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25 results on '"Rapaccini, GL (ORCID:0000-0002-6467-857X)"'

1. The role of antiplatelet therapies on incidence and mortality of hepatocellular carcinoma

Author

Lai, Quirino, De Matthaeis, Nicoletta, Finotti, Michele, Galati, Giovanni, Marrone, Giuseppe, Melandro, Fabio, Morisco, Filomena, Nicolini, Daniele, Pravisani, Riccardo, Giannini, Edoardo G, Aglitti, A, Aliberti, C, Baccarani, U, Bhoori, S, Borzio, M, Brancaccio, G, Burra, P, Cabibbo, G, Casadei Gardini, A, Carrai, P, Cillo, U, Conti, F, Cucchetti, A, D'Ambrosio, R, Dell'Unto, C, Di Costanzi, Gg, Di Sandro, S, Foschi, Fg, Fucilli, F, Gambato, M, Gasbarrini, Antonio, Giuliante, Felice, Ghinolfi, D, Grieco, Antonio, Gruttaduria, S, Guarino, M, Kostandini, A, Iavarone, M, Lenci, I, Levi Sandri, Gb, Losito, F, Lupo, Lg, Manzia, Tm, Mazzocato, S, Mescoli, C, Miele, Luca, Muley, M, Persico, M, Plaz Torres, Mc, Pompili, Maurizio, Ponziani, Francesca Romana, Rapaccini, Gian Ludovico, Rendina, M, Renzulli, M, Rossi, Marco, Rreka, E, Russo, Fp, Sacco, R, Sangiovanni, A, Sessa, A, Simonetti, N, Sposito, C, Tortora, R, Trevisani, F, Viganò, L, Viganò, M, Villa, E, Vincenzi, V, Violi, P, Vitale, A, Gasbarrini, A (ORCID:0000-0002-7278-4823), Giuliante, F (ORCID:0000-0001-9517-8220), Grieco, A (ORCID:0000-0002-0544-8993), Miele, L (ORCID:0000-0003-3464-0068), Pompili, M (ORCID:0000-0001-6699-7980), Ponziani, FR (ORCID:0000-0002-5924-6238), Rapaccini, GL (ORCID:0000-0002-6467-857X), Rossi, M (ORCID:0000-0002-4539-5670), Lai, Quirino, De Matthaeis, Nicoletta, Finotti, Michele, Galati, Giovanni, Marrone, Giuseppe, Melandro, Fabio, Morisco, Filomena, Nicolini, Daniele, Pravisani, Riccardo, Giannini, Edoardo G, Aglitti, A, Aliberti, C, Baccarani, U, Bhoori, S, Borzio, M, Brancaccio, G, Burra, P, Cabibbo, G, Casadei Gardini, A, Carrai, P, Cillo, U, Conti, F, Cucchetti, A, D'Ambrosio, R, Dell'Unto, C, Di Costanzi, Gg, Di Sandro, S, Foschi, Fg, Fucilli, F, Gambato, M, Gasbarrini, Antonio, Giuliante, Felice, Ghinolfi, D, Grieco, Antonio, Gruttaduria, S, Guarino, M, Kostandini, A, Iavarone, M, Lenci, I, Levi Sandri, Gb, Losito, F, Lupo, Lg, Manzia, Tm, Mazzocato, S, Mescoli, C, Miele, Luca, Muley, M, Persico, M, Plaz Torres, Mc, Pompili, Maurizio, Ponziani, Francesca Romana, Rapaccini, Gian Ludovico, Rendina, M, Renzulli, M, Rossi, Marco, Rreka, E, Russo, Fp, Sacco, R, Sangiovanni, A, Sessa, A, Simonetti, N, Sposito, C, Tortora, R, Trevisani, F, Viganò, L, Viganò, M, Villa, E, Vincenzi, V, Violi, P, Vitale, A, Gasbarrini, A (ORCID:0000-0002-7278-4823), Giuliante, F (ORCID:0000-0001-9517-8220), Grieco, A (ORCID:0000-0002-0544-8993), Miele, L (ORCID:0000-0003-3464-0068), Pompili, M (ORCID:0000-0001-6699-7980), Ponziani, FR (ORCID:0000-0002-5924-6238), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Rossi, M (ORCID:0000-0002-4539-5670)

Abstract

Aim To evaluate the impact of antiplatelet therapy (APT)on the incidence of hepatocellular carcinoma (HCC) and mortality following its treatment. Methods A systematic literature search was performed using PubMed and Cochrane Central Register of Controlled Trials Databases. Two HCC clinical settings were explored: (i) incidence, and (ii) death after any HCC treatment. Odds ratios (OR) and 95% confidence intervals (95%CI) were calculated to compare the pooled data between patients who received or did not receive APT. Results A total of 20 studies were identified, of whom 15 focused on HCC incidence, including 2,685,009 patients, and five on post-treatment death, including 3281 patients. APT was associated with an overall reduced risk of HCC incidence (OR: 0.63; 95%CI = 0.51-0.79; p < 0.001) as well as of post-treatment mortality (OR: 0.54; 95%CI = 0.35-0.83; p = 0.006). Conclusions Current data suggest that APT correlated with higher HCC incidence and poor overall survival following tumour treatment.

Published
2023

2. COVID-19 and hepatic involvement: The liver as a main actor of the pandemic novel

Author

Napodano, Cecilia, Pocino, Krizia, Stefanile, A, Marino, Mariapaola, Miele, Luca, Gulli, F, Basile, V, Pandolfi, Franco, Gasbarrini, Antonio, Rapaccini, Gian Ludovico, Basile, Umberto, Napodano, C (ORCID:0000-0002-8720-6284), Pocino, K (ORCID:0000-0003-2456-5308), Marino, M (ORCID:0000-0001-9155-6378), Miele, L (ORCID:0000-0003-3464-0068), Pandolfi, F (ORCID:0000-0001-8799-8173), Gasbarrini, A (ORCID:0000-0002-7278-4823), Rapaccini, GL (ORCID:0000-0002-6467-857X), Basile, U, Napodano, Cecilia, Pocino, Krizia, Stefanile, A, Marino, Mariapaola, Miele, Luca, Gulli, F, Basile, V, Pandolfi, Franco, Gasbarrini, Antonio, Rapaccini, Gian Ludovico, Basile, Umberto, Napodano, C (ORCID:0000-0002-8720-6284), Pocino, K (ORCID:0000-0003-2456-5308), Marino, M (ORCID:0000-0001-9155-6378), Miele, L (ORCID:0000-0003-3464-0068), Pandolfi, F (ORCID:0000-0001-8799-8173), Gasbarrini, A (ORCID:0000-0002-7278-4823), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Basile, U

Abstract

In the natural history of SARS-CoV-2 infection, liver injury is frequent but quite mild and it is defined as any liver damage occurring during disease progression and treatment of infection in patients with or without pre-existing liver diseases. The underlying mechanisms for hepatic injury in patients with COVID-19 are still unclear but the liver damage in SARS-CoV-2 infection seems to be directly caused by virus-induced cytopathic effects. In this review, we will summarize all data of updated literature, regarding the relationship between SARS-CoV-2 infection, acute response and liver involvement. An overview will be given on liver injury, liver transplant and the possible consequences of COVID-19 in patients with pre-existing liver diseases.

Published
2021

3. SARS-CoV2 RNA detection in a pancreatic pseudocyst sample

Author

Schepis, Tommaso, Larghi, Alberto Leonardo, Papa, A, Miele, Luca, Panzuto, F, De Biase, L, Annibale, B, Cattani, P, Rapaccini, Gian Ludovico, Schepis, T, Larghi, A, Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Schepis, Tommaso, Larghi, Alberto Leonardo, Papa, A, Miele, Luca, Panzuto, F, De Biase, L, Annibale, B, Cattani, P, Rapaccini, Gian Ludovico, Schepis, T, Larghi, A, Miele, L (ORCID:0000-0003-3464-0068), and Rapaccini, GL (ORCID:0000-0002-6467-857X)

Abstract

The involvement of gastrointestinal system in SARS-CoV2 related disease, COVID-19, is increasingly recognized. COVID-19 associated pancreatic injury has been suggested, but its correlation with pancreatic disease is still unclear. In this case report, we describe the detection of SARS-CoV2 RNA in a pancreatic pseudocyst fluid sample collected from a patient with SARS-CoV2 associated pneumonia and a pancreatic pseudocyst developed as a complication of an acute edematous pancreatitis. The detection of SARS-CoV2 within the pancreatic collection arise the question of whether this virus has a tropism for pancreatic tissue and whether it plays a role in pancreatic diseases occurrence. (C) 2020 IAP and EPC. Published by Elsevier B.V. All rights reserved.

Published
2020

4. Hepatic decompensation is the major driver of death in HCV-infected cirrhotic patients with successfully treated early hepatocellular carcinoma

Author

Cabibbo, Giuseppe, Petta, Salvatore, Barbara, Marco, Attardo, Simona, Bucci, Laura, Farinati, Fabio, Giannini, Edoardo G., Negrini, Giulia, Ciccarese, Francesca, Rapaccini, Gian Ludovico, Di Marco, Maria, Caturelli, Eugenio, Zoli, Marco, Borzio, Franco, Sacco, Rodolfo, Virdone, Roberto, Marra, Fabio, Mega, Andrea, Morisco, Filomena, Benvegnã1, Luisa, Gasbarrini, Antonio, Svegliati-Baroni, Gianluca, Foschi, Francesco Giuseppe, Olivani, Andrea, Masotto, Alberto, Nardone, Gerardo, Colecchia, Antonio, Persico, Marcello, Craxã¬, Antonio, Trevisani, Franco, Cammã&nbsp, Calogero, Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, Antonio (ORCID:0000-0002-7278-4823), Cabibbo, Giuseppe, Petta, Salvatore, Barbara, Marco, Attardo, Simona, Bucci, Laura, Farinati, Fabio, Giannini, Edoardo G., Negrini, Giulia, Ciccarese, Francesca, Rapaccini, Gian Ludovico, Di Marco, Maria, Caturelli, Eugenio, Zoli, Marco, Borzio, Franco, Sacco, Rodolfo, Virdone, Roberto, Marra, Fabio, Mega, Andrea, Morisco, Filomena, Benvegnã1, Luisa, Gasbarrini, Antonio, Svegliati-Baroni, Gianluca, Foschi, Francesco Giuseppe, Olivani, Andrea, Masotto, Alberto, Nardone, Gerardo, Colecchia, Antonio, Persico, Marcello, Craxã¬, Antonio, Trevisani, Franco, Cammã&nbsp, Calogero, Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, Antonio (ORCID:0000-0002-7278-4823)

Abstract

Background & Aims Assessment of long-term outcome is required in hepatitis C virus (HCV)-infected patients with cirrhosis, who have been successfully treated for Barcelona Clinic Liver Cancer (BCLC) stage A hepatocellular carcinoma (HCC). However, problems arise due to the lack of models accounting for early changes during follow-up. The aim of this study was to estimate the impact of early events (HCC recurrence or hepatic decompensation within 12 months of complete radiological response) on 5-year overall survival (OS) in a large cohort of patients with HCV and cirrhosis, successfully treated HCC. Methods A total of 328 consecutive Caucasian patients with HCV-related cirrhosis and BCLC stage 0/A HCC who had complete radiological response after curative resection or thermal ablation were prospectively recruited to this study. Primary endpoint of the study was 5-year OS. Independent baseline and time-dependent predictors of 5-year OS were identified by Cox model. Results The observed 5-year survival rate was 44%. The observed HCC early recurrence and early hepatic decompensation rate were 21% and 10%, respectively. Early hepatic decompensation (Hazard Ratio [HR] 7.52; 95% confidence intervals (CI): 1.23–13.48) and HCC early recurrence as time-dependent covariates (HR 2.50; 95%CI: 1.23–5.05), presence of esophageal varices at baseline (HR 1.66; 95% CI: 1.02–2.70) and age (HR 1.04; 95% CI: 1.02–1.07) were significantly associated with the 5-year OS. Conclusion Survival in HCV-infected patients with cirrhosis and successfully treated HCC is influenced by early hepatic decompensation. Our study indirectly suggests that direct-acting antiviral agents could improve OS of HCC patients through long-term preservation of liver function, resulting in a lower cirrhosis-related mortality and a greater change of receiving curative treatments. Lay summary Survival in hepatitis C virus (HCV) infected patients with cirrhosis and successfully treated hepatocell

Published
2017

5. ELF TEST IS A RELIABLE NON INVASIVE TEST FOR FIBROSIS IN NAFLD SUBJECTS

Author

Miele, Luca, De Michele, Teresa, Isgro, Ma, Marrone, Giuseppe, Cefalo, Chiara Maria Assunta, Biolato, Marco, Rapaccini, Gian Ludovico, Gasbarrini, Antonio, Zuppi, Cecilia, Grieco, Antonio, Miele, L (ORCID:0000-0003-3464-0068), De Michele, T, Marrone, G, Cefalo, C, Biolato, M, Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Zuppi, C (ORCID:0000-0003-4710-4934), Grieco, A (ORCID:0000-0002-0544-8993), Miele, Luca, De Michele, Teresa, Isgro, Ma, Marrone, Giuseppe, Cefalo, Chiara Maria Assunta, Biolato, Marco, Rapaccini, Gian Ludovico, Gasbarrini, Antonio, Zuppi, Cecilia, Grieco, Antonio, Miele, L (ORCID:0000-0003-3464-0068), De Michele, T, Marrone, G, Cefalo, C, Biolato, M, Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Zuppi, C (ORCID:0000-0003-4710-4934), and Grieco, A (ORCID:0000-0002-0544-8993)

Abstract

N/a

Published
2015

6. SCREENING FOR THE IDENTIFICATION OF AUTOIMMUNE OR LYMPHOPROLIFERATIVE ONSET IN PATIENTS NAiVE TO HCV ANTIVIRAL TREATMENT

Author

Gulli, F, Basile, Umberto, Colacicco, Luigi, Miele, Luca, De Matthaeis, Nicoletta, Cattani, P, Rapaccini, Gian Ludovico, Basile, U, Colacicco, L (ORCID:0000-0002-0039-3727), Miele, L (ORCID:0000-0003-3464-0068), De Matthaeis, N, Rapaccini, GL (ORCID:0000-0002-6467-857X), Gulli, F, Basile, Umberto, Colacicco, Luigi, Miele, Luca, De Matthaeis, Nicoletta, Cattani, P, Rapaccini, Gian Ludovico, Basile, U, Colacicco, L (ORCID:0000-0002-0039-3727), Miele, L (ORCID:0000-0003-3464-0068), De Matthaeis, N, and Rapaccini, GL (ORCID:0000-0002-6467-857X)

Abstract

n/A

Published
2015

7. Pilot Study on the Role of Multidisciplinary Approach in Risk Reduction of Risk of Non- alcoholic Fatty Liver in Subjects with Eating Disorders

Author

Cefalo, C, Strangio, A, Miele, L, Rinaldi, L, Marrone, G, Racco, S, Zanche, A, Rapaccini, Gl, Bria, P, Gasbarrini, A, Grieco, A, Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Cefalo, C, Strangio, A, Miele, L, Rinaldi, L, Marrone, G, Racco, S, Zanche, A, Rapaccini, Gl, Bria, P, Gasbarrini, A, Grieco, A, Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2013

8. Treatment of Portal Vein Tumor Thrombosis (PVTT) Can Impact Survival of Patients With Advanced HCC?

Author

Cesario, V, Rinninella, E, Ponziani, Fr, Garcovich, M, Roccarina, D, Campanale, M, Di Rienzo, Ta, Barbaro, F, Siciliano, M, Annicchiarico, Be, Pompili, M, Rapaccini, Gl, Riccardi, L, Grieco, A, Miele, L, Iezzi, R, De Gaetano, Am, Di Stasio, E, Gasbarrini, Gb, Bonomo, L, Zocco, Ma, Gasbarrini, A, Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Annicchiarico, BE, Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Miele, L (ORCID:0000-0003-3464-0068), Iezzi, R (ORCID:0000-0002-2791-481X), De Gaetano, AM (ORCID:0000-0002-7493-9462), Di Stasio, E (ORCID:0000-0003-1047-4261), Gasbarrini, GB, Bonomo, L (ORCID:0000-0001-5101-9367), Zocco, MA (ORCID:0000-0002-0814-9542), Gasbarrini, A (ORCID:0000-0002-7278-4823), Cesario, V, Rinninella, E, Ponziani, Fr, Garcovich, M, Roccarina, D, Campanale, M, Di Rienzo, Ta, Barbaro, F, Siciliano, M, Annicchiarico, Be, Pompili, M, Rapaccini, Gl, Riccardi, L, Grieco, A, Miele, L, Iezzi, R, De Gaetano, Am, Di Stasio, E, Gasbarrini, Gb, Bonomo, L, Zocco, Ma, Gasbarrini, A, Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Annicchiarico, BE, Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Miele, L (ORCID:0000-0003-3464-0068), Iezzi, R (ORCID:0000-0002-2791-481X), De Gaetano, AM (ORCID:0000-0002-7493-9462), Di Stasio, E (ORCID:0000-0003-1047-4261), Gasbarrini, GB, Bonomo, L (ORCID:0000-0001-5101-9367), Zocco, MA (ORCID:0000-0002-0814-9542), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2013

9. Personalized Therapy in a Multidisciplinary Team Improves Survival in Patient with HCC: The Hepatocatt Experience

Author

Rinninella, Emanuele, Ponziani, Francesca Romana, Biolato, Marco, Siciliano, M, D'Aversa, F, Laterza, L, Ianiro, Gianluca, Montagna, M, Tortora, Annalisa, Cesario, Valentina, Campanale, Mariachiara, De Matthaeis, Nicoletta, Miele, Luca, Riccardi, Laura, Zocco, Maria Assunta, Saviano, Angela, Abbate, Valeria, Avolio, Alfonso Wolfango, Vellone, Maria, Basso, M, Iezzi, Roberto, De Gaetano, Anna Maria, Bonomo, Lorenzo, Agnes, Salvatore, Giuliante, Felice, Vecchio, Fabio Maria, Barone, C, Rapaccini, Gian Ludovico, Pompili, Maurizio, Grieco, A, Gasbarrini, Antonio, Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Biolato, M, Ianiro, G (ORCID:0000-0002-8318-0515), Tortora, A, Cesario, V, Campanale, M, de Matthaeis, N, Miele, L (ORCID:0000-0003-3464-0068), Riccardi, L, Zocco, MA (ORCID:0000-0002-0814-9542), Saviano, A (ORCID:0000-0002-2820-7180), Abbate, V, Avolio, AW (ORCID:0000-0003-2491-7625), Vellone, M (ORCID:0000-0002-7628-4092), Iezzi, R (ORCID:0000-0002-2791-481X), De Gaetano, AM (ORCID:0000-0002-7493-9462), Bonomo, L (ORCID:0000-0001-5101-9367), Agnes, S (ORCID:0000-0002-3341-4221), Giuliante, F (ORCID:0000-0001-9517-8220), Vecchio, FM (ORCID:0000-0002-9197-2264), Rapaccini, GL (ORCID:0000-0002-6467-857X), Pompili, M (ORCID:0000-0001-6699-7980), Gasbarrini, A (ORCID:0000-0002-7278-4823), Rinninella, Emanuele, Ponziani, Francesca Romana, Biolato, Marco, Siciliano, M, D'Aversa, F, Laterza, L, Ianiro, Gianluca, Montagna, M, Tortora, Annalisa, Cesario, Valentina, Campanale, Mariachiara, De Matthaeis, Nicoletta, Miele, Luca, Riccardi, Laura, Zocco, Maria Assunta, Saviano, Angela, Abbate, Valeria, Avolio, Alfonso Wolfango, Vellone, Maria, Basso, M, Iezzi, Roberto, De Gaetano, Anna Maria, Bonomo, Lorenzo, Agnes, Salvatore, Giuliante, Felice, Vecchio, Fabio Maria, Barone, C, Rapaccini, Gian Ludovico, Pompili, Maurizio, Grieco, A, Gasbarrini, Antonio, Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Biolato, M, Ianiro, G (ORCID:0000-0002-8318-0515), Tortora, A, Cesario, V, Campanale, M, de Matthaeis, N, Miele, L (ORCID:0000-0003-3464-0068), Riccardi, L, Zocco, MA (ORCID:0000-0002-0814-9542), Saviano, A (ORCID:0000-0002-2820-7180), Abbate, V, Avolio, AW (ORCID:0000-0003-2491-7625), Vellone, M (ORCID:0000-0002-7628-4092), Iezzi, R (ORCID:0000-0002-2791-481X), De Gaetano, AM (ORCID:0000-0002-7493-9462), Bonomo, L (ORCID:0000-0001-5101-9367), Agnes, S (ORCID:0000-0002-3341-4221), Giuliante, F (ORCID:0000-0001-9517-8220), Vecchio, FM (ORCID:0000-0002-9197-2264), Rapaccini, GL (ORCID:0000-0002-6467-857X), Pompili, M (ORCID:0000-0001-6699-7980), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2013

10. New Therapeutic Perspectives for Management of Advanced Hepatocellular Carcinoma With Hepatic Arteriovenous Fistula: Balloon-Occluded Percutaneous Radio-Frequency Thermal Ablation (RFA) Plus Transcatheter Arterial Chemoembolization (TACE)

Author

Iezzi, R, Cesario, V, Campanale, M, Pecere, S, Barbaro, F, Rinninella, E, Ponziani, Fr, La Torre, M, Annicchiarico, Be, Siciliano, M, Pompili, M, Grieco, A, Miele, L, Rapaccini, Gl, Riccardi, L, Zocco, Ma, Milani, A, De Gaetano, Am, Gasbarrini, Gb, Bonomo, L, Gasbarrini, A, Iezzi, R (ORCID:0000-0002-2791-481X), Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Annicchiarico, BE, Pompili, M (ORCID:0000-0001-6699-7980), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Zocco, MA (ORCID:0000-0002-0814-9542), Milani, A (ORCID:0000-0003-1303-7737), De Gaetano, AM (ORCID:0000-0002-7493-9462), Gasbarrini, GB, Bonomo, L (ORCID:0000-0001-5101-9367), Gasbarrini, A (ORCID:0000-0002-7278-4823), Iezzi, R, Cesario, V, Campanale, M, Pecere, S, Barbaro, F, Rinninella, E, Ponziani, Fr, La Torre, M, Annicchiarico, Be, Siciliano, M, Pompili, M, Grieco, A, Miele, L, Rapaccini, Gl, Riccardi, L, Zocco, Ma, Milani, A, De Gaetano, Am, Gasbarrini, Gb, Bonomo, L, Gasbarrini, A, Iezzi, R (ORCID:0000-0002-2791-481X), Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Annicchiarico, BE, Pompili, M (ORCID:0000-0001-6699-7980), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Zocco, MA (ORCID:0000-0002-0814-9542), Milani, A (ORCID:0000-0003-1303-7737), De Gaetano, AM (ORCID:0000-0002-7493-9462), Gasbarrini, GB, Bonomo, L (ORCID:0000-0001-5101-9367), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2012

11. Single-Step Balloon-Occluded Percutaneous Radio-Frequency Thermal Ablation (RFA) Plus Transcatheter Arterial Chemoembolization (TACE) for Treatment of 'Complex' Unresectable Hepatocellular Carcinoma

Author

Iezzi, R, Cesario, V, Campanale, M, Di Rienzo, Ta, Gigante, G, Caracciolo, G, Rinninella, E, Ponziani, Fr, La Torre, M, Annicchiarico, Be, Siciliano, M, Pompili, M, Grieco, A, Miele, L, Rapaccini, Gl, Riccardi, L, Zocco, Ma, Milani, A, Santoro, M, De Gaetano, Am, Gasbarrini, Gb, Bonomo, L, Gasbarrini, A, Iezzi, R (ORCID:0000-0002-2791-481X), Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Annicchiarico, BE, Pompili, M (ORCID:0000-0001-6699-7980), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Zocco, MA (ORCID:0000-0002-0814-9542), Milani, A (ORCID:0000-0003-1303-7737), De Gaetano, AM (ORCID:0000-0002-7493-9462), Gasbarrini, GB, Bonomo, L (ORCID:0000-0001-5101-9367), Gasbarrini, A (ORCID:0000-0002-7278-4823), Iezzi, R, Cesario, V, Campanale, M, Di Rienzo, Ta, Gigante, G, Caracciolo, G, Rinninella, E, Ponziani, Fr, La Torre, M, Annicchiarico, Be, Siciliano, M, Pompili, M, Grieco, A, Miele, L, Rapaccini, Gl, Riccardi, L, Zocco, Ma, Milani, A, Santoro, M, De Gaetano, Am, Gasbarrini, Gb, Bonomo, L, Gasbarrini, A, Iezzi, R (ORCID:0000-0002-2791-481X), Rinninella, E (ORCID:0000-0002-9165-2367), Ponziani, FR (ORCID:0000-0002-5924-6238), Annicchiarico, BE, Pompili, M (ORCID:0000-0001-6699-7980), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Zocco, MA (ORCID:0000-0002-0814-9542), Milani, A (ORCID:0000-0003-1303-7737), De Gaetano, AM (ORCID:0000-0002-7493-9462), Gasbarrini, GB, Bonomo, L (ORCID:0000-0001-5101-9367), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2012

12. HCC PERSONALIZED TREATMENT IN THE MULTIMODAL MANAGEMENT ERA: THE HEPATOCAT GROUP EXPERIENCE

Author

Ponziani, Francesca Romana, Zocco, Maria Assunta, De Gaetano, Anna Maria, Novi, M, Siciliano, M, Milani, Alessandro, Annicchiarico, Eb, Miele, Luca, Rinninella, Emanuele, Tortora, Annalisa, Ainora, Maria Elena, Gasbarrini, Giovanni Battista, Agnes, Salvatore, Bombardieri, G, Giuliante, Felice, Grieco, A, Nuzzo, Gennaro, Pompili, Maurizio, Rapaccini, Gian Ludovico, Di Stasio, Enrico, Gasbarrini, Antonio, Ponziani, FR (ORCID:0000-0002-5924-6238), Zocco, MA (ORCID:0000-0002-0814-9542), De Gaetano, AM (ORCID:0000-0002-7493-9462), Milani, A (ORCID:0000-0003-1303-7737), Miele, L (ORCID:0000-0003-3464-0068), Rinninella, E (ORCID:0000-0002-9165-2367), Tortora, A, Ainora, ME, Gasbarrini, G, Agnes, S (ORCID:0000-0002-3341-4221), Giuliante, F (ORCID:0000-0001-9517-8220), Nuzzo, G, Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Di Stasio, E (ORCID:0000-0003-1047-4261), Gasbarrini, A (ORCID:0000-0002-7278-4823), Ponziani, Francesca Romana, Zocco, Maria Assunta, De Gaetano, Anna Maria, Novi, M, Siciliano, M, Milani, Alessandro, Annicchiarico, Eb, Miele, Luca, Rinninella, Emanuele, Tortora, Annalisa, Ainora, Maria Elena, Gasbarrini, Giovanni Battista, Agnes, Salvatore, Bombardieri, G, Giuliante, Felice, Grieco, A, Nuzzo, Gennaro, Pompili, Maurizio, Rapaccini, Gian Ludovico, Di Stasio, Enrico, Gasbarrini, Antonio, Ponziani, FR (ORCID:0000-0002-5924-6238), Zocco, MA (ORCID:0000-0002-0814-9542), De Gaetano, AM (ORCID:0000-0002-7493-9462), Milani, A (ORCID:0000-0003-1303-7737), Miele, L (ORCID:0000-0003-3464-0068), Rinninella, E (ORCID:0000-0002-9165-2367), Tortora, A, Ainora, ME, Gasbarrini, G, Agnes, S (ORCID:0000-0002-3341-4221), Giuliante, F (ORCID:0000-0001-9517-8220), Nuzzo, G, Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Di Stasio, E (ORCID:0000-0003-1047-4261), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2010

13. FIBROSIS PROGRESSION DURING SUNITINIB THERAPY IN CIRRHOTIC PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA

Author

Biolato, Marco, Basso, M, Forgione, Alessandra, Racco, S, Miele, Luca, Pompili, Maurizio, Rapaccini, Gian Ludovico, Landolfi, Raffaele, Barone, C, Grieco, A, Gasbarrini, Giovanni Battista, Biolato, M, Forgione, A, Miele, L (ORCID:0000-0003-3464-0068), Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Landolfi, R (ORCID:0000-0002-7913-8576), Gasbarrini, G, Biolato, Marco, Basso, M, Forgione, Alessandra, Racco, S, Miele, Luca, Pompili, Maurizio, Rapaccini, Gian Ludovico, Landolfi, Raffaele, Barone, C, Grieco, A, Gasbarrini, Giovanni Battista, Biolato, M, Forgione, A, Miele, L (ORCID:0000-0003-3464-0068), Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Landolfi, R (ORCID:0000-0002-7913-8576), and Gasbarrini, G

Abstract

n/a

Published
2010

14. Liver functional reserve and survival after sunitinib therapy in cirrhotic patients with advanced hepatocellular carcinoma

Author

Biolato, Marco, Basso, M, Cassano, A, Cefalo, Chiara Maria Assunta, Miele, Luca, Pompili, Maurizio, Rapaccini, Gian Ludovico, Gasbarrini, Giovanni Battista, Barone, C, Grieco, A, Biolato, M, Cefalo, C, Miele, L (ORCID:0000-0003-3464-0068), Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, G, Biolato, Marco, Basso, M, Cassano, A, Cefalo, Chiara Maria Assunta, Miele, Luca, Pompili, Maurizio, Rapaccini, Gian Ludovico, Gasbarrini, Giovanni Battista, Barone, C, Grieco, A, Biolato, M, Cefalo, C, Miele, L (ORCID:0000-0003-3464-0068), Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, G

Abstract

N/A

Published
2010

15. SERUM SODIUM IS A PREDICTOR OF SURVIVAL FOR 'INTERMEDIATE HCC' TREATED WITH TRANSARTERIAL CHEMIOEMBOLIZATION (TACE)

Author

Vero, V, Racco, S, Gabrieli, Ml, Pompili, M, Marrone, G, Forgione, A, Biolato, M, Cefalo, C, Di Stasi, C, Miele, L, Rapaccini, Gl, Grieco, A, Pompili, M (ORCID:0000-0001-6699-7980), Di Stasi, C (ORCID:0000-0002-6822-3599), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Vero, V, Racco, S, Gabrieli, Ml, Pompili, M, Marrone, G, Forgione, A, Biolato, M, Cefalo, C, Di Stasi, C, Miele, L, Rapaccini, Gl, Grieco, A, Pompili, M (ORCID:0000-0001-6699-7980), Di Stasi, C (ORCID:0000-0002-6822-3599), Miele, L (ORCID:0000-0003-3464-0068), and Rapaccini, GL (ORCID:0000-0002-6467-857X)

Abstract

N/A

Published
2009

16. THE 15 AND 30 MINUTES SAMPLING OF 13C-BREATH TESTING ARE ABLE TO PREDICT SEVERE HEPATIC FIBROSIS AND SEVERITY OF LIVER DISEASE

Author

Miele, L, Candelli, M, Marrone, G, Zocco, Ma, Biolato, M, Gigante, G, Racco, S, Cefalo, C, Pompili, M, Rapaccini, Gl, Grieco, A, Gasbarrini, A, Miele, L (ORCID:0000-0003-3464-0068), Candelli, M (ORCID:0000-0001-8443-7880), Zocco, MA (ORCID:0000-0002-0814-9542), Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Miele, L, Candelli, M, Marrone, G, Zocco, Ma, Biolato, M, Gigante, G, Racco, S, Cefalo, C, Pompili, M, Rapaccini, Gl, Grieco, A, Gasbarrini, A, Miele, L (ORCID:0000-0003-3464-0068), Candelli, M (ORCID:0000-0001-8443-7880), Zocco, MA (ORCID:0000-0002-0814-9542), Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2009

17. PREVALENCE OF LIVER STEATOSIS AND METABOLIC SYNDROME IN PATIENTS WITH PSORIASIS

Author

Miele, Luca, De Simone, Clara, Cefalo, Chiara Maria Assunta, Vallone, S, Gabrieli, Ml, Forgione, Alessandra, D'Agostino, Maria Antonietta, Bussoletti, C, Capizzi, Rodolfo, Racco, S, Pompilil, M, Gasbarrini, Giovanni Battista, Amerio, P, Rapaccini, Gian Ludovico, Grieco, A, Miele, L (ORCID:0000-0003-3464-0068), De Simone, C (ORCID:0000-0002-0898-0045), Cefalo, C, Forgione, A, Capizzi, R (ORCID:0000-0001-6149-9237), Gasbarrini, G, Rapaccini, GL (ORCID:0000-0002-6467-857X), Miele, Luca, De Simone, Clara, Cefalo, Chiara Maria Assunta, Vallone, S, Gabrieli, Ml, Forgione, Alessandra, D'Agostino, Maria Antonietta, Bussoletti, C, Capizzi, Rodolfo, Racco, S, Pompilil, M, Gasbarrini, Giovanni Battista, Amerio, P, Rapaccini, Gian Ludovico, Grieco, A, Miele, L (ORCID:0000-0003-3464-0068), De Simone, C (ORCID:0000-0002-0898-0045), Cefalo, C, Forgione, A, Capizzi, R (ORCID:0000-0001-6149-9237), Gasbarrini, G, and Rapaccini, GL (ORCID:0000-0002-6467-857X)

Abstract

N/A

Published
2008

18. Use of G-CSF during acute on chronic liver failure: Clinical and biochemical safety profile

Author

Novi, M, Di Campli, C, Di Gioacchino, G, Zocco, Maria Assunta, Rutella, S, Ainora, Maria Elena, Addolorato, Giovanni, Abenavoli, L, Miele, Luca, Forgione, Alessandra, Grieco, A, Leone, Maria Grazia, Gasbarrini, Giovanni Battista, Rapaccini, Gian Ludovico, Pola, P, Gasbarrini, Antonio, Zocco, MA (ORCID:0000-0002-0814-9542), Ainora, ME, Addolorato, G (ORCID:0000-0002-1522-9946), Miele, L (ORCID:0000-0003-3464-0068), Forgione, A, Leone, G, Gasbarrini, GB, Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Novi, M, Di Campli, C, Di Gioacchino, G, Zocco, Maria Assunta, Rutella, S, Ainora, Maria Elena, Addolorato, Giovanni, Abenavoli, L, Miele, Luca, Forgione, Alessandra, Grieco, A, Leone, Maria Grazia, Gasbarrini, Giovanni Battista, Rapaccini, Gian Ludovico, Pola, P, Gasbarrini, Antonio, Zocco, MA (ORCID:0000-0002-0814-9542), Ainora, ME, Addolorato, G (ORCID:0000-0002-1522-9946), Miele, L (ORCID:0000-0003-3464-0068), Forgione, A, Leone, G, Gasbarrini, GB, Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/a

Published
2006

19. CXCR4, vegfr and VLA-4 levels in peripheral blood lymphocytes of patients with acute on chronic liver failure treated with G-CSF

Author

Di Campli, C, Zocco, Ma, Natalie, S, Di Gioacchino, G, Rutella, S, Novi, M, Ainora, Me, Addolorato, G, Abenavoli, L, Miele, L, Forgione, A, Grieco, A, Leone, G, Gasbarrini, G, Rapaccini, Gl, Pola, P, Gasbarrini, A, Zocco, MA (ORCID:0000-0002-0814-9542), Ainora, ME, Addolorato, G (ORCID:0000-0002-1522-9946), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Di Campli, C, Zocco, Ma, Natalie, S, Di Gioacchino, G, Rutella, S, Novi, M, Ainora, Me, Addolorato, G, Abenavoli, L, Miele, L, Forgione, A, Grieco, A, Leone, G, Gasbarrini, G, Rapaccini, Gl, Pola, P, Gasbarrini, A, Zocco, MA (ORCID:0000-0002-0814-9542), Ainora, ME, Addolorato, G (ORCID:0000-0002-1522-9946), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2006

20. Prognosis of patients with hepatocellular carcinoma (HCC) according to Okuda staging system, CLIP staging system and BCLC staging classification: Results of a single Italian centre

Author

Caminiti, G, Pompili, Maurizio, Covino, Marcello, Alfei, B, Miele, Luca, Rapaccini, Gian Ludovico, Grieco, A, Gasbarrini, Giovanni Battista, Pompili, M (ORCID:0000-0001-6699-7980), Covino, M (ORCID:0000-0002-6709-2531), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, G, Caminiti, G, Pompili, Maurizio, Covino, Marcello, Alfei, B, Miele, Luca, Rapaccini, Gian Ludovico, Grieco, A, Gasbarrini, Giovanni Battista, Pompili, M (ORCID:0000-0001-6699-7980), Covino, M (ORCID:0000-0002-6709-2531), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, G

Abstract

n/a

Published
2003

21. Transarterial chemoembolization (TACE) for unresectable hepatocellular carcinoma in cirrhotics: Functional hepatic reserve and survival

Author

Grieco, A, Marcoccia, S, Miele, L, Marmiroli, L, Caminiti, G, Ragazzoni, E, Cotroneo, Ar, Cefaro, Ga, Rapaccini, Gl, Gasbarrini, G, Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Grieco, A, Marcoccia, S, Miele, L, Marmiroli, L, Caminiti, G, Ragazzoni, E, Cotroneo, Ar, Cefaro, Ga, Rapaccini, Gl, Gasbarrini, G, Miele, L (ORCID:0000-0003-3464-0068), and Rapaccini, GL (ORCID:0000-0002-6467-857X)

Abstract

Background/Aims: Transarterial chemoembolization is widely used for-palliative treatment of hepatocellular carcinoma, but patient's characteristics associated with maximal benefit are still undefined.Methodology: In 81 cirrhotic patients with unresectable hepatocegular carcinoma, who underwent transarterial chemoembolization, variables correlated with survival were studied. In 46/81, the antipyrine metabolism test has been performed before and 72 hours after first transarterial chemoembolization.Results: Mean overall survival of whole population was 22 months. One-, two-, and three-year survival rates were respectively 85%, 38.6%, and 18.1%. Better survival was observed in those patients who received more than one treatment (p=0.016), while no relationship was found with treatment response, drug used, or number of lobes involved. Univariate analysis of the subgroup with antipyrine pharmacokinetic data revealed a significant relation between survival and baseline albumin (p=0.039), total cholesterol. (p=0.036), AST (p=0.017), log of, total bilirubin (p=0.017), and Child-Pugh class (p=0.029), but not with parameters of antipyrine metabolism. Antipyrine metabolism was not significantly modified by transarterial chemoembolization in the, subgroup tested before,and, after the first treatment. Using Cox regression analysis and selecting AST and log of total bilirubin, a prognostic index was defined: prognostic index 0.006 (AST-83.044) + 0.638 [log of total bihrubin-0.1175]. One-, two-, and three-year survival rates were respectively 92%, 59.2%, and 29.6% for the patient group with prognostic index <0, and 7.6%, 14.3%, and 4.8% for the group with prognostic index >0 (p<0.01).Conclusions: Transarterial chemoembolization is a safe procedure and appears beneficial for those patients with a good functional hepatic reserve. The antipyrine metabolism test does not provide any additional prognostic information.

Published
2003

22. Serum markers of fibrogenesis and fibrosis in nonalcoholic steatohepatitis (NASH)

Author

Costanzo, M, Miele, Luca, Di Rocco, P, Forgione, Alessandra, Alfei, B, Pompili, Maurizio, Rapaccini, Gian Ludovico, Grieco, A, Gasbarrini, Giovanni Battista, Miele, L (ORCID:0000-0003-3464-0068), Forgione, A, Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, G, Costanzo, M, Miele, Luca, Di Rocco, P, Forgione, Alessandra, Alfei, B, Pompili, Maurizio, Rapaccini, Gian Ludovico, Grieco, A, Gasbarrini, Giovanni Battista, Miele, L (ORCID:0000-0003-3464-0068), Forgione, A, Pompili, M (ORCID:0000-0001-6699-7980), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, G

Abstract

N/a

Published
2002

23. Assessment of recent thymic emigrants (TRECs) in patients with HCV chronic hepatitis

Author

Di Campli, C, Pandolfi, Franco, Piscaglia, Anna Chiara, Urgesi, R, Cianci, Rossella, Miele, Luca, Grieco, A, Rapaccini, Gian Ludovico, Gasbarrini, Giovanni Battista, Gasbarrini, Antonio, Pandolfi, F (ORCID:0000-0001-8799-8173), Piscaglia, AC, Cianci, R (ORCID:0000-0001-5378-8442), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, G, Gasbarrini, A (ORCID:0000-0002-7278-4823), Di Campli, C, Pandolfi, Franco, Piscaglia, Anna Chiara, Urgesi, R, Cianci, Rossella, Miele, Luca, Grieco, A, Rapaccini, Gian Ludovico, Gasbarrini, Giovanni Battista, Gasbarrini, Antonio, Pandolfi, F (ORCID:0000-0001-8799-8173), Piscaglia, AC, Cianci, R (ORCID:0000-0001-5378-8442), Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, G, and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/a

Published
2002

24. Serum laminin levels in non alcoholic steatohepatitis

Author

Di Rocco, P, Grieco, A, Bianco, A, Caprodossi, A, Miele, Luca, Rapaccini, Gian Ludovico, Pompili, Maurizio, Greco, Av, Gasbarrini, Giovanni Battista, Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Pompili, M (ORCID:0000-0001-6699-7980), Gasbarrini, GB, Di Rocco, P, Grieco, A, Bianco, A, Caprodossi, A, Miele, Luca, Rapaccini, Gian Ludovico, Pompili, Maurizio, Greco, Av, Gasbarrini, Giovanni Battista, Miele, L (ORCID:0000-0003-3464-0068), Rapaccini, GL (ORCID:0000-0002-6467-857X), Pompili, M (ORCID:0000-0001-6699-7980), and Gasbarrini, GB

Abstract

N/A

Published
2001

25. Quantitative liver function tests to assess MEHOS activity in NASH patients

Author

Miele, L, Grieco, A, Armuzzi, A, Forgione, A, Ragazzoni, E, Zocco, Ma, Alfei, B, Rapaccini, Gl, Gasbarrini, G, Gasbarrini, A, Miele, L (ORCID:0000-0003-3464-0068), Armuzzi, A (ORCID:0000-0003-1572-0118), Zocco, MA (ORCID:0000-0002-0814-9542), Rapaccini, GL (ORCID:0000-0002-6467-857X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Miele, L, Grieco, A, Armuzzi, A, Forgione, A, Ragazzoni, E, Zocco, Ma, Alfei, B, Rapaccini, Gl, Gasbarrini, G, Gasbarrini, A, Miele, L (ORCID:0000-0003-3464-0068), Armuzzi, A (ORCID:0000-0003-1572-0118), Zocco, MA (ORCID:0000-0002-0814-9542), Rapaccini, GL (ORCID:0000-0002-6467-857X), and Gasbarrini, A (ORCID:0000-0002-7278-4823)

Abstract

N/A

Published
2001

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