110 results on '"Real N"'
Search Results
2. Quality indicators in interhospital transport: multicentre project
- Author
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Garrido B, Millán-García del Real N, Esclapes T, Marsinyach I, Toledo JD, Nuñez MM, Dominguez P, Brandstrup KB, Grp Trabajo Transporte Pediat, and Soc Espanola Cuidados Intensivos
- Subjects
Benchmarking ,Quality metrics ,Quality indicators ,Quality improvement ,Interhospital transport ,Quality assessment - Abstract
Introduction: Interhospital transport is carried out by variable teams in different regions of our country, and this makes quality evaluation and benchmarking complicated. Project objective: select and define a consensual list of quality measurement that may be used by national transport units, whether specialised or not. Methods: Initial set of quality indicators was proposed by coordinators (members of representative specialised transport units in Spain). Evaluation by selected transport specialists from participating units and SECIP (Society of Paediatric Intensive Care) and SENeo (Spanish Neonatology Society) work teams. Selection of definitive indicators by Delphi method according to relevance and feasibility. Results: A total of 35 quality indicators were included in the initial set. Evaluation was carried out by 22 specialists from seven transport teams. In a first round, four indicators were consensually included in the definitive list. Results for the rest of metrics and comments were sent to all participants, and after a second assessment, 11 other indicators reached enough consensus. After list accomplishment, a consensual final definition for every indicator was established. Conclusions: Using a consensual research method, a list of 15 common indicators was obtained, which may be used by specialised transport teams in our country, and by non-specialised clinics in charge of interhospital paediatric transport. It will allow individual performance to be assessed, as well as benchmarking, in order to find improvement opportunities and ensure the highest quality during interhospital transport. (C) 2020 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U.
- Published
- 2021
3. O ensino da responsabilidade pessoal e social no contexto extracurricular: uma revisão sistemática
- Author
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Baptista, C., Corte-Real, N., Regueiras, L., Seo, G., Hemphill, M., Pereira, A., Dias, C., Martinek, T., and Fonseca, A.
- Subjects
Modelo de responsabilidad ,extracurricular ,after-school ,physical activity ,Modelo de responsabilidade ,atividade física ,actividad física ,TPSR Alliance ,Teaching personal and social responsibility - Abstract
Background: Teaching Personal and Social Responsibility (TPSR) has been studied and implemented through physical activity in different backgrounds for over three decades. However, there is no systematized review in the literature concerning the after-school context. Aim: Conducting a systematic review of literature on after-school interventions based on the TPSR model. Methods: This study was driven by the following research questions: Which were the conclusions regarding the implementation of TPSR in after-school settings? Which research methodologies have been used to assess TPSR in after-school time settings? Which results related to TPSR were reported in after-school time settings? Cochrane protocol guidelines were followed. Papers were selected by two independent researchers, with Cohen's Kappa value of 81%. Results and discussion: Twenty-seven papers were selected, thirteen of which were reported with high scores. Most interventions were conducted in the USA on community-based after-school programs, lasting more than nine sessions, and led by school staff who prepared physical activities for youngsters from disadvantaged communities. Most of the reported studies resorted to qualitative methodologies. Some gaps were detected, such as lack of systematization of methods, lack of validity and reliability. Personal and social benefits were found. Other results were grouped into leadership, staff-youngsters relationship, values, transference, and impact on staff lives. We recommend future studies in the after-school context extend to extend to other countries, with more detailed descriptions of the specific used methods. RESUMEN Contexto: Hace más de tres décadas, el Teaching Personal and Social Responsability (TPSR) ha sido estudiado e implementado, a través de la actividad física, en distintos contextos. No obstante, no ha ninguna revisión sistematizada en literatura en un contexto extracurricular. Objetivo: Llevar a una revisión sistemática de la literatura sobre intervenciones extracurriculares basadas en el modelo TPSR. Métodos: Las preguntas de búsqueda que llevaron a este estudio fueron: ¿Cuáles las conclusiones relacionadas a la implementación del TPSR en contexto extracurricular? ¿Qué metodologías de investigación han sido utilizadas para examinar el TPSR en contexto extracurricular? ¿Qué resultados relacionados con el TPSR fueron presentados en contexto extracurricular? Han sido seguidas las orientaciones del protocolo de Cochrane. La selección de los artículos ha sido hecha por dos investigadores independientes, con valor de Kappa de Cohen de 81%. Resultados y discusión: Han sido seleccionados veintisiete artículos, trece de los cuales han sido relatados con elevada puntuación. La mayoría de las intervenciones han sido hechas en los EEUU, en programas extracurriculares para la comunidad, con una duración superior a nueve sesiones, encabezadas por staff de la escuela prepararon actividades físicas para jóvenes de comunidades desfavorecidas. Los estudios relatados apelaron, en su mayoría, a metodologías cualitativas. Algunos errores han sido detectados como la falta de sistematización de los métodos, la falta de validez y fiabilidad. Han sido encontrados beneficios personales y sociales. Otros resultados han sido agrupados en liderazgo, relaciones entre staff y jóvenes, valores, transferencia e impacto en la vida de las personas. Se recomienda que estudios futuros en el contexto extracurricular se extendan a otros países, con descripciones más detalladas de los métodos utilizados y exactos. RESUMO Contexto: Há mais de três décadas, o Teaching Personal and Social Responsibility (TPSR) tem sido estudado e implementado, através da atividade física, em diferentes contextos. No entanto, não há nenhuma revisão sistematizada na literatura em contexto extracurricular. Propósito: Conduzir uma revisão sistemática da literatura sobre intervenções extracurriculares baseadas no modelo TPSR. Métodos: As perguntas de pesquisa que conduziram este estudo foram: quais as conclusões relacionadas à implementação do TPSR em contextos extracurriculares? Que metodologias de investigação têm sido utilizadas para examinar o TPSR em contextos extracurriculares? Que resultados relacionados com o TPSR foram reportados em contextos extracurriculares? Foram seguidas as orientações do protocolo de Cochrane. A seleção dos artigos foi feita por dois pesquisadores independentes, com valor de Kappa de Cohen de 81%. Resultados e discussão: Foram selecionados vinte e sete artigos, treze dos quais foram relatados com elevada pontuação. A maioria das intervenções foi realizada nos EUA, em programas extracurriculares para a comunidade, com uma duração superior a nove sessões, lideradas por staff da escola que preparou atividades físicas para jovens de comunidades desfavorecidas. Os estudos relatados recorreram, na sua maioria, a metodologias qualitativas. Algumas lacunas foram detetadas como a falta de sistematização dos métodos, a falta de validade e confiabilidade. Foram encontrados benefícios pessoais e sociais. Outros resultados foram agrupados em liderança, relacionamento entre staff e jovens, valores, transferência e impacto na vida pessoal. Recomenda-se que estudos futuros no contexto extracurricular se estendam para outros países, com descrições mais detalhadas dos métodos usados e precisos.
- Published
- 2020
4. Mal unión del maléolo medial con incongruencia tibiotalar y sindesmótica: ''resección en caja'' para su tratamiento
- Author
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Caetano, J, primary, Guerra-Pinto, F, additional, Mota-Gomes, T, additional, Duarte-Silva, M, additional, Alves-da Silva, T, additional, and Corte-Real, N, additional
- Published
- 2021
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5. ARTHROSCOPIC REPAIR OF CHRONIC LATERAL ANKLE INSTABILITY
- Author
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Corte-Real, N. and Moreira, R.
- Published
- 2010
6. A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study
- Author
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Guã©rin, C, Beuret, P, Constantin, J, Bellani, G, Garcia-Olivares, P, Roca, O, Meertens, J, Maia, P, Becher, T, Peterson, J, Larsson, A, Gurjar, M, Hajjej, Z, Kovari, F, Assiri, A, Mainas, E, Hasan, M, Morocho-Tutillo, D, Baboi, L, Chrã©tien, J, Franã§ois, G, Ayzac, L, Chen, L, Brochard, L, Mercat, A, Sellami, W, Ferjani, M, Al Bshabshe, A, Almekhlafi, G, Mandourah, Y, Rai, V, Marzida, M, Corcoles Gonzalez, V, Sanchez Iniesta, R, Garcia, P, Garcia-Montesinos de la Peña, M, Garcia Herrera, A, Garcia-de-Acilu, M, Masclans Enviz, J, Mancebo, J, Heili, S, Artigas Raventos, A, Blanch Torra, L, Roche-Campo, F, Rialp, G, Forteza, C, Berrazueta, A, Martinez, E, Penuelas, O, Jara-Rubio, R, Mallat, J, Thevenin, D, Zogheib, E, Levrat, A, Porot, V, Bedock, B, Grech, L, Plantefeve, G, Badie, J, Besch, G, Pili-Floury, S, Guisset, O, Robine, A, Prat, G, Doise, J, Badet, M, Thouret, J, Just, B, Perbet, S, Lautrette, A, Souweine, B, Chabanne, R, Danguy des Déserts, M, Rigaud, J, Marchalot, A, Bele, N, Beague, S, Hours, S, Marque, S, Durand, M, Payen, J, Stoclin, A, Gaffinel, A, Winer, A, Chudeau, N, Tirot, P, Thyrault, M, Paulet, R, Aubrun, F, Guerin, C, Floccard, B, Rimmele, T, Argaud, L, Hernu, R, Crozon Clauzel, J, Wey, P, Bourdin, G, Pommier, C, Cueuille, N, de Varax, N, Marchi, E, Papazian, L, Jochmans, S, Monchi, M, Jaber, S, de Jong, A, Moulaire, V, Capron, M, Jarrige, L, Barberet, G, Lakhal, K, Rozec, B, Dellamonica, J, Robert, A, Bernardin, G, Danin, P, Raucoules, M, Runge, I, Foucrier, A, Hamada, S, Tesniere, A, Fromentin, M, Samama, C, Mira, J, Diehl, J, Mekontso Dessap, A, Arbelot, C, Demoule, A, Roche, A, Similowski, T, Ricard, J, Gaudry, S, Dreyfuss, D, de Montmolin, E, da Silva, D, Verdiere, B, Ardisson, F, Lemiale, V, Azoulay, E, Bruel, C, Tiercelet, K, Fartoukh, M, Voiriot, G, Hoffmann, C, Leclerc, T, Thille, A, Robert, R, Beduneau, G, Beuzelin, M, Tamion, F, Morel, J, Tremblay, A, Molliex, S, Amal, J, Meaudre, E, Goutorbe, P, Laffon, M, Gros, A, Nica, A, Barjon, G, Dahyot-Fizelier, C, Imzi, N, Gally, J, Real, N, Sauneuf, B, Souloy, X, Girbes, A, Tuinman, P, Schultz, M, Winters, T, Mijzen, L, Roekaerts, P, Vermeijden, W, Beishuizen, A, Trof, R, Corsten, S, Kesecioglu, J, Dieperink, W, Pickers, P, Roovers, N, Duque, M, Rua, F, Pereira de Figueired, A, Ramos, A, Fragoso, E, Azevedo, P, Gouveia, J, Costa E. Silva, Z, Silva, G, Chaves, S, Nobrega, J, Lopes, L, Valerio, B, Araujo, A, de Freitas, P, Bouw, M, Melao, M, Granja, C, Marcal, P, Fernandes, A, Joao, G, Maia, D, Spadaro, S, Volta, C, Citerio, G, Mauri, T, Alban, L, Pesenti, A, Mistraletti, G, Formenti, P, Tommasino, C, Tardini, F, Fumagalli, R, Colombo, R, Fossali, T, Catena, E, Todeschini, M, Gnesin, P, Cracchiolo, A, Palma, D, Tetamo, R, Albiero, D, Costantini, E, Raimondi, F, Coppadoro, A, Vascotto, E, Lusenti, F, Schã¤dler, D, Weiler, N, Karagiannidis, C, Petersson, J, Konrad, D, Kawati, R, Wessbergh, J, Valtysson, J, Rockstroh, M, Borgstrom, S, Larsson, N, Thunberg, J, Camsooksai, J, Briggs, N, Cuesta, J, Anwar, S, Oâ€TMBrien, B, Barberis, L, Sturman, J, Karatzas, S, Piza, P, Sottiaux, T, Adam, J, Gawda, R, Gawor, M, Alqdah, M, Cohen, D, Baker, A, Ñamendys-Silva, S, Garcia-Guillen, F, Morocho Tutillo, D, Jibaja Vega, M, Zakalik, G, Pagella, G, Marengo, J, Guérin, C., Beuret, P., Constantin, J. M., Bellani, G., Garcia-Olivares, P., Roca, O., Meertens, J. H., Maia, P. Azevedo, Becher, T., Peterson, J., Larsson, A., Gurjar, M., Hajjej, Z., Kovari, F., Assiri, A. H., Mainas, E., Hasan, M. S., Morocho-Tutillo, D. R., Baboi, L., Chrétien, J. M., François, G., Ayzac, L., Chen, L., Brochard, L., Mercat, A., Hajjej, Zied, Sellami, Walid, Ferjani, M., Gurjar, Mohan, Assiri, Amer, Al Bshabshe, Ali, Almekhlafi, Ghaleb, Mandourah, Yasser, Hasan, Mohd Shahnaz, Rai, Vineya, Marzida, M., Corcoles Gonzalez, Virgilio, Sanchez Iniesta, Rafael, Garcia, Pablo, Garcia-Montesinos de la Peña, Manuel, Garcia Herrera, Adriana, Roca, Oriol, Garcia-de-Acilu, Marina, Masclans Enviz, Joan Ramon, Mancebo, Jordi, Heili, Sarah, Artigas Raventos, Antonio, Blanch Torra, LluÃs, Roche-Campo, Ferran, Rialp, Gemma, Forteza, Catalina, Berrazueta, Ana, Martinez, Esther, Penuelas, Oscar, Jara-Rubio, Ruben, Mallat, Jihad, Thevenin, D., Zogheib, Elie, Mercat, Alain, Levrat, Albrice, Porot, Veronique, Bedock, B., Grech, Ludovic, Plantefeve, Gaetan, Badie, Julio, Besch, Guillaume, Pili-Floury, Sébastien, Guisset, Olivier, Robine, Adrien, Prat, Gwenael, Doise, Jean-Marc, Badet, Michel, Thouret, J. M., Just, Bernard, Perbet, Sébastien, Lautrette, Alexandre, Souweine, B., Chabanne, Russell, Danguy des Déserts, Marc, Rigaud, Jean-Philippe, Marchalot, Antoine, Rigaud, J. P., Bele, Nicolas, Beague, Sébastien, Hours, Sandrine, Marque, Sophie, Durand, Michel, Payen, J. F., Stoclin, Annabelle, Gaffinel, Alain, Winer, Arnaud, Chudeau, Nicolas, Tirot, Patrice, Thyrault, Martial, Paulet, Rémi, Thyrault, M., Aubrun, Frederic, Guerin, Claude, Floccard, Bernard, Rimmele, T., Argaud, Laurent, Hernu, Romain, Crozon Clauzel, Jullien, Wey, Pierre-François, Bourdin, Gael, Pommier, C., Cueuille, NadÃge, de Varax, null, Marchi, Elisa, Papazian, L., Jochmans, Sebastien, Monchi, M., Jaber, Samir, de Jong, Audrey, Moulaire, Valerie, Capron, Matthieu, Jarrige, L., Barberet, Guillaume, Lakhal, Karim, Rozec, B., Dellamonica, Jean, Robert, Alexandre, Bernardin, G., Danin, Pierre-Eric, Raucoules, M., Runge, Isabelle, Foucrier, Arnaud, Hamada, Sophie, Tesniere, Antoine, Fromentin, Mélanie, Samama, C. M., Mira, Jean-Paul, Diehl, Jean-Luc, Mekontso Dessap, Armand, Arbelot, Charlotte, Demoule, Alexandre, Roche, Anne, Similowski, T., Ricard, Jean-Damien, Gaudry, Stéphane, Dreyfuss, D., de Montmolin, Etienne, da Silva, Daniel, Verdiere, B., Ardisson, Fanny, Lemiale, Virginie, Azoulay, Elie, Bruel, Cédric, Tiercelet, Kelly, Fartoukh, Muriel, Voiriot, Guillaume, Hoffmann, Clement, Leclerc, T., Thille, Arnaud, Robert, Réné, Beuret, Pascal, Beduneau, Gaëtan, Beuzelin, Marion, Tamion, F., Morel, Jérà ́me, Tremblay, Aymeric, Molliex, S., Amal, Jean-Michel, Meaudre, Eric, Goutorbe, Philippe, Laffon, Marc, Gros, Antoine, Nica, Alexandru, Barjon, Genevieve, Dahyot-Fizelier, Claire, Imzi, Nadia, Gally, Josette, Real, null, Sauneuf, Bertrand, Souloy, Xavier, Girbes, Armand, Tuinman, Pieter Roel, Schultz, Marcus, Winters, Tineke, Mijzen, Lisa, Roekaerts, P. M. H. J., Vermeijden, Wytze, Beishuizen, Albertus, Trof, R., Corsten, Stijn, Kesecioglu, Jozef, Meertens, John, Dieperink, Wim, Pickers, Peter, Roovers, Noortje, Maia, Paulo, Duque, Melanie, Rua, Fernando, Pereira de Figueired, AntÃ3nio Manuel, Ramos, Armindo, Fragoso, Elsa, Azevedo, Pilar, Gouveia, Joao, Costa E. Silva, Zélia, Silva, Goncalo, Chaves, Susana, Nobrega, J. J., Lopes, LuÃs, Valerio, Bernardino, Araujo, Ana Carolina, de Freitas, Paulo Telles, Bouw, Maria Jose, Melao, Maria, Granja, C., Marcal, Paulo, Fernandes, Antero, Joao, Gonçalves Pereira, Maia, DionÃsio Faria, Spadaro, Savino, Volta, Carlo Alberto, Bellani, Giacomo, Citerio, G., Mauri, Tommaso, Alban, Laura, Pesenti, A., Mistraletti, Giovanni, Formenti, Paolo, Tommasino, C., Tardini, Francesca, Fumagalli, R., Colombo, Riccardo, Fossali, Tommaso, Catena, E., Todeschini, Manuel, Gnesin, Paolo, Cracchiolo, Andrea Neville, Palma, Daniela, Tetamo, R., Albiero, Daniela, Costantini, Elena, Raimondi, F., Coppadoro, Andrea, Vascotto, Ettore, Lusenti, F., Becher, Tobias, Schädler, Dirk, Weiler, N., Karagiannidis, Christian, Petersson, Johan, Konrad, D., Kawati, Rafael, Wessbergh, Joanna, Valtysson, J., Rockstroh, Matthias, Borgstrom, Sten, Larsson, Niklas, Thunberg, J., Camsooksai, Julie, Briggs, null, Kovari, Ferenc, Cuesta, J., Anwar, Sibs, Oâ€TMBrien, B., Barberis, Luigi, Sturman, J., Mainas, Efstratios, Karatzas, S., Piza, Petr, Sottiaux, Thierry, Adam, J. F., Gawda, Ryszard, Gawor, Maen, Alqdah, M., Cohen, D., Brochard, Laurent, Baker, A., Ñamendys-Silva, Silvio Antonio, Garcia-Guillen, Francisco Javier, Morocho Tutillo, Diego Rolando, Jibaja Vega, Manuel, Zakalik, Graciela, Pagella, Gonzalo, Marengo, J., Guã©rin, C, Beuret, P, Constantin, J, Bellani, G, Garcia-Olivares, P, Roca, O, Meertens, J, Maia, P, Becher, T, Peterson, J, Larsson, A, Gurjar, M, Hajjej, Z, Kovari, F, Assiri, A, Mainas, E, Hasan, M, Morocho-Tutillo, D, Baboi, L, Chrã©tien, J, Franã§ois, G, Ayzac, L, Chen, L, Brochard, L, Mercat, A, Sellami, W, Ferjani, M, Al Bshabshe, A, Almekhlafi, G, Mandourah, Y, Rai, V, Marzida, M, Corcoles Gonzalez, V, Sanchez Iniesta, R, Garcia, P, Garcia-Montesinos de la Peña, M, Garcia Herrera, A, Garcia-de-Acilu, M, Masclans Enviz, J, Mancebo, J, Heili, S, Artigas Raventos, A, Blanch Torra, L, Roche-Campo, F, Rialp, G, Forteza, C, Berrazueta, A, Martinez, E, Penuelas, O, Jara-Rubio, R, Mallat, J, Thevenin, D, Zogheib, E, Levrat, A, Porot, V, Bedock, B, Grech, L, Plantefeve, G, Badie, J, Besch, G, Pili-Floury, S, Guisset, O, Robine, A, Prat, G, Doise, J, Badet, M, Thouret, J, Just, B, Perbet, S, Lautrette, A, Souweine, B, Chabanne, R, Danguy des Déserts, M, Rigaud, J, Marchalot, A, Bele, N, Beague, S, Hours, S, Marque, S, Durand, M, Payen, J, Stoclin, A, Gaffinel, A, Winer, A, Chudeau, N, Tirot, P, Thyrault, M, Paulet, R, Aubrun, F, Guerin, C, Floccard, B, Rimmele, T, Argaud, L, Hernu, R, Crozon Clauzel, J, Wey, P, Bourdin, G, Pommier, C, Cueuille, N, de Varax, N, Marchi, E, Papazian, L, Jochmans, S, Monchi, M, Jaber, S, de Jong, A, Moulaire, V, Capron, M, Jarrige, L, Barberet, G, Lakhal, K, Rozec, B, Dellamonica, J, Robert, A, Bernardin, G, Danin, P, Raucoules, M, Runge, I, Foucrier, A, Hamada, S, Tesniere, A, Fromentin, M, Samama, C, Mira, J, Diehl, J, Mekontso Dessap, A, Arbelot, C, Demoule, A, Roche, A, Similowski, T, Ricard, J, Gaudry, S, Dreyfuss, D, de Montmolin, E, da Silva, D, Verdiere, B, Ardisson, F, Lemiale, V, Azoulay, E, Bruel, C, Tiercelet, K, Fartoukh, M, Voiriot, G, Hoffmann, C, Leclerc, T, Thille, A, Robert, R, Beduneau, G, Beuzelin, M, Tamion, F, Morel, J, Tremblay, A, Molliex, S, Amal, J, Meaudre, E, Goutorbe, P, Laffon, M, Gros, A, Nica, A, Barjon, G, Dahyot-Fizelier, C, Imzi, N, Gally, J, Real, N, Sauneuf, B, Souloy, X, Girbes, A, Tuinman, P, Schultz, M, Winters, T, Mijzen, L, Roekaerts, P, Vermeijden, W, Beishuizen, A, Trof, R, Corsten, S, Kesecioglu, J, Dieperink, W, Pickers, P, Roovers, N, Duque, M, Rua, F, Pereira de Figueired, A, Ramos, A, Fragoso, E, Azevedo, P, Gouveia, J, Costa E. Silva, Z, Silva, G, Chaves, S, Nobrega, J, Lopes, L, Valerio, B, Araujo, A, de Freitas, P, Bouw, M, Melao, M, Granja, C, Marcal, P, Fernandes, A, Joao, G, Maia, D, Spadaro, S, Volta, C, Citerio, G, Mauri, T, Alban, L, Pesenti, A, Mistraletti, G, Formenti, P, Tommasino, C, Tardini, F, Fumagalli, R, Colombo, R, Fossali, T, Catena, E, Todeschini, M, Gnesin, P, Cracchiolo, A, Palma, D, Tetamo, R, Albiero, D, Costantini, E, Raimondi, F, Coppadoro, A, Vascotto, E, Lusenti, F, Schã¤dler, D, Weiler, N, Karagiannidis, C, Petersson, J, Konrad, D, Kawati, R, Wessbergh, J, Valtysson, J, Rockstroh, M, Borgstrom, S, Larsson, N, Thunberg, J, Camsooksai, J, Briggs, N, Cuesta, J, Anwar, S, Oâ€TMBrien, B, Barberis, L, Sturman, J, Karatzas, S, Piza, P, Sottiaux, T, Adam, J, Gawda, R, Gawor, M, Alqdah, M, Cohen, D, Baker, A, Ñamendys-Silva, S, Garcia-Guillen, F, Morocho Tutillo, D, Jibaja Vega, M, Zakalik, G, Pagella, G, Marengo, J, Guérin, C., Beuret, P., Constantin, J. M., Bellani, G., Garcia-Olivares, P., Roca, O., Meertens, J. H., Maia, P. Azevedo, Becher, T., Peterson, J., Larsson, A., Gurjar, M., Hajjej, Z., Kovari, F., Assiri, A. H., Mainas, E., Hasan, M. S., Morocho-Tutillo, D. R., Baboi, L., Chrétien, J. M., François, G., Ayzac, L., Chen, L., Brochard, L., Mercat, A., Hajjej, Zied, Sellami, Walid, Ferjani, M., Gurjar, Mohan, Assiri, Amer, Al Bshabshe, Ali, Almekhlafi, Ghaleb, Mandourah, Yasser, Hasan, Mohd Shahnaz, Rai, Vineya, Marzida, M., Corcoles Gonzalez, Virgilio, Sanchez Iniesta, Rafael, Garcia, Pablo, Garcia-Montesinos de la Peña, Manuel, Garcia Herrera, Adriana, Roca, Oriol, Garcia-de-Acilu, Marina, Masclans Enviz, Joan Ramon, Mancebo, Jordi, Heili, Sarah, Artigas Raventos, Antonio, Blanch Torra, LluÃs, Roche-Campo, Ferran, Rialp, Gemma, Forteza, Catalina, Berrazueta, Ana, Martinez, Esther, Penuelas, Oscar, Jara-Rubio, Ruben, Mallat, Jihad, Thevenin, D., Zogheib, Elie, Mercat, Alain, Levrat, Albrice, Porot, Veronique, Bedock, B., Grech, Ludovic, Plantefeve, Gaetan, Badie, Julio, Besch, Guillaume, Pili-Floury, Sébastien, Guisset, Olivier, Robine, Adrien, Prat, Gwenael, Doise, Jean-Marc, Badet, Michel, Thouret, J. M., Just, Bernard, Perbet, Sébastien, Lautrette, Alexandre, Souweine, B., Chabanne, Russell, Danguy des Déserts, Marc, Rigaud, Jean-Philippe, Marchalot, Antoine, Rigaud, J. P., Bele, Nicolas, Beague, Sébastien, Hours, Sandrine, Marque, Sophie, Durand, Michel, Payen, J. F., Stoclin, Annabelle, Gaffinel, Alain, Winer, Arnaud, Chudeau, Nicolas, Tirot, Patrice, Thyrault, Martial, Paulet, Rémi, Thyrault, M., Aubrun, Frederic, Guerin, Claude, Floccard, Bernard, Rimmele, T., Argaud, Laurent, Hernu, Romain, Crozon Clauzel, Jullien, Wey, Pierre-François, Bourdin, Gael, Pommier, C., Cueuille, NadÃge, de Varax, null, Marchi, Elisa, Papazian, L., Jochmans, Sebastien, Monchi, M., Jaber, Samir, de Jong, Audrey, Moulaire, Valerie, Capron, Matthieu, Jarrige, L., Barberet, Guillaume, Lakhal, Karim, Rozec, B., Dellamonica, Jean, Robert, Alexandre, Bernardin, G., Danin, Pierre-Eric, Raucoules, M., Runge, Isabelle, Foucrier, Arnaud, Hamada, Sophie, Tesniere, Antoine, Fromentin, Mélanie, Samama, C. M., Mira, Jean-Paul, Diehl, Jean-Luc, Mekontso Dessap, Armand, Arbelot, Charlotte, Demoule, Alexandre, Roche, Anne, Similowski, T., Ricard, Jean-Damien, Gaudry, Stéphane, Dreyfuss, D., de Montmolin, Etienne, da Silva, Daniel, Verdiere, B., Ardisson, Fanny, Lemiale, Virginie, Azoulay, Elie, Bruel, Cédric, Tiercelet, Kelly, Fartoukh, Muriel, Voiriot, Guillaume, Hoffmann, Clement, Leclerc, T., Thille, Arnaud, Robert, Réné, Beuret, Pascal, Beduneau, Gaëtan, Beuzelin, Marion, Tamion, F., Morel, Jérà ́me, Tremblay, Aymeric, Molliex, S., Amal, Jean-Michel, Meaudre, Eric, Goutorbe, Philippe, Laffon, Marc, Gros, Antoine, Nica, Alexandru, Barjon, Genevieve, Dahyot-Fizelier, Claire, Imzi, Nadia, Gally, Josette, Real, null, Sauneuf, Bertrand, Souloy, Xavier, Girbes, Armand, Tuinman, Pieter Roel, Schultz, Marcus, Winters, Tineke, Mijzen, Lisa, Roekaerts, P. M. H. J., Vermeijden, Wytze, Beishuizen, Albertus, Trof, R., Corsten, Stijn, Kesecioglu, Jozef, Meertens, John, Dieperink, Wim, Pickers, Peter, Roovers, Noortje, Maia, Paulo, Duque, Melanie, Rua, Fernando, Pereira de Figueired, AntÃ3nio Manuel, Ramos, Armindo, Fragoso, Elsa, Azevedo, Pilar, Gouveia, Joao, Costa E. Silva, Zélia, Silva, Goncalo, Chaves, Susana, Nobrega, J. J., Lopes, LuÃs, Valerio, Bernardino, Araujo, Ana Carolina, de Freitas, Paulo Telles, Bouw, Maria Jose, Melao, Maria, Granja, C., Marcal, Paulo, Fernandes, Antero, Joao, Gonçalves Pereira, Maia, DionÃsio Faria, Spadaro, Savino, Volta, Carlo Alberto, Bellani, Giacomo, Citerio, G., Mauri, Tommaso, Alban, Laura, Pesenti, A., Mistraletti, Giovanni, Formenti, Paolo, Tommasino, C., Tardini, Francesca, Fumagalli, R., Colombo, Riccardo, Fossali, Tommaso, Catena, E., Todeschini, Manuel, Gnesin, Paolo, Cracchiolo, Andrea Neville, Palma, Daniela, Tetamo, R., Albiero, Daniela, Costantini, Elena, Raimondi, F., Coppadoro, Andrea, Vascotto, Ettore, Lusenti, F., Becher, Tobias, Schädler, Dirk, Weiler, N., Karagiannidis, Christian, Petersson, Johan, Konrad, D., Kawati, Rafael, Wessbergh, Joanna, Valtysson, J., Rockstroh, Matthias, Borgstrom, Sten, Larsson, Niklas, Thunberg, J., Camsooksai, Julie, Briggs, null, Kovari, Ferenc, Cuesta, J., Anwar, Sibs, Oâ€TMBrien, B., Barberis, Luigi, Sturman, J., Mainas, Efstratios, Karatzas, S., Piza, Petr, Sottiaux, Thierry, Adam, J. F., Gawda, Ryszard, Gawor, Maen, Alqdah, M., Cohen, D., Brochard, Laurent, Baker, A., Ñamendys-Silva, Silvio Antonio, Garcia-Guillen, Francisco Javier, Morocho Tutillo, Diego Rolando, Jibaja Vega, Manuel, Zakalik, Graciela, Pagella, Gonzalo, and Marengo, J.
- Abstract
Introduction: While prone positioning (PP) has been shown to improve patient survival in moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of application of PP in clinical practice still appears low. Aim: This study aimed to determine the prevalence of use of PP in ARDS patients (primary endpoint), the physiological effects of PP, and the reasons for not using it (secondary endpoints). Methods: The APRONET study was a prospective international 1-day prevalence study performed four times in April, July, and October 2016 and January 2017. On each study day, investigators in each ICU had to screen every patient. For patients with ARDS, use of PP, gas exchange, ventilator settings and plateau pressure (Pplat) were recorded before and at the end of the PP session. Complications of PP and reasons for not using PP were also documented. Values are presented as median (1st–3rd quartiles). Results: Over the study period, 6723 patients were screened in 141 ICUs from 20 countries (77% of the ICUs were European), of whom 735 had ARDS and were analyzed. Overall 101 ARDS patients had at least one session of PP (13.7%), with no differences among the 4 study days. The rate of PP use was 5.9% (11/187), 10.3% (41/399) and 32.9% (49/149) in mild, moderate and severe ARDS, respectively (P = 0.0001). The duration of the first PP session was 18 (16–23) hours. Measured with the patient in the supine position before and at the end of the first PP session, PaO 2 /F I O 2 increased from 101 (76–136) to 171 (118–220) mmHg (P = 0.0001) driving pressure decreased from 14 [11–17] to 13 [10–16] cmH 2 O (P = 0.001), and Pplat decreased from 26 [23–29] to 25 [23–28] cmH 2 O (P = 0.04). The most prevalent reason for not using PP (64.3%) was that hypoxemia was not considered sufficiently severe. Complications were reported in 12 patients (11.9%) in whom PP was used (pressure sores in five, hypoxemia in two, endotracheal tube-related in two ocular in two, and a transient
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- 2018
7. Teaching personal and social responsibility after-school: A systematic review.
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Baptista, C., Corte-Real, N., Regueiras, L., Seo, G., Hemphill, M., Pereira, A., Dias, C., Martinek, T., and Fonseca, A.
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SOCIAL responsibility ,AFTER school programs ,PHYSICAL activity ,TEACHING ,META-analysis - Abstract
Copyright of Cuadernos de Psicología del Deporte is the property of Cuadernos de Psicologia del Deporte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2020
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8. Influence of local drainage on calcaneal fractures’ surgical treatment complications
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Figueiredo, J., primary, Côrte-Real, N., additional, Martinho, C., additional, Silva, M. Duarte, additional, Wircker, P., additional, Caetano, J., additional, and Dias, R., additional
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- 2017
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9. Medial maleollus rotational malunion – Case report
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Duarte-Silva, M., primary, Guerra-Pinto, F., additional, Wircker, P., additional, Caetano, J., additional, Dias, R., additional, Figueiredo, J., additional, and Côrte-Real, N., additional
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- 2017
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10. Isolated peritalar dislocation – A report of two cases
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Dias, R., primary, Caetano, J., additional, Wircker, P., additional, Figueiredo, J., additional, and Côrte-Real, N., additional
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- 2017
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11. Arthroscopic repair of acute rupture of the deltoid ligament
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Wircker, P., primary, Duarte Silva, M., additional, Caetano, J., additional, Dias, R., additional, Figueiredo, J., additional, Alves da Silva, T., additional, and Côrte-Real, N., additional
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- 2017
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12. Apicobasal Polarity Controls Lymphocyte Adhesion to Hepatic Epithelial Cells
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Reglero-Real N, Alvarez-Varela A, Cernuda-Morollón E, Feito J, Marcos-Ramiro B, Fernández-Martín L, Gómez-Lechón MJ, Muntané J, Sandoval P, Majano PL, Correas I, Alonso MA, and Millán J
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EXPRESSION ,RECRUITMENT ,MOLECULE-1 ICAM-1 ,POLARIZATION ,MIGRATION ,EZRIN/RADIXIN/MOESIN PROTEINS ,SEGREGATION ,ASSOCIATION ,RADIXIN ,HEPATOCYTES - Abstract
Loss of apicobasal polarity is a hallmark of epithelial pathologies. Leukocyte infiltration and crosstalk with dysfunctional epithelial barriers are crucial for the inflammatory response. Here, we show that apicobasal architecture regulates the adhesion between hepatic epithelial cells and lymphocytes. Polarized hepatocytes and epithelium from bile ducts segregate the intercellular adhesion molecule 1 (ICAM-1) adhesion receptor onto their apical, microvilli-rich membranes, which are less accessible by circulating immune cells. Upon cell depolarization, hepatic ICAM-1 becomes exposed and increases lymphocyte binding. Polarized hepatic cells prevent ICAM-1 exposure to lymphocytes by redirecting basolateral ICAM-1 to apical domains. Loss of ICAM-1 polarity occurs in human inflammatory liver diseases and can be induced by the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha). We propose that adhesion receptor polarization is a parenchymal immune checkpoint that allows functional epithelium to hamper leukocyte binding. This contributes to the haptotactic guidance of leukocytes toward neigh boring damaged or chronically inflamed epithelial cells that expose their adhesion machinery.
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- 2014
13. Arthroscopic treatment for chronic achilles tendon rupture on high demand patients
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Côrte-Real, N., primary, Silva, M., additional, Wircker, P., additional, and Pinto, F., additional
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- 2016
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14. Luxação Palmar Isolada da Quinta Articulação Carpo-Metacárpica
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Barros, A, Pinto, F, Varela, E, Almeida, R, and Côrte-Real, N
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Tratamento ,Luxação ,HCC ORT - Abstract
A luxação palmar isolada da quinta articulação carpo-metacárpica é rara. Esta lesão pode passar despercebida, sendo importante a suspeita clínica, levando a uma avaliação radiológica no perfil e incidências obliquas. O tratamento é controverso, estando descritas a redução fechada com fixação percutânea com fios de Kirshner percutâneos e a redução aberta com fixação interna. Apresentamos um caso clínico de luxação palmar do tipo cubital isolada e o seu tratamento. O resultado funcional aos 6 meses, de acordo com o score DASH, foi de 0.8. Apresentava-se sem queixas, desempenhado as suas atividades diárias sem restrições. info:eu-repo/semantics/publishedVersion
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- 2012
15. Potential of Multi-temporal InSAR Techniques for Structural Health Monitoring
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Lazecky, Milan, primary, Bakon, Matus, additional, Sousa, Joaquim J., additional, Perissin, Daniele, additional, Hlavacova, Ivana, additional, Patricio, Gloria, additional, Papco, Juraj, additional, Rapant, P., additional, and Real, N., additional
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- 2015
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16. Monitoring of landslide activity in Slovakia territory using multi-temporal InSAR techniques
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Bakon, Matus, primary, Papco, Juraj, additional, Perissin, Daniele, additional, Lazecky, Milan, additional, Sousa, Joaquim Joao, additional, Hlavacova, Ivana, additional, Batorova, Kristina, additional, Ondrejka, Peter, additional, Liscak, Pavel, additional, Paudits, Peter, additional, and Real, N., additional
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- 2015
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17. Increased apoptosis and reduced replication efficiency of the E3 region-modified dl309 adenovirus in cancer cells
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Hibma, M., Real, N., Wiles, A., Dobson-Le, D., Dix, Brett, Wynford-thomas, D., Braithwaite, A., Royds, J., Hibma, M., Real, N., Wiles, A., Dobson-Le, D., Dix, Brett, Wynford-thomas, D., Braithwaite, A., and Royds, J.
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- 2009
18. El proyecto 'Público y museos'
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Clara, Antonella, Asensio, Mikel, Pol Méndez, Elena, Fernández, H., Real, N., Gomis, M., Llera, B., Olveira, R., Angeles, Margarita de los, González Casarrubios, Consolación, Simón Rueda, Cecilia, Polo Herrador, María de los Angeles, Clara, Antonella, Asensio, Mikel, Pol Méndez, Elena, Fernández, H., Real, N., Gomis, M., Llera, B., Olveira, R., Angeles, Margarita de los, González Casarrubios, Consolación, Simón Rueda, Cecilia, and Polo Herrador, María de los Angeles
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- 1998
19. ‘Chevron’ osteotomy fixed with biodegradable screws in the treatment of Hallux valgus
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Côrte-Real, N., primary, Vasco Silva, J., additional, Esquível Pereira, J., additional, and Caramelo, J., additional
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- 1998
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20. Congenital hallux varus
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Côrte-Real, N., primary and Caramelo, J., additional
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- 1997
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21. The knowledge and actions of the coaches in competitive situations: The perception of the coaches of the Brazilian volleyball Superleague,O conhecimento e ações do treinador em situações de competição: O estudo da percepção dos treinadores da Superliga Brasileira de voleibol
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Vieira, A. L. B., Cláudia Dias, Corte-Real, N., and Fonseca, A. M.
22. Coaches' perceptions on the role played by football on positive development of underserved youth: What reality?,As perceções de treinadores acerca do papel do futebol no desenvolvimento positivo de jovens em risco de exclusão social: Que realidade?
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Santos, F., Corte-Real, N., Regueiras, L., Cláudia Dias, and Fonseca, A.
23. Emotions in sport: What we know and what (we feel) we think we know,Emoções no desporto: O que sabemos e o (que sentimos) que julgamos saber
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Cláudia Dias, Corte-Real, N., Cruz, J. F., and Fonseca, A. M.
24. Coaches' role in positive youth development through sport: From what we know to what we need to know,O papel do treinador no desenvolvimento positivo dos jovens através do desporto: Do que sabemos ao que precisamos saber
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Santos, F., Côrte-Real, N., Regueiras, L., Cláudia Dias, and Fonseca, A.
25. Business intelligence maturity assessment model for organizations
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Côrte-Real, N., Miguel Neto, and Neves, F.
26. Cognitive appraisals, emotions and coping: A study of portuguese footballers,Avaliações cognitivas, emoções e coping: Um estudo com futebolistas portugueses
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Ribeiro, R., Cláudia Dias, Cruz, J. F., Corte-Real, N., and Fonseca, A.
27. How to measure children with cerebral palsy's perception of competence and social acceptance? Preliminary study to determinate the psychometric properties of the Portuguese version of the Dutch Pictorial Scale of Perceived Competence and Social Acceptance in Children with Cerebral Palsy | Como avaliar a percepção de competência e aceitação social de crianças com paralisia cerebral? Estudo inicial para a determinação das propriedades psicométricas da versão portuguesa da Dutch Pictorial Scale of Perceived Competence and Social Acceptance in Children with Cerebral Palsy
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Corredeira, R. M. N., Real, N. J. C. A., Dias, C. S. L., Da Silva, M. A. S. P. M., and Antonio Manuel Fonseca
28. Cross-cultural adaptation of Empowering Disempowering Motivational Climate Questionnaire for Portuguese language and analysis of invariance in Brazilian and Portuguese male athletes,Adaptação transcultural do Empowering Disempowering Motivational Climate Questionnaire para a língua portuguesa e análise da invariância em atletas masculinos brasileiros e portugueses
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Oliveira, H. Z., Dias, T. S., Sabino, B., Dias, C., Corte-Real, N., Maia, J. A., and Fonseca, A.
29. [Emotions in sport: What we know and (what we feel) we think we know.] Emoções no desporto: O que sabemos e o (que sentimos) que julgamos saber
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Dias, C., Corte-Real, N., José Cruz, and Fonseca, A. M.
30. Avaliação da maturidade das plataformas de business intelligence
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Côrte-Real, N. and Miguel Neto
31. How to distinguish between young athletes who intend to continue playing sports and those who do not intend to continue doing it?,¿Como distinguir entre jóvenes atletas que tienen la intención de continuar practicando deporte de los que no piensan continuar haciéndolo?
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Cláudia Dias, Corte-Real, N., Barreiros, A., Brustad, R., and Fonseca, A. M.
32. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells
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Bernabé-Rubio M, Andrés G, Casares-Arias J, Fernández-Barrera J, Rangel L, Reglero-Real N, Dc, Gershlick, Jj, Fernández, Millán J, Correas I, Dg, Miguez, and Ma, Alonso
33. Quality indicators in interhospital transport: Multicentre project
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Teresa Escaplés Giménez, Pedro Domínguez Sampedro, Kai Boris Brandstrup Azuero, Juan Diego Toledo Parreño, Beatriz Garrido Conde, Itziar Marsinyach Ros, Nuria Millán García Del Real, María Del Mar Nuñez Cárdenas, Institut Català de la Salut, [Garrido Conde B] Unidad de Transporte Pediátrico Balear, Hospital Son Espases, Palma, Mallorca, Spain. [Millán García del Real N] SEMP, Hospital Sant Joan de Deu, Barcelona, Spain. [Escaplés Giménez T, Domínguez Sampedro P] SEMP, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Marsinyach Ros I] Unidad Transporte Neonatal de Madrid, Madrid, Spain. [Toledo Parreño JD] Unidad Transporte Pediátrico y Neonatal de Castellón, Castellón, Spain. [Nuñez Cárdenas MM] UCIP Hospital Virgen del Rocío, Sevilla, Spain, and Vall d'Hebron Barcelona Hospital Campus
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Consensus ,Computer science ,media_common.quotation_subject ,Delphi method ,Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus [PSYCHIATRY AND PSYCHOLOGY] ,conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso [PSIQUIATRÍA Y PSICOLOGÍA] ,Pediatrics ,RJ1-570 ,Management of Technology and Innovation ,Indicadors de salut ,Humans ,Quality (business) ,Operations management ,Relevance (information retrieval) ,Assistència sanitària - Presa de decisions ,Child ,Neonatologia ,Quality Indicators, Health Care ,media_common ,Research method ,Evaluación de calidad ,Transporte interhospitalario ,Paediatric intensive care ,Mejora de calidad ,Quality measurement ,Benchmarking ,administración de los servicios de salud::calidad de la atención sanitaria::indicadores de calidad en la asistencia sanitaria [ATENCIÓN DE SALUD] ,Spain ,Indicadores de calidad ,Health Services Administration::Quality of Health Care::Quality Indicators, Health Care [HEALTH CARE] ,Health Occupations::Medicine::Pediatrics::Neonatology [DISCIPLINES AND OCCUPATIONS] ,Work teams ,Neonatology ,profesiones sanitarias::medicina::pediatría::neonatología [DISCIPLINAS Y OCUPACIONES] - Abstract
Indicadores de calidad; Transporte interhospitalario; Mejora de calidad Quality indicators; Interhospital transport; Quality improvement Indicadors de qualitat; Transport interhospitalari; Millora de la qualitat Introduction Interhospital transport is carried out by variable teams in different regions of our country, and this makes quality evaluation and benchmarking complicated. Project objective: Select and define a consensual list of quality measurement that may be used by national transport units, whether specialised or not. Methods Initial set of quality indicators was proposed by coordinators (members of representative specialised transport units in Spain). Evaluation by selected transport specialists from participating units and SECIP (Society of Paediatric Intensive Care) and SENeo (Spanish Neonatology Society) work teams. Selection of definitive indicators by Delphi method according to relevance and feasibility. Results A total of 35 quality indicators were included in the initial set. Evaluation was carried out by 22 specialists from 7 transport teams. In a first round, 4 indicators were consensually included in the definitive list. Results for the rest of metrics and comments were sent to all participants, and after a second assessment, 11 other indicators reached enough consensus. After list accomplishment, a consensual final definition for every indicator was established. Conclusions Using a consensual research method, a list of 15 common indicators was obtained, which may be used by specialised transport teams in our country, and by non-specialised clinics in charge of interhospital paediatric transport. It will allow individual performance to be assessed, as well as benchmarking, in order to find improvement opportunities and ensure the highest quality during interhospital transport. Introducción El traslado interhospitalario se realiza por equipos muy diferentes en las distintas regiones de nuestro país, lo que dificultad la comparación de su calidad asistencial. Objetivo: Seleccionar y definir una lista consensuada de indicadores de calidad aplicable a todas las unidades de transporte, especializadas o no, a nivel nacional. Material y métodos Realización de una propuesta inicial de indicadores por el comité coordinador con representantes del transporte especializado de nuestro país. Valoración del listado por especialistas en transporte de las unidades participantes y los grupos de trabajo de SECIP y SENeo. Selección de los indicadores mediante el método Delphi según su relevancia y factibilidad. Resultados El listado inicial incluyó 35 posibles indicadores. Fueron valorados por 22 especialistas pertenecientes a 7 unidades de transporte. En una primera fase se eligieron por consenso 4 indicadores, que pasaron directamente al listado definitivo. Se enviaron a los encuestados los resultados del resto de indicadores y las observaciones realizadas por los participantes, y tras ello se realizó una segunda valoración, en la que alcanzaron un consenso aceptable otros 11 indicadores. Tras la elaboración del listado, se estableció de forma consensuada la definición final de cada indicador elegido. Conclusiones Utilizando un sistema de búsqueda de consenso, definimos una lista de 15 indicadores comunes, que podría ser utilizada por las unidades especializadas de nuestro país y personal asistencial no especializado que realiza traslados pediátricos. Permitirá evaluar el rendimiento individual y comparar las diferentes unidades para encontrar oportunidades de mejora y asegurar la máxima calidad durante el transporte.
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- 2021
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34. A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study
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Guérin, C., Beuret, P., Constantin, J. M., Bellani, G., Garcia-Olivares, P., Roca, O., Meertens, J. H., Maia, P. Azevedo, Becher, T., Peterson, J., Larsson, A., Gurjar, M., Hajjej, Z., Kovari, F., Assiri, A. H., Mainas, E., Hasan, M. S., Morocho-Tutillo, D. R., Baboi, L., Chrétien, J. M., François, G., Ayzac, L., Chen, L., Brochard, L., Mercat, A., Hajjej, Zied, Sellami, Walid, Ferjani, M., Gurjar, Mohan, Assiri, Amer, Al Bshabshe, Ali, Almekhlafi, Ghaleb, Mandourah, Yasser, Hasan, Mohd Shahnaz, Rai, Vineya, Marzida, M., Corcoles Gonzalez, Virgilio, Sanchez Iniesta, Rafael, Garcia, Pablo, Garcia-Montesinos de la Peña, Manuel, Garcia Herrera, Adriana, Roca, Oriol, Garcia-de-Acilu, Marina, Masclans Enviz, Joan Ramon, Mancebo, Jordi, Heili, Sarah, Artigas Raventos, Antonio, Blanch Torra, LluÃs, Roche-Campo, Ferran, Rialp, Gemma, Forteza, Catalina, Berrazueta, Ana, Martinez, Esther, Penuelas, Oscar, Jara-Rubio, Ruben, Mallat, Jihad, Thevenin, D., Zogheib, Elie, Mercat, Alain, Levrat, Albrice, Porot, Veronique, Bedock, B., Grech, Ludovic, Plantefeve, Gaetan, Badie, Julio, Besch, Guillaume, Pili-Floury, Sébastien, Guisset, Olivier, Robine, Adrien, Prat, Gwenael, Doise, Jean-Marc, Badet, Michel, Thouret, J. M., Just, Bernard, Perbet, Sébastien, Lautrette, Alexandre, Souweine, B., Chabanne, Russell, Danguy des Déserts, Marc, Rigaud, Jean-Philippe, Marchalot, Antoine, Rigaud, J. P., Bele, Nicolas, Beague, Sébastien, Hours, Sandrine, Marque, Sophie, Durand, Michel, Payen, J. F., Stoclin, Annabelle, Gaffinel, Alain, Winer, Arnaud, Chudeau, Nicolas, Tirot, Patrice, Thyrault, Martial, Paulet, Rémi, Thyrault, M., Aubrun, Frederic, Guerin, Claude, Floccard, Bernard, Rimmele, T., Argaud, Laurent, Hernu, Romain, Crozon Clauzel, Jullien, Wey, Pierre-François, Bourdin, Gael, Pommier, C., Cueuille, NadÃge, de Varax, null, Marchi, Elisa, Papazian, L., Jochmans, Sebastien, Monchi, M., Jaber, Samir, de Jong, Audrey, Moulaire, Valerie, Capron, Matthieu, Jarrige, L., Barberet, Guillaume, Lakhal, Karim, Rozec, B., Dellamonica, Jean, Robert, Alexandre, Bernardin, G., Danin, Pierre-Eric, Raucoules, M., Runge, Isabelle, Foucrier, Arnaud, Hamada, Sophie, Tesniere, Antoine, Fromentin, Mélanie, Samama, C. M., Mira, Jean-Paul, Diehl, Jean-Luc, Mekontso Dessap, Armand, Arbelot, Charlotte, Demoule, Alexandre, Roche, Anne, Similowski, T., Ricard, Jean-Damien, Gaudry, Stéphane, Dreyfuss, D., de Montmolin, Etienne, da Silva, Daniel, Verdiere, B., Ardisson, Fanny, Lemiale, Virginie, Azoulay, Elie, Bruel, Cédric, Tiercelet, Kelly, Fartoukh, Muriel, Voiriot, Guillaume, Hoffmann, Clement, Leclerc, T., Thille, Arnaud, Robert, Réné, Beuret, Pascal, Beduneau, Gaëtan, Beuzelin, Marion, Tamion, F., Morel, Jérôme, Tremblay, Aymeric, Molliex, S., Amal, Jean-Michel, Meaudre, Eric, Goutorbe, Philippe, Laffon, Marc, Gros, Antoine, Nica, Alexandru, Barjon, Genevieve, Dahyot-Fizelier, Claire, Imzi, Nadia, Gally, Josette, Real, null, Sauneuf, Bertrand, Souloy, Xavier, Girbes, Armand, Tuinman, Pieter Roel, Schultz, Marcus, Winters, Tineke, Mijzen, Lisa, Roekaerts, P. M. H. J., Vermeijden, Wytze, Beishuizen, Albertus, Trof, R., Corsten, Stijn, Kesecioglu, Jozef, Meertens, John, Dieperink, Wim, Pickers, Peter, Roovers, Noortje, Maia, Paulo, Duque, Melanie, Rua, Fernando, Pereira de Figueired, António Manuel, Ramos, Armindo, Fragoso, Elsa, Azevedo, Pilar, Gouveia, Joao, Costa E. Silva, Zélia, Silva, Goncalo, Chaves, Susana, Nobrega, J. J., Lopes, LuÃs, Valerio, Bernardino, Araujo, Ana Carolina, de Freitas, Paulo Telles, Bouw, Maria Jose, Melao, Maria, Granja, C., Marcal, Paulo, Fernandes, Antero, Joao, Gonçalves Pereira, Maia, DionÃsio Faria, Spadaro, Savino, Volta, Carlo Alberto, Bellani, Giacomo, Citerio, G., Mauri, Tommaso, Alban, Laura, Pesenti, A., Mistraletti, Giovanni, Formenti, Paolo, Tommasino, C., Tardini, Francesca, Fumagalli, R., Colombo, Riccardo, Fossali, Tommaso, Catena, E., Todeschini, Manuel, Gnesin, Paolo, Cracchiolo, Andrea Neville, Palma, Daniela, Tetamo, R., Albiero, Daniela, Costantini, Elena, Raimondi, F., Coppadoro, Andrea, Vascotto, Ettore, Lusenti, F., Becher, Tobias, Schädler, Dirk, Weiler, N., Karagiannidis, Christian, Petersson, Johan, Konrad, D., Kawati, Rafael, Wessbergh, Joanna, Valtysson, J., Rockstroh, Matthias, Borgstrom, Sten, Larsson, Niklas, Thunberg, J., Camsooksai, Julie, Briggs, null, Kovari, Ferenc, Cuesta, J., Anwar, Sibs, O’Brien, B., Barberis, Luigi, Sturman, J., Mainas, Efstratios, Karatzas, S., Piza, Petr, Sottiaux, Thierry, Adam, J. F., Gawda, Ryszard, Gawor, Maen, Alqdah, M., Cohen, D., Brochard, Laurent, Baker, A., Ñamendys-Silva, Silvio Antonio, Garcia-Guillen, Francisco Javier, Morocho Tutillo, Diego Rolando, Jibaja Vega, Manuel, Zakalik, Graciela, Pagella, Gonzalo, Marengo, J., KARLI, Mélanie, Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL), Université de Lyon, Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Génétique, Reproduction et Développement (GReD ), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Hospital General Universitario 'Gregorio Marañón' [Madrid], Vall d'Hebron University Hospital [Barcelona], CIBER de Epidemiología y Salud Pública (CIBERESP), University Medical Center Groningen [Groningen] (UMCG), Centro Hospitalar do Porto, Karolinska University Hospital [Stockholm], Karolinska Institutet [Stockholm], Uppsala University, University of Malaya [Kuala Lumpur, Malaisie], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Keenan Research Centre of the Li Ka Shing Knowledge Institute [Toronto], Université d'Angers - Faculté de médecine (UA UFR Médecine), Université d'Angers (UA)-Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Other departments, Intensive Care Medicine, ACS - Diabetes & metabolism, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation, Critical Care, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), University of Malaya = Universiti Malaya [Kuala Lumpur, Malaisie] (UM), Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-IFR10, PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Université d'Angers (UA), Guã©rin, C, Beuret, P, Constantin, J, Bellani, G, Garcia-Olivares, P, Roca, O, Meertens, J, Maia, P, Becher, T, Peterson, J, Larsson, A, Gurjar, M, Hajjej, Z, Kovari, F, Assiri, A, Mainas, E, Hasan, M, Morocho-Tutillo, D, Baboi, L, Chrã©tien, J, Franã§ois, G, Ayzac, L, Chen, L, Brochard, L, Mercat, A, Sellami, W, Ferjani, M, Al Bshabshe, A, Almekhlafi, G, Mandourah, Y, Rai, V, Marzida, M, Corcoles Gonzalez, V, Sanchez Iniesta, R, Garcia, P, Garcia-Montesinos de la Peña, M, Garcia Herrera, A, Garcia-de-Acilu, M, Masclans Enviz, J, Mancebo, J, Heili, S, Artigas Raventos, A, Blanch Torra, L, Roche-Campo, F, Rialp, G, Forteza, C, Berrazueta, A, Martinez, E, Penuelas, O, Jara-Rubio, R, Mallat, J, Thevenin, D, Zogheib, E, Levrat, A, Porot, V, Bedock, B, Grech, L, Plantefeve, G, Badie, J, Besch, G, Pili-Floury, S, Guisset, O, Robine, A, Prat, G, Doise, J, Badet, M, Thouret, J, Just, B, Perbet, S, Lautrette, A, Souweine, B, Chabanne, R, Danguy des Déserts, M, Rigaud, J, Marchalot, A, Bele, N, Beague, S, Hours, S, Marque, S, Durand, M, Payen, J, Stoclin, A, Gaffinel, A, Winer, A, Chudeau, N, Tirot, P, Thyrault, M, Paulet, R, Aubrun, F, Guerin, C, Floccard, B, Rimmele, T, Argaud, L, Hernu, R, Crozon Clauzel, J, Wey, P, Bourdin, G, Pommier, C, Cueuille, N, de Varax, N, Marchi, E, Papazian, L, Jochmans, S, Monchi, M, Jaber, S, de Jong, A, Moulaire, V, Capron, M, Jarrige, L, Barberet, G, Lakhal, K, Rozec, B, Dellamonica, J, Robert, A, Bernardin, G, Danin, P, Raucoules, M, Runge, I, Foucrier, A, Hamada, S, Tesniere, A, Fromentin, M, Samama, C, Mira, J, Diehl, J, Mekontso Dessap, A, Arbelot, C, Demoule, A, Roche, A, Similowski, T, Ricard, J, Gaudry, S, Dreyfuss, D, de Montmolin, E, da Silva, D, Verdiere, B, Ardisson, F, Lemiale, V, Azoulay, E, Bruel, C, Tiercelet, K, Fartoukh, M, Voiriot, G, Hoffmann, C, Leclerc, T, Thille, A, Robert, R, Beduneau, G, Beuzelin, M, Tamion, F, Morel, J, Tremblay, A, Molliex, S, Amal, J, Meaudre, E, Goutorbe, P, Laffon, M, Gros, A, Nica, A, Barjon, G, Dahyot-Fizelier, C, Imzi, N, Gally, J, Real, N, Sauneuf, B, Souloy, X, Girbes, A, Tuinman, P, Schultz, M, Winters, T, Mijzen, L, Roekaerts, P, Vermeijden, W, Beishuizen, A, Trof, R, Corsten, S, Kesecioglu, J, Dieperink, W, Pickers, P, Roovers, N, Duque, M, Rua, F, Pereira de Figueired, A, Ramos, A, Fragoso, E, Azevedo, P, Gouveia, J, Costa E. Silva, Z, Silva, G, Chaves, S, Nobrega, J, Lopes, L, Valerio, B, Araujo, A, de Freitas, P, Bouw, M, Melao, M, Granja, C, Marcal, P, Fernandes, A, Joao, G, Maia, D, Spadaro, S, Volta, C, Citerio, G, Mauri, T, Alban, L, Pesenti, A, Mistraletti, G, Formenti, P, Tommasino, C, Tardini, F, Fumagalli, R, Colombo, R, Fossali, T, Catena, E, Todeschini, M, Gnesin, P, Cracchiolo, A, Palma, D, Tetamo, R, Albiero, D, Costantini, E, Raimondi, F, Coppadoro, A, Vascotto, E, Lusenti, F, Schã¤dler, D, Weiler, N, Karagiannidis, C, Petersson, J, Konrad, D, Kawati, R, Wessbergh, J, Valtysson, J, Rockstroh, M, Borgstrom, S, Larsson, N, Thunberg, J, Camsooksai, J, Briggs, N, Cuesta, J, Anwar, S, O’Brien, B, Barberis, L, Sturman, J, Karatzas, S, Piza, P, Sottiaux, T, Adam, J, Gawda, R, Gawor, M, Alqdah, M, Cohen, D, Baker, A, Ñamendys-Silva, S, Garcia-Guillen, F, Morocho Tutillo, D, Jibaja Vega, M, Zakalik, G, Pagella, G, and Marengo, J
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ARDS ,RECEIVING MECHANICAL VENTILATION ,Epidemiology ,medicine.medical_treatment ,cross-sectional studies ,RESPIRATORY-DISTRESS-SYNDROME ,vrouwelijk ,buikligging ,Critical Care and Intensive Care Medicine ,respiratory distress syndrome, adult/therapy ,law.invention ,Positive-Pressure Respiration ,Prone position ,0302 clinical medicine ,Mechanical ventilation ,prospectieve studies ,Randomized controlled trial ,law ,middle aged ,Medicine ,FAILURE ,adult/therapy ,humans ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,RANDOMIZED CONTROLLED-TRIAL ,respiratory distress syndrome ,3. Good health ,cross-sectionele studies ,ademnoodsyndroom ,aged ,female ,SURVIVAL ,middelbare leeftijd ,medicine.medical_specialty ,Pain medicine ,positieve druk uitademing ,NO ,03 medical and health sciences ,male ,mensen ,Anesthesiology ,ouderen ,METAANALYSIS ,business.industry ,MORTALITY ,030208 emergency & critical care medicine ,mannelijk ,CARE ,medicine.disease ,prospective studies ,EVOLUTION ,body regions ,030228 respiratory system ,Emergency medicine ,Observational study ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Introduction: While prone positioning (PP) has been shown to improve patient survival in moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of application of PP in clinical practice still appears low.Aim: This study aimed to determine the prevalence of use of PP in ARDS patients (primary endpoint), the physiological effects of PP, and the reasons for not using it (secondary endpoints).Methods: The APRONET study was a prospective international 1-day prevalence study performed four times in April, July, and October 2016 and January 2017. On each study day, investigators in each ICU had to screen every patient. For patients with ARDS, use of PP, gas exchange, ventilator settings and plateau pressure (Pplat) were recorded before and at the end of the PP session. Complications of PP and reasons for not using PP were also documented. Values are presented as median (1st-3rd quartiles).Results: Over the study period, 6723 patients were screened in 141 ICUs from 20 countries (77% of the ICUs were European), of whom 735 had ARDS and were analyzed. Overall 101 ARDS patients had at least one session of PP (13.7%), with no differences among the 4 study days. The rate of PP use was 5.9% (11/187), 10.3% (41/399) and 32.9% (49/149) in mild, moderate and severe ARDS, respectively (P = 0.0001). The duration of the first PP session was 18 (16-23) hours. Measured with the patient in the supine position before and at the end of the first PP session, PaO2/FIO2 increased from 101 (76-136) to 171 (118-220) mmHg (P = 0.0001) driving pressure decreased from 14 [11-17] to 13 [10-16] cmH(2)O (P = 0.001), and Pplat decreased from 26 [23-29] to 25 [23-28] cmH(2)O (P = 0.04). The most prevalent reason for not using PP (64.3%) was that hypoxemia was not considered sufficiently severe. Complications were reported in 12 patients (11.9%) in whom PP was used (pressure sores in five, hypoxemia in two, endotracheal tube-related in two ocular in two, and a transient increase in intracranial pressure in one).Conclusions: In conclusion, this prospective international prevalence study found that PP was used in 32.9% of patients with severe ARDS, and was associated with low complication rates, significant increase in oxygenation and a significant decrease in driving pressure.
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- 2018
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35. Importance of specialized paediatric and neonatal transport. Current situation in Spain: Towards a more equitable and universal future
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Raquerl Jordán Lucas, Nieves de Lucas García, Yolanda Ballesteros Diez, Alberto Salas Ballestín, Raquel Rodríguez Merlo, Laura Sánchez García, Nuria Millán García Del Real, Institut Català de la Salut, [Millán García Del Real N] Servicio de Emergencias Médicas Pediátricas, Cataluña, España. Unidad de Cuidados Intensivos Pediátricos, Hospital San Juan de Dios, Cataluña, España. Grupo de Estabilización y Transporte del Niño y Neonato Crítico de la Sociedad Española de Cuidados Intensivos Pediátricos (SECIP). [Sánchez García L] Servicio de Neonatología del Hospital Universitario La Paz, Madrid, España. Equipo de Transporte Neonatal de la Comunidad de Madrid, Madrid, España. Grupo de Transporte Neonatal de la Sociedad Española de Neonatología, España. [Ballesteros Diez Y] Servicio de Urgencias del Hospital Universitario Cruces, Bilbao, España. Grupo de trabajo de Paciente Crítico de la Sociedad Española de Urgencias de Pediatría. [Rodríguez Merlo R] SUMMA112 Madrid, Madrid, España. Grupo de Emergencias y Urgencias Pediátricas de la Sociedad Española de Medicina de Emergencias. [Salas Ballestín A] Grupo de Estabilización y Transporte del Niño y Neonato Crítico de la Sociedad Española de Cuidados Intensivos Pediátricos (SECIP). Unidad de Transporte Pediátrico de Baleares, Islas Baleares, España. Unidad de Cuidados Intensivos Pediátricos del Hospital Universitario Son Espases, Palma de Mallorca, España. [Jordán Lucas R] Servei de Neonatologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grupo de Transporte Neonatal de la Sociedad Española de Neonatología, and Vall d'Hebron Barcelona Hospital Campus
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media_common.quotation_subject ,Paediatric transport ,Neonatologia - Espanya ,Infants nadons - Transport - Espanya ,Pediatrics ,RJ1-570 ,law.invention ,Resource (project management) ,law ,Health Care Facilities, Manpower, and Services::Health Services::Community Health Services::Child Health Services [HEALTH CARE] ,medicine ,Quality (business) ,Function (engineering) ,media_common ,instalaciones, servicios y personal de asistencia sanitaria::servicios de salud::servicios médicos de urgencia::transporte de pacientes [ATENCIÓN DE SALUD] ,personas::Grupos de Edad::lactante::recién nacido [DENOMINACIONES DE GRUPOS] ,Persons::Age Groups::Infant::Infant, Newborn [NAMED GROUPS] ,medicine.disease ,Intensive care unit ,Continuous training ,Neonatal transport ,Variety (cybernetics) ,Health Care Facilities, Manpower, and Services::Health Services::Emergency Medical Services::Transportation of Patients [HEALTH CARE] ,Critical care ,instalaciones, servicios y personal de asistencia sanitaria::servicios de salud::Servicios de Salud Comunitaria::Servicios de Salud del Niño [ATENCIÓN DE SALUD] ,Homogeneous ,Pediatrics, Perinatology and Child Health ,Business ,Medical emergency ,Interfacility transport - Abstract
Transporte neonatal; Transporte interhospitalario; Cuidados críticos Neonatal transport; Interfacility transport; Critical care Transport neonatal; Transport interhospitalari; Cures crítiques El transporte pediátrico y neonatal especializado es un recurso útil y esencial en el traslado interhospitalario de estos pacientes. Permite acercar los recursos materiales y personales de una unidad de cuidados intensivos a los hospitales comarcales donde se pueda encontrar el paciente. Los beneficios de estos equipos están muy bien demostrados en la literatura. Estas unidades deberían formar parte de los sistemas de emergencias, al mismo tiempo que sería recomendable que estuvieran constituidas por personal integrado en los hospitales terciarios con el fin de mantener las habilidades y competencias necesarias. El equipo, compuesto por médicos, enfermeros y técnicos de emergencias sanitarias, tiene que dominar tanto la fisiopatología del transporte como la del paciente crítico en este rango de edad. Es importante una alta calidad tanto humana como asistencial, por lo que la formación continuada y el reciclaje periódico serán imprescindibles para poder cumplir correctamente con los indicadores de calidad en transporte. Así mismo, es fundamental contar con vehículos propios y adaptados a su función, que permitan llevar la gran variedad de material necesario, así como la electromedicina que se requiere. Sin embargo, en España este modelo de transporte pediátrico y neonatal no está estandarizado y por lo tanto no es homogéneo: existen diferentes modelos que no siempre aportan una adecuada calidad, siendo necesaria la implantación de unidades especializadas en todo el país para garantizar un transporte sanitario de calidad a cualquier niño o neonato crítico. Specialized paediatric and neonatal transport is a useful and essential resource in the interhospital transfer of these patients. It allows bringing the material and personal resources of an intensive care unit closer to the regional hospitals where the patient can be found. The benefits of these teams are very well demonstrated in the literature. These units should be part of the emergency systems, while it would be recommended that they would be staff integrated in the tertiary hospitals, in order to maintain the necessary skills and competencies. The team, made up of physicians, nurses and emergency medical technicians, must master both the pathophysiology of transport and that of the critical patient in this age range. A high-quality of both human and care is important, so continuous training and periodic recycling will be essential to be compliant with the quality indicators in transport. Likewise, it is essential to have specific vehicles adapted to this function, which allow carrying the wide variety of necessary material, as well as the electromedicine that is required. However, in Spain this paediatric and neonatal transport model is not standardized and, therefore, is not homogeneous: there are different models that do not always provide adequate quality, making it necessary to implement specialized units throughout the country to guarantee sanitary transport quality to any critical child or neonate.
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- 2021
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36. Prática de atividade física e esportiva em estudantes universitários: realização, estágios de mudança de comportamento e barreiras. Um estudo realizado na Universidade Federal do Espírito Santo
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PINTO, S. V., CORTE-REAL, N., PEREZ, A.J., Paulo Castelar Perim, and MENANDRO, P. R. M.
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Universitários [PALAVRAS-CHAVE] ,exercício ,atividade física - Abstract
Made available in DSpace on 2018-08-01T23:41:50Z (GMT). No. of bitstreams: 1 tese_9886_Dissertacao_PRATICA DE ATIVIDADE FISICA E ESPORTIVA EM ESTUDANTES UNIVERSITARIOS.pdf: 1351198 bytes, checksum: 756bb6e607fce29098cb72d29c957780 (MD5) Previous issue date: 2017-03-08 RESUMO Dada a importância da atividade física regular para a saúde e a constatação do estilo de vida pouco ativo dos jovens adultos na atualidade, o objetivo deste estudo foi analisar, em função do sexo e da idade: i) a natureza e a frequência das atividades físicas e práticas esportivas realizadas pelos universitários; ii) as barreiras impeditivas para engajar-se ou não em atividades físicas e os Estágios de Mudança de Comportamento - EMC - em que os acadêmicos se situam de acordo com o Modelo Transteórico - MTT. O trabalho consta de dois artigos e um relato de experiência tendo como participantes estudantes da Universidade Federal do Espírito Santo UFES, de diferentes cursos, tendo sido utilizado, para coleta de dados, uma adaptação para o português do Brasil de um inventário de comportamentos relacionados com a Saúde, utilizado em Portugal por Corte-Real et al. (2004, 2008) em estudos similares. No 1º estudo, foram investigados 164 estudantes do Curso Psicologia e no 2º estudo participaram 1697 estudantes de diferentes Cursos. As idades variavam entre 18 e 29 anos (média 21,7), sendo 60 % do sexo feminino e 40 % do sexo masculino. Os resultados mostraram, na amostra global, que 44,5 % dos universitários não praticavam esportes, 47,6 % não realizam nenhuma atividade física vigorosa e 32,7% não faziam atividades físicas moderadas semanalmente. Por outro lado, não chegava a 1/3 os que praticavam de forma regular tanto esporte como atividades físicas vigorosas. Constatou-se uma tendência no sentido de as mulheres e os mais jovens serem menos ativos fisicamente, sendo a falta de tempo a principal barreira mencionada pelos inquiridos. Quanto aos estágios de mudança de comportamento, verificou-se que apenas 29,3% dos respondentes encontrava-se no estágio de manutenção, referente aos que se exercitam regularmente há mais de 6 meses. A análise dos EMC sugere, ainda, que apenas uma pequena parcela dos estudantes (7%) demonstrou não ter intenção de adotar um comportamento fisicamente ativo, se posicionando no estágio de pré-contemplação. Isso indica que uma grande parte da população universitária não é fisicamente ativa, porém está posicionada nos estágios de contemplação e de preparação, pelo que poderia mudar sua atitude se fosse estimulada, por exemplo, com projetos semelhantes aos descritos no relato de experiência. Tais estímulos podem levar os jovens à percepção de que é possível gerir melhor o seu tempo e que podem investir em atividades físicas e esportivas sem prejuízo dos estudos e com ganhos em termos de saúde.
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- 2017
37. Teachers and parents together: developing children's resilience
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Miljević-Riđički, Renata, Bouillet, Dejana, Cefai Carmel, and Blanch Gelabert, S., Edo, M., Martinez-Minguez, L., Real, N., Karlsson Lohmander, M., Einarsdottir, J., Singer, E.
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early childhood ,resilience ,parents' manual ,resilience curriculum ,development - Abstract
The main aim is to present key aspect of the project "Resilience Curriculum for Early and Primary Schools in Europe" (RESCUR) which is carried out in the frame of the EU Comenius Multilateral Project. Along with the curriculum, the parent's manual has been developed as well.
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- 2015
38. Protocol for volume correlative light X-ray and electron microscopy of endothelial cells in mouse tissue.
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Reglero-Real N, Pérez-Gutiérrez L, Saleeb RS, Nourshargh S, Collinson L, and Yoshimura A
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- Animals, Mice, X-Ray Microtomography methods, Microscopy methods, Endothelial Cells ultrastructure, Endothelial Cells cytology, Microscopy, Electron methods
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Correlative light and electron microscopy (CLEM) greatly facilitate capturing the ultrastructure of spatially and/or temporally rare events. Here, we present a protocol for targeting regions of interests (ROIs) in tissue endothelial cells (ECs) using X-ray micro-computed tomography (μCT). We describe steps for ROI targeting guided by vasculature patterns and positions of EC nuclei visualized by light and X-ray microscopy. The protocol is applicable to thin or translucent tissues that contain defined landmarks visible in both light and X-ray microscopy. For complete details on the use and execution of this protocol, please refer to Reglero-Real et al.
1 ., Competing Interests: Declaration of interests The authors declare no competing interests., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)- Published
- 2024
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39. Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues.
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Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L, Golding M, Blacksell IA, Giblin MJ, Jaworska E, Bishop CL, Voisin MB, Gaston-Massuet C, Fossati-Jimack L, Pitzalis C, Cooper D, Nightingale TD, Lopez-Otin C, Lewis MJ, and Nourshargh S
- Subjects
- Animals, Humans, Mice, Cell Adhesion, Neutrophils metabolism, Neutrophils immunology, Cellular Senescence, Inflammation metabolism, Inflammation pathology, Endothelial Cells metabolism, Chemokine CXCL1 metabolism, Chemokine CXCL1 genetics
- Abstract
Cellular senescence is a hallmark of advanced age and a major instigator of numerous inflammatory pathologies. While endothelial cell (EC) senescence is aligned with defective vascular functionality, its impact on fundamental inflammatory responses in vivo at single-cell level remain unclear. To directly investigate the role of EC senescence on dynamics of neutrophil-venular wall interactions, we applied high resolution confocal intravital microscopy to inflamed tissues of an EC-specific progeroid mouse model, characterized by profound indicators of EC senescence. Progerin-expressing ECs supported prolonged neutrophil adhesion and crawling in a cell autonomous manner that additionally mediated neutrophil-dependent microvascular leakage. Transcriptomic and immunofluorescence analysis of inflamed tissues identified elevated levels of EC CXCL1 on progerin-expressing ECs and functional blockade of CXCL1 suppressed the dysregulated neutrophil responses elicited by senescent ECs. Similarly, cultured progerin-expressing human ECs exhibited a senescent phenotype, were pro-inflammatory and prompted increased neutrophil attachment and activation. Collectively, our findings support the concept that senescent ECs drive excessive inflammation and provide new insights into the mode, dynamics, and mechanisms of this response at single-cell level., (© 2024. The Author(s).)
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- 2024
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40. Fine mapping and identification of candidate genes associated with powdery mildew resistance in melon ( Cucumis melo L.).
- Author
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Duan X, Yuan Y, Real N, Tang M, Ren J, Wei J, Liu B, and Zhang X
- Abstract
Powdery mildew (PM), a common disease of many major crop species, including melon ( Cucumis melo L.), affects plant growth and fruit quality and seriously reduces production. Using a combined morphological and molecular approach, we attribute the PM pathogen that naturally occurs in melon to Podosphaera xanthii , and specifically to physiological race 1. An investigation into the genetic basis of PM resistance in melon using the resistant accession 'PI 164637' and susceptible counterpart 'HDZ' reveals dominant inheritance of PM resistance at the seedling stage, supported by F
2 and backcross population segregation ratios. Adult plant assessments indicate a major gene with an additive effect for PM resistance. Bulk segregant analysis coupled with high-throughput sequencing identified a significant quantitative trait locus on chromosome 6 that is associated with PM resistance. Genetic mapping narrowed down the candidate region to 63.5 kb using InDel molecular markers, harboring 12 candidate genes. The marker chr06_indel_5 047 127 demonstrated high accuracy in screening PM resistance in an F2 segregating population and 30 inbred lines as natural populations. Functional annotation and expression analysis of candidate genes revealed that MYB transcription factor MELO3C006700, GATA transcription factor MELO3C028829 and heparanase-like protein MELO3C006697 are promising candidate genes for PM resistance in melon. The genetic architecture underlying this resistance in melon offers valuable insights for breeding programs, and the identified markers, especially chr06_indel_5 047 127, may enable practical applications for marker-assisted selection in developing PM-resistant melon varieties., Competing Interests: The authors declare no conflict of interest., (© The Author(s) 2024. Published by Oxford University Press on behalf of Nanjing Agricultural University.)- Published
- 2024
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41. Metabolic, transcriptomic, and genetic analyses of candidate genes for seed size in watermelon.
- Author
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Wang X, Yan W, Real N, Jia Y, Fu Y, Zhang X, You H, Cai Y, and Liu B
- Abstract
Seed size (SS) constitutes a pivotal trait in watermelon breeding. In this study, we present findings from an examination of two watermelon accessions, namely, BW85 and F211. Seeds from BW85 exhibited a significant enlargement compared to those of F211 at 13 days after pollination (DAP), with the maximal disparity in seed length and width manifesting at 17 DAP. A comprehensive study involving both metabolic and transcriptomic analyses indicated a significant enrichment of the ubiquinone and other terpenoid-quinone biosynthesis KEGG pathways. To detect the genetic region governing seed size, a BSA-seq analysis was conducted utilizing the F
2 (BW85 × F211) population, which resulted in the identification of two adjacent QTLs, namely, SS6.1 and SS6.2 , located on chromosomes 6. SS6.1 spanned from Chr06:4847169 to Chr06:5163486, encompassing 33 genes, while SS6.2 ranged from Chr06:5379337 to Chr06:5419136, which included only one gene. Among these genes, 11 exhibited a significant differential expression between BW85 and F211 according to transcriptomic analysis. Notably, three genes ( Cla97C06G113960 , Cla97C06G114180 , and Cla97C06G114000 ) presented a differential expression at both 13 and 17 DAP. Through annotation, Cla97C06G113960 was identified as a ubiquitin-conjugating enzyme E2, playing a role in the ubiquitin pathway that mediates seed size control. Taken together, our results provide a novel candidate gene influencing the seed size in watermelon, shedding light on the mechanism underlying seed development., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Wang, Yan, Real, Jia, Fu, Zhang, You, Cai and Liu.)- Published
- 2024
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42. EFAS fellowship program.
- Author
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Corte-Real N, Lopez-Capdevila L, and Samaila EM
- Abstract
Competing Interests: Declaration of Competing Interest None.
- Published
- 2024
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43. ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin.
- Author
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Cacho-Navas C, López-Pujante C, Reglero-Real N, Colás-Algora N, Cuervo A, Conesa JJ, Barroso S, de Rivas G, Ciordia S, Paradela A, D'Agostino G, Manzo C, Feito J, Andrés G, Molina-Jiménez F, Majano P, Correas I, Carazo JM, Nourshargh S, Huch M, and Millán J
- Subjects
- Animals, Mice, Humans, Epithelial Cells metabolism, Hepatocytes metabolism, Liver metabolism, Actin Cytoskeleton metabolism, Leukocytes metabolism, Cell Polarity, Actomyosin metabolism, Intercellular Adhesion Molecule-1 genetics, Intercellular Adhesion Molecule-1 metabolism
- Abstract
Epithelial intercellular adhesion molecule (ICAM)-1 is apically polarized, interacts with, and guides leukocytes across epithelial barriers. Polarized hepatic epithelia organize their apical membrane domain into bile canaliculi and ducts, which are not accessible to circulating immune cells but that nevertheless confine most of ICAM-1. Here, by analyzing ICAM-1_KO human hepatic cells, liver organoids from ICAM-1_KO mice and rescue-of-function experiments, we show that ICAM-1 regulates epithelial apicobasal polarity in a leukocyte adhesion-independent manner. ICAM-1 signals to an actomyosin network at the base of canalicular microvilli, thereby controlling the dynamics and size of bile canalicular-like structures. We identified the scaffolding protein EBP50/NHERF1/SLC9A3R1, which connects membrane proteins with the underlying actin cytoskeleton, in the proximity interactome of ICAM-1. EBP50 and ICAM-1 form nano-scale domains that overlap in microvilli, from which ICAM-1 regulates EBP50 nano-organization. Indeed, EBP50 expression is required for ICAM-1-mediated control of BC morphogenesis and actomyosin. Our findings indicate that ICAM-1 regulates the dynamics of epithelial apical membrane domains beyond its role as a heterotypic cell-cell adhesion molecule and reveal potential therapeutic strategies for preserving epithelial architecture during inflammatory stress., Competing Interests: CC, CL, NR, NC, AC, JC, SB, Gd, SC, AP, GD, CM, JF, GA, FM, PM, IC, JC, SN, MH, JM No competing interests declared, (© 2023, Cacho-Navas et al.)
- Published
- 2024
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44. Self-reported bruxism in patients with post-traumatic stress disorder.
- Author
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Solis ACO, Corchs F, Duran ÉP, Silva C, Del Real N, Araújo ÁC, Wang YP, and Lotufo-Neto F
- Subjects
- Humans, Self Report, Case-Control Studies, Facial Pain etiology, Facial Pain diagnosis, Bruxism complications, Bruxism diagnosis, Sleep Bruxism complications, Stress Disorders, Post-Traumatic epidemiology
- Abstract
Objective: The present study aimed to investigate the association between self-reported awake/sleep bruxism, and orofacial pain with post-traumatic stress disorder (PTSD)., Methods: A case-control study with a convenience sample was designed. Participants were recruited from a university-based Trauma Ambulatory. The diagnosis of PTSD was established through a clinical interview and the Structured Clinical Interview (SCID-I/P). Thirty-eight PTSD patients and 38 controls completed the Research Diagnostic Criteria for Temporomandibular Disorders Axis-II to categorize awake/sleep bruxism and orofacial pain. Following this, we performed a short clinical examination of the temporomandibular joint and extraoral muscles., Results: Adjusted logistic regression analysis showed that awake bruxism was associated with PTSD (OR = 3.38, 95% CI = 1.01-11.27, p = 0.047). Sleep bruxism was not associated with any covariate included in the model. In a Poisson regression model, PTSD (IRR = 3.01, 95% CI = 1.38-6.55, p = 0.005) and the muscle pain/discomfort (IRR = 5.12, 95% CI = 2.80-9.36, p < 0.001) were significant predictors for current orofacial pain., Conclusions: PTSD was associated with self-reported awake bruxism and low-intensity orofacial pain. These conditions were frequent outcomes in patients previously exposed to traumatic events., Clinical Relevance: We suggest including a two-question screening for bruxism in psychiatry/psychology interviews to improve under-identification and to prevent harmful consequences at the orofacial level., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
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- View/download PDF
45. Lipidome Profiling in Childhood Obesity Compared to Adults: A Pilot Study.
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Soria-Gondek A, Fernández-García P, González L, Reyes-Farias M, Murillo M, Valls A, Real N, Pellitero S, Tarascó J, Jenkins B, Galán M, Villarroya F, Koulman A, Corrales P, Vidal-Puig A, Cereijo R, and Sánchez-Infantes D
- Subjects
- Humans, Adult, Child, Pilot Projects, Lipidomics, Sphingomyelins, Phosphatidylcholines metabolism, Phosphatidylinositols, Pediatric Obesity
- Abstract
The objective is to assess the circulating lipidome of children with obesity before and after lifestyle intervention and to compare the data to the circulating lipidome of adults with obesity before and after bariatric surgery. Ten pediatric (PE) and thirty adult (AD) patients with obesity were prospectively recruited at a referral single center. The PE cohort received lifestyle recommendations. The AD cohort underwent bariatric surgery. Clinical parameters and lipidome were analyzed in serum before and after six months of metabolic intervention. The abundance of phosphatidylinositols in the PE cohort and phosphatidylcholines in the AD significantly increased, while O-phosphatidylserines in the PE cohort and diacyl/triacylglycerols in the AD decreased. Fifteen lipid species were coincident in both groups after lifestyle intervention and bariatric surgery. Five species of phosphatidylinositols, sphingomyelins, and cholesteryl esters were upregulated. Eight species of diacylglycerols, glycerophosphoglycerols, glycerophosphoethanolamines, and phosphatidylcholines were downregulated. Most matching species were regulated in the same direction except for two phosphatidylinositols: PI(O-36:2) and PI(O-34:0). A specific set of lipid species regulated after bariatric surgery in adult individuals was also modulated in children undergoing lifestyle intervention, suggesting they may constitute a core circulating lipid profile signature indicative of early development of obesity and improvement after clinical interventions regardless of individual age.
- Published
- 2023
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46. Mutations in CmVPS41 controlling resistance to cucumber mosaic virus display specific subcellular localization.
- Author
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Real N, Villar I, Serrano I, Guiu-Aragonés C, and Martín-Hernández AM
- Subjects
- Humans, Genes, Plant, Viral Proteins metabolism, Mutation genetics, Plant Diseases genetics, Cucumovirus genetics, Cytomegalovirus Infections genetics
- Abstract
Resistance to cucumber mosaic virus (CMV) in melon (Cucumis melo L.) has been described in several exotic accessions and is controlled by a recessive resistance gene, cmv1, that encodes a vacuolar protein sorting 41 (CmVPS41). cmv1 prevents systemic infection by restricting the virus to the bundle sheath cells, preventing viral phloem entry. CmVPS41 from different resistant accessions carries two causal mutations, either a G85E change, found in Pat-81 and Freeman's cucumber, or L348R, found in PI161375, cultivar Songwhan Charmi (SC). Here, we analyzed the subcellular localization of CmVPS41 in Nicotiana benthamiana and found differential structures in resistant and susceptible accessions. Susceptible accessions showed nuclear and membrane spots and many transvacuolar strands, whereas the resistant accessions showed many intravacuolar invaginations. These specific structures colocalized with late endosomes. Artificial CmVPS41 carrying individual mutations causing resistance in the genetic background of CmVPS41 from the susceptible variety Piel de Sapo (PS) revealed that the structure most correlated with resistance was the absence of transvacuolar strands. Coexpression of CmVPS41 with viral movement proteins, the determinant of virulence, did not change these localizations; however, infiltration of CmVPS41 from either SC or PS accessions in CMV-infected N. benthamiana leaves showed a localization pattern closer to each other, with up to 30% cells showing some membrane spots in the CmVPS41SC and fewer transvacuolar strands (reduced from a mean of 4 to 1-2) with CmVPS41PS. Our results suggest that the distribution of CmVPS41PS in late endosomes includes transvacuolar strands that facilitate CMV infection and that CmVPS41 re-localizes during viral infection., Competing Interests: Conflict of interest statement. None declared., (© American Society of Plant Biologists 2022. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2023
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47. Regions of the human renal artery: histomorphometric analysis.
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Mompeó-Corredera B, Hernández-Morera P, Castaño-González I, Quintana-Montesdeoca MDP, and Mederos-Real N
- Abstract
The renal artery is frequently involved in the pathogenesis of vasculorenal diseases, and it is a target in kidney surgery and therapeutic techniques for refractory hypertension. However, few detailed structural studies on the human renal artery have been conducted. Using histocytochemistry, immunohistochemistry, and quantitative image analysis, the wall thickness, structure, smooth muscle cells, extracellular matrix, and proportion of elastic tissue in the tunica media of main human renal arteries were used estimated. Ninety-six tissue samples were collected from sections of the right and left main renal arteries. The results showed that the renal artery changed from an elastic vessel in its proximal segment to a muscular artery in its distal part. A critical characteristic of the renal artery was the presence of longitudinal smooth muscle cell formations in the tunica adventitia of middle and distal segments but not in the proximal part of the artery. In addition, the tunica adventitia of the renal artery showed a rich vascularization and the presence of numerous nerves profiles. The artery's regional structural and morphometric features explain that a particular arterial pathology is more frequent in a specific vessel sector than in others. In addition, those characteristics could determine a different therapeutic response attending to the arterial sector.
- Published
- 2022
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48. EFAS Score - Validation of Portuguese Version by the Score Committee of the European Foot and Ankle Society (EFAS).
- Author
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Richter M, Agren PH, Besse JL, Coester M, Kofoed H, Maffulli N, Steultjens M, Côrte-Real N, and Dias R
- Subjects
- Ankle Joint, Humans, Portugal, Reproducibility of Results, Surveys and Questionnaires, Ankle surgery, Language
- Abstract
Background: The Score Committee of the European Foot and Ankle Society (EFAS) developed, validated, and published the EFAS Score in ten languages (English, German, French, Italian, Polish, Dutch, Swedish, Finnish, Turkish, Portuguese). From other languages under validation, the Portuguese version completed data acquisition and underwent further validation., Methods: The Portuguese version of the EFAS Score was developed and validated in three stages: 1) item (question) identification (completed during initial validation study), 2) item reduction and scale exploration (completed during initial validation study), 3) confirmatory analyses and responsiveness of Portuguese version (completed during initial validation study in nine other languages). The data were collected pre-operatively and post-operatively at a minimum follow-up of 3 months and mean follow-up of 6 months. Item reduction, scale exploration, confirmatory analyses and responsiveness were executed using classical test theory and item response theory., Results: The internal consistency was confirmed in the Portuguese version (Cronbach's Alpha 0.84). The Standard Error of Measurement (SEM) was 0.27 and is similar to other language versions. Between baseline and follow-up, 69.4% of patients showed an improvement on their EFAS score, with adequate responsiveness (effect size 0.64)., Conclusions: The Portuguese EFAS Score version was successfully validated in patients with a wide variety of foot and ankle pathologies. All score versions are freely available at www.efas.net., (Copyright © 2022 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2022
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49. [Consecutive Ankle Sprain Classification and Injury Systematization (CASCaIS), A New Lateral Ankle Sprain Classification Based on the Pivot Test: A Prospective Cohort Study].
- Author
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Guerra-Pinto F, Caetano J, Alçada R, Brito Camacho A, Pacheco J, Lacerda D, Alves-da-Silva T, Côrte-Real N, and Guimarães Consciência J
- Subjects
- Humans, Infant, Child, Preschool, Prospective Studies, Ankle Joint, Ankle Injuries diagnosis, Ankle Injuries complications, Sprains and Strains diagnosis, Sprains and Strains complications, Joint Instability diagnosis, Joint Instability complications
- Abstract
Introduction: The biggest challenge in the treatment of acute ankle sprain is the uncertainty of the prognosis. The traditional classifications have several interpretations and little correlation with prognosis. In this study we propose a new classification for acute ankle sprain only based on clinical criteria., Material and Methods: We prospectively evaluated all patients with an ankle sprain, aged between 18 and 45 years, admitted to a hospital during a 24 month period. The minimum follow-up period was 12 months. The sprains were classified, in the first few days (CASCaIS-Initial), according to autonomous gait capacity, inspection and palpation. After a few weeks (CASCaIS-Deferred), it was complemented with the mechanical evaluation of ligaments through the ankle pivot test., Results: Among the 49 patients who completed the follow-up, none of those who had a pivot-negative test progressed to chronic ankle instability (CAI). Nine of the 33 patients (27%) with a positive pivot progressed to CAI (p = 0.022). The evaluation of CASCaIS-Deferred demonstrated an association with CAI (p = 0.018)., Conclusion: This classification proved to be a simple, inexpensive, and reliable tool that clinicians can use to determine the prognosis of the sprain.
- Published
- 2022
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50. Prenatal Betamethasone Exposure and its Impact on Pediatric Type 1 Diabetes Mellitus: A Preliminary Study in a Spanish Cohort.
- Author
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Perna-Barrull D, Murillo M, Real N, Gomez-Muñoz L, Rodriguez-Fernandez S, Bel J, Puig-Domingo M, and Vives-Pi M
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- Adult, Betamethasone metabolism, Betamethasone therapeutic use, Case-Control Studies, Child, Child, Preschool, Cohort Studies, Diabetes Mellitus, Type 1 epidemiology, Female, Germany epidemiology, Glucocorticoids adverse effects, Glucocorticoids metabolism, Glucocorticoids therapeutic use, Humans, Pediatrics methods, Pediatrics statistics & numerical data, Pregnancy, Prenatal Exposure Delayed Effects epidemiology, Prenatal Exposure Delayed Effects etiology, Retrospective Studies, Betamethasone adverse effects, Prenatal Exposure Delayed Effects diagnosis
- Abstract
Background: Betamethasone, a glucocorticoid used to induce lung maturation when there is a risk of preterm delivery, can affect the immune system maturation and type 1 diabetes (T1D) incidence in the progeny. It has been described that prenatal betamethasone protects offspring from experimental T1D development. The main aim of this study was to evaluate the possible association between betamethasone prenatal exposure and T1D in humans. Research Design and Methods . A retrospective case-control study with a total of 945 children, including 471 patients with T1D and 474 healthy siblings, was performed. Participants were volunteers from the Germans Trias i Pujol Hospital and DiabetesCero Foundation. Parents of children enrolled in the study completed a questionnaire that included questions about weeks of gestation, preterm delivery risk, weight at birth, and prenatal betamethasone exposure of their children. Multiple logistic regression was used to detect the association between betamethasone exposure and T1D., Results: We compared T1D prevalence between subjects prenatally exposed or unexposed to betamethasone. The percent of children with T1D in the exposed group was 37.5% (21 of 56), and in the unexposed group was 49.52% (410 of 828) ( p = 0.139). The percentage of betamethasone-treated subjects with T1D in the preterm group (18.05%, 13 of 72) was significantly higher than that found in the control group (12.5%, 9 of 72) ( p = 0.003). The odds ratio for T1D associated with betamethasone in the univariate logistic regression was 0.59 (95% confidence interval, 0.33; 1.03 [ p = 0.062]) and in the multivariate logistic regression was 0.83 (95% confidence interval, 0.45; 1.52 [ p = 0.389])., Conclusions: The results demonstrate that the prenatal exposure to betamethasone does not increase T1D susceptibility, and may even be associated with a trend towards decreased risk of developing the disease. These preliminary findings require further prospective studies with clinical data to confirm betamethasone exposure effect on T1D risk., Competing Interests: The other authors report no conflicts of interest in this work., (Copyright © 2022 David Perna-Barrull et al.)
- Published
- 2022
- Full Text
- View/download PDF
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