33 results on '"Ratomaharo J"'
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2. Approche phénotypique de l’asthme à Madagascar
- Author
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Ratomaharo, J., primary, Randrianasolo, R., additional, Rafanomezantsoa, T.A., additional, Rakotonirina, M.S., additional, Randriantahiry, M., additional, Randriananja, V., additional, Randria, M., additional, and Andriamihaja, R., additional
- Published
- 2023
- Full Text
- View/download PDF
3. Première évaluation médicale du post-COVID-19 à Madagascar
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Ratomaharo, J., primary, Andriananja, V., additional, Randriamahenintsoa, R.T., additional, Andriamamonjisoa, A.J.N., additional, Raberahona, M., additional, Rakotoarivelo, R., additional, Andriamihaja, R., additional, and Randria, M.J., additional
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- 2023
- Full Text
- View/download PDF
4. Résultats préliminaires des troubles fonctionnels respiratoires chez les patients malgaches atteints de la Covid-19
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Ratomaharo, J., primary, Randriantahiry, M., additional, Randrianasolo, R., additional, Rahaingoalidera, T., additional, Rasoafaranirina, O., additional, Andriamihaja, R., additional, Randria, M., additional, and Rakotarvelo, R., additional
- Published
- 2022
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5. Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs
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Bousquet, J., Schünemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J. L., Canonica, G. W., Casale, T. B., Cruz, A. A., Fokkens, W. J., Fonseca, J. A., van Wijk, Gerth R., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P., Lockey, R. F., Lodrup Carlsen, K. C., Mullol, J., Naclerio, R., OʼHehir, R. E., Ohta, K., Palkonen, S., Papadopoulos, N. G., Passalacqua, G., Pawankar, R., Price, D., Ryan, D., Simons, F. E.R., Togias, A., Williams, D., Yorgancioglu, A., Yusuf, O. M., Aberer, W., Adachi, M., Agache, I., Aït-Khaled, N., Akdis, C. A., Andrianarisoa, A., Annesi-Maesano, I., Ansotegui, I. J., Baiardini, I., Bateman, E. D., Bedbrook, A., Beghé, B., Beji, M., Bel, E. H., Ben Kheder, A., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Bieber, T., Bindslev Jensen, C., Blaiss, M. S., Boner, A. L., Bouchard, J., Braido, F., Brightling, C. E., Bush, A., Caballero, F., Calderon, M. A., Calvo, M. A., Camargos, P. A.M., Caraballo, L. R., Carlsen, K. H., Carr, W., Cepeda, A. M., Cesario, A., Chavannes, N. H., Chen, Y. Z., Chiriac, A. M., Chivato Pérez, T., Chkhartishvili, E., Ciprandi, G., Costa, D. J., Cox, L., Custovic, A., Dahl, R., Darsow, U., De Blay, F., Deleanu, D., Denburg, J. A., Devillier, P., Didi, T., Dokic, D., Dolen, W. K., Douagui, H., Dubakiene, R., Durham, S. R., Dykewicz, M. S., El-Gamal, Y., El-Meziane, A., Emuzyte, R., Fiocchi, A., Fletcher, M., Fukuda, T., Gamkrelidze, A., Gereda, J. E., González Diaz, S., Gotua, M., Guzmán, M. A., Hellings, P. W., Hellquist-Dahl, B., Horak, F., Hourihane, Oʼ B.J., Howarth, P., Humbert, M., Ivancevich, J. C., Jackson, C., Just, J., Kalayci, O., Kaliner, M. A., Kalyoncu, A. F., Keil, T., Keith, P. K., Khayat, G., Kim, Y. Y., Koffi NʼGoran, B., Koppelman, G. H., Kowalski, M. L., Kull, I., Kvedariene, V., Larenas-Linnemann, D., Le, L. T., Lemière, C., Li, J., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, M. R., Maurer, M., Mavale-Manuel, S., Mazon, A., Melen, E., Meltzer, E. O., Mendez, N. H., Merk, H., Mihaltan, F., Mohammad, Y., Morais-Almeida, M., Muraro, A., Nafti, S., Namazova-Baranova, L., Nekam, K., Neou, A., Niggemann, B., Nizankowska-Mogilnicka, E., Nyembue, T. D., Okamoto, Y., Okubo, K., Orru, M. P., Ouedraogo, S., Ozdemir, C., Panzner, P., Pali-Schöll, I., Park, H. S., Pigearias, B., Pohl, W., Popov, T. A., Postma, D. S., Potter, P., Rabe, K. F., Ratomaharo, J., Reitamo, S., Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado-Pinto, J., Rosenwasser, L., Rottem, M., Sanchez-Borges, M., Scadding, G. K., Schmid-Grendelmeier, P., Sheikh, A., Sisul, J. C., Solé, D., Sooronbaev, T., Spicak, V., Spranger, O., Stein, R. T., Stoloff, S. W., Sunyer, J., Szczeklik, A., Todo-Bom, A., Toskala, E., Tremblay, Y., Valenta, R., Valero, A. L., Valeyre, D., Valiulis, A., Valovirta, E., Van Cauwenberge, P., Vandenplas, O., van Weel, C., Vichyanond, P., Viegi, G., Wang, D. Y., Wickman, M., Wöhrl, S., Wright, J., Yawn, B. P., Yiallouros, P. K., Zar, H. J., Zernotti, M. E., Zhong, N., Zidarn, M., and Zuberbier, T.
- Published
- 2012
- Full Text
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6. L’épidémie de peste pulmonaire de 2017 à Madagascar
- Author
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Ratomaharo, J., primary, Andriamihaja, R., additional, Razafindrakoto, L., additional, Randriantahiry, M., additional, Andriananja, V., additional, Randria, M., additional, and Rakotoarivelo, R., additional
- Published
- 2020
- Full Text
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7. Environmental Risk Factors in Malagasy Patients Suffering from Chronic Obstructive Pulmonary Disease
- Author
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Ratomaharo, J., primary, Randriantahiry, M., additional, Rakotonanahary, D., additional, Rakotoarivelo, R., additional, Randria, M., additional, and Razafindrakoto, L., additional
- Published
- 2019
- Full Text
- View/download PDF
8. The 2017 Epidemic Pulmonary Plague in Madagascar
- Author
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Ratomaharo, J., primary, Andriamihaja, R., additional, Razafindrakoto, L., additional, Rakotoarivelo, R., additional, and Randria, M., additional
- Published
- 2019
- Full Text
- View/download PDF
9. Test de lever de chaise de 3 minutes (TLC3M) dans la population malgache saine non fumeuse
- Author
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Ratomaharo, J., primary, Randriantahiry, M., additional, Zafimahozo, J., additional, Ranaivosoa, R., additional, Randrianary, H., additional, Rakotoarivelo, R., additional, Razafindrakoto, L., additional, and Randria, M., additional
- Published
- 2019
- Full Text
- View/download PDF
10. Approche épidémiologique et clinique des patients Malgaches atteints de bronchopneumopathie chronique obstructive (BPCO) utilisant les équations spirométriques de référence malgaches (ESRM)
- Author
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Ratomaharo, J., primary, Rakotonanahary, D., additional, Randriantahiry, M., additional, Randrianary, H., additional, Zafimahozo, J., additional, and Ranaivoson, R., additional
- Published
- 2018
- Full Text
- View/download PDF
11. Équations spirométriques de référence de la population malgache née et vivant en France
- Author
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Ratomaharo, J., primary, Rakotonanahary, D., additional, Ranaivoson, R., additional, and Randriantahiry, M., additional
- Published
- 2017
- Full Text
- View/download PDF
12. Équations spirométriques de référence de la population malgache, National Health and Nutrition Examination Survey (NHANESIII) et Global Lung Function Initiative (GLI12)
- Author
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Ratomaharo, J., primary, Randriantahiry, M., additional, Razafindrakoto, L., additional, and Andriamihaja, R., additional
- Published
- 2016
- Full Text
- View/download PDF
13. Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs
- Author
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Bousquet J, Schünemann HJ, Samolinski B, Demoly P, Baena-Cagnani CE, Bachert C, Bonini S, Boulet LP, Bousquet PJ, Brozek JL, Canonica GW, Casale TB, Cruz AA, Fokkens WJ, Fonseca JA, van Wijk RG, Grouse L, Haahtela T, Khaltaev N, Kuna P, Lockey RF, Lodrup Carlsen KC, Mullol J, Naclerio R, O'Hehir RE, Ohta K, Palkonen S, Papadopoulos NG, Passalacqua G, Pawankar R, Price D, Ryan D, Simons FE, Togias A, Williams D, Yorgancioglu A, Yusuf OM, Aberer W, Adachi M, Agache I, Aït-Khaled N, Akdis CA, Andrianarisoa A, Annesi-Maesano I, Ansotegui IJ, Baiardini I, Bateman ED, Bedbrook A, Beghé B, Beji M, Bel EH, Ben Kheder A, Bennoor KS, Bergmann KC, Berrissoul F, Bieber T, Bindslev Jensen C, Blaiss MS, Boner AL, Bouchard J, Braido F, Brightling CE, Bush A, Caballero F, Calderon MA, Calvo MA, Camargos PA, Caraballo LR, Carlsen KH, Carr W, Cepeda AM, Cesario A, Chavannes NH, Chen YZ, Chiriac AM, Chivato Pérez T, Chkhartishvili E, Ciprandi G, Costa DJ, Cox L, Custovic A, Dahl R, Darsow U, De Blay F, Deleanu D, Denburg JA, Devillier P, Didi T, Dokic D, Dolen WK, Douagui H, Dubakiene R, Durham SR, Dykewicz MS, El-Gamal Y, El-Meziane A, Emuzyte R, Fiocchi A, Fletcher M, Fukuda T, Gamkrelidze A, Gereda JE, González Diaz S, Gotua M, Guzmán MA, Hellings PW, Hellquist-Dahl B, Horak F, Hourihane JO, Howarth P, Humbert M, Ivancevich JC, Jackson C, Just J, Kalayci O, Kaliner MA, Kalyoncu AF, Keil T, Keith PK, Khayat G, Kim YY, Koffi N'goran B, Koppelman GH, Kowalski ML, Kull I, Kvedariene V, Larenas-Linnemann D, Le LT, Lemière C, Li J, Lieberman P, Lipworth B, Mahboub B, Makela MJ, Martin F, Marshall GD, Martinez FD, Masjedi MR, Maurer M, Mavale-Manuel S, Mazon A, Melen E, Meltzer EO, Mendez NH, Merk H, Mihaltan F, Mohammad Y, Morais-Almeida M, Muraro A, Nafti S, Namazova-Baranova L, Nekam K, Neou A, Niggemann B, Nizankowska-Mogilnicka E, Nyembue TD, Okamoto Y, Okubo K, Orru MP, Ouedraogo S, Ozdemir C, Panzner P, Pali-Schöll I, Park HS, Pigearias B, Pohl W, Popov TA, Postma DS, Potter P, Rabe KF, Ratomaharo J, Reitamo S, Ring J, Roberts R, Rogala B, Romano A, Roman Rodriguez M, Rosado-Pinto J, Rosenwasser L, Rottem M, Sanchez-Borges M, Scadding GK, Schmid-Grendelmeier P, Sheikh A, Sisul JC, Solé D, Sooronbaev T, Spicak V, Spranger O, Stein RT, Stoloff SW, Sunyer J, Szczeklik A, Todo-Bom A, Toskala E, Tremblay Y, Valenta R, Valero AL, Valeyre D, Valiulis A, Valovirta E, Van Cauwenberge P, Vandenplas O, van Weel C, Vichyanond P, Viegi G, Wang DY, Wickman M, Wöhrl S, Wright J, Yawn BP, Yiallouros PK, Zar HJ, Zernotti ME, Zhong N, Zidarn M, Zuberbier T, World Health Organization Collaborating Center for Asthma, and Rhinitis.
- Published
- 2012
14. Severe Chronic Allergic (and related) Diseases: a uniform approach- a MeDALL- GA(2)LEN-ARIA Position Paper
- Author
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WHO Collaborating Center for Asthma, Rhinitis, Bousquet, J, Anto, Jm, Demoly, P, Schünemann, Hj, Togias, A, Akdis, M, Auffray, C, Bachert, C, Bieber, T, Bousquet, Pj, Carlsen, Kh, Casale, Tb, Cruz, Aa, Keil, T, Lodrup Carlsen KC, Maurer, M, Ohta, K, Papadopoulos, Ng, Roman Rodriguez, M, Samolinski, B, Agache, I, Andrianarisoa, A, Ang, Cs, Annesi Maesano, I, Ballester, F, Baena Cagnani CE, Basagaña, X, Bateman, Ed, Bel, Eh, Bedbrook, A, Beghe', Bianca, Beji, M, Ben Kheder, A, Benet, M, Bennoor, Ks, Bergmann, Kc, Berrissoul, F, Bindslev Jensen, C, Bleecker, Er, Bonini, S, Boner, Al, Boulet, Lp, Brightling, Ce, Brozek, Jl, Bush, A, Busse, Ww, Camargos, Pa, Canonica, Gw, Carr, W, Cesario, A, Chen, Yz, Chiriac, Am, Costa, Dj, Cox, L, Custovic, A, Dahl, R, Darsow, U, Didi, T, Dolen, Wk, Douagui, H, Dubakiene, R, El Meziane, A, Fonseca, Ja, Fokkens, Wj, Fthenou, E, Gamkrelidze, A, Garcia Aymerich, J, Gerth van Wijk, R, Gimeno Santos, E, Guerra, S, Haahtela, T, Haddad, H, Hellings, Pw, Hellquist Dahl, B, Hohmann, C, Howarth, P, Hourihane, Jo, Humbert, M, Jacquemin, B, Just, J, Kalayci, O, Kaliner, Ma, Kauffmann, F, Kerkhof, M, Khayat, G, Koffi N'Goran, B, Kogevinas, M, Koppelman, Gh, Kowalski, Ml, Kull, I, Kuna, P, Larenas, D, Lavi, I, Le, Lt, Lieberman, P, Lipworth, B, Mahboub, B, Makela, Mj, Martin, F, Martinez, Fd, Marshall, Gd, Mazon, A, Melen, E, Meltzer, Eo, Mihaltan, F, Mohammad, Y, Mohammadi, A, Momas, I, Morais Almeida, M, Mullol, J, Muraro, A, Naclerio, R, Nafti, S, Namazova Baranova, L, Nawijn, Mc, Nyembue, Td, Oddie, S, O'Hehir, Re, Okamoto, Y, Orru, Mp, Ozdemir, C, Ouedraogo, Gs, Palkonen, S, Panzner, P, Passalacqua, G, Pawankar, R, Pigearias, B, Pin, I, Pinart, M, Pison, C, Popov, Ta, Porta, D, Postma, Ds, Price, D, Rabe, Kf, Ratomaharo, J, Reitamo, S, Rezagui, D, Ring, J, Roberts, R, Roca, J, Rogala, B, Romano, A, Rosado Pinto, J, Ryan, D, Sanchez Borges, M, Scadding, Gk, Sheikh, A, Simons, Fe, Siroux, V, Schmid Grendelmeier PD, Smit, Ha, Sooronbaev, T, Stein, Rt, Sterk, Pj, Sunyer, J, Terreehorst, I, Toskala, E, Tremblay, Y, Valenta, R, Valeyre, D, Vandenplas, O, van Weel, C, Vassilaki, M, Varraso, R, Viegi, G, Wang, Dy, Wickman, M, Williams, D, Wöhrl, S, Wright, J, Yorgancioglu, A, Yusuf, Om, Zar, Hj, Zernotti, Me, Zidarn, M, Zhong, N, Zuberbier, T., Beghe', B., Fthenou, E., Boudier, Anne, Hôpital Arnaud de Villeneuve [CHRU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), IMIM-Hospital del Mar, Generalitat de Catalunya, Center for Research in Environmental Epidemiology (CREAL), Universitat Pompeu Fabra [Barcelona] (UPF)-Catalunya ministerio de salud, CIBER Epidemiologia y Salud Publica, CIBER de Epidemiología y Salud Pública (CIBERESP), Universitat Pompeu Fabra [Barcelona] (UPF), WHO Collaborating Center for Asthma and Rhinitis, Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Pharmacoepidemiologie et évaluation de l'impact des produits de santé sur les populations, Université Bordeaux Segalen - Bordeaux 2-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Clinical Epidemiology and Biostatistics and Medicine, McMaster University [Hamilton, Ontario], National Institute of Allergy and Infectious Diseases [Bethesda] (NIAID-NIH), National Institutes of Health [Bethesda] (NIH), Swiss Institute of Allergy and Asthma Research (SIAF), Universität Zürich [Zürich] = University of Zurich (UZH), Génomique fonctionnelle et biologie systémique pour la santé, Institut des Sciences Biologiques du CNRS, Upper Airway Research Laboratory (URL), Ghent University Hospital, Department of Dermatology and Allergy, VU University Medical Center [Amsterdam], Department of Paediatrics, University of Oslo (UiO)-Oslo University Hospital [Oslo], Division of Allergy and Immunology, Department of Medicine, Creighton University, ProAR - FMB, Federal University of Bahia School of Medicine, Epidemiology and Health Economics, Instittute of Social Health-Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Department of Dermatology, Medical School-Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Division of Respiratory Medicine and Allergology, Teikyo University School of Medicine, Allergy Department, 2nd Pediatric Clinic, Son Pisa Primary Care Centre, IB-Salut Balearic Health Service, Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw - Poland-Faculté de Pharmacie de Paris, Department of Allergy and Clinical Immunology, Faculty of Medicine-Transylvania University, Public Hospital Medical Service, Ministry of Health [Mozambique], Epidémiologie des maladies infectieuses et modélisation (ESIM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Center for Public Health Research (CSISP), University of Valencia, Respiratory Medicine, Università degli studi di Genova = University of Genoa (UniGe)-School of Specialization, Faculty of Medicine, Catholic University, Health Sciences Faculty, University of Cape Town, Department of Pulmonology, University of Amsterdam [Amsterdam] (UvA)-Academic Medical Centre, Divisions of Human Genetics Infection, Inflammation and Repair, University of Southampton-School of Medicine, Service de Pneumologie Allergologie, Hôpital La Rabta [Tunis], Service de Pneumologie, Hôpital Abderrahmen Mami, National Asthma Centre, National Institute of Diseases of the Chest and Hospital (NIDCH), Pneumologie / Anesthésie - réanimation / Oxygénothérapie, Hôpital AKS Phnom Penh-Hôpital Provincial de Siemreap, Department of Dermatology and Allergy Center, Odense University Hospital, Center for Genomics and Personalized Medicine, Wake Forest University, Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy and Department of Medicine-University of Naples Federico II = Università degli studi di Napoli Federico II, Università degli studi di Verona = University of Verona (UNIVR), Institut de cardiologie et de pneumologie, Université Laval [Québec] (ULaval)-Centre Hospitalier de Laval (CH Laval), Department of Respiratory Medicine and Thoracic Surgery, University of Leicester-Institute for Lung Health, Department of Paediatric Respiratory Medicine, Imperial College London-Royal Brompton Hospital-National Heart and Lung Institute [UK], Department of Medicine, University of Wisconsin School of Medicine and Public Health, Department of Pediatrics, Universidade Federal de Minas Gerais [Belo Horizonte] (UFMG)-Medical School, Allergy & Respiratory Diseases, Università degli studi di Genova = University of Genoa (UniGe)-Department of Internal Medicine (DIMI), Allergy & Asthma Associates, University of California [Irvine] (UC Irvine), University of California (UC)-University of California (UC), Deputy Scientific Director, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Pisana, Department of Thoracic Surgery, Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma] (Unicatt), National Cooperative Group of Pediatric Research on Asthma, Asthma Clinic and Education Center of the Capital Institute of Pediatrics, Service des Premiers Soins, Université Montpellier 1 (UM1), Osteopathic College of Medicine, Nova Southeastern University (NSU), Respiratory Research Group, University of Manchester [Manchester]-School of Translational Medicine, Department of Respiratory Diseases, Aarhus University Hospital, Department of Dermatology and Allergy Biederstein, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Service de pneumologie, Centre hospitalier de la région d'Annecy, Service de pneumo-allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Allergy Centre, Vilnius University Antakalnis Hospital, Société Marocaine des Maladies Respiratoires, Centre of Respiratory Diseases and Allergy-Centre commercial Nadia, Allergy Division, Hospital S. João-Centre for Research in Health Technologies and Information Systems (CINTESIS)-Biostatistics and Medical Informatics Department-Porto University Medical School, Department of Otorhinolaryngology, Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), University of Amsterdam [Amsterdam] (UvA)-University of Amsterdam [Amsterdam] (UvA), Department of Social Medicine, University of Crete [Heraklion] (UOC)-Faculty of Medicine, Health Care, Minister Of Labour-Ministry of Labor, Health and Social Affairs, Section of Allergology, Erasmus Medical Centre, Epidemiology and Biostatistics Division, University of Arizona-Associate Research Scientist, Respiratory Sciences-Arizona Respiratory Center, Helsinki University Hospital-Skin and Allergy Hospital, Centre Hospitalier de Bigorre [Tarbes]-Association Franco-Libanaise de Pneumologie (AFLP), Department of Otorhinolaryngology, Head, and Neck Surgery, University Hospital Leuven, Engineering and the Environment, University of Southampton, Paediatrics and Child Health, University College Cork (UCC), Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre de l'Asthme et des Allergies [CHU Trousseau], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Pediatric Allergy and Asthma Unit, Ihsan Dogramaci Children's Hospital-Hacettepe University School of Medicine, Institute for Asthma and Allergy, George Washington University Medical School, Department of Epidemiology, University of Groningen [Groningen]-University Medical Center Groningen [Groningen] (UMCG)-Groningen Research Institute for Asthma and COPD (GRIAC), Université Saint-Joseph de Beyrouth (USJ)-Faculté de Médecine-Hôtel-Dieu de France, Service des Maladies Respiratoires, CHU de Cocody-UFR des Sciences Médicales, Pediatric Pulmonology, Allergology & Epidemiology, University of Groningen [Groningen]-University Medical Center Groningen [Groningen] (UMCG)-Beatrix Children's Hospital-Groningen Research Institute for Asthma and COPD, Department of Clinical Immunology and Allergy, Medical University of Łódź (MUL)-Faculty ot Medicine, Centre for Allergy Research, Karolinska Institutet [Stockholm], Department of Clinical Science and Education, Division of Internal Medicine, Asthma and Allergy, Medical University of Łódź (MUL)-Barlicki University Hospital, Hospital Medica Sur, Physiology Department, University of Medicine and Pharmacy, Division of Allergy Immunology, Department of Medicine-The University of Tennessee Health Science Center [Memphis] (UTHSC), university of dundee asthma - allergic rhinitis - COPD - beta-2-adrenoceptor, University of Dundee, Pulmonary and allergy unit, American University of Sharjah-Rashid Hospital-Dubai Health Authority (DHA), Association Franco-Vietnamienne de Pneumologie (AFVP), Centre Hospitalier de Compiègne (CHC), Arizona Respiratory Center, Department of Medicine, Clinical Immunology and Allergy, University of Mississippi Medical Center (UMMC), Institute of Environmental Medicine, Karolinska Institutet [Stockholm]-Karolinska University Hospital [Stockholm]-Astrid Lindgren Children's Hospital, Allergy & Asthma Medical Group & Research Center, University of California [San Diego] (UC San Diego), Pneumology Department, Marius Nasta Institute of Pneumology, Department of Internal Medicine, Tishreen University School of Medicine, Association Franco-Marocaine de Pathologie Thoracique (AFMAPATH), Collège National des Pneumologues Marocains, Epidémiologie Environnementale : Impact Sanitaire des Pollutions (EA 4064), Université Paris Descartes - Paris 5 (UPD5), Immunoallergy Department, Hospital CUF Descobertas, Rhinology Unit & Smell Clinic, Universitat de Barcelona (UB)-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)-Department of Medicine-Hospital Clinic-ENT Department, Allergy Unit, Università degli Studi di Padova = University of Padua (Unipd)-Department of Paediatrics, Section of Otolaryngology-Head & Neck Surgery (OHNS), University of Chicago, Clinique des maladies respiratoires, centre hospitalo-universitaire Mustapha Pacha d'Alger (CHUMA), Scientific Center for Children's Health, Russian Academy of Medical Sciences (RAMS), Laboratory of Allergology and Pulmonary Diseases, University of Groningen [Groningen]-University Medical Center Groningen [Groningen] (UMCG)-Department of Pathology and Medical Biology-GRIAC Research Institute, ENT Department, University of Kinshasa (UNIKIN), Bradford Neonatology, Bradford Teaching Hospitals NHS Foundation Trust-Bradford Institute for Health Research, Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital-Monash University Building, AMREP, Chiba University Hospital, Asthme Rhinite allergique, Pharmacie, Division of Pediatric Allergy and Immunology, marmara university, Pédiatrie, Centre Hospitalier National Pédiatrique Charles de Gaulle (CHNP-CDG), European Federation of Allergy (EFA), Airways Diseases Patients' Associations, Department of Allergology and Clinical Immunology, Charles University [Prague] (CU)-Medical Faculty in Pilsen, Immunopharmacology, Nippon Medical School-Medical Research Council Clinical, Laboratoire du Sommeil et de l'Effort, Société de Pneumologie de Langue Française (SPLF)-Clinique St George, Institut d'oncologie/développement Albert Bonniot de Grenoble (INSERM U823), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de bioénergétique fondamentale et appliquée (LBFA), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Clinic of Allergy and Asthma, Medical University Sofia-Alexander's University Hospital, Regional Health Service - Lazio, Primary Care Respiratory Medicine, University of Aberdeen-Department of General Practice and Primary Care-General Practice Airways Group (GPIAG), Department of Pulmonary Medicine, Leiden University Medical Center (LUMC), Pneumalgia, Centre Hospitalier Regional-Espace Francophone de Pneumologie (EFP)-Société de Pneumologie de l'Océan Indien (SPOI), Association Franco-Algérienne de Pneumologie (AFAP), Espace Francophone de pneumologie de la SPLF, Department of Pneumology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)-Hospital Clínic de Barcelona-Institut Clínic del Tórax (ICT)-CIBER de Enfermedades Respiratorias (CIBERES)-University of Barcelona, Allergology and Clinical Immunology, Medical University of Silesia (SUM)-Chair and Clinical Department of Internal Diseases, UCSC-Allergy Unit, Complesso Integrato Columbus-Department of Internal Medicine and Geriatrics, Hospital da Luz, Medical Centre, Woodbrook Medical Centre, Research Fellow, University of Aberdeen-Department of General Practice, Centro Médico Docente La Trinidad, Department of Pharmacology, University College of London [London] (UCL)-The Royal National Throat, Nose and Ear Hospital, Primary Care Research & Development, University of Edinburgh-Centre for Population Health Sciences, Section of Allergy & Clinical Immunology, University of Manitoba [Winnipeg]-Department of Pediatrics & Child Health, Allergy Unit - Department of Dermatology, Julius Center for Health Sciences and Primary Care, University Medical Center [Utrecht], National Centre of Cardiology and Internal Medicine, Ministry of Health Kyrgyz Republic, School of Medicine, Pontifícia Universidade Católica, Department of ENT and Pediatrics, Finnish Institute of Occupational Health, Department of Obstetrics and Gynaecology, Université Laval [Québec] (ULaval)-Faculty of Medicine, Christian Doppler Laboratory for Allergy Research, Medizinische Universität Wien = Medical University of Vienna-Division of Immunopathology-Department of Pathophysiology and Allergy Research-Center for Pathophysiology, Infectiology and Immunology, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Avicenne [AP-HP], Department of Chest Medicine, Mont-Godinne Hospital-Catholic University of Louvain de Mont-Godinne, Department of Primary and Community Care, Radboud University Medical Center [Nijmegen], Epidemiology Unit, National Research Council (CNR)-Institute of Biomedicine and Molecular Immunology (IBIM), Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Department of Otolaryngology, National University of Singapore (NUS)-Yong Loo Lin School of Medicine, Karolinska Institutet [Stockholm]-Sachs' Children's Hospital, GLP Analytical Facility, School of Pharmacy, Department of Dermatology Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna (MUW), Celal Bayar University School of Medicine, Allergy and Asthma Clinics, The Allergy and Asthma Institute, Department of Paediatrics and Child Health, Respiratory and Allergic Diseases, University Clinic of Respiratory and Allergic Diseases Golnik, State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Diseases-Guangzhou Medical College, Secretary General of the Global Allergy and Asthma European Network (GA2LEN), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], In collaboration with the WHO Collaborating Center for Asthma and Rhinitis, University of Genoa (UNIGE)-School of Specialization, CNR, Rome, Italy and Department of Medicine-University of Naples Federico II, University of Verona (UNIVR), Medical School-Federal University of Minas Gerais, University of Genoa (UNIGE)-Department of Internal Medicine (DIMI), University of California [Irvine] (UCI), University of California-University of California, Catholic University Rome, University of Amsterdam [Amsterdam] (UvA)-Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), University of Amsterdam [Amsterdam] (UvA), Centre Hospitalier de Bigorre (Tarbes)-Association Franco-Libanaise de Pneumologie (AFLP), CUF-Descobertas Hospital, Universita degli Studi di Padova-Department of Paediatrics, Medical Faculty in Pilsen-Charles University in Prague - the First Faculty of Medicine, Centro Medico-Docente La Trinidad, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]-Instittute of Social Health, Department of Internal Medicine (DIMI)-University of Genoa (UNIGE), Medical University of Silesia-Chair and Clinical Department of Internal Diseases, Dermatology, Internal Medicine, Immunology, Hôpital Arnaud de Villeneuve, Centre Hospitalier Régional Universitaire [Montpellier] ( CHRU Montpellier ), Centre de recherche en épidémiologie et santé des populations ( CESP ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Université Paris-Sud - Paris 11 ( UP11 ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Center for Research in Environmental Epidemiology ( CREAL ), Universitat Pompeu Fabra [Barcelona]-Catalunya ministerio de salud, Universitat Pompeu Fabra [Barcelona], WHO(OMS), Université Bordeaux Segalen - Bordeaux 2-Université de Rouen Normandie ( UNIROUEN ), Normandie Université ( NU ) -Normandie Université ( NU ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), National Institute of Allergy and Infectious Diseases [Bethesda], National Institutes of Health ( NIH ), Swiss Institute of Allergy and Asthma Research ( SIAF ), University of Zürich [Zürich] ( UZH ), Upper Airway Research Laboratory ( URL ), University Medical Center, University of Oslo ( UiO ) -Oslo University Hospital, Charite-Universitatsmedizin Berlin [Berlin]-Instittute of Social Health, Medical School-Charité - University Medicine Berlin, Medical University of Warsaw-Faculté de Pharmacie de Paris, Ministry of Health, Epidémiologie des maladies infectieuses et modélisation ( ESIM ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Center for Public Health Research ( CSISP ), University of Genoa ( UNIGE ) -School of Specialization, University of Amsterdam [Amsterdam] ( UvA ) -Academic Medical Centre, University of Southampton [Southampton]-School of Medicine, Hôpital La Rabta [Tunis), Wake Forest University Health Sciences, CNR, Rome, Italy and Department of Medicine-Second University of Naples, Università degli Studi di Verona, Université Laval-l'Hôpital Laval, Imperial College London-Royal Brompton Hospital-National Heart and Lung Institute, University of Genoa ( UNIGE ) -Department of Internal Medicine (DIMI), Southern California Research, Université Montpellier 1 ( UM1 ), Nova Southeastern University, Technische Universität München [München] ( TUM ), Academic Medical Center [Amsterdam] ( AMC ), University of Amsterdam [Amsterdam] ( UvA ) -University of Amsterdam [Amsterdam] ( UvA ), University of Crete ( UOC ) -Faculty of Medicine, University of Southampton [Southampton], UUniversity College Cork - National University of Ireland, Cork (UCC), Université Paris-Sud - Paris 11 ( UP11 ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Antoine Béclère, Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Trousseau [APHP], University of Groningen [Groningen]-University Medical Center Groningen-Groningen Research Institute for Asthma and COPD (GRIAC), Université Saint-Joseph de Beyrouth ( USJ ) -Faculté de Médecine-Hôtel-Dieu de France, University of Groningen [Groningen]-University Medical Center Groningen-Beatrix Children's Hospital-Groningen Research Institute for Asthma and COPD, Medical University of Łódź ( MUL ) -Faculty ot Medicine, Medical University of Łódź ( MUL ) -Barlicki University Hospital, Department of Medicine-University of Tennessee College for Medicine, Association Franco-Vietnamienne de Pneumologie ( AFVP ), University of Mississippi Medical Center, University of California [San Diego] ( UC San Diego ), Association Franco-Marocaine de Pathologie Thoracique ( AFMAPATH ), Epidémiologie Environnementale : Impact Sanitaire des Pollutions ( EA 4064 ), Université Paris Descartes - Paris 5 ( UPD5 ), Universitat de Barcelona ( UB ) -Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)-Department of Medicine-Hospital Clinic-ENT Department, Section of Otolaryngology-Head & Neck Surgery ( OHNS ), University of Groningen [Groningen]-University Medical Center Groningen-Department of Pathology and Medical Biology-GRIAC Research Institute, University Hospital of Kinshasa, European Federation of Allergy ( EFA ), Institut d'oncologie/développement Albert Bonniot de Grenoble ( INSERM U823 ), Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Bioenergétique fondamentale et appliquée ( LBFA ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Department of General Practice and Primary Care-General Practice Airways Group (GPIAG)-University of Aberdeen, Association Franco-Algérienne de Pneumologie ( AFAP ), Department of General Practice-University of Aberdeen, University College of London [London] ( UCL ) -The Royal National Throat, Nose and Ear Hospital, University Medical Center Utrecht, Faculty of Medicine-Laval University [Québec], Medical University of Vienna-Division of Immunopathology-Department of Pathophysiology and Allergy Research-Center for Pathophysiology, Infectiology and Immunology, Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Avicenne, National University of Singapore ( NUS ) -Yong Loo Lin School of Medicine, Department of Dermatology Division of Immunology, Allergy and Infectious Diseases ( DIAID ), Secretary General of the Global Allergy and Asthma European Network ( GA2LEN ), Network of Excellence, Charité - Universitätsmedizin Berlin, CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK (BIHR), Universiteit Leiden-Universiteit Leiden, and Medizinische Universität Wien = Medical University of Vienna
- Subjects
MESH: Asthma ,severity ,MESH: Comorbidity ,Comorbidity ,Severity of Illness Index ,urticaria ,MESH : Chronic Disease ,MESH: Practice Guidelines as Topic ,MESH : Dermatitis, Atopic ,MESH: Urticaria ,risk ,216-31 [Rhinitis ,atopy ,allergen Int Arch Allergy Immunol. 2012,158(3)] ,atopic dermatitis ,MESH : Rhinitis ,MESH: Rhinitis ,[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie ,Effective primary care and public health [NCEBP 7] ,Immunoglobulin E - Asthma - Rhinitis - Rhinosinusitis - Urticaria - Atopic dermatitis ,MESH : Practice Guidelines as Topic ,Practice Guidelines as Topic ,MESH : Comorbidity ,MESH : Severity of Illness Index ,IgE ,MESH: Sinusitis ,MESH : Urticaria ,MESH: Hypersensitivity ,macromolecular substances ,MESH : Asthma ,Dermatitis, Atopic ,rhinitis ,SDG 3 - Good Health and Well-being ,MESH: Dermatitis, Atopic ,MESH: Severity of Illness Index ,Hypersensitivity ,Humans ,Sinusitis ,rhinosinusitis ,MESH : Hypersensitivity ,MESH: Humans ,MESH: Chronic Disease ,MESH : Humans ,Asthma ,Atopic dermatitis ,Immunoglobulin E ,Rhinitis ,Rhinosinusitis ,Urticaria ,asthma ,allergy ,MESH : Sinusitis ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Chronic Disease ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,control - Abstract
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel
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- 2012
15. Severe chronic allergic (and related) diseases: A uniform approach - A MeDALL - GA2 LEN - ARIA position paper
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Bousquet, J. Anto, J.M. Demoly, P. Schünemann, H.J. Togias, A. Akdis, M. Auffray, C. Bachert, C. Bieber, T. Bousquet, P.J. Carlsen, K.H. Casale, T.B. Cruz, A.A. Keil, T. Lodrup Carlsen, K.C. Maurer, M. Ohta, K. Papadopoulos, N.G. Roman Rodriguez, M. Samolinski, B. Agache, I. Andrianarisoa, A. Ang, C.S. Annesi-Maesano, I. Ballester, F. Baena-Cagnani, C.E. Basagaña, X. Bateman, E.D. Bel, E.H. Bedbrook, A. Beghé, B. Beji, M. Ben Kheder, A. Benet, M. Bennoor, K.S. Bergmann, K.C. Berrissoul, F. Bindslev Jensen, C. Bleecker, E.R. Bonini, S. Boner, A.L. Boulet, L.P. Brightling, C.E. Brozek, J.L. Bush, A. Busse, W.W. Camargos, P.A.M. Canonica, G.W. Carr, W. Cesario, A. Chen, Y.Z. Chiriac, A.M. Costa, D.J. Cox, L. Custovic, A. Dahl, R. Darsow, U. Didi, T. Dolen, W.K. Douagui, H. Dubakiene, R. El-Meziane, A. Fonseca, J.A. Fokkens, W.J. Fthenou, E. Gamkrelidze, A. Garcia-Aymerich, J. Van Wijk, R.G. Gimeno-Santos, E. Guerra, S. Haahtela, T. Haddad, H. Hellings, P.W. Hellquist-Dahl, B. Hohmann, C. Howarth, P. Hourihane, J.O. Humbert, M. Jacquemin, B. Just, J. Kalayci, O. Kaliner, M.A. Kauffmann, F. Kerkhof, M. Khayat, G. Koffi N'Goran, B. Kogevinas, M. Koppelman, G.H. Kowalski, M.L. Kull, I. Kuna, P. Larenas, D. Lavi, I. Le, L.T. Lieberman, P. Lipworth, B. Mahboub, B. Makela, M.J. Martin, F. Martinez, F.D. Marshall, G.D. Mazon, A. Melen, E. Meltzer, E.O. Mihaltan, F. Mohammad, Y. Mohammadi, A. Momas, I. Morais-Almeida, M. Mullol, J. Muraro, A. Naclerio, R. Nafti, S. Namazova-Baranova, L. Nawijn, M.C. Nyembue, T.D. Oddie, S. O'Hehir, R.E. Okamoto, Y. Orru, M.P. Ozdemir, C. Ouedraogo, G.S. Palkonen, S. Panzner, P. Passalacqua, G. Pawankar, R. Pigearias, B. Pin, I. Pinart, M. Pison, C. Popov, T.A. Porta, D. Postma, D.S. Price, D. Rabe, K.F. Ratomaharo, J. Reitamo, S. Rezagui, D. Ring, J. Roberts, R. Roca, J. Rogala, B. Romano, A. Rosado-Pinto, J. Ryan, D. Sanchez-Borges, M. Scadding, G.K. Sheikh, A. Simons, F.E.R. Siroux, V. Schmid-Grendelmeier, P.D. Smit, H.A. Sooronbaev, T. Stein, R.T. Sterk, P.J. Sunyer, J. Terreehorst, I. Toskala, E. Tremblay, Y. Valenta, R. Valeyre, D. Vandenplas, O. Van Weel, C. Vassilaki, M. Varraso, R. Viegi, G. Wang, D.Y. Wickman, M. Williams, D. Wöhrl, S. Wright, J. Yorgancioglu, A. Yusuf, O.M. Zar, H.J. Zernotti, M.E. Zidarn, M. Zhong, N. Zuberbier, T.
- Subjects
macromolecular substances - Abstract
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright © 2012 S. Karger AG, Basel.
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- 2012
16. Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs
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Bousquet, J. Schünemann, H.J. Samolinski, B. Demoly, P. Baena-Cagnani, C.E. Bachert, C. Bonini, S. Boulet, L.P. Bousquet, P.J. Brozek, J.L. Canonica, G.W. Casale, T.B. Cruz, A.A. Fokkens, W.J. Fonseca, J.A. Van Wijk, R.G. Grouse, L. Haahtela, T. Khaltaev, N. Kuna, P. Lockey, R.F. Lodrup Carlsen, K.C. Mullol, J. Naclerio, R. O'hehir, R.E. Ohta, K. Palkonen, S. Papadopoulos, N.G. Passalacqua, G. Pawankar, R. Price, D. Ryan, D. Simons, F.E.R. Togias, A. Williams, D. Yorgancioglu, A. Yusuf, O.M. Aberer, W. Adachi, M. Agache, I. Aït-Khaled, N. Akdis, C.A. Andrianarisoa, A. Annesi-Maesano, I. Ansotegui, I.J. Baiardini, I. Bateman, E.D. Bedbrook, A. Beghé, B. Beji, M. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Bergmann, K.C. Berrissoul, F. Bieber, T. Bindslev Jensen, C. Blaiss, M.S. Boner, A.L. Bouchard, J. Braido, F. Brightling, C.E. Bush, A. Caballero, F. Calderon, M.A. Calvo, M.A. Camargos, P.A.M. Caraballo, L.R. Carlsen, K.H. Carr, W. Cepeda, A.M. Cesario, A. Chavannes, N.H. Chen, Y.Z. Chiriac, A.M. Chivato Pérez, T. Chkhartishvili, E. Ciprandi, G. Costa, D.J. Cox, L. Custovic, A. Dahl, R. Darsow, U. De Blay, F. Deleanu, D. Denburg, J.A. Devillier, P. Didi, T. Dokic, D. Dolen, W.K. Douagui, H. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. El-Meziane, A. Emuzyte, R. Fiocchi, A. Fletcher, M. Fukuda, T. Gamkrelidze, A. Gereda, J.E. González Diaz, S. Gotua, M. Guzmán, M.A. Hellings, P.W. Hellquist-Dahl, B. Horak, F. Hourihane, J.O'B. Howarth, P. Humbert, M. Ivancevich, J.C. Jackson, C. Just, J. Kalayci, O. Kaliner, M.A. Kalyoncu, A.F. Keil, T. Keith, P.K. Khayat, G. Kim, Y.Y. Koffi N'Goran, B. Koppelman, G.H. Kowalski, M.L. Kull, I. Kvedariene, V. Larenas-Linnemann, D. Le, L.T. Lemière, C. Li, J. Lieberman, P. Lipworth, B. Mahboub, B. Makela, M.J. Martin, F. Marshall, G.D. Martinez, F.D. Masjedi, M.R. Maurer, M. Mavale-Manuel, S. Mazon, A. Melen, E. Meltzer, E.O. Mendez, N.H. Merk, H. Mihaltan, F. Mohammad, Y. Morais-Almeida, M. Muraro, A. Nafti, S. Namazova-Baranova, L. Nekam, K. Neou, A. Niggemann, B. Nizankowska-Mogilnicka, E. Nyembue, T.D. Okamoto, Y. Okubo, K. Orru, M.P. Ouedraogo, S. Ozdemir, C. Panzner, P. Pali-Schöll, I. Park, H.S. Pigearias, B. Pohl, W. Popov, T.A. Postma, D.S. Potter, P. Rabe, K.F. Ratomaharo, J. Reitamo, S. Ring, J. Roberts, R. Rogala, B. Romano, A. Roman Rodriguez, M. Rosado-Pinto, J. Rosenwasser, L. Rottem, M. Sanchez-Borges, M. Scadding, G.K. Schmid-Grendelmeier, P. Sheikh, A. Sisul, J.C. Solé, D. Sooronbaev, T. Spicak, V. Spranger, O. Stein, R.T. Stoloff, S.W. Sunyer, J. Szczeklik, A. Todo-Bom, A. Toskala, E. Tremblay, Y. Valenta, R. Valero, A.L. Valeyre, D. Valiulis, A. Valovirta, E. Van Cauwenberge, P. Vandenplas, O. Van Weel, C. Vichyanond, P. Viegi, G. Wang, D.Y. Wickman, M. Wöhrl, S. Wright, J. Yawn, B.P. Yiallouros, P.K. Zar, H.J. Zernotti, M.E. Zhong, N. Zidarn, M. Zuberbier, T. Ang, C.S. Baigenzhin, A.K. Boakye, D.A. Briggs, A.H. Burney, P.G. Busse, W.W. Chuchalin, A.G. Haddad, H. Johnston, S.L. Kogevinas, M. Levy, M.L. Mohammadi, A. Oddie, S. Rezagui, D. Terreehorst, I. Warner, J.O.
- Abstract
Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children. © 2012 American Academy of Allergy, Asthma & Immunology.
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- 2012
17. Résistance à la rifampicine chez les patients suspects de tuberculose multi-résistante à Tamatave
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Razafindrakoto, L., primary, Andriamihaja, R., additional, and Ratomaharo, J., additional
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- 2015
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18. Manifestations des allergies nasosinusiennes sur les voies aériennes inférieures
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Andriamihaja, R., primary, Razafindrakoto, L., additional, Fidy Arson Lala, J., additional, Randriantahiry, M., additional, and Ratomaharo, J., additional
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- 2015
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19. L’asthme à Tamatave : selon les stades de sévérité
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Razafindrakoto, L., primary, Andriamihaja, R., additional, and Ratomaharo, J., additional
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- 2014
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20. Coïnfection tuberculose/VIH dans la ville de Toamasina
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Andriamihaja, R., primary, Razafindrakoto, L., additional, and Ratomaharo, J., additional
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- 2014
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- View/download PDF
21. Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.
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Bousquet, J., Anto, J.M., Demoly, P., Schunemann, H.J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P.J., Carlsen, K.H., Casale, T.B., Cruz, A.A., Keil, T., Lodrup Carlsen, K.C., Maurer, M., Ohta, K., Papadopoulos, N.G., Roman Rodriguez, M., Samolinski, B., Agache, I., Andrianarisoa, A., Ang, C.S., Annesi-Maesano, I., Ballester, F., Baena-Cagnani, C.E., Basagana, X., Bateman, E.D., Bel, E.H., Bedbrook, A., Beghe, B., Beji, M., Kheder, A. Ben, Benet, M., Bennoor, K.S., Bergmann, K.C., Berrissoul, F., Bindslev Jensen, C., Bleecker, E.R., Bonini, S., Boner, A.L., Boulet, L.P., Brightling, C.E., Brozek, J.L., Bush, A., Busse, W.W., Camargos, P.A., Canonica, G.W., Carr, W., Cesario, A., Chen, Y.Z., Chiriac, A.M., Costa, D.J., Cox, L., Custovic, A., Dahl, R., Darsow, U., Didi, T., Dolen, W.K., Douagui, H., Dubakiene, R., El-Meziane, A., Fonseca, J.A., Fokkens, W.J., Fthenou, E., Gamkrelidze, A., Garcia-Aymerich, J., Gerth van Wijk, R., Gimeno-Santos, E., Guerra, S., Haahtela, T., Haddad, H., Hellings, P.W., Hellquist-Dahl, B., Hohmann, C., Howarth, P., Hourihane, J.O., Humbert, M., Jacquemin, B., Just, J., Kalayci, O., Kaliner, M.A., Kauffmann, F., Kerkhof, M. van de, Khayat, G., Koffi N'Goran, B., Kogevinas, M., Koppelman, G.H., Kowalski, M.L., Kull, I., Kuna, P., Larenas, D., Lavi, I., Le, L.T., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M.J., Martin, F., Martinez, F.D., Marshall, G.D., Fatima Mazon, A. di, Melen, E., Meltzer, E.O., Mihaltan, F., Mohammad, Y., Mohammadi, A., Momas, I., Morais-Almeida, M., Mullol, J., Muraro, A., Naclerio, R., Nafti, S., Namazova-Baranova, L., Nawijn, M.C., Nyembue, T.D., Oddie, S., O'Hehir, R.E., Okamoto, Y., Orru, M.P., Ozdemir, C., Ouedraogo, G.S., Palkonen, S., Panzner, P., Passalacqua, G., Pawankar, R., Pigearias, B., Pin, I., Pinart, M., Pison, C., Popov, T.A., Porta, D., Postma, D.S., Price, D., Rabe, K.F., Ratomaharo, J., Reitamo, S., Rezagui, D., Ring, J., Roberts, R., Roca, J., Rogala, B., Romano, A., Rosado-Pinto, J., Ryan, D., Sanchez-Borges, M., Scadding, G.K., Sheikh, A., Simons, F.E., Siroux, V., Schmid-Grendelmeier, P.D., Smit, H.A., Sooronbaev, T., Stein, R.T., Sterk, P.J., Sunyer, J., Terreehorst, I., Toskala, E., Tremblay, Y., Valenta, R., Valeyre, D., Vandenplas, O., Weel, C. van, Vassilaki, M., Varraso, R., Viegi, G., Wang, D.Y., Wickman, M., Williams, D., Wohrl, S., Wright, J., Yorgancioglu, A., Yusuf, O.M., Zar, H.J., Zernotti, M.E., Zidarn, M., Zhong, N., Zuberbier, T., Bousquet, J., Anto, J.M., Demoly, P., Schunemann, H.J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P.J., Carlsen, K.H., Casale, T.B., Cruz, A.A., Keil, T., Lodrup Carlsen, K.C., Maurer, M., Ohta, K., Papadopoulos, N.G., Roman Rodriguez, M., Samolinski, B., Agache, I., Andrianarisoa, A., Ang, C.S., Annesi-Maesano, I., Ballester, F., Baena-Cagnani, C.E., Basagana, X., Bateman, E.D., Bel, E.H., Bedbrook, A., Beghe, B., Beji, M., Kheder, A. Ben, Benet, M., Bennoor, K.S., Bergmann, K.C., Berrissoul, F., Bindslev Jensen, C., Bleecker, E.R., Bonini, S., Boner, A.L., Boulet, L.P., Brightling, C.E., Brozek, J.L., Bush, A., Busse, W.W., Camargos, P.A., Canonica, G.W., Carr, W., Cesario, A., Chen, Y.Z., Chiriac, A.M., Costa, D.J., Cox, L., Custovic, A., Dahl, R., Darsow, U., Didi, T., Dolen, W.K., Douagui, H., Dubakiene, R., El-Meziane, A., Fonseca, J.A., Fokkens, W.J., Fthenou, E., Gamkrelidze, A., Garcia-Aymerich, J., Gerth van Wijk, R., Gimeno-Santos, E., Guerra, S., Haahtela, T., Haddad, H., Hellings, P.W., Hellquist-Dahl, B., Hohmann, C., Howarth, P., Hourihane, J.O., Humbert, M., Jacquemin, B., Just, J., Kalayci, O., Kaliner, M.A., Kauffmann, F., Kerkhof, M. van de, Khayat, G., Koffi N'Goran, B., Kogevinas, M., Koppelman, G.H., Kowalski, M.L., Kull, I., Kuna, P., Larenas, D., Lavi, I., Le, L.T., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M.J., Martin, F., Martinez, F.D., Marshall, G.D., Fatima Mazon, A. di, Melen, E., Meltzer, E.O., Mihaltan, F., Mohammad, Y., Mohammadi, A., Momas, I., Morais-Almeida, M., Mullol, J., Muraro, A., Naclerio, R., Nafti, S., Namazova-Baranova, L., Nawijn, M.C., Nyembue, T.D., Oddie, S., O'Hehir, R.E., Okamoto, Y., Orru, M.P., Ozdemir, C., Ouedraogo, G.S., Palkonen, S., Panzner, P., Passalacqua, G., Pawankar, R., Pigearias, B., Pin, I., Pinart, M., Pison, C., Popov, T.A., Porta, D., Postma, D.S., Price, D., Rabe, K.F., Ratomaharo, J., Reitamo, S., Rezagui, D., Ring, J., Roberts, R., Roca, J., Rogala, B., Romano, A., Rosado-Pinto, J., Ryan, D., Sanchez-Borges, M., Scadding, G.K., Sheikh, A., Simons, F.E., Siroux, V., Schmid-Grendelmeier, P.D., Smit, H.A., Sooronbaev, T., Stein, R.T., Sterk, P.J., Sunyer, J., Terreehorst, I., Toskala, E., Tremblay, Y., Valenta, R., Valeyre, D., Vandenplas, O., Weel, C. van, Vassilaki, M., Varraso, R., Viegi, G., Wang, D.Y., Wickman, M., Williams, D., Wohrl, S., Wright, J., Yorgancioglu, A., Yusuf, O.M., Zar, H.J., Zernotti, M.E., Zidarn, M., Zhong, N., and Zuberbier, T.
- Abstract
Item does not contain fulltext, Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies.
- Published
- 2012
22. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs.
- Author
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UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J, Schünemann, H J, Samolinski, B, Demoly, P, Baena-Cagnani, C E, Bachert, C, Bonini, S, Boulet, L P, Bousquet, P J, Brozek, J L, Canonica, G W, Casale, T B, Cruz, A A, Fokkens, W J, Fonseca, J A, van Wijk, R Gerth, Grouse, L, Haahtela, T, Khaltaev, N, Kuna, P, Lockey, R F, Lodrup Carlsen, K C, Mullol, J, Naclerio, R, O'Hehir, R E, Ohta, K, Palkonen, S, Papadopoulos, N G, Passalacqua, G, Pawankar, R, Price, D, Ryan, D, Simons, F E R, Togias, A, Williams, D, Yorgancioglu, A., Yusuf, O M, Aberer, W, Adachi, M, Agache, I, Aït-Khaled, N, Akdis, C A, Andrianarisoa, A, Annesi-Maesano, I, Ansotegui, I J, Baiardini, I, Bateman, E D, Bedbrook, A, Beghé, B, Beji, M, Bel, E H, Ben Kheder, A, Bennoor, K S, Bergmann, K C, Berrissoul, F, Bieber, T, Bindslev Jensen, C, Blaiss, M S, Boner, A L, Bouchard, J, Braido, F, Brightling, C E, Bush, A, Caballero, F, Calderon, M A, Calvo, M A, Camargos, P A M, Caraballo, L R, Carlsen, K H, Carr, W, Cepeda, A M, Cesario, A, Chavannes, N H, Chen, Y Z, Chiriac, A M, Chivato Pérez, T, Chkhartishvili, E, Ciprandi, G, Costa, D J, Cox, L, Custovic, A, Dahl, R, Darsow, U, De Blay, F, Deleanu, D, Denburg, J A, Devillier, P, Didi, T, Dokic, D, Dolen, W K, Douagui, H, Dubakiene, R, Durham, S R, Dykewicz, M S, El-Gamal, Y, El-Meziane, A, Emuzyte, R, Fiocchi, A, Fletcher, M, Fukuda, T, Gamkrelidze, A, Gereda, J E, González Diaz, S, Gotua, M, Guzmán, M A, Hellings, P W, Hellquist-Dahl, B, Horak, F, Hourihane, J O'B, Howarth, P, Humbert, M, Ivancevich, J C, Jackson, C, Just, J, Kalayci, O, Kaliner, M A, Kalyoncu, A F, Keil, T, Keith, P K, Khayat, G, Kim, Y Y, Koffi N'goran, B, Koppelman, G H, Kowalski, M L, Kull, I, Kvedariene, V, Larenas-Linnemann, D, Le, L T, Lemière, C, Li, J, Lieberman, P, Lipworth, B, Mahboub, B, Makela, M J, Martin, F, Marshall, G D, Martinez, F D, Masjedi, M R, Maurer, M, Mavale-Manuel, S, Mazon, A, Melen, E, Meltzer, E O, Mendez, N H, Merk, H, Mihaltan, F, Mohammad, Y, Morais-Almeida, M, Muraro, A, Nafti, S, Namazova-Baranova, L, Nekam, K, Neou, A, Niggemann, B, Nizankowska-Mogilnicka, E, Nyembue, T D, Okamoto, Y, Okubo, K, Orru, M P, Ouedraogo, S, Ozdemir, C, Panzner, P, Pali-Schöll, I, Park, H S, Pigearias, B, Pohl, W, Popov, T A, Postma, D S, Potter, P, Rabe, K F, Ratomaharo, J, Reitamo, S, Ring, J, Roberts, R, Rogala, B, Romano, A, Roman Rodriguez, M, Rosado-Pinto, J, Rosenwasser, L, Rottem, M, Sanchez-Borges, M, Scadding, G K, Schmid-Grendelmeier, P, Sheikh, A, Sisul, J C, Solé, D, Sooronbaev, T, Spicak, V, Spranger, O, Stein, R T, Stoloff, S W, Sunyer, J, Szczeklik, A, Todo-Bom, A, Toskala, E, Tremblay, Y, Valenta, R, Valero, A L, Valeyre, D, Valiulis, A, Valovirta, E, Van Cauwenberge, P, Vandenplas, Olivier, van Weel, C, Vichyanond, P, Viegi, G, Wang, D Y, Wickman, M, Wöhrl, S, Wright, J, Yawn, B P, Yiallouros, P K, Zar, H J, Zernotti, M E, Zhong, N, Zidarn, M, Zuberbier, T, Burney, P G, Johnston, S L, Warner, J O, UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J, Schünemann, H J, Samolinski, B, Demoly, P, Baena-Cagnani, C E, Bachert, C, Bonini, S, Boulet, L P, Bousquet, P J, Brozek, J L, Canonica, G W, Casale, T B, Cruz, A A, Fokkens, W J, Fonseca, J A, van Wijk, R Gerth, Grouse, L, Haahtela, T, Khaltaev, N, Kuna, P, Lockey, R F, Lodrup Carlsen, K C, Mullol, J, Naclerio, R, O'Hehir, R E, Ohta, K, Palkonen, S, Papadopoulos, N G, Passalacqua, G, Pawankar, R, Price, D, Ryan, D, Simons, F E R, Togias, A, Williams, D, Yorgancioglu, A., Yusuf, O M, Aberer, W, Adachi, M, Agache, I, Aït-Khaled, N, Akdis, C A, Andrianarisoa, A, Annesi-Maesano, I, Ansotegui, I J, Baiardini, I, Bateman, E D, Bedbrook, A, Beghé, B, Beji, M, Bel, E H, Ben Kheder, A, Bennoor, K S, Bergmann, K C, Berrissoul, F, Bieber, T, Bindslev Jensen, C, Blaiss, M S, Boner, A L, Bouchard, J, Braido, F, Brightling, C E, Bush, A, Caballero, F, Calderon, M A, Calvo, M A, Camargos, P A M, Caraballo, L R, Carlsen, K H, Carr, W, Cepeda, A M, Cesario, A, Chavannes, N H, Chen, Y Z, Chiriac, A M, Chivato Pérez, T, Chkhartishvili, E, Ciprandi, G, Costa, D J, Cox, L, Custovic, A, Dahl, R, Darsow, U, De Blay, F, Deleanu, D, Denburg, J A, Devillier, P, Didi, T, Dokic, D, Dolen, W K, Douagui, H, Dubakiene, R, Durham, S R, Dykewicz, M S, El-Gamal, Y, El-Meziane, A, Emuzyte, R, Fiocchi, A, Fletcher, M, Fukuda, T, Gamkrelidze, A, Gereda, J E, González Diaz, S, Gotua, M, Guzmán, M A, Hellings, P W, Hellquist-Dahl, B, Horak, F, Hourihane, J O'B, Howarth, P, Humbert, M, Ivancevich, J C, Jackson, C, Just, J, Kalayci, O, Kaliner, M A, Kalyoncu, A F, Keil, T, Keith, P K, Khayat, G, Kim, Y Y, Koffi N'goran, B, Koppelman, G H, Kowalski, M L, Kull, I, Kvedariene, V, Larenas-Linnemann, D, Le, L T, Lemière, C, Li, J, Lieberman, P, Lipworth, B, Mahboub, B, Makela, M J, Martin, F, Marshall, G D, Martinez, F D, Masjedi, M R, Maurer, M, Mavale-Manuel, S, Mazon, A, Melen, E, Meltzer, E O, Mendez, N H, Merk, H, Mihaltan, F, Mohammad, Y, Morais-Almeida, M, Muraro, A, Nafti, S, Namazova-Baranova, L, Nekam, K, Neou, A, Niggemann, B, Nizankowska-Mogilnicka, E, Nyembue, T D, Okamoto, Y, Okubo, K, Orru, M P, Ouedraogo, S, Ozdemir, C, Panzner, P, Pali-Schöll, I, Park, H S, Pigearias, B, Pohl, W, Popov, T A, Postma, D S, Potter, P, Rabe, K F, Ratomaharo, J, Reitamo, S, Ring, J, Roberts, R, Rogala, B, Romano, A, Roman Rodriguez, M, Rosado-Pinto, J, Rosenwasser, L, Rottem, M, Sanchez-Borges, M, Scadding, G K, Schmid-Grendelmeier, P, Sheikh, A, Sisul, J C, Solé, D, Sooronbaev, T, Spicak, V, Spranger, O, Stein, R T, Stoloff, S W, Sunyer, J, Szczeklik, A, Todo-Bom, A, Toskala, E, Tremblay, Y, Valenta, R, Valero, A L, Valeyre, D, Valiulis, A, Valovirta, E, Van Cauwenberge, P, Vandenplas, Olivier, van Weel, C, Vichyanond, P, Viegi, G, Wang, D Y, Wickman, M, Wöhrl, S, Wright, J, Yawn, B P, Yiallouros, P K, Zar, H J, Zernotti, M E, Zhong, N, Zidarn, M, Zuberbier, T, Burney, P G, Johnston, S L, and Warner, J O
- Abstract
Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children.
- Published
- 2012
23. Severe chronic allergic (and related) diseases: A uniform approach - A MeDALL - GA 2 LEN - ARIA position paper
- Author
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UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J., Anto, J.M., Demoly, P., Schünemann, H.J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P.J., Carlsen, K.H., Casale, T.B., Cruz, A.A., Keil, T., Lodrup Carlsen, K.C., Maurer, M., Ohta, K., Papadopoulos, N.G., Roman Rodriguez, M., Samolinski, B., Agache, I., Andrianarisoa, A., Ang, C.S., Annesi-Maesano, I., Ballester, F., Baena-Cagnani, C.E., Basagaña, X., Bateman, E.D., Bel, E.H., Bedbrook, A., Beghé, B., Beji, M., Ben Kheder, A., Benet, M., Bennoor, K.S., Bergmann, K.C., Berrissoul, F., Bindslev Jensen, C., Bleecker, E.R., Bonini, S., Boner, A.L., Boulet, L.P., Brightling, C.E., Brozek, J.L., Bush, A., Busse, W.W., Camargos, P.A.M., Canonica, G.W., Carr, W., Cesario, A., Chen, Y.Z., Chiriac, A.M., Costa, D.J., Cox, L., Custovic, A., Dahl, R., Darsow, U., Didi, T., Dolen, W.K., Douagui, H., Dubakiene, R., El-Meziane, A., Fonseca, J.A., Fokkens, W.J., Fthenou, E., Gamkrelidze, A., Garcia-Aymerich, J., Van Wijk, R.G., Gimeno-Santos, E., Guerra, S., Haahtela, T., Haddad, H., Hellings, P.W., Hellquist-Dahl, B., Hohmann, C., Howarth, P., Hourihane, J.O., Humbert, M., Jacquemin, B., Just, J., Kalayci, O., Kaliner, M.A., Kauffmann, F., Kerkhof, M., Khayat, G., Koffi N'Goran, B., Kogevinas, M., Koppelman, G.H., Kowalski, M.L., Kull, I., Kuna, P., Larenas, D., Lavi, I., Le, L.T., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M.J., Martin, F., Martinez, F.D., Marshall, G.D., Mazon, A., Melen, E., Meltzer, E.O., Mihaltan, F., Mohammad, Y., Mohammadi, A., Momas, I., Morais-Almeida, M., Mullol, J., Muraro, A., Naclerio, R., Nafti, S., Namazova-Baranova, L., Nawijn, M.C., Nyembue, T.D., Oddie, S., O'Hehir, R.E., Okamoto, Y., Orru, M.P., Ozdemir, C., Ouedraogo, G.S., Palkonen, S., Panzner, P., Passalacqua, G., Pawankar, R., Pigearias, B., Pin, I., Pinart, M., Pison, C., Popov, T.A., Porta, D., Postma, D.S., Price, D., Rabe, K.F., Ratomaharo, J., Reitamo, S., Rezagui, D., Ring, J., Roberts, R., Roca, J., Rogala, B., Romano, A., Rosado-Pinto, J., Ryan, D., Sanchez-Borges, M., Scadding, G.K., Sheikh, A., Simons, F.E.R., Siroux, V., Schmid-Grendelmeier, P.D., Smit, H.A., Sooronbaev, T., Stein, R.T., Sterk, P.J., Sunyer, J., Terreehorst, I., Toskala, E., Tremblay, Y., Valenta, R., Valeyre, D., Vandenplas, Olivier, Van Weel, C., Vassilaki, M., Varraso, R., Viegi, G., Wang, D.Y., Wickman, M., Williams, D., Wöhrl, S., Wright, J., Yorgancioglu, A., Yusuf, O M, Zar, H.J., Zernotti, M.E., Zidarn, M., Zhong, N., Zuberbier, T., UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J., Anto, J.M., Demoly, P., Schünemann, H.J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P.J., Carlsen, K.H., Casale, T.B., Cruz, A.A., Keil, T., Lodrup Carlsen, K.C., Maurer, M., Ohta, K., Papadopoulos, N.G., Roman Rodriguez, M., Samolinski, B., Agache, I., Andrianarisoa, A., Ang, C.S., Annesi-Maesano, I., Ballester, F., Baena-Cagnani, C.E., Basagaña, X., Bateman, E.D., Bel, E.H., Bedbrook, A., Beghé, B., Beji, M., Ben Kheder, A., Benet, M., Bennoor, K.S., Bergmann, K.C., Berrissoul, F., Bindslev Jensen, C., Bleecker, E.R., Bonini, S., Boner, A.L., Boulet, L.P., Brightling, C.E., Brozek, J.L., Bush, A., Busse, W.W., Camargos, P.A.M., Canonica, G.W., Carr, W., Cesario, A., Chen, Y.Z., Chiriac, A.M., Costa, D.J., Cox, L., Custovic, A., Dahl, R., Darsow, U., Didi, T., Dolen, W.K., Douagui, H., Dubakiene, R., El-Meziane, A., Fonseca, J.A., Fokkens, W.J., Fthenou, E., Gamkrelidze, A., Garcia-Aymerich, J., Van Wijk, R.G., Gimeno-Santos, E., Guerra, S., Haahtela, T., Haddad, H., Hellings, P.W., Hellquist-Dahl, B., Hohmann, C., Howarth, P., Hourihane, J.O., Humbert, M., Jacquemin, B., Just, J., Kalayci, O., Kaliner, M.A., Kauffmann, F., Kerkhof, M., Khayat, G., Koffi N'Goran, B., Kogevinas, M., Koppelman, G.H., Kowalski, M.L., Kull, I., Kuna, P., Larenas, D., Lavi, I., Le, L.T., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M.J., Martin, F., Martinez, F.D., Marshall, G.D., Mazon, A., Melen, E., Meltzer, E.O., Mihaltan, F., Mohammad, Y., Mohammadi, A., Momas, I., Morais-Almeida, M., Mullol, J., Muraro, A., Naclerio, R., Nafti, S., Namazova-Baranova, L., Nawijn, M.C., Nyembue, T.D., Oddie, S., O'Hehir, R.E., Okamoto, Y., Orru, M.P., Ozdemir, C., Ouedraogo, G.S., Palkonen, S., Panzner, P., Passalacqua, G., Pawankar, R., Pigearias, B., Pin, I., Pinart, M., Pison, C., Popov, T.A., Porta, D., Postma, D.S., Price, D., Rabe, K.F., Ratomaharo, J., Reitamo, S., Rezagui, D., Ring, J., Roberts, R., Roca, J., Rogala, B., Romano, A., Rosado-Pinto, J., Ryan, D., Sanchez-Borges, M., Scadding, G.K., Sheikh, A., Simons, F.E.R., Siroux, V., Schmid-Grendelmeier, P.D., Smit, H.A., Sooronbaev, T., Stein, R.T., Sterk, P.J., Sunyer, J., Terreehorst, I., Toskala, E., Tremblay, Y., Valenta, R., Valeyre, D., Vandenplas, Olivier, Van Weel, C., Vassilaki, M., Varraso, R., Viegi, G., Wang, D.Y., Wickman, M., Williams, D., Wöhrl, S., Wright, J., Yorgancioglu, A., Yusuf, O M, Zar, H.J., Zernotti, M.E., Zidarn, M., Zhong, N., and Zuberbier, T.
- Abstract
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright © 2012 S. Karger AG, Basel.
- Published
- 2012
24. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs
- Author
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Bousquet, Jean, Schünemann, Holger J., Samolinski, Boleslaw, Demoly, Pascal, Baena Cagnani, Carlos E., Bachert, Claus, Bonini, Sergio, Boulet, Louis Philippe, Bousquet, Philippe J., Brozek, Jan L., Canonica, Giorgio Walter, Casale, Thomas B., Cruz, A. A., Fokkens, Wytske J., Fonseca, Joao A., van Wijk, R. Gerth, Grouse, Lawrence, Haahtela, Tari, Khaltaev, Nikolai, Kuna, Piotr, Lockey, R.F., Lodrup Carlsen, Karin C., Mullol, Jaoquim, Naclerio, Robert N., O'Hehir, Robyn E., Ohta, Ken, Palkonen, Susanna, Papadopoulos, Nikolaos G., Passalacqua, Giovanni, Pawankar, Ruby, Price, David, Ryan, Dermot, Simons, F. Estelle R., Togias, A., Williams, D. M., Yorgancioglu, Arzu, Yusuf, Osman M., Aberer, Werner, Adachi, Mitsuru, Agache, Ioana, Aït Khaled, Nadia, Akdis, Cezmi, Andrianarisoa, A., Annesi Maesano, Isabella, Ansotegui, Ignacio J., Baiardini, Ilaria, Bateman, Eric D., Bedbrook, Anna, Beghé, Bianca, Beji, M., Bel, Elisabeth H., Ben Kheder, Ali, Bennoor, Kazi S., Bergmann, Karl Christian, Berrissoul, F., Bieber, T., Bindslev Jensen, Carsten, Blaiss, M.S., Boner, A. L., Bouchard, Jacques, Braido, Fulvio, Brightling, Christopher E., Bush, Andrew, Caballero Fonseca, Fernando, Calderon, M. A., Calvo, M.A., Camargos, P. A. M., Caraballo, Luis R., Carlsen, Kai Hakon, Carr, Warner, Cepeda, A.M., Cesario, A., Chavannes, Niels H., Chen, Yuzhi Z., Chiriac, A.M., Chivato Pérez, T., Chkhartishvili, Ekaterine, Ciprandi, Georgio, Costa, David J., Cox, Linda, Custovic, Adnan, Dahl, Ronald, Darsow, Ulf, De Blay, Frédéric, Deleanu, Diana, Denburg, J. A., Devillier, Phillipe, Didi, T., Dokic, Dejan, Dolen, W.K., Douagui, Habib B., Dubakiene, Ruta, Durham, S. R., Dykewicz, Mark S., El Gamal, Yehia, El Meziane, A., Emuzyte, R., Fiocchi, Alessandro, Fletcher, Monica, Fukuda, T., Gamkrelidze, Amiran, Gereda, José E., González Díaz, Sandra Nora, Gotua, Maia, Guzmán Meléndez, María Antonieta, Hellings, Peter W., Hellquist Dahl, Birthe, Horak, Friedrich, Hourihane, J. O’. B., Howarth, Peter H., Humbert, Marc, Ivancevich, Juan Carlos, Jackson, C., Just, Jocelyne, Kalayci, Omer, Kaliner, M.A., Kalyoncu, A. F., Keil, Thomas, Keith, Paul K., Khayat, G., Kim, Y. Y., Koffi N'Goran, B., Koppelman, Gerard H., Kowalski, Marek L., Kull, Inger, Kvedariene, Violeta, Larenas Linnemann, Désirée, Le, L. T. T., Lemière, C., Li, Jingmei, Lieberman, Phillipe, Lipworth, Brian J., Mahboub, Bassam, Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, Mohamad R., Maurer, Marcus, Mavale Manuel, Sandra, Mazon, A., Melén, Erik, Meltzer, E. O., Mendez, N. H., Merk, Hans, Mihaltan, Florin, Mohammad, Yousser, Morais Almeida, Mario, Muraro, Antonella, Nafti, S., Namazova Baranova, Leyla, Nekam, Kristof, Neou, Angelos, Niggemann, Bodo, Nizankowska Mogilnicka, E., Nyembue, T. Dieudonné, Okamoto, Yoshitaka, Okubo, Kim, Orru, M.P., Ouedraogo, Solange, Ozdemir, C., Panzner, Petr, Pali Schöll, Isabella, Park, Hae-Sim, Pigearias, Bernard, Pohl, Wolfgang, Popov, Todor A., Postma, Dirkje S., Potter, Paul, Rabe, Klaus F., Ratomaharo, J., Reitamo, Sakari, Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado Pinto, José, Rosenwasser, Larry, Rottem, Menachem, Sánchez Borges, Mario, Scadding, Glenis K., Schmid Grendelmeier, Peter, Sheikh, Aziz, Sisul Alvariza, Juan Carlos, Solé, Dirceu, Sooronbaev, Talant, Spicak, Václav, Spranger, Otto, Stein, R. T., Stoloff, S. W., Sunyer, Jordi, Szczeklik, A., Todo Bom, Ana Maria, Toskala, E., Tremblay, Y., Valenta, Rudolf, Valero, Antonio L., Valeyre, D., Valiulis, Arunas, Valovirta, Erkka, Van Cauwenberge, P., Vandenplas, Olivier, Van Weel, Chris, Vichyanond, Pakit, Viegi, Giovanni, Wang, D. Y., Wickman, Magnus, Wöhrl, S., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Zar, Heather J., Zernotti, Mario, Zhong, Nanshan, Zidarn, Mihaela, Zuberbier, Torsten, Bousquet, Jean, Schünemann, Holger J., Samolinski, Boleslaw, Demoly, Pascal, Baena Cagnani, Carlos E., Bachert, Claus, Bonini, Sergio, Boulet, Louis Philippe, Bousquet, Philippe J., Brozek, Jan L., Canonica, Giorgio Walter, Casale, Thomas B., Cruz, A. A., Fokkens, Wytske J., Fonseca, Joao A., van Wijk, R. Gerth, Grouse, Lawrence, Haahtela, Tari, Khaltaev, Nikolai, Kuna, Piotr, Lockey, R.F., Lodrup Carlsen, Karin C., Mullol, Jaoquim, Naclerio, Robert N., O'Hehir, Robyn E., Ohta, Ken, Palkonen, Susanna, Papadopoulos, Nikolaos G., Passalacqua, Giovanni, Pawankar, Ruby, Price, David, Ryan, Dermot, Simons, F. Estelle R., Togias, A., Williams, D. M., Yorgancioglu, Arzu, Yusuf, Osman M., Aberer, Werner, Adachi, Mitsuru, Agache, Ioana, Aït Khaled, Nadia, Akdis, Cezmi, Andrianarisoa, A., Annesi Maesano, Isabella, Ansotegui, Ignacio J., Baiardini, Ilaria, Bateman, Eric D., Bedbrook, Anna, Beghé, Bianca, Beji, M., Bel, Elisabeth H., Ben Kheder, Ali, Bennoor, Kazi S., Bergmann, Karl Christian, Berrissoul, F., Bieber, T., Bindslev Jensen, Carsten, Blaiss, M.S., Boner, A. L., Bouchard, Jacques, Braido, Fulvio, Brightling, Christopher E., Bush, Andrew, Caballero Fonseca, Fernando, Calderon, M. A., Calvo, M.A., Camargos, P. A. M., Caraballo, Luis R., Carlsen, Kai Hakon, Carr, Warner, Cepeda, A.M., Cesario, A., Chavannes, Niels H., Chen, Yuzhi Z., Chiriac, A.M., Chivato Pérez, T., Chkhartishvili, Ekaterine, Ciprandi, Georgio, Costa, David J., Cox, Linda, Custovic, Adnan, Dahl, Ronald, Darsow, Ulf, De Blay, Frédéric, Deleanu, Diana, Denburg, J. A., Devillier, Phillipe, Didi, T., Dokic, Dejan, Dolen, W.K., Douagui, Habib B., Dubakiene, Ruta, Durham, S. R., Dykewicz, Mark S., El Gamal, Yehia, El Meziane, A., Emuzyte, R., Fiocchi, Alessandro, Fletcher, Monica, Fukuda, T., Gamkrelidze, Amiran, Gereda, José E., González Díaz, Sandra Nora, Gotua, Maia, Guzmán Meléndez, María Antonieta, Hellings, Peter W., Hellquist Dahl, Birthe, Horak, Friedrich, Hourihane, J. O’. B., Howarth, Peter H., Humbert, Marc, Ivancevich, Juan Carlos, Jackson, C., Just, Jocelyne, Kalayci, Omer, Kaliner, M.A., Kalyoncu, A. F., Keil, Thomas, Keith, Paul K., Khayat, G., Kim, Y. Y., Koffi N'Goran, B., Koppelman, Gerard H., Kowalski, Marek L., Kull, Inger, Kvedariene, Violeta, Larenas Linnemann, Désirée, Le, L. T. T., Lemière, C., Li, Jingmei, Lieberman, Phillipe, Lipworth, Brian J., Mahboub, Bassam, Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, Mohamad R., Maurer, Marcus, Mavale Manuel, Sandra, Mazon, A., Melén, Erik, Meltzer, E. O., Mendez, N. H., Merk, Hans, Mihaltan, Florin, Mohammad, Yousser, Morais Almeida, Mario, Muraro, Antonella, Nafti, S., Namazova Baranova, Leyla, Nekam, Kristof, Neou, Angelos, Niggemann, Bodo, Nizankowska Mogilnicka, E., Nyembue, T. Dieudonné, Okamoto, Yoshitaka, Okubo, Kim, Orru, M.P., Ouedraogo, Solange, Ozdemir, C., Panzner, Petr, Pali Schöll, Isabella, Park, Hae-Sim, Pigearias, Bernard, Pohl, Wolfgang, Popov, Todor A., Postma, Dirkje S., Potter, Paul, Rabe, Klaus F., Ratomaharo, J., Reitamo, Sakari, Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado Pinto, José, Rosenwasser, Larry, Rottem, Menachem, Sánchez Borges, Mario, Scadding, Glenis K., Schmid Grendelmeier, Peter, Sheikh, Aziz, Sisul Alvariza, Juan Carlos, Solé, Dirceu, Sooronbaev, Talant, Spicak, Václav, Spranger, Otto, Stein, R. T., Stoloff, S. W., Sunyer, Jordi, Szczeklik, A., Todo Bom, Ana Maria, Toskala, E., Tremblay, Y., Valenta, Rudolf, Valero, Antonio L., Valeyre, D., Valiulis, Arunas, Valovirta, Erkka, Van Cauwenberge, P., Vandenplas, Olivier, Van Weel, Chris, Vichyanond, Pakit, Viegi, Giovanni, Wang, D. Y., Wickman, Magnus, Wöhrl, S., Wright, John, Yawn, Barbara P., Yiallouros, P. K., Zar, Heather J., Zernotti, Mario, Zhong, Nanshan, Zidarn, Mihaela, and Zuberbier, Torsten
- Published
- 2012
25. L’application des normes spirométriques malgaches dans la population malgache atteinte de BPCO modifiera-t-elle sa stadification ?
- Author
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Razafindrakoto, L., primary, Andriamihaja, R., additional, Rakoto, S.L., additional, Randriantahiry, M., additional, and Ratomaharo, J., additional
- Published
- 2013
- Full Text
- View/download PDF
26. Émanation accidentelle de dioxyde de soufre (SO2) provenant d’une usine d’extraction de cobalt et de nickel
- Author
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Andriamihaja, R., primary, Razafindrakoto, L., additional, and Ratomaharo, J., additional
- Published
- 2013
- Full Text
- View/download PDF
27. Premières applications de la thermocoagulation bronchique à Madagascar
- Author
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Andriamihaja, R., primary, Razafindrakoto, L., additional, and Ratomaharo, J., additional
- Published
- 2013
- Full Text
- View/download PDF
28. Spirometric Reference Equations of the Adult Malagasy Population.
- Author
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Ratomaharo, J, primary, Randrianarivelo, O, additional, Andriamihaja, R, additional, Randriatahiry, M, additional, and Rakotosihanaka, F, additional
- Published
- 2009
- Full Text
- View/download PDF
29. Spirometric reference values for Malagasy adults aged 18-73 years.
- Author
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Ratomaharo J, Linares Perdomo O, Collingridge DS, Andriamihaja R, Hegewald M, Jensen RL, Hankinson J, and Morris AH
- Subjects
- Adolescent, Adult, Black or African American statistics & numerical data, Age Factors, Aged, Anthropometry, Cohort Studies, Developing Countries, Female, Healthy Volunteers, Humans, Linear Models, Madagascar, Male, Middle Aged, Multivariate Analysis, Predictive Value of Tests, Sex Factors, White People statistics & numerical data, Young Adult, Aging physiology, Forced Expiratory Volume physiology, Respiratory Mechanics physiology, Spirometry methods
- Abstract
The American Thoracic Society (ATS) and European Respiratory Society (ERS) recommend that spirometry prediction equations be derived from samples of similar race/ethnicity. Malagasy prediction equations do not exist. The objectives of this study were to establish prediction equations for healthy Malagasy adults, and then compare Malagasy measurements with published prediction equations. We enrolled 2491 healthy Malagasy subjects aged 18-73 years (1428 males) from June 2006 to April 2008. The subjects attempted to meet the ATS/ERS 2005 guidelines when performing forced expiratory spirograms. We compared Malagasy measurements of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC with predictions from the European Community for Steel and Coal (ECSC), the third National Health and Nutrition Examination Survey (NHANES III) and the ERS Global Lung Function Initiative (GLI) 2012 study. A linear model for the entire population, using age and height as independent variables, best predicted all spirometry parameters for sea level and highland subjects. FEV1, FVC and FEV1/FVC were most accurately predicted by NHANES III African-American male and female, and by GLI 2012 black male and black and South East Asian female equations. ECSC-predicted FEV1, FVC and FEV1/FVC were poorly matched to Malagasy measurements. We provide the first spirometry reference equations for a healthy adult Malagasy population, and the first comparison of Malagasy population measurements with ECSC, NHANES III and GLI 2012 prediction equations., (Copyright ©ERS 2015.)
- Published
- 2015
- Full Text
- View/download PDF
30. Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.
- Author
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Bousquet J, Anto JM, Demoly P, Schünemann HJ, Togias A, Akdis M, Auffray C, Bachert C, Bieber T, Bousquet PJ, Carlsen KH, Casale TB, Cruz AA, Keil T, Lodrup Carlsen KC, Maurer M, Ohta K, Papadopoulos NG, Roman Rodriguez M, Samolinski B, Agache I, Andrianarisoa A, Ang CS, Annesi-Maesano I, Ballester F, Baena-Cagnani CE, Basagaña X, Bateman ED, Bel EH, Bedbrook A, Beghé B, Beji M, Ben Kheder A, Benet M, Bennoor KS, Bergmann KC, Berrissoul F, Bindslev Jensen C, Bleecker ER, Bonini S, Boner AL, Boulet LP, Brightling CE, Brozek JL, Bush A, Busse WW, Camargos PA, Canonica GW, Carr W, Cesario A, Chen YZ, Chiriac AM, Costa DJ, Cox L, Custovic A, Dahl R, Darsow U, Didi T, Dolen WK, Douagui H, Dubakiene R, El-Meziane A, Fonseca JA, Fokkens WJ, Fthenou E, Gamkrelidze A, Garcia-Aymerich J, Gerth van Wijk R, Gimeno-Santos E, Guerra S, Haahtela T, Haddad H, Hellings PW, Hellquist-Dahl B, Hohmann C, Howarth P, Hourihane JO, Humbert M, Jacquemin B, Just J, Kalayci O, Kaliner MA, Kauffmann F, Kerkhof M, Khayat G, Koffi N'Goran B, Kogevinas M, Koppelman GH, Kowalski ML, Kull I, Kuna P, Larenas D, Lavi I, Le LT, Lieberman P, Lipworth B, Mahboub B, Makela MJ, Martin F, Martinez FD, Marshall GD, Mazon A, Melen E, Meltzer EO, Mihaltan F, Mohammad Y, Mohammadi A, Momas I, Morais-Almeida M, Mullol J, Muraro A, Naclerio R, Nafti S, Namazova-Baranova L, Nawijn MC, Nyembue TD, Oddie S, O'Hehir RE, Okamoto Y, Orru MP, Ozdemir C, Ouedraogo GS, Palkonen S, Panzner P, Passalacqua G, Pawankar R, Pigearias B, Pin I, Pinart M, Pison C, Popov TA, Porta D, Postma DS, Price D, Rabe KF, Ratomaharo J, Reitamo S, Rezagui D, Ring J, Roberts R, Roca J, Rogala B, Romano A, Rosado-Pinto J, Ryan D, Sanchez-Borges M, Scadding GK, Sheikh A, Simons FE, Siroux V, Schmid-Grendelmeier PD, Smit HA, Sooronbaev T, Stein RT, Sterk PJ, Sunyer J, Terreehorst I, Toskala E, Tremblay Y, Valenta R, Valeyre D, Vandenplas O, van Weel C, Vassilaki M, Varraso R, Viegi G, Wang DY, Wickman M, Williams D, Wöhrl S, Wright J, Yorgancioglu A, Yusuf OM, Zar HJ, Zernotti ME, Zidarn M, Zhong N, and Zuberbier T
- Subjects
- Asthma therapy, Chronic Disease, Comorbidity, Dermatitis, Atopic complications, Humans, Hypersensitivity epidemiology, Rhinitis complications, Rhinitis epidemiology, Sinusitis complications, Sinusitis epidemiology, Urticaria complications, Urticaria epidemiology, Asthma physiopathology, Hypersensitivity complications, Practice Guidelines as Topic standards, Severity of Illness Index
- Abstract
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies., (Copyright © 2012 S. Karger AG, Basel.)
- Published
- 2012
- Full Text
- View/download PDF
31. Evolution of physiological variables in patients with chronic obstructive pulmonary disease before and during long-term oxygen therapy.
- Author
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Weitzenblum E, Oswald M, Apprill M, Ratomaharo J, and Kessler R
- Subjects
- Blood Pressure, Carbon Dioxide blood, Forced Expiratory Volume, Humans, Lung Diseases, Obstructive blood, Lung Diseases, Obstructive therapy, Oxygen blood, Pulmonary Artery, Time Factors, Vital Capacity, Lung Diseases, Obstructive physiopathology, Oxygen Inhalation Therapy
- Abstract
In 24 patients with severe chronic obstructive pulmonary disease (COPD), we investigated the evolution of pulmonary volumes, arterial blood gases (ABG) and mean pulmonary artery pressure (PAP), before (T0-T1) and during (T1-T2) long-term oxygen therapy (LTO). LTO was initiated at T1 on usual criteria (PaO2 persistently less than or equal to 55 mm Hg) and was given during greater than or equal to 16 h/day. The T0-T1 period ranged from 12 to 186 months (mean 53 +/- 41 months) and the T1-T2 period from 12 to 120 months (mean 44 +/- 30 months). There was a significant worsening of the obstructive pattern (FEV1 decreasing from 1,084 +/- 326 to 879 +/- 318 ml, p less than 0.005) and of ABG (PaO2 decreasing from 58.2 +/- 9.2 to 51.6 +/- 6.5 mm Hg, p less than 0.01) before the onset of LTO, whereas there was a rather good stability of ABG during LTO and the changes in pulmonary volumes were modest and statistically nonsignificant (FEV1 decreased from 879 +/- 318 to 809 +/- 247 ml). PAP tended to increase from T0 to T1 and to decrease from T1 to T2, but these changes only reached the level of statistical significance when they were expressed as changes per year (+1.0 +/- 2.7 vs. -1.3 +/- 4.5 mm Hg, p less than 0.05). The evolution of physiological variables was nearly identical in subgroups of patients who had died (n = 13) or were still alive (n = 11) at the time of data collection (T3) and this held particularly true for PAP.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1991
- Full Text
- View/download PDF
32. Pulmonary hypertension, hypoxemia, and hypercapnia in obstructive sleep apnea patients.
- Author
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Krieger J, Sforza E, Apprill M, Lampert E, Weitzenblum E, and Ratomaharo J
- Subjects
- Cardiac Catheterization, Female, Humans, Male, Middle Aged, Monitoring, Physiologic, Prospective Studies, Respiratory Function Tests, Sleep Apnea Syndromes diagnosis, Hypercapnia complications, Hypertension, Pulmonary complications, Hypoxia complications, Sleep Apnea Syndromes complications
- Abstract
To define the parameters of respiratory insufficiency in OSA, 114 consecutive patients (108 men, six women) were prospectively studied. In addition to standard polysomnography, they underwent pulmonary function tests, right heart catheterization, and ventilatory response tests to hypercapnia. Nineteen patients (19 percent) had a resting PAP greater than or equal to 20 mm Hg. Multiple regression analysis showed that FEV1 and PaO2 (both with a negative coefficient) and PaCO2 (with a positive coefficient) significantly contributed to PAP. Thirteen patients (12 percent) had a PaCO2 greater than or equal to 45 mm Hg. A multiple regression analysis showed that FEV1 and the minute ventilation at PETCO2 = 60 mm Hg (both with a negative coefficient) and the cumulative apnea duration (with a positive coefficient) significantly contributed to PaCO2. Thirty-seven patients (33 percent) had a PaO2 less than or equal to 65 mm Hg. A multiple regression analysis showed that FEV1 (with a positive coefficient) and the hypopnea + apnea index (with a negative coefficient) significantly contributed to PaO2. These data confirm that impaired daytime pulmonary function (diffuse airway obstruction) contributes to the development of daytime pulmonary hypertension, hypoxemia, and hypercapnia in OSA patients. They show that the amount of sleep-related breathing disorders also plays a significant role.
- Published
- 1989
- Full Text
- View/download PDF
33. Daytime pulmonary hypertension in patients with obstructive sleep apnea syndrome.
- Author
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Weitzenblum E, Krieger J, Apprill M, Vallée E, Ehrhart M, Ratomaharo J, Oswald M, and Kurtz D
- Subjects
- Adult, Aged, Blood Pressure, Carbon Dioxide blood, Female, Humans, Hypertension, Pulmonary blood, Hypertension, Pulmonary physiopathology, Lung Volume Measurements, Male, Middle Aged, Oxygen blood, Pulmonary Wedge Pressure, Sleep Apnea Syndromes blood, Sleep Apnea Syndromes physiopathology, Hypertension, Pulmonary etiology, Sleep Apnea Syndromes complications
- Abstract
The frequency of daytime pulmonary hypertension (PH) in patients with obstructive sleep apnea syndrome (OSAS) has not been well established and its mechanisms are still under debate. We have thus performed right heart catheterization, in addition to standard spirography and arterial blood gas measurements, in a series of 46 consecutive patients in whom OSAS was firmly diagnosed by whole-night polysomnography. Only 9 of the 46 patients (20%) had PH defined by a mean resting pulmonary arterial pressure (Ppa) greater than or equal to 20 mm Hg. Among the patients without resting PH, 14 had exercising PH (defined by a Ppa greater than 30 mm Hg during 40-watt, steady-state exercise). Patients with resting PH differed from the others by a lower daytime PaO2 (60.8 +/- 7.6 versus 76.2 +/- 9.4 mm Hg; p less than 0.001), a higher daytime PaCO2 (44.6 +/- 4.2 versus 38.0 +/- 4.0 mm Hg; p less than 0.001), and lower VC and FEV1 (p less than 0.001). There was no difference between the 2 groups with regard to apnea index (62 +/- 34 versus 65 +/- 40) or the lowest sleep SaO2 (59 +/- 21 versus 66 +/- 18%) or the time spent in apnea. For the group as a whole, there was a good correlation between Ppa and daytime PaO2 (r = -0.61; p less than 0.001), PaCO2 (r = 0.55; p less than 0.001), and FEV1 (r = -0.52; p less than 0.001), but there was no significant correlation between Ppa and the apnea index, the lowest sleep SaO2, or the time spent in apnea.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1988
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