancestry, aged between 37 and 73 years.Age completed full time education, degree level education, job class, annual household income, and Townsend deprivation index.In the UK Biobank study, shorter stature and higher BMI were observationally associated with several measures of lower socioeconomic status. The associations between shorter stature and lower socioeconomic status tended to be stronger in men, and the associations between higher BMI and lower socioeconomic status tended to be stronger in women. For example, a 1 standard deviation (SD) higher BMI was associated with a £210 (€276; $300; 95% confidence interval £84 to £420; P=6 × 10(-3)) lower annual household income in men and a £1890 (£1680 to £2100; P=6 × 10(-15)) lower annual household income in women. Genetic analysis provided evidence that these associations were partly causal. A genetically determined 1 SD (6.3 cm) taller stature caused a 0.06 (0.02 to 0.09) year older age of completing full time education (P=0.01), a 1.12 (1.07 to 1.18) times higher odds of working in a skilled profession (P=6 × 10(-7)), and a £1130 (£680 to £1580) higher annual household income (P=4 × 10(-8)). Associations were stronger in men. A genetically determined 1 SD higher BMI (4.6 kg/m(2)) caused a £2940 (£1680 to £4200; P=1 × 10(-5)) lower annual household income and a 0.10 (0.04 to 0.16) SD (P=0.001) higher level of deprivation in women only.These data support evidence that height and BMI play an important partial role in determining several aspects of a person's socioeconomic status, especially women's BMI for income and deprivation and men's height for education, income, and job class. These findings have important social and health implications, supporting evidence that overweight people, especially women, are at a disadvantage and that taller people, especially men, are at an advantage.

Recent research suggests coastal environments may promote human health and wellbeing. This article explores the diverse coastal experiences sought out by residents of two towns in south west England to promote and preserve their personal wellbeing in the context of their everyday lives. It draws on the findings of an in-depth interpretive study conducted from May to November 2013 that examined the relative contribution of varied green and blue space experiences to individual wellbeing through the life course. Personalised activity maps produced using accelerometer and Global Positioning System (GPS) data were used to guide in-depth geo-narrative interviews with a purposive sample of 33 participants. This was combined with a subset of nine case study go-along interviews in places deemed therapeutic by the participants themselves, offering deeper insight into the lived experiences and relationships playing out within such places. Situated in a novel adaptation of the therapeutic landscapes framework, this article explores how symbolic, achievement-oriented, immersive and social experiences contributed to participants' sense of wellbeing in their local coastal areas. Participants expressed particularly strong and often enduring connections to the local coastline, with different coastal stretches perceived to cater for varied therapeutic needs and interests, at multiple scales and intensities. The findings suggest the need for greater acknowledgement of people's emotional, deeply embodied and often shared connections to the coast within coastal management policy and practice, both nationally and internationally. Importantly, such efforts should recognise the fluid, dynamic nature of this land-sea boundary, and the valued therapeutic experiences linked to this fluidity.

BACKGROUND: Many studies suggest that exposure to natural environments ('greenspace') enhances human health and wellbeing. Benefits potentially arise via several mechanisms including stress reduction, opportunity and motivation for physical activity, and reduced air pollution exposure. However, the evidence is mixed and sometimes inconclusive. One explanation may be that "greenspace" is typically treated as a homogenous environment type. However, recent research has revealed that different types and qualities of natural environments may influence health and wellbeing to different extents.METHODS: This ecological study explores this issue further using data on land cover type, bird species richness, water quality and protected or designated status to create small-area environmental indicators across Great Britain. Associations between these indicators and age/sex standardised prevalence of both good and bad health from the 2011 Census were assessed using linear regression models. Models were adjusted for indicators of socio-economic deprivation and rurality, and also investigated effect modification by these contextual characteristics.RESULTS: Positive associations were observed between good health prevalence and the density of the greenspace types, "broadleaf woodland", "arable and horticulture", "improved grassland", "saltwater" and "coastal", after adjusting for potential confounders. Inverse associations with bad health prevalence were observed for the same greenspace types, with the exception of "saltwater". Land cover diversity and density of protected/designated areas were also associated with good and bad health in the predicted manner. Bird species richness (an indicator of local biodiversity) was only associated with good health prevalence. Surface water quality, an indicator of general local environmental condition, was associated with good and bad health prevalence contrary to the manner expected, with poorer water quality associated with better population health. Effect modification by income deprivation and urban/rural status was observed for several of the indicators.CONCLUSIONS: The findings indicate that the type, quality and context of 'greenspace' should be considered in the assessment of relationships between greenspace and human health and wellbeing. Opportunities exist to further integrate approaches from ecosystem services and public health perspectives to maximise opportunities to inform policies for health and environmental improvement and protection.

Background In social prescribing, people are referred by primary-care professionals to non-medical, community-based activities. The transfer between primary care and the community-based provider can be difficult, with low uptake and poor engagement with and adherence to interventions. There is an ambition to increase the use of social prescribing in the UK health service; however, to achieve this ambition the process of referral and retention needs improving. This study aimed to increase our understanding of what works and why in the social prescribing process and to apply this knowledge in primary-care settings where the use of the approach is being developed. Methods In a realist review of literature considering the process of social prescribing, bibliographic and grey literature searches were used to locate evidence. The relevance of the evidence was assessed and then used to develop theory. Findings were contextualised through focus groups in the partner primary-care setting. Findings Bibliographic and grey literature searches identified a total of 253 primary sources, and data were fully extracted from the most conceptually rich (n=109). Overarching programme theory integrating 40 active elements of the social prescribing process was developed through synthesis of the primary literature. This list was then refined through expert prioritisation leading to targeted searches conducted on key elements of the process relating to enrolment in, engagement with, and adherence to social prescribing. Key contexts and mechanisms contributing to successful uptake and enrolment included patient beliefs about suitable treatment options, presentation of the intervention and social prescribing process, accessibility of social prescribing (physically and psychologically), and supported uptake (eg, a link worker). Skilful and flexible intervention leadership and a change in the patient's condition were key contexts or mechanisms in maintaining adherence. Interpretation Use of a realist approach, with findings iteratively refined and applied in a primary-care setting, has facilitated a better understanding of what works in the social prescribing process. However, despite increasing interest in the approach, there is a paucity of information in the current evidence base about how social prescribing interventions are developed, offered, and delivered. Therefore, future social prescribing interventions should integrate process evaluations. Funding Part funded by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South West Peninsula at the Royal Devon and Exeter NHS Foundation Trust.

This essay examines the assumptions of green space use underpinning much existing green space and health research. It considers opportunities to move the field forward through exploring two often overlooked aspects of individual agency: the influence of shifting life circumstances on personal wellbeing priorities and place practices, and the role of personal orientations to nature in shaping how green space wellbeing opportunities are perceived and experienced. It suggests such efforts could provide more nuanced insights into the complex, personal factors that define and drive individual choices regarding the use of green spaces for wellbeing over time, thereby strengthening our understanding of the salutogenic potential (and limits) of green spaces.

Evidence for health and wellbeing benefits of exposure to natural environments is mixed; one possible explanation is that much of the research has treated nature generically as 'greenspace'. To exp...