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Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers into clusters, overlooking the important functional signals present along the fiber tracts. There is increasing evidence that neural activity in the WM can be measured using functional MRI (fMRI), offering potentially valuable multimodal information for fiber clustering. In this paper, we develop a novel deep learning fiber clustering framework, namely Deep Multi-view Fiber Clustering (DMVFC), that uses joint dMRI and fMRI data to enable functionally consistent WM parcellation. DMVFC can effectively integrate the geometric characteristics of the WM fibers with the fMRI BOLD signals along the fiber tracts. It includes two major components: 1) a multi-view pretraining module to compute embedding features from fiber geometric information and functional signals separately, and 2) a collaborative fine-tuning module to simultaneously refine the two kinds of embeddings. In the experiments, we compare DMVFC with two state-of-the-art fiber clustering methods and demonstrate superior performance in achieving functionally meaningful and consistent WM parcellation results., Comment: 5 pages, 3 figures

Brain imaging studies have demonstrated that diffusion MRI tractography geometric shape descriptors can inform the study of the brain's white matter pathways and their relationship to brain function. In this work, we investigate the possibility of utilizing a deep learning model to compute shape measures of the brain's white matter connections. We introduce a novel framework, TractShapeNet, that leverages a point cloud representation of tractography to compute five shape measures: length, span, volume, total surface area, and irregularity. We assess the performance of the method on a large dataset including 1065 healthy young adults. Experiments for shape measure computation demonstrate that our proposed TractShapeNet outperforms other point cloud-based neural network models in both the Pearson correlation coefficient and normalized error metrics. We compare the inference runtime results with the conventional shape computation tool DSI-Studio. Our results demonstrate that a deep learning approach enables faster and more efficient shape measure computation. We also conduct experiments on two downstream language cognition prediction tasks, showing that shape measures from TractShapeNet perform similarly to those computed by DSI-Studio. Our code will be available at: https://github.com/SlicerDMRI/TractShapeNet., Comment: 10 pages, 2 figures, 4 tables. This work has been submitted to the IEEE for possible publication

We consider the fundamental problem of fairly allocating a set of indivisible items among agents having valuations that are represented by a multi-graph -- here, agents appear as the vertices and items as the edges between them and each vertex (agent) only values the set of its incident edges (items). The goal is to find a fair, i.e., envy-free up to any item (EFX) allocation. This model has recently been introduced by Christodoulou et al. (EC'23) where they show that EFX allocations always exist on simple graphs for monotone valuations, i.e., where any two agents can share at most one edge (item). A natural question arises as to what happens when we go beyond simple graphs and study various classes of multi-graphs? We answer the above question affirmatively for the valuation class of bipartite multi-graphs and multi-cycles. Our main positive result is that EFX allocations on bipartite multi-graphs (and multi-cycles) always exist and can be computed in polynomial time for additive valuations. We, therefore, push the frontiers of our understanding of EFX allocations and expand the scenarios where they are known to exist for an arbitrary number of agents. Next, we study EFX orientations (i.e., allocations where every item is allocated to one of its two endpoint agents) and give a complete picture of when they exist for bipartite multi-graphs dependent on two parameters -- the number of edges shared between any two agents and the diameter of the graph. Finally, we prove that it is NP-complete to determine whether a given fair division instance on a bipartite multi-graph admits an EFX orientation.

The shape of the brain's white matter connections is relatively unexplored in diffusion MRI tractography analysis. While it is known that tract shape varies in populations and across the human lifespan, it is unknown if the variability in dMRI tractography-derived shape may relate to the brain's functional variability across individuals. This work explores the potential of leveraging tractography fiber cluster shape measures to predict subject-specific cognitive performance. We implement machine learning models to predict individual cognitive performance scores. We study a large-scale database from the HCP-YA study. We apply an atlas-based fiber cluster parcellation to the dMRI tractography of each individual. We compute 15 shape, microstructure, and connectivity features for each fiber cluster. Using these features as input, we train a total of 210 models to predict 7 different NIH Toolbox cognitive performance assessments. We apply an explainable AI technique, SHAP, to assess the importance of each fiber cluster for prediction. Our results demonstrate that shape measures are predictive of individual cognitive performance. The studied shape measures, such as irregularity, diameter, total surface area, volume, and branch volume, are as effective for prediction as microstructure and connectivity measures. The overall best-performing feature is a shape feature, irregularity, which describes how different a cluster's shape is from an idealized cylinder. Further interpretation using SHAP values suggest that fiber clusters with features highly predictive of cognitive ability are widespread throughout the brain, including fiber clusters from the superficial association, deep association, cerebellar, striatal, and projection pathways. This study demonstrates the strong potential of shape descriptors to enhance the study of the brain's white matter and its relationship to cognitive function.

We study the classic problem of fairly dividing a set of indivisible items among a set of agents and consider the popular fairness notion of envy-freeness up to one item (EF1). While in reality, the set of agents and items may vary, previous works have studied static settings, where no change can occur in the system. We initiate and develop a formal model to understand fair division under the variable input setting: here, there is an EF1 allocation that gets disrupted because of the loss/deletion of an item, or the arrival of a new agent, resulting in a near-EF1 allocation. The objective is to perform a sequence of transfers of items between agents to regain EF1 fairness by traversing only via near-EF1 allocations. We refer to this as the EF1-Restoration problem. In this work, we present algorithms for the above problem when agents have identical monotone valuations, and items are either all goods or all chores. Both of these algorithms achieve an optimal number of transfers (at most $m/n$, where $m$ and $n$ are the number of items and agents respectively) for identical additive valuations. Next, we consider a valuation class with graphical structure, introduced by Christodoulou et al. (EC'23), where each item is valued by at most two agents, and hence can be seen as an edge between these two agents in a graph. Here, we consider EF1 orientations on (multi)graphs - allocations in which each item is allocated to an agent who values it. While considering EF1 orientations on multi-graphs with additive binary valuations, we present an optimal algorithm for the EF1-Restoration problem. Finally, for monotone binary valuations, we show that the problem of deciding whether EF1-Restoration is possible is PSPACE-complete.

Neurons in the brain are spatially organized such that neighbors on tissue often exhibit similar response profiles. In the human language system, experimental studies have observed clusters for syntactic and semantic categories, but the mechanisms underlying this functional organization remain unclear. Here, building on work from the vision literature, we develop TopoLM, a transformer language model with an explicit two-dimensional spatial representation of model units. By combining a next-token prediction objective with a spatial smoothness loss, representations in this model assemble into clusters that correspond to semantically interpretable groupings of text and closely match the functional organization in the brain's language system. TopoLM successfully predicts the emergence of the spatio-functional organization of a cortical language system as well as the organization of functional clusters selective for fine-grained linguistic features empirically observed in human cortex. Our results suggest that the functional organization of the human language system is driven by a unified spatial objective, and provide a functionally and spatially aligned model of language processing in the brain.

Electrified Medium Scale Traveling Ionospheric Disturbances (EMSTIDs) is one of the prominent plasma structures that affect the propagation of high frequency radio waves. Overall, seasonal variation and propagation characteristics of the EMSTIDs are widely reported in literature. However, the effects of substorms on the formation and dissipation of the EMSTIDs are not well explored. In the present study, on a moderately geomagnetically active night of 26 October 2019 (Ap=24), the airglow imager over Hanle (32.7{\deg}N, 78.9{\deg}E; Mlat. ~24.1{\deg}N), India recorded the evolution and decay of an EMSTID in the O(1D) 630.0 nm airglow images in between 13.3 UT and 15.8 UT. In addition, during the same time, a steep rise and fall of the virtual base height of the ionospheric F-layer were also recorded by a nearby digisonde over New Delhi (28.70{\deg}N, 77.10{\deg}E; Mlat. ~20.2{\deg}N). The most important aspect of the event was the occurrence of the two consecutive substorms in between 13.3 UT and 15.8 UT. To the best of our knowledge, this is the first of its kind study where we report the role of interplanetary electric field (IEF) and substorm induced electric fields on the evolution and decay of the EMSTID. This study elicits effects of the externally imposed electric fields on the mid-latitude ionospheric plasma structures and provides insight into the complex coupling between auroral and low-mid latitude region.

We present a JT gravity setup coupled with $U(1)$ and $SU(2)$ Yang-Mills fields in two dimensions that reveals the onset of a small black hole to large black hole phase transition at finite chemical potential(s). We identify these black hole solutions as topological defects in the thermodynamic phase space and calculate the associated topological numbers following the standard procedure. We confirm the robustness of our model by estimating perturbative corrections to the bulk free energy at an arbitrary order in the Yang-Mills coupling. We also construct the Schwarzian for the boundary theory using the 2D gravitational action in the bulk and comment on the dual SYK like model where similar observations can be made., Comment: 16 pages, 3 figures

The Orientation Distribution Function (ODF) characterizes key brain microstructural properties and plays an important role in understanding brain structural connectivity. Recent works introduced Implicit Neural Representation (INR) based approaches to form a spatially aware continuous estimate of the ODF field and demonstrated promising results in key tasks of interest when compared to conventional discrete approaches. However, traditional INR methods face difficulties when scaling to large-scale images, such as modern ultra-high-resolution MRI scans, posing challenges in learning fine structures as well as inefficiencies in training and inference speed. In this work, we propose HashEnc, a grid-hash-encoding-based estimation of the ODF field and demonstrate its effectiveness in retaining structural and textural features. We show that HashEnc achieves a 10% enhancement in image quality while requiring 3x less computational resources than current methods. Our code can be found at https://github.com/MunzerDw/NODF-HashEnc., Comment: 16 pages, 8 figures, conference: Medical Image Computing and Computer-Assisted Intervention (MICCAI)

Purpose: To develop and evaluate a new pulse sequence for highly accelerated distortion-free diffusion MRI (dMRI) by inserting an additional echo without prolonging TR, when generalized slice dithered enhanced resolution (gSlider) radiofrequency encoding is used for volumetric acquisition. Methods: A phase-reversed interleaved multi-echo acquisition (PRIME) was developed for rapid, high-resolution, and distortion-free dMRI, which includes two echoes where the first echo is for target diffusion-weighted imaging (DWI) acquisition with high-resolution and the second echo is acquired with either 1) lower-resolution for high-fidelity field map estimation, or 2) matching resolution to enable efficient diffusion relaxometry acquisitions. The sequence was evaluated on in vivo data acquired from healthy volunteers on clinical and Connectome 2.0 scanners. Results: In vivo experiments demonstrated that 1) high in-plane acceleration (Rin-plane of 5-fold with 2D partial Fourier) was achieved using the high-fidelity field maps estimated from the second echo, which was made at a lower resolution/acceleration to increase its SNR while matching the effective echo spacing of the first readout, 2) high-resolution diffusion relaxometry parameters were estimated from dual-echo PRIME data using a white matter model of multi-TE spherical mean technique (MTE-SMT), and 3) high-fidelity mesoscale DWI at 550 um isotropic resolution could be obtained in vivo by capitalizing on the high-performance gradients of the Connectome 2.0 scanner. Conclusion: The proposed PRIME sequence enabled highly accelerated, high-resolution, and distortion-free dMRI using an additional echo without prolonging scan time when gSlider encoding is utilized., Comment: 12 figures, 1 table

In this study, we developed an Evidence-based Ensemble Neural Network, namely EVENet, for anatomical brain parcellation using diffusion MRI. The key innovation of EVENet is the design of an evidential deep learning framework to quantify predictive uncertainty at each voxel during a single inference. Using EVENet, we obtained accurate parcellation and uncertainty estimates across different datasets from healthy and clinical populations and with different imaging acquisitions. The overall network includes five parallel subnetworks, where each is dedicated to learning the FreeSurfer parcellation for a certain diffusion MRI parameter. An evidence-based ensemble methodology is then proposed to fuse the individual outputs. We perform experimental evaluations on large-scale datasets from multiple imaging sources, including high-quality diffusion MRI data from healthy adults and clinically diffusion MRI data from participants with various brain diseases (schizophrenia, bipolar disorder, attention-deficit/hyperactivity disorder, Parkinson's disease, cerebral small vessel disease, and neurosurgical patients with brain tumors). Compared to several state-of-the-art methods, our experimental results demonstrate highly improved parcellation accuracy across the multiple testing datasets despite the differences in dMRI acquisition protocols and health conditions. Furthermore, thanks to the uncertainty estimation, our EVENet approach demonstrates a good ability to detect abnormal brain regions in patients with lesions, enhancing the interpretability and reliability of the segmentation results., Comment: 15 pages, 5 figures

We study the problem of computing \emph{fair} divisions of a set of indivisible goods among agents with \emph{additive} valuations. For the past many decades, the literature has explored various notions of fairness, that can be primarily seen as either having \emph{envy-based} or \emph{share-based} lens. For the discrete setting of resource-allocation problems, \emph{envy-free up to any good} (EFX) and \emph{maximin share} (MMS) are widely considered as the flag-bearers of fairness notions in the above two categories, thereby capturing different aspects of fairness herein. Due to lack of existence results of these notions and the fact that a good approximation of EFX or MMS does not imply particularly strong guarantees of the other, it becomes important to understand the compatibility of EFX and MMS allocations with one another. In this work, we identify a novel way to simultaneously achieve MMS guarantees with EFX/EF1 notions of fairness, while beating the best known approximation factors [Chaudhury et al., 2021, Amanatidis et al., 2020]. Our main contribution is to constructively prove the existence of (i) a partial allocation that is both $2/3$-MMS and EFX, and (ii) a complete allocation that is both $2/3$-MMS and EF1. Our algorithms run in pseudo-polynomial time if the approximation factor for MMS is relaxed to $2/3-\varepsilon$ for any constant $\varepsilon > 0$ and in polynomial time if, in addition, the EFX (or EF1) guarantee is relaxed to $(1-\delta)$-EFX (or $(1-\delta)$-EF1) for any constant $\delta>0$. In particular, we improve from the best approximation factor known prior to our work, which computes partial allocations that are $1/2$-MMS and EFX in pseudo-polynomial time [Chaudhury et al., 2021].

In this work, we present a novel method for extensive multi-scale generative terrain modeling. At the core of our model is a cascade of superresolution diffusion models that can be combined to produce consistent images across multiple resolutions. Pairing this concept with a tiled generation method yields a scalable system that can generate thousands of square kilometers of realistic Earth surfaces at high resolution. We evaluate our method on a dataset collected from Bing Maps and show that it outperforms super-resolution baselines on the extreme super-resolution task of 1024x zoom. We also demonstrate its ability to create diverse and coherent scenes via an interactive gigapixel-scale generated map. Finally, we demonstrate how our system can be extended to enable novel content creation applications including controllable world generation and 3D scene generation.

Parcellation of white matter tractography provides anatomical features for disease prediction, anatomical tract segmentation, surgical brain mapping, and non-imaging phenotype classifications. However, parcellation does not always reach 100\% accuracy due to various factors, including inter-individual anatomical variability and the quality of neuroimaging scan data. The failure to identify parcels causes a problem of missing microstructure data values, which is especially challenging for downstream tasks that analyze large brain datasets. In this work, we propose a novel deep-learning model to impute tissue microstructure: the White Matter Geometry-guided Diffusion (WMG-Diff) model. Specifically, we first propose a deep score-based guided diffusion model to impute tissue microstructure for diffusion magnetic resonance imaging (dMRI) tractography fiber clusters. Second, we propose a white matter atlas geometric relationship-guided denoising function to guide the reverse denoising process at the subject-specific level. Third, we train and evaluate our model on a large dataset with 9342 subjects. Comprehensive experiments for tissue microstructure imputation and a downstream non-imaging phenotype prediction task demonstrate that our proposed WMG-Diff outperforms the compared state-of-the-art methods in both error and accuracy metrics. Our code will be available at: https://github.com/SlicerDMRI/WMG-Diff., Comment: This paper has been accepted for presentation at The 31st International Conference on Neural Information Processing (ICONIP 2024). 12 pages, 3 figures, 2 tables

Recent advancements in Machine Learning (ML) have substantially improved its predictive and computational abilities, offering promising opportunities for surrogate modeling in scientific applications. By accurately approximating complex functions with low computational cost, ML-based surrogates can accelerate scientific applications by replacing computationally intensive components with faster model inference. However, integrating ML models into these applications remains a significant challenge, hindering the widespread adoption of ML surrogates as an approximation technique in modern scientific computing. We propose an easy-to-use directive-based programming model that enables developers to seamlessly describe the use of ML models in scientific applications. The runtime support, as instructed by the programming model, performs data assimilation using the original algorithm and can replace the algorithm with model inference. Our evaluation across five benchmarks, testing over 5000 ML models, shows up to 83.6x speed improvements with minimal accuracy loss (as low as 0.01 RMSE)., Comment: 16 pages, 9 figures. Accepted at SC24

Parcellation of human cerebellar pathways is essential for advancing our understanding of the human brain. Existing diffusion MRI tractography parcellation methods have been successful in defining major cerebellar fibre tracts, while relying solely on fibre tract structure. However, each fibre tract may relay information related to multiple cognitive and motor functions of the cerebellum. Hence, it may be beneficial for parcellation to consider the potential importance of the fibre tracts for individual motor and cognitive functional performance measures. In this work, we propose a multimodal data-driven method for cerebellar pathway parcellation, which incorporates both measures of microstructure and connectivity, and measures of individual functional performance. Our method involves first training a multitask deep network to predict various cognitive and motor measures from a set of fibre tract structural features. The importance of each structural feature for predicting each functional measure is then computed, resulting in a set of structure-function saliency values that are clustered to parcellate cerebellar pathways. We refer to our method as Deep Multimodal Saliency Parcellation (DeepMSP), as it computes the saliency of structural measures for predicting cognitive and motor functional performance, with these saliencies being applied to the task of parcellation. Applying DeepMSP we found that it was feasible to identify multiple cerebellar pathway parcels with unique structure-function saliency patterns that were stable across training folds.

The relationship between brain connections and non-imaging phenotypes is increasingly studied using deep neural networks. However, the local and global properties of the brain's white matter networks are often overlooked in convolutional network design. We introduce TractGraphFormer, a hybrid Graph CNN-Transformer deep learning framework tailored for diffusion MRI tractography. This model leverages local anatomical characteristics and global feature dependencies of white matter structures. The Graph CNN module captures white matter geometry and grey matter connectivity to aggregate local features from anatomically similar white matter connections, while the Transformer module uses self-attention to enhance global information learning. Additionally, TractGraphFormer includes an attention module for interpreting predictive white matter connections. In sex prediction tests, TractGraphFormer shows strong performance in large datasets of children (n=9345) and young adults (n=1065). Overall, our approach suggests that widespread connections in the WM are predictive of the sex of an individual, and consistent predictive anatomical tracts are identified across the two datasets. The proposed approach highlights the potential of integrating local anatomical information and global feature dependencies to improve prediction performance in machine learning with diffusion MRI tractography., Comment: 23 pages, 4 figures

Everyday AI detection requires differentiating between people and AI in informal, online conversations. In many cases, people will not interact directly with AI systems but instead read conversations between AI systems and other people. We measured how well people and large language models can discriminate using two modified versions of the Turing test: inverted and displaced. GPT-3.5, GPT-4, and displaced human adjudicators judged whether an agent was human or AI on the basis of a Turing test transcript. We found that both AI and displaced human judges were less accurate than interactive interrogators, with below chance accuracy overall. Moreover, all three judged the best-performing GPT-4 witness to be human more often than human witnesses. This suggests that both humans and current LLMs struggle to distinguish between the two when they are not actively interrogating the person, underscoring an urgent need for more accurate tools to detect AI in conversations.

Serial dictatorship is a simple mechanism for coordinating agents in solving combinatorial optimization problems according to their preferences. The most representative such problem is one-sided matching, in which a set of n agents have values for a set of n items, and the objective is to compute a matching of the agents to the items of maximum total value (a.k.a., social welfare). Following the recent framework of Caragiannis and Rathi [10], we consider a model in which the agent-item values are not available upfront but become known by querying agent sequences. In particular, when the agents are asked to act in a sequence, they respond by picking their favorite item that has not been picked by agents who acted before and reveal their value for it. Can we compute an agent sequence that induces a social welfare-optimal matching? We answer this question affirmatively and present an algorithm that uses polynomial number (n^5) of queries. This solves the main open problem stated by Caragiannis and Rathi [CR23]. Our analysis uses a potential function argument that measures progress towards learning the underlying edge-weight information. Furthermore, the algorithm has a truthful implementation by adapting the paradigm of VCG payments.

Stochastic programming provides a natural framework for modeling sequential optimization problems under uncertainty; however, the efficient solution of large-scale multistage stochastic programs remains a challenge, especially in the presence of discrete decisions and nonlinearities. In this work, we consider multistage stochastic mixed-integer nonlinear programs (MINLPs) with discrete state variables, which exhibit a decomposable structure that allows its solution using a column generation approach. Following a Dantzig-Wolfe reformulation, we apply column generation such that each pricing subproblem is an MINLP of much smaller size, making it more amenable to global MINLP solvers. We further propose a method for generating additional columns that satisfy the nonanticipativity constraints, leading to significantly improved convergence and optimal or near-optimal solutions for many large-scale instances in a reasonable computation time. The effectiveness of the tailored column generation algorithm is demonstrated via computational case studies on a multistage blending problem and a problem involving the routing of mobile generators in a power distribution network., Comment: 31 pages, 10 figures

It is often noted that single query-item pair relevance training in search does not capture the customer intent. User intent can be better deduced from a series of engagements (Clicks, ATCs, Orders) in a given search session. We propose a novel method for vectorizing session context for capturing and utilizing context in retrieval and rerank. In the runtime, session embedding is an alternative to query embedding, saved and updated after each request in the session, it can be used for retrieval and ranking. We outline session embedding's solution to session-based intent understanding and its architecture, the background to this line of thought in search and recommendation, detail the methodologies implemented, and finally present the results of an implementation of session embedding for query product type classification. We demonstrate improvements over strategies ignoring session context in the runtime for user intent understanding., Comment: 5 pages, 1 Figure, 5 Tables, SIGIR 2024, LLM for Individuals, Groups, and Society

We study the fundamental problem of fairly dividing a set of indivisible items among agents with (general) monotone valuations. The notion of envy-freeness up to any item (EFX) is considered to be one of the most fascinating fairness concepts in this line of work. Unfortunately, despite significant efforts, existence of EFX allocations is a major open problem in fair division, thereby making the study of approximations and relaxations of EFX a natural line of research. Recently, Caragiannis et al. introduced a promising relaxation of EFX, called epistemic EFX (EEFX). We say an allocation to be EEFX if, for every agent, it is possible to shuffle the items in the remaining bundles so that she becomes "EFX-satisfied". Caragiannis et al. prove existence and polynomial-time computability of EEFX allocations for additive valuations. A natural question asks what happens when we consider valuations more general than additive? We address this important open question and answer it affirmatively by establishing the existence of EEFX allocations for an arbitrary number of agents with general monotone valuations. To the best of our knowledge, EEFX is the only known relaxation of EFX (beside EF1) to have such strong existential guarantees. Furthermore, we complement our existential result by proving computational and information-theoretic lower bounds. We prove that even for an arbitrary number of (more than one) agents with identical submodular valuations, it is PLS-hard to compute EEFX allocations and it requires exponentially-many value queries to do so.

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors such as variable dimensionalities (reflecting the unknown number of distinct white matter fiber populations in a voxel), low signal-to-noise ratios, and non-linear forward models. These challenges have led many existing methods to use biologically implausible simplified models to stabilize estimation, for instance, assuming shared microstructure across all fiber populations within a voxel. In this work, we introduce a novel sequential method for multi-fiber parameter inference that decomposes the task into a series of manageable subproblems. These subproblems are solved using deep neural networks tailored to problem-specific structure and symmetry, and trained via simulation. The resulting inference procedure is largely amortized, enabling scalable parameter estimation and uncertainty quantification across all model parameters. Simulation studies and real imaging data analysis using the Human Connectome Project (HCP) demonstrate the advantages of our method over standard alternatives. In the case of the standard model of diffusion, our results show that under HCP-like acquisition schemes, estimates for extra-cellular parallel diffusivity are highly uncertain, while those for the intra-cellular volume fraction can be estimated with relatively high precision.

The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool in assessing white matter (WM) connectivity and brain tissue microstructure across different populations. However, a comprehensive investigation into WM fiber tracts between Eastern and Western populations is challenged due to the lack of a cross-population WM atlas and the large site-specific variability of dMRI data. This study presents a dMRI tractography atlas, namely the East-West WM Atlas, for concurrent WM mapping between Eastern and Western populations and creates a large, harmonized dMRI dataset (n=306) based on the Human Connectome Project and the Chinese Human Connectome Project. The curated WM atlas, as well as subject-specific data including the harmonized dMRI data, the whole brain tractography data, and parcellated WM fiber tracts and their diffusion measures, are publicly released. This resource is a valuable addition to facilitating the exploration of brain commonalities and differences across diverse cultural backgrounds.

In the present thesis, we study various models of 2D dilaton gravity known as JT gravity coupled with non-trivial gauge interactions (for instance $SU(2)$ Yang-Mills, quartic interactions between $U(1)$ gauge fields and Modmax interactions etc.). In particular, we investigate the effects of the non-trivial gauge couplings on the thermal properties of black holes and wormholes in two dimensions and compute various physical observables like entropy, free energy, etc. Further, we examine the possibilities of the Hawking-Page transition and wormhole to black hole phase transition in two dimensions. In addition, we also study the transformation properties of boundary stress-energy tensor under the diffeomorphism and $U(1)$ gauge transformation and hence compute the central charge associated with the 1D boundary theory., Comment: 278 pages, 6 figures, Ph.D. Thesis

In general, nighttime thermospheric 557.7 nm emission over mid-latitudes is predominantly masked by significantly larger mesospheric component, and hence, F-region plasma structures are rarely observed in this emission. This paper reports the first rare simultaneous detection of F-region plasma depleted structure in O($^1$D) 630.0 nm and O($^1$S) 557.7 nm airglow images from Hanle, India, a mid-latitude station (32.7{\deg}N, 78.9{\deg}E; Mlat. ~24.1{\deg}N) on a geomagnetically quiet night (Ap=3) of 26 June 2021. This indicates significant enhancement of thermospheric 557.7 nm emission. Interestingly, thermospheric 557.7 nm emission was not significant on the following geomagnetically quiet night as MSTID bands were only observed in 630.0 nm images. We show that enhanced dissociative recombination caused by descent of F-layer peak over the observation region coupled with the significant increase of the electron density at thermospheric 557.7 nm emission altitude enabled the detection of the plasma depleted structure on 26 June 2021.

Shape plays an important role in computer graphics, offering informative features to convey an object's morphology and functionality. Shape analysis in brain imaging can help interpret structural and functionality correlations of the human brain. In this work, we investigate the shape of the brain's 3D white matter connections and its potential predictive relationship to human cognitive function. We reconstruct brain connections as sequences of 3D points using diffusion magnetic resonance imaging (dMRI) tractography. To describe each connection, we extract 12 shape descriptors in addition to traditional dMRI connectivity and tissue microstructure features. We introduce a novel framework, Shape--fused Fiber Cluster Transformer (SFFormer), that leverages a multi-head cross-attention feature fusion module to predict subject-specific language performance based on dMRI tractography. We assess the performance of the method on a large dataset including 1065 healthy young adults. The results demonstrate that both the transformer-based SFFormer model and its inter/intra feature fusion with shape, microstructure, and connectivity are informative, and together, they improve the prediction of subject-specific language performance scores. Overall, our results indicate that the shape of the brain's connections is predictive of human language function., Comment: This paper has been accepted for presentation at The 27th Intl. Conf. on Medical Image Computing and Computer Assisted Intervention (MICCAI 2024) Workshop on Computational Diffusion MRI (CDMRI). 11 pages, 2 figures

Solar transient events like flares can cause sudden changes in planetary plasma and neutral environment. Here, we present an investigation of the variability of the Martian atmospheric emissions viz. OI 130.4 nm, 135.6 nm, CO2+ ultraviolet doublet (UVD), and CO Cameron band (CB) in the less explored dayside near-terminator region during solar flare events. The two X8.2 and M6 class flares during September 2017 on Mars have been selected from existing catalogs. Using data from the imaging ultraviolet spectrograph (IUVS) aboard the MAVEN spacecraft, we examined limb radiance profiles. We observed a significant increase in radiance for major emissions around the peak with a more pronounced impact below the peak during flares compared to quiet time. During solar flares, for 130.4 nm and 135.6 nm emission, the maximum deviation in radiance beneath peak approaches to ~63% and ~123%, respectively. Whereas, for CO2+ UVD and CO CB, it is ~64% and ~50%, respectively. Additionally, we have presented an average scenario of dayside near-terminator (SZA~70-90{\deg}) and observed a notable trend of higher percentage deviation for atomic emissions compared to molecular emissions during flares. Further, our analysis depicts a higher percentage deviation during X8.2 compared to M6 class flare. This study underscores that during flares, higher photoelectron impact and irradiance flux drive the production processes, leading to enhanced emissions. The case studies emphasize, for the first time, the significant influence of flares on the Martian dayside near-terminator region, advancing our deeper understanding the impact of varying solar flare intensities to the planetary atmosphere.

Large datasets often contain multiple distinct feature sets, or views, that offer complementary information that can be exploited by multi-view learning methods to improve results. We investigate anatomical multi-view data, where each brain anatomical structure is described with multiple feature sets. In particular, we focus on sets of white matter microstructure and connectivity features from diffusion MRI, as well as sets of gray matter area and thickness features from structural MRI. We investigate machine learning methodology that applies multi-view approaches to improve the prediction of non-imaging phenotypes, including demographics (age), motor (strength), and cognition (picture vocabulary). We present an explainable multi-view network (EMV-Net) that can use different anatomical views to improve prediction performance. In this network, each individual anatomical view is processed by a view-specific feature extractor and the extracted information from each view is fused using a learnable weight. This is followed by a wavelet transform-based module to obtain complementary information across views which is then applied to calibrate the view-specific information. Additionally, the calibrator produces an attention-based calibration score to indicate anatomical structures' importance for interpretation., Comment: 2023 The Medical Image Computing and Computer Assisted Intervention Society workshop

Sequential recommenders are crucial to the success of online applications, \eg e-commerce, video streaming, and social media. While model architectures continue to improve, for every new application domain, we still have to train a new model from scratch for high quality recommendations. On the other hand, pre-trained language and vision models have shown great success in zero-shot or few-shot adaptation to new application domains. Inspired by the success of pre-trained models in peer AI fields, we propose a novel pre-trained sequential recommendation framework: PrepRec. We learn universal item representations by modeling item popularity dynamics. Through extensive experiments on five real-world datasets, we show that PrepRec, without any auxiliary information, can not only zero-shot transfer to a new domain, but achieve competitive performance compared to state-of-the-art sequential recommender models with only a fraction of the model size. In addition, with a simple post-hoc interpolation, PrepRec can improve the performance of existing sequential recommenders on average by 13.8\% in Recall@10 and 29.5% in NDCG@10. We provide an anonymized implementation of PrepRec at https://anonymous.4open.science/r/PrepRec--2F60/

In the osmotic power generation field, reaching the industrial benchmark has been challenging because of the need for capillaries close to the sizes of ions and molecules. Here, we fabricated well-controlled 'along-the-capillary' membranes of Na-vermiculite with a capillary size of ~5 Angstrom. They exhibit 1600 times enhanced conductivity compared to commonly studied 'across-the-capillary' membranes. Interestingly, they show a very high cation selectivity of 0.83 for NaCl solutions, which resulted in large power densities of 9.6 W.m^-2 and 12.2 W.m^-2 at concentration gradients of 50 and 1000, respectively, at 296 K, for an unusually large membrane length of 100 micron. The power density shows an exponential increase with temperature, reaching 65.1 W.m-2 for a concentration gradient of 50 at 333 K. This markedly differs from the classical behavior and indicates the role of ion (de)hydration in enhancing power density, opening new possibilities for exploiting such membranes for energy harvesting applications., Comment: 34 pages, 4 main figures