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21 results on '"Ranjan, Sandip"'

9. Abstract P2-12-09: Correlation between pathologic complete response (pCR), event-free survival (EFS)/disease-free survival (DFS) and overall survival (OS) in neoadjuvant and/or adjuvant (NAdj/Adj) hormone receptor positive (HR+) and human epidermal growth factor receptor-2 negative (HER2-) breast cancer (BC)

Author

Gogate, Anagha, primary, Kim, Inkyu, additional, Ranjan, Sandip, additional, Kumar, Amit, additional, Papademetriou, Eros, additional, Bhandari, Hitesh, additional, and Potluri, Ravi, additional

Published
2022
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11. CC-486 Reduces Hospitalization and Associated Estimated Costs in Patients with Acute Myeloid Leukemia (AML) in First Remission after Intensive Chemotherapy: Results from the QUAZAR AML-001 Maintenance Trial

Author

Oliva, Esther Natalie, primary, Kambhampati, Suman, additional, Oriol, Albert, additional, La Torre, Ignazia, additional, Skikne, Barry, additional, Beach, C.L., additional, Kumar, Keshava, additional, Dong, Qian, additional, Chen, Clara, additional, Ranjan, Sandip, additional, Kiendrebeogo, Zephirin, additional, and Braun, Thorsten, additional

Published
2020
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16. The impact of ultraviolet light exposure on the performance of polybenzidimazole and polyaramid fabrics: Prediction of end-of-life performance.

Author

Houshyar, Shadi, Padhye, Rajiv, Ranjan, Sandip, Tew, Steve, and Nayak, Rajkishore

Subjects
ULTRAVIOLET radiation, PROTECTIVE clothing, FIRE fighters, MECHANICAL behavior of materials, WEATHERING, INDUSTRIAL textiles
Abstract

This study evaluated the deterioration in thermo-mechanical and performance properties of the polyaramid and polybenzidimazole fabric used in firefighters' protective clothing after exposure to ultraviolet irradiation, and the effect of weathering. The performance of firefighters' protective clothing plays an important role in protection against heat and physical threats to firefighters. However, frequent exposure to heat and ultraviolet irradiation can deteriorate performance. Test results demonstrated a 79% drop in the residual strength of polybenzidimazole/Kevlar® fabric and a 51% drop in the residual strength of polyaramid (Nomex® IIIA). The results confirmed that heat accelerates the degradation of PBI, resulting in lower performance, an important consideration for firefighters' protective clothing. In this study, a new 'UVPro-Tex' sensor was developed, with the capability to record the amount of ultraviolet irradiation absorbed by the fabric. When the amount of the absorbed ultraviolet irradiation reaches a critical value, the sensor warns the wearer of the end-of-life of the garment. [ABSTRACT FROM AUTHOR]

Published
2018
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20. The impact of super-absorbent materials on the thermo-physiological properties of textiles.

Author

Houshyar, Shadi, Padhye, Rajiv, Vijayan, Arun, Jadhav, Amit, and Ranjan, Sandip

Subjects
THERMAL insulation, PROTECTIVE clothing, FIRE fighters, HEAT transfer, WATER vapor
Abstract

The use of appropriate protective clothing systems in high-risk environments is absolutely essential. Such protective clothing may not provide the desired wearer comfort due to the complexities associated with the system. These constraints are largely due to the multiple layers involved in the protective ensemble. Firefighters’ protective clothing systems, in particular, have limited or no water vapor permeability. This prevents evaporative heat loss and leads to thermal strain and sweat accumulation. This accumulated sweat on the skin and on the internal layer close to the body causes considerable discomfort to the user due to the sensation of wetness. Extensive research has been done to improve the comfort properties of such protective clothing. This research adds yet another dimension where a new inner-layer construction has been developed with high liquid and vapor-absorption capacity that could assist in keeping the moisture and vapor away from the skin and, in addition, retain a dry microclimate close to the skin. The developed materials were tested for their biophysical properties that included tests such as thermal and water vapor resistance, air permeability and moisture management properties. Experimental results in this study indicated that super-absorbent materials, when incorporated into a woven textile material, showed enhanced wearer comfort. It was observed that these super-absorbent materials have the capability to quickly wick the moisture away from the body and, in doing so, have the tendency to keep the skin dry. [ABSTRACT FROM PUBLISHER]

Published
2015
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21. Treatment Sequencing Patterns Observed in Patients Treated Initially with Lenalidomide/Dexamethasone Combination As Frontline Multiple Myeloma Therapy

Author

Chen, Clara, Potluri, Ravi, Kanakamedala, Hemanth, Papademetriou, Eros, Yasenchak, Christopher A., Ranjan, Sandip, Bhandari, Hitesh, Mann, Jasdeep, and Davis, Catherine

Abstract

Introduction: Doublet combinations including lenalidomide (len) and dexamethasone (dex; Ld) are increasingly used to treat frontline (FL) multiple myeloma (MM) patients (pts). Len has also been used as maintenance therapy where strategies increasing len dose with first relapse have been considered (Harousseau JL et al. Blood2017). Triplet combinations are emerging as standard of care for relapsed/refractory (RR) MM and the treatment paradigm is shifting, with new agents like carfilzomib, ixazomib, elotuzumab, and daratumumab being added to Ld. Although these new combinations have shown improved clinical outcomes in RRMM, most pts ultimately relapse. Thus, treatment decision with each relapse becomes increasingly important to improve survival; the most critical decision may come at first relapse. With earlier len use, better understanding of treatment sequencing patterns of len and its use in clinical practice settings may help optimize treatment strategies in RRMM pts in later lines. We present real-world clinical practice data on treatment sequencing at relapse from len-based FL therapy.

Published
2017
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