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301 results on '"Ravaglia G."'

1. 615P Circulating tumor cells (CTC) gene expression and plasma androgen receptor (AR) copy number (CN) in cabazitaxel-treated metastatic castration-resistant prostate cancer (mCRPC)

Author

Gurioli, G., primary, Conteduca, V., additional, Brighi, N., additional, Scarpi, E., additional, Basso, U., additional, Fornarini, G., additional, Mosca, A., additional, Nicodemo, M., additional, Banna, G.L., additional, Lolli, C., additional, Schepisi, G., additional, Ravaglia, G., additional, Ulivi, P., additional, and De Giorgi, U., additional

Published
2021
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3. Riscoprire il bello dell’annoiarsi. Idee a confronto tra insegnanti sulla noia dei bambini

Author

Ravaglia, G, Villa, FV, Ravaglia, G, and Villa, F

Subjects
noia, insegnanti, M-PED/01 - PEDAGOGIA GENERALE E SOCIALE, alleanze, contesti, riscoperta
Abstract

In due focus group con le insegnanti della scuola primaria si è riflettuto sul tema della noia nei bambini. Molti sono gli spunti di riflessione emersi che hanno condotto le discussioni su numerose tematiche educative e sociali. La noia, dalle loro parole, si lega dunque al contesto in cui è immerso il bambino, ricco di stimoli e senza momenti “vuoti” e quindi al ruolo che ciascuno di noi ha nella società, ma anche ad un fattore motivazionale che spinge al di là del soffermarsi sul cosa fare. Riscoprire il bello della noia diviene una necessità avvertita poiché in grado di aprire spazi di pensiero, di libertà, di creatività e lentezza ai quali tutti i bambini dovrebbero avere diritto.

Published
2019

6. The association of ageing with calcium active hormone status in men

Author

Ravaglia, G., Forti, P., Pratelli, L., Maioli, F., Scali, C.R., Bonini, A.M., Tedioli, S., Marasti, N., Pizzoferrato, A., and Gasbarrini, G.

Subjects
Calcium metabolism -- Demographic aspects -- Physiological aspects, Alfacalcidol -- Demographic aspects -- Physiological aspects, Calcifediol -- Demographic aspects -- Physiological aspects, Vitamin D -- Demographic aspects -- Physiological aspects, Aged men -- Physiological aspects, Bones -- Density, Vitamin metabolism -- Demographic aspects -- Physiological aspects, Health, Psychology and mental health, Seniors, Social sciences, Physiological aspects, Demographic aspects
Abstract

G. RAVAGLIA, P. FORTI, L. PRATELLI, F. MAIOLI, C. R. SCALI, A. M. BONINI, S. TEDIOLI, N. MARASTI, A. PIZZOFERRATO, G. GASBARRINI We measured calcium regulating hormones and bone mineral [...]

Published
1994

10. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

Author

Lambert, J., Sleegers, K., Gonzalez-Perez, A., Ingelsson, M., Beecham, G., Hiltunen, M., Combarros, O., Bullido, M., Brouwers, N., Bettens, K., Berr, C., Pasquier, F., Richard, F., Dekosky, S., Hannequin, D., Haines, J., Tognoni, G., Fievet, N., Dartigues, J., Tzourio, C., Engelborghs, S., Arosio, B., Coto, E., De Deyn, P., Del Zompo, M., Mateo, I., Boada, M., Antunez, C., Lopez-Arrieta, J., Epelbaum, J., Schjeide, B., Frank-Garcia, A., Giedraitis, V., Helisalmi, S., Porcellini, E., Pilotto, A., Forti, P., Ferri, R., Delepine, M., Zelenika, D., Lathrop, M., Scarpini, E., Siciliano, G., Solfrizzi, V., Sorbi, S., Spalletta, G., Ravaglia, G., Valdivieso, F., Vepsalainen, S., Alvarez, V., Bosco, P., Mancuso, M., Panza, F., Nacmias, B., Bossu, P., Hanon, O., Piccardi, P., Annoni, G., Mann, D., Marambaud, P., Seripa, D., Galimberti, D., Tanzi, R., Bertram, L., Lendon, C., Lannfelt, L., Licastro, F., Campion, D., Pericak-Vance, M., Soininen, H., Van Broeckhoven, C., Alperovitch, A., Ruiz, A., Kamboh, M., and Amouyel, P.

Subjects
lipids (amino acids, peptides, and proteins)
Abstract

The only established genetic determinant of non-Mendelian forms of Alzheimer's disease (AD) is the epsilon4 allele of the apolipoprotein E gene (APOE). Recently, it has been reported that the P86L polymorphism of the calcium homeostasis modulator 1 gene (CALHM1) is associated with the risk of developing AD. In order to independently assess this association, we performed a meta-analysis of 7,873 AD cases and 13,274 controls of Caucasian origin (from a total of 24 centers in Belgium, Finland, France, Italy, Spain, Sweden, the UK, and the USA). Our results indicate that the CALHM1 P86L polymorphism is likely not a genetic determinant of AD but may modulate age of onset by interacting with the effect of the epsilon4 allele of the APOE gene.

Published
2010

12. Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations

Author

Lambert, J, Zelenika, D, Hiltunen, M, Chouraki, V, Combarros, O, Bullido, M, Tognoni, G, Fiévet, N, Boland, A, Arosio, B, Coto, E, Zompo, M, Mateo, I, Frank Garcia, A, Helisalmi, S, Porcellini, E, Pilotto, A, Forti, P, Ferri, R, Delepine, M, Scarpini, E, Siciliano, G, Solfrizzi, V, Sorbi, S, Spalletta, G, Ravaglia, G, Valdivieso, F, Alvarez, V, Bosco, P, Mancuso, M, Panza, F, Nacmias, B, Bossù, P, Piccardi, P, Annoni, G, Seripa, D, Galimberti, D, Licastro, F, Lathrop, M, Soininen, H, Amouyel, P, Bullido, MJ, Zompo, MD, ANNONI, GIORGIO, Amouyel, P., Lambert, J, Zelenika, D, Hiltunen, M, Chouraki, V, Combarros, O, Bullido, M, Tognoni, G, Fiévet, N, Boland, A, Arosio, B, Coto, E, Zompo, M, Mateo, I, Frank Garcia, A, Helisalmi, S, Porcellini, E, Pilotto, A, Forti, P, Ferri, R, Delepine, M, Scarpini, E, Siciliano, G, Solfrizzi, V, Sorbi, S, Spalletta, G, Ravaglia, G, Valdivieso, F, Alvarez, V, Bosco, P, Mancuso, M, Panza, F, Nacmias, B, Bossù, P, Piccardi, P, Annoni, G, Seripa, D, Galimberti, D, Licastro, F, Lathrop, M, Soininen, H, Amouyel, P, Bullido, MJ, Zompo, MD, ANNONI, GIORGIO, and Amouyel, P.

Abstract

Recent genome-wide association studies have identified 5 loci (BIN1, CLU, CR1, EXOC3L2, and PICALM) as genetic determinants of Alzheimer's disease (AD). We attempted to confirm the association between these genes and the AD risk in 3 contrasting European populations (from Finland, Italy, and Spain). Because CLU and CR1 had already been analyzed in these populations, we restricted our investigation to BIN1, EXO2CL3, and PICALM. In a total of 2816 AD cases and 2706 controls, we unambiguously replicated the association of rs744373 (for BIN1) and rs541458 (for PICALM) polymorphisms with the AD risk (odds ratio [OR] = 1.26, 95% confidence interval [CI] [1.15-1.38], p = 2.9 × 10-7, and OR = 0.80, 95% CI [0.74-0.88], p = 4.6 × 10-7, respectively). In a meta-analysis, rs597668 (EXOC3L2) was also associated with the AD risk, albeit to a lesser extent (OR = 1.19, 95% CI [1.06-1.32], p = 2.0 × 10-3). However, this signal did not appear to be independent of APOE. In conclusion, we confirmed that BIN1 and PICALM are genetic determinants of AD, whereas the potential involvement of EXOC3L2 requires further investigation. © 2011 Elsevier Inc.

Published
2011

16. Reply

Author

Ravaglia, G., primary, Forti, P., additional, Lucicesare, A., additional, Pisacane, N., additional, Rietti, E., additional, and Patterson, C., additional

Published
2008
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39. Dehydroepiandrosterone sulphate and dementia

Author

Ravaglia, G., primary, Forti, P., additional, Maioli, F., additional, Boschi, F., additional, De Ronchi, D., additional, Bernardi, M., additional, Pratelli, L., additional, Pizzoferrato, A., additional, and Cavalli, G., additional

Published
1998
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41. Nutritional status and dementia in oldest-old women

Author

Ravaglia, G., primary, De Ronchi, D., additional, Forti, P., additional, Maioli, F., additional, Cicognani, A., additional, Scali, C.R., additional, Pratelli, L., additional, Pizzoferrato, A., additional, Bernardi, M., additional, and Gasbarrini, G., additional

Published
1998
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