45 results on '"Raquel Afonso Caserta Eid"'
Search Results
2. Ringing a bell in healthcare: harnessing benefits, overcoming implementation challenges, and bridging knowledge gaps of Closed-Loop Oxygen Control systems (CLOCs)
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Caroline Gomes Mól, Aléxia Gabriela da Silva Vieira, Raquel Afonso Caserta Eid, Ary Serpa Neto, Marcus J. Schultz, and Ricardo Kenji Nawa
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Medicine - Published
- 2024
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3. Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study
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Thiago Domingos Corrêa, Thais Dias Midega, Ricardo Luiz Cordioli, Carmen Silvia Valente Barbas, Roberto Rabello Filho, Bruno Caldin da Silva, Moacyr Silva Júnior, Ricardo Kenji Nawa, Fabrício Rodrigues Torres de Carvalho, Gustavo Faissol Janot de Matos, Neide Marcela Lucinio, Rodrigo Dias Rodrigues, Raquel Afonso Caserta Eid, Bruno de Arruda Bravim, Adriano José Pereira, Bento Fortunato Cardoso dos Santos, João Renato Rebello Pinho, Andreia Pardini, Vanessa Damazio Teich, Claudia Regina Laselva, Miguel Cendoroglo Neto, Sidney Klajner, and Leonardo José Rolim Ferraz
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Coronavirus infections ,COVID-19 ,SARS-CoV-2 ,Respiration, artificial ,Noninvasive ventilation ,Extracorporeal membrane oxygenation ,Critical care outcomes ,Mortality ,Intensive care units ,Medicine - Abstract
ABSTRACT Objective To describe and compare the clinical characteristics and outcomes of patients admitted to intensive care units during the first and second waves of the COVID-19 pandemic. Methods In this retrospective single-center cohort study, data were retrieved from the Epimed Monitor System; all adult patients admitted to the intensive care unit between March 4, 2020, and October 1, 2021, were included in the study. We compared the clinical characteristics and outcomes of patients admitted to the intensive care unit of a quaternary private hospital in São Paulo, Brazil, during the first (May 1, 2020, to August 31, 2020) and second (March 1, 2021, to June 30, 2021) waves of the COVID-19 pandemic. Results In total, 1,427 patients with COVID-19 were admitted to the intensive care unit during the first (421 patients) and second (1,006 patients) waves. Compared with the first wave group [median (IQR)], the second wave group was younger [57 (46-70) versus 67 (52-80) years; p
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- 2023
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4. Rehabilitation approach after 2 years of the COVID-19 pandemic: lessons to be learned
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Ricardo Kenji Nawa, Suelen Elaine Uhlig, Carla Luciana Batista, Raquel Afonso Caserta Eid, and Caroline Gomes Mól
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Medicine - Published
- 2023
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5. Analysis of mobility level of COVID-19 patients undergoing mechanical ventilation support: A single center, retrospective cohort study.
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Ricardo Kenji Nawa, Ary Serpa Neto, Ana Carolina Lazarin, Ana Kelen da Silva, Camila Nascimento, Thais Dias Midega, Raquel Afonso Caserta Eid, Thiago Domingos Corrêa, and Karina Tavares Timenetsky
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Medicine ,Science - Abstract
BackgroundSevere coronavirus disease 2019 (COVID-19) patients frequently require mechanical ventilation (MV) and undergo prolonged periods of bed rest with restriction of activities during the intensive care unit (ICU) stay. Our aim was to address the degree of mobilization in critically ill patients with COVID-19 undergoing to MV support.MethodsRetrospective single-center cohort study. We analyzed patients' mobility level, through the Perme ICU Mobility Score (Perme Score) of COVID-19 patients admitted to the ICU. The Perme Mobility Index (PMI) was calculated [PMI = ΔPerme Score (ICU discharge-ICU admission)/ICU length of stay], and patients were categorized as "improved" (PMI > 0) or "not improved" (PMI ≤ 0). Comparisons were performed with stratification according to the use of MV support.ResultsFrom February 2020, to February 2021, 1,297 patients with COVID-19 were admitted to the ICU and assessed for eligibility. Out of those, 949 patients were included in the study [524 (55.2%) were classified as "improved" and 425 (44.8%) as "not improved"], and 396 (41.7%) received MV during ICU stay. The overall rate of patients out of bed and able to walk ≥ 30 meters at ICU discharge were, respectively, 526 (63.3%) and 170 (20.5%). After adjusting for confounders, independent predictors of improvement of mobility level were frailty (OR: 0.52; 95% CI: 0.29-0.94; p = 0.03); SAPS III Score (OR: 0.75; 95% CI: 0.57-0.99; p = 0.04); SOFA Score (OR: 0.58; 95% CI: 0.43-0.78; p < 0.001); use of MV after the first hour of ICU admission (OR: 0.41; 95% CI: 0.17-0.99; p = 0.04); tracheostomy (OR: 0.54; 95% CI: 0.30-0.95; p = 0.03); use of extracorporeal membrane oxygenation (OR: 0.21; 95% CI: 0.05-0.8; p = 0.03); neuromuscular blockade (OR: 0.53; 95% CI: 0.3-0.95; p = 0.03); a higher Perme Score at admission (OR: 0.35; 95% CI: 0.28-0.43; p < 0.001); palliative care (OR: 0.05; 95% CI: 0.01-0.16; p < 0.001); and a longer ICU stay (OR: 0.79; 95% CI: 0.61-0.97; p = 0.04) were associated with a lower chance of mobility improvement, while non-invasive ventilation within the first hour of ICU admission and after the first hour of ICU admission (OR: 2.45; 95% CI: 1.59-3.81; p < 0.001) and (OR: 2.25; 95% CI: 1.56-3.26; p < 0.001), respectively; and vasopressor use (OR: 2.39; 95% CI: 1.07-5.5; p = 0.03) were associated with a higher chance of mobility improvement.ConclusionThe use of MV reduced mobility status in less than half of critically ill COVID-19 patients.
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- 2022
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6. Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study
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Thiago Domingos Corrêa, Thais Dias Midega, Karina Tavares Timenetsky, Ricardo Luiz Cordioli, Carmen Silvia Valente Barbas, Moacyr Silva Júnior, Bruno de Arruda Bravim, Bruno Caldin Silva, Gustavo Faissol Janot de Matos, Ricardo Kenji Nawa, Fabrício Rodrigues Torres de Carvalho, Verônica Neves Fialho Queiroz, Roberto Rabello Filho, Felipe Maia de Toledo Piza, Adriano José Pereira, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, Bento Fortunato Cardoso dos Santos, Andreia Pardini, Vanessa Damázio Teich, Claudia Regina Laselva, Miguel Cendoroglo Neto, Sidney Klajner, and Leonardo José Rolim Ferraz
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Coronavirus ,COVID-19 ,Coronavirus infections ,SARS-CoV-2 ,Betacoronavirus ,Intensive care units ,Respiration, artificial ,Noninvasive ventilation ,Extracorporeal membrane oxygenation ,Critical care outcomes ,Mortality ,Medicine - Abstract
ABSTRACT Objective: To describe clinical characteristics, resource use, outcomes, and to identify predictors of in-hospital mortality of patients with COVID-19 admitted to the intensive care unit. Methods: Retrospective single-center cohort study conducted at a private hospital in São Paulo (SP), Brazil. All consecutive adult (≥18 years) patients admitted to the intensive care unit, between March 4, 2020 and February 28, 2021 were included in this study. Patients were categorized between survivors and non-survivors according to hospital discharge. Results: During the study period, 1,296 patients [median (interquartile range) age: 66 (53-77) years] with COVID-19 were admitted to the intensive care unit. Out of those, 170 (13.6%) died at hospital (non-survivors) and 1,078 (86.4%) were discharged (survivors). Compared to survivors, non-survivors were older [80 (70-88) versus 63 (50-74) years; p
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- 2021
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7. The Perme Mobility Index: A new concept to assess mobility level in patients with coronavirus (COVID-19) infection.
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Karina Tavares Timenetsky, Ary Serpa Neto, Ana Carolina Lazarin, Andreia Pardini, Carla Regina Sousa Moreira, Thiago Domingos Corrêa, Raquel Afonso Caserta Eid, and Ricardo Kenji Nawa
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Medicine ,Science - Abstract
IntroductionThe Coronavirus Disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. Data on the mobility level of patients with COVID-19 in the intensive care unit (ICU) are needed.ObjectiveTo describe the mobility level of patients with COVID-19 admitted to the ICU and to address factors associated with mobility level at the time of ICU discharge.MethodsSingle center, retrospective cohort study. Consecutive patients admitted to the ICU with confirmed COVID-19 infection were analyzed. The mobility status was assessed by the Perme Score at admission and discharge from ICU with higher scores indicating higher mobility level. The Perme Mobility Index (PMI) was calculated [PMI = ΔPerme Score (ICU discharge-ICU admission)/ICU length of stay]. Based on the PMI, patients were divided into two groups: "Improved" (PMI > 0) and "Not improved" (PMI ≤ 0).ResultsA total of 136 patients were included in this analysis. The hospital mortality rate was 16.2%. The Perme Score improved significantly when comparing ICU discharge with ICU admission [20.0 (7-28) points versus 7.0 (0-16) points; P < 0.001]. A total of 88 patients (64.7%) improved their mobility level during ICU stay, and the median PMI of these patients was 1.5 (0.6-3.4). Patients in the improved group had a lower duration of mechanical ventilation [10 (5-14) days versus 15 (8-24) days; P = 0.021], lower hospital length of stay [25 (12-37) days versus 30 (11-48) days; P < 0.001], and lower ICU and hospital mortality rate. Independent predictors for mobility level were lower age, lower Charlson Comorbidity Index, and not having received renal replacement therapy.ConclusionPatients' mobility level was low at ICU admission; however, most patients improved their mobility level during ICU stay. Risk factors associated with the mobility level were age, comorbidities, and use of renal replacement therapy.
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- 2021
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8. Comment to: Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
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Thiago Domingos Corrêa, Gustavo Faissol Janot de Matos, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Alejandra del Pilar Gallardo Garrido, Murillo Santucci Cesar de Assuncao, Carmen Silvia Valente Barbas, Karina Tavares Timenetsky, Roseny dos Reis Rodrigues, Hélio Penna Guimarães, Roberto Rabello Filho, Frederico Polito Lomar, Farah Christina de La Cruz Scarin, Carla Luciana Batista, Adriano José Pereira, João Carlos de Campos Guerra, Bárbara Vieira Carneiro, Ricardo Kenji Nawa, Rodrigo Martins Brandão, Antônio Eduardo Pereira Pesaro, Moacyr Silva Júnior, Fabricio Rodrigues Torres de Carvalho, Cilene Saghabi de Medeiros Silva, Ana Claudia Ferraz de Almeida, Marcelo Franken, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, and Leonardo José Rolim Ferraz
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Medicine - Published
- 2020
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9. Adaptation to different noninvasive ventilation masks in critically ill patients
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Renata Matos da Silva, Karina Tavares Timenetsky, Renata Cristina Miranda Neves, Liane Hirano Shigemichi, Sandra Sayuri Kanda, Carla Maekawa, Eliezer Silva, and Raquel Afonso Caserta Eid
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Ventilacao com pressao positiva intermitente ,Mascaras ,Insuficiencia respiratoria ,Diseases of the respiratory system ,RC705-779 - Abstract
OBJECTIVE: To identify which noninvasive ventilation (NIV) masks are most commonly used and the problems related to the adaptation to such masks in critically ill patients admitted to a hospital in the city of São Paulo, Brazil. METHODS: An observational study involving patients ≥ 18 years of age admitted to intensive care units and submitted to NIV. The reason for NIV use, type of mask, NIV regimen, adaptation to the mask, and reasons for non-adaptation to the mask were investigated. RESULTS: We evaluated 245 patients, with a median age of 82 years. Acute respiratory failure was the most common reason for NIV use (in 71.3%). Total face masks were the most commonly used (in 74.7%), followed by full face masks and near-total face masks (in 24.5% and 0.8%, respectively). Intermittent NIV was used in 82.4% of the patients. Adequate adaptation to the mask was found in 76% of the patients. Masks had to be replaced by another type of mask in 24% of the patients. Adequate adaptation to total face masks and full face masks was found in 75.5% and 80.0% of the patients, respectively. Non-adaptation occurred in the 2 patients using near-total facial masks. The most common reason for non-adaptation was the shape of the face, in 30.5% of the patients. CONCLUSIONS: In our sample, acute respiratory failure was the most common reason for NIV use, and total face masks were the most commonly used. The most common reason for non-adaptation to the mask was the shape of the face, which was resolved by changing the type of mask employed.
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- 2013
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10. Design of an instrument to measure the quality of care in Physical Therapy
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Leny Vieira Cavalheiro, Raquel Afonso Caserta Eid, Claudia Talerman, Cristiane do Prado, Fátima Cristina Martorano Gobbi, and Paola Bruno de Araujo Andreoli
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Qualidade da assistência à saúde ,Medidas, métodos e teorias ,Fisioterapia ,Medicine - Abstract
ABSTRACT Objective: To design an instrument composed of domains that would demonstrate physical therapy activities and generate a consistent index to represent the quality of care in physical therapy. Methods: The methodology Lean Six Sigma was used to design the tool. The discussion involved seven different management groups staff. By means of brainstorming and Cause & Effect Matrix, we set up the process map. Results: Five requirements composed the quality of care index in physical therapy, after application of the tool called Cause & Effect Matrix. The following requirements were assessed: physical therapist performance, care outcome indicator, adherence to physical therapy protocols, measure whether the prognosis and treatment outcome was achieved and Infrastructure. Conclusion: The proposed design allowed evaluating several items related to physical therapy service, enabling customization, reproducibility and benchmarking with other organizations. For management, this index provides the opportunity to identify areas for improvement and the strengths of the team and process of physical therapy care.
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11. Impact of respiratory therapy in vital capacity and functionality of patients undergoing abdominal surgery
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Shanlley Cristina da Silva Fernandes, Rafaella Souza dos Santos, Erica Albanez Giovanetti, Corinne Taniguchi, Cilene Saghabi de Medeiros Silva, Raquel Afonso Caserta Eid, Karina Tavares Timenetsky, and Denise Carnieli-Cazati
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Breathing exercises ,Respiratory function tests ,Respiratory muscles ,Vital capacity ,Medicine - Abstract
ABSTRACT Objective To evaluate the vital capacity after two chest therapy techniques in patients undergoing abdominal surgical. Methods A prospective randomized study carried out with patients admitted to the Intensive Care Unit after abdominal surgery. We checked vital capacity, muscular strength using the Medical Research Council scale, and functionality with the Functional Independence Measure the first time the patient was breathing spontaneously (D1), and also upon discharge from the Intensive Care Unit (Ddis). Between D1 and Ddis, respiratory therapy was carried out according to the randomized group. Results We included 38 patients, 20 randomized to Positive Intermittent Pressure Group and 18 to Volumetric Incentive Spirometer Group. There was no significant gain related to vital capacity of D1 and Ddis of Positive Intermittent Pressure Group (mean 1,410mL±547.2 versus 1,809mL±692.3; p=0.979), as in the Volumetric Incentive Spirometer Group (1,408.3mL±419.1 versus 1,838.8mL±621.3; p=0.889). We observed a significant improvement in vital capacity in D1 (p
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12. Bronchial hygiene techniques in patients on mechanical ventilation: what are used and why?
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Isabela Naiara Evangelista Matilde, Raquel Afonso Caserta Eid, Andréia Ferreira Nunes, Alexandre Ricardo Pepe Ambrozin, Renata Henn Moura, Denise Carnieli-Cazati, and Karina Tavares Timenetsky
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Respiração artificial ,Modalidades de fisioterapia ,Serviço hospitalar de fisioterapia ,Medicina baseada em evidências ,Medicine - Abstract
ABSTRACT Objective To analyze and describe the maneuvers most commonly used in clinical practice by physical therapists and the reasons for choosing them. Methods A prospective multicenter study using a questionnaire. The sample consisted of physical therapists from five hospitals (three private hospitals, a teaching hospital and a public hospital). Results A total of 185 questionnaires were filled in. Most professionals had graduated 6 to 10 years before and over had over 10 years of intensive care unit experience. The most often used maneuvers were vibrocompression, hyperinflation, postural drainage, tracheal suction and motor mobilization. The most frequent reason for choosing these maneuvers was “I notice they are more efficient in clinical practice.” Conclusion Physical therapy is mostly based on individual experience acquired in the clinical practice, and not on the scientific literature.
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13. Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
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Thiago Domingos Corrêa, Gustavo Faissol Janot de Matos, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Alejandra del Pilar Gallardo Garrido, Murillo Santucci Cesar de Assuncao, Carmen Silvia Valente Barbas, Karina Tavares Timenetsky, Roseny dos Reis Rodrigues, Hélio Penna Guimarães, Roberto Rabello Filho, Frederico Polito Lomar, Farah Christina de La Cruz Scarin, Carla Luciana Batista, Adriano José Pereira, João Carlos de Campos Guerra, Bárbara Vieira Carneiro, Ricardo Kenji Nawa, Rodrigo Martins Brandão, Antônio Eduardo Pereira Pesaro, Moacyr Silva Júnior, Fabricio Rodrigues Torres de Carvalho, Cilene Saghabi de Medeiros Silva, Ana Claudia Ferraz de Almeida, Marcelo Franken, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, and Leonardo José Rolim Ferraz
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coronavirus ,covid-19 ,respiratory insufficiency ,respiratory distress syndrome, adult ,intensive care units ,Medicine - Abstract
ABSTRACT In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome. Subsequently, COVID-19 was attributed to a new betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Approximately 20% of patients diagnosed as COVID-19 develop severe forms of the disease, including acute hypoxemic respiratory failure, severe acute respiratory syndrome, acute respiratory distress syndrome and acute renal failure and require intensive care. There is no randomized controlled clinical trial addressing potential therapies for patients with confirmed COVID-19 infection at the time of publishing these treatment recommendations. Therefore, these recommendations are based predominantly on the opinion of experts (level C of recommendation).
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14. Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-COVID-19 conditions: a systematic review
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Aléxia Gabriela da Silva Vieira, Ana Carolina Pereira Nunes Pinto, Bianca Maria Schneider Pereira Garcia, Raquel Afonso Caserta Eid, Caroline Gomes Mól, and Ricardo Kenji Nawa
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Dyspnea ,Quality of Life ,COVID-19 ,Humans ,Physical Therapy, Sports Therapy and Rehabilitation ,Breathing Exercises ,Telerehabilitation - Abstract
How effective and safe is telerehabilitation for people with COVID-19 and post-COVID-19 conditions?Systematic review of randomised trials.People with COVID-19 and post-COVID-19 conditions.Any type of telerehabilitation.Satisfaction, quality of life, adverse events, adherence to telerehabilitation, dyspnoea, functional performance, readmissions, mortality, pulmonary function and level of independence.Database searches retrieved 2,962 records, of which six trials with 323 participants were included in the review. Breathing exercises delivered via telerehabilitation improved 6-minute walk distance (MD 101 m, 95% CI 61 to 141; two studies), 30-second sit-to-stand test performance (MD 2.2 repetitions, 95% CI 1.5 to 2.8; two studies), Multidimensional Dyspnoea-12 questionnaire scores (MD -6, 95% CI -7 to -5; two studies) and perceived effort on the 0-to-10 Borg scale (MD -2.8, 95% CI -3.3 to -2.3; two studies), with low certainty of evidence. Exercise delivered via telerehabilitation improved 6-minute walk distance (MD 62 m, 95% CI 42 to 82, four studies), 30-second sit-to-stand test performance (MD 2.0 repetitions, 95% CI 1.3 to 2.7; two studies) and Multidimensional Dyspnoea-12 scores (MD -1.8, 95% CI -2.5 to -1.1; one study), with low certainty of evidence. Adverse events were almost all mild or moderate and occurred with similar frequency in the telerehabilitation group (median 0 per participant, IQR 0 to 2.75) as in the control group (median 0 per participant, IQR 0 to 2); Hodges-Lehmann median difference 0 (95% CI 0 to 0), with low certainty of evidence.Telerehabilitation may improve functional capacity, dyspnoea, performance and physical components of quality of life and does not substantially increase adverse events.PROSPERO CRD42021271049.
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- 2021
15. Closed-loop oxygen control for patients with hypoxaemia during hospitalisation: a living systematic review and meta-analysis protocol
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Caroline Gomes Mol, Aléxia Gabriela da Silva Vieira, Bianca Maria Schneider Pereira Garcia, Emanuel dos Santos Pereira, Raquel Afonso Caserta Eid, Ana Carolina Pereira Nunes Pinto, and Ricardo Kenji Nawa
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General Medicine - Abstract
IntroductionOxygen is the most common drug used in critical care patients to correct episodes of hypoxaemia. The adoption of new technologies in clinical practice, such as closed-loop systems for an automatic oxygen titration, may improve outcomes and reduce the healthcare professionals’ workload at the bedside; however, certainty of the evidence regarding the safety and benefits still remains low. We aim to evaluate the effectiveness, efficacy and safety of the closed-loop oxygen control for patients with hypoxaemia during the hospitalisation period by conducting a systematic review and meta-analysis.Methods and analysisMEDLINE, CENTRAL, EMBASE, LILACS, CINAHL and LOVE evidence databases will be searched. Randomised controlled trials and cross-over studies investigating the PICO (Population, Intervention, Comparator and Outcome) framework will be included. The primary outcomes will be the time in the peripheral oxygen saturation target. Secondary outcomes will include time for oxygen weaning time; length of stay; costs; adverse events; mortality; healthcare professionals’ workload, and percentage of time with hypoxia and hyperoxia. Two reviewers will independently screen and extract data and perform quality assessment of included studies. The Cochrane risk of bias tool will be used to assess risk of bias. The RevMan V.5.4 software will be used for statistical analysis. Heterogeneity will be analysed using I2statistics. Mean difference or standardised mean difference with 95% CI and p value will be used to calculate treatment effect for outcome variables.Ethics and disseminationEthical approval is not required because this systematic review and meta-analysis is based on previously published data. Final results will be published in peer-reviewed journals and presented at relevant conferences and events.PROSPERO registration numberCRD42022306033.
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- 2022
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16. Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study
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Miguel Cendoroglo Neto, Carmen Silvia Valente Barbas, Bento Fortunato Cardoso dos Santos, Leonardo José Rolim Ferraz, Marcele Liliane Pesavento, Karina T. Timenetsky, Sidney Klajner, Gustavo Faissol Janot de Matos, Veronica Neves Fialho Queiroz, Adriano José Pereira, Roberto Rabello Filho, Ricardo Kenji Nawa, Bruno C. Silva, Thais Dias Midega, Claudia Regina Laselva, Vanessa Teich, Raquel Afonso Caserta Eid, Andreia Pardini, Thiago Domingos Corrêa, Ricardo Luiz Cordioli, Moacyr Silva Junior, Felipe Maia de Toledo Piza, Fabricio Rodrigues Torres de Carvalho, and Bruno de Arruda Bravim
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Adult ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Coronavirus infections ,Single Center ,Infecções por coronavírus ,law.invention ,Cohort Studies ,Betacoronavirus ,Betacoronavírus ,law ,Critical care outcomes ,Pandemic ,Hospital discharge ,Medicine ,Humans ,Hospital Mortality ,Mortality ,Pandemics ,Aged ,Retrospective Studies ,Ventilação não invasiva ,Intensive care units ,Oxigenação por membrana extracorpórea ,Extracorporeal membrane oxygenation ,business.industry ,SARS-CoV-2 ,Artigo Original ,COVID-19 ,Retrospective cohort study ,General Medicine ,Intensive care unit ,Respiration, Artificial ,Resultados de cuidados críticos ,Coronavirus ,Coronavírus ,Unidades de terapia intensiva ,Respiração artificial ,Emergency medicine ,Mortalidade ,Resource use ,Original Article ,Respiration, artificial ,business ,Noninvasive ventilation ,Brazil ,Cohort study - Abstract
Objective: To describe clinical characteristics, resource use, outcomes, and to identify predictors of in-hospital mortality of patients with COVID-19 admitted to the intensive care unit. Methods: Retrospective single-center cohort study conducted at a private hospital in São Paulo (SP), Brazil. All consecutive adult (≥18 years) patients admitted to the intensive care unit, between March 4, 2020 and February 28, 2021 were included in this study. Patients were categorized between survivors and non-survivors according to hospital discharge. Results: During the study period, 1,296 patients [median (interquartile range) age: 66 (53-77) years] with COVID-19 were admitted to the intensive care unit. Out of those, 170 (13.6%) died at hospital (non-survivors) and 1,078 (86.4%) were discharged (survivors). Compared to survivors, non-survivors were older [80 (70-88) versus 63 (50-74) years; p
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- 2021
17. The Perme Mobility Index: A new concept to assess mobility level in patients with coronavirus (COVID-19) infection
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Ricardo Kenji Nawa, Raquel Afonso Caserta Eid, Karina T. Timenetsky, C. S. Moreira, Ana Carolina Lazarin, Ary Serpa Neto, Thiago Domingos Corrêa, Andreia Pardini, and Intensive Care Medicine
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Male ,Viral Diseases ,Pulmonology ,Epidemiology ,medicine.medical_treatment ,Single Center ,law.invention ,Cohort Studies ,0302 clinical medicine ,Medical Conditions ,law ,Risk Factors ,Medicine and Health Sciences ,Medicine ,030212 general & internal medicine ,Hospital Mortality ,Musculoskeletal System ,Virus Testing ,Aged, 80 and over ,Multidisciplinary ,Middle Aged ,Intensive care unit ,Patient Discharge ,Hospitals ,Hospitalization ,Intensive Care Units ,Treatment Outcome ,Infectious Diseases ,Female ,Anatomy ,Brazil ,Cohort study ,Research Article ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Critical Care ,Science ,Hospital mortality ,03 medical and health sciences ,Respiratory Disorders ,Diagnostic Medicine ,Internal medicine ,Humans ,Renal replacement therapy ,Mobility Limitation ,Pandemics ,Aged ,Retrospective Studies ,Mechanical ventilation ,business.industry ,SARS-CoV-2 ,COVID-19 ,Biology and Life Sciences ,030208 emergency & critical care medicine ,Retrospective cohort study ,Covid 19 ,Respiration, Artificial ,Health Care ,Health Care Facilities ,Medical Risk Factors ,Respiratory Infections ,business - Abstract
Introduction The Coronavirus Disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. Data on the mobility level of patients with COVID-19 in the intensive care unit (ICU) are needed. Objective To describe the mobility level of patients with COVID-19 admitted to the ICU and to address factors associated with mobility level at the time of ICU discharge. Methods Single center, retrospective cohort study. Consecutive patients admitted to the ICU with confirmed COVID-19 infection were analyzed. The mobility status was assessed by the Perme Score at admission and discharge from ICU with higher scores indicating higher mobility level. The Perme Mobility Index (PMI) was calculated [PMI = ΔPerme Score (ICU discharge–ICU admission)/ICU length of stay]. Based on the PMI, patients were divided into two groups: “Improved” (PMI > 0) and “Not improved” (PMI ≤ 0). Results A total of 136 patients were included in this analysis. The hospital mortality rate was 16.2%. The Perme Score improved significantly when comparing ICU discharge with ICU admission [20.0 (7–28) points versus 7.0 (0–16) points; P < 0.001]. A total of 88 patients (64.7%) improved their mobility level during ICU stay, and the median PMI of these patients was 1.5 (0.6–3.4). Patients in the improved group had a lower duration of mechanical ventilation [10 (5–14) days versus 15 (8–24) days; P = 0.021], lower hospital length of stay [25 (12–37) days versus 30 (11–48) days; P < 0.001], and lower ICU and hospital mortality rate. Independent predictors for mobility level were lower age, lower Charlson Comorbidity Index, and not having received renal replacement therapy. Conclusion Patients’ mobility level was low at ICU admission; however, most patients improved their mobility level during ICU stay. Risk factors associated with the mobility level were age, comorbidities, and use of renal replacement therapy.
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- 2021
18. High Flow Nasal Cannula in a Low-Income Country: Experience of a Single Center in Brazil
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Karina T. Timenetsky, Raquel Afonso Caserta Eid, E. Colucci, F.S. Leite, and J.B. Silva
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Low income ,medicine.medical_specialty ,business.industry ,Medicine ,business ,Single Center ,High flow ,medicine.disease_cause ,Nasal cannula ,Surgery - Published
- 2020
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19. Um programa estruturado de reabilitação para pacientes hospitalizados com COVID-19
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Caroline Gomes Mól, Karina Tavares Timenetsky, Cilene Saghabi de Medeiros Silva, Camila Nascimento, Raquel Afonso Caserta Eid, and Ricardo Kenji Nawa
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Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2022
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20. Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
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Alejandra G. Garrido, Bárbara Vieira Carneiro, Fabricio Rodrigues Torres de Carvalho, Ana Claudia Ferraz de Almeida, Carmen Silvia Valente Barbas, Karina T. Timenetsky, Roseny dos Reis Rodrigues, Moacyr Silva Júnior, Farah Christina de La Cruz Scarin, Adriano José Pereira, Thiago Domingos Corrêa, Ricardo Luiz Cordioli, Roberto Rabello Filho, Hélio Penna Guimarães, Bruno de Arruda Bravim, Antonio Eduardo Pesaro, Carla Luciana Batista, Gustavo Faissol Janot de Matos, Marcele Liliane Pesavento, Frederico Polito Lomar, M. Assuncao, Rodrigo Martins Brandão, Marcelo Franken, João Carlos de Campos Guerra, Cilene S.D.M. Silva, Leonardo José Rolim Ferraz, Ricardo Kenji Nawa, and Raquel Afonso Caserta Eid
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medicine.medical_specialty ,intensive care units ,Critical Illness ,Pneumonia, Viral ,coronavirus ,lcsh:Medicine ,macromolecular substances ,Severe Acute Respiratory Syndrome ,Special Article ,Betacoronavirus ,03 medical and health sciences ,0302 clinical medicine ,Artigo Especial ,respiratory insufficiency ,medicine ,Humans ,030212 general & internal medicine ,Letter to the Editor ,Pandemics ,Gynecology ,Respiratory distress syndrome, adult ,Intensive care units ,SARS-CoV-2 ,business.industry ,lcsh:R ,COVID-19 ,General Medicine ,Síndrome do desconforto respiratório do adulto ,Respiration, Artificial ,Checklist ,Coronavírus ,Coronavirus ,Unidades de terapia intensiva ,covid-19 ,030220 oncology & carcinogenesis ,Practice Guidelines as Topic ,Carta Ao Editor ,Medicine ,Insuficiência respiratória ,Coronavirus Infections ,business ,Respiratory insufficiency ,respiratory distress syndrome, adult - Abstract
In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome. Subsequently, COVID-19 was attributed to a new betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Approximately 20% of patients diagnosed as COVID-19 develop severe forms of the disease, including acute hypoxemic respiratory failure, severe acute respiratory syndrome, acute respiratory distress syndrome and acute renal failure and require intensive care. There is no randomized controlled clinical trial addressing potential therapies for patients with confirmed COVID-19 infection at the time of publishing these treatment recommendations. Therefore, these recommendations are based predominantly on the opinion of experts (level C of recommendation).
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- 2020
21. Adaptation to different noninvasive ventilation masks in critically ill patients
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Eliezer Silva, Carla Maekawa, Renata Matos da Silva, Karina T. Timenetsky, Sandra Sayuri Kanda, Liane Hirano Shigemichi, Raquel Afonso Caserta Eid, and Renata Cristina Miranda Neves
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Pulmonary and Respiratory Medicine ,Adult ,Male ,medicine.medical_specialty ,Time Factors ,Ventilacao com pressao positiva intermitente ,Critical Illness ,Young Adult ,Máscaras ,Intensive care ,Insuficiencia respiratoria ,medicine ,Humans ,Acute respiratory failure ,Intermittent positive-pressure ventilation ,Intensive care medicine ,Aged ,Aged, 80 and over ,lcsh:RC705-779 ,Noninvasive Ventilation ,Artigos Originais ,business.industry ,Critically ill ,Masks ,Equipment Design ,Original Articles ,lcsh:Diseases of the respiratory system ,Middle Aged ,Ventilação com pressão positiva intermitente ,Adaptation, Physiological ,Face masks ,Intermittent positive pressure ventilation ,Regimen ,Intensive Care Units ,Emergency medicine ,Acute Disease ,Mascaras ,Noninvasive ventilation ,Female ,Insuficiência respiratória ,business ,Respiratory insufficiency - Abstract
OBJECTIVE: To identify which noninvasive ventilation (NIV) masks are most commonly used and the problems related to the adaptation to such masks in critically ill patients admitted to a hospital in the city of São Paulo, Brazil. METHODS: An observational study involving patients ≥ 18 years of age admitted to intensive care units and submitted to NIV. The reason for NIV use, type of mask, NIV regimen, adaptation to the mask, and reasons for non-adaptation to the mask were investigated. RESULTS: We evaluated 245 patients, with a median age of 82 years. Acute respiratory failure was the most common reason for NIV use (in 71.3%). Total face masks were the most commonly used (in 74.7%), followed by full face masks and near-total face masks (in 24.5% and 0.8%, respectively). Intermittent NIV was used in 82.4% of the patients. Adequate adaptation to the mask was found in 76% of the patients. Masks had to be replaced by another type of mask in 24% of the patients. Adequate adaptation to total face masks and full face masks was found in 75.5% and 80.0% of the patients, respectively. Non-adaptation occurred in the 2 patients using near-total facial masks. The most common reason for non-adaptation was the shape of the face, in 30.5% of the patients. CONCLUSIONS: In our sample, acute respiratory failure was the most common reason for NIV use, and total face masks were the most commonly used. The most common reason for non-adaptation to the mask was the shape of the face, which was resolved by changing the type of mask employed. OBJETIVO: Identificar as interfaces de ventilação não invasiva (VNI) mais utilizadas e os eventuais problemas relacionados a sua adaptação em pacientes críticos internados em um hospital na cidade de São Paulo, SP. MÉTODOS: Estudo observacional, com pacientes acima de 18 anos admitidos nas unidades de pacientes graves que usaram VNI. Foram coletados a causa de uso da VNI, interface utilizada, esquema de uso da VNI, adaptação e motivos para a falta de adaptação à interface. RESULTADOS: Avaliamos 245 pacientes, com média de idade de 82 anos. A insuficiência respiratória aguda foi a causa mais frequente de uso da VNI (71,3%). A interface mais utilizada foi a máscara facial total (74,7%), seguida por máscara facial e máscara facial quase total (24,5% e 0,8%, respectivamente). Em 82,4% dos pacientes, a VNI foi utilizada por períodos. A adaptação adequada à interface ocorreu em 76% dos pacientes. As máscaras tiveram de ser trocadas em 24% dos pacientes. Houve adaptação adequada à máscara facial total e à máscara facial em 75,5% e em 80,0% dos pacientes, respectivamente. A adaptação foi inadequada nos 2 pacientes que utilizaram a máscara facial quase total. A causa mais frequente da falta de adaptação foi o formato da face, em 30,5% dos pacientes. CONCLUSÕES: Nesta amostra, a insuficiência respiratória aguda foi a causa mais frequente de uso da VNI, e a máscara facial total foi a interface mais utilizada. A causa mais comum da falta de adaptação à máscara foi o formato da face, que foi resolvida após a troca da interface.
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- 2013
22. Successful prevention of tracheostomy associated pneumonia in step-down units
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Joyce Kelly Silva Barreto, Alexandre R. Marra, Raquel Afonso Caserta Eid, Michael B. Edmond, Fernanda Domingues, Claudia Vallone Silva, Oscar Fernando Pavão dos Santos, and Ângela Tavares Paes
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medicine.medical_specialty ,Epidemiology ,medicine.medical_treatment ,Psychological intervention ,Tracheostomy ,Tracheotomy ,Pneumonia, Bacterial ,medicine ,Humans ,Intensive care medicine ,Aged ,Mechanical ventilation ,Infection Control ,business.industry ,Incidence ,Health Policy ,Incidence (epidemiology) ,Public Health, Environmental and Occupational Health ,Pneumonia, Ventilator-Associated ,Interrupted time series ,medicine.disease ,Disease control ,Pneumonia ,Infectious Diseases ,Health Services Research ,business - Abstract
Background Prevention of health care-associated infections is well described in critical care. However, surveillance in step-down unit (SDU) patients who need intermediate care with bilevel mechanical ventilation pressure through tracheotomy needs to be better understood. We evaluated the implementation of preventive measures in SDU over 2 different periods on device (bilevel mechanical ventilation)-associated pneumonia. Methods A quasi-experimental, interrupted time series study was conducted in SDUs. Interventions were implemented to optimize the prevention of pneumonia associated with tracheostomy and evaluated in 2 phases. From January to October of 2007 (phase 1), some practices recommended by the Centers for Disease Control and Prevention were implemented, and the epidemiology unit carried out surveillance for pneumonia associated with tracheostomy. From November of 2007 to August of 2008 (phase 2) the same practices recommended by the Centers for Disease Control and Prevention were followed, but, in addition, the assessment of these processes as well as bedside interventions were initiated. Results The mean incidence density of tracheostomy associated pneumonia per 1,000 tracheostomy-days in the SDUs was 6.0 in phase 1 and 0.7 in phase 2, P = .002. Conclusion Reducing pneumonia associated with tracheostomy is a continuous multidisciplinary process that involves the measurement of multiple performance metrics.
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- 2011
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23. Prevalence of burnout syndrome among physiotherapist working in intensive care units and step down unit
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Raquel Afonso Caserta Eid, D Carnieli-Cazati, CA Castro, and Karina T. Timenetsky
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Health professionals ,business.industry ,health care facilities, manpower, and services ,Burnout syndrome ,education ,Critical Care and Intensive Care Medicine ,Unit (housing) ,Type of service ,Nursing ,health services administration ,Intensive care ,Poster Presentation ,Medicine ,business ,psychological phenomena and processes ,Mental suffering - Abstract
Burnout Syndrome is defined as a condition of mental suffering work-related and associated with physiological changes resulting from stress. The burnout syndrome is experienced mainly by health professionals involved in care activities, where the greatest demand for this type of service is to deal with the emotional needs of the other, under stress.
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- 2015
24. Smart Care™ versus respiratory physiotherapy–driven manual weaning for critically ill adult patients: a randomized controlled trial
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Elivane da Silva Victor, Raquel Afonso Caserta Eid, Guilherme Schettino, Gustavo Faissol Janot de Matos, Eliezer Silva, Carmen Silvia Valente Barbas, Talita Pieri, Cilene Saghabi, Carolina D. Sant’Ana, Erica A. Giovanetti, Renata Henn, Corinne Taniguchi, and Karina T. Timenetsky
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Critical Illness ,Pressure support ventilation ,Critical Care and Intensive Care Medicine ,law.invention ,Randomized controlled trial ,law ,medicine ,Weaning ,Humans ,Continuous positive airway pressure ,Prospective Studies ,Respiratory physiotherapy ,Intensive care medicine ,Prospective cohort study ,Physical Therapy Modalities ,Aged ,Aged, 80 and over ,Adult patients ,business.industry ,Critically ill ,Research ,Middle Aged ,Decision Support Systems, Clinical ,Respiration, Artificial ,Intensive Care Units ,Airway Extubation ,Female ,business ,Ventilator Weaning ,Brazil - Abstract
Introduction A recent meta-analysis showed that weaning with SmartCare™ (Dräger, Lübeck, Germany) significantly decreased weaning time in critically ill patients. However, its utility compared with respiratory physiotherapist–protocolized weaning is still a matter of debate. We hypothesized that weaning with SmartCare™ would be as effective as respiratory physiotherapy–driven weaning in critically ill patients. Methods Adult critically ill patients mechanically ventilated for more than 24 hours in the adult intensive care unit of the Albert Einstein Hospital, São Paulo, Brazil, were randomly assigned to be weaned either by progressive discontinuation of pressure support ventilation (PSV) with SmartCare™. Demographic data, respiratory function parameters, level of PSV, tidal volume (VT), positive end-expiratory pressure (PEEP), inspired oxygen fraction (FiO2), peripheral oxygen saturation (SpO2), end-tidal carbon dioxide concentration (EtCO2) and airway occlusion pressure at 0.1 second (P0.1) were recorded at the beginning of the weaning process and before extubation. Mechanical ventilation time, weaning duration and rate of extubation failure were compared. Results Seventy patients were enrolled 35 in each group. There was no difference between the two groups concerning age, sex or diagnosis at study entry. There was no difference in maximal inspiratory pressure, maximal expiratory pressure, forced vital capacity or rapid shallow breathing index at the beginning of the weaning trial. PEEP, VT, FiO2, SpO2, respiratory rate, EtCO2 and P0.1 were similar between the two groups, but PSV was not (median: 8 vs. 10 cmH2O; p =0.007). When the patients were ready for extubation, PSV (8 vs. 5 cmH2O; p =0.015) and PEEP (8 vs. 5 cmH2O; p p =0.467) and extubation failure (2 vs. 2; p =1.00) were similar between the two groups. Weaning duration was shorter in the respiratory physiotherapy–driven weaning group (60 [50–80] minutes vs. 110 [80–130] minutes; p Conclusion A respiratory physiotherapy–driven weaning protocol can decrease weaning time compared with an automatic system, as it takes into account individual weaning difficulties. Trial registration Clinicaltrials.gov Identifier: NCT02122016. Date of Registration: 27 August 2013.
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- 2015
25. Design of an instrument to measure the quality of care in Physical Therapy
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Cristiane do Prado, Paola Bruno de Araújo Andreoli, Raquel Afonso Caserta Eid, Claudia Talerman, Leny Vieira Cavalheiro, and Fátima Cristina Martorano Gobbi
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Physical Therapy Specialty ,Service (systems architecture) ,medicine.medical_specialty ,Measurements, methods and theories ,Quality Assurance, Health Care ,Process (engineering) ,Medidas, métodos e teorias ,lcsh:Medicine ,Health Economics and Management ,Personalization ,Qualidade da assistência à saúde ,Brainstorming ,Animals ,Humans ,Medicine ,Lean Six Sigma ,Set (psychology) ,Physical Therapy Modalities ,Fisioterapia ,Quality Indicators, Health Care ,Measure (data warehouse) ,business.industry ,lcsh:R ,Reproducibility of Results ,General Medicine ,Benchmarking ,Equipment and Supplies ,Gestão Economia em Saúde ,Physical therapy ,Quality of health care ,Guideline Adherence ,business ,Brazil ,Program Evaluation - Abstract
Objective: To design an instrument composed of domains that would demonstrate physical therapy activities and generate a consistent index to represent the quality of care in physical therapy. Methods: The methodology Lean Six Sigma was used to design the tool. The discussion involved seven different management groups staff. By means of brainstorming and Cause & Effect Matrix, we set up the process map. Results: Five requirements composed the quality of care index in physical therapy, after application of the tool called Cause & Effect Matrix. The following requirements were assessed: physical therapist performance, care outcome indicator, adherence to physical therapy protocols, measure whether the prognosis and treatment outcome was achieved and Infrastructure. Conclusion: The proposed design allowed evaluating several items related to physical therapy service, enabling customization, reproducibility and benchmarking with other organizations. For management, this index provides the opportunity to identify areas for improvement and the strengths of the team and process of physical therapy care. RESUMO Objetivo: Delinear um instrumento composto de domínios que demonstrassem a atividade da área da Fisioterapia e que gerassem um índice consistente, capaz de representar a qualidade da assistência fisioterapêutica. Métodos: Para o delineamento do instrumento, utilizamos a metodologia denominada Lean Seis Sigma. A discussão envolveu sete grupos de gestão diferentes e desta equipe de trabalho. Por meio das ferramentas de brainstorm e Matriz de Causa e Efeito, montamos o mapa do processo. Resultados: Cinco requisitos constituíram o índice de qualidade de assistência da Fisioterapia, após a aplicação da ferramenta denominada Matriz de Causa e Efeito. Os requisitos foram avaliação individual do desempenho do fisioterapeuta, indicador de resultado de assistência, avaliação da adesão da Fisioterapia nos protocolos, medir se o prognóstico e resultado de tratamento foi alcançado, e infraestrutura. Conclusão: O desenho proposto permitiu avaliar vários itens que compunhamo serviço de Fisioterapia, possibilitando customização, reprodutibilidade e benchmark entre as instituições. Para a gestão, esse índice deve proporcionar a oportunidade de identificar os pontos de melhoria, e os pontos fortes da equipe e processo de assistência da Fisioterapia.
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- 2015
26. Implementation of an educational program to decrease the tidal volume size in a general intensive care unit: a pilot study
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Carolina Sant’Anna A. Azevedo, Raquel Afonso Caserta Eid, Nathalia G. Correa, Corinne Taniguchi, Karina T. Timenetsky, Cilene Saghabi, Ary Serpa Neto, Guilherme Schettino, Denise Carnieli-Cazati, and Graduate School
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Male ,medicine.medical_specialty ,Pain medicine ,MEDLINE ,Pilot Projects ,Critical Care and Intensive Care Medicine ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Patient Education as Topic ,law ,Anesthesiology ,Tidal Volume ,medicine ,Humans ,RESPIRATORY DISTRESS SYNDROME ADULT ,Tidal volume ,Respiratory Distress Syndrome ,business.industry ,030208 emergency & critical care medicine ,Middle Aged ,Intensive care unit ,Intensive Care Units ,030228 respiratory system ,Emergency medicine ,Female ,business ,Educational program - Published
- 2016
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27. High Prevalence of Respiratory Muscle Weakness in Hospitalized Acute Heart Failure Elderly Patients
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Raquel Afonso Caserta Eid, Louise Helena Rodrigues Gonçalves, Pedro Verissimo, Angela Shu Yun Yang, Thaisa Juliana André Casalaspo, and Karina T. Timenetsky
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medicine.medical_specialty ,Multidisciplinary ,Ejection fraction ,business.industry ,Strength training ,lcsh:R ,lcsh:Medicine ,Hemodynamics ,Muscle weakness ,Brain natriuretic peptide ,medicine.disease ,Surgery ,Heart failure ,Internal medicine ,Respiratory muscle ,Cardiology ,Medicine ,lcsh:Q ,Respiratory system ,medicine.symptom ,lcsh:Science ,business ,Research Article - Abstract
Introduction Respiratory Muscle Weakness (RMW) has been defined when the maximum inspiratory pressure (MIP) is lower than 70% of the predictive value. The prevalence of RMW in chronic heart failure patients is 30 to 50%. So far there are no studies on the prevalence of RMW in acute heart failure (AHF) patients. Objectives Evaluate the prevalence of RMW in patients admitted because of AHF and the condition of respiratory muscle strength on discharge from the hospital. Methods Sixty-three patients had their MIP measured on two occasions: at the beginning of the hospital stay, after they had reached respiratory, hemodynamic and clinical stability and before discharge from the hospital. The apparatus and technique to measure MIP were adapted because of age-related limitations of the patients. Data on cardiac ejection fraction, ECG, brain natriuretic peptide (BNP) levels and on the use of noninvasive ventilation (NIV) were collected. Results The mean age of the 63 patients under study was 75 years. On admission the mean ejection fraction was 33% (95% CI: 31–35) and the BNP hormone median value was 726.5 pg/ml (range: 217 to 2283 pg/ml); 65% of the patients used NIV. The median value of MIP measured after clinical stabilization was -52.7 cmH2O (range: -20 to -120 cmH2O); 76% of the patients had MIP values below 70% of the predictive value. On discharge, after a median hospital stay of 11 days, the median MIP was -53.5 cmH2O (range:-20 to -150 cmH2O); 71% of the patients maintained their MIP values below 70% of the predictive value. The differences found were not statistically significant. Conclusion Elderly patients admitted with AHF may present a high prevalence of RMW on admission; this condition may be maintained at similar levels on discharge in a large percentage of these patients, even after clinical stabilization of the heart condition.
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- 2015
28. Brazilian recommendations of mechanical ventilation 2013. Part 2
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Marco Antonio Soares Reis, Felipe Saddy, Carmen Silvia Valente Barbas, Péricles Almeida Delfino Duarte, Marcos Tavares, M Damasceno, Mara Ambrosina de Oliveira Vargas, Luciana Passuello do Vale Prodomo, Bruno de Arruda Bravim, Nazah Cherif Mohamad Youssef, Desanka Dragosavac, Diogo Oliveira Toledo, Bruno do Valle Pinheiro, Ary Serpa Neto, Eliezer Silva, Marcelo Brito Passos Amato, Juliana Carvalho Ferreira, Sandra Justino, Gustavo Faissol Janot de Matos, Eduardo L. V. Costa, Raquel Afonso Caserta Eid, Fábio Ferreira Amorim, Arthur Vianna, José Mario Meira Teles, Ludhmila Abrahão Hajjar, Josue Almeida Victorino, Marcelo Park, Alexandre Biasi Cavalcanti, Luiz Cláudio Martins, Corine Taniguchi, Ronaldo Adib Kairalla, Octavio Messeder, Bruno Franco Mazza, Jorge Luis dos Sanots Valiatti, Murillo Santucci Cesar de Assunção, Ana Maria Casati Gama, Carlos Toufen Junior, Sérgio Nogueira Nemer, Verônica Amado, Alexandre Marini Ísola, Simone Barbosa Romero, Marta Cristina Paulette Damasceno, Ricardo Goulart Rodrigues, Rodrigo Francisco de Jesus, Luiz Marcelo Sá Malbouisson, Carlos Roberto Ribeiro de Carvalho, Gisele Sampaio Silva, Paulo José Zimmermann Teixeira, Antonio Carlos Magalhães Duarte, Pedro Caruso, Débora Dutra da Silveira Mazza, Eliana Bernardete Caser, Márcia Jacomelli, Augusto Manoel de Carvalho Farias, Cid Marcos David, João Claudio Emmerich, Marcelo Alcantara Holanda, and Filomena Regina Barbosa Gomes Galas
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Pulmonary and Respiratory Medicine ,Recomendações ,Critical Care ,Mechanical Ventilation ,Critical Illness ,medicine.medical_treatment ,MEDLINE ,Recommendations ,Ventilação Mecânica ,Critical Care and Intensive Care Medicine ,law.invention ,Idiopathic pulmonary fibrosis ,Special Article ,Randomized controlled trial ,law ,Artigo Especial ,Intensive care ,International literature ,Humans ,Medicine ,Respiratory system ,Positive pressure ventilation ,Quality of Health Care ,Mechanical ventilation ,Medical education ,Evidence-Based Medicine ,business.industry ,Subject (documents) ,General Medicine ,medicine.disease ,Plenary session ,Intensive care unit ,Respiration, Artificial ,Insuficiência Respiratória ,Intensive Care Units ,Anesthesia ,Practice Guidelines as Topic ,Critical illness ,Special Articles ,Respiratory Insufficiency ,business ,Brazil - Abstract
Perspectives on invasive and noninvasive ventilatory support for critically ill patients are evolving, as much evidence indicates that ventilation may have positive effects on patient survival and the quality of the care provided in intensive care units in Brazil. For those reasons, the Brazilian Association of Intensive Care Medicine (Associação de Medicina Intensiva Brasileira - AMIB) and the Brazilian Thoracic Society (Sociedade Brasileira de Pneumologia e Tisiologia - SBPT), represented by the Mechanical Ventilation Committee and the Commission of Intensive Therapy, respectively, decided to review the literature and draft recommendations for mechanical ventilation with the goal of creating a document for bedside guidance as to the best practices on mechanical ventilation available to their members. The document was based on the available evidence regarding 29 subtopics selected as the most relevant for the subject of interest. The project was developed in several stages, during which the selected topics were distributed among experts recommended by both societies with recent publications on the subject of interest and/or significant teaching and research activity in the field of mechanical ventilation in Brazil. The experts were divided into pairs that were charged with performing a thorough review of the international literature on each topic. All the experts met at the Forum on Mechanical Ventilation, which was held at the headquarters of AMIB in São Paulo on August 3 and 4, 2013, to collaboratively draft the final text corresponding to each sub-topic, which was presented to, appraised, discussed and approved in a plenary session that included all 58 participants and aimed to create the final document.
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- 2014
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29. Brazilian recommendations of mechanical ventilation 2013. Part I
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Luiz Cláudio Martins, Sandra Justino, Felipe Saddy, Filomena Regina Barbosa Gomes Galas, Sérgio Nogueira Nemer, Eduardo L. V. Costa, Marco Antonio Soares Reis, Eliana Bernardete Caser, Ludhmila Abrahão Hajjar, Josue Almeida Victorino, Carlos Toufen Junior, Augusto Manoel de Carvalho Farias, Verônica Amado, Ana Maria Casati Gama, Antonio Carlos Magalhães Duarte, Carmen Silvia Valente Barbas, Ronaldo Adib Kairalla, Mara Ambrosina de Oliveira Vargas, Luciana Passuello do Vale Prodomo, Marcelo Alcântara Holanda, Murillo Santucci Cesar de Assunção, Bruno do Valle Pinheiro, Corine Taniguchi, Marta Cristina Paulette Damasceno, Alexandre Marini Ísola, Jorge Luis dos Santos Valiatti, Marcos Tavares, Bruno de Arruda Bravim, Luiz Marcelo Sá Malbouisson, Alexandre Biasi Cavalcanti, Nazah Cherif Mohamad Youssef, Ricardo Goulart Rodrigues, Eliezer Silva, Simone Barbosa Romero, José Mario Meira Teles, Raquel Afonso Caserta Eid, Fábio Ferreira Amorim, Diogo Oliveira Toledo, Desanka Dragosavac, M Damasceno, Cid Marcos David, Márcia Jacomelli, Octavio Messeder, João Claudio Emmerich, Ary Serpa Neto, Péricles Almeida Delfino Duarte, Marcelo Brito Passos Amato, Gustavo Faissol Janot de Matos, Débora Dutra da Silveira Mazza, Carlos Roberto Ribeiro de Carvalho, Gisele Sampaio Silva, Paulo José Zimmermann Teixeira, Bruno Franco Mazza, Pedro Caruso, Arthur Vianna, Rodrigo Francisco de Jesus, Marcelo Park, and Juliana Carvalho Ferreira
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Critical Care ,business.industry ,Critical Illness ,General Medicine ,Critical Care and Intensive Care Medicine ,Respiration, Artificial ,Special Article ,Intensive Care Units ,Practice Guidelines as Topic ,Humans ,Medicine ,business ,Humanities ,Brazil ,Quality of Health Care - Abstract
O suporte ventilatório artificial invasivo e não invasivo ao paciente crítico tem evoluído e inúmeras evidências têm surgido, podendo ter impacto na melhora da sobrevida e da qualidade do atendimento oferecido nas unidades de terapia intensiva no Brasil. Isto posto, a Associação de Medicina Intensiva Brasileira (AMIB) e a Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) - representadas pelo seus Comitê de Ventilação Mecânica e Comissão de Terapia Intensiva, respectivamente, decidiram revisar a literatura e preparar recomendações sobre ventilação mecânica objetivando oferecer aos associados um documento orientador das melhores práticas da ventilação mecânica na beira do leito, baseado nas evidencias existentes, sobre os 29 subtemas selecionados como mais relevantes no assunto. O projeto envolveu etapas visando distribuir os subtemas relevantes ao assunto entre experts indicados por ambas as sociedades que tivessem publicações recentes no assunto e/ou atividades relevantes em ensino e pesquisa no Brasil na área de ventilação mecânica. Esses profissionais, divididos por subtemas em duplas, responsabilizaram-se por fazer revisão extensa da literatura mundial sobre cada subtema. Reuniram-se todos no Forum de Ventilação Mecânica na sede da AMIB em São Paulo, em 03 e 04 de agosto de 2013 para finalização conjunta do texto de cada subtema e apresentação, apreciação, discussão e aprovação em plenária pelos 58 participantes, permitindo a elaboração de um documento final. Perspectives on invasive and noninvasive ventilatory support for critically ill patients are evolving, as much evidence indicates that ventilation may have positive effects on patient survival and the quality of the care provided in intensive care units in Brazil. For those reasons, the Brazilian Association of Intensive Care Medicine (Associação de Medicina Intensiva Brasileira - AMIB) and the Brazilian Thoracic Society (Sociedade Brasileira de Pneumologia e Tisiologia - SBPT), represented by the Mechanical Ventilation Committee and the Commission of Intensive Therapy, respectively, decided to review the literature and draft recommendations for mechanical ventilation with the goal of creating a document for bedside guidance as to the best practices on mechanical ventilation available to their members. The document was based on the available evidence regarding 29 subtopics selected as the most relevant for the subject of interest. The project was developed in several stages, during which the selected topics were distributed among experts recommended by both societies with recent publications on the subject of interest and/or significant teaching and research activity in the field of mechanical ventilation in Brazil. The experts were divided into pairs that were charged with performing a thorough review of the international literature on each topic. All the experts met at the Forum on Mechanical Ventilation, which was held at the headquarters of AMIB in São Paulo on August 3 and 4, 2013, to collaboratively draft the final text corresponding to each sub-topic, which was presented to, appraised, discussed and approved in a plenary session that included all 58 participants and aimed to create the final document.
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- 2014
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30. Profile of reintubated patients submitted to daily weaning screen and spontaneous breathing trial in a general ICU
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Corinne Taniguchi, PA Pellegrini, D Carineli-Cazati, Karina T. Timenetsky, Gfj Matos, Csm Silva, Erica A. Giovanetti, Raquel Afonso Caserta Eid, and NR Machado
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Artificial ventilation ,Mechanical ventilation ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Poster Presentation ,Emergency medicine ,Breathing ,Medicine ,Weaning ,Critical Care and Intensive Care Medicine ,business ,Spontaneous breathing trial - Abstract
Mechanical ventilation (MV) weaning is the transition of artificial ventilation to spontaneous breathing of patients intubated for more than 24 hours. Reintubation may occur, even if the weaning process has been well conducted, in 13 to 19% of the extubated patients. Daily weaning screen and spontaneous breathing trial are widely used to evaluate patients ready to be weaned, although a reintubation risk may occur [1]. The objective of this study was to verify the profile of patients that failed the weaning process and needed to be reintubated.
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- 2013
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31. Low mechanical ventilation times and reintubation rates associated with a specific weaning protocol in an intensive care unit setting: a retrospective study
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Carmen Silvia Valente Barbas, Gustavo Faissol Janot de Matos, Cilene S.D.M. Silva, Karina T. Timenetsky, Sedila Calegaro, Carolina Sant’Anna A. Azevedo, Ricardo Stus, Corinne Taniguchi, and Raquel Afonso Caserta Eid
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Adult ,Male ,Time Factors ,medicine.medical_treatment ,Statistics, Nonparametric ,law.invention ,Interquartile range ,law ,Ventilator weaning ,Intubation, Intratracheal ,Humans ,Medicine ,Intubation ,Weaning ,Aged ,Retrospective Studies ,Aged, 80 and over ,Mechanical ventilation ,lcsh:R5-920 ,business.industry ,Mortality rate ,Clinical protocols ,Reproducibility of Results ,Retrospective cohort study ,General Medicine ,Middle Aged ,Clinical Science ,Respiration, Artificial ,Intensive care unit ,Intensive Care Units ,Treatment Outcome ,Anesthesia ,Rapid shallow breathing index ,Female ,lcsh:Medicine (General) ,business ,Brazil - Abstract
OBJECTIVES: A number of complications exist with invasive mechanical ventilation and with the use of and withdrawal from prolonged ventilator support. The use of protocols that enable the systematic identification of patients eligible for an interruption in mechanical ventilation can significantly reduce the number of complications. This study describes the application of a weaning protocol and its results. METHODS: Patients who required invasive mechanical ventilation for more than 24 hours were included and assessed daily to identify individuals who were ready to begin the weaning process. RESULTS: We studied 252 patients with a median mechanical ventilation time of 3.7 days (interquartile range of 1 to 23 days), a rapid shallow breathing index value of 48 (median), a maximum inspiratory pressure of 40 cmH(2)0, and a maximum expiratory pressure of 40 cm H(2)0 (median). Of these 252 patients, 32 (12.7%) had to be reintubated, which represented weaning failure. Noninvasive ventilation was used postextubation in 170 (73%) patients, and 15% of these patients were reintubated, which also represented weaning failure. The mortality rate of the 252 patients studied was 8.73% (22), and there was no significant difference in the age, gender, mechanical ventilation time, and maximum inspiratory pressure between the survivors and nonsurvivors. CONCLUSIONS: The use of a specific weaning protocol resulted in a lower mechanical ventilation time and an acceptable reintubation rate. This protocol can be used as a comparative index in hospitals to improve the weaning system, its monitoring and the informative reporting of patient outcomes and may represent a future tool and source of quality markers for patient care.
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- 2012
32. NAVA And Diaphragmatic Electrical Stimulation Improved Diaphragm Paresis And Mechanical Ventilation Weaning Of A Liver Transplant Patient: Case Report
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Gustavo Faissol Janot de Matos, Corinne Taniguchi, Raquel Afonso Caserta Eid, Cilene S.D.M. Silva, Erica A. Giovanetti, Camila N. Coelho, Karina T. Timenetsky, and Angela S. Y. Yang
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Mechanical ventilation ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Diaphragmatic breathing ,Stimulation ,Diaphragm (structural system) ,Surgery ,Anesthesia ,medicine ,Weaning ,Transplant patient ,medicine.symptom ,business ,Paresis - Published
- 2012
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33. Noninvasive Ventilation Failure Is Associate With Poor Outcomes In Critically Ill Patients With Acute Respiratory Failure
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Carmen Silvia Valente Barbas, Thiago Domingos Corrêa, Cilene Saghabi, Lúbia Caus de Morais, Corinne Taniguchi, Paula Rodrigues Sanches, and Raquel Afonso Caserta Eid
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medicine.medical_specialty ,business.industry ,Critically ill ,medicine ,Noninvasive ventilation ,Acute respiratory failure ,Intensive care medicine ,business - Published
- 2012
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34. Smart Care Profile During Spontaneous Breathing Trial In Mechanically Ventilated Patients
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Cilene S.D.M. Silva, Carmen Silvia Valente Barbas, Raquel Afonso Caserta Eid, Erica A. Giovanetti, Sandra Sayuri Kanda, Renata Henn Moura, Talita P. Stuchi, Karina T. Timenetsky, and Corinne Taniguchi
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medicine.medical_specialty ,business.industry ,medicine ,Intensive care medicine ,business ,Spontaneous breathing trial - Published
- 2012
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35. Noninvasive Ventilation Inside The Cath Lab Can Be An Effective And Safe Alternative For Patients With Acute Respiratory Failure
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Eduardo Colucci, Daniela R. Alves, Pedro Verissimo, Karina T. Timenetsky, Daniela H.R. Goncalves, and Raquel Afonso Caserta Eid
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medicine.medical_specialty ,Cath lab ,business.industry ,Medicine ,Noninvasive ventilation ,Acute respiratory failure ,business ,Intensive care medicine - Published
- 2012
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36. Early Mobility In The ICU - A Multiprofessional Team Perspective
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Erica A. Giovanetti, Cilene S.D.M. Silva, Raquel Afonso Caserta Eid, Caroline M. Souza, and Karina T. Timenetsky
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Nursing ,Perspective (graphical) ,Sociology - Published
- 2012
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37. Role Of Physiotherapy For Critically Ill Patients In The ICU
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Cilene S.D.M. Silva, Corinne Taniguchi, Raquel Afonso Caserta Eid, Daniela Nobrega, and Karina T. Timenetsky
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medicine.medical_specialty ,Critically ill ,business.industry ,medicine ,Intensive care medicine ,business - Published
- 2012
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38. Low Adverse Event Incidence During Intra-Hospital Transportation Of Critically Ill Mechanically Ventilated Patients With A Multidisciplinary Team
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Mariella M. Machado, Kamyla F. Fuhrmann, Rafael Ladeira Rosa Bocchile, Karina T. Timenetsky, Erica A. Giovanetti, and Raquel Afonso Caserta Eid
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medicine.medical_specialty ,business.industry ,Critically ill ,Incidence (epidemiology) ,Emergency medicine ,medicine ,Medical emergency ,medicine.disease ,Adverse effect ,business ,Multidisciplinary team - Published
- 2012
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39. Impact Of Dialysis Session On Pulmonary Mechanics And Energetic Waste In Mechanically Ventilated Patients
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Paula R. Pelegrino, Oscar Fernando Pavão dos Santos, Karina T. Timenetsky, Marcelino de Souza Durão, Raquel Afonso Caserta Eid, Corinne Taniguchi, Carmen Silvia Valente Barbas, and Cilene S.D.M. Silva
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medicine.medical_specialty ,Pulmonary mechanics ,business.industry ,medicine ,Session (computer science) ,Intensive care medicine ,Dialysis (biochemistry) ,business - Published
- 2010
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40. Use of functional independence measure instrument at a neurological step-down unit
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P.R.P. Hidalgo, N.M. Barros, T. Falsoni, Raquel Afonso Caserta Eid, R. Lobato, P.D. Gaiolla, E.M. Araujo, and C. Talerman
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Neurology ,Computer science ,Neurology (clinical) ,Arithmetic ,Functional Independence Measure ,Unit (housing) - Published
- 2013
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41. Profile of patients followed by physiotherapy at a neurological step-down unit
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N.M. Barros, T. Falsoni, R. Lobato, Raquel Afonso Caserta Eid, C. Talerman, P.D. Gaiolla, P.R.P. Hidalgo, and E.M. Araujo
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medicine.medical_specialty ,Neurology ,business.industry ,Physical therapy ,Medicine ,Neurology (clinical) ,business ,Unit (housing) - Published
- 2013
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42. Use of noninvasive ventilation at a neurological step down unit
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M.C. Kopczynski, K.T. Timenetsky, P.D. Gaiolla, C. Talerman, and Raquel Afonso Caserta Eid
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Neurology ,business.industry ,Anesthesia ,Medicine ,Noninvasive ventilation ,Neurology (clinical) ,business ,Unit (housing) - Published
- 2013
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43. Low incidence of delirium in patients followed by physiotherapists in the ICU
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Karina T. Timenetsky, D Carnieli-Cazati, CS Azevedo, and Raquel Afonso Caserta Eid
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Icu patients ,medicine.medical_specialty ,business.industry ,Incidence (epidemiology) ,Critical Care and Intensive Care Medicine ,behavioral disciplines and activities ,nervous system diseases ,Level of consciousness ,mental disorders ,Assessment methods ,Emergency medicine ,Poster Presentation ,Diagnostic assessment ,Medicine ,Delirium ,In patient ,medicine.symptom ,business ,Intensive care medicine ,Confusion - Abstract
Delirium is an acute temporary and fluctuating mental-organic syndrome, characterized by a global impairment of cognitive function, reduced level of consciousness, attentional deficits and altered sleep-wake cycle, and changes in arousal (hyperactive, hypoactive, or mixed). The Confusion Assessment Method (CAM and CAM ICU) [1] is a diagnostic assessment instrument for delirium and can lead physiotherapeutic treatment, aiming to optimize patient's recovery, reinforce the importance of preventive and therapeutic measures, and appraise the multidisciplinary treatment approach in this severe complicating syndrome. Delirium is present in 20 to 40% of ICU patients. So far we have no data regarding the incidence of delirium at the ICU in patients followed by physiotherapists. The objective of this study was to verify the incidence of delirium through the CAM ICU instrument in ICU patients followed by physiotherapists.
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- 2013
44. Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomized controlled trial
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Eliézer Silva, Elias Knobel, C S Barbas, Corinne Taniguchi, Cilene Saghabi, Raquel Afonso Caserta Eid, Rogério Souza, and Ângela Tavares Paes
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Male ,Icu patients ,Letter ,Time Factors ,Critical Care and Intensive Care Medicine ,law.invention ,Positive-Pressure Respiration ,Randomized controlled trial ,law ,Tidal Volume ,Humans ,Medicine ,Weaning ,Ethics, Medical ,Prospective Studies ,Post operative ,Prospective cohort study ,Tidal volume ,Aged ,Postoperative Care ,business.industry ,Research ,Middle Aged ,Intensive care unit ,Therapy, Computer-Assisted ,Anesthesia ,Breathing ,Female ,business ,Ventilator Weaning ,Brazil - Abstract
Introduction Reduction of automatic pressure support based on a target respiratory frequency or mandatory rate ventilation (MRV) is available in the Taema-Horus ventilator for the weaning process in the intensive care unit (ICU) setting. We hypothesised that MRV is as effective as manual weaning in post-operative ICU patients. Methods There were 106 patients selected in the post-operative period in a prospective, randomised, controlled protocol. When the patients arrived at the ICU after surgery, they were randomly assigned to either: traditional weaning, consisting of the manual reduction of pressure support every 30 minutes, keeping the respiratory rate/tidal volume (RR/TV) below 80 L until 5 to 7 cmH2O of pressure support ventilation (PSV); or automatic weaning, referring to MRV set with a respiratory frequency target of 15 breaths per minute (the ventilator automatically decreased the PSV level by 1 cmH2O every four respiratory cycles, if the patient's RR was less than 15 per minute). The primary endpoint of the study was the duration of the weaning process. Secondary endpoints were levels of pressure support, RR, TV (mL), RR/TV, positive end expiratory pressure levels, FiO2 and SpO2 required during the weaning process, the need for reintubation and the need for non-invasive ventilation in the 48 hours after extubation. Results In the intention to treat analysis there were no statistically significant differences between the 53 patients selected for each group regarding gender (p = 0.541), age (p = 0.585) and type of surgery (p = 0.172). Nineteen patients presented complications during the trial (4 in the PSV manual group and 15 in the MRV automatic group, p < 0.05). Nine patients in the automatic group did not adapt to the MRV mode. The mean ± sd (standard deviation) duration of the weaning process was 221 ± 192 for the manual group, and 271 ± 369 minutes for the automatic group (p = 0.375). PSV levels were significantly higher in MRV compared with that of the PSV manual reduction (p < 0.05). Reintubation was not required in either group. Non-invasive ventilation was necessary for two patients, in the manual group after cardiac surgery (p = 0.51). Conclusions The duration of the automatic reduction of pressure support was similar to the manual one in the post-operative period in the ICU, but presented more complications, especially no adaptation to the MRV algorithm. Trial Registration Trial registration number: ISRCTN37456640
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- 2009
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45. ERGONOMIC RISK PROFILE OF CRITICALLY ILL PATIENTS
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EL Brasil, Raquel Afonso Caserta Eid, JA Souza Junior, Ffp Rodrigues, L Candido, CL Batista, Luis Ronan Marquez Ferreira de Souza, L Ayako, Jefferson Pereira e Silva, K Zarco, M Cosme, Karina T. Timenetsky, C Ayres, Cleber Carmo do Nascimento, and D Carnieli-Cazati
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medicine.medical_specialty ,Ergonomic risk ,business.industry ,Critically ill ,Total dependence ,Human factors and ergonomics ,Context (language use) ,Critical Care and Intensive Care Medicine ,Scale (social sciences) ,Poster Presentation ,Health care ,Physical therapy ,medicine ,Early mobilization ,business ,Intensive care medicine - Abstract
In early mobilization context as also for any type of critically ill patient mobility, there are different levels of patients' participation during the activity, going from total dependence to independence. In this sense, two aspects should be considered as the efficacy of safe procedures to the patient as well as for the health care team in order to minimize ergonomic risks. This ergonomic risk can be tracked through a specific scale, although so far there are no evidence of this ergonomic risk in critically ill patients.
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