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501 results on '"Ravaglia, Claudia"'

1. High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study

Author

Anderson, Adam, Morgenthau, Adam, Gaser, Adrian, Vizel, Alexander, Speranskaya, Alexandra, Gerke, Alicia, Goksel, Altinisik, Undurraga, Alvaro, Sharma, Amita, Oh, Andrea, Leung, Ann, Larici, Anna Rita, Prasse, Antje, Mazzei, Antonietta, Morais, Antonio, Bhalla, Ashu, Del Rio, Belen, Jankharia, Bhavin, Elicker, Brett, Pereira, Carlos, Biegelman-Aubry, Catherine, White, Charles, Ravaglia, Claudia, Hsia, Connie, Schaefer-Prokop, Cornelia, Launay, David, Talwar, Deepak, Castillo, Diego, Patel, Divya, Israel-Biet, Dominique, Valeyre, Dominique, Britt, Edward James, Bargagli, Elena, Bendstrup, Elisabeth, Crouser, Elliott, Nossent, Esther, Shmelev, Eugeny, Porquera, Eva Carmona, Bonella, Francesco, Cohen-Aubart, Fleur, Jeny, Florence, Ferrara, Giovanni, Jin, Gong Yong, Robbie, Hasti, Prosch, Helmut, Sumikawa, Hiromitsu, Ling-Pei, Ho, Lee, Ho Yun, Strambu, Irina, Buendia-Roldan, Ivette, Grutters, Jan, Ryu, Jay, Swigris, Jeff, Miedema, Jelle, Goo, Jin Mo, Barnett, Joseph, Verschakelen, Johny, Goldin, Jonathan, Seo, Joon Beom, Enghelmayer, Juan, Mana, Juan, Behr, Juergen, Patterson, Karen, Antoniou, Katerina, Brown, Kevin, Fujimoto, Kiminori, Savale, Laurent, Maier, Lisa, Richeldi, Luca, Neto, Manuel Lessa Ribeiro, Humbert, Marc, Judson, Marc, Veltkamp, Marcel, Wilsher, Margaret, Molina, Maria, Otaola, Maria, Revel, Marie-Pierre, Silva, Mario, Drent, Marjolein, Schiebler, Mark, Wijsenbeek-Lourens, Marlies, Bonifazi, Martina, Remy-Jardin, Martine, Koslow, Matthew, Balter, Meyer, Kreuter, Michael, Thillai, Muhunthan, Hamzeh, Nabeel, Chaudhuri, Nazia, Mogulkoc, Nesrin, Todd, Nevins, Screaton, Nick, Goh, Nicole, Shah, Nirav, Obi, Ogugua, Shlobin, Oksana, Baranova, Olga, Bresser, Paul, Rottoli, Paula, Brillet, Pierre-Yves, Said-Hartley, Qonita, Borie, Raphael, Mostard, Remy, van Zyl-smit, Richard, Kairalla, Ronaldo, Egashira, Ryoko, Boussouar, Samia, Lee, Sang Min, Bhalla, Sanjeev, Tomassetti, Sara, Quadrelli, Silvia, Hart, Simon P, Danoff, Sonye, Rajan, Sujeet, Choi, Sun Mi, Copley, Susan, Kim, Tae Jung, Johkoh, Takeshi, Corte, Tamera, McLoud, Theresa, Wessendorf, Thomas, Alfaro, Tiago, Arai, Toru, Costabel, Ulrich, Vicens-Zygmunt, Vanesa, Poletti, Venerino, Cottin, Vincent, Vucinic, Violeta, Wuyts, Wim, van Es, Wouter, Jeong, Yeon Joo, Inoue, Yoshikazu, Desai, Sujal R, Sivarasan, Nishanth, Johannson, Kerri A, George, Peter M, Culver, Daniel A, Devaraj, Anand, Lynch, David A, Milne, David, Renzoni, Elisabetta, Nunes, Hilario, Sverzellati, Nicola, Spagnolo, Paolo, Baughman, Robert P, Yadav, Ruchi, Piciucchi, Sara, Walsh, Simon L F, Kouranos, Vasileios, and Wells, Athol U

Published
2024
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2. Detection and Early Referral of Patients With Interstitial Lung Abnormalities An Expert Survey Initiative

Author

Hunninghake, Gary M, Goldin, Jonathan G, Kadoch, Michael A, Kropski, Jonathan A, Rosas, Ivan O, Wells, Athol U, Yadav, Ruchi, Lazarus, Howard M, Abtin, Fereidoun G, Corte, Tamera J, de Andrade, Joao A, Johannson, Kerri A, Kolb, Martin R, Lynch, David A, Oldham, Justin M, Spagnolo, Paolo, Strek, Mary E, Tomassetti, Sara, Washko, George R, White, Eric S, Group, ILA Study, Abtin, Fereidoun, Antoniou, Katerina, Blackwell, Timothy, Brown, Kevin, Chung, Jonathan, Corte, Tamera, Crestani, Bruno, Crossno, Peter, Culver, Daniel, de Andrade, Joao, Deveraj, Anand, Flaherty, Kevin, Gudmundsson, Gunnar, Hatabu, Hiroto, Jacob, Joe, Johansson, Kerri, Kanne, Jeff, Kazerooni, Ella, Kolb, Martin, Lynch, David, Maher, Toby, Martinez, Fernando, Morais, Antonio, Nathan, Steven D, Noth, Imre, Oldham, Justin, Podolanczuk, Anna, Poletti, Venerino, Ravaglia, Claudia, Renzoni, Elizabetta, Richeldi, Luca, Rubin, Geoffrey, Ryerson, Chris, Sahoo, Debasis, Suh, Rob, Sverzellati, Nicola, Valeyre, Dominique, Walsh, Simon, and Washko, George

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Lung, Prevention, Cancer, Clinical Research, Biomedical Imaging, 4.2 Evaluation of markers and technologies, Disease Progression, Early Diagnosis, Female, Humans, Lung Diseases, Interstitial, Male, Pulmonologists, Radiologists, Referral and Consultation, Respiratory Function Tests, Surveys and Questionnaires, Tomography, X-Ray Computed, CT, fi brosis, interstitial lung abnormalities, interstitial lung disease, survey, ILA Study Group, fibrosis, Respiratory System, Cardiovascular medicine and haematology, Clinical sciences
Abstract

BackgroundInterstitial lung abnormalities (ILA) may represent undiagnosed early-stage or subclinical interstitial lung disease (ILD). ILA are often observed incidentally in patients who subsequently develop clinically overt ILD. There is limited information on consensus definitions for, and the appropriate evaluation of, ILA. Early recognition of patients with ILD remains challenging, yet critically important. Expert consensus could inform early recognition and referral.Research questionCan consensus-based expert recommendations be identified to guide clinicians in the recognition, referral, and follow-up of patients with or at risk of developing early ILDs?Study design and methodsPulmonologists and radiologists with expertise in ILD participated in two iterative rounds of surveys. The surveys aimed to establish consensus regarding ILA reporting, identification of patients with ILA, and identification of populations that might benefit from screening for ILD. Recommended referral criteria and follow-up processes were also addressed. Threshold for consensus was defined a priori as ≥ 75% agreement or disagreement.ResultsFifty-five experts were invited and 44 participated; consensus was reached on 39 of 85 questions. The following clinically important statements achieved consensus: honeycombing and traction bronchiectasis or bronchiolectasis indicate potentially progressive ILD; honeycombing detected during lung cancer screening should be reported as potentially significant (eg, with the Lung CT Screening Reporting and Data System "S-modifier" [Lung-RADS; which indicates clinically significant or potentially significant noncancer findings]), recommending referral to a pulmonologist in the radiology report; high-resolution CT imaging and full pulmonary function tests should be ordered if nondependent subpleural reticulation, traction bronchiectasis, honeycombing, centrilobular ground-glass nodules, or patchy ground-glass opacity are observed on CT imaging; patients with honeycombing or traction bronchiectasis should be referred to a pulmonologist irrespective of diffusion capacity values; and patients with systemic sclerosis should be screened with pulmonary function tests for early-stage ILD.InterpretationGuidance was established for identifying clinically relevant ILA, subsequent referral, and follow-up. These results lay the foundation for developing practical guidance on managing patients with ILA.

Published
2022

3. Lymphoproliferative Lung Disorders

Author

Poletti, Venerino, Piciucchi, Sara, Tomassetti, Sara, Asioli, Silvia, Dubini, Alessandra, Chilosi, Marco, Ravaglia, Claudia, Cottin, Vincent, editor, Richeldi, Luca, editor, Brown, Kevin, editor, and McCormack, Francis X., editor

Published
2023
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5. Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis

Author

Moore, Camille, Blumhagen, Rachel Z, Yang, Ivana V, Walts, Avram, Powers, Julie, Walker, Tarik, Bishop, Makenna, Russell, Pamela, Vestal, Brian, Cardwell, Jonathan, Markin, Cheryl R, Mathai, Susan K, Schwarz, Marvin I, Steele, Mark P, Lee, Joyce, Brown, Kevin K, Loyd, James E, Crapo, James D, Silverman, Edwin K, Cho, Michael H, James, Judith A, Guthridge, Joel M, Cogan, Joy D, Kropski, Jonathan A, Swigris, Jeffrey J, Bair, Carol, Kim, Dong Soon, Ji, Wonjun, Kim, Hocheol, Song, Jin Woo, Maier, Lisa A, Pacheco, Karin A, Hirani, Nikhil, Poon, Azin S, Li, Feng, Jenkins, R Gisli, Braybrooke, Rebecca, Saini, Gauri, Maher, Toby M, Molyneaux, Philip L, Saunders, Peter, Zhang, Yingze, Gibson, Kevin F, Kass, Daniel J, Rojas, Mauricio, Sembrat, John, Wolters, Paul J, Collard, Harold R, Sundy, John S, O’Riordan, Thomas, Strek, Mary E, Noth, Imre, Ma, Shwu-Fan, Porteous, Mary K, Kreider, Maryl E, Patel, Namrata B, Inoue, Yoshikazu, Hirose, Masaki, Arai, Toru, Akagawa, Shinobu, Eickelberg, Oliver, Fernandez, Isis Enlil, Behr, Jürgen, Mogulkoc, Nesrin, Corte, Tamera J, Glaspole, Ian, Tomassetti, Sara, Ravaglia, Claudia, Poletti, Venerino, Crestani, Bruno, Borie, Raphael, Kannengiesser, Caroline, Parfrey, Helen, Fiddler, Christine, Rassl, Doris, Molina-Molina, Maria, Machahua, Carlos, Worboys, Ana Montes, Gudmundsson, Gunnar, Isaksson, Helgi J, Lederer, David J, Podolanczuk, Anna J, Montesi, Sydney B, Bendstrup, Elisabeth, Danchel, Vivi, Selman, Moises, Pardo, Annie, Henry, Michael T, Keane, Michael P, Doran, Peter, Vašáková, Martina, Sterclova, Martina, Ryerson, Christopher J, Wilcox, Pearce G, Okamoto, Tsukasa, Furusawa, Haruhiko, Miyazaki, Yasunari, Laurent, Geoffrey, Baltic, Svetlana, and Prele, Cecilia

Subjects
Human Genome, Autoimmune Disease, Clinical Research, Lung, Genetics, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, ATP-Binding Cassette Transporters, Case-Control Studies, Cellular Senescence, DNA Helicases, Exoribonucleases, Female, GTPase-Activating Proteins, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, High-Throughput Nucleotide Sequencing, Host-Pathogen Interactions, Humans, Idiopathic Pulmonary Fibrosis, Logistic Models, Male, Mucin-5B, Promoter Regions, Genetic, Pulmonary Surfactant-Associated Protein A, Pulmonary Surfactant-Associated Protein C, RNA, Sequence Analysis, DNA, Telomerase, Telomere-Binding Proteins, targeted resequencing, idiopathic pulmonary fibrosis, genetic variants, rare variants, disease risk alleles, Medical and Health Sciences, Respiratory System
Abstract

Rationale: Several common and rare genetic variants have been associated with idiopathic pulmonary fibrosis, a progressive fibrotic condition that is localized to the lung. Objectives: To develop an integrated understanding of the rare and common variants located in multiple loci that have been reported to contribute to the risk of disease. Methods: We performed deep targeted resequencing (3.69 Mb of DNA) in cases (n = 3,624) and control subjects (n = 4,442) across genes and regions previously associated with disease. We tested for associations between disease and 1) individual common variants via logistic regression and 2) groups of rare variants via sequence kernel association tests. Measurements and Main Results: Statistically significant common variant association signals occurred in all 10 of the regions chosen based on genome-wide association studies. The strongest risk variant is the MUC5B promoter variant rs35705950, with an odds ratio of 5.45 (95% confidence interval, 4.91-6.06) for one copy of the risk allele and 18.68 (95% confidence interval, 13.34-26.17) for two copies of the risk allele (P = 9.60 × 10-295). In addition to identifying for the first time that rare variation in FAM13A is associated with disease, we confirmed the role of rare variation in the TERT and RTEL1 gene regions in the risk of IPF, and found that the FAM13A and TERT regions have independent common and rare variant signals. Conclusions: A limited number of common and rare variants contribute to the risk of idiopathic pulmonary fibrosis in each of the resequencing regions, and these genetic variants focus on biological mechanisms of host defense and cell senescence.

Published
2019

6. Cone-Beam Computed Tomography Improves Location of Transbronchial Cryobiopsy in Interstitial Lung Disease with Limited Extent.

Author

Ravaglia, Claudia, Vignigni, Giovanna, Vizzuso, Antonio, Dubini, Alessandra, Petrella, Enrico, Giampalma, Emanuela, Maitan, Stefano, De Grauw, Arianna Johanna, Piciucchi, Sara, and Poletti, Venerino

Subjects
*BIOPSY, *COMPUTED tomography, *INTERSTITIAL lung diseases, *RESPIRATORY disease diagnosis, *DESCRIPTIVE statistics, *PNEUMOTHORAX, *LONGITUDINAL method, *ADVERSE health care events, *HISTOLOGY, *SENSITIVITY & specificity (Statistics)
Abstract

Introduction: Transbronchial lung cryobiopsy has been recommended as an acceptable alternative to surgical approach for making a histopathological diagnosis in patients with interstitial lung disease (ILD) of undetermined type. In limited diseases (especially if distributed along the subpleural region), sampling the specific area in which the pathological process is more represented could be challenging. Aim of the study was to determine the potential benefit of utilizing cone-beam computed tomography-guided cryobiopsy in patients with limited extent of ILD on CT scan and determine the single impact of each sequential biopsy progressively increasing the total number of biopsies. Methods: This study is a prospective analysis of patients with undetermined ILD and CT scan extent <15% undergoing cone-beam CT-guided cryobiopsy. Each biopsy sample was collected and processed individually and pathologic interpretations were performed sequentially with the pathologist reformulating a new report with the addition of each sample (cumulative yield). Results: Thirty six patients were enrolled. Pathological diagnostic yield was >90%, with almost 80% of diagnostic samples being the first one; when a second biopsy was performed, mean diagnostic yield increased with only a moderately significant difference. No severe adverse events were observed; pneumothorax was documented in 27.8% of the cases. Conclusion: Sequential individual collection and pathologic interpretation of each biopsy sample has confirmed the possibility of obtaining a diagnostic specimen at the first pass if transbronchial cryobiopsy is performed under cone-beam CT. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Detection and Early Referral of Patients With Interstitial Lung Abnormalities: An Expert Survey Initiative

Author

Abtin, Fereidoun, Antoniou, Katerina, Blackwell, Timothy, Brown, Kevin, Chung, Jonathan, Corte, Tamera, Crestani, Bruno, Crossno, Peter, Culver, Daniel, de Andrade, Joao, Deveraj, Anand, Flaherty, Kevin, Gudmundsson, Gunnar, Hatabu, Hiroto, Jacob, Joe, Johansson, Kerri, Kanne, Jeff, Kazerooni, Ella, Kolb, Martin, Lynch, David, Maher, Toby, Martinez, Fernando, Morais, Antonio, Nathan, Steven D., Noth, Imre, Oldham, Justin, Podolanczuk, Anna, Poletti, Venerino, Ravaglia, Claudia, Renzoni, Elizabetta, Richeldi, Luca, Rubin, Geoffrey, Ryerson, Chris, Sahoo, Debasis, Tomassetti, Sara, Spagnolo, Paolo, Strek, Mary E., Suh, Rob, Sverzellati, Nicola, Valeyre, Dominique, Walsh, Simon, Washko, George, White, Eric S., Hunninghake, Gary M., Goldin, Jonathan G., Kadoch, Michael A., Kropski, Jonathan A., Rosas, Ivan O., Wells, Athol U., Yadav, Ruchi, Lazarus, Howard M., Abtin, Fereidoun G., Corte, Tamera J., de Andrade, Joao A., Johannson, Kerri A., Kolb, Martin R., Lynch, David A., Oldham, Justin M., and Washko, George R.

Published
2022
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9. Health-related quality of life profiles, trajectories, persistent symptoms and pulmonary function one year after ICU discharge in invasively ventilated COVID-19 patients, a prospective follow-up study

Author

Tartaglione, Marco, Chiarini, Valentina, Buldini, Virginia, Coniglio, Carlo, Moro, Federico, Orlando, Silvia, Fecarotti, Daniele, Cilloni, Nicola, Giuntoli, Lorenzo, Bellocchio, Angela, Matteo, Emanuele, Pizzilli, Giacinto, Siniscalchi, Antonio, Tartivita, Chiara, Cavalli, Irene, Castelli, Andrea, Marchio, Annalisa, Bacchilega, Igor, Bernabé, Laura, Facondini, Francesca, Morini, Luca, Bissoni, Luca, Viola, Lorenzo, Meconi, Tommaso, Pavoni, Vittorio, Venni, Angelica, Pagni, Aline, Cleta, Patrizia Pompa, Cavagnino, Marco, Guzzo, Alessia, Malfatto, Anna, Adduci, Angelina, Pareschi, Silvia, Bertellini, Elisabetta, Maccieri, Jessica, Marinangeli, Elisa, Racca, Fabrizio, Verri, Marco, Falò, Giulia, Marangoni, Elisabetta, Ottaviani, Irene, Boni, Francesco, Felloni, Giulia, Baccarini, Federico Domenico, Terzitta, Marina, Maitan, Stefano, Tutino, Lorenzo, Senzi, Angelo, Consales, Guglielmo, Becherucci, Filippo, Imbriani, Michele, Orlandi, Paolo, Candini, Silvia, Golfieri, Rita, Ciccarese, Federica, Poerio, Antonio, Muratore, Francesco, Ferrari, Fabio, Mughetti, Martina, Giampalma, Emanuela, Franchini, Loredana, Neziri, Ersenad, Miceli, Marco, Minguzzi, Maria Teresa, Mellini, Lorenzo, Piciucchi, Sara, Monari, Matteo, Valli, Michele, Daniele, Federico, Ferioli, Martina, Nava, Stefano, Lazzari Agli, Luigi Arcangelo, Valentini, Ilaria, Bernardi, Eva, Balbi, Bruno, Contoli, Marco, Padovani, Marianna, Oldani, Stefano, Ravaglia, Claudia, Goti, Patrizio, Gamberini, Lorenzo, Mazzoli, Carlo Alberto, Prediletto, Irene, Sintonen, Harri, Scaramuzzo, Gaetano, Allegri, Davide, Colombo, Davide, Tonetti, Tommaso, Zani, Gianluca, Capozzi, Chiara, Dalpiaz, Giorgia, Agnoletti, Vanni, Cappellini, Iacopo, Melegari, Gabriele, Damiani, Federica, Fusari, Maurizio, Gordini, Giovanni, Laici, Cristiana, Lanza, Maria Concetta, Leo, Mirco, Marudi, Andrea, Papa, Raffaella, Potalivo, Antonella, Montomoli, Jonathan, Taddei, Stefania, Mazzolini, Massimiliano, Ferravante, Anna Filomena, Nicali, Roberta, Ranieri, Vito Marco, Russo, Emanuele, Volta, Carlo Alberto, and Spadaro, Savino

Published
2021
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16. Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study

Author

Castelnuovo, Augusto Di, Costanzo, Simona, Antinori, Andrea, Berselli, Nausicaa, Blandi, Lorenzo, Bruno, Raffaele, Cauda, Roberto, Guaraldi, Giovanni, Menicanti, Lorenzo, My, Ilaria, Parruti, Giustino, Patti, Giuseppe, Perlini, Stefano, Santilli, Francesca, Signorelli, Carlo, Spinoni, Enrico, Stefanini, Giulio G., Vergori, Alessandra, Ageno, Walter, Agodi, Antonella, Aiello, Luca, Agostoni, Piergiuseppe, Moghazi, Samir Al, Astuto, Marinella, Aucella, Filippo, Barbieri, Greta, Bartoloni, Alessandro, Bonaccio, Marialaura, Bonfanti, Paolo, Cacciatore, Francesco, Caiano, Lucia, Cannata, Francesco, Carrozzi, Laura, Cascio, Antonio, Ciccullo, Arturo, Cingolani, Antonella, Cipollone, Francesco, Colomba, Claudia, Crosta, Francesca, Pra, Chiara Dal, Danzi, Gian Battista, D'Ardes, Damiano, Donati, Katleen de Gaetano, Giacomo, Paola Del, Gennaro, Francesco Di, Di Tano, Giuseppe, D'Offizi, Giampiero, Filippini, Tommaso, Fusco, Francesco Maria, Gentile, Ivan, Gialluisi, Alessandro, Gini, Giancarlo, Grandone, Elvira, Grisafi, Leonardo, Guarnieri, Gabriella, Lamonica, Silvia, Landi, Francesco, Leone, Armando, Maccagni, Gloria, Maccarella, Sandro, Madaro, Andrea, Mapelli, Massimo, Maragna, Riccardo, Marra, Lorenzo, Maresca, Giulio, Marotta, Claudia, Mastroianni, Franco, Mazzitelli, Maria, Mengozzi, Alessandro, Menichetti, Francesco, Meschiari, Marianna, Minutolo, Filippo, Montineri, Arturo, Mussinelli, Roberta, Mussini, Cristina, Musso, Maria, Odone, Anna, Olivieri, Marco, Pasi, Emanuela, Petri, Francesco, Pinchera, Biagio, Pivato, Carlo A., Poletti, Venerino, Ravaglia, Claudia, Rinaldi, Massimo, Rognoni, Andrea, Rossato, Marco, Rossi, Ilaria, Rossi, Marianna, Sabena, Anna, Salinaro, Francesco, Sangiovanni, Vincenzo, Sanrocco, Carlo, Scorzolini, Laura, Sgariglia, Raffaella, Simeone, Paola Giustina, Spinicci, Michele, Trecarichi, Enrico Maria, Venezia, Amedeo, Veronesi, Giovanni, Vettor, Roberto, Vianello, Andrea, Vinceti, Marco, Vocciante, Laura, De Caterina, Raffaele, and Iacoviello, Licia

Published
2020
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17. RAAS inhibitors are not associated with mortality in COVID-19 patients: Findings from an observational multicenter study in Italy and a meta-analysis of 19 studies

Author

Di Castelnuovo, Augusto, Costanzo, Simona, Antinori, Andrea, Berselli, Nausicaa, Blandi, Lorenzo, Bonaccio, Marialaura, Cauda, Roberto, Gialluisi, Alessandro, Guaraldi, Giovanni, Menicanti, Lorenzo, Mennuni, Marco, Mussinelli, Roberta, My, Ilaria, Parruti, Giustino, Patti, Giuseppe, Perlini, Stefano, Santilli, Francesca, Signorelli, Carlo, Stefanini, Giulio G., Vergori, Alessandra, Abete, Pasquale, Ageno, Walter, Agostoni, Piergiuseppe, Aiello, Luca, Al Moghazi, Samir, Arboretti, Rosa, Aucella, Filippo, Barbieri, Greta, Barchitta, Martina, Bartoloni, Alessandro, Bonfanti, Paolo, Cacciatore, Francesco, Caiano, Lucia, Carrozzi, Laura, Cascio, Antonio, Castiglione, Giacomo, Cianfrone, Stefania, Ciccullo, Arturo, Cingolani, Antonella, Cipollone, Francesco, Colomba, Claudia, Colombo, Crizia, Cozzi, Ottavia, Crisetti, Annalisa, Crosta, Francesca, Danzi, Gian Battista, D'Ardes, Damiano, de Gaetano Donati, Katleen, Di Gennaro, Francesco, Di Tano, Giuseppe, D'Offizi, Gianpiero, Fusco, Francesco Maria, Gentile, Ivan, Graziani, Emauele, Guarnieri, Gabriella, Larizza, Giovanni, Leone, Armando, Lio, Veronica, Lucia, Mothanje Barbara, Maccagni, Gloria, Madaro, Ferruccio, Maitan, Stefano, Mancarella, Sandro, Manuele, Rosa, Mapelli, Massimo, Maragna, Riccardo, Marcucci, Rossella, Maresca, Giulio, Marongiu, Silvia, Marotta, Claudia, Marra, Lorenzo, Mastroianni, Franco, Mazzitelli, Maria, Mengozzi, Alessandro, Menichetti, Francesco, Meschiari, Marianna, Milic, Jovana, Minutolo, Filippo, Molena, Beatrice, Mussini, Cristina, Musso, Maria, Odone, Anna, Olivieri, Marco, Palimodde, Antonella, Pasi, Emanuela, Pesavento, Raffaele, Petri, Francesco, Pinchera, Biagio, Pivato, Carlo A., Poletti, Venerino, Ravaglia, Claudia, Rossato, Marco, Rossi, Marianna, Sabena, Anna, Salinaro, Francesco, Sangiovanni, Vincenzo, Sanrocco, Carlo, Scoppettuolo, Giancarlo, Scorzolini, Laura, Sgariglia, Raffaella, Simeone, Paola Giustina, Trecarichi, Enrico Maria, Vettor, Roberto, Vianello, Andrea, Vinceti, Marco, Virano, Alexandra, Vocciante, Laura, De Caterina, Raffaele, and Iacoviello, Licia

Published
2020
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18. Prognostic value of transbronchial lung cryobiopsy for the multidisciplinary diagnosis of idiopathic pulmonary fibrosis: a retrospective validation study

Author

Tomassetti, Sara, Ravaglia, Claudia, Wells, Athol U, Cavazza, Alberto, Colby, Thomas V, Rossi, Giulio, Ley, Brett, Ryu, Jay H, Puglisi, Silvia, Arcadu, Antonella, Marchi, Martina, Sultani, Fabio, Martinello, Sabrina, Donati, Luca, Gurioli, Carlo, Gurioli, Christian, Tantalocco, Paola, Hetzel, Jurgen, Dubini, Alessandra, Piciucchi, Sara, Klersy, Catherine, Lavorini, Federico, and Poletti, Venerino

Published
2020
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20. Utility of bronchoalveolar lavage for COVID-19: a perspective from the Dragon consortium

Author

Tomassetti, Sara, primary, Ciani, Luca, additional, Luzzi, Valentina, additional, Gori, Leonardo, additional, Trigiani, Marco, additional, Giuntoli, Leonardo, additional, Lavorini, Federico, additional, Poletti, Venerino, additional, Ravaglia, Claudia, additional, Torrego, Alfons, additional, Maldonado, Fabien, additional, Lentz, Robert, additional, Annunziato, Francesco, additional, Maggi, Laura, additional, Rossolini, Gian Maria, additional, Pollini, Simona, additional, Para, Ombretta, additional, Ciurleo, Greta, additional, Casini, Alessandro, additional, Rasero, Laura, additional, Bartoloni, Alessandro, additional, Spinicci, Michele, additional, Munavvar, Mohammed, additional, Gasparini, Stefano, additional, Comin, Camilla, additional, Cerinic, Marco Matucci, additional, Peired, Anna, additional, Henket, Monique, additional, Ernst, Benoit, additional, Louis, Renaud, additional, Corhay, Jean-louis, additional, Nardi, Cosimo, additional, and Guiot, Julien, additional

Published
2024
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28. Transbronchial lung cryobiopsy under real‐time radial EBUS: First report on a novel twist of the classical technique.

Author

Anagnostopoulos, Nektarios, Petrarulo, Simone, Ravaglia, Claudia, Dubini, Alessandra, Piciucchi, Sara, Stratakos, Grigoris, and Poletti, Venerino

Subjects
LUNGS, LENGTH of stay in hospitals, COUGH
Abstract

Transbronchial lung cryobiopsy (TBLC) is a relatively new technique for obtaining lung biopsies, known for being the least invasive method while offering a high diagnostic yield, a favourable safety profile, and a significant reduction in morbidity, mortality, and hospital stay length compared to surgical lung biopsy. Radial‐EBUS (r‐EBUS) represent a cornerstone modality for accessing 'invisible' peripheral pulmonary lesions. However, a major drawback of these techniques is the lack of 'real‐time' visualization of the biopsy being obtained. In this case report, we present a young woman who was referred to us with a cough, haemoptysis, and a non‐resolving lung consolidation. She underwent TBLC under real‐time rEBUS guidance. This clinical case demonstrates that, in specific clinical scenarios, TBLC with real‐time rEBUS is an excellent diagnostic tool. [ABSTRACT FROM AUTHOR]

Published
2024
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32. A complicated case of whole-lung lavage: a case report

Author

Petrarulo, Simone, primary, Lucchin, Manuel, additional, Oldani, Stefano, additional, Dubini, Alessandra, additional, Piciucchi, Sara, additional, Gori, Alberto, additional, Aiello, Luca, additional, Maitan, Stefano, additional, Spagnolo, Paolo, additional, Ravaglia, Claudia, additional, and Poletti, Venerino, additional

Published
2023
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33. Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?

Author

Albera, Carlo, Antoniou, Katerina M., Altinisik, Goksel, Bendstrup, Elisabeth, Bondue, Benjamin, Borie, Raphael, Brown, Kevin K., Camus, Philippe, Castillo, Diego, Collard, Harold R., Cottin, Vincent, Crimi, Nunzio, Ferrara, Giovanni, Fischer, Aryeh, Gauldie, Jack, Geiser, Thomas, Guenther, Andreas, Hambly, Nathan, Hansell, David M., Harari, Sergio, Jones, Mark G., Keane, Michael, Ley, Brett, Maher, Toby M., Molina-Molina, Maria, Palmucci, Stefano, Poletti, Venerino, Prasse, Antje, Rottoli, Paola, Spagnolo, Paolo, Sterclova, Martina, Torrisi, Sebastiano, Tsitoura, Eliza, Vasakova, Martina, Walsh, Simon L., Wijsenbeek, Marlies S., Wuyts, Wim A., Johannson, Kerri A, Strâmbu, Irina, Ravaglia, Claudia, Grutters, Jan C, Valenzuela, Claudia, Mogulkoc, Nesrin, Luppi, Fabrizio, Richeldi, Luca, Wells, Athol U, Vancheri, Carlo, and Kreuter, Michael

Published
2017
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34. Blockage of interleukin-1β with canakinumab in patients with Covid-19

Author

Landi, Lorenza, Ravaglia, Claudia, Russo, Emanuele, Cataleta, Pierluigi, Fusari, Maurizio, Boschi, Andrea, Giannarelli, Diana, Facondini, Francesca, Valentini, Ilaria, Panzini, Ilaria, Lazzari-Agli, Luigi, Bassi, Paolo, Marchionni, Elisa, Romagnoli, Rossella, De Giovanni, Raffaella, Assirelli, Marina, Baldazzi, Federica, Pieraccini, Fabio, Rametta, Giovanna, Rossi, Lucia, Santini, Luca, Valenti, Ivana, and Cappuzzo, Federico

Published
2020
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36. Association Between Severity of COVID-19 Respiratory Disease and Risk of Obstructive Sleep Apnea.

Author

Iannella, Giannicola, Vicini, Claudio, Lechien, Jerome R., Ravaglia, Claudia, Poletti, Venerino, di Cesare, Simona, Amicarelli, Elena, Gardelli, Lucia, Grosso, Carmela, Patacca, Aria, Magistrelli, Eleonora, De Benedetto, Michele, Toraldo, Domenico Maurizio, Arigliani, Michele, Cammaroto, Giovanni, Meccariello, Giuseppe, De Vito, Andrea, Magliulo, Giuseppe, Greco, Antonio, and de Vincentiis, Marco

Subjects
COVID-19, SCIENTIFIC observation, RETROSPECTIVE studies, ACQUISITION of data, SEVERITY of illness index, RISK assessment, COMPARATIVE studies, SLEEP apnea syndromes, MEDICAL records, QUESTIONNAIRES, OXYGEN therapy, DESCRIPTIVE statistics, DISEASE risk factors
Abstract

Objectives: The purpose of this observational retrospective study was to evaluate, in patients with a severe acute respiratory syndrome coronavirus 2 infection, the association between the severity of coronavirus disease 2019 (COVID-19) respiratory illness and the risk of infected patients to develop obstructive sleep apnea (OSA). Methods: Ninety-six patients with confirmed COVID-19 infection were enrolled in the study. The STOP-BANG questionnaire to investigate the risk of the OSA syndrome was filled in by the patients at admission. The enrolled patients were divided into 2 groups according to the respiratory disease: group 1 (72 patients), hospitalized patients undergoing conventional oxygen therapy; group 2 (24 patients), patients requiring enhanced respiratory support. STOP-BANG results of these 2 groups were compared to observe whether patients with high OSA risk more frequently presented a severe form of COVID-19. Results: 41.6% of the patients in group 2 had a STOP-BANG score between 5 and 8 (high risk of having apnea); in contrast, 20.8% of the patients in group 1 had a STOP-BANG score between 5 and 8, with a statistically significant difference between the 2 groups (P =.05). A complementary trend was observed regarding the proportion of patients in the range 0 to 2, which classifies patients at a low risk of OSA (48.6% vs 20.8% for groups 1 and 2, P =.01). Conclusions: According to our data, the chances of having a severe case of COVID-19 should be considered in patients at high risk of OSA. Current Knowledge/Study Rationale: Emerging research suggests that OSA could represent a potentially important risk factor for the severe forms of COVID-19. The purpose of this observational retrospective study was to evaluate the potential association between OSA and the severity of COVID-19 disease. Study Impact: According to our data, the likelihood of contracting a severe form of COVID-19 disease should be considered in patients at high risk of OSA. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Endobronchial ultrasound‐guided cryobiopsy for diagnosing a case of granulomatosis with polyangiitis.

Author

Calari, Teresa, Petrarulo, Simone, Dubini, Alessandra, Piciucchi, Sara, Ravaglia, Claudia, and Poletti, Venerino

Subjects
DIAGNOSIS, ON-site evaluation, LUNG cancer, TUMOR classification, LUNGS
Abstract

EBUS‐TBNA has represented a revolution in the diagnosis of intrathoracic pathologies, particularly in lung cancer staging, replacing more invasive methods such as mediastinoscopy. However, its role in diagnosing rare benign or malignant mediastinal disorders is still a matter of debate. Over the past few years, the role of EBUS‐guided cryobiopsy has been increasingly emerging as an innovative and minimally invasive technique in diagnosing these disorders, with an excellent safety profile. In this case report, we present the case of a young man brought to our attention after already undergoing a non‐diagnostic trans thoracic needle aspiration (TTNA) procedure for lung consolidations. In our department, he underwent an initial EBUS‐TBNA procedure with inconclusive rapid on‐site evaluation (ROSE), leading to the decision to perform an EBUS‐guided cryobiopsy, which yielded a diagnosis of granulomatosis with polyangiitis without complications. This clinical case demonstrates that in specific contexts, EBUS‐cryobiopsy represents an excellent diagnostic tool. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Clinical implications of interstitial pneumonia with autoimmune features diagnostic criteria in idiopathic pulmonary fibrosis: A case control study

Author

Tomassetti, Sara, primary, Ravaglia, Claudia, additional, Puglisi, Silvia, additional, Wells, Athol U., additional, Ryu, Jay H., additional, Bosi, Marcello, additional, Dubini, Alessandra, additional, Piciucchi, Sara, additional, Girelli, Francesco, additional, Parronchi, Paola, additional, Lavorini, Federico, additional, Rosi, Elisabetta, additional, Luzzi, Valentina, additional, Cerinic, Marco Matucci, additional, and Poletti, Venerino, additional

Published
2023
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48. Progressive pulmonary fibrosis: an expert group consensus statement

Author

Rajan, Sujeet K., primary, Cottin, Vincent, additional, Dhar, Raja, additional, Danoff, Sonye, additional, Flaherty, Kevin R., additional, Brown, Kevin K., additional, Mohan, Anant, additional, Renzoni, Elizabeth, additional, Mohan, Murali, additional, Udwadia, Zarir, additional, Shenoy, Padmanabha, additional, Currow, David, additional, Devraj, Anand, additional, Jankharia, Bhavin, additional, Kulshrestha, Ritu, additional, Jones, Steve, additional, Ravaglia, Claudia, additional, Quadrelli, Silvia, additional, Iyer, Rajam, additional, Dhooria, Sahajal, additional, Kolb, Martin, additional, and Wells, Athol U, additional

Published
2022
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49. Medical Thoracoscopy and Intrapleural Fibrinolytic Therapy for the Management of Pleural Empyema: A Cohort Study

Author

Ravaglia, Claudia, primary, Ghirotti, Corrado, additional, Puglisi, Silvia, additional, Piciucchi, Sara, additional, Gurioli, Carlo, additional, Fabbri, Elisabetta, additional, Sultani, Fabio, additional, Martinello, Sabrina, additional, Corso, Ruggero Massimo, additional, Maitan, Stefano, additional, Sambri, Vittorio, additional, Stella, Franco, additional, and Poletti, Venerino, additional

Published
2022
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50. Phenotypes of Post-COVID-19 Interstitial Lung Disease: Clinical, Radiological, and Pathological Correlations

Author

Gori, Leonardo, primary, Ravaglia, Claudia, additional, Luzzi, Valentina, additional, Ciani, Luca, additional, Biadene, Giulia, additional, Bambina, Sonia, additional, Marinato, Martina, additional, Dubini, Alessandra, additional, Cozzi, Diletta, additional, Cavigli, Edoardo, additional, Comin, Camilla, additional, Pasini, Valeria, additional, Puglisi, Silvia, additional, Cavazza, Alberto, additional, Poletti, Venerino, additional, Spinicc, Michele, additional, Bartoloni, Alessandro, additional, Peired, Anna, additional, Ferraro, Stefania, additional, Papa, Giulia Caterina, additional, Berillo, Edoardo, additional, Nardi, Cosimo, additional, Rosi, Elisabetta, additional, Lavorini, Federico, additional, and Tomassett, Sara, additional

Published
2022
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