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Byline: Preeti. Rawat, Ritika. Agrawal, Vijay. Bhaisare, Shweta. Walia, Neetu. Kori, Rishi. Gupta Purpose: To evaluate and compare the efficacy of autologous platelet-rich plasma (aPRP) eye drop and artificial tear [...]

Byline: Manushree. Gautam, Meenal. Soni, Vijay. Bhaisare, Preeti. Rawat, Shweta. Walia, Neetu. Kori Purpose: To study facial nerve palsy (FNP) in post-COVID-19-mucormycosis patients and its ocular complications, report different presentations [...]

Byline: Shweta. Walia, Vijay. Bhaisare, Preeti. Rawat, Neetu. Kori, Manushree. Sharma, Niti. Gupta, Shishir. Urdhwareshwar, Sanchiyka. Thakur, Niharika. Arya Purpose: Mucormycosis is a life-threatening infection that has made sudden comeback [...]

Byline: Preeti. Rawat, Archana. Bhange, Varun. Upadhyay, Vijay. Bhaisare, Shweta. Walia, Neetu. Kori Purpose: This purpose of this study was to find the association between severity of visual impairment and [...]

Background: Biogenic fabrication of metal oxide nanoparticles has been gaining interest over conventional methods. Biological methods make use of plant materials and microbial agents as reducing as well as capping agents. The present work reports the biosynthesis of ZnO NPs from agricultural wastes produced in every household. Objectives: A significant portion of municipal solid organic waste (MSOW) consists of agricultural waste. Utilization of this agricultural waste towards cleaning water of pathogens through the synthesis of nanoparticles has far-reaching implications, such as curbing soil pollution and water pollution. Methods: Preliminary confirmation was done by the visual formation of a pale yellow/dirty white precipitate of ZnO NPs. These were further characterized by different spectroscopic techniques, such as FT-IR, SEM, EDAX, and HRTEM. Results: The HRTEM study revealed that NPs obtained had sizes between 30-52 nm. Fabricated ZnO NPs were analyzed for their antibacterial activity by disk diffusion method, and they exhibited striking antibacterial activity against E. coli and bacillus subtilis. Conclusion: Exploring the potential of waste and its conversion into a value-added product is a novel step. ZnO nanoparticles were successfully synthesized from agricultural wastes through an environmentally friendly synthetic route, and the synthesized ZnO NPs were found to be potent in inhibiting the growth of bacteria.

The complications in liver functioning arising due to hepatic disorders are a major contributor of mortality worldwide, with transplantation being the only resort for patients with severe cases. Due to liver's direct role in drug metabolism, fabrication on functional liver tissue models is eventually becoming a necessity for high-throughput drug screening applications. Tissue engineering approaches could provide an answer to the drooping supply by allowing for the fabrication and printing of a fully operational, implantable, and sustainable liver tissues. Moreover, such bioengineered tissues can be made to resemble their native counterparts. 3D bioengineering strategies including 3D bioprinting and microfluidic-based liver-on-chip models stand out in this regard due to their potential to create physiologically relevant microenvironment/niches for the biofabricated tissues. Nonetheless, achieving vascularization in such bioengineered tissues is still considered one of the biggest bottlenecks for engineers. The incorporation of blood vessels made from endothelial cells (ECs) is addressed in vasculogenesis while angiogenesis investigates generating new vessels from preexisting vasculature. Overall, vascularization is essential for the survival, function, and integration of bioprinted liver tissues, making it a key focus area in the development of functional liver substitutes for regenerative medicine and drug testing applications. This review paper focuses on the opportunities and difficulties of performing vascularization and angiogenesis in 3D bioengineered-based liver tissue models. Particularly, this paper delves into aspects such as methods of bioengineering, bioinks used, analysis techniques, advantages, limitations, and prospects related to 3D bioengineered liver tissue models as well as vascular engineering in general.